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Clark Lantz

Research Profile

Anatomy

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Smoke Inhalation Injury

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TOP 3
Cara L Sherwood; R Clark Lantz; Scott Boitano
Chronic arsenic exposure in nanomolar concentrations compromises wound response and intercellular signaling in airway epithelial cells.
Yi Zheng; Binh Chau; Jie Chen; Deyu Fang; R Clark Lantz; Fangru Lian; Guifan Sun; Shasha Tao; Donna D Zhang
Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response.
J Christopher States; John F Reichard; Aaron Barchowsky; Iain L Cartwright; Bernard W Futscher; R Clark Lantz
Arsenic toxicology: translating between experimental models and human pathology.

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All Publications

2013: Cara L Sherwood; R Clark Lantz; Scott Boitano
Chronic arsenic exposure in nanomolar concentrations compromises wound response and intercellular signaling in airway epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 2013;132(1):222-34.
2012: Yi Zheng; Binh Chau; Jie Chen; Deyu Fang; R Clark Lantz; Fangru Lian; Guifan Sun; Shasha Tao; Donna D Zhang
Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response.
Toxicology and applied pharmacology 2012;265(3):292-9.
2011: J Christopher States; John F Reichard; Aaron Barchowsky; Iain L Cartwright; Bernard W Futscher; R Clark Lantz
Arsenic toxicology: translating between experimental models and human pathology.
Environmental health perspectives 2011;119(10):1356-63.
2011: Simon S Wong; Jefferey L Burgess; Cynthia Fastje; Craig J Gerard; R Clark Lantz; Bao Lu; Duane L Sherrill; Nina N Sun; Mark L Witten
Role of neprilysin in airway inflammation induced by diesel exhaust emissions.
Research report (Health Effects Institute) 2011;(159):3-40.
2009: Jay S Petrick; Francoise M Blachere; Ornella Selmin; R Clark Lantz
Inorganic arsenic as a developmental toxicant: in utero exposure and alterations in the developing rat lungs.
Molecular nutrition & food research 2009;53(5):583-91.
2009: R Clark Lantz; Binh Chau; Priyanka Sarihan; Mark L Witten; Vadim I Pivniouk; Guan Jie Chen
In utero and postnatal exposure to arsenic alters pulmonary structure and function.
Toxicology and applied pharmacology 2009;235(1):105-13.
2008: Simon S Wong; Jason Vargas; Alana Thomas; Cindy Fastje; Michael McLaughlin; Ryan Camponovo; R Clark Lantz; Jeffrey Heys; Mark L Witten
In vivo comparison of epithelial responses for S-8 versus JP-8 jet fuels below permissible exposure limit.
Toxicology 2008;254(1-2):106-11.
2008: Allison M Hays; R Clark Lantz; Laurel S Rodgers; James J Sollome; Richard R Vaillancourt; angeline andrew; Joshua W Hamilton; Todd D Camenisch
Arsenic-induced decreases in the vascular matrix.
Toxicologic pathology 2008;36(6):805-17.
2008: Colin E Olsen; Andrew E Liguori; Yue Zong; R Clark Lantz; Jefferey L Burgess; Scott Boitano
Arsenic upregulates MMP-9 and inhibits wound repair in human airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2008;295(2):L293-302.
2007: Jefferey L Burgess; Maria Mercedes Meza; Arun B Josyula; Gerald S Poplin; Michael J Kopplin; Hannah E McClellen; Stefan Stürup; R Clark Lantz
Environmental Arsenic Exposure and Urinary 8-OHdG in Arizona and Sonora.
Clinical toxicology (Philadelphia, Pa.) 2007;45(5):490-8.
2007: R Clark Lantz; Brandon J Lynch; Scott Boitano; Gerald S Poplin; Sally Littau; George Tsaprailis; Jefferey L Burgess
Pulmonary biomarkers based on alterations in protein expression after exposure to arsenic.
Environmental health perspectives 2007;115(4):586-91.
2007: R Clark Lantz; Guan Jie Chen; M Sarihan; Anikó M Sólyom; Shivanand D Jolad; Barbara N Timmermann
The effect of extracts from ginger rhizome on inflammatory mediator production.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2007;14(2-3):123-8.
2007: Nina N Sun; Simon S Wong; Celine Nardi; Daniel Ostroff; Mark L Witten; R Clark Lantz
In Vitro Pro-inflammatory Regulatory role of Substance P in Alveolar Macrophages and Type II Pneumocytes after JP-8 Exposure.
Journal of immunotoxicology 2007;4(1):61-7.
2006: Janet L Funk; Jennifer B Frye; Janice N Oyarzo; Nesrin Kuscuoglu; Jonathan Wilson; Gwen McCaffrey; Gregory Stafford; Guanjie Chen; R Clark Lantz; Shivanand D Jolad; Anikó M Sólyom; Pawel Kiela; Barbara N Timmermann
Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis.
Arthritis and rheumatism 2006;54(11):3452-64.
2006: Bradley R Herrin; Jessica E Haley; R Clark Lantz; Mark L Witten
A reevaluation of the threshold exposure level of inhaled JP-8 in mice.
The Journal of toxicological sciences 2006;31(3):219-28.
2006: Janet L Funk; Janice N Oyarzo; Jennifer B Frye; Guanjie Chen; R Clark Lantz; Shivanand D Jolad; Anikó M Sólyom; Barbara N Timmermann
Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis.
Journal of natural products 2006;69(3):351-5.
2006: R Clark Lantz; Allison M Hays
Role of oxidative stress in arsenic-induced toxicity.
Drug metabolism reviews 2006;38(4):791-804.
2006: Allison M Hays; Dinesh Srinivasan; Mark L Witten; Dean E Carter; R Clark Lantz
Arsenic and cigarette smoke synergistically increase DNA oxidation in the lung.
Toxicologic pathology 2006;34(4):396-404.
2005: Diane M Stearns; Monica Yazzie; Andrew S Bradley; Virginia H Coryell; Jake T Shelley; Adam Ashby; Craig S Asplund; R Clark Lantz
Uranyl acetate induces hprt mutations and uranium-DNA adducts in Chinese hamster ovary EM9 cells.
Mutagenesis 2005;20(6):417-23.
2005: Shivanand D Jolad; R Clark Lantz; Guan Jie Chen; Robert B Bates; Barbara N Timmermann
Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production.
Phytochemistry 2005;66(13):1614-35.
2005: R Clark Lantz; Guan Jie Chen; A M Solyom; Shivanand D Jolad; Barbara N Timmermann
The effect of turmeric extracts on inflammatory mediator production.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2005;12(6-7):445-52.
2004: Jefferey L Burgess; Maria A Fierro; R Clark Lantz; Tracy A Hysong; Joy E Fleming; Richard Gerkin; Eva Hnizdo; Shannon M Conley; Walter Klimecki
Longitudinal decline in lung function: evaluation of interleukin-10 genetic polymorphisms in firefighters.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2004;46(10):1013-22.
2004: Simon S Wong; Nina N Sun; R Clark Lantz; Mark L Witten
Substance P and neutral endopeptidase in development of acute respiratory distress syndrome following fire smoke inhalation.
American journal of physiology. Lung cellular and molecular physiology 2004;287(4):L859-66.
2004: Shivanand D Jolad; R Clark Lantz; Aniko M Solyom; Guan Jie Chen; Robert B Bates; Barbara N Timmermann
Fresh organically grown ginger (Zingiber officinale): composition and effects on LPS-induced PGE2 production.
Phytochemistry 2004;65(13):1937-54.
2004: Simon S Wong; Juanita Hyde; Nina N Sun; R Clark Lantz; Mark L Witten
Inflammatory responses in mice sequentially exposed to JP-8 jet fuel and influenza virus.
Toxicology 2004;197(2):139-47.
2003: R Clark Lantz; Jose A Orozco; Matthew S Bogdanffy
Vinyl acetate decreases intracellular pH in rat nasal epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 2003;75(2):423-31.
2003: Allison M Hays; R Clark Lantz; Mark L Witten
Correlation between in vivo and in vitro pulmonary responses to jet propulsion fuel-8 using precision-cut lung slices and a dynamic organ culture system.
Toxicologic pathology 2003;31(2):200-7.
2002: Jon L Freels; Dan K Nelson; Jeffrey C Hoyt; Michael Habib; Hiroki Numanami; R Clark Lantz; Richard A Robbins
Enhanced activity of human IL-10 after nitration in reducing human IL-1 production by stimulated peripheral blood mononuclear cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4568-71.
2002: Simon S Wong; Nina N Sun; R Clark Lantz; Mark L Witten
Tissue-specific patterns of neurokinin-1 receptor (NK-1R) gene expression in mice exposed to sidestream cigarette smoke.
Toxicology and industrial health 2002;18(9-10):435-44.
2002: Jefferey L Burgess; Christopher J Nanson; Tracy A Hysong; Richard Gerkin; Mark L Witten; R Clark Lantz
Rapid decline in sputum IL-10 concentration following occupational smoke exposure.
Inhalation toxicology 2002;14(2):133-40.
2001: Jayanthika Wijeweera; A Gandolfi; Alan R Parrish; R Clark Lantz
Sodium arsenite enhances AP-1 and NFkappaB DNA binding and induces stress protein expression in precision-cut rat lung slices.
Toxicological sciences : an official journal of the Society of Toxicology 2001;61(2):283-94.
2001: Jefferey L Burgess; Christopher J Nanson; D M Bolstad-Johnson; Richard Gerkin; Tracy A Hysong; R Clark Lantz; Duane L Sherrill; CD Crutchfield; Stuart F Quan; Alfred M Bernard; Mark L Witten
Adverse respiratory effects following overhaul in firefighters.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2001;43(5):467-73.
2001: R Clark Lantz; Ranulfo Lemus; Robert W Lange; Meryl H Karol
Rapid reduction of intracellular glutathione in human bronchial epithelial cells exposed to occupational levels of toluene diisocyanate.
Toxicological sciences : an official journal of the Society of Toxicology 2001;60(2):348-55.
2000: RF Robledo; R Scott Young; R Clark Lantz; Mark L Witten
Short-term pulmonary response to inhaled JP-8 jet fuel aerosol in mice.
Toxicologic pathology 2000;28(5):656-63.
2000: K A Anderson; RJ Lemen; N S Weger; H Chen; M C Bowers; Mark L Witten; R Clark Lantz; David E Bice; B A Muggenburg
Nedocromil sodium inhibits canine adenovirus bronchiolitis in beagle puppies.
Toxicologic pathology 2000;28(2):317-25.
1999: Shengjun Wang; R Clark Lantz; M W Vermeulen; G J Chen; V Breceda; RF Robledo; Allison M Hays; S Young; Mark L Witten
Functional alterations of alveolar macrophages subjected to smoke exposure and antioxidant lazaroids.
Toxicology and industrial health 1999;15(5):464-9.
1999: Robert W Lange; R Clark Lantz; Donna B Stolz; simon simon watkins; P Sundareshan; Ranulfo Lemus; Meryl H Karol
Toluene diisocyanate colocalizes with tubulin on cilia of differentiated human airway epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology 1999;50(1):64-71.
1999: Shengjun Wang; R Clark Lantz; RF Robledo; V Breceda; Allison M Hays; Mark L Witten
Early alterations of lung injury following acute smoke exposure and 21-aminosteroid treatment.
Toxicologic pathology 1999;27(3):334-41.
1998: NC Hoglen; Husam S Younis; D P Hartley; L Gunawardhana; R Clark Lantz; I Glenn Sipes
1,2-Dichlorobenzene-induced lipid peroxidation in male Fischer 344 rats is Kupffer cell dependent.
Toxicological sciences : an official journal of the Society of Toxicology 1998;46(2):376-85.
1997: Mark L Witten; J P Tinajero; R E Sobonya; R Clark Lantz; Stuart F Quan; RJ Lemen
Human alveolar fractal dimension in normal and chronic obstructive pulmonary disease subjects.
Research communications in molecular pathology and pharmacology 1997;98(2):221-30.
1997: NC Hoglen; E A Abril; John-Michael Sauer; D L Earnest; Robert S McCuskey; R Clark Lantz; S A Mobley; I Glenn Sipes
Modulation of Kupffer cell and peripheral blood monocyte activity by in vivo treatment of rats with all-trans-retinol.
Liver 1997;17(3):157-65.
1997: J P Tinajero; RF Robledo; R Clark Lantz; R E Sobonya; Stuart F Quan; RJ Lemen; B J Tollinger; Mark L Witten
Fractal analysis of lung alveoli during the acute phase vs. repair phase of an adenoviral infection in canines.
Research communications in molecular pathology and pharmacology 1997;95(3):275-85.
1997: Shengjun Wang; R Clark Lantz; E D Rider; G J Chen; V Breceda; Allison M Hays; RF Robledo; B J Tollinger; S V Dinesh; Mark L Witten
A free radical scavenger (Lazaroid U75412E) attenuates tumor necrosis factor-alpha generation in a rabbit model of smoke-induced lung injury.
Respiration; international review of thoracic diseases 1997;64(5):358-63.
1996: Shengjun Wang; R Clark Lantz; G J Chen; V Breceda; E Rider; Allison M Hays; G Parliman; B J Tollinger; RF Robledo; K Kunke; J Tinajero; Mark L Witten
The prophylactic effects of U75412E pretreatment in a smoke-induced lung injury rabbit model.
Pharmacology & toxicology 1996;79(5):231-7.
1996: J K Pfaff; B J Tollinger; R Clark Lantz; H Chen; Allison M Hays; Mark L Witten
Neutral endopeptidase (NEP) and its role in pathological pulmonary change with inhalation exposure to JP-8 jet fuel.
Toxicology and industrial health 1996;12(1):93-103.
1995: J Pfaff; K Parton; R Clark Lantz; H Chen; Allison M Hays; Mark L Witten
Inhalation exposure to JP-8 jet fuel alters pulmonary function and substance P levels in Fischer 344 rats.
Journal of applied toxicology : JAT 1995;15(4):249-56.
1995: W H Guilford; R Clark Lantz; R W Gore
Locomotive forces produced by single leukocytes in vivo and in vitro.
The American journal of physiology 1995;268(5 Pt 1):C1308-12.
1995: Allison M Hays; G Parliman; J K Pfaff; R Clark Lantz; J Tinajero; B Tollinger; J N Hall; Mark L Witten
Changes in lung permeability correlate with lung histology in a chronic exposure model.
Toxicology and industrial health 1995;11(3):325-36.
1995: R Clark Lantz; G Parliman; G J Chen; D Barber; S Winski; Dean E Carter
Effect of arsenic exposure on alveolar macrophage function. II. Effect of slightly soluble forms of As(III) and As(V).
Environmental research 1995;68(1):59-67.
1994: R Clark Lantz; G Parliman; G J Chen; Dean E Carter
Effect of arsenic exposure on alveolar macrophage function. I. Effect of soluble as(III) and as(V).
Environmental research 1994;67(2):183-95.
1993: M P Habib; D L Lackey; R Clark Lantz; R E Sobonya; R Grad; D L Earnest; John W Bloom
Vitamin A pretreatment and bleomycin induced rat lung injury.
Research communications in chemical pathology and pharmacology 1993;81(2):199-208.
1993: R Clark Lantz; RJ Lemen; Richard D Dey; A Rodd; M Bowers; H Chen; Mark L Witten; Stuart F Quan; R Kage; S E Leeman
Nedocromil preserves neuropeptides in neurons associated with airway smooth muscle and reduces adenovirus-induced airway hyperreactivity.
Regulatory peptides 1993;46(1-2):211-3.
1993: Mark L Witten; J L McKee; R Clark Lantz; Allison M Hays; Stuart F Quan; R E Sobonya; RJ Lemen
Fractal and morphometric analysis of lung structures after canine adenovirus-induced bronchiolitis in beagle puppies.
Pediatric pulmonology 1993;16(1):62-8.
1992: M A Brown; R Clark Lantz; R Sobonya; L C Devine; L A Lentz; RJ Lemen
Aerosolized lipopolysaccharide increases pulmonary clearance of 99mTc-DTPA in rabbits.
The American review of respiratory disease 1992;146(6):1462-8.
1992: Mark L Witten; R Grad; Stuart F Quan; R Clark Lantz; R E Sobonya; RJ Lemen
Effects of respiratory viruses on pulmonary alveolar macrophages.
Pediatric pulmonology 1992;12(2):105-12.
1991: Mark L Witten; R Clark Lantz; R Grad; S Seidner; Andrea K Hubbard; Stuart F Quan; RJ Lemen
Effect of smoke inhalation on immediate changes in lung chemical mediators.
Research communications in chemical pathology and pharmacology 1991;74(3):259-72.
1991: R Clark Lantz; G E Keller; R Burrell
The role of platelet-activating factor in the pulmonary response to inhaled bacterial endotoxin.
The American review of respiratory disease 1991;144(1):167-72.
1990: Mark L Witten; R Grad; Stuart F Quan; R E Sobonya; Andrea K Hubbard; R Clark Lantz; L A Lentz; L C Devine; RJ Lemen
Piriprost pretreatment attenuates the smoke-induced increase in 99mTcDTPA lung clearance.
Experimental lung research 1990;16(4):339-53.
1989: J A Hampton; R Clark Lantz; D E Hinton
Functional units in rainbow trout (Salmo gairdneri, Richardson) liver: III. Morphometric analysis of parenchyma, stroma, and component cell types.
The American journal of anatomy 1989;185(1):58-73.
1988: J A Hampton; R Clark Lantz; P J Goldblatt; D J Lauren; D E Hinton
Functional units in rainbow trout (Salmo gairdneri, Richardson) liver: II. The biliary system.
The Anatomical record 1988;221(2):619-34.
1988: Ragnar Rylander; L Beijer; R Clark Lantz; R Burrell; P Sedivy
Modulation of pulmonary inflammation after endotoxin inhalation with a platelet-activating factor antagonist (48740 RP).
International archives of allergy and applied immunology 1988;86(3):303-7.
1988: R Burrell; R Clark Lantz; D E Hinton
Mediators of pulmonary injury induced by inhalation of bacterial endotoxin.
The American review of respiratory disease 1988;137(1):100-5.
1987: D E Hinton; R Clark Lantz; J A Hampton; P R McCuskey; R S McCuskey
Normal versus abnormal structure: considerations in morphologic responses of teleosts to pollutants.
Environmental health perspectives 1987;71():139-46.
1986: R Clark Lantz; D E Hinton
Development of alterations in hamster distal lung following exposure to fly ash from fluidized bed coal combustion: a morphometric study.
Toxicology and applied pharmacology 1986;82(1):132-9.
1985: R Clark Lantz; K Birch; D E Hinton; R Burrell
Morphometric changes of the lung induced by inhaled bacterial endotoxin.
Experimental and molecular pathology 1985;43(3):305-20.
1984: R Clark Lantz; D E Hinton
Pulmonary toxicity associated with fly ash from fluidized bed coal combustion. II. Cellular morphometry of distal lung following a single intratracheal instillation.
Toxicology and applied pharmacology 1984;75(1):44-51.
1984: D E Hinton; R Clark Lantz; J A Hampton
Effect of age and exposure to a carcinogen on the structure of the medaka liver: a morphometric study.
National Cancer Institute monograph 1984;65():239-49.
1982: G S Jones; P R Miles; R Clark Lantz; D E Hinton; V Castranova
Ionic content and regulation of cellular volume in rat alveolar type II cells.
Journal of applied physiology: respiratory, environmental and exercise physiology 1982;53(1):258-66.
1981: E M Zuchelkowski; R Clark Lantz; D E Hinton
Effects of acid-stress on epidermal mucous cells of the brown bullhead Ictalurus nebulosus (LeSeur): a morphometric study.
The Anatomical record 1981;200(1):33-9.