FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

François Lanza

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Disorders

Physiology

Procedures

Flow Cytometry

Concepts & Ideas

Cell Shape

Co-author Network

Publications

TOP 3
M Schaff; Philippe Ohlmann; N Receveur; C Bourdon; Christian Gachet; François Lanza; Pierre Mangin
β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function.
Anita Eckly; François Lanza; Catherine Léon; Catherine Strassel; Jean-Pierre Cazenave; Christian Gachet
Characterization of megakaryocyte development in the native bone marrow environment.
Catherine Strassel; Catherine Léon; Sylvie Moog; Jean-Pierre Cazenave; Anita Eckly; Christian Gachet; François Lanza
Hirudin and heparin enable efficient megakaryocyte differentiation of mouse bone marrow progenitors.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of François Lanza (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: M Schaff; Philippe Ohlmann; N Receveur; C Bourdon; Christian Gachet; François Lanza; Pierre Mangin
β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function.
Thrombosis and haemostasis 2012;107(4):735-48.
2012: Anita Eckly; François Lanza; Catherine Léon; Catherine Strassel; Jean-Pierre Cazenave; Christian Gachet
Characterization of megakaryocyte development in the native bone marrow environment.
Methods in molecular biology (Clifton, N.J.) 2012;788():175-92.
2012: Catherine Strassel; Catherine Léon; Sylvie Moog; Jean-Pierre Cazenave; Anita Eckly; Christian Gachet; François Lanza
Hirudin and heparin enable efficient megakaryocyte differentiation of mouse bone marrow progenitors.
Experimental cell research 2012;318(1):25-32.
2011: A Eckly; B Hechler; M Freund; M Zerr; Jean-Pierre Cazenave; François Lanza; P H Mangin; Christian Gachet
Mechanisms underlying FeCl3-induced arterial thrombosis.
Journal of thrombosis and haemostasis : JTH 2011;9(4):779-89.
2011: Mathieu Schaff; Nicolas Receveur; Catherine Bourdon; Virginie Wurtz; Cécile V Denis; Gertraud Orend; Christian Gachet; François Lanza; Pierre H Mangin
Novel function of tenascin-C, a matrix protein relevant to atherosclerosis, in platelet recruitment and activation under flow.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(1):117-24.
2010: B Maître; P H Mangin; A Eckly; V Heim; Jean-Pierre Cazenave; François Lanza; Daniel Hanau; Christian Gachet
Immature myeloid dendritic cells capture and remove activated platelets from preformed aggregates.
Journal of thrombosis and haemostasis : JTH 2010;8(10):2262-72.
2010: Catherine Ravanat; Catherine Strassel; Béatrice Hechler; Simone Schuhler; Gaëtan Chicanne; Bernard Payrastre; Christian Gachet; François Lanza
A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbalpha N-terminal extracellular domain.
Blood 2010;116(7):1157-64.
2009: Sandra Eliautou; Pierre Henri Mangin; Ulrich Walter; Christian Gachet; François Lanza
Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists.
Thrombosis and haemostasis 2009;102(4):792-4.
2009: Catherine Strassel; Anita Eckly; Catherine Léon; Claire Petitjean; Monique Freund; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome.
Haematologica 2009;94(6):800-10.
2009: Anita Eckly; Catherine Strassel; Monique Freund; Jean-Pierre Cazenave; François Lanza; Christian Gachet; Catherine Léon
Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation.
Blood 2009;113(14):3182-9.
2009: Catherine Ravanat; Virginie Wurtz; Philippe Ohlmann; Marie Fichter; Jean-Pierre Cazenave; Alain Vandorsselaer; François Lanza; Christian Gachet
Use of tandem Biacore-mass spectrometry to identify platelet membrane targets of novel monoclonal antibodies.
Analytical biochemistry 2009;386(2):237-43.
2008: Boris Aleil; Laurence Kessler; Nicolas Meyer; Marie-Louise Wiesel; Julia Simeoni; Jean-Pierre Cazenave; Michel Pinget; Christian Gachet; François Lanza
Plasma levels of soluble platelet glycoprotein V are linked to fasting blood glucose in patients with type 2 diabetes.
Thrombosis and haemostasis 2008;100(4):713-5.
2008: christelle nonne; Béatrice Hechler; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Reassessment of in vivo thrombus formation in glycoprotein V deficient mice backcrossed on a C57Bl/6 strain.
Journal of thrombosis and haemostasis : JTH 2008;6(1):210-2.
2007: Catherine Léon; Anita Eckly; Béatrice Hechler; Boris Aleil; Monique Freund; Catherine Ravanat; Marie Jourdain; christelle nonne; Josiane Weber; Ralph Tiedt; Marie-Pierre Gratacap; Sonia Severin; Jean-Pierre Cazenave; François Lanza; Radek C Skoda; Christian Gachet
Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.
Blood 2007;110(9):3183-91.
2007: Catherine Strassel; christelle nonne; Anita Eckly; Tovo David; C Leon; Monique Freund; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Decreased thrombotic tendency in mouse models of the Bernard-Soulier syndrome.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):241-7.
2006: Tovo David; Philippe Ohlmann; Anita Eckly; Sylvie Moog; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Inhibition of adhesive and signaling functions of the platelet GPIb-V-IX complex by a cell penetrating GPIbalpha peptide.
Journal of thrombosis and haemostasis : JTH 2006;4(12):2645-55.
2006: Boris Aleil; Nicolas Meyer; Valérie Wolff; Daniel Kientz; Marie-Louise Wiesel; Christian Gachet; Jean-Pierre Cazenave; François Lanza
Plasma glycoprotein V levels in the general population: normal distribution, associated parameters and implications for clinical studies.
Thrombosis and haemostasis 2006;96(4):505-11.
2006: Christian Gachet; Béatrice Hechler; christelle nonne; Jean-Pierre Cazenave; François Lanza; Boris Aleil
[Atherothrombosis: transposition of the models to the clinic and reciprocally].
Thérapie 2006;61(5):389-94.
2006: Pierre Mangin; Cindy L Yap; christelle nonne; Sharelle A Sturgeon; Isaac Goncalves; Yuping Yuan; Simone M Schoenwaelder; Christine E Wright; François Lanza; Shaun P Jackson
Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency.
Blood 2006;107(11):4346-53.
2006: Béatrice Hechler; christelle nonne; Eun Joo Roh; Marco Cattaneo; Jean-Pierre Cazenave; François Lanza; Kenneth Alan Jacobson; Christian Gachet
MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice.
The Journal of pharmacology and experimental therapeutics 2006;316(2):556-63.
2006: Catherine Strassel; Tovo David; Anita Eckly; Marie-Jeanne Baas; Sylvie Moog; Catherine Ravanat; Marie C Trzeciak; Christine Vinciguerra; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Synthesis of GPIb beta with novel transmembrane and cytoplasmic sequences in a Bernard-Soulier patient resulting in GPIb-defective signaling in CHO cells.
Journal of thrombosis and haemostasis : JTH 2006;4(1):217-28.
2005: Philippe Ohlmann; Anita Eckly; Pierre Mangin; François Lanza; Christian Gachet
Further evidence that fibrillar collagen is unable to promote platelet shape change and aggregation in the absence of secondary agonists.
Journal of thrombosis and haemostasis : JTH 2005;3(9):2119-21.
2005: christelle nonne; Nadège Lenain; Béatrice Hechler; Pierre Mangin; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(6):1293-8.
2005: Valérie Wolff; Boris Aleil; Maurice Giroud; Jean-Louis Lorenzini; Nicolas Meyer; Marie-Louise Wiesel; Jean-Pierre Cazenave; François Lanza
Soluble platelet glycoprotein V is a marker of thrombosis in patients with ischemic stroke.
Stroke; a journal of cerebral circulation 2005;36(3):e17-9.
2004: Catherine Strassel; Sylvie Moog; Marie-Jeanne Baas; Jean-Pierre Cazenave; François Lanza
Biosynthesis of platelet glycoprotein V expressed as a single subunit or in association with GPIb-IX.
European journal of biochemistry / FEBS 2004;271(18):3671-7.
2004: Catherine Strassel; M-C Alessi; Irène Juhan-Vague; Jean-Pierre Cazenave; François Lanza
A 13 base pair deletion in the GPIbbeta gene in a second unrelated Bernard-Soulier family due to slipped mispairing between direct repeats.
Journal of thrombosis and haemostasis : JTH 2004;2(9):1663-5.
2004: Pierre Mangin; Tovo David; Vincent Lavaud; Susan L Cranmer; Inna Pikovski; Shaun P Jackson; Michael C Berndt; Jean-Pierre Cazenave; Christian Gachet; François Lanza
Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha.
Blood 2004;104(2):420-7.
2004: Pierre Mangin; Philippe Ohlmann; Anita Eckly; Jean-Pierre Cazenave; François Lanza; Christian Gachet
The P2Y1 receptor plays an essential role in the platelet shape change induced by collagen when TxA2 formation is prevented.
Journal of thrombosis and haemostasis : JTH 2004;2(6):969-77.
2003: Pierre Mangin; Yuping Yuan; Isaac Goncalves; Anita Eckly; Monique Freund; Jean-Pierre Cazenave; Christian Gachet; Shaun P Jackson; François Lanza
Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA.
The Journal of biological chemistry 2003;278(35):32880-91.
2003: Boris Aleil; Jean-Marie Mossard; Marie-Louise Wiesel; François Lanza; Jean-Pierre Cazenave
Increased plasma levels of soluble platelet glycoprotein V in patients with acute myocardial infarction.
Journal of thrombosis and haemostasis : JTH 2003;1(8):1846-7.
2003: Pierre Mangin; christelle nonne; Anita Eckly; Philippe Ohlmann; Monique Freund; Bernhard Nieswandt; Jean-Pierre Cazenave; Christian Gachet; François Lanza
A PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1.
FEBS letters 2003;542(1-3):53-9.
2003: Christelle Perrault; Pierre Mangin; Martine Santer; Marie-Jeanne Baas; Sylvie Moog; Susan L Cranmer; Inna Pikovski; David Williamson; Shaun P Jackson; Jean-Pierre Cazenave; François Lanza
Role of the intracellular domains of GPIb in controlling the adhesive properties of the platelet GPIb/V/IX complex.
Blood 2003;101(9):3477-84.
2003: Catherine Strassel; Jean-Max Pasquet; Marie-Christine Alessi; Irène Juhan-Vague; Hervé Chambost; Robert Combrié; Paquita Nurden; Marie-Jeanne Bas; Corinne De La Salle; Jean-Pierre Cazenave; François Lanza; Alan T Nurden
A novel missense mutation shows that GPIbbeta has a dual role in controlling the processing and stability of the platelet GPIb-IX adhesion receptor.
Biochemistry 2003;42(15):4452-62.
2002: François Lanza; Corinne De La Salle; Marie-Jeanne Baas; Agnès Schwartz; Bernadette Boval; Jean-Pierre Cazenave; Jacques Caen
A Leu7Pro mutation in the signal peptide of platelet glycoprotein (GP)IX in a case of Bernard-Soulier syndrome abolishes surface expression of the GPIb-V-IX complex.
British journal of haematology 2002;118(1):260-6.
2002: Arnaud Scherberich; Grégory Giannone; Elisabeth Perennou; Kenneth Takeda; Claude Boucheix; Eric Rubinstein; François Lanza; Alain Beretz
FAK-mediated inhibition of vascular smooth muscle cell migration by the tetraspanin CD9.
Thrombosis and haemostasis 2002;87(6):1043-50.
2002: David Williamson; Inna Pikovski; Susan L Cranmer; Pierre Mangin; Nayna Mistry; Teresa Domagala; Sam Chehab; François Lanza; Hatem H Salem; Shaun P Jackson
Interaction between platelet glycoprotein Ibalpha and filamin-1 is essential for glycoprotein Ib/IX receptor anchorage at high shear.
The Journal of biological chemistry 2002;277(3):2151-9.
2001: Christelle Perrault; Sylvie Moog; E Rubinstein; Martine Santer; Marie-Jeanne Baas; Corinne De La Salle; Catherine Ravanat; J Dambach; Monique Freund; S Santoso; Jean-Pierre Cazenave; François Lanza
A novel monoclonal antibody against the extracellular domain of GPIbbeta modulates vWF mediated platelet adhesion.
Thrombosis and haemostasis 2001;86(5):1238-48.
2001: P Ulsemer; Catherine Strassel; Marie-Jeanne Baas; J Salamero; S Chasserot-Golaz; Jean-Pierre Cazenave; Corinne De La Salle; François Lanza
Biosynthesis and intracellular post-translational processing of normal and mutant platelet glycoprotein GPIb-IX.
The Biochemical journal 2001;358(Pt 2):295-303.
2001: Sylvie Moog; Pierre Mangin; Nadège Lenain; Catherine Strassel; Catherine Ravanat; Sandrine Schuhler; Monique Freund; Martine Santer; M Kahn; Bernhard Nieswandt; Christian Gachet; Jean-Pierre Cazenave; François Lanza
Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation.
Blood 2001;98(4):1038-46.
2000: Nayna Mistry; Susan L Cranmer; Yuping Yuan; Pierre Mangin; Sacha M Dopheide; Ian Harper; Simon Giuliano; D E Dunstan; François Lanza; Hatem H Salem; Shaun P Jackson
Cytoskeletal regulation of the platelet glycoprotein Ib/V/IX-von willebrand factor interaction.
Blood 2000;96(10):3480-9.
2000: D Loew; Christelle Perrault; M Morales; Sylvie Moog; Catherine Ravanat; Sandrine Schuhler; Rosaria Arcone; Concetta Pietropaolo; Jean-Pierre Cazenave; Alain Van Dorsselaer; François Lanza
Proteolysis of the exodomain of recombinant protease-activated receptors: prediction of receptor activation or inactivation by MALDI mass spectrometry.
Biochemistry 2000;39(35):10812-22.
2000: P Ulsemer; François Lanza; Marie-Jeanne Baas; A Schwartz; Catherine Ravanat; M E Briquel; Susan L Cranmer; S Jackson; Jean-Pierre Cazenave; Corinne De La Salle
Role of the leucine-rich domain of platelet GPIbalpha in correct post-translational processing--the Nancy I Bernard-Soulier mutation expressed on CHO cells.
Thrombosis and haemostasis 2000;84(1):104-11.
2000: Suhasini Kulkarni; Sacha M Dopheide; Cindy L Yap; C Ravanat; M Freund; Pierre Mangin; K A Heel; A Street; Ian Harper; François Lanza; Shaun P Jackson
A revised model of platelet aggregation.
The Journal of clinical investigation 2000;105(6):783-91.
2000: Catherine Ravanat; Monique Freund; Pierre Mangin; David Azorsa; C Schwartz; Sylvie Moog; Sandrine Schuhler; J Dambach; Jean-Pierre Cazenave; François Lanza
GPV is a marker of in vivo platelet activation--study in a rat thrombosis model.
Thrombosis and haemostasis 2000;83(2):327-33.
1999: Yuping Yuan; Suhasini Kulkarni; P Ulsemer; Susan L Cranmer; Cindy L Yap; Warwick S Nesbitt; Ian Harper; Nayna Mistry; Sacha M Dopheide; Sascha C Hughan; David Williamson; Corinne De La Salle; Hatem H Salem; François Lanza; Shaun P Jackson
The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells.
The Journal of biological chemistry 1999;274(51):36241-51.
1999: David Azorsa; Sylvie Moog; Jean-Pierre Cazenave; François Lanza
A general approach to the generation of monoclonal antibodies against members of the tetraspanin superfamily using recombinant GST fusion proteins.
Journal of immunological methods 1999;229(1-2):35-48.
1999: Susan L Cranmer; P Ulsemer; Brian M Cooke; Hatem H Salem; Corinne De La Salle; François Lanza; Shaun P Jackson
Glycoprotein (GP) Ib-IX-transfected cells roll on a von Willebrand factor matrix under flow. Importance of the GPib/actin-binding protein (ABP-280) interaction in maintaining adhesion under high shear.
The Journal of biological chemistry 1999;274(10):6097-106.
1999: David Azorsa; Sylvie Moog; Catherine Ravanat; Sandrine Schuhler; G Folléa; Jean-Pierre Cazenave; François Lanza
Measurement of GPV released by activated platelets using a sensitive immunocapture ELISA--its use to follow platelet storage in transfusion.
Thrombosis and haemostasis 1999;81(1):131-8.
1998: Arnaud Scherberich; Sylvie Moog; G Haan-Archipoff; David Azorsa; François Lanza; Alain Beretz
Tetraspanin CD9 is associated with very late-acting integrins in human vascular smooth muscle cells and modulates collagen matrix reorganization.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(11):1691-7.
1997: Catherine Ravanat; M Morales; David Azorsa; Sylvie Moog; Sandrine Schuhler; P Grunert; D Loew; Alain Van Dorsselaer; Jean-Pierre Cazenave; François Lanza
Gene cloning of rat and mouse platelet glycoprotein V: identification of megakaryocyte-specific promoters and demonstration of functional thrombin cleavage.
Blood 1997;89(9):3253-62.
1994: W C Kouns; B Steiner; T J Kunicki; Sylvie Moog; J Jutzi; Lisa K Jennings; Jean-Pierre Cazenave; François Lanza
Activation of the fibrinogen binding site on platelets isolated from a patient with the Strasbourg I variant of Glanzmann's thrombasthenia.
Blood 1994;84(4):1108-15.