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Douglas Lappi

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Disorders

Procedures

Immunohistochemistry

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Publications

TOP 3
Jeffrey W Allen; Patrick W Mantyh; Kjersti A Horais; Nicolle A Tozier; Scott D Rogers; Joseph R Ghilardi; Dasa Cizkova; Marjorie R Grafe; Phillip Richter; Douglas A Lappi; Tony L Yaksh
Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs.
Douglas A Lappi; Ronald G Wiley
Immunotoxins and neuropeptide-toxin conjugates experimental applications.
Robert P Yezierski; Chen-Guang Yu; Patrick W Mantyh; Charles Vierck Jr; Douglas A Lappi
Spinal neurons involved in the generation of at-level pain following spinal injury in the rat.

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All Publications

2006: Jeffrey W Allen; Patrick W Mantyh; Kjersti A Horais; Nicolle A Tozier; Scott D Rogers; Joseph R Ghilardi; Dasa Cizkova; Marjorie R Grafe; Phillip Richter; Douglas A Lappi; Tony L Yaksh
Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs.
Toxicological sciences : an official journal of the Society of Toxicology 2006;91(1):286-98.
2004: Douglas A Lappi; Ronald G Wiley
Immunotoxins and neuropeptide-toxin conjugates experimental applications.
Mini reviews in medicinal chemistry 2004;4(5):585-95.
2004: Robert P Yezierski; Chen-Guang Yu; Patrick W Mantyh; Charles Vierck Jr; Douglas A Lappi
Spinal neurons involved in the generation of at-level pain following spinal injury in the rat.
Neuroscience letters 2004;361(1-3):232-6.
2003: Ronald G Wiley; M B Harrison; Allan Levey; Douglas A Lappi
Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter.
Cellular and molecular neurobiology 2003;23(4-5):839-50.
2003: Ronald G Wiley; Douglas A Lappi
Targeted toxins in pain.
Advanced drug delivery reviews 2003;55(8):1043-54.
2000: Douglas A Lappi; Ronald G Wiley
Entering through the doors of perception: characterization of a highly selective Substance P receptor-targeted toxin.
Neuropeptides 2000;34(5):323-8.
1999: Ronald G Wiley; Douglas A Lappi
Targeting neurokinin-1 receptor-expressing neurons with [Sar9,Met(O2)11 substance P-saporin.
Neuroscience letters 1999;277(1):1-4.
1999: CC Wrenn; Douglas A Lappi; Ronald G Wiley
Threshold relationship between lesion extent of the cholinergic basal forebrain in the rat and working memory impairment in the radial maze.
Brain research 1999;847(2):284-98.
1999: ML Nichols; BJ Allen; Scott D Rogers; Joseph R Ghilardi; Prisca Honore; Nancy M Luger; MP Finke; J Li; Douglas A Lappi; Donald A Simone; Patrick W Mantyh
Transmission of chronic nociception by spinal neurons expressing the substance P receptor.
Science (New York, N.Y.) 1999;286(5444):1558-61.
1998: Z J Zhang; Douglas A Lappi; CC Wrenn; Teresa A Milner; Ronald G Wiley
Selective lesion of the cholinergic basal forebrain causes a loss of cortical neuropeptide Y and somatostatin neurons.
Brain research 1998;800(2):198-206.
1998: William W Blessing; Douglas A Lappi; Ronald G Wiley
Destruction of locus coeruleus neuronal perikarya after injection of anti-dopamine-B-hydroxylase immunotoxin into the olfactory bulb of the rat.
Neuroscience letters 1998;243(1-3):85-8.
1997: Patrick W Mantyh; Scott D Rogers; Prisca Honore; BJ Allen; Joseph R Ghilardi; J Li; Randy S Daughters; Douglas A Lappi; Ronald G Wiley; Donald A Simone
Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor.
Science (New York, N.Y.) 1997;278(5336):275-9.
1997: Ronald G Wiley; Douglas A Lappi
Destruction of neurokinin-1 receptor expressing cells in vitro and in vivo using substance P-saporin in rats.
Neuroscience letters 1997;230(2):97-100.
1997: T Ohtake; Stephan Heckers; Ronald G Wiley; Douglas A Lappi; Marek-Marsel Mesulam; Changiz Geula
Retrograde degeneration and colchicine protection of basal forebrain cholinergic neurons following hippocampal injections of an immunotoxin against the P75 nerve growth factor receptor.
Neuroscience 1997;78(1):123-33.
1996: CC Wrenn; Matthew J Picklo; Douglas A Lappi; David Robertson; Ronald G Wiley
Central noradrenergic lesioning using anti-DBH-saporin: anatomical findings.
Brain research 1996;740(1-2):175-84.
1995: Matthew J Picklo; Ronald G Wiley; S Lonce; Douglas A Lappi; David Robertson
Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats.
The Journal of pharmacology and experimental therapeutics 1995;275(2):1003-10.
1994: Matthew J Picklo; Ronald G Wiley; Douglas A Lappi; David Robertson
Noradrenergic lesioning with an anti-dopamine beta-hydroxylase immunotoxin.
Brain research 1994;666(2):195-200.