Raynald Laprade

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Lebel Geneviève; Vachon Vincent; Préfontaine Gabrielle; Girard Frédéric; Masson Luke; Juteau Marc; Bah Aliou; Larouche Geneviève; Vincent Charles; Laprade Raynald; Schwartz Jean-Louis
Mutations in domain I interhelical loops affect the rate of pore formation by the Bacillus thuringiensis Cry1Aa toxin in insect midgut brush border membrane vesicles.
Girard Frédéric; Vachon Vincent; Lebel Geneviève; Préfontaine Gabrielle; Schwartz Jean-Louis; Masson Luke; Laprade Raynald
Chemical modification of Bacillus thuringiensis Cry1Aa toxin single-cysteine mutants reveals the importance of domain I structural elements in the mechanism of pore formation.
Girard Frédéric; Vachon Vincent; Préfontaine Gabrielle; Marceau Lucie; Schwartz Jean-Louis; Masson Luke; Laprade Raynald
Helix alpha 4 of the Bacillus thuringiensis Cry1Aa toxin plays a critical role in the postbinding steps of pore formation.

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2009: Lebel Geneviève; Vachon Vincent; Préfontaine Gabrielle; Girard Frédéric; Masson Luke; Juteau Marc; Bah Aliou; Larouche Geneviève; Vincent Charles; Laprade Raynald; Schwartz Jean-Louis
Mutations in domain I interhelical loops affect the rate of pore formation by the Bacillus thuringiensis Cry1Aa toxin in insect midgut brush border membrane vesicles.
Applied and environmental microbiology 2009;75(12):3842-50.
2009: Girard Frédéric; Vachon Vincent; Lebel Geneviève; Préfontaine Gabrielle; Schwartz Jean-Louis; Masson Luke; Laprade Raynald
Chemical modification of Bacillus thuringiensis Cry1Aa toxin single-cysteine mutants reveals the importance of domain I structural elements in the mechanism of pore formation.
Biochimica et biophysica acta 2009;1788(2):575-80.
2009: Girard Frédéric; Vachon Vincent; Préfontaine Gabrielle; Marceau Lucie; Schwartz Jean-Louis; Masson Luke; Laprade Raynald
Helix alpha 4 of the Bacillus thuringiensis Cry1Aa toxin plays a critical role in the postbinding steps of pore formation.
Applied and environmental microbiology 2009;75(2):359-65.
2009: Belleannée C; Da Silva N; Shum W W C; Marsolais M; Laprade R; Brown D; Breton S
Segmental expression of the bradykinin type 2 receptor in rat efferent ducts and epididymis and its role in the regulation of aquaporin 9.
Biology of reproduction 2009;80(1):134-43.
2008: Girard Frédéric; Vachon Vincent; Préfontaine Gabrielle; Marceau Lucie; Su Yanhui; Larouche Geneviève; Vincent Charles; Schwartz Jean-Louis; Masson Luke; Laprade Raynald
Cysteine scanning mutagenesis of alpha4, a putative pore-lining helix of the Bacillus thuringiensis insecticidal toxin Cry1Aa.
Applied and environmental microbiology 2008;74(9):2565-72.
2008: Laflamme Eric; Badia Antonella; Lafleur Michel; Schwartz Jean-Louis; Laprade Raynald
Atomic force microscopy imaging of Bacillus thuringiensis Cry1 toxins interacting with insect midgut apical membranes.
The Journal of membrane biology 2008;222(3):127-39.
2008: Pietrement Christine; Da Silva Nicolas; Silberstein Claudia; James Marianne; Marsolais Mireille; Van Hoek Alfred; Brown Dennis; Pastor-Soler Nuria; Ameen Nadia; Laprade Raynald; Ramesh Vijaya; Breton Sylvie
Role of NHERF1, cystic fibrosis transmembrane conductance regulator, and cAMP in the regulation of aquaporin 9.
The Journal of biological chemistry 2008;283(5):2986-96.
2007: Fortier Mélanie; Vachon Vincent; Frutos Roger; Schwartz Jean-Louis; Laprade Raynald
Effect of insect larval midgut proteases on the activity of Bacillus thuringiensis Cry toxins.
Applied and environmental microbiology 2007;73(19):6208-13.
2007: Fortier Mélanie; Vachon Vincent; Marceau Lucie; Schwartz Jean-Louis; Laprade Raynald
Kinetics of pore formation by the Bacillus thuringiensis toxin Cry1Ac.
Biochimica et biophysica acta 2007;1768(5):1291-8.
2006: Kirouac Martin; Vachon Vincent; Fortier Mélanie; Trudel Marie-Claude; Berteloot Alfred; Schwartz Jean-Louis; Laprade Raynald
A mechanical force contributes to the "osmotic swelling" of brush-border membrane vesicles.
Biophysical journal 2006;91(9):3301-12.
2006: Vachon Vincent; Schwartz Jean-Louis; Laprade Raynald
Influence of the biophysical and biochemical environment on the kinetics of pore formation by Cry toxins.
Journal of invertebrate pathology 2006;92(3):160-5.
2006: Kirouac Martin; Vachon Vincent; Quievy Delphine; Schwartz Jean-Louis; Laprade Raynald
Protease inhibitors fail to prevent pore formation by the activated Bacillus thuringiensis toxin Cry1Aa in insect brush border membrane vesicles.
Applied and environmental microbiology 2006;72(1):506-15.
2005: Fortier M; Vachon V; Kirouac M; Schwartz J-L; Laprade R
Differential effects of ionic strength, divalent cations and pH on the pore-forming activity of Bacillus thuringiensis insecticidal toxins.
The Journal of membrane biology 2005;208(1):77-87.
2004: Vachon Vincent; Préfontaine Gabrielle; Rang Cécile; Coux Florence; Juteau Marc; Schwartz Jean-Louis; Brousseau Roland; Frutos Roger; Laprade Raynald; Masson Luke
Helix 4 mutants of the Bacillus thuringiensis insecticidal toxin Cry1Aa display altered pore-forming abilities.
Applied and environmental microbiology 2004;70(10):6123-30.
2004: Peyronnet Olivier; Noulin Jean-François; Laprade Raynald; Schwartz Jean-Louis
Patch-clamp study of the apical membrane of the midgut of Manduca sexta larvae: direct demonstration of endogenous channels and effect of a Bacillus thuringiensis toxin.
Journal of insect physiology 2004;50(9):791-803.
2003: Kirouac M; Vachon V; Rivest S; Schwartz J-L; Laprade R
Analysis of the properties of Bacillus thuringiensis insecticidal toxins using a potential-sensitive fluorescent probe.
The Journal of membrane biology 2003;196(1):51-9.
2003: Granger D; Marsolais M; Burry J; Laprade R
Na+/H+ exchangers in the human eccrine sweat duct.
American journal of physiology. Cell physiology 2003;285(5):C1047-58.
2002: Su Yanhui; Qu Hong; Vachon Vincent; Luo Jingchu; Zhang Jie; Laprade Raynald; Zhu Yuxian
The toxicity test and hypothetical model ofBacillus thuringiensis Cry1Aa helix4.
Science in China. Series C, Life sciences / Chinese Academy of Sciences 2002;45(6):561-8.
2002: Peyronnet Olivier; Nieman Brian; Généreux Francis; Vachon Vincent; Laprade Raynald; Schwartz Jean-Louis
Estimation of the radius of the pores formed by the Bacillus thuringiensis Cry1C delta-endotoxin in planar lipid bilayers.
Biochimica et biophysica acta 2002;1567(1-2):113-22.
2002: Granger D; Marsolais M; Burry J; Laprade R
V-type H+-ATPase in the human eccrine sweat duct: immunolocalization and functional demonstration.
American journal of physiology. Cell physiology 2002;282(6):C1454-60.
2002: Vachon Vincent; Préfontaine Gabrielle; Coux Florence; Rang Cécile; Marceau Lucie; Masson Luke; Brousseau Roland; Frutos Roger; Schwartz Jean-Louis; Laprade Raynald
Role of helix 3 in pore formation by the Bacillus thuringiensis insecticidal toxin Cry1Aa.
Biochemistry 2002;41(19):6178-84.
2002: Kirouac Martin; Vachon Vincent; Noël Jean-François; Girard Frédéric; Schwartz Jean-Louis; Laprade Raynald
Amino acid and divalent ion permeability of the pores formed by the Bacillus thuringiensis toxins Cry1Aa and Cry1Ac in insect midgut brush border membrane vesicles.
Biochimica et biophysica acta 2002;1561(2):171-9.
2002: Brochiero Emmanuelle; Wallendorf Bernadette; Gagnon Dominique; Laprade Raynald; Lapointe Jean-Yves
Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel.
American journal of physiology. Renal physiology 2002;282(2):F289-300.
2001: Noulin J F; Brochiero E; Coady M J; Laprade R; Lapointe J Y
Molecular identity and regulation of renal potassium channels.
The Japanese journal of physiology 2001;51(6):631-47.
2001: Guihard G; Laprade R; Schwartz J L
Unfolding affects insect cell permeabilization by Bacillus thuringiensis Cry1C toxin.
Biochimica et biophysica acta 2001;1515(2):110-9.
2001: Peyronnet O; Vachon V; Schwartz J L; Laprade R
Ion channels induced in planar lipid bilayers by the Bacillus thuringiensis toxin Cry1Aa in the presence of gypsy moth (Lymantria dispar) brush border membrane.
The Journal of membrane biology 2001;184(1):45-54.
2001: Tran L B; Vachon V; Schwartz J L; Laprade R
Differential effects of pH on the pore-forming properties of Bacillus thuringiensis insecticidal crystal toxins.
Applied and environmental microbiology 2001;67(10):4488-94.
2001: Coux F; Vachon V; Rang C; Moozar K; Masson L; Royer M; Bes M; Rivest S; Brousseau R; Schwartz J L; Laprade R; Frutos R
Role of interdomain salt bridges in the pore-forming ability of the Bacillus thuringiensis toxins Cry1Aa and Cry1Ac.
The Journal of biological chemistry 2001;276(38):35546-51.
2001: Rang C; Vachon V; Coux F; Carret C; Moar W J; Brousseau R; Schwartz J L; Laprade R; Frutos R
Exchange of domain I from Bacillus thuringiensis Cry1 Toxins Influences protoxin stability and crystal formation.
Current microbiology 2001;43(1):1-6.
2001: Vié V; Van Mau N; Pomarède P; Dance C; Schwartz J L; Laprade R; Frutos R; Rang C; Masson L; Heitz F; Le Grimellec C
Lipid-induced pore formation of the Bacillus thuringiensis Cry1Aa insecticidal toxin.
The Journal of membrane biology 2001;180(3):195-203.
2001: Bagnis C; Marsolais M; Biemesderfer D; Laprade R; Breton S
Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis.
American journal of physiology. Renal physiology 2001;280(3):F426-36.
2001: Brochiero E; Coady M J; Klein H; Laprade R; Lapointe J Y
Activation of an ATP-dependent K(+) conductance in Xenopus oocytes by expression of adenylate kinase cloned from renal proximal tubules.
Biochimica et biophysica acta 2001;1510(1-2):29-42.
2000: Lagana A; Vadnais J; Le P U; Nguyen T N; Laprade R; Nabi I R; Noël J
Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1.
Journal of cell science 2000;113 ( Pt 20)():3649-62.
2000: Peyronnet O; Vachon V; Schwartz J L; Laprade R
Ion channel activity from the midgut brush-border membrane of gypsy moth (Lymantria dispar) larvae.
The Journal of experimental biology 2000;203(Pt 12):1835-44.
2000: Guihard G; Vachon V; Laprade R; Schwartz J L
Kinetic properties of the channels formed by the bacillus thuringiensis insecticidal crystal protein Cry1C in the plasma membrane of Sf9 cells.
The Journal of membrane biology 2000;175(2):115-22.
1999: Noulin J F; Brochiero E; Lapointe J Y; Laprade R
Two types of K(+) channels at the basolateral membrane of proximal tubule: inhibitory effect of taurine.
The American journal of physiology 1999;277(2 Pt 2):F290-7.
1999: Rang C; Vachon V; de Maagd R A; Villalon M; Schwartz J L; Bosch D; Frutos R; Laprade R
Interaction between functional domains of Bacillus thuringiensis insecticidal crystal proteins.
Applied and environmental microbiology 1999;65(7):2918-25.
1999: Guihard G; Falk S; Vachon V; Laprade R; Schwartz J L
Real-time fluorimetric analysis of gramicidin D- and alamethicin-induced K+ efflux from Sf9 and Cf1 insect cells.
Biochemistry 1999;38(19):6164-70.
1998: Villalon M; Vachon V; Brousseau R; Schwartz J L; Laprade R
Video imaging analysis of the plasma membrane permeabilizing effects of Bacillus thuringiensis insecticidal toxins in Sf9 cells.
Biochimica et biophysica acta 1998;1368(1):27-34.
1997: Schwartz J L; Potvin L; Chen X J; Brousseau R; Laprade R; Dean D H
Single-site mutations in the conserved alternating-arginine region affect ionic channels formed by CryIAa, a Bacillus thuringiensis toxin.
Applied and environmental microbiology 1997;63(10):3978-84.
1997: Schwartz J L; Lu Y J; Söhnlein P; Brousseau R; Laprade R; Masson L; Adang M J
Ion channels formed in planar lipid bilayers by Bacillus thuringiensis toxins in the presence of Manduca sexta midgut receptors.
FEBS letters 1997;412(2):270-6.
1997: Peyronnet O; Vachon V; Brousseau R; Baines D; Schwartz J L; Laprade R
Effect of Bacillus thuringiensis toxins on the membrane potential of lepidopteran insect midgut cells.
Applied and environmental microbiology 1997;63(5):1679-84.
1997: Macri P; Breton S; Marsolais M; Lapointe J; Laprade R
Hypertonicity decreases basolateral K+ and Cl- conductances in rabbit proximal convoluted tubule.
The Journal of membrane biology 1997;155(3):229-37.
1996: Breton S; Belachgar F; Marsolais M; Lapointe J Y; Laprade R
Inhibition of basolateral potassium conductance by taurine in the proximal convoluted tubule.
The American journal of physiology 1996;271(5 Pt 2):F1012-9.
1996: Breton S; Marsolais M; Lapointe J Y; Laprade R
Cell volume increases of physiologic amplitude activate basolateral K and CI conductances in the rabbit proximal convoluted tubule.
Journal of the American Society of Nephrology : JASN 1996;7(10):2072-87.
1996: Laprade R; Noulin J F; Lapointe J Y
Volume regulation and ion transport in renal cells.
Current opinion in nephrology and hypertension 1996;5(5):417-21.
1996: Dahan D; Srikumar R; Laprade R; Coulton J W
Purification and refolding of recombinant Haemophilus influenzae type b porin produced in Bacillus subtilis.
FEBS letters 1996;392(3):304-8.
1995: Vachon V; Paradis M J; Marsolais M; Schwartz J L; Laprade R
Ionic permeabilities induced by Bacillus thuringiensis in Sf9 cells.
The Journal of membrane biology 1995;148(1):57-63.
1995: Vachon V; Paradis M J; Marsolais M; Schwartz J L; Laprade R
Endogenous K+/H+ exchange activity in the Sf9 insect cell line.
Biochemistry 1995;34(46):15157-64.
1995: Breton S; Marsolais M; Laprade R
Hypotonicity increases basolateral taurine permeability in rabbit proximal convoluted tubule.
The American journal of physiology 1995;268(4 Pt 2):F595-603.
1995: Vachon V; Delisle M C; Giroux S; Laprade R; Béliveau R
Factors affecting the stability of the renal sodium/phosphate symporter during its solubilization and reconstitution.
The international journal of biochemistry & cell biology 1995;27(3):311-8.
1995: Beck J S; Marsolais M; Nöel J; Breton S; Laprade R
Dibutyryl cyclic adenosine monophosphate stimulates the sodium pump in rabbit renal cortical tubules.
Renal physiology and biochemistry 1995;18(1):21-6.
1994: Beck J S; Laprade R; Lapointe J Y
Coupling between transepithelial Na transport and basolateral K conductance in renal proximal tubule.
The American journal of physiology 1994;266(4 Pt 2):F517-27.
1994: Breton S; Beck J S; Laprade R
cAMP stimulates proximal convoluted tubule Na(+)-K(+)-ATPase activity.
The American journal of physiology 1994;266(3 Pt 2):F400-10.
1994: Dahan D; Vachon V; Laprade R; Coulton J W
Voltage gating of porins from Haemophilus influenzae type b.
Biochimica et biophysica acta 1994;1189(2):204-11.
1993: Noël J; Fleser A; Bellemare F; Thiéry G; Laprade R; Burckhardt G; Vinay P
Effect of cholate on H(+)-ATPase and other proteins of dog renal brush-border membrane.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1993;71(7-8):390-400.
1993: Hurst A M; Beck J S; Laprade R; Lapointe J Y
Na+ pump inhibition downregulates an ATP-sensitive K+ channel in rabbit proximal convoluted tubule.
The American journal of physiology 1993;264(4 Pt 2):F760-4.
1993: Noël J; Vinay P; Tejedor A; Fleser A; Laprade R
Metabolic cost of bafilomycin-sensitive H+ pump in intact dog, rabbit, and hamster proximal tubules.
The American journal of physiology 1993;264(4 Pt 2):F655-61.
1993: Beck J S; Hurst A M; Lapointe J Y; Laprade R
Regulation of basolateral K channels in proximal tubule studied during continuous microperfusion.
The American journal of physiology 1993;264(3 Pt 2):F496-501.
1993: Macri P; Breton S; Beck J S; Cardinal J; Laprade R
Basolateral K+, Cl-, and HCO3- conductances and cell volume regulation in rabbit PCT.
The American journal of physiology 1993;264(2 Pt 2):F365-76.
1993: Beck J; Laprade R
Evidence against a proton pump in rabbit proximal convoluted tubule.
The American journal of physiology 1993;264(1 Pt 2):F175-80.
1992: Breton S; Beck J S; Cardinal J; Giebisch G; Laprade R
Involvement and source of calcium in volume regulatory decrease of collapsed proximal convoluted tubule.
The American journal of physiology 1992;263(4 Pt 2):F656-64.
1992: Beck J S; Breton S; Giebisch G; Laprade R
Potassium conductance regulation by pH during volume regulation in rabbit proximal convoluted tubules.
The American journal of physiology 1992;263(3 Pt 2):F453-8.
1992: Noël J; Tejedor A; Vinay P; Laprade R
Substrate-induced modulation of ATP turnover in dog and rabbit proximal tubules.
The Journal of membrane biology 1992;128(3):205-18.
1992: Delisle M C; Vachon V; Giroux S; Potier M; Laprade R; Béliveau R
Molecular size of the renal sodium/phosphate symporter in native and reconstituted systems.
Biochimica et biophysica acta 1992;1104(1):132-6.
1991: Beck J S; Breton S; Mairbäurl H; Laprade R; Giebisch G
Relationship between sodium transport and intracellular ATP in isolated perfused rabbit proximal convoluted tubule.
The American journal of physiology 1991;261(4 Pt 2):F634-9.
1991: Vachon V; Delisle M C; Laprade R; Béliveau R
Reconstitution of the renal brush-border membrane sodium/phosphate co-transporter.
The Biochemical journal 1991;278 ( Pt 2)():543-8.
1991: Beck J S; Breton S; Laprade R; Giebisch G
Volume regulation and intracellular calcium in the rabbit proximal convoluted tubule.
The American journal of physiology 1991;260(6 Pt 2):F861-7.
1991: Laprade R; Lapointe J Y; Breton S; Duplain M; Cardinal J
Intracellular potassium activity in mammalian proximal tubule: effect of perturbations in transepithelial sodium transport.
The Journal of membrane biology 1991;121(3):249-59.
1991: Sheppard J D; Jumarie C; Cooper D G; Laprade R
Ionic channels induced by surfactin in planar lipid bilayer membranes.
Biochimica et biophysica acta 1991;1064(1):13-23.
1991: Vachon V; Pouliot J F; Laprade R; Béliveau R
Fractionation of renal brush border membrane proteins with Triton X-114 phase partitioning.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1991;69(2-3):206-11.
1989: Noël J; Tejedor A; Vinay P; Laprade R
Fluorescence measurement of intracellular pH on proximal tubule suspensions. The need for a BCECF sink.
Renal physiology and biochemistry 1989;12(5-6):371-87.
1986: Vachon V; Laprade R; Coulton J W
Properties of the porin of Haemophilus influenzae type b in planar lipid bilayer membranes.
Biochimica et biophysica acta 1986;861(1):74-82.
1986: Lapointe J Y; Laprade R; Cardinal J
Characterization of the apical membrane ionic permeability of the rabbit proximal convoluted tubule.
The American journal of physiology 1986;250(2 Pt 2):F339-47.
1984: Lapointe J Y; Laprade R; Cardinal J
Transepithelial and cell membrane electrical resistances of the rabbit proximal convoluted tubule.
The American journal of physiology 1984;247(4 Pt 2):F637-49.
1984: Laprade R; Grenier F; Pagé-Dansereau M; Dansereau J
Carrier-mediated ion transport in lipid bilayer membranes.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire 1984;62(8):738-51.
1984: Cardinal J; Lapointe J Y; Laprade R
Luminal and peritubular ionic substitutions and intracellular potential of the rabbit proximal convoluted tubule.
The American journal of physiology 1984;247(2 Pt 2):F352-64.
1983: Laprade R; Cardinal J
Liquid junctions and isolated proximal tubule transepithelial potentials.
The American journal of physiology 1983;244(3):F304-19.
1982: Gagnon J; Ouimet D; Nguyen H; Laprade R; Le Grimellec C; Carrière S; Cardinal J
Cell volume regulation in the proximal convoluted tubule.
The American journal of physiology 1982;243(4):F408-15.
1982: Lapointe J Y; Laprade R
Kinetics of carrier-mediated ion transport in two new types of solvent-free lipid bilayers.
Biophysical journal 1982;39(2):141-50.
1982: Laprade R; Lapointe J Y
[Comparison of the kinetics of ionophore-induced ion transport in conventional and solventless membranes]
Revue canadienne de biologie expérimentale 1982;41(1):13-22.
1982: Laprade R; Grenier F; Lapointe J Y; Asselin S
Effects of variation of ion and methylation of carrier on the rate constants of macrotetralide-mediated ion transport in lipid bilayers.
The Journal of membrane biology 1982;68(3):191-206.

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Raynald Laprade

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