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Filip Lardon

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Chemicals & Drugs

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Papillomaviridae

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Christophe Deben; Marc Baay; Carolien Boeckx; Filip Lardon; Patrick Pauwels; Marc Peeters; An Wouters; Karen Zwaenepoel; Vanessa Deschoolmeester
Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples.
An Wouters; Carolien Boeckx; Marc Peeters; Danielle Van den Weyngaert; Jan B Vermorken; Filip Lardon
The intriguing interplay between therapies targeting the epidermal growth factor receptor, the hypoxic microenvironment and hypoxia-inducible factors.
Veronique Verhoeven; Paul Van Royen; John-Paul Bogers; Filip Lardon; Amin Makar; Marc Peeters; Nathalie Renard; Marc Baay
Probiotics enhance the clearance of human papillomavirus-related cervical lesions: a prospective controlled pilot study.

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All Publications

2013: Christophe Deben; Marc Baay; Carolien Boeckx; Filip Lardon; Patrick Pauwels; Marc Peeters; An Wouters; Karen Zwaenepoel; Vanessa Deschoolmeester
Expression analysis on archival material revisited: isolation and quantification of RNA extracted from FFPE samples.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2013;22(1):59-64.
2013: An Wouters; Carolien Boeckx; Marc Peeters; Danielle Van den Weyngaert; Jan B Vermorken; Filip Lardon
The intriguing interplay between therapies targeting the epidermal growth factor receptor, the hypoxic microenvironment and hypoxia-inducible factors.
Current pharmaceutical design 2013;19(5):907-17.
2013: Veronique Verhoeven; Paul Van Royen; John-Paul Bogers; Filip Lardon; Amin Makar; Marc Peeters; Nathalie Renard; Marc Baay
Probiotics enhance the clearance of human papillomavirus-related cervical lesions: a prospective controlled pilot study.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2013;22(1):46-51.
2012: Willem A Den Hengst; Gunther Guetens; Jeroen M H Hendriks; Karel Heytens; Filip Lardon; Tom Van Hoof; Gert de Boeck; Paul E Y Van Schil
Selective pulmonary artery perfusion with melphalan is equal to isolated lung perfusion but superior to intravenous melphalan for the treatment of sarcoma lung metastases in a rodent model.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2012;42(2):341-7; discussion 347.
2012: Ridha Limame; Bea Pauwels; Olivier De Wever; Erik Fransen; Filip Lardon; Marc Peeters; An Wouters; Patrick Pauwels
Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays.
PloS one 2012;7(10):e46536.
2011: Carolien Boeckx; Vanessa Deschoolmeester; Filip Lardon; Krzysztof Lukaszuk; Bea Pauwels; Patrick Pauwels; Marc Peeters; Pol Specenier; Jan B Vermorken; An Wouters; Marc F D Baay
Expression analysis on archival material: comparison of 5 commercially available RNA isolation kits for FFPE material.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2011;20(4):203-11.
2011: An Wouters; Bea Pauwels; Hilde A J Lambrechts; Greet G O Pattyn; Johan Ides; Marc Baay; Paul Meijnders; Marc Peeters; Jan B Vermorken; Filip Lardon
Retention of the in vitro radiosensitizing potential of gemcitabine under anoxic conditions, in p53 wild-type and p53-deficient non-small-cell lung carcinoma cells.
International journal of radiation oncology, biology, physics 2011;80(2):558-66.
2011: Marc F D Baay; Katrien Francois; Filip Lardon; Paul Van Royen; Patrick Pauwels; Jan B Vermorken; Marc Peeters; Veronique Verhoeven
The presence of Y chromosomal deoxyribonucleic acid in the female vaginal swab: possible implications for human papillomavirus testing.
Cancer epidemiology 2011;35(1):101-3.
2010: V Deschoolmeester; C Boeckx; Marc Baay; Joost Weyler; W Wuyts; Eric Van Marck; M Peeters; Filip Lardon; Jan B Vermorken
KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis.
British journal of cancer 2010;103(10):1627-36.
2010: Veronique Verhoeven; Marc Baay; Pieter E Baay; Filip Lardon; Paul Van Royen; Jan B Vermorken
Everything you always wanted to know about HPV (but could not ask your doctor).
Patient education and counseling 2010;81(1):101-5.
2010: Bea Pauwels; An Wouters; Marc Peeters; Jan B Vermorken; Filip Lardon
Role of cell cycle perturbations in the combination therapy of chemotherapeutic agents and radiation.
Future oncology (London, England) 2010;6(9):1485-96.
2010: An Wouters; Bea Pauwels; Hilde A J Lambrechts; Greet G O Pattyn; Johan Ides; Marc Baay; Paul Meijnders; Filip Lardon; Jan B Vermorken
Counting clonogenic assays from normoxic and anoxic irradiation experiments manually or by using densitometric software.
Physics in medicine and biology 2010;55(7):N167-78.
2010: An Wouters; Bea Pauwels; Filip Lardon; Greet G O Pattyn; Hilde A J Lambrechts; Marc Baay; Paul Meijnders; Jan B Vermorken
In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells.
BMC cancer 2010;10():441.
2010: Vanessa Deschoolmeester; Marc Baay; Pol Specenier; Filip Lardon; Jan B Vermorken
A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy.
The oncologist 2010;15(7):699-731.
2010: Vanessa Deschoolmeester; Marc Baay; Eric Van Marck; Joost Weyler; Peter Vermeulen; Filip Lardon; Jan B Vermorken
Tumor infiltrating lymphocytes: an intriguing player in the survival of colorectal cancer patients.
BMC immunology 2010;11():19.
2010: Vanessa Deschoolmeester; Veerle Van Marck; Marc Baay; Christine Weyn; Peter Vermeulen; Eric Van Marck; Filip Lardon; Veronique Fontaine; Jan B Vermorken
Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer.
BMC cancer 2010;10():117.
2009: An Wouters; Bea Pauwels; Hilde A J Lambrechts; Greet G O Pattyn; Johan Ides; Marc Baay; Paul Meijnders; Sylvia Dewilde; Jan B Vermorken; Filip Lardon
Chemoradiation interactions under reduced oxygen conditions: Cellular characteristics of an in vitro model.
Cancer letters 2009;286(2):180-8.
2009: Bea Pauwels; Jan B Vermorken; A Wouters; J Ides; S Van Laere; Hilde A J Lambrechts; Greet G O Pattyn; Katrien Vermeulen; P Meijnders; Filip Lardon
The role of apoptotic cell death in the radiosensitising effect of gemcitabine.
British journal of cancer 2009;101(4):628-36.
2008: Vanessa Deschoolmeester; Nancy Van Damme; Marc Baay; Kathleen Claes; Eric Van Marck; Filip J Baert; Wim Wuyts; Marc Cabooter; Joost Weyler; Peter Vermeulen; Filip Lardon; Jan B Vermorken; Marc Peeters
Microsatellite instability in sporadic colon carcinomas has no independent prognostic value in a Belgian study population.
European journal of cancer (Oxford, England : 1990) 2008;44(15):2288-95.
2008: Cindy Simoens; Bea Pauwels; Jan B Vermorken; Greet G O Pattyn; Hilde A J Lambrechts; Fabienne Breillout; Filip Lardon
Further mechanistic unravelling of the influence of the cell cycle effects on the radiosensitising mechanism of vinflunine, in vitro.
Cancer chemotherapy and pharmacology 2008;62(2):183-93.
2008: Vanessa Deschoolmeester; Marc Baay; Wim Wuyts; Eric Van Marck; Nancy Van Damme; Peter Vermeulen; Krzysztof Lukaszuk; Filip Lardon; Jan B Vermorken
Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.
The Journal of molecular diagnostics : JMD 2008;10(2):154-9.
2008: Cindy Simoens; Filip Lardon; Bea Pauwels; Christel M J de Pooter; Hilde A J Lambrechts; Greet G O Pattyn; Fabienne Breillout; Jan B Vermorken
Comparative study of the radiosensitizing and cell cycle effects of vinflunine and vinorelbine, in vitro.
BMC cancer 2008;8():65.
2007: An Wouters; Bea Pauwels; Filip Lardon; Jan B Vermorken
Review: implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions.
The oncologist 2007;12(6):690-712.
2006: Bea Pauwels; Annelies E C Korst; Hilde A J Lambrechts; Greet G O Pattyn; Christel M J de Pooter; Filip Lardon; Jan B Vermorken
The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro.
Cancer chemotherapy and pharmacology 2006;58(2):219-28.
2006: Cindy Simoens; Jan B Vermorken; Annelies E C Korst; Bea Pauwels; Christel M J de Pooter; Greet G O Pattyn; Hilde A J Lambrechts; Fabienne Breillout; Filip Lardon
Cell cycle effects of vinflunine, the most recent promising Vinca alkaloid, and its interaction with radiation, in vitro.
Cancer chemotherapy and pharmacology 2006;58(2):210-8.
2006: Bea Pauwels; Annelies E C Korst; Greet G O Pattyn; Hilde A J Lambrechts; Juliette A E Kamphuis; Christel M J de Pooter; Godefridus J Peters; Filip Lardon; Jan B Vermorken
The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines.
BMC cancer 2006;6():142.
2006: Vanessa Deschoolmeester; Marc Baay; Wim Wuyts; Eric Van Marck; Paul A Pelckmans; Filip Lardon; Jan B Vermorken
Comparison of three commonly used PCR-based techniques to analyze MSI status in sporadic colorectal cancer.
Journal of clinical laboratory analysis 2006;20(2):52-61.
2005: Marc Baay; W A A Tjalma; Hilde A J Lambrechts; Greet G O Pattyn; Filip Lardon; Joost Weyler; Paul Van Royen; Eric A Van Marck; Jan B Vermorken
Combined Pap and HPV testing in primary screening for cervical abnormalities: should HPV detection be delayed until age 35?
European journal of cancer (Oxford, England : 1990) 2005;41(17):2704-8.
2005: Bea Pauwels; Annelies E C Korst; Veronique Andriessen; Marc Baay; Greet G O Pattyn; Hilde A J Lambrechts; Christel M J De Pooter; Filip Lardon; Jan B Vermorken
Unraveling the mechanism of radiosensitization by gemcitabine: the role of TP53.
Radiation research 2005;164(5):642-50.
2005: Bea Pauwels; Annelies E C Korst; Filip Lardon; Jan B Vermorken
Combined modality therapy of gemcitabine and radiation.
The oncologist 2005;10(1):34-51.
2004: Veronique Verhoeven; Marc Baay; Joost Weyler; Dirk Avonts; Filip Lardon; Paul Van Royen; Jan B Vermorken
Concomitant Chlamydia trachomatis and human papilloma virus infection cannot be attributed solely to sexual behaviour.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2004;23(9):735-7.
2004: Marc Baay; Filip Lardon; J B Vermorken; Veronique Verhoeven; Dirk Avonts; Paul Van Royen; Kristien Wouters; Pierre Van Damme; E Van Marck
HPV in cervix and vagina.
Sexually transmitted infections 2004;80(3):249-50.
2004: Marc Baay; Evelien Smits; W A A Tjalma; Filip Lardon; Joost Weyler; Paul Van Royen; Eric A Van Marck; Jan B Vermorken
Can cervical cancer screening be stopped at 50? The prevalence of HPV in elderly women.
International journal of cancer. Journal international du cancer 2004;108(2):258-61.
2004: Marc Baay; Veronique Verhoeven; Kristien Wouters; Filip Lardon; Pierre Van Damme; Dirk Avonts; Eric Van Marck; Paul Van Royen; Jan B Vermorken
The prevalence of the human papillomavirus in cervix and vagina in low-risk and high-risk populations.
Scandinavian journal of infectious diseases 2004;36(6-7):456-9.
2003: C Simoens; Annelies E C Korst; Christel M J de Pooter; Hilde A J Lambrechts; Greet G O Pattyn; G T Faircloth; Filip Lardon; Jan B Vermorken
In vitro interaction between ecteinascidin 743 (ET-743) and radiation, in relation to its cell cycle effects.
British journal of cancer 2003;89(12):2305-11.
2003: Bea Pauwels; Annelies E C Korst; Greet G O Pattyn; Hilde A J Lambrechts; Dirk R Van Bockstaele; Katrien Vermeulen; Marc Lenjou; Christel M J de Pooter; Jan B Vermorken; Filip Lardon
Cell cycle effect of gemcitabine and its role in the radiosensitizing mechanism in vitro.
International journal of radiation oncology, biology, physics 2003;57(4):1075-83.
2003: Bea Pauwels; Annelies E C Korst; Christel M J de Pooter; Hilde A J Lambrechts; Greet G O Pattyn; Filip Lardon; Jan B Vermorken
The radiosensitising effect of gemcitabine and the influence of the rescue agent amifostine in vitro.
European journal of cancer (Oxford, England : 1990) 2003;39(6):838-46.
2003: Bea Pauwels; Annelies E C Korst; Christel M J de Pooter; Greet G O Pattyn; Hilde A J Lambrechts; Marc Baay; Filip Lardon; Jan B Vermorken
Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies.
Cancer chemotherapy and pharmacology 2003;51(3):221-6.
2002: Peter Ponsaerts; Glenn A Van den Bosch; Nathalie Cools; Ann Van Driessche; Griet Nijs; Marc Lenjou; Filip Lardon; Christine Van Broeckhoven; Dirk R Van Bockstaele; Zwi N Berneman; V F I Van Tendeloo
Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):1669-75.
2002: Peter Ponsaerts; V F I Van Tendeloo; Nathalie Cools; Ann Van Driessche; Filip Lardon; Griet Nijs; Marc Lenjou; Gerhard Mertens; Christine Van Broeckhoven; Dirk R Van Bockstaele; Zwi N Berneman
mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation.
Leukemia 2002;16(7):1324-30.
2001: V F I Van Tendeloo; Peter Ponsaerts; Filip Lardon; Griet Nijs; Marc Lenjou; Christine Van Broeckhoven; Dirk R Van Bockstaele; Zwi N Berneman
Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells.
Blood 2001;98(1):49-56.
2001: Marc Baay; W A A Tjalma; Joost Weyler; Greet G O Pattyn; Hilde A J Lambrechts; GC Goovaerts; M Baekelandt; Philippe Buytaert; Eric A Van Marck; Filip Lardon; Jan B Vermorken
Prevalence of human papillomavirus in elderly women with cervical cancer.
Gynecologic and obstetric investigation 2001;52(4):248-51.
2001: Marc Baay; W A A Tjalma; Joost Weyler; GC Goovaerts; Philippe Buytaert; Eric A Van Marck; Filip Lardon; Jan B Vermorken
Human papillomavirus infection in the female population of Antwerp, Belgium: prevalence in healthy women, women with premalignant lesions and cervical cancer.
European journal of gynaecological oncology 2001;22(3):204-8.
1999: Peter B Vermeulen; Gert G Van den Eynden; Philippe Huget; GC Goovaerts; Joost Weyler; Filip Lardon; Eric Van Marck; G Hubens; Luc Y Dirix
Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer.
British journal of cancer 1999;79(2):316-22.
1998: SF Weekx; Dirk R Van Bockstaele; Jean Plum; Adriaan C Moulijn; Inez E Rodrigus; Filip Lardon; Magda De Smedt; Griet Nijs; Marc Lenjou; P Loquet; Zwi N Berneman; Hans-Willem Snoeck
CD34++ CD38- and CD34+ CD38+ human hematopoietic progenitors from fetal liver, cord blood, and adult bone marrow respond differently to hematopoietic cytokines depending on the ontogenic source.
Experimental hematology 1998;26(11):1034-42.
1998: Roel Willems; Dirk R Van Bockstaele; Filip Lardon; Marc Lenjou; Griet Nijs; Hans-Willem Snoeck; Zwi N Berneman; Herman Slegers
Decrease in nucleoside diphosphate kinase (NDPK/nm23) expression during hematopoietic maturation.
The Journal of biological chemistry 1998;273(22):13663-8.
1998: V F I Van Tendeloo; Hans-Willem Snoeck; Filip Lardon; Guido Vanham; Griet Nijs; Marc Lenjou; L Hendriks; Christine Van Broeckhoven; Adriaan C Moulijn; Inez E Rodrigus; P Verdonk; Dirk R Van Bockstaele; Zwi N Berneman
Nonviral transfection of distinct types of human dendritic cells: high-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells.
Gene therapy 1998;5(5):700-7.
1997: Filip Lardon; Hans-Willem Snoeck; Zwi N Berneman; V F I Van Tendeloo; Griet Nijs; Marc Lenjou; Els Henckaerts; C J Boeckxtaens; P Vandenabeele; Luc Kestens; Dirk R Van Bockstaele; Guido Vanham
Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-alpha, and additional cytokines: antagonistic effects of IL-4 and IFN-gamma and selective involvement of TNF-alpha receptor-1.
Immunology 1997;91(4):553-9.
1996: Filip Lardon; Hans-Willem Snoeck; LR Haenen; Marc Lenjou; Griet Nijs; S F Weekx; P C Van Ranst; Zwi N Berneman; Dirk R Van Bockstaele
The combined effects of all-trans retinoic acid and TGF-beta on the initial proliferation of normal human bone marrow progenitor cells.
Leukemia 1996;10(12):1937-43.
1996: P C Van Ranst; Hans-Willem Snoeck; Filip Lardon; Marc Lenjou; Griet Nijs; S F Weekx; Inez E Rodrigus; Zwi N Berneman; Dirk R Van Bockstaele
TGF-beta and MIP-1 alpha exert their main inhibitory activity on very primitive CD34+2CD38- cells but show opposite effects on more mature CD34+CD38+ human hematopoietic progenitors.
Experimental hematology 1996;24(13):1509-15.
1996: Hans-Willem Snoeck; S Weekx; Adriaan C Moulijn; Filip Lardon; Marc Lenjou; G Nys; P C Van Ranst; Dirk R Van Bockstaele; Zwi N Berneman
Tumor necrosis factor alpha is a potent synergistic factor for the proliferation of primitive human hematopoietic progenitor cells and induces resistance to transforming growth factor beta but not to interferon gamma.
The Journal of experimental medicine 1996;183(2):705-10.
1996: Hans-Willem Snoeck; Marc Lenjou; G Nys; Filip Lardon; M E Peetermans; Dirk R Van Bockstaele; Adriaan C Moulijn; LR Haenen; Zwi N Berneman
Interleukin 4 and interferon gamma costimulate the expansion of early human myeloid colony-forming cells. Proposal of a model for the regulation of myelopoiesis by interleukin 4 and interferon gamma and its integration with the regulation of the immune response.
Leukemia 1996;10(1):117-22.
1994: Hans-Willem Snoeck; Dirk R Van Bockstaele; G Nys; Marc Lenjou; Filip Lardon; LR Haenen; Inez E Rodrigus; M E Peetermans; Zwi N Berneman
Interferon gamma selectively inhibits very primitive CD342+CD38- and not more mature CD34+CD38+ human hematopoietic progenitor cells.
The Journal of experimental medicine 1994;180(3):1177-82.
1994: Filip Lardon; Hans-Willem Snoeck; Griet Nijs; Marc Lenjou; M E Peetermans; Inez E Rodrigus; Zwi N Berneman; Dirk R Van Bockstaele
Transforming growth factor-beta regulates the cell cycle status of interleukin-3 (IL-3) plus IL-1, stem cell factor, or IL-6 stimulated CD34+ human hematopoietic progenitor cells through different cell kinetic mechanisms depending on the applied stimulus.
Experimental hematology 1994;22(9):903-9.
1994: Dirk R Van Bockstaele; Marc Lenjou; Hans-Willem Snoeck; Filip Lardon; M E Peetermans
Effect of retinoic acid (RA) on myeloid progenitors in normal bone marrow (BM)
Leukemia 1994;8(1):214-5.
1993: Hans-Willem Snoeck; Filip Lardon; Marc Lenjou; G Nys; Dirk R Van Bockstaele; M E Peetermans
Differential regulation of the expression of CD38 and human leukocyte antigen-DR on CD34+ hematopoietic progenitor cells by interleukin-4 and interferon-gamma.
Experimental hematology 1993;21(11):1480-6.
1993: Filip Lardon; Dirk R Van Bockstaele; Hans-Willem Snoeck; M E Peetermans
Quantitative cell-cycle progression analysis of the first three successive cell cycles of granulocyte colony-stimulating factor and/or granulocyte-macrophage colony-stimulating factor-stimulated human CD34+ bone marrow cells in relation to their colony formation.
Blood 1993;81(12):3211-6.
1993: Hans-Willem Snoeck; Filip Lardon; Dirk R Van Bockstaele; M E Peetermans
Effects of interleukin-4 on myelopoiesis: localization of the action of IL-4 in the CD34+HLA-DR++ subset and distinction between direct and indirect effects of IL-4.
Experimental hematology 1993;21(5):635-9.
1993: Hans-Willem Snoeck; Filip Lardon; Marc Lenjou; G Nys; Dirk R Van Bockstaele; M E Peetermans
Interferon-gamma and interleukin-4 reciprocally regulate the production of monocytes/macrophages and neutrophils through a direct effect on committed monopotential bone marrow progenitor cells.
European journal of immunology 1993;23(5):1072-7.
1993: Hans-Willem Snoeck; Filip Lardon; Dirk R Van Bockstaele; M E Peetermans
Effects of interleukin-4 (IL4) on myelopoiesis: studies on highly purified CD34+ hematopoietic progenitor cells.
Leukemia 1993;7(4):625-9.
1993: Dirk R Van Bockstaele; Marc Lenjou; Hans-Willem Snoeck; Filip Lardon; P Stryckmans; M E Peetermans
Direct effects of 13-cis and all-trans retinoic acid on normal bone marrow (BM) progenitors: comparative study on BM mononuclear cells and on isolated CD34+ BM cells.
Annals of hematology 1993;66(2):61-6.
1992: Dirk R Van Bockstaele; Filip Lardon; Hans-Willem Snoeck; M E Peetermans; M Kubbies
BrdU-Hoechst-ethidium bromide (EB) quenching technique for studying kinetics of hematopoiesis.
Blood 1992;80(1):289-91.