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William LaRochelle

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Publications

TOP 3
Xiaozhong Qian; Evan Mills; Michael Torgov; William J LaRochelle; Michael Jeffers
Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate.
Xiaozhong Qian; Gulshan Ara; Evan Mills; William J LaRochelle; Henri S Lichenstein; Michael Jeffers
Activity of the histone deacetylase inhibitor belinostat (PXD101) in preclinical models of prostate cancer.
Vincent A Pollack; Enrique Alvarez; Kam Fai Tse; Michael Y Torgov; Sam Xie; Suresh G Shenoy; John MacDougall; Sharon Arrol; Haihong Zhong; Robert W Gerwien; William F Hahne; Peter D Senter; Michael Jeffers; Henri S Lichenstein; William J LaRochelle
Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB.

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All Publications

2008: Xiaozhong Qian; Evan Mills; Michael Torgov; William J LaRochelle; Michael Jeffers
Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate.
Molecular oncology 2008;2(1):81-93.
2008: Xiaozhong Qian; Gulshan Ara; Evan Mills; William J LaRochelle; Henri S Lichenstein; Michael Jeffers
Activity of the histone deacetylase inhibitor belinostat (PXD101) in preclinical models of prostate cancer.
International journal of cancer. Journal international du cancer 2008;122(6):1400-10.
2007: Vincent A Pollack; Enrique Alvarez; Kam Fai Tse; Michael Y Torgov; Sam Xie; Suresh G Shenoy; John MacDougall; Sharon Arrol; Haihong Zhong; Robert W Gerwien; William F Hahne; Peter D Senter; Michael Jeffers; Henri S Lichenstein; William J LaRochelle
Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB.
Cancer chemotherapy and pharmacology 2007;60(3):423-35.
2007: Peter Boor; Andrzej Konieczny; Luigi Villa; Uta Kunter; Claudia van Roeyen; William J LaRochelle; Glennda Smithson; Sharon Arrol; Tammo Ostendorf; Jürgen Floege
PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(5):1323-31.
2006: Xiaozhong Qian; William J LaRochelle; Gulshan Ara; Frank Wu; Kamille Dumong Petersen; Annemette Vinding Thougaard; Maxwell Sehested; Henri S Lichenstein; Michael Jeffers
Activity of PXD101, a histone deacetylase inhibitor, in preclinical ovarian cancer studies.
Molecular cancer therapeutics 2006;5(8):2086-95.
2006: Claudia van Roeyen; Tammo Ostendorf; Bernd Denecke; Dirk Bokemeyer; Iris Behrmann; F Strutz; Henri S Lichenstein; William J LaRochelle; C E Pena; A Chaudhuri; Jürgen Floege
Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells.
Kidney international 2006;69(8):1393-402.
2006: Kam Fai Tse; Michael Jeffers; Vincent A Pollack; Denise A McCabe; Melanie L Shadish; Nikolai V Khramtsov; Craig Hackett; Suresh G Shenoy; Bing Kuang; Ferenc L Boldog; John MacDougall; Luca Rastelli; John Herrmann; Michael Gallo; Gadi Gazit-Bornstein; Peter D Senter; Damon L Meyer; Henri S Lichenstein; William J LaRochelle
CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(4):1373-82.
2005: Mohanraj Dhanabal; Michael Jeffers; William J LaRochelle; Henri S Lichenstein
Angioarrestin: a unique angiopoietin-related protein with anti-angiogenic properties.
Biochemical and biophysical research communications 2005;333(2):308-15.
2005: Mohanraj Dhanabal; Frank Wu; Enrique Alvarez; Kelly D McQueeney; Michael Jeffers; John MacDougall; Ferenc L Boldog; Craig Hackett; Suresh Shenoy; Nikolai Khramtsov; Jami Weiner; Henri S Lichenstein; William J LaRochelle
Recombinant semaphorin 6A-1 ectodomain inhibits in vivo growth factor and tumor cell line-induced angiogenesis.
Cancer biology & therapy 2005;4(6):659-68.
2005: Mohanraj Dhanabal; Michael Jeffers; William J LaRochelle
Anti-angiogenic therapy as a cancer treatment paradigm.
Current medicinal chemistry. Anti-cancer agents 2005;5(2):115-30.
2003: Tammo Ostendorf; Claudia van Roeyen; Jeffrey D Peterson; Uta Kunter; Frank Eitner; Avin J Hamad; Gerlinde Chan; Xiao-Chi Jia; Jennifer Macaluso; Gadi Gazit-Bornstein; Bruce A Keyt; Henri S Lichenstein; William J LaRochelle; Jürgen Floege
A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2003;14(9):2237-47.
2003: Enrique Alvarez; Edward G Fey; Pascal Valax; zachary yim; Jeffrey D Peterson; Medhi Mesri; Michael Jeffers; Matthew Dindinger; Nancy Twomlow; Ashwini Ghatpande; William J LaRochelle; Stephen T Sonis; Henri S Lichenstein
Preclinical characterization of CG53135 (FGF-20) in radiation and concomitant chemotherapy/radiation-induced oral mucositis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3454-61.
2002: Michael Jeffers; William J LaRochelle; Henri S Lichenstein
Fibroblast growth factors in cancer: therapeutic possibilities.
Expert opinion on therapeutic targets 2002;6(4):469-82.
2002: Mohanraj Dhanabal; William J LaRochelle; Michael Jeffers; John Herrmann; Luca Rastelli; William F McDonald; Rajeev A Chillakuru; Meijia Yang; Ferenc L Boldog; Muralidhara Padigaru; Kelly D McQueeney; Frank Wu; Stacey A Minskoff; Richard A Shimkets; Henri S Lichenstein
Angioarrestin: an antiangiogenic protein with tumor-inhibiting properties.
Cancer research 2002;62(13):3834-41.
2002: William J LaRochelle; Michael Jeffers; Jose Corvalan; Xiao-Chi Jia; Xiao Feng; Sandra Vanegas; Justin D Vickroy; Xiao-Dong Yang; Francine Chen; Gadi Gazit; Jane Mayotte; Jennifer Macaluso; Beth Rittman; Frank Wu; Mohanraj Dhanabal; John Herrmann; Henri S Lichenstein
Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer.
Cancer research 2002;62(9):2468-73.
2001: William J LaRochelle; Michael Jeffers; William F McDonald; Rajeev A Chillakuru; Neill A Giese; Nathalie A Lokker; C Sullivan; Ferenc L Boldog; Meijia Yang; C Vernet; C E Burgess; E Fernandes; L L Deegler; Beth Rittman; J Shimkets; Richard A Shimkets; Jonathan M Rothberg; Henri S Lichenstein
PDGF-D, a new protease-activated growth factor.
Nature cell biology 2001;3(5):517-21.
2001: Michael Jeffers; Richard A Shimkets; S Prayaga; Ferenc L Boldog; Meijia Yang; C Burgess; E Fernandes; Beth Rittman; J Shimkets; William J LaRochelle; Henri S Lichenstein
Identification of a novel human fibroblast growth factor and characterization of its role in oncogenesis.
Cancer research 2001;61(7):3131-8.

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