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Wouter Laroy

Research Profile

Chemicals & Drugs

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Glycosylation

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Glycomics

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Jenny E Myers; Philip N Baker; Koen Kas; Louise C Kenny; Wouter Laroy; Claire T Roberts; Nigel A B Simpson; Grégoire Thomas; Robin Tuytten; Griet Vanpoucke; Robyn A North
Integrated proteomics pipeline yields novel biomarkers for predicting preeclampsia.
Tobias Breidthardt; Beatrice Drexler; Koen Kas; Wouter Laroy; Alexandre Mebazaa; Piet Moerman; Tamina Mosimann; Mihael Potocki; Thenral Socrates; Gregoire Thomas; Griet Vanpoucke; Ronny Ziller; Christian Mueller
The novel marker LTBP2 predicts all-cause and pulmonary death in patients with acute dyspnoea.
Alexandre Mebazaa; Piet Moerman; Christian Mueller; Jane-Lise Samuel; Miguel Tavares; Gregoire Thomas; Robin Tuytten; Natalie Van Landuyt; Marc Vanderheyden; Caroline Vanhaute; Lies Vanneste; Griet Vanpoucke; Katleen Verleysen; Elisabeth Verschuere; Jan Wuyts; Jozef Bartunek; Alain Cohen-Solal; Corinne Collet; Huw Davies; Koen De Cremer; Filip D'Hondt; James L Januzzi; Wouter Laroy; Jean-Marie Launay; Damien Logeart; Brice Lortat-Jacob; Koen Kas
Unbiased plasma proteomics for novel diagnostic biomarkers in cardiovascular disease: identification of quiescin Q6 as a candidate biomarker of acutely decompensated heart failure.

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All Publications

2013: Jenny E Myers; Philip N Baker; Koen Kas; Louise C Kenny; Wouter Laroy; Claire T Roberts; Nigel A B Simpson; Grégoire Thomas; Robin Tuytten; Griet Vanpoucke; Robyn A North
Integrated proteomics pipeline yields novel biomarkers for predicting preeclampsia.
Hypertension 2013;61(6):1281-8.
2012: Tobias Breidthardt; Beatrice Drexler; Koen Kas; Wouter Laroy; Alexandre Mebazaa; Piet Moerman; Tamina Mosimann; Mihael Potocki; Thenral Socrates; Gregoire Thomas; Griet Vanpoucke; Ronny Ziller; Christian Mueller
The novel marker LTBP2 predicts all-cause and pulmonary death in patients with acute dyspnoea.
Clinical science (London, England : 1979) 2012;123(9):557-66.
2012: Alexandre Mebazaa; Piet Moerman; Christian Mueller; Jane-Lise Samuel; Miguel Tavares; Gregoire Thomas; Robin Tuytten; Natalie Van Landuyt; Marc Vanderheyden; Caroline Vanhaute; Lies Vanneste; Griet Vanpoucke; Katleen Verleysen; Elisabeth Verschuere; Jan Wuyts; Jozef Bartunek; Alain Cohen-Solal; Corinne Collet; Huw Davies; Koen De Cremer; Filip D'Hondt; James L Januzzi; Wouter Laroy; Jean-Marie Launay; Damien Logeart; Brice Lortat-Jacob; Koen Kas
Unbiased plasma proteomics for novel diagnostic biomarkers in cardiovascular disease: identification of quiescin Q6 as a candidate biomarker of acutely decompensated heart failure.
European heart journal 2012;33(18):2317-24.
2009: Dieter Vanderschaeghe; Wouter Laroy; Erwin Sablon; Philippe Halfon; Annelies Van Hecke; Joris Delanghe; Nico Callewaert
GlycoFibroTest is a highly performant liver fibrosis biomarker derived from DNA sequencer-based serum protein glycomics.
Molecular & cellular proteomics : MCP 2009;8(5):986-94.
2008: Leonardo Nimrichter; Monica M Burdick; Kazuhiro Aoki; Wouter Laroy; Mark A Fierro; Sherry A Hudson; Christopher E Von Seggern; Robert J Cotter; Bruce S Bochner; Michael Tiemeyer; Konstantinos Konstantopoulos; Ronald Schnaar
E-selectin receptors on human leukocytes.
Blood 2008;112(9):3744-52.
2008: Valerie Vanhooren; Wouter Laroy; Claude Libert; Cuiying Chen
N-glycan profiling in the study of human aging.
Biogerontology 2008;9(5):351-6.
2008: Germán H Fontanella; Kristof De Vusser; Wouter Laroy; Lucas Daurelio; Ana Lía Nocito; Silvia Revelli; Roland Contreras
Immunization with an engineered mutant trans-sialidase highly protects mice from experimental Trypanosoma cruzi infection: a vaccine candidate.
Vaccine 2008;26(19):2322-34.
2008: Xue-En Liu; Liesbeth Desmyter; Chun-fang Gao; Wouter Laroy; Sylviane Dewaele; Valerie Vanhooren; Ling Wang; Hui Zhuang; Nico Callewaert; Claude Libert; Roland Contreras; Cui-ying Chen
[N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2008;16(1):74-5.
2007: Valerie Vanhooren; Liesbeth Desmyter; Xue-En Liu; Maurizio Cardelli; Claudio Franceschi; Antonio Federico; Claude Libert; Wouter Laroy; Sylviane Dewaele; Roland Contreras; Cuiying Chen
N-glycomic changes in serum proteins during human aging.
Rejuvenation research 2007;10(4):521-531a.
2007: Xue-En Liu; Liesbeth Desmyter; Chun-Fang Gao; Wouter Laroy; Sylviane Dewaele; Valerie Vanhooren; Ling Wang; Hui Zhuang; Nico Callewaert; Claude Libert; Roland Contreras; Cuiying Chen
N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus.
Hepatology (Baltimore, Md.) 2007;46(5):1426-35.
2007: Alicja Woronowicz; Schammim Ray Amith; Vanessa W Davis; Preethi Jayanth; Kristof De Vusser; Wouter Laroy; Roland Contreras; Susan O Meakin; Myron R Szewczuk
Trypanosome trans-sialidase mediates neuroprotection against oxidative stress, serum/glucose deprivation, and hypoxia-induced neurite retraction in Trk-expressing PC12 cells.
Glycobiology 2007;17(7):725-34.
2007: Benjamin Schulz; Wouter Laroy; Nico Callewaert
Clinical laboratory testing in human medicine based on the detection of glycoconjugates.
Current molecular medicine 2007;7(4):397-416.
2007: Alicja Woronowicz; Schammim R Amith; Kristof De Vusser; Wouter Laroy; Roland Contreras; Sameh Basta; Myron R Szewczuk
Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase.
Glycobiology 2007;17(1):10-24.
2006: Wouter Laroy; Roland Contreras; Nico Callewaert
Glycome mapping on DNA sequencing equipment.
Nature protocols 2006;1(1):397-405.
2006: Thomas Weide; Lutz Herrmann; Ulrike Bockau; Nadine Niebur; Ingo Aldag; Wouter Laroy; Roland Contreras; Arno Tiedtke; Marcus W W Hartmann
Secretion of functional human enzymes by Tetrahymena thermophila.
BMC biotechnology 2006;6():19.
2004: Alicja Woronowicz; Kristof De Vusser; Wouter Laroy; Roland Contreras; Susan O Meakin; Gregory M Ross; Myron R Szewczuk
Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation.
Glycobiology 2004;14(11):987-98.
2004: Nico Callewaert; Hans Van Vlierberghe; Annelies Van Hecke; Wouter Laroy; Joris Delanghe; Roland Contreras
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics.
Nature medicine 2004;10(4):429-34.
2002: Y Gong; Y Tagawa; M P T Lunn; Wouter Laroy; Marija Heffer-Lauc; C Y Li; John W Griffin; Ronald Schnaar; Kazim A Sheikh
Localization of major gangliosides in the PNS: implications for immune neuropathies.
Brain : a journal of neurology 2002;125(Pt 11):2491-506.
2002: Yumi Tagawa; Wouter Laroy; Leonardo Nimrichter; Susan E Fromholt; Ann B Moser; Hugo W Moser; Ronald Schnaar
Anti-ganglioside antibodies bind with enhanced affinity to gangliosides containing very long chain fatty acids.
Neurochemical research 2002;27(7-8):847-55.
2002: John L Moriarity; K Joseph Hurt; Adam C Resnick; Phillip B Storm; Wouter Laroy; Ronald Schnaar; Solomon H Snyder
UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization.
The Journal of biological chemistry 2002;277(19):16968-75.
2002: Ronald Schnaar; Susan E Fromholt; Yanping Gong; Alka A Vyas; Wouter Laroy; Dawn M Wayman; Marija Heffer-Lauc; Hiromi Ito; Hideharu Ishida; Makoto Kiso; John W Griffin; Kazim A Shiekh
Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides.
Analytical biochemistry 2002;302(2):276-84.
2001: Nico Callewaert; Wouter Laroy; H Cadirgi; Steven Geysens; Xavier Saelens; Willy Min Jou; Roland Contreras
Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris.
FEBS letters 2001;503(2-3):173-8.
2001: Wouter Laroy; Paul Ameloot; Roland Contreras
Characterization of sialyltransferase mutants using surface plasmon resonance.
Glycobiology 2001;11(3):175-82.
2000: Wouter Laroy; Roland Contreras
Cloning of Trypanosoma cruzi trans-sialidase and expression in Pichia pastoris.
Protein expression and purification 2000;20(3):389-93.
1997: Marleen Maras; Xavier Saelens; Wouter Laroy; Kathleen Piens; Marc Claeyssens; Walter Fiers; Roland Contreras
In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides--evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei.
European journal of biochemistry / FEBS 1997;249(3):701-7.
1997: Wouter Laroy; Marleen Maras; Walter Fiers; Roland Contreras
A radioactive assay for sialyltransferase activity using 96-well multiscreen filtration plates.
Analytical biochemistry 1997;249(1):108-11.