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Lesley Larsen

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Zong-Quan Ou; Thomas Rades; David M Schmierer; Lesley Larsen; Arlene McDowell
Application of an online post-column derivatization HPLC-DPPH assay to detect compounds responsible for antioxidant activity in Sonchus oleraceus L. leaf extracts.
Euphemia Leung; Gordon W Rewcastle; Rhonda J Rosengren; Wayne R Joseph; Lesley Larsen; Bruce C Baguley
Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells.
Babasaheb Yadav; Sebastien Taurin; Lesley Larsen; Rhonda J Rosengren
RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER‑negative breast cancer models.

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2013: Zong-Quan Ou; Thomas Rades; David M Schmierer; Lesley Larsen; Arlene McDowell
Application of an online post-column derivatization HPLC-DPPH assay to detect compounds responsible for antioxidant activity in Sonchus oleraceus L. leaf extracts.
The Journal of pharmacy and pharmacology 2013;65(2):271-9.
2012: Euphemia Leung; Gordon W Rewcastle; Rhonda J Rosengren; Wayne R Joseph; Lesley Larsen; Bruce C Baguley
Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells.
Investigational new drugs 2012;30(6):2103-12.
2012: Babasaheb Yadav; Sebastien Taurin; Lesley Larsen; Rhonda J Rosengren
RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER‑negative breast cancer models.
International journal of oncology 2012;41(5):1723-32.
2012: Babasaheb Yadav; Sebastien Taurin; Lesley Larsen; Rhonda J Rosengren
RL71, a second-generation curcumin analog, induces apoptosis and downregulates Akt in ER-negative breast cancer cells.
International journal of oncology 2012;41(3):1119-27.
2011: Tiffany J Somers-Edgar; Sebastien Taurin; Lesley Larsen; Anupama Chandramouli; Mark A Nelson; Rhonda J Rosengren
Mechanisms for the activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines.
Investigational new drugs 2011;29(1):87-97.
2010: Babasaheb Yadav; Sebastien Taurin; Rhonda J Rosengren; Marc Schumacher; Marc Diederich; Tiffany J Somers-Edgar; Lesley Larsen
Synthesis and cytotoxic potential of heterocyclic cyclohexanone analogues of curcumin.
Bioorganic & medicinal chemistry 2010;18(18):6701-7.
2009: Franck E Dayan; Nidhi Singh; Christopher R McCurdy; Colette A Godfrey; Lesley Larsen; Rex T Weavers; John W Van Klink; Nigel B Perry
Beta-triketone inhibitors of plant p-hydroxyphenylpyruvate dioxygenase: modeling and comparative molecular field analysis of their interactions.
Journal of agricultural and food chemistry 2009;57(12):5194-200.
2007: Catherine E Sansom; Lesley Larsen; Nigel B Perry; Michael V Berridge; Elizabeth W Chia; Jacquie L Harper; Victoria L Webb
An antiproliferative bis-prenylated quinone from the New Zealand brown alga Perithalia capillaris.
Journal of natural products 2007;70(12):2042-4.
2007: David A J Teulon; Melanie M Davidson; Duncan I Hedderley; Dale E James; Callum D Fletcher; Lesley Larsen; Vanessa C Green; Nigel B Perry
4-pyridyl carbonyl and related compounds as thrips lures: effectiveness for onion thrips and new zealand flower thrips in field experiments.
Journal of agricultural and food chemistry 2007;55(15):6198-205.
2007: A Norrie Pearce; Elizabeth W Chia; Michael V Berridge; George R Clark; Jacquie L Harper; Lesley Larsen; Elizabeth Maas; Michael J Page; Nigel B Perry; Victoria L Webb; Brent Copp
Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis.
Journal of natural products 2007;70(6):936-40.
2007: Emma C Stuart; Lesley Larsen; Rhonda J Rosengren
Potential mechanisms for the synergistic cytotoxicity elicited by 4-hydroxytamoxifen and epigallocatechin gallate in MDA-MB-231 cells.
International journal of oncology 2007;30(6):1407-12.
2006: Nerida J Brennan; Lesley Larsen; Stephen D Lorimer; Nigel B Perry; Eleanor L Chapin; Todd L Werk; Matthew J Henry; Donald R Hahn
Fungicidal sesquiterpene dialdehyde cinnamates from Pseudowintera axillaris.
Journal of agricultural and food chemistry 2006;54(2):468-73.
2005: John W van Klink; Lesley Larsen; Nigel B Perry; Rex T Weavers; Gregory Cook; Phil J Bremer; Andrew D MacKenzie; Teruo Kirikae
Triketones active against antibiotic-resistant bacteria: synthesis, structure-activity relationships, and mode of action.
Bioorganic & medicinal chemistry 2005;13(24):6651-62.
2005: Lesley Larsen; Michael H Benn; Masood Parvez; Nigel B Perry
A cytotoxic triketone-phloroglucinol-bullatenone hybrid from Lophomyrtus bullata.
Organic & biomolecular chemistry 2005;3(17):3236-41.
2005: Catherine E McNamara; Lesley Larsen; Nigel B Perry; Jacquie L Harper; Michael V Berridge; Elizabeth W Chia; Michelle Kelly; Victoria L Webb
Anti-inflammatory sesquiterpene-quinones from the New Zealand sponge Dysidea cf. cristagalli.
Journal of natural products 2005;68(9):1431-3.
2000: E J Burgess; Lesley Larsen; Nigel B Perry
A cytotoxic sesquiterpene caffeate from the liverwort Bazzanianovae-zelandiae.
Journal of natural products 2000;63(4):537-9.