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Richard Lathrop

Research Profile

Concepts & Ideas

Chemicals & Drugs

Occupations

Physiology

Activities & Behaviors

Artificial Intelligence

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

Phenomena

Protein Binding

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Publications

TOP 3
Christopher D Wassman; Özlem Demir; Roberta Baronio; Chiung-Kuang Chen; Benjamin P Chung; Linda V Hall; G Wesley Hatfield; Peter Kaiser; Richard H Lathrop; Da-Wei Lin; Hartmut Luecke; A Richard Chamberlin; Faezeh Salehi; Brad D Wallentine; Rommie E Amaro
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53.
Johnny C Akers; HoangMinh HoDac; Richard H Lathrop; Ming Tan
Identification and functional analysis of CT069 as a novel transcriptional regulator in Chlamydia.
Özlem Demir; Roberta Baronio; Richard Chamberlin; Linda Hall; G Wesley Hatfield; Peter Kaiser; Richard H Lathrop; Faezeh Salehi; Christopher D Wassman; Rommie E Amaro
Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants.

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All Publications

2013: Christopher D Wassman; Özlem Demir; Roberta Baronio; Chiung-Kuang Chen; Benjamin P Chung; Linda V Hall; G Wesley Hatfield; Peter Kaiser; Richard H Lathrop; Da-Wei Lin; Hartmut Luecke; A Richard Chamberlin; Faezeh Salehi; Brad D Wallentine; Rommie E Amaro
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53.
Nature communications 2013;4():1407.
2011: Johnny C Akers; HoangMinh HoDac; Richard H Lathrop; Ming Tan
Identification and functional analysis of CT069 as a novel transcriptional regulator in Chlamydia.
Journal of bacteriology 2011;193(22):6123-31.
2011: Özlem Demir; Roberta Baronio; Richard Chamberlin; Linda Hall; G Wesley Hatfield; Peter Kaiser; Richard H Lathrop; Faezeh Salehi; Christopher D Wassman; Rommie E Amaro
Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants.
PLoS computational biology 2011;7(10):e1002238.
2011: Gene-Errol Ringpis; Richard H Lathrop; Ruslan Aphasizhev
iCODA: RNAi-based inducible knock-in system in Trypanosoma brucei.
Methods in molecular biology (Clifton, N.J.) 2011;718():23-37.
2010: Roberta Baronio; Samuel A Danziger; Linda V Hall; Kirsty Salmon; G Wesley Hatfield; Richard H Lathrop; Peter Kaiser
All-codon scanning identifies p53 cancer rescue mutations.
Nucleic acids research 2010;38(20):7079-88.
2010: Gene-Errol Ringpis; Inna Aphasizheva; Xiaorong Wang; Lan Huang; Richard H Lathrop; G Wesley Hatfield; Ruslan Aphasizhev
Mechanism of U insertion RNA editing in trypanosome mitochondria: the bimodal TUTase activity of the core complex.
Journal of molecular biology 2010;399(5):680-95.
2009: Samuel A Danziger; Roberta Baronio; Lydia Ho; Linda Hall; Kirsty Salmon; G Wesley Hatfield; Peter Kaiser; Richard H Lathrop
Predicting positive p53 cancer rescue regions using Most Informative Positive (MIP) active learning.
PLoS computational biology 2009;5(9):e1000498.
2008: Jue Zeng; Jizhou Yan; Ting Wang; Deborah Mosbrook-Davis; Kyle T Dolan; Ryan Christensen; Gary stormo; David Haussler; Richard H Lathrop; Rainer K Brachmann; Shawn M Burgess
Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins.
Nucleic acids research 2008;36(1):e8.
2007: Samuel A Danziger; Jue Zeng; Ying Wang; Rainer K Brachmann; Richard H Lathrop
Choosing where to look next in a mutation sequence space: Active Learning of informative p53 cancer rescue mutants.
Bioinformatics (Oxford, England) 2007;23(13):i104-14.
2007: Mert Döşkaya; Mina Kalantari-Dehaghi; Craig M Walsh; Elzbieta Hiszczyńska-Sawicka; D Huw Davies; Philip L Felgner; Liza S Z Larsen; Richard H Lathrop; G Wesley Hatfield; Jessica R Schulz; Yüksel Gürüz; Frances Jurnak
GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine.
Vaccine 2007;25(10):1824-37.
2007: Kimberly A Aeling; Nicholas R Steffen; Matthew Johnson; G Wesley Hatfield; Richard H Lathrop; Donald F Senear
DNA deformation energy as an indirect recognition mechanism in protein-DNA interactions.
IEEE/ACM transactions on computational biology and bioinformatics / IEEE, ACM 2007;4(1):117-25.
2006: Kimberly A Aeling; Michael L Opel; Nicholas R Steffen; Vira Tretyachenko-Ladokhina; G Wesley Hatfield; Richard H Lathrop; Donald F Senear
Indirect recognition in sequence-specific DNA binding by Escherichia coli integration host factor: the role of DNA deformation energy.
The Journal of biological chemistry 2006;281(51):39236-48.
2006: Christian Tagwerker; Hongwei Zhang; Xiaorong Wang; Liza S Z Larsen; Richard H Lathrop; G Wesley Hatfield; Bernhard Auer; Lan Huang; Peter Kaiser
HB tag modules for PCR-based gene tagging and tandem affinity purification in Saccharomyces cerevisiae.
Yeast (Chichester, England) 2006;23(8):623-32.
2006: Samuel A Danziger; S Joshua Swamidass; Jue Zeng; Lawrence R Dearth; Qiang Lu; Jonathan H Chen; Jianlin Cheng; Vinh P Hoang; Hiroto Saigo; Ray Luo; Pierre Baldi; Rainer K Brachmann; Richard H Lathrop
Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants.
IEEE/ACM transactions on computational biology and bioinformatics / IEEE, ACM 2006;3(2):114-25.
2004: Christopher D Wassman; Phillip Y Tam; Richard H Lathrop; Gregory A Weiss
Predicting oligonucleotide-directed mutagenesis failures in protein engineering.
Nucleic acids research 2004;32(21):6407-13.
2002: Melissa Cline; Kevin Karplus; Richard H Lathrop; Temple F Smith; Robert G Rogers; David Haussler
Information-theoretic dissection of pairwise contact potentials.
Proteins 2002;49(1):7-14.
2002: Nicholas R Steffen; Scott D Murphy; Richard H Lathrop; Michael L Opel; Lorenzo Tolleri; G Wesley Hatfield
The role of DNA deformation energy at individual base steps for the identification of DNA-protein binding sites.
Genome informatics. International Conference on Genome Informatics 2002;13():153-62.
2002: Nicholas R Steffen; S D Murphy; Lorenzo Tolleri; G Wesley Hatfield; Richard H Lathrop
DNA sequence and structure: direct and indirect recognition in protein-DNA binding.
Bioinformatics (Oxford, England) 2002;18 Suppl 1():S22-30.
1999: Richard H Lathrop
An anytime local-to-global optimization algorithm for protein threading in theta (m2ñ2) space.
Journal of computational biology : a journal of computational molecular cell biology 1999;6(3-4):405-18.
1998: Richard H Lathrop; R G Rogers; T F Smith; J V White
A Bayes-optimal sequence-structure theory that unifies protein sequence-structure recognition and alignment.
Bulletin of mathematical biology 1998;60(6):1039-71.
1998: Richard H Lathrop; Malcolm Casale; Douglas J Tobias; J Lawrence Marsh; Leslie Michels Thompson
Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.
Proceedings / ... International Conference on Intelligent Systems for Molecular Biology ; ISMB. International Conference on Intelligent Systems for Molecular Biology 1998;6():105-14.
1997: Temple F Smith; L Lo Conte; Jadwiga R Bienkowska; C Gaitatzes; RG Rogers; Richard H Lathrop
Current limitations to protein threading approaches.
Journal of computational biology : a journal of computational molecular cell biology 1997;4(3):217-25.