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Francesco Latrofa

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Chemicals & Drugs

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Graves' Disease

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TOP 3
Yumiko Mizutori; Chun-Rong Chen; Francesco Latrofa; Sandra M McLachlan; Basil Rapoport
Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves' disease.
Francesco Latrofa; Gregorio Chazenbalk; Sandra M McLachlan; Basil Rapoport
Evidence that the thyrotropin receptor protease is membrane-associated and is not within lipid rafts.
Francesco Latrofa; Martin Phillips; Basil Rapoport; Sandra M McLachlan
Human monoclonal thyroglobulin autoantibodies: epitopes and immunoglobulin genes.

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2009: Yumiko Mizutori; Chun-Rong Chen; Francesco Latrofa; Sandra M McLachlan; Basil Rapoport
Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves' disease.
The Journal of clinical endocrinology and metabolism 2009;94(3):927-35.
2004: Francesco Latrofa; Gregorio Chazenbalk; Sandra M McLachlan; Basil Rapoport
Evidence that the thyrotropin receptor protease is membrane-associated and is not within lipid rafts.
Thyroid : official journal of the American Thyroid Association 2004;14(10):801-5.
2004: Francesco Latrofa; Martin Phillips; Basil Rapoport; Sandra M McLachlan
Human monoclonal thyroglobulin autoantibodies: epitopes and immunoglobulin genes.
The Journal of clinical endocrinology and metabolism 2004;89(10):5116-23.
2004: Francesco Latrofa; Gregorio Chazenbalk; Pavel N Pichurin; Chun-Rong Chen; Sandra M McLachlan; Basil Rapoport
Affinity-enrichment of thyrotropin receptor autoantibodies from Graves' patients and normal individuals provides insight into their properties and possible origin from natural antibodies.
The Journal of clinical endocrinology and metabolism 2004;89(9):4734-45.
2004: Gregorio Chazenbalk; Francesco Latrofa; Sandra M McLachlan; Basil Rapoport
Thyroid stimulation does not require antibodies with identical epitopes but does involve recognition of a critical conformation at the N terminus of the thyrotropin receptor A-subunit.
The Journal of clinical endocrinology and metabolism 2004;89(4):1788-93.
2003: Chun-Rong Chen; Pavel N Pichurin; Yuji Nagayama; Francesco Latrofa; Basil Rapoport; Sandra M McLachlan
The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim.
The Journal of clinical investigation 2003;111(12):1897-904.
2003: Francesco Latrofa; Pavel N Pichurin; Jin Guo; Basil Rapoport; Sandra M McLachlan
Thyroglobulin-thyroperoxidase autoantibodies are polyreactive, not bispecific: analysis using human monoclonal autoantibodies.
The Journal of clinical endocrinology and metabolism 2003;88(1):371-8.
2002: Gregorio Chazenbalk; Pavel N Pichurin; Chun-Rong Chen; Francesco Latrofa; Alan P Johnstone; Sandra M McLachlan; Basil Rapoport
Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor.
The Journal of clinical investigation 2002;110(2):209-17.