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Roberta Lattanzi

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Chemicals & Drugs

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Pain

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Rossella Miele; Roberta Lattanzi; Maria Carmela Bonaccorsi di Patti; Alessandro Paiardini; Lucia Negri; Donatella Barra
Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding.
Elisa Giannini; Roberta Lattanzi; Annalisa Nicotra; Antonio F Campese; Paola Grazioli; Isabella Screpanti; Gianfranco Balboni; Severo Salvadori; Paola Sacerdote; Lucia Negri
The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain.
Steven Ballet; Debby Feytens; Rien De Wachter; Magali De Vlaeminck; Ewa D Marczak; Severo Salvadori; Chris de Graaf; Didier Rognan; Lucia Negri; Roberta Lattanzi; Lawrence H Lazarus; Dirk Tourwé; Gianfranco Balboni
Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold.

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All Publications

2010: Rossella Miele; Roberta Lattanzi; Maria Carmela Bonaccorsi di Patti; Alessandro Paiardini; Lucia Negri; Donatella Barra
Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding.
Protein expression and purification 2010;73(1):10-4.
2009: Elisa Giannini; Roberta Lattanzi; Annalisa Nicotra; Antonio F Campese; Paola Grazioli; Isabella Screpanti; Gianfranco Balboni; Severo Salvadori; Paola Sacerdote; Lucia Negri
The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14646-51.
2009: Steven Ballet; Debby Feytens; Rien De Wachter; Magali De Vlaeminck; Ewa D Marczak; Severo Salvadori; Chris de Graaf; Didier Rognan; Lucia Negri; Roberta Lattanzi; Lawrence H Lazarus; Dirk Tourwé; Gianfranco Balboni
Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold.
Bioorganic & medicinal chemistry letters 2009;19(2):433-7.
2007: Vito de Novellis; Lucia Negri; Roberta Lattanzi; Francesca Rossi; Enza Palazzo; Ida Marabese; Elisa Giannini; Daniela Vita; Pietro Melchiorri; Sabatino Maione
The prokineticin receptor agonist Bv8 increases GABA release in the periaqueductal grey and modifies RVM cell activities and thermoceptive reflexes in the rat.
The European journal of neuroscience 2007;26(11):3068-78.
2007: Severo Salvadori; Claudio Trapella; Stella Fiorini; Lucia Negri; Roberta Lattanzi; Sharon D Bryant; Yunden Jinsmaa; Lawrence H Lazarus; Gianfranco Balboni
A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-Tic.
Bioorganic & medicinal chemistry 2007;15(22):6876-81.
2007: Lucia Negri; Roberta Lattanzi; Elisa Giannini; Pietro Melchiorri
Bv8/Prokineticin proteins and their receptors.
Life sciences 2007;81(14):1103-16.
2007: Laura Biondi; Fernando Filira; Elisa Giannini; Marina Gobbo; Roberta Lattanzi; Lucia Negri; Raniero Rocchi
Novel glycosylated [Lys(7)]-dermorphin analogues: synthesis, biological activity and conformational investigations.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(3):179-89.
2006: Francesco E Pontieri; Roberta Lattanzi; Dario Benincasa; Michele Cavallari; Lucia Negri; Francesco Orzi
Effects of the intravenous administration of [Lys7]dermorphin on local cerebral glucose utilization in the rat.
European journal of pharmacology 2006;544(1-3):17-20.
2006: Lucia Negri; Roberta Lattanzi; Elisa Giannini; Pietro Melchiorri
Modulators of pain: Bv8 and prokineticins.
Current neuropharmacology 2006;4(3):207-15.
2006: Steven Ballet; Severo Salvadori; Claudio Trapella; Sharon D Bryant; Yunden Jinsmaa; Lawrence H Lazarus; Lucia Negri; Elisa Giannini; Roberta Lattanzi; Dirk Tourwé; Gianfranco Balboni
New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands.
Journal of medicinal chemistry 2006;49(13):3990-3.
2006: Lucia Negri; Roberta Lattanzi; Elisa Giannini; Mariantonella Colucci; Federica Margheriti; Pietro Melchiorri; Vittorio Vellani; Hui Tian; Milena De Felice; Frank Porreca
Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(25):6716-27.
2006: M. Eugenio Vázquez; Juan B Blanco; Severo Salvadori; Claudio Trapella; Roberto Argazzi; Sharon D Bryant; Yunden Jinsmaa; Lawrence H Lazarus; Lucia Negri; Elisa Giannini; Roberta Lattanzi; Mariantonella Colucci; Gianfranco Balboni
6-N,N-dimethylamino-2,3-naphthalimide: a new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides.
Journal of medicinal chemistry 2006;49(12):3653-8.
2006: Vittorio Vellani; Mariantonella Colucci; Roberta Lattanzi; Elisa Giannini; Lucia Negri; Pietro Melchiorri; Peter A McNaughton
Sensitization of transient receptor potential vanilloid 1 by the prokineticin receptor agonist Bv8.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(19):5109-16.
2005: Lucia Negri; Roberta Lattanzi; Elisa Giannini; Mariantonella Colucci; Giuseppina Mignogna; Donatella Barra; Fabio Grohovaz; Franca Codazzi; Alessandra Kaiser; Günther Kreil; Pietro Melchiorri
Biological activities of Bv8 analogues.
British journal of pharmacology 2005;146(5):625-32.
2005: Roberta Lattanzi; Mariana Spetea; Falko Schüllner; Silvia B Rief; Roland Krassnig; Lucia Negri; Helmut Schmidhammer
Synthesis and biological evaluation of 14-alkoxymorphinans. 22.(1) Influence of the 14-alkoxy group and the substitution in position 5 in 14-alkoxymorphinan-6-ones on in vitro and in vivo activities.
Journal of medicinal chemistry 2005;48(9):3372-8.
2004: Gianfranco Balboni; Severo Salvadori; Alessandro Dal Piaz; Fabrizio Bortolotti; Roberto Argazzi; Lucia Negri; Roberta Lattanzi; Sharon D Bryant; Yunden Jinsmaa; Lawrence H Lazarus
Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.
Journal of medicinal chemistry 2004;47(26):6541-6.
2004: Lucia Negri; Roberta Lattanzi; Elisa Giannini; Milena De Felice; Antonella Colucci; Pietro Melchiorri
Bv8, the amphibian homologue of the mammalian prokineticins, modulates ingestive behaviour in rats.
British journal of pharmacology 2004;142(1):181-91.
2002: Lucia Negri; Roberta Lattanzi; Elisa Giannini; Alessio Metere; Mariantonella Colucci; Donatella Barra; Günther Kreil; Pietro Melchiorri
Nociceptive sensitization by the secretory protein Bv8.
British journal of pharmacology 2002;137(8):1147-54.
2002: Roberta Lattanzi; Lucia Negri; Helmut Schmidhammer; Elisa Giannini
Antinociceptive activity of a novel buprenorphine analogue.
Life sciences 2002;70(18):2177-85.
2001: Roberta Lattanzi; Lucia Negri; Elisa Giannini; Helmut Schmidhammer; J Schutz; Giovanna Improta
HS-599: a novel long acting opioid analgesic does not induce place-preference in rats.
British journal of pharmacology 2001;134(2):441-7.
2001: Susan Slowe; Siân Clarke; I Lena; Robin J Goody; Roberta Lattanzi; Lucia Negri; Frédéric Simonin; H W D Matthes; Dominique Filliol; Jerome Becker; Ian Kitchen
Autoradiographic mapping of the opioid receptor-like 1 (ORL1) receptor in the brains of mu-, delta- or kappa-opioid receptor knockout mice.
Neuroscience 2001;106(3):469-80.
2000: Lucia Negri; Pietro Melchiorri; Roberta Lattanzi
Pharmacology of amphibian opiate peptides.
Peptides 2000;21(11):1639-47.
1999: Lucia Negri; Maria Broccardo; Roberta Lattanzi; Pietro Melchiorri
Effects of antisense oligonucleotides on brain delta-opioid receptor density and on SNC80-induced locomotor stimulation and colonic transit inhibition in rats.
British journal of pharmacology 1999;128(7):1554-60.
1999: Lucia Negri; Roberta Lattanzi; Anna Borsodi; G Toth; Severo Salvadori
Differential knockdown of delta-opioid receptor subtypes in the rat brain by antisense oligodeoxynucleotides targeting mRNA.
Antisense & nucleic acid drug development 1999;9(2):203-11.
1999: Lucia Negri; Roberta Lattanzi; Fabio Tabacco; L Orrù; Cinzia Severini; Barbara Scolaro; Raniero Rocchi
Dermorphin and deltorphin glycosylated analogues: synthesis and antinociceptive activity after systemic administration.
Journal of medicinal chemistry 1999;42(3):400-4.
1998: Lucia Negri; Roberta Lattanzi; Fabio Tabacco; Barbara Scolaro; Raniero Rocchi
Glycodermorphins: opioid peptides with potent and prolonged analgesic activity and enhanced blood-brain barrier penetration.
British journal of pharmacology 1998;124(7):1516-22.
1998: Lucia Negri; Roberta Lattanzi; Fabio Tabacco; Pietro Melchiorri
Respiratory and cardiovascular effects of the mu-opioid receptor agonist [Lys7]dermorphin in awake rats.
British journal of pharmacology 1998;124(2):345-55.
1997: Lucia Negri; Cinzia Severini; Roberta Lattanzi; Rosa Luisa Potenza; Pietro Melchiorri
Postnatal development of delta-opioid receptor subtypes in mice.
British journal of pharmacology 1997;120(6):989-94.
1995: Lucia Negri; Giovanna Improta; Roberta Lattanzi; R L Potenza; F Luchetti; Pietro Melchiorri
Interaction between the mu-agonist dermorphin and the delta-agonist [D-Ala2, Glu4]deltorphin in supraspinal antinociception and delta-opioid receptor binding.
British journal of pharmacology 1995;116(7):2931-8.
1995: A Trovati; Paola Cinti; M L Tamburro; Roberta Lattanzi; V Baiano; AM Orlandini; Elvira Renna-Molajoni; Raffaello Cortesini
Immunological analysis of kidney allograft infiltrates during rejection: presence of cells coexpressing CD4 and CD8 antigens.
Transplantation proceedings 1995;27(1):930-1.
1995: Lucia Negri; Roberta Lattanzi; Pietro Melchiorri
Production of antinociception by peripheral administration of [Lys7]dermorphin, a naturally occurring peptide with high affinity for mu-opioid receptors.
British journal of pharmacology 1995;114(1):57-66.