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Serrine Lau

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Terrence J Monks; Serrine S Lau
Reactive intermediates: molecular and MS-based approaches to assess the functional significance of chemical-protein adducts.
Fengjiao Zhang; Serrine S Lau; Terrence J Monks
A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis.
Ricardo J Flores; Ching C Lau; Serrine S Lau; Yiting Li; Pulivarthi H Rao; Jianhe Shen; Marina Vannucci; Alexander Yu; Tsz-Kwong Man
A systems biology approach reveals common metastatic pathways in osteosarcoma.

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2013: Terrence J Monks; Serrine S Lau
Reactive intermediates: molecular and MS-based approaches to assess the functional significance of chemical-protein adducts.
Toxicologic pathology 2013;41(2):315-21.
2012: Fengjiao Zhang; Serrine S Lau; Terrence J Monks
A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis.
Toxicological sciences : an official journal of the Society of Toxicology 2012;128(1):103-14.
2012: Ricardo J Flores; Ching C Lau; Serrine S Lau; Yiting Li; Pulivarthi H Rao; Jianhe Shen; Marina Vannucci; Alexander Yu; Tsz-Kwong Man
A systems biology approach reveals common metastatic pathways in osteosarcoma.
BMC systems biology 2012;6():50.
2011: Shawn M Wnek; Jeannie M Camarillo; Christopher L Kuhlman; Serrine S Lau; Ke J Liu; Matthew K Medeiros; A Gandolfi
Interdependent genotoxic mechanisms of monomethylarsonous acid: role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells.
Toxicology and applied pharmacology 2011;257(1):1-13.
2011: Jennifer D Cohen; Justin D Dietrich; Jaime M C Gard; Terrence J Monks; Raymond B Nagle; Serrine S Lau
ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.
Toxicological sciences : an official journal of the Society of Toxicology 2011;124(1):75-87.
2011: Jennifer D Cohen; Alfred C Gallegos; Nicholas J Mastrandrea; Terrence J Monks; Kimberly Y Tham; Serrine S Lau
cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.
Toxicological sciences : an official journal of the Society of Toxicology 2011;122(2):361-71.
2011: Michael J Kimzey; Xristo Zarate; David W Galbraith; Serrine S Lau
Optimizing microarray-based in situ transcription-translation of proteins for matrix-assisted laser desorption ionization mass spectrometry.
Analytical biochemistry 2011;414(2):282-6.
2011: Susan P Felter; Jay I Goodman; Wafa A Harrouk; David J Kirkland; Serrine S Lau; G Craig Llewellyn; R Julian Preston; A Robert Schnatter; Rita Schoeny; Angelika Tritscher; Frans van Velsen; Joel P Bercu; P Michael Bolger; Alan R Boobis; Peter M J Bos; Philip Carthew; Rory B Conolly; Nancy G Doerrer; Gary M Williams
A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens.
Critical reviews in toxicology 2011;41(6):507-44.
2011: Ashley A Fisher; Matthew T Labenski; Shawn B Bratton; John D Chapman; Srinivas Malladi; Terrence J Monks; Serrine S Lau
The frequency of 1,4-benzoquinone-lysine adducts in cytochrome c correlate with defects in apoptosome activation.
Toxicological sciences : an official journal of the Society of Toxicology 2011;122(1):64-72.
2011: Michael J Kimzey; Hussein N Yassine; Brent M Riepel; George Tsaprailis; Terrence J Monks; Serrine S Lau
New site(s) of methylglyoxal-modified human serum albumin, identified by multiple reaction monitoring, alter warfarin binding and prostaglandin metabolism.
Chemico-biological interactions 2011;192(1-2):122-8.
2011: Fengjiao Zhang; Serrine S Lau; Terrence J Monks
The cytoprotective effect of N-acetyl-L-cysteine against ROS-induced cytotoxicity is independent of its ability to enhance glutathione synthesis.
Toxicological sciences : an official journal of the Society of Toxicology 2011;120(1):87-97.
2011: Matthew T Labenski; Ashley A Fisher; Terrence J Monks; Serrine S Lau
Identification of chemical-adducted proteins in urine by multi-dimensional protein identification technology (LC/LC-MS/MS).
Methods in molecular biology (Clifton, N.J.) 2011;691():339-47.
2011: Matthew T Labenski; Ashley A Fisher; Terrence J Monks; Serrine S Lau
One-dimensional western blotting coupled to LC-MS/MS analysis to identify chemical-adducted proteins in rat urine.
Methods in molecular biology (Clifton, N.J.) 2011;691():327-38.
2011: Ashley A Fisher; Matthew T Labenski; Terrence J Monks; Serrine S Lau
Utilization of LC-MS/MS analyses to identify site-specific chemical protein adducts in vitro.
Methods in molecular biology (Clifton, N.J.) 2011;691():317-26.
2011: Ashley A Fisher; Matthew T Labenski; Terrence J Monks; Serrine S Lau
Utilization of MALDI-TOF to determine chemical-protein adduct formation in vitro.
Methods in molecular biology (Clifton, N.J.) 2011;691():303-16.
2010: Terrence J Monks; Michael Butterworth; Serrine S Lau
The fate of benzene-oxide.
Chemico-biological interactions 2010;184(1-2):201-6.
2010: Serrine S Lau; Christopher L Kuhlman; Shawn B Bratton; Terrence J Monks
Role of hydroquinone-thiol conjugates in benzene-mediated toxicity.
Chemico-biological interactions 2010;184(1-2):212-7.
2009: Ximena Perfetti; Brian O'Mathúna; Nieves Pizarro; Elisabet Cuyàs; Olha Khymenets; Bruno Almeida; Manuela Pellegrini; Simona Pichini; Serrine S Lau; Terrence J Monks; Magí Farré; Jose Antonio Pascual; Jesús Joglar; Rafael de la Torre
Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(7):1448-55.
2009: Matthew T Labenski; Ashley A Fisher; Herng-Hsiang Lo; Terrence J Monks; Serrine S Lau
Protein electrophile-binding motifs: lysine-rich proteins are preferential targets of quinones.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(6):1211-8.
2008: Nieves Pizarro; Rafael de la Torre; Jesús Joglar; Noriko Okumura; Ximena Perfetti; Serrine S Lau; Terrence J Monks
Serotonergic neurotoxic thioether metabolites of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): synthesis, isolation, and characterization of diastereoisomers.
Chemical research in toxicology 2008;21(12):2272-9.
2008: Gladys V Erives; Serrine S Lau; Terrence J Monks
Accumulation of neurotoxic thioether metabolites of 3,4-(+/-)-methylenedioxymethamphetamine in rat brain.
The Journal of pharmacology and experimental therapeutics 2008;324(1):284-91.
2007: Ashley A Fisher; Matthew T Labenski; Srinivas Malladi; Vijay Gokhale; Martina E Bowen; Rania S Milleron; Shawn B Bratton; Terrence J Monks; Serrine S Lau
Quinone electrophiles selectively adduct "electrophile binding motifs" within cytochrome c.
Biochemistry 2007;46(39):11090-100.
2007: Ryan Wozniak; Walter T Klimecki; Serrine S Lau; Y Feinstein; Bernard W Futscher
5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation.
Oncogene 2007;26(1):77-90.
2006: Kylee E Eblin; Martina E Bowen; D W Cromey; Tiffany G Bredfeldt; Eugene A. Mash Jr.; Serrine S Lau; A Gandolfi
Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture.
Toxicology and applied pharmacology 2006;217(1):7-14.
2006: Terrence J Monks; Ruiyu Xie; Kulbhushan Tikoo; Serrine S Lau
Ros-induced histone modifications and their role in cell survival and cell death.
Drug metabolism reviews 2006;38(4):755-67.
2005: Mi Young Yang; Serrine S Lau; Terrence J Monks
2,3,5-tris(Glutathion-S-yl)hydroquinone (TGHQ)-mediated apoptosis of human promyelocytic leukemia cells is preceded by mitochondrial cytochrome c release in the absence of a decrease in the mitochondrial membrane potential.
Toxicological sciences : an official journal of the Society of Toxicology 2005;86(1):92-100.
2005: Douglas C Jones; Christine L Duvauchelle; Aiko Ikegami; Christopher Olsen; Serrine S Lau; Rafael de la Torre; Terrence J Monks
Serotonergic neurotoxic metabolites of ecstasy identified in rat brain.
The Journal of pharmacology and experimental therapeutics 2005;313(1):422-31.
2005: Maria D Person; Daniel Mason; Daniel C Liebler; Terrence J Monks; Serrine S Lau
Alkylation of cytochrome c by (glutathion-S-yl)-1,4-benzoquinone and iodoacetamide demonstrates compound-dependent site specificity.
Chemical research in toxicology 2005;18(1):41-50.
2004: Erika L Abel; Robert P Lyon; Theo K Bammler; Christophe Verlinde; Serrine S Lau; Terrence J Monks; David Eaton
Estradiol metabolites as isoform-specific inhibitors of human glutathione S-transferases.
Chemico-biological interactions 2004;151(1):21-32.
2004: Zhe Jia; Maria D Person; Jing Dong; Jianjm Shen; Sean C Hensley; James L Stevens; Terrence J Monks; Serrine S Lau
Grp78 is essential for 11-deoxy-16,16-dimethyl PGE2-mediated cytoprotection in renal epithelial cells.
American journal of physiology. Renal physiology 2004;287(6):F1113-22.
2004: Jing Dong; Sampath Ramachandiran; Kulbhushan Tikoo; Zhe Jia; Serrine S Lau; Terrence J Monks
EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death.
American journal of physiology. Renal physiology 2004;287(5):F1049-58.
2004: Douglas C Jones; Serrine S Lau; Terrence J Monks
Thioether metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine inhibit human serotonin transporter (hSERT) function and simultaneously stimulate dopamine uptake into hSERT-expressing SK-N-MC cells.
The Journal of pharmacology and experimental therapeutics 2004;311(1):298-306.
2004: Jing Dong; Jeffrey I Everitt; Serrine S Lau; Terrence J Monks
Induction of ERK1/2 and histone H3 phosphorylation within the outer stripe of the outer medulla of the Eker rat by 2,3,5-tris-(glutathion-S-yl)hydroquinone.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(2):350-7.
2004: Terrence J Monks; Douglas C Jones; Fengju Bai; Serrine S Lau
The role of metabolism in 3,4-(+)-methylenedioxyamphetamine and 3,4-(+)-methylenedioxymethamphetamine (ecstasy) toxicity.
Therapeutic drug monitoring 2004;26(2):132-6.
2004: Hae-Seong Yoon; Sampath Ramachandiran; Mary Anne S Chacko; Terrence J Monks; Serrine S Lau
Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells.
American journal of physiology. Renal physiology 2004;286(2):F417-24.
2003: Sonal K Patel; Ning Ma; Terrence J Monks; Serrine S Lau
Changes in gene expression during chemical-induced nephrocarcinogenicity in the Eker rat.
Molecular carcinogenesis 2003;38(3):141-54.
2003: Maria D Person; Herng-Hsiang Lo; Kelly M Towndrow; Zhe Jia; Terrence J Monks; Serrine S Lau
Comparative identification of prostanoid inducible proteins by LC-ESI-MS/MS and MALDI-TOF mass spectrometry.
Chemical research in toxicology 2003;16(6):757-67.
2003: Maria D Person; Terrence J Monks; Serrine S Lau
An integrated approach to identifying chemically induced posttranslational modifications using comparative MALDI-MS and targeted HPLC-ESI-MS/MS.
Chemical research in toxicology 2003;16(5):598-608.
2003: Jun-Wei Liu; Jian-Jun Shen; Angela Tanzillo-Swarts; Bobby Bhatia; Carlos M Maldonado; Maria D Person; Serrine S Lau; Ding "Dean" G. Tang
Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration.
Oncogene 2003;22(10):1475-85.
2003: Samy Habib; Minh N Phan; Sonal K Patel; Donghui Li; Terrence J Monks; Serrine S Lau
Reduced constitutive 8-oxoguanine-DNA glycosylase expression and impaired induction following oxidative DNA damage in the tuberin deficient Eker rat.
Carcinogenesis 2003;24(3):573-82.
2003: Kelly M Towndrow; Zhe Jia; Herng-Hsiang Lo; Maria D Person; Terrence J Monks; Serrine S Lau
11-Deoxy,16,16-dimethyl prostaglandin E2 induces specific proteins in association with its ability to protect against oxidative stress.
Chemical research in toxicology 2003;16(3):312-9.
2002: Sampath Ramachandiran; Qihong Huang; Jing Dong; Serrine S Lau; Terrence J Monks
Mitogen-activated protein kinases contribute to reactive oxygen species-induced cell death in renal proximal tubule epithelial cells.
Chemical research in toxicology 2002;15(12):1635-42.
2002: Hae-Seong Yoon; Terrence J Monks; Jeffrey I Everitt; Cheryl Lyn Walker; Serrine S Lau
Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.
American journal of physiology. Renal physiology 2002;283(2):F262-70.
2001: Kulbhushan Tikoo; Serrine S Lau; Terrence J Monks
Histone H3 phosphorylation is coupled to poly-(ADP-ribosylation) during reactive oxygen species-induced cell death in renal proximal tubular epithelial cells.
Molecular pharmacology 2001;60(2):394-402.
2001: Fengju Bai; Douglas C Jones; Serrine S Lau; Terrence J Monks
Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase.
Chemical research in toxicology 2001;14(7):863-70.
2001: Thomas J Weber; Q Huang; Terrence J Monks; Serrine S Lau
Differential regulation of redox responsive transcription factors by the nephrocarcinogen 2,3,5-Tris(glutathion-S-yl)hydroquinone.
Chemical research in toxicology 2001;14(7):814-21.
2001: Hae-Seong Yoon; Terrence J Monks; Cheryl Lyn Walker; Serrine S Lau
Transformation of kidney epithelial cells by a quinol thioether via inactivation of the tuberous sclerosis-2 tumor suppressor gene.
Molecular carcinogenesis 2001;31(1):37-45.
2001: Serrine S Lau; Hae-Seong Yoon; Sonal K Patel; Jeffrey I Everitt; Cheryl Lyn Walker; Terrence J Monks
Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen.
Advances in experimental medicine and biology 2001;500():83-92.
2001: Terrence J Monks; Fengju Bai; R T Miller; Serrine S Lau
Serotonergic neurotoxicity of methylenedioxyamphetamine and methylenedioxymetamphetamine.
Advances in experimental medicine and biology 2001;500():397-406.
2001: Serrine S Lau; Terrence J Monks; Jeffrey I Everitt; Elena Kleymenova; Cheryl Lyn Walker
Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.
Chemical research in toxicology 2001;14(1):25-33.
2000: Shawn B Bratton; Serrine S Lau; Terrence J Monks
The putative benzene metabolite 2,3, 5-tris(glutathion-S-yl)hydroquinone depletes glutathione, stimulates sphingomyelin turnover, and induces apoptosis in HL-60 cells.
Chemical research in toxicology 2000;13(7):550-6.
2000: Kelly M Towndrow; J J Mertens; JK Jeong; Thomas J Weber; Terrence J Monks; Serrine S Lau
Stress- and growth-related gene expression are independent of chemical-induced prostaglandin E(2) synthesis in renal epithelial cells.
Chemical research in toxicology 2000;13(2):111-7.
2000: Thomas J Weber; Terrence J Monks; Serrine S Lau
DDM-PGE(2)-mediated cytoprotection in renal epithelial cells by a thromboxane A(2) receptor coupled to NF-kappaB.
American journal of physiology. Renal physiology 2000;278(2):F270-8.
1999: Fengju Bai; Serrine S Lau; Terrence J Monks
Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity.
Chemical research in toxicology 1999;12(12):1150-7.
1999: JK Jeong; Gerald N Wogan; Serrine S Lau; Terrence J Monks
Quinol-glutathione conjugate-induced mutation spectra in the supF gene replicated in human AD293 cells and bacterial MBL50 cells.
Cancer research 1999;59(15):3641-5.
1999: Qihong Huang; Serrine S Lau; Terrence J Monks
Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine.
The Biochemical journal 1999;341 ( Pt 1)():225-31.
1998: H E Kleiner; T W Jones; Terrence J Monks; Serrine S Lau
Immunochemical analysis of quinol-thioether-derived covalent protein adducts in rodent species sensitive and resistant to quinol-thioether-mediated nephrotoxicity.
Chemical research in toxicology 1998;11(11):1291-300.
1998: H E Kleiner; M I Rivera; N R Pumford; Terrence J Monks; Serrine S Lau
Immunochemical detection of quinol--thioether-derived protein adducts.
Chemical research in toxicology 1998;11(11):1283-90.
1998: Terrence J Monks; Serrine S Lau
The pharmacology and toxicology of polyphenolic-glutathione conjugates.
Annual review of pharmacology and toxicology 1998;38():229-55.
1998: M Butterworth; Serrine S Lau; Terrence J Monks
2-Hydroxy-4-glutathion-S-yl-17beta-estradiol and 2-hydroxy-1-glutathion-S-yl-17beta-estradiol produce oxidative stress and renal toxicity in an animal model of 17beta-estradiol-mediated nephrocarcinogenicity.
Carcinogenesis 1998;19(1):133-9.
1997: M M Peters; T W Jones; Terrence J Monks; Serrine S Lau
Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-(tris-glutathion-S-yl)hydroquinone.
Carcinogenesis 1997;18(12):2393-401.
1997: Terrence J Monks; Serrine S Lau
Biological reactivity of polyphenolic-glutathione conjugates.
Chemical research in toxicology 1997;10(12):1296-313.
1997: Thomas J Weber; Terrence J Monks; Serrine S Lau
PGE2-mediated cytoprotection in renal epithelial cells: evidence for a pharmacologically distinct receptor.
The American journal of physiology 1997;273(4 Pt 2):F507-15.
1997: Shawn B Bratton; Serrine S Lau; Terrence J Monks
Identification of quinol thioethers in bone marrow of hydroquinone/phenol-treated rats and mice and their potential role in benzene-mediated hematotoxicity.
Chemical research in toxicology 1997;10(8):859-65.
1997: JK Jeong; Erik Dybing; Erik J Søderlund; Gunnar Brunborg; Jørn Holme; Serrine S Lau; Terrence J Monks
DNA damage, gadd153 expression, and cytotoxicity in plateau-phase renal proximal tubular epithelial cells treated with a quinol thioether.
Archives of biochemistry and biophysics 1997;341(2):300-8.
1997: R T Miller; Serrine S Lau; Terrence J Monks
2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.
European journal of pharmacology 1997;323(2-3):173-80.
1997: JK Jeong; Qihong Huang; Serrine S Lau; Terrence J Monks
The response of renal tubular epithelial cells to physiologically and chemically induced growth arrest.
The Journal of biological chemistry 1997;272(11):7511-8.
1997: M Butterworth; Serrine S Lau; Terrence J Monks
Formation of catechol estrogen glutathione conjugates and gamma-glutamyl transpeptidase-dependent nephrotoxicity of 17beta-estradiol in the golden Syrian hamster.
Carcinogenesis 1997;18(3):561-7.
1996: JK Jeong; J L Stevens; Serrine S Lau; Terrence J Monks
Quinone thioether-mediated DNA damage, growth arrest, and gadd153 expression in renal proximal tubular epithelial cells.
Molecular pharmacology 1996;50(3):592-8.
1996: M Butterworth; Serrine S Lau; Terrence J Monks
17 beta-estradiol metabolism by hamster hepatic microsomes: comparison of catechol estrogen O-methylation with catechol estrogen oxidation and glutathione conjugation.
Chemical research in toxicology 1996;9(4):793-9.
1996: M Butterworth; Serrine S Lau; Terrence J Monks
17 beta-Estradiol metabolism by hamster hepatic microsomes. Implications for the catechol-O-methyl transferase-mediated detoxication of catechol estrogens.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(5):588-94.
1996: R T Miller; Serrine S Lau; Terrence J Monks
Effects of intracerebroventricular administration of 5-(glutathion-S-yl)-alpha-methyldopamine on brain dopamine, serotonin, and norepinephrine concentrations in male Sprague-Dawley rats.
Chemical research in toxicology 1996;9(2):457-65.
1996: M M Peters; M I Rivera; T W Jones; Terrence J Monks; Serrine S Lau
Glutathione conjugates of tert-butyl-hydroquinone, a metabolite of the urinary tract tumor promoter 3-tert-butyl-hydroxyanisole, are toxic to kidney and bladder.
Cancer research 1996;56(5):1006-11.
1996: M M Peters; Serrine S Lau; D Dulik; D Murphy; B van Ommen; Peter J van Bladeren; Terrence J Monks
Metabolism of tert-butylhydroquinone to S-substituted conjugates in the male Fischer 344 rat.
Chemical research in toxicology 1996;9(1):133-9.
1996: Serrine S Lau; M M Peters; H E Kleiner; P L Canales; Terrence J Monks
Linking the metabolism of hydroquinone to its nephrotoxicity and nephrocarcinogenicity.
Advances in experimental medicine and biology 1996;387():267-73.
1996: Terrence J Monks; M I Rivera; J J Mertens; M M Peters; Serrine S Lau
The kidney as a target for biological reactive metabolites: linking metabolism to toxicity.
Advances in experimental medicine and biology 1996;387():203-12.
1995: Serrine S Lau; H E Kleiner; Terrence J Monks
Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N-acetylation and N-deacetylation.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(10):1136-42.
1995: R T Miller; Serrine S Lau; Terrence J Monks
Metabolism of 5-(glutathion-S-yl)-alpha-methyldopamine following intracerebroventricular administration to male Sprague-Dawley rats.
Chemical research in toxicology 1995;8(5):634-41.
1995: J J Mertens; N W Gibson; Serrine S Lau; Terrence J Monks
Reactive oxygen species and DNA damage in 2-bromo-(glutathion-S-yl) hydroquinone-mediated cytotoxicity.
Archives of biochemistry and biophysics 1995;320(1):51-8.
1995: Serrine S Lau
Quinone-thioether-mediated nephrotoxicity.
Drug metabolism reviews 1995;27(1-2):125-41.
1994: B A Hill; K L Davison; D M Dulik; Terrence J Monks; Serrine S Lau
Metabolism of 2-(glutathion-S-yl)hydroquinone and 2,3,5- (triglutathion-S-yl)hydroquinone in the in situ perfused rat kidney: relationship to nephrotoxicity.
Toxicology and applied pharmacology 1994;129(1):121-32.
1994: M I Rivera; T W Jones; Serrine S Lau; Terrence J Monks
Early morphological and biochemical changes during 2-Br-(diglutathion-S-yl)hydroquinone-induced nephrotoxicity.
Toxicology and applied pharmacology 1994;128(2):239-50.
1994: Terrence J Monks; HH Lo; Serrine S Lau
Oxidation and acetylation as determinants of 2-bromocystein-S-ylhydroquinone-mediated nephrotoxicity.
Chemical research in toxicology 1994;7(4):495-502.
1994: M I Rivera; L M Hinojosa; B A Hill; Serrine S Lau; Terrence J Monks
Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
Drug metabolism and disposition: the biological fate of chemicals 1994;22(4):503-10.
1994: Terrence J Monks; Serrine S Lau
Glutathione conjugation as a mechanism for the transport of reactive metabolites.
Advances in pharmacology (San Diego, Calif.) 1994;27():183-210.
1993: B A Hill; H E Kleiner; E A Ryan; D M Dulik; Terrence J Monks; Serrine S Lau
Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy.
Chemical research in toxicology 1993;6(4):459-69.
1992: B A Hill; Terrence J Monks; Serrine S Lau
The effects of 2,3,5-(triglutathion-S-yl)hydroquinone on renal mitochondrial respiratory function in vivo and in vitro: possible role in cytotoxicity.
Toxicology and applied pharmacology 1992;117(2):165-71.
1992: Steven W Leslie; L M Brown; R D Trent; Y H Lee; J L Morris; T W Jones; Patrick K Randall; Serrine S Lau; Terrence J Monks
Stimulation of N-methyl-D-aspartate receptor-mediated calcium entry into dissociated neurons by reduced and oxidized glutathione.
Molecular pharmacology 1992;41(2):308-14.
1992: Terrence J Monks; Serrine S Lau
Toxicology of quinone-thioethers.
Critical reviews in toxicology 1992;22(5-6):243-70.
1991: Terrence J Monks; T W Jones; B A Hill; Serrine S Lau
Nephrotoxicity of 2-bromo-(cystein-S-yl) hydroquinone and 2-bromo-(N-acetyl-L-cystein-S-yl) hydroquinone thioethers.
Toxicology and applied pharmacology 1991;111(2):279-98.
1991: J J Mertens; J H Temmink; Peter J van Bladeren; T W Jones; HH Lo; Serrine S Lau; Terrence J Monks
Inhibition of gamma-glutamyl transpeptidase potentiates the nephrotoxicity of glutathione-conjugated chlorohydroquinones.
Toxicology and applied pharmacology 1991;110(1):45-60.
1991: Terrence J Monks; Serrine S Lau; J J Mertens; J H Temmink; Peter J van Bladeren
The nephrotoxicity of 2,5-dichloro-3-(glutathion-S-yl)-1,4-benzoquinone, and 2,5,6-trichloro-3-(glutathion-S-yl)-1,4-benzoquinone is potentiated by ascorbic acid and AT-125.
Advances in experimental medicine and biology 1991;283():767-9.
1991: B A Hill; HH Lo; Terrence J Monks; Serrine S Lau
The role of gamma-glutamyl transpeptidase in hydroquinone-glutathione conjugate mediated nephrotoxicity.
Advances in experimental medicine and biology 1991;283():749-51.
1991: Serrine S Lau; Terrence J Monks
Glutathione conjugation as a mechanism of targeting latent quinones to the kidney.
Advances in experimental medicine and biology 1991;283():457-64.
1990: Serrine S Lau; T W Jones; R Sioco; B A Hill; R K Pinon; Terrence J Monks
Species differences in renal gamma-glutamyl transpeptidase activity do not correlate with susceptibility to 2-bromo-(diglutathion-S-yl)-hydroquinone nephrotoxicity.
Toxicology 1990;64(3):291-311.
1990: Terrence J Monks; M W Anders; W Dekant; J L Stevens; Serrine S Lau; Peter J van Bladeren
Glutathione conjugate mediated toxicities.
Toxicology and applied pharmacology 1990;106(1):1-19.
1990: Terrence J Monks; Serrine S Lau
Nephrotoxicity of quinol/quinone-linked S-conjugates.
Toxicology letters 1990;53(1-2):59-67.
1990: J J Mertens; J G Sterck; Serrine S Lau; Terrence J Monks; Peter J van Bladeren; J H Temmink
Cytotoxicity of nephrotoxic glutathione-conjugated halohydroquinones.
Toxicology letters 1990;53(1-2):147-9.
1990: Terrence J Monks; R J Highet; Serrine S Lau
Oxidative cyclization, 1,4-benzothiazine formation and dimerization of 2-bromo-3-(glutathion-S-yl)hydroquinone.
Molecular pharmacology 1990;38(1):121-7.
1990: Serrine S Lau; T W Jones; R J Highet; B A Hill; Terrence J Monks
Differences in the localization and extent of the renal proximal tubular necrosis caused by mercapturic acid and glutathione conjugates of 1,4-naphthoquinone and menadione.
Toxicology and applied pharmacology 1990;104(2):334-50.
1990: Terrence J Monks; Serrine S Lau
Glutathione, gamma-glutamyl transpeptidase, and the mercapturic acid pathway as modulators of 2-bromohydroquinone oxidation.
Toxicology and applied pharmacology 1990;103(3):557-63.
1990: Serrine S Lau; Terrence J Monks
The in vivo disposition of 2-bromo-[14C]hydroquinone and the effect of gamma-glutamyl transpeptidase inhibition.
Toxicology and applied pharmacology 1990;103(1):121-32.
1988: Serrine S Lau; B A Hill; R J Highet; Terrence J Monks
Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution.
Molecular pharmacology 1988;34(6):829-36.
1988: Serrine S Lau; M G McMenamin; Terrence J Monks
Differential uptake of isomeric 2-bromohydroquinone-glutathione conjugates into kidney slices.
Biochemical and biophysical research communications 1988;152(1):223-30.