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Serrine Lau
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82
Monks, Terrence
6
Person, Maria
5
Jeong, JK
5
van Bladeren, Peter
4
Walker, Cheryl Lyn
4
Weber, Thomas
4
Yoon, Hae-Seong
4
Bai, Fengju
4
Dong, Jing
4
Everitt, Jeffrey
3
Bratton, Shawn
3
Huang, Qihong
3
Patel, Sonal
3
Jones, Douglas
3
Lo, Herng-Hsiang
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All Publications
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2009: Perfetti Ximena; O'Mathúna Brian; Pizarro Nieves; Cuyàs Elisabet; Khymenets Olha; Almeida Bruno; Pellegrini Manuela; Pichini Simona; Lau Serrine S; Monks Terrence J; Farré Magí; Pascual Jose Antonio; Joglar Jesús; de la Torre Rafael
Neurotoxic thioether adducts of 3,4-methylenedioxymethamphetamine identified in human urine after ecstasy ingestion.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(7):1448-55.
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2009: Labenski Matthew T; Fisher Ashley A; Lo Herng-Hsiang; Monks Terrence J; Lau Serrine S
Protein electrophile-binding motifs: lysine-rich proteins are preferential targets of quinones.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(6):1211-8.
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2008: Pizarro Nieves; de la Torre Rafael; Joglar Jesús; Okumura Noriko; Perfetti Ximena; Lau Serrine S; Monks Terrence J
Serotonergic neurotoxic thioether metabolites of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): synthesis, isolation, and characterization of diastereoisomers.
Chemical research in toxicology 2008;21(12):2272-9.
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2008: Erives Gladys V; Lau Serrine S; Monks Terrence J
Accumulation of neurotoxic thioether metabolites of 3,4-(+/-)-methylenedioxymethamphetamine in rat brain.
The Journal of pharmacology and experimental therapeutics 2008;324(1):284-91.
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2007: Fisher Ashley A; Labenski Matthew T; Malladi Srinivas; Gokhale Vijay; Bowen Martina E; Milleron Rania S; Bratton Shawn B; Monks Terrence J; Lau Serrine S
Quinone electrophiles selectively adduct "electrophile binding motifs" within cytochrome c.
Biochemistry 2007;46(39):11090-100.
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2007: Wozniak R J; Klimecki W T; Lau S S; Feinstein Y; Futscher B W
5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation.
Oncogene 2007;26(1):77-90.
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2006: Eblin K E; Bowen M E; Cromey D W; Bredfeldt T G; Mash E A; Lau S S; Gandolfi A J
Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture.
Toxicology and applied pharmacology 2006;217(1):7-14.
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2006: Monks Terrence J; Xie Ruiyu; Tikoo Kulbhushan; Lau Serrine S
Ros-induced histone modifications and their role in cell survival and cell death.
Drug metabolism reviews 2006;38(4):755-67.
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2005: Yang Mi Young; Lau Serrine S; Monks Terrence J
2,3,5-tris(Glutathion-S-yl)hydroquinone (TGHQ)-mediated apoptosis of human promyelocytic leukemia cells is preceded by mitochondrial cytochrome c release in the absence of a decrease in the mitochondrial membrane potential.
Toxicological sciences : an official journal of the Society of Toxicology 2005;86(1):92-100.
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2005: Jones Douglas C; Duvauchelle Christine; Ikegami Aiko; Olsen Christopher M; Lau Serrine S; de la Torre Rafael; Monks Terrence J
Serotonergic neurotoxic metabolites of ecstasy identified in rat brain.
The Journal of pharmacology and experimental therapeutics 2005;313(1):422-31.
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2005: Person Maria D; Mason Daniel E; Liebler Daniel C; Monks Terrence J; Lau Serrine S
Alkylation of cytochrome c by (glutathion-S-yl)-1,4-benzoquinone and iodoacetamide demonstrates compound-dependent site specificity.
Chemical research in toxicology 2005;18(1):41-50.
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2004: Abel Erika L; Lyon Robert P; Bammler Theodore K; Verlinde Christophe L M J; Lau Serrine S; Monks Terrence J; Eaton David L
Estradiol metabolites as isoform-specific inhibitors of human glutathione S-transferases.
Chemico-biological interactions 2004;151(1):21-32.
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2004: Jia Zhe; Person Maria D; Dong Jing; Shen Jianjm; Hensley Sean C; Stevens James L; Monks Terrence J; Lau Serrine S
Grp78 is essential for 11-deoxy-16,16-dimethyl PGE2-mediated cytoprotection in renal epithelial cells.
American journal of physiology. Renal physiology 2004;287(6):F1113-22.
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2004: Dong Jing; Ramachandiran Sampath; Tikoo Kulbhushan; Jia Zhe; Lau Serrine S; Monks Terrence J
EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death.
American journal of physiology. Renal physiology 2004;287(5):F1049-58.
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2004: Jones Douglas C; Lau Serrine S; Monks Terrence J
Thioether metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine inhibit human serotonin transporter (hSERT) function and simultaneously stimulate dopamine uptake into hSERT-expressing SK-N-MC cells.
The Journal of pharmacology and experimental therapeutics 2004;311(1):298-306.
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2004: Dong Jing; Everitt Jeffrey I; Lau Serrine S; Monks Terrence J
Induction of ERK1/2 and histone H3 phosphorylation within the outer stripe of the outer medulla of the Eker rat by 2,3,5-tris-(glutathion-S-yl)hydroquinone.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(2):350-7.
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2004: Monks Terrence J; Jones Douglas C; Bai Fengju; Lau Serrine S
The role of metabolism in 3,4-(+)-methylenedioxyamphetamine and 3,4-(+)-methylenedioxymethamphetamine (ecstasy) toxicity.
Therapeutic drug monitoring 2004;26(2):132-6.
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2004: Yoon Hae-Seong; Ramachandiran Sampath; Chacko Mary Anne S; Monks Terrence J; Lau Serrine S
Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells.
American journal of physiology. Renal physiology 2004;286(2):F417-24.
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2003: Patel Sonal K; Ma Ning; Monks Terrence J; Lau Serrine S
Changes in gene expression during chemical-induced nephrocarcinogenicity in the Eker rat.
Molecular carcinogenesis 2003;38(3):141-54.
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2003: Person Maria D; Lo Herng-Hsiang; Towndrow Kelly M; Jia Zhe; Monks Terrence J; Lau Serrine S
Comparative identification of prostanoid inducible proteins by LC-ESI-MS/MS and MALDI-TOF mass spectrometry.
Chemical research in toxicology 2003;16(6):757-67.
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2003: Person Maria D; Monks Terrence J; Lau Serrine S
An integrated approach to identifying chemically induced posttranslational modifications using comparative MALDI-MS and targeted HPLC-ESI-MS/MS.
Chemical research in toxicology 2003;16(5):598-608.
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2003: Habib Samy L; Phan Minh N; Patel Sonal K; Li Donghui; Monks Terrence J; Lau Serrine S
Reduced constitutive 8-oxoguanine-DNA glycosylase expression and impaired induction following oxidative DNA damage in the tuberin deficient Eker rat.
Carcinogenesis 2003;24(3):573-82.
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2003: Towndrow Kelly M; Jia Zhe; Lo Herng-Hsiang; Person Maria D; Monks Terrence J; Lau Serrine S
11-Deoxy,16,16-dimethyl prostaglandin E2 induces specific proteins in association with its ability to protect against oxidative stress.
Chemical research in toxicology 2003;16(3):312-9.
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2003: Liu Jun-Wei; Shen Jian-Jun; Tanzillo-Swarts Angela; Bhatia Bobby; Maldonado Carlos M; Person Maria D; Lau Serrine S; Tang Dean G
Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration.
Oncogene 2003;22(10):1475-85.
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2002: Ramachandiran Sampath; Huang Qihong; Dong Jing; Lau Serrine S; Monks Terrence J
Mitogen-activated protein kinases contribute to reactive oxygen species-induced cell death in renal proximal tubule epithelial cells.
Chemical research in toxicology 2002;15(12):1635-42.
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2002: Yoon Hae-Seong; Monks Terrence J; Everitt Jeffrey I; Walker Cheryl L; Lau Serrine S
Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.
American journal of physiology. Renal physiology 2002;283(2):F262-70.
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2001: Tikoo K; Lau S S; Monks T J
Histone H3 phosphorylation is coupled to poly-(ADP-ribosylation) during reactive oxygen species-induced cell death in renal proximal tubular epithelial cells.
Molecular pharmacology 2001;60(2):394-402.
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2001: Bai F; Jones D C; Lau S S; Monks T J
Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase.
Chemical research in toxicology 2001;14(7):863-70.
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2001: Weber T J; Huang Q; Monks T J; Lau S S
Differential regulation of redox responsive transcription factors by the nephrocarcinogen 2,3,5-Tris(glutathion-S-yl)hydroquinone.
Chemical research in toxicology 2001;14(7):814-21.
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2001: Yoon H S; Monks T J; Walker C L; Lau S S
Transformation of kidney epithelial cells by a quinol thioether via inactivation of the tuberous sclerosis-2 tumor suppressor gene.
Molecular carcinogenesis 2001;31(1):37-45.
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2001: Lau S S; Monks T J; Everitt J I; Kleymenova E; Walker C L
Carcinogenicity of a nephrotoxic metabolite of the "nongenotoxic" carcinogen hydroquinone.
Chemical research in toxicology 2001;14(1):25-33.
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2001: Lau S S; Yoon H S; Patel S K; Everitt J I; Walker C L; Monks T J
Mutagenicity and carcinogenicity of biological reactive intermediate's derived from a "non-genotoxic" carcinogen.
Advances in experimental medicine and biology 2001;500():83-92.
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2001: Monks T J; Bai F; Miller R T; Lau S S
Serotonergic neurotoxicity of methylenedioxyamphetamine and methylenedioxymetamphetamine.
Advances in experimental medicine and biology 2001;500():397-406.
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2000: Bratton S B; Lau S S; Monks T J
The putative benzene metabolite 2,3, 5-tris(glutathion-S-yl)hydroquinone depletes glutathione, stimulates sphingomyelin turnover, and induces apoptosis in HL-60 cells.
Chemical research in toxicology 2000;13(7):550-6.
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2000: Towndrow K M; Mertens J J; Jeong J K; Weber T J; Monks T J; Lau S S
Stress- and growth-related gene expression are independent of chemical-induced prostaglandin E(2) synthesis in renal epithelial cells.
Chemical research in toxicology 2000;13(2):111-7.
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2000: Weber T J; Monks T J; Lau S S
DDM-PGE(2)-mediated cytoprotection in renal epithelial cells by a thromboxane A(2) receptor coupled to NF-kappaB.
American journal of physiology. Renal physiology 2000;278(2):F270-8.
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1999: Bai F; Lau S S; Monks T J
Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity.
Chemical research in toxicology 1999;12(12):1150-7.
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1999: Jeong J K; Wogan G N; Lau S S; Monks T J
Quinol-glutathione conjugate-induced mutation spectra in the supF gene replicated in human AD293 cells and bacterial MBL50 cells.
Cancer research 1999;59(15):3641-5.
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1999: Huang Q; Lau S S; Monks T J
Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine.
The Biochemical journal 1999;341 ( Pt 1)():225-31.
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1998: Kleiner H E; Jones T W; Monks T J; Lau S S
Immunochemical analysis of quinol-thioether-derived covalent protein adducts in rodent species sensitive and resistant to quinol-thioether-mediated nephrotoxicity.
Chemical research in toxicology 1998;11(11):1291-300.
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1998: Kleiner H E; Rivera M I; Pumford N R; Monks T J; Lau S S
Immunochemical detection of quinol--thioether-derived protein adducts.
Chemical research in toxicology 1998;11(11):1283-90.
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1998: Butterworth M; Lau S S; Monks T J
2-Hydroxy-4-glutathion-S-yl-17beta-estradiol and 2-hydroxy-1-glutathion-S-yl-17beta-estradiol produce oxidative stress and renal toxicity in an animal model of 17beta-estradiol-mediated nephrocarcinogenicity.
Carcinogenesis 1998;19(1):133-9.
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1998: Monks T J; Lau S S
The pharmacology and toxicology of polyphenolic-glutathione conjugates.
Annual review of pharmacology and toxicology 1998;38():229-55.
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1997: Peters M M; Jones T W; Monks T J; Lau S S
Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-(tris-glutathion-S-yl)hydroquinone.
Carcinogenesis 1997;18(12):2393-401.
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1997: Monks T J; Lau S S
Biological reactivity of polyphenolic-glutathione conjugates.
Chemical research in toxicology 1997;10(12):1296-313.
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1997: Weber T J; Monks T J; Lau S S
PGE2-mediated cytoprotection in renal epithelial cells: evidence for a pharmacologically distinct receptor.
The American journal of physiology 1997;273(4 Pt 2):F507-15.
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1997: Bratton S B; Lau S S; Monks T J
Identification of quinol thioethers in bone marrow of hydroquinone/phenol-treated rats and mice and their potential role in benzene-mediated hematotoxicity.
Chemical research in toxicology 1997;10(8):859-65.
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1997: Jeong J K; Dybing E; Søderlund E; Brunborg G; Holme J A; Lau S S; Monks T J
DNA damage, gadd153 expression, and cytotoxicity in plateau-phase renal proximal tubular epithelial cells treated with a quinol thioether.
Archives of biochemistry and biophysics 1997;341(2):300-8.
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1997: Miller R T; Lau S S; Monks T J
2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.
European journal of pharmacology 1997;323(2-3):173-80.
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1997: Butterworth M; Lau S S; Monks T J
Formation of catechol estrogen glutathione conjugates and gamma-glutamyl transpeptidase-dependent nephrotoxicity of 17beta-estradiol in the golden Syrian hamster.
Carcinogenesis 1997;18(3):561-7.
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1997: Jeong J K; Huang Q; Lau S S; Monks T J
The response of renal tubular epithelial cells to physiologically and chemically induced growth arrest.
The Journal of biological chemistry 1997;272(11):7511-8.
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1996: Jeong J K; Stevens J L; Lau S S; Monks T J
Quinone thioether-mediated DNA damage, growth arrest, and gadd153 expression in renal proximal tubular epithelial cells.
Molecular pharmacology 1996;50(3):592-8.
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1996: Butterworth M; Lau S S; Monks T J
17 beta-estradiol metabolism by hamster hepatic microsomes: comparison of catechol estrogen O-methylation with catechol estrogen oxidation and glutathione conjugation.
Chemical research in toxicology 1996;9(4):793-9.
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1996: Butterworth M; Lau S S; Monks T J
17 beta-Estradiol metabolism by hamster hepatic microsomes. Implications for the catechol-O-methyl transferase-mediated detoxication of catechol estrogens.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(5):588-94.
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1996: Miller R T; Lau S S; Monks T J
Effects of intracerebroventricular administration of 5-(glutathion-S-yl)-alpha-methyldopamine on brain dopamine, serotonin, and norepinephrine concentrations in male Sprague-Dawley rats.
Chemical research in toxicology 1996;9(2):457-65.
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1996: Peters M M; Rivera M I; Jones T W; Monks T J; Lau S S
Glutathione conjugates of tert-butyl-hydroquinone, a metabolite of the urinary tract tumor promoter 3-tert-butyl-hydroxyanisole, are toxic to kidney and bladder.
Cancer research 1996;56(5):1006-11.
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1996: Peters M M; Lau S S; Dulik D; Murphy D; van Ommen B; van Bladeren P J; Monks T J
Metabolism of tert-butylhydroquinone to S-substituted conjugates in the male Fischer 344 rat.
Chemical research in toxicology 1996;9(1):133-9.
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1996: Lau S S; Peters M M; Kleiner H E; Canales P L; Monks T J
Linking the metabolism of hydroquinone to its nephrotoxicity and nephrocarcinogenicity.
Advances in experimental medicine and biology 1996;387():267-73.
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1996: Monks T J; Rivera M I; Mertens J J; Peters M M; Lau S S
The kidney as a target for biological reactive metabolites: linking metabolism to toxicity.
Advances in experimental medicine and biology 1996;387():203-12.
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1995: Lau S S; Kleiner H E; Monks T J
Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N-acetylation and N-deacetylation.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(10):1136-42.
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1995: Miller R T; Lau S S; Monks T J
Metabolism of 5-(glutathion-S-yl)-alpha-methyldopamine following intracerebroventricular administration to male Sprague-Dawley rats.
Chemical research in toxicology 1995;8(5):634-41.
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1995: Mertens J J; Gibson N W; Lau S S; Monks T J
Reactive oxygen species and DNA damage in 2-bromo-(glutathion-S-yl) hydroquinone-mediated cytotoxicity.
Archives of biochemistry and biophysics 1995;320(1):51-8.
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1995: Lau S S
Quinone-thioether-mediated nephrotoxicity.
Drug metabolism reviews 1995;27(1-2):125-41.
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1994: Hill B A; Davison K L; Dulik D M; Monks T J; Lau S S
Metabolism of 2-(glutathion-S-yl)hydroquinone and 2,3,5- (triglutathion-S-yl)hydroquinone in the in situ perfused rat kidney: relationship to nephrotoxicity.
Toxicology and applied pharmacology 1994;129(1):121-32.
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1994: Rivera M I; Jones T W; Lau S S; Monks T J
Early morphological and biochemical changes during 2-Br-(diglutathion-S-yl)hydroquinone-induced nephrotoxicity.
Toxicology and applied pharmacology 1994;128(2):239-50.
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1994: Monks T J; Lo H H; Lau S S
Oxidation and acetylation as determinants of 2-bromocystein-S-ylhydroquinone-mediated nephrotoxicity.
Chemical research in toxicology 1994;7(4):495-502.
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1994: Rivera M I; Hinojosa L M; Hill B A; Lau S S; Monks T J
Metabolism and toxicity of 2-bromo-(diglutathion-S-yl)-hydroquinone and 2-bromo-3-(glutathion-S-yl)hydroquinone in the in situ perfused rat kidney.
Drug metabolism and disposition: the biological fate of chemicals 1994;22(4):503-10.
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1994: Monks T J; Lau S S
Glutathione conjugation as a mechanism for the transport of reactive metabolites.
Advances in pharmacology (San Diego, Calif.) 1994;27():183-210.
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1993: Hill B A; Kleiner H E; Ryan E A; Dulik D M; Monks T J; Lau S S
Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy.
Chemical research in toxicology 1993;6(4):459-69.
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1992: Hill B A; Monks T J; Lau S S
The effects of 2,3,5-(triglutathion-S-yl)hydroquinone on renal mitochondrial respiratory function in vivo and in vitro: possible role in cytotoxicity.
Toxicology and applied pharmacology 1992;117(2):165-71.
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1992: Leslie S W; Brown L M; Trent R D; Lee Y H; Morris J L; Jones T W; Randall P K; Lau S S; Monks T J
Stimulation of N-methyl-D-aspartate receptor-mediated calcium entry into dissociated neurons by reduced and oxidized glutathione.
Molecular pharmacology 1992;41(2):308-14.
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1992: Monks T J; Lau S S
Toxicology of quinone-thioethers.
Critical reviews in toxicology 1992;22(5-6):243-70.
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1991: Monks T J; Jones T W; Hill B A; Lau S S
Nephrotoxicity of 2-bromo-(cystein-S-yl) hydroquinone and 2-bromo-(N-acetyl-L-cystein-S-yl) hydroquinone thioethers.
Toxicology and applied pharmacology 1991;111(2):279-98.
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1991: Mertens J J; Temmink J H; van Bladeren P J; Jones T W; Lo H H; Lau S S; Monks T J
Inhibition of gamma-glutamyl transpeptidase potentiates the nephrotoxicity of glutathione-conjugated chlorohydroquinones.
Toxicology and applied pharmacology 1991;110(1):45-60.
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1991: Monks T J; Lau S S; Mertens J J; Temmink J H; van Bladeren P J
The nephrotoxicity of 2,5-dichloro-3-(glutathion-S-yl)-1,4-benzoquinone, and 2,5,6-trichloro-3-(glutathion-S-yl)-1,4-benzoquinone is potentiated by ascorbic acid and AT-125.
Advances in experimental medicine and biology 1991;283():767-9.
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1991: Hill B A; Lo H H; Monks T J; Lau S S
The role of gamma-glutamyl transpeptidase in hydroquinone-glutathione conjugate mediated nephrotoxicity.
Advances in experimental medicine and biology 1991;283():749-51.
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1991: Lau S S; Monks T J
Glutathione conjugation as a mechanism of targeting latent quinones to the kidney.
Advances in experimental medicine and biology 1991;283():457-64.
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1990: Lau S S; Jones T W; Sioco R; Hill B A; Pinon R K; Monks T J
Species differences in renal gamma-glutamyl transpeptidase activity do not correlate with susceptibility to 2-bromo-(diglutathion-S-yl)-hydroquinone nephrotoxicity.
Toxicology 1990;64(3):291-311.
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1990: Monks T J; Anders M W; Dekant W; Stevens J L; Lau S S; van Bladeren P J
Glutathione conjugate mediated toxicities.
Toxicology and applied pharmacology 1990;106(1):1-19.
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1990: Monks T J; Lau S S
Nephrotoxicity of quinol/quinone-linked S-conjugates.
Toxicology letters 1990;53(1-2):59-67.
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1990: Mertens J J; Sterck J G; Lau S S; Monks T J; van Bladeren P J; Temmink J H
Cytotoxicity of nephrotoxic glutathione-conjugated halohydroquinones.
Toxicology letters 1990;53(1-2):147-9.
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1990: Monks T J; Highet R J; Lau S S
Oxidative cyclization, 1,4-benzothiazine formation and dimerization of 2-bromo-3-(glutathion-S-yl)hydroquinone.
Molecular pharmacology 1990;38(1):121-7.
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1990: Lau S S; Jones T W; Highet R J; Hill B A; Monks T J
Differences in the localization and extent of the renal proximal tubular necrosis caused by mercapturic acid and glutathione conjugates of 1,4-naphthoquinone and menadione.
Toxicology and applied pharmacology 1990;104(2):334-50.
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1990: Monks T J; Lau S S
Glutathione, gamma-glutamyl transpeptidase, and the mercapturic acid pathway as modulators of 2-bromohydroquinone oxidation.
Toxicology and applied pharmacology 1990;103(3):557-63.
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1990: Lau S S; Monks T J
The in vivo disposition of 2-bromo-[14C]hydroquinone and the effect of gamma-glutamyl transpeptidase inhibition.
Toxicology and applied pharmacology 1990;103(1):121-32.
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1988: Lau S S; Hill B A; Highet R J; Monks T J
Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution.
Molecular pharmacology 1988;34(6):829-36.
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1988: Lau S S; McMenamin M G; Monks T J
Differential uptake of isomeric 2-bromohydroquinone-glutathione conjugates into kidney slices.
Biochemical and biophysical research communications 1988;152(1):223-30.
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