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Yuen-Sum Lau

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TOP 3
Gaurav Patki; Yuen-Sum Lau
Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease.
Gaurav Patki; Yuen-Sum Lau
Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease.
Edward J Weinman; Rajatsubhra Biswas; Deborah Steplock; Peili Wang; Yuen-Sum Lau; Gary V Desir; Shirish Shenolikar
Increased renal dopamine and acute renal adaptation to a high-phosphate diet.

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All Publications

2011: Gaurav Patki; Yuen-Sum Lau
Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease.
Neuroscience letters 2011;505(3):268-72.
2011: Gaurav Patki; Yuen-Sum Lau
Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease.
Pharmacology, biochemistry, and behavior 2011;99(4):704-11.
2011: Edward J Weinman; Rajatsubhra Biswas; Deborah Steplock; Peili Wang; Yuen-Sum Lau; Gary V Desir; Shirish Shenolikar
Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
American journal of physiology. Renal physiology 2011;300(5):F1123-9.
2011: Yuen-Sum Lau; Gaurav Patki; Kaberi Das-Panja; Wei-Dong Le; S Omar Ahmad
Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson's disease with moderate neurodegeneration.
The European journal of neuroscience 2011;33(7):1264-74.
2009: Crisanto Escano; M Ines Armando; Xiaoyan Wang; Laureano Asico; Annabelle Pascua; Yu Yang; Zheng Wang; Yuen-Sum Lau; Pedro Jose
Renal dopaminergic defect in C57Bl/6J mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;297(6):R1660-9.
2009: Jennifer Barber-Singh; Byoung Boo Seo; Eiko Nakamaru-Ogiso; Yuen-Sum Lau; Akemi Matsuno-Yagi; Takao Yagi
Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorder.
Rejuvenation research 2009;12(4):259-67.
2009: S Omar Ahmad; Ji-Hyuk Park; Lisa Stenho-Bittel; Yuen-Sum Lau
Effects of endurance exercise on ventral tegmental area neurons in the chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and probenecid-treated mice.
Neuroscience letters 2009;450(2):102-5.
2009: Gaurav Patki; Yi Che; Yuen-Sum Lau
Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease.
Frontiers in aging neuroscience 2009;1():3.
2009: Konstantinos Pothakos; Max J Kurz; Yuen-Sum Lau
Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration.
BMC neuroscience 2009;10():6.
2008: Hewang Li; M Ines Armando; Peiying Yu; Crisanto Escano; Susette C Mueller; Laureano Asico; Annabelle Pascua; Quansheng Lu; Xiaoyan Wang; Van Anthony Villar; John E Jones; Zheng Wang; Ammasi Periasamy; Yuen-Sum Lau; Patricio Soares-da-Silva; Karen Creswell; Gaétan Guillemette; David R Sibley; Gilbert M Eisner; John J Gildea; Robin A Felder; Pedro Jose
Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells.
The Journal of clinical investigation 2008;118(6):2180-9.
2008: J Leigh Leasure; Anand Giddabasappa; Shawntay Chaney; Jerry E Johnson; Konstantinos Pothakos; Yuen-Sum Lau; Donald A Fox
Low-level human equivalent gestational lead exposure produces sex-specific motor and coordination abnormalities and late-onset obesity in year-old mice.
Environmental health perspectives 2008;116(3):355-61.
2008: Anees Ahmad Banday; Yuen-Sum Lau; Mustafa F Lokhandwala
Oxidative stress causes renal dopamine D1 receptor dysfunction and salt-sensitive hypertension in Sprague-Dawley rats.
Hypertension 2008;51(2):367-75.
2007: Max J Kurz; Konstantinos Pothakos; Sakeena Jamaluddin; Melissa Scott-Pandorf; Chris Arellano; Yuen-Sum Lau
A chronic mouse model of Parkinson's disease has a reduced gait pattern certainty.
Neuroscience letters 2007;429(1):39-42.
2007: M Al-Jarrah; K Pothakos; Lesya Novikova; Irina V Smirnova; Max J Kurz; Lisa Stehno-Bittel; Yuen-Sum Lau
Endurance exercise promotes cardiorespiratory rehabilitation without neurorestoration in the chronic mouse model of parkinsonism with severe neurodegeneration.
Neuroscience 2007;149(1):28-37.
2006: Lesya Novikova; Bryan L Garris; David R Garris; Yuen-Sum Lau
Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease.
Neuroscience 2006;140(1):67-76.
2005: Yuen-Sum Lau; Lesya Novikova; Christina Roels
MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact.
Neuroscience research 2005;52(4):371-8.
2005: David R Garris; Bryan L Garris; Lesya Novikova; Yuen-Sum Lau
Structural, metabolic and endocrine analysis of the diabetes (db/db) hypogonadal syndrome: relationship to hypophyseal hypercytolipidemia.
Cell and tissue research 2005;319(3):501-12.
2004: David R Garris; Lesya Novikova; Bryan L Garris; Yuen-Sum Lau
Hypercytolipidemia-induced nuclear lipoapoptosis: cytochemical analysis and integrated review of hypogonadal, diabetes-obesity syndrome-induced female reproductive axis disruption.
Metabolic syndrome and related disorders 2004;2(3):198-209.
2004: Bryan L Garris; Lesya Novikova; Yuen-Sum Lau; David R Garris
Hypophyseal lipoapoptosis: diabetes (db/db) mutation-associated cytolipidemia promotes pituitary cellular disruption and dysfunction.
Pituitary 2004;7(1):5-14.
2003: Yuen-Sum Lau; Elizabeth Petroske; Gloria E Meredith; Qiang Wang
Elevated neuronal nitric oxide synthase expression in chronic haloperidol-treated rats.
Neuropharmacology 2003;45(7):986-94.
2003: Yuen-Sum Lau
Measurement of dopamine uptake in neuronal cells and tissues.
Methods in molecular medicine 2003;79():465-71.
2003: Yuen-Sum Lau; Gloria E Meredith
From drugs of abuse to parkinsonism. The MPTP mouse model of Parkinson's disease.
Methods in molecular medicine 2003;79():103-16.
2003: Qiang Wang; Limin Mao; Yuen-Sum Lau
Adult neural stem/progenitor cells in the forebrain. Implications for psychostimulant dependence and medication.
Methods in molecular medicine 2003;79():33-42.
2002: Gloria E Meredith; Susan Totterdell; Elizabeth Petroske; K Santa Cruz; R C Callison; Yuen-Sum Lau
Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease.
Brain research 2002;956(1):156-65.
2002: Wallace D Berry; C Michael Moriarty; Yuen-Sum Lau
Lead attenuation of episodic growth hormone secretion in male rats.
International journal of toxicology 2002;21(2):93-8.
2001: Limin Mao; Yuen-Sum Lau; Elizabeth Petroske; Qiang Wang
Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration.
Brain research. Developmental brain research 2001;131(1-2):57-65.
2001: Qiang Wang; Yuen-Sum Lau
Dose-related alteration in nitric oxide synthase mRNA expression induced by amphetamine and the full D1 dopamine receptor agonist SKF-82958 in mouse striatum.
Neuroscience letters 2001;311(1):5-8.
2001: Elizabeth Petroske; Gloria E Meredith; S Callen; Susan Totterdell; Yuen-Sum Lau
Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment.
Neuroscience 2001;106(3):589-601.
2000: Limin Mao; Yuen-Sum Lau; Qiang Wang
Activation of group III metabotropic glutamate receptors inhibits basal and amphetamine-stimulated dopamine release in rat dorsal striatum: an in vivo microdialysis study.
European journal of pharmacology 2000;404(3):289-97.
1998: Yuen-Sum Lau; R Hao; Y K Fung; L S Fu; JF Bishop; Ronald F Pfeiffer; M M Mouradian
Modulation of nigrostriatal dopaminergic transmission by antisense oligodeoxynucleotide against brain-derived neurotrophic factor.
Neurochemical research 1998;23(4):525-32.
1997: Yuen-Sum Lau; Y K Fung; T M Anderson
Antagonistic effects of isofloxythepin on dopamine D1 and D2 receptors and behaviors in rats.
General pharmacology 1997;29(5):729-36.
1996: Y K Fung; M J Schmid; T M Anderson; Yuen-Sum Lau
Effects of nicotine withdrawal on central dopaminergic systems.
Pharmacology, biochemistry, and behavior 1996;53(3):635-40.
1995: R Hao; R B Norgren; Yuen-Sum Lau; Ronald F Pfeiffer
Cerebrospinal fluid of Parkinson's disease patients inhibits the growth and function of dopaminergic neurons in culture.
Neurology 1995;45(1):138-42.
1993: A M Camoratto; L M White; Yuen-Sum Lau; G O Ware; W D Berry; C M Moriarty
Effect of exposure to low level lead on growth and growth hormone release in rats.
Toxicology 1993;83(1-3):101-14.
1993: Yuen-Sum Lau; M M Mouradian
Protection against acute MPTP-induced dopamine depletion in mice by adenosine A1 agonist.
Journal of neurochemistry 1993;60(2):768-71.
1992: Y K Fung; Yuen-Sum Lau
Chronic effects of nicotine on mesolimbic dopaminergic system in rats.
Pharmacology, biochemistry, and behavior 1992;41(1):57-63.
1991: J A Wilson; Yuen-Sum Lau; J G Gleeson; J S Wilson
The action of MPTP on synaptic transmission is affected by changes in Ca2+ concentrations.
Brain research 1991;541(2):342-6.
1991: Y K Fung; Yuen-Sum Lau
Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions.
General pharmacology 1991;22(1):117-9.
1991: Yuen-Sum Lau; Y K Fung; K L Trobough; J R Cashman; J A Wilson
Depletion of striatal dopamine by the N-oxide of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Neurotoxicology 1991;12(2):189-99.
1991: Y K Fung; L A Fiske; Yuen-Sum Lau
Chronic administration of nicotine fails to alter the MPTP-induced neurotoxicity in mice.
General pharmacology 1991;22(4):669-72.
1991: Yuen-Sum Lau; A M Camoratto; L M White; C M Moriarty
Effect of lead on TRH and GRF binding in rat anterior pituitary membranes.
Toxicology 1991;68(2):169-79.
1990: Yuen-Sum Lau
Characteristics of Ca2+/calmodulin- and Ca2+/phosphatidylserine-stimulated phosphoproteins in rat striatum.
Neurochemical research 1990;15(3):265-72.
1990: Yuen-Sum Lau; K L Trobough; J M Crampton; J A Wilson
Effects of probenecid on striatal dopamine depletion in acute and long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice.
General pharmacology 1990;21(2):181-7.
1990: J A Wilson; T J Doyle; Yuen-Sum Lau
MPTP, MPDP+ and MPP+ cause decreases in dopamine content in mouse brain slices.
Neuroscience letters 1990;108(1-2):213-8.
1989: Y K Fung; Yuen-Sum Lau
Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems.
Pharmacology, biochemistry, and behavior 1989;33(1):1-6.
1989: Y K Fung; Yuen-Sum Lau
Effect of nicotine pretreatment on striatal dopaminergic system in rats.
Pharmacology, biochemistry, and behavior 1989;32(1):221-6.
1989: Y K Fung; J A Reed; Yuen-Sum Lau
Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats.
General pharmacology 1989;20(5):689-93.
1988: Y K Fung; Yuen-Sum Lau
Receptor mechanisms of nicotine-induced locomotor hyperactivity in chronic nicotine-treated rats.
European journal of pharmacology 1988;152(3):263-71.
1988: Yuen-Sum Lau; J M Crampton; J A Wilson
Urinary excretion of MPTP and its primary metabolites in mice.
Life sciences 1988;43(18):1459-64.
1988: J M Crampton; C E Runice; T J Doyle; Yuen-Sum Lau; J A Wilson
MPTP in mice: treatment, distribution and possible source of contamination.
Life sciences 1988;42(1):73-8.
1986: Y K Fung; Yuen-Sum Lau
Acute effect of nicotine on the striatal dopaminergic system in the rat.
The Journal of pharmacy and pharmacology 1986;38(12):920-2.
1986: Yuen-Sum Lau; Y K Fung
Pharmacological effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine receptor system.
Brain research 1986;369(1-2):311-5.