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Mary Laughlin

Research Profile

Anatomy

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Lymphocyte Activation

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Amin Alousi; Frederick R Appelbaum; Andrew Artz; Jonathan Benjamin; Steven M Devine; Mary Eapen; Fangyu Kan; Mary J Laughlin; Hillard M Lazarus; Jennifer Le-Rademacher; Jane Liesveld; Richard T Maziarz; Miguel-Angel Perales; Mitchell Sabloff; Rima M Saliba; Edmund K Waller; Richard E Champlin
Who is the better donor for older hematopoietic transplant recipients: an older-aged sibling or a young, matched unrelated volunteer?
Andromachi Scaradavou; John E Wagner; Juliet N Barker; Claudio G Brunstein; Nelson Chao; Corey Cutler; Colleen Delaney; Mary Eapen; Luis Isola; Fangyu Kan; Chatchada Karanes; Mary J Laughlin; Jennifer Le-Rademacher; Elizabeth J Shpall
Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia.
Hillard M Lazarus; F Liu; Scott R Sommers; N M Kaye; Tamila L Kindwall-Keller; Mary J Laughlin; Lisa M Arfons; S A Ataergin; Paul M Barr; Brenda W Cooper; Richard J Creger; Pingfu Fu; Stanton L Gerson; David Kaplan
Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: flow cytometric analysis of hematopoietic progenitor cell grafts.

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All Publications

2013: Amin Alousi; Frederick R Appelbaum; Andrew Artz; Jonathan Benjamin; Steven M Devine; Mary Eapen; Fangyu Kan; Mary J Laughlin; Hillard M Lazarus; Jennifer Le-Rademacher; Jane Liesveld; Richard T Maziarz; Miguel-Angel Perales; Mitchell Sabloff; Rima M Saliba; Edmund K Waller; Richard E Champlin
Who is the better donor for older hematopoietic transplant recipients: an older-aged sibling or a young, matched unrelated volunteer?
Blood 2013;121(13):2567-73.
2013: Andromachi Scaradavou; John E Wagner; Juliet N Barker; Claudio G Brunstein; Nelson Chao; Corey Cutler; Colleen Delaney; Mary Eapen; Luis Isola; Fangyu Kan; Chatchada Karanes; Mary J Laughlin; Jennifer Le-Rademacher; Elizabeth J Shpall
Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia.
Blood 2013;121(5):752-8.
2011: Hillard M Lazarus; F Liu; Scott R Sommers; N M Kaye; Tamila L Kindwall-Keller; Mary J Laughlin; Lisa M Arfons; S A Ataergin; Paul M Barr; Brenda W Cooper; Richard J Creger; Pingfu Fu; Stanton L Gerson; David Kaplan
Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: flow cytometric analysis of hematopoietic progenitor cell grafts.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(7):970-8.
2010: Mary Eapen; Vanderson Rocha; Guillermo Sanz; Andromachi Scaradavou; Mei-Jie Zhang; William Arcese; Anne Sirvent; Richard E Champlin; Nelson Chao; Adrian P Gee; Luis Isola; Mary J Laughlin; David I Marks; Samir Nabhan; Annalisa Ruggeri; Robert Soiffer; Mary M Horowitz; Eliane Gluckman; John E Wagner
Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis.
The lancet oncology 2010;11(7):653-60.
2010: Nicholas Greco; Mary J Laughlin
Umbilical cord blood stem cells for myocardial repair and regeneration.
Methods in molecular biology (Clifton, N.J.) 2010;660():29-52.
2010: Marcie R Finney; Laura R Fanning; Matthew E Joseph; Jonathan L Goldberg; Nicholas J Greco; Shyam Bhakta; Daniel G Winter; Margaret Forster; Paul E Scheid; Marwa Sabe; Vincent J Pompili; Mary J Laughlin
Umbilical cord blood-selected CD133(+) cells exhibit vasculogenic functionality in vitro and in vivo.
Cytotherapy 2010;12(1):67-78.
2009: R Patrick Weitzel; Mathew L Lesniewski; Peter Haviernik; Suzanne Kadereit; Patrick Leahy; Nicholas J Greco; Mary J Laughlin
microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4+ T cells.
Blood 2009;113(26):6648-57.
2009: Vivian Gama; Jose A Gomez; L D Mayo; Mark Jackson; David Danielpour; Kijoung Song; A L Haas; Mary J Laughlin; Shigemi Matsuyama
Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.
Cell death and differentiation 2009;16(5):758-69.
2008: William Tse; S L Zang; K D Bunting; Mary J Laughlin
Umbilical cord blood transplantation in adult myeloid leukemia.
Bone marrow transplantation 2008;41(5):465-72.
2008: Pingfu Fu; Willem J van Heeckeren; Punit D Wadhwa; D J Bajor; Richard J Creger; Z Xu; Brenda W Cooper; Mary J Laughlin; Stanton L Gerson; Omer N Koç; Hillard M Lazarus
Time-dependent effect of non-Hodgkin's lymphoma grade on disease-free survival of relapsed/refractory patients treated with high-dose chemotherapy plus autotransplantation.
Contemporary clinical trials 2008;29(2):157-64.
2008: Shyam Bhakta; Mary J Laughlin
New developments with umbilical cord blood.
Cytotherapy 2008;10(2):105-7.
2007: Willem J van Heeckeren; Laura R Fanning; Howard J Meyerson; Pingfu Fu; Hillard M Lazarus; Brenda W Cooper; William Tse; Tamila L Kindwall-Keller; Jennifer Jaroscak; Marcie R Finney; Robert M Fox; Luis A Solchaga; Margaret Forster; Richard J Creger; Mary J Laughlin
Influence of human leucocyte antigen disparity and graft lymphocytes on allogeneic engraftment and survival after umbilical cord blood transplant in adults.
British journal of haematology 2007;139(3):464-74.
2007: Jonathan L Goldberg; Mary J Laughlin; Vincent J Pompili
Umbilical cord blood stem cells: implications for cardiovascular regenerative medicine.
Journal of molecular and cellular cardiology 2007;42(5):912-20.
2007: J L Goldberg; Mary J Laughlin
UC blood hematopoietic stem cells and therapeutic angiogenesis.
Cytotherapy 2007;9(1):4-13.
2006: Pingfu Fu; R K Bagai; Howard J Meyerson; D Kane; Robert M Fox; Richard J Creger; Brenda W Cooper; Stanton L Gerson; Mary J Laughlin; Omer N Koc; Hillard M Lazarus
Pre-mobilization therapy blood CD34+ cell count predicts the likelihood of successful hematopoietic stem cell mobilization.
Bone marrow transplantation 2006;38(3):189-96.
2006: M Snell; C Chau; D Hendrix; R Fox; Katharine A Downes; Richard J Creger; Howard J Meyerson; Marilyn J Telen; Mary J Laughlin; Hillard M Lazarus; Roslyn Yomtovian
Lack of isohemagglutinin production following minor ABO incompatible unrelated HLA mismatched umbilical cord blood transplantation.
Bone marrow transplantation 2006;38(2):135-40.
2006: Meltem Yüksel; Elma D Baron; Melissa Camouse; Brenda W Cooper; Hillard M Lazarus; Stanton L Gerson; Mary J Laughlin; Kevin D Cooper; Anita Gilliam; Pingfu Fu; Seth Stevens; Omer N Koç
Peritransplant use of ultraviolet-B irradiation (UV-B) therapy is detrimental to allogeneic stem cell transplantation outcome.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(6):665-71.
2006: Shyam Bhakta; Nicholas J Greco; Marcie R Finney; Paul E Scheid; Robert D Hoffman; Matthew E Joseph; Jason J Banks; Mary J Laughlin; Vincent J Pompili
The safety of autologous intracoronary stem cell injections in a porcine model of chronic myocardial ischemia.
The Journal of invasive cardiology 2006;18(5):212-8.
2006: Marcie R Finney; Nicholas J Greco; Stephen E Haynesworth; Joseph M Martin; David P Hedrick; Jimmy Z Swan; Daniel G Winter; Suzanne Kadereit; Matthew E Joseph; Pingfu Fu; Vincent J Pompili; Mary J Laughlin
Direct comparison of umbilical cord blood versus bone marrow-derived endothelial precursor cells in mediating neovascularization in response to vascular ischemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(5):585-93.
2006: Mary J Laughlin
Unrelated cord blood allogeneic stem cell transplantation for MDS.
Leukemia & lymphoma 2006;47(4):569-70.
2006: Pingfu Fu; Mary J Laughlin; Heping Zhang
Comparison of survival times in a transplant study of hematologic disorders.
Contemporary clinical trials 2006;27(2):174-82.
2006: Willem J van Heeckeren; Jennifer Vollweiler; Pingfu Fu; Brenda W Cooper; Howard J Meyerson; Hillard M Lazarus; Alexandra Simic; Mary J Laughlin; Stanton L Gerson; Omer N Koç
Randomised comparison of two B-cell purging protocols for patients with B-cell non-Hodgkin lymphoma: in vivo purging with rituximab versus ex vivo purging with CliniMACS CD34 cell enrichment device.
British journal of haematology 2006;132(1):42-55.
2005: Thomas O Kleen; Suzanne Kadereit; Laura R Fanning; Jennifer Jaroscak; Pingfu Fu; Howard J Meyerson; Lara Kulchycki; Laura F Slivka; Margaret M Kozik; Magdalena Tary-Lehmann; Mary J Laughlin
Recipient-specific tolerance after HLA-mismatched umbilical cord blood stem cell transplantation.
Transplantation 2005;80(9):1316-22.
2005: Hillard M Lazarus; Omer N Koc; Steven M Devine; Peter Curtin; Richard T Maziarz; H Kent Holland; Elizabeth J Shpall; Philip McCarthy; Kerry Atkinson; Brenda W Cooper; Stanton L Gerson; Mary J Laughlin; Fausto R Loberiza; Annemarie Moseley; Andrea Bacigalupo
Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(5):389-98.
2005: Punit D Wadhwa; Pingfu Fu; Omer N Koc; Brenda W Cooper; Robert M Fox; Richard J Creger; David L Bajor; Teja Bedi; Mary J Laughlin; Jennifer Payne; Stanton L Gerson; Hillard M Lazarus
High-dose carmustine, etoposide, and cisplatin for autologous stem cell transplantation with or without involved-field radiation for relapsed/refractory lymphoma: an effective regimen with low morbidity and mortality.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(1):13-22.
2004: Mary J Laughlin; Mary Eapen; Pablo Rubinstein; John E Wagner; Mei-Jei Zhang; Richard E Champlin; Cladd E Stevens; Juliet N Barker; Robert P Gale; Hillard M Lazarus; David I Marks; Jon van Rood; Andromachi Scaradavou; Mary M Horowitz
Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia.
The New England journal of medicine 2004;351(22):2265-75.
2004: Basabi Maitra; Emese Szekely; K Gjini; Mary J Laughlin; J Dennis; Stephen E Haynesworth; Omer N Koç
Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation.
Bone marrow transplantation 2004;33(6):597-604.
2004: Nashaat S Hamza; Michelle V Lisgaris; Gopala K Yadavalli; Laura Nadeau; Robert Fox; Pingfu Fu; Hillard M Lazarus; Omer N Koc; Robert A Salata; Mary J Laughlin
Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults.
British journal of haematology 2004;124(4):488-98.
2003: Beth A Kaminski; Suzanne Kadereit; Robin E Miller; Patrick Leahy; Kevin R Stein; David A Topa; Tomas Radivoyevitch; Martina L Veigl; Mary J Laughlin
Reduced expression of NFAT-associated genes in UCB versus adult CD4+ T lymphocytes during primary stimulation.
Blood 2003;102(13):4608-17.
2003: Suzanne Kadereit; Gwendolyn R Junge; Thomas O Kleen; Margaret M Kozik; Beth A Kaminski; Kathleen Daum-Woods; Pingfu Fu; Magdalena Tary-Lehmann; Mary J Laughlin
Deficient IFN-gamma expression in umbilical cord blood (UCB) T cells can be rescued by IFN-gamma-mediated increase in NFATc2 expression.
Journal of clinical immunology 2003;23(6):485-97.
2003: John E Levine; Richard E Harris; Fausto R Loberiza; James O Armitage; Julie M Vose; Koen van Besien; Hillard M Lazarus; Mary M Horowitz; Asad Bashey; Brian J Bolwell; Linda J Burns; Mitchell S Cairo; Richard E Champlin; Cesar O Freytes; John Gibson; Steve C Goldstein; Mary J Laughlin; John Lister; David I Marks; Richard T Maziarz; Alan Marshall Miller; Gustavo A Milone; Santiago Pavlovsky; Andrew L Pecora; J Douglas Rizzo; Gary Schiller; Harry C Schouten; Mei-Jie Zhang
A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma.
Blood 2003;101(7):2476-82.
2003: Punit D Wadhwa; Hillard M Lazarus; Omer N Koc; Jennifer Jaroscak; David Woo; Cladd E Stevens; Pablo Rubinstein; Mary J Laughlin
Hematopoietic recovery after unrelated umbilical cord-blood allogeneic transplantation in adults treated with in vivo stem cell factor (R-MetHuSCF) and filgrastim administration.
Leukemia research 2003;27(3):215-20.
2002: Robin E Miller; John D Fayen; Shaden F Mohammad; Kevin Stein; Suzanne Kadereit; Kathleen Daum Woods; R Michael Sramkoski; James Jacobberger; Dennis Templeton; susan shurin; Mary J Laughlin
Reduced CTLA-4 protein and messenger RNA expression in umbilical cord blood T lymphocytes.
Experimental hematology 2002;30(7):738-44.
2002: David A Rizzieri; Adam J Bass; Gary Rosner; Jon P Gockerman; Carlos M DeCastro; William P Petros; David J Adams; Mary J Laughlin; Patti Davis; Traci Foster; Robert Jacobson; Herbert I Hurwitz; Joseph O Moore
Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(3):674-9.
2002: Suzanne Kadereit; Linda S Deeds; Stephen E Haynesworth; Omer N Koc; Margaret M Kozik; Emese Szekely; Kathleen Daum-Woods; Glenn W Goetchius; Pingfu Fu; Lisbeth A Welniak; William Murphy; Mary J Laughlin
Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer.
Stem cells (Dayton, Ohio) 2002;20(6):573-82.
2001: Suzanne Kadereit; Margaret M Kozik; G R Junge; Robin E Miller; L F Slivka; L S Bos; Kathleen Daum-Woods; R Michael Sramkoski; James Jacobberger; Mary J Laughlin
Cyclosporin A effects during primary and secondary activation of human umbilical cord blood T lymphocytes.
Experimental hematology 2001;29(7):903-9.
2001: Mary J Laughlin; Juliet N Barker; B Bambach; Omer N Koc; David A Rizzieri; John E Wagner; Stanton L Gerson; Hillard M Lazarus; Mitchell S Cairo; Cladd E Stevens; Pablo Rubinstein; Joanne Kurtzberg
Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors.
The New England journal of medicine 2001;344(24):1815-22.
2001: Mary J Laughlin
Umbilical cord blood for allogeneic transplantation in children and adults.
Bone marrow transplantation 2001;27(1):1-6.
2000: Martin S Tallman; Philip Rowlings; Gustavo A Milone; Mei-Jie Zhang; Waleska S Perez; Daniel Weisdorf; Armand Keating; Robert Peter Gale; R B Geller; Mary J Laughlin; Hillard M Lazarus; S M Luger; Philip L McCarthy; J M Rowe; RA Saez; MR Vowels; Mary M Horowitz
Effect of postremission chemotherapy before human leukocyte antigen-identical sibling transplantation for acute myelogenous leukemia in first complete remission.
Blood 2000;96(4):1254-8.
1999: Suzanne Kadereit; S F Mohammad; Robin E Miller; K D Woods; C D Listrom; Karen P McKinnon; A Alali; L S Bos; M L Iacobucci; M R Sramkoski; James Jacobberger; Mary J Laughlin
Reduced NFAT1 protein expression in human umbilical cord blood T lymphocytes.
Blood 1999;94(9):3101-7.
1998: Mark Graham II; Barbara L Asselin; James E Herndon; J R Casey; S Chaffee; Gilbert Ciocci; Charles Daeschner; A R Davis; Stuart Gold; Edward C Halperin; Mary J Laughlin; Paul L Martin; J F Olson; Joanne Kurtzberg
Toxicity, pharmacology and feasibility of administration of PEG-L-asparaginase as consolidation therapy in patients undergoing bone marrow transplantation for acute lymphoblastic leukemia.
Bone marrow transplantation 1998;21(9):879-85.
1998: Mary J Laughlin; David A Rizzieri; C A Smith; Joseph O Moore; S Lilly; Dean McGaughey; P Martin; Carmelita Carrier; Cladd E Stevens; Pablo Rubinstein; R Buckley; Joanne Kurtzberg
Hematologic engraftment and reconstitution of immune function post unrelated placental cord blood transplant in an adult with acute lymphocytic leukemia.
Leukemia research 1998;22(3):215-9.
1998: Mary J Laughlin; Dean McGaughey; J R Crews; Nelson J Chao; David A Rizzieri; Maureen Ross; Jon P Gockerman; Constance Cirrincione; Donald Berry; L Mills; P Defusco; S LeGrand; William P Peters; James J Vredenburgh
Secondary myelodysplasia and acute leukemia in breast cancer patients after autologous bone marrow transplant.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(3):1008-12.
1997: M L Graham; James E Herndon; J R Casey; S Chaffee; Gilbert Ciocci; J P Krischer; Joanne Kurtzberg; Mary J Laughlin; DC Longee; J F Olson; N Paleologus; C N Pennington; Henry S Friedman
High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):1814-23.
1993: Mary J Laughlin; G Kirkpatrick; N Sabiston; W Peters; Joanne Kurtzberg
Hematopoietic recovery following high-dose combined alkylating-agent chemotherapy and autologous bone marrow support in patients in phase-I clinical trials of colony-stimulating factors: G-CSF, GM-CSF, IL-1, IL-2, M-CSF.
Annals of hematology 1993;67(6):267-76.