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Lisbeth Laursen

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Ervinas Gaidamauskas; Claus Gyrup; Lisbeth S Laursen; Michael T Overgaard; Henning B Boldt; Vivien R Schack; Claus Oxvig
IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.
Lisbeth S Laursen; Colin W Chan; Charles Ffrench-Constant
Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.
Jakob H Mikkelsen; Claus Gyrup; Peter Kristensen; Michael T Overgaard; Christine B Poulsen; Lisbeth S Laursen; Claus Oxvig
Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.

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All Publications

2013: Ervinas Gaidamauskas; Claus Gyrup; Lisbeth S Laursen; Michael T Overgaard; Henning B Boldt; Vivien R Schack; Claus Oxvig
IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.
Biochimica et biophysica acta 2013;1830(3):2701-9.
2011: Lisbeth S Laursen; Colin W Chan; Charles Ffrench-Constant
Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.
The Journal of cell biology 2011;192(5):797-811.
2008: Jakob H Mikkelsen; Claus Gyrup; Peter Kristensen; Michael T Overgaard; Christine B Poulsen; Lisbeth S Laursen; Claus Oxvig
Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.
The Journal of biological chemistry 2008;283(24):16772-80.
2008: Hiroyasu Kamei; Ling Lu; Shuang Jiao; Yun Li; Claus Gyrup; Lisbeth S Laursen; Claus Oxvig; Jianfeng Zhou; Cunming Duan
Duplication and diversification of the hypoxia-inducible IGFBP-1 gene in zebrafish.
PloS one 2008;3(8):e3091.
2007: Lisbeth S Laursen; Charles Ffrench-Constant
Adhesion molecules in the regulation of CNS myelination.
Neuron glia biology 2007;3(4):367-75.
2007: Lisbeth S Laursen; Kasper Kjaer-Sorensen; Mikkel H Andersen; Claus Oxvig
Regulation of insulin-like growth factor (IGF) bioactivity by sequential proteolytic cleavage of IGF binding protein-4 and -5.
Molecular endocrinology (Baltimore, Md.) 2007;21(5):1246-57.
2007: Simon Glerup; Søren Kløverpris; Lisbeth S Laursen; Frederik Dagnaes-Hansen; Steffen Thiel; Cheryl A Conover; Claus Oxvig
Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor.
The Journal of biological chemistry 2007;282(3):1769-78.
2005: Lisbeth S Laursen; Claus Oxvig
Real-time measurement in living cells of insulin-like growth factor activity using bioluminescence resonance energy transfer.
Biochemical pharmacology 2005;69(12):1723-32.
2004: Kathrin Weyer; Michael T Overgaard; Lisbeth S Laursen; Claus G Nielsen; Alexander Schmitz; Michael Christiansen; Lars Sottrup-Jensen; Linda C Giudice; Claus Oxvig
Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module.
European journal of biochemistry / FEBS 2004;271(8):1525-35.
2002: Lisbeth S Laursen; Michael T Overgaard; Kathrin Weyer; Henning B Boldt; Peter Ebbesen; Michael Christiansen; Lars Sottrup-Jensen; Linda C Giudice; Claus Oxvig
Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.
The Journal of biological chemistry 2002;277(49):47225-34.
2002: Lisbeth S Laursen; Michael T Overgaard; Claus G Nielsen; Henning B Boldt; Kathrin H Hopmann; Cheryl A Conover; Lars Sottrup-Jensen; Linda C Giudice; Claus Oxvig
Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis.
The Biochemical journal 2002;367(Pt 1):31-40.
2002: Rikke Søe; Michael T Overgaard; Anni R Thomsen; Lisbeth S Laursen; Inger M Olsen; Lars Sottrup-Jensen; Jesper Haaning; Linda C Giudice; Cheryl A Conover; Claus Oxvig
Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity.
European journal of biochemistry / FEBS 2002;269(8):2247-56.
2001: Henning B Boldt; Michael T Overgaard; Lisbeth S Laursen; Kathrin Weyer; Lars Sottrup-Jensen; Claus Oxvig
Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.
The Biochemical journal 2001;358(Pt 2):359-67.
2001: Lisbeth S Laursen; Michael T Overgaard; Rikke Søe; Henning B Boldt; Lars Sottrup-Jensen; Linda C Giudice; Cheryl A Conover; Claus Oxvig
Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A.
FEBS letters 2001;504(1-2):36-40.
2001: Michael T Overgaard; Henning B Boldt; Lisbeth S Laursen; Lars Sottrup-Jensen; Cheryl A Conover; Claus Oxvig
Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase.
The Journal of biological chemistry 2001;276(24):21849-53.
2000: Michael T Overgaard; Jesper Haaning; Henning B Boldt; Inger M Olsen; Lisbeth S Laursen; Michael Christiansen; Gerald J Gleich; Lars Sottrup-Jensen; Cheryl A Conover; Claus Oxvig
Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor.
The Journal of biological chemistry 2000;275(40):31128-33.
1998: Jørgen Riis Jepsen; Lisbeth S Laursen
Recent changes in Danish law on drugs and drug offences.
European addiction research 1998;4(3):113-27.