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Mark Lautens

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Phenomena

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Molecular Structure

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Co-Publications
Name
9
Fagnou, Keith
8
Fang, Yuan-Qing
8
Alberico, Dino
6
Rudolph, Alena
6
Dockendorff, Chris
5
Scott, Mark
5
Thansandote, Praew
5
Maddess, Matthew
5
Mariampillai, Brian
4
Mancuso, John
4
Paquin, Jean-François
3
Han, Wooseok
3
Hiebert, Sheldon
3
Hulcoop, David
3
Laleu, Benoît

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Publications

TOP 3
Webster Robert; Lautens Mark
Conformational effects in diastereoselective aryne Diels-Alder reactions: synthesis of benzo-fused [2.2.1] heterobicycles.
Newman Stephen G; Aureggi Valentina; Bryan Christopher S; Lautens Mark
Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles.
Thansandote Praew; Lautens Mark
Construction of nitrogen-containing heterocycles by C-H bond functionalization.

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All Publications

2009: Webster Robert; Lautens Mark
Conformational effects in diastereoselective aryne Diels-Alder reactions: synthesis of benzo-fused [2.2.1] heterobicycles.
Organic letters 2009;11(20):4688-91.
2009: Newman Stephen G; Aureggi Valentina; Bryan Christopher S; Lautens Mark
Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles.
Chemical communications (Cambridge, England) 2009;(35):5236-8.
2009: Thansandote Praew; Lautens Mark
Construction of nitrogen-containing heterocycles by C-H bond functionalization.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(24):5874-83.
2009: Chai David I; Lautens Mark
Tandem Pd-catalyzed double C-C bond formation: effect of water.
The Journal of organic chemistry 2009;74(8):3054-61.
2009: Tseng Nai-Wen; Lautens Mark
Rhodium-catalyzed vinylcyclopropanation/cyclopentenation of strained alkenes via a sequential carborhodation process.
The Journal of organic chemistry 2009;74(6):2521-6.
2009: Martins Andrew; Lemouzy Sébastien; Lautens Mark
Bifunctional reactivity of cu(i): sequential ring opening/n-arylation.
Organic letters 2009;11(5):1191.
2009: Isono Naohiro; Lautens Mark
Rhodium(I)-catalyzed cyclization reaction of o-alkynyl phenols and anilines. Domino approach to 2,3-disubstituted benzofurans and indoles.
Organic letters 2009;11(6):1329-31.
2009: Thansandote Praew; Gouliaras Christina; Turcotte-Savard Marc-Olivier; Lautens Mark
A rapid approach to the synthesis of highly functionalized tetrahydroisoquinolines.
The Journal of organic chemistry 2009;74(4):1791-3.
2009: Dockendorff Chris; Jin Shujuan; Olsen Madeline; Lautens Mark; Coupal Martin; Hodzic Lejla; Spear Nathan; Payza Kemal; Walpole Christopher; Tomaszewski Miroslaw J
Discovery of mu-opioid selective ligands derived from 1-aminotetralin scaffolds made via metal-catalyzed ring-opening reactions.
Bioorganic & medicinal chemistry letters 2009;19(4):1228-32.
2009: Thansandote Praew; Hulcoop David G; Langer Michael; Lautens Mark
Palladium-catalyzed annulation of haloanilines and halobenzamides using norbornadiene as an acetylene synthon: a route to functionalized indolines, isoquinolinones, and indoles.
The Journal of organic chemistry 2009;74(4):1673-8.
2009: Tseng Nai-Wen; Lautens Mark
Application of a rhodium-catalyzed addition/cyclization sequence toward the synthesis of polycyclic heteroaromatics.
The Journal of organic chemistry 2009;74(4):1809-11.
2009: Webster Robert; Böing Christian; Lautens Mark
Reagent-controlled regiodivergent resolution of unsymmetrical oxabicyclic alkenes using a cationic rhodium catalyst.
Journal of the American Chemical Society 2009;131(2):444-5.
2009: Martins Andrew; Lemouzy Sébastien; Lautens Mark
Bifunctional reactivity of Cu(I): sequential ring opening/N-arylation.
Organic letters 2009;11(1):181-3.
2009: Rudolph Alena; Rackelmann Nils; Turcotte-Savard Marc-Olivier; Lautens Mark
Application of secondary alkyl halides to a domino aryl alkylation reaction for the synthesis of aromatic heterocycles.
The Journal of organic chemistry 2009;74(1):289-97.
2009: Bryan Christopher S; Braunger Julia A; Lautens Mark
Efficient synthesis of benzothiophenes by an unusual palladium-catalyzed vinylic C-S coupling.
Angewandte Chemie (International ed. in English) 2009;48(38):7064-8.
2009: Candito David A; Lautens Mark
Palladium-catalyzed domino direct arylation/N-arylation: convenient synthesis of phenanthridines.
Angewandte Chemie (International ed. in English) 2009;48(36):6713-6.
2009: Rudolph Alena; Lautens Mark
Secondary alkyl halides in transition-metal-catalyzed cross-coupling reactions.
Angewandte Chemie (International ed. in English) 2009;48(15):2656-70.
2009: Zhao Ya-Bin; Mariampillai Brian; Candito David A; Laleu Benoît; Li Mengzhou; Lautens Mark
Exploiting the divergent reactivity of aryl-palladium intermediates for the rapid assembly of fluorene and phenanthrene derivatives.
Angewandte Chemie (International ed. in English) 2009;48(10):1849-52.
2009: Gericke Kersten M; Chai David I; Bieler Nikolas; Lautens Mark
The norbornene shuttle: multicomponent domino synthesis of tetrasubstituted helical alkenes through multiple C--H functionalization.
Angewandte Chemie (International ed. in English) 2009;48(8):1447-51.
2008: Laleu Benoît; Lautens Mark
Synthesis of annulated 2H-indazoles and 1,2,3- and 1,2,4-triazoles via a one-pot palladium-catalyzed alkylation/direct arylation reaction.
The Journal of organic chemistry 2008;73(22):9164-7.
2008: Martins Andrew; Lautens Mark
A palladium-catalyzed approach to polycyclic sulfur heterocycles.
The Journal of organic chemistry 2008;73(22):8705-10.
2008: Scott Mark E; Lautens Mark
Synthesis of highly functionalized pyrrolidines via a selective iodide-mediated ring expansion of methylenecyclopropyl amides.
The Journal of organic chemistry 2008;73(21):8154-62.
2008: Martins Andrew; Lautens Mark
Aromatic ortho-benzylation reveals an unexpected reductant.
Organic letters 2008;10(21):5095-7.
2008: Bryan Christopher S; Lautens Mark
Silver-promoted domino Pd-catalyzed amination/direct arylation: access to polycyclic heteroaromatics.
Organic letters 2008;10(20):4633-6.
2008: Martins Andrew; Lautens Mark
A simple, cost-effective method for the regioselective deuteration of anilines.
Organic letters 2008;10(19):4351-3.
2008: Blaszykowski Christophe; Aktoudianakis Evangelos; Alberico Dino; Bressy Cyril; Hulcoop David G; Jafarpour Farnaz; Joushaghani Arash; Laleu Benoît; Lautens Mark
A palladium-catalyzed alkylation/direct arylation synthesis of nitrogen-containing heterocycles.
The Journal of organic chemistry 2008;73(5):1888-97.
2008: Fang Yuan-Qing; Lautens Mark
A highly selective tandem cross-coupling of gem-dihaloolefins for a modular, efficient synthesis of highly functionalized indoles.
The Journal of organic chemistry 2008;73(2):538-49.
2008: Menard Frederic; Lautens Mark
Chemodivergence in enantioselective desymmetrization of diazabicycles: ring-opening versus reductive arylation.
Angewandte Chemie (International ed. in English) 2008;47(11):2085-8.
2008: Fleming Matthew J; McManus Helen A; Rudolph Alena; Chan Walter H; Ruiz Jérémy; Dockendorff Chris; Lautens Mark
Concise enantioselective total syntheses of (+)-homochelidonine, (+)-chelamidine, (+)-chelidonine, (+)-chelamine and (+)-norchelidonine by a Pd II-catalyzed ring-opening strategy.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(7):2112-24.
2007: Menard Frederic; Weise Christian Frederik; Lautens Mark
Rh(I)-catalyzed carbonylative ring opening of diazabicycles with acyl anion equivalents.
Organic letters 2007;9(26):5365-7.
2007: Mariampillai Brian; Alliot Julien; Li Mengzhou; Lautens Mark
A convergent synthesis of polysubstituted aromatic nitriles via palladium-catalyzed C-H functionalization.
Journal of the American Chemical Society 2007;129(49):15372-9.
2007: Thansandote Praew; Raemy Manuel; Rudolph Alena; Lautens Mark
Synthesis of benzannulated N-heterocycles by a palladium-catalyzed C-C/C-N coupling of bromoalkylamines.
Organic letters 2007;9(25):5255-8.
2007: Nagamochi Masatoshi; Fang Yuan-Qing; Lautens Mark
A general and practical method of alkynyl indole and benzofuran synthesis via tandem Cu- and Pd-catalyzed cross-couplings.
Organic letters 2007;9(15):2955-8.
2007: Fang Yuan-Qing; Yuen Josephine; Lautens Mark
A general modular method of azaindole and thienopyrrole synthesis via Pd-catalyzed tandem couplings of gem-dichloroolefins.
The Journal of organic chemistry 2007;72(14):5152-60.
2007: Hulcoop David G; Lautens Mark
Palladium-catalyzed annulation of aryl heterocycles with strained alkenes.
Organic letters 2007;9(9):1761-4.
2007: Wang Letian; Maddess Matthew L; Lautens Mark
Convenient access to functionalized vinylcyclopentenols from alkynyloxiranes.
The Journal of organic chemistry 2007;72(5):1822-5.
2007: Scott Mark E; Bethuel Yann; Lautens Mark
A highly efficient and selective route to isomeric cyclic diazadienes.
Journal of the American Chemical Society 2007;129(6):1482-3.
2007: Alberico Dino; Rudolph Alena; Lautens Mark
Synthesis of tricyclic heterocycles via a tandem aryl alkylation/heck coupling sequence.
The Journal of organic chemistry 2007;72(3):775-81.
2007: Fang Yuan-Qing; Karisch Robert; Lautens Mark
Efficient syntheses of KDR kinase inhibitors using a Pd-catalyzed tandem C-N/Suzuki coupling as the key step.
The Journal of organic chemistry 2007;72(4):1341-6.
2007: Taillier Catherine; Lautens Mark
Enantioselective catalytic ring expansion of methylenecyclopropane carboxamides promoted by a chiral magnesium Lewis acid.
Organic letters 2007;9(4):591-3.
2007: Alberico Dino; Scott Mark E; Lautens Mark
Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.
Chemical reviews 2007;107(1):174-238.
2007: Rudolph Alena; Rackelmann Nils; Lautens Mark
Stereochemical and mechanistic investigations of a palladium-catalyzed annulation of secondary alkyl iodides.
Angewandte Chemie (International ed. in English) 2007;46(9):1485-8.
2007: McManus Helen A; Fleming Matthew J; Lautens Mark
Enantioselective total synthesis of (+)-homochelidonine by a PdII-catalyzed asymmetric ring-opening reaction of a meso-azabicyclic alkene with an aryl boronic acid.
Angewandte Chemie (International ed. in English) 2007;46(3):433-6.
2006: Scott Mark E; Schwarz Christina A; Lautens Mark
Synthesis of beta,gamma-unsaturated lactams via a magnesium iodide promoted ring expansion of secondary methylenecyclopropyl amides.
Organic letters 2006;8(24):5521-4.
2006: Mariampillai Brian; Alberico Dino; Bidau Valérie; Lautens Mark
Synthesis of polycyclic benzonitriles via a one-pot aryl alkylation/cyanation reaction.
Journal of the American Chemical Society 2006;128(45):14436-7.
2006: Martins Andrew; Alberico Dino; Lautens Mark
Synthesis of polycyclic heterocycles via a one-pot ortho alkylation/direct heteroarylation sequence.
Organic letters 2006;8(21):4827-9.
2006: Menard Frederic; Chapman Timothy M; Dockendorff Chris; Lautens Mark
Rhodium-catalyzed asymmetric allylic substitution with boronic acid nucleophiles.
Organic letters 2006;8(20):4569-72.
2006: Fayol Aude; Fang Yuan-Qing; Lautens Mark
Synthesis of 2-vinylic indoles and derivatives via a Pd-catalyzed tandem coupling reaction.
Organic letters 2006;8(19):4203-6.
2006: Mitsudo Koichi; Thansandote Praew; Wilhelm Thorsten; Mariampillai Brian; Lautens Mark
Selectively substituted thiophenes and indoles by a tandem palladium-catalyzed multicomponent reaction.
Organic letters 2006;8(18):3939-42.
2006: Jafarpour Farnaz; Lautens Mark
Direct, one-step synthesis of condensed heterocycles: a palladium-catalyzed coupling approach.
Organic letters 2006;8(16):3601-4.
2006: Brunner Bernhard; Stogaitis Nicole; Lautens Mark
Synthesis of 1,2-dihydropyridines using vinyloxiranes as masked dienolates in imino-aldol reactions.
Organic letters 2006;8(16):3473-6.
2006: McCubbin J Adam; Maddess Matthew L; Lautens Mark
Total synthesis of cryptophycin analogues via a scaffold approach.
Organic letters 2006;8(14):2993-6.
2006: Martins Andrew; Marquardt Udo; Kasravi Neema; Alberico Dino; Lautens Mark
Synthesis of substituted benzoxacycles via a domino ortho-alkylation/Heck coupling sequence.
The Journal of organic chemistry 2006;71(13):4937-42.
2006: Cho Yong-hwan; Zunic Valentin; Senboku Hisanori; Olsen Madeline; Lautens Mark
Rhodium-catalyzed ring-opening reactions of N-boc-azabenzonorbornadienes with amine nucleophiles.
Journal of the American Chemical Society 2006;128(21):6837-46.
2006: Blaszykowski Christophe; Aktoudianakis Evangelos; Bressy Cyril; Alberico Dino; Lautens Mark
Preparation of annulated nitrogen-containing heterocycles via a one-pot palladium-catalyzed alkylation/direct arylation sequence.
Organic letters 2006;8(10):2043-5.
2006: Tseng Nai-Wen; Mancuso John; Lautens Mark
Rhodium-catalyzed tandem vinylcyclopropanation of strained alkenes.
Journal of the American Chemical Society 2006;128(16):5338-9.
2006: Chau Anh; Paquin Jean-François; Lautens Mark
Diastereoselective palladium-catalyzed formate reduction of allylic carbonates en route to polypropionate systems.
The Journal of organic chemistry 2006;71(5):1924-33.
2006: Yuen Josephine; Fang Yuan-Qing; Lautens Mark
CuI-Catalyzed tandem intramolecular amidation using gem-dibromovinyl systems.
Organic letters 2006;8(4):653-6.
2005: Dockendorff Chris; Sahli Stefan; Olsen Madeline; Milhau Ludovic; Lautens Mark
Synthesis of dihydronaphthalenes via aryne Diels-Alder reactions: scope and diastereoselectivity.
Journal of the American Chemical Society 2005;127(43):15028-9.
2005: Mariampillai Brian; Herse Christelle; Lautens Mark
Intermolecular Heck-type coupling of aryl iodides and allylic acetates.
Organic letters 2005;7(21):4745-7.
2005: Bressy Cyril; Alberico Dino; Lautens Mark
A route to annulated indoles via a palladium-catalyzed tandem alkylation/direct arylation reaction.
Journal of the American Chemical Society 2005;127(38):13148-9.
2005: Wilhelm Thorsten; Lautens Mark
Palladium-catalyzed alkylation-hydride reduction sequence: synthesis of meta-substituted arenes.
Organic letters 2005;7(18):4053-6.
2005: Maddess Matthew L; Lautens Mark
Preparation of homoallylic homopropargylic alcohols from 2-vinyloxiranes.
Organic letters 2005;7(16):3557-60.
2005: Fang Yuan-Qing; Lautens Mark
Pd-catalyzed tandem C-N/C-C coupling of gem-dihalovinyl systems: a modular synthesis of 2-substituted indoles.
Organic letters 2005;7(16):3549-52.
2005: Scott Mark E; Lautens Mark
Total synthesis of (-)-(alpha)-kainic acid via a diastereoselective methylenecyclopropane ring expansion.
Organic letters 2005;7(14):3045-7.
2005: Lautens Mark; Tayama Eiji; Herse Christelle
Palladium-catalyzed intramolecular coupling between aryl iodides and allyl moieties via thermal and microwave-assisted conditions.
Journal of the American Chemical Society 2005;127(1):72-3.
2004: Scott Mark E; Han Wooseok; Lautens Mark
A highly diastereoselective MgI2-mediated ring expansion of methylenecyclopropanes.
Organic letters 2004;6(19):3309-12.
2004: Lautens Mark; Marquardt Tzvetelina
Rhodium-catalyzed tandem cyclization: formation of 1H-indenes and 1-alkylideneindans from arylboronate esters in aqueous media.
The Journal of organic chemistry 2004;69(14):4607-14.
2004: Lautens Mark; Maddess Matthew L
Chemoselective cross metathesis of bishomoallylic alcohols: rapid access to fragment a of the cryptophycins.
Organic letters 2004;6(12):1883-6.
2004: Lautens Mark; Mancuso John
Addition of bifunctional organoboron reagents to strained alkenes. Carbon-carbon bond formation with Rh(I) catalysis in aqueous media.
The Journal of organic chemistry 2004;69(10):3478-87.
2004: Lautens Mark; Fagnou Keith
Rhodium-catalyzed asymmetric ring opening reactions of oxabicyclic alkenes: catalyst and substrate studies leading to a mechanistic working model.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(15):5455-60.
2004: Leong Paul; Lautens Mark
Rhodium-catalyzed asymmetric ring opening of oxabicyclic alkenes with sulfur nucleophiles.
The Journal of organic chemistry 2004;69(6):2194-6.
2004: Lautens Mark; Hiebert Sheldon
Scope of palladium-catalyzed alkylative ring opening.
Journal of the American Chemical Society 2004;126(5):1437-47.
2004: Lautens Mark; Tayama Eiji; Nguyen Duy
Direct vinylogous Mannich-type reactions via ring opening and rearrangement of vinyloxiranes.
Organic letters 2004;6(3):345-7.
2003: Pache Sandrine; Lautens Mark
Palladium-catalyzed sequential alkylation-alkenylation reactions: new three-component coupling leading to oxacycles.
Organic letters 2003;5(25):4827-30.
2003: Lautens Mark; Fagnou Keith; Yang Dingqiao
Rhodium-catalyzed asymmetric ring opening reactions of oxabicyclic alkenes: application of halide effects in the development of a general process.
Journal of the American Chemical Society 2003;125(48):14884-92.
2003: Lautens Mark; Dockendorff Chris
Palladium(II) catalyst systems for the addition of boronic acids to bicyclic alkenes: new scope and reactivity.
Organic letters 2003;5(20):3695-8.
2003: Lautens Mark; Fang Yuan-Qing
Synthesis of novel tetracycles via an intramolecular Heck reaction with anti-hydride elimination.
Organic letters 2003;5(20):3679-82.
2003: Lautens Mark; Paquin Jean-François
Diastereoselective palladium-catalyzed formate reduction of allylic carbonates as a new entry into propionate units.
Organic letters 2003;5(19):3391-4.
2003: Mancuso John; Lautens Mark
Mild procedure for the catalytic bis(stannylation) of alkynes with hexaalkylditins.
Organic letters 2003;5(10):1653-5.
2003: Lautens Mark; Han Wooseok; Liu Jack Hung-Chang
MgI(2)-mediated ring expansions of secondary methylenecyclopropyl amides.
Journal of the American Chemical Society 2003;125(14):4028-9.
2003: Lautens Mark; Yoshida Masahiro
Rhodium-catalyzed addition of arylboronic acids to alkynyl aza-heteroaromatic compounds in water.
The Journal of organic chemistry 2003;68(3):762-9.
2003: Lautens Mark; Fagnou Keith; Hiebert Sheldon
Transition metal-catalyzed enantioselective ring-opening reactions of oxabicyclic alkenes.
Accounts of chemical research 2003;36(1):48-58.
2003: Fagnou Keith; Lautens Mark
Rhodium-catalyzed carbon-carbon bond forming reactions of organometallic compounds.
Chemical reviews 2003;103(1):169-96.
2002: Lautens Mark; Schmid Gavin A; Chau Anh
Remote electronic effects in the rhodium-catalyzed nucleophilic ring opening of oxabenzonorbornadienes.
The Journal of organic chemistry 2002;67(23):8043-53.
2002: Lautens Mark; Fagnou Keith; Zunic Valentin
An expedient enantioselective route to diaminotetralins: application in the preparation of analgesic compounds.
Organic letters 2002;4(20):3465-8.
2002: Lautens Mark; Mancuso John
Diastereoselective formation of indanes from arylboronate esters catalyzed by rhodium(I) in aqueous media.
Organic letters 2002;4(12):2105-8.
2002: Lautens Mark; Han Wooseok
Divergent selectivity in MgI(2)-mediated ring expansions of methylenecyclopropyl amides and imides.
Journal of the American Chemical Society 2002;124(22):6312-6.
2002: Lautens Mark; Paquin Jean-François; Piguel Sandrine
Palladium-catalyzed sequential alkylation-alkenylation reactions. Application to the synthesis of 2-substituted-4-benzoxepines and 2,5-disubstituted-4-benzoxepines.
The Journal of organic chemistry 2002;67(11):3972-4.
2002: Lautens Mark; Colucci John T; Hiebert Sheldon; Smith Nicholas D; Bouchain Giliane
Total synthesis of ionomycin using ring-opening strategies.
Organic letters 2002;4(11):1879-82.
2002: Lautens Mark; Dockendorff Chris; Fagnou Keith; Malicki Adrianna
Rhodium-catalyzed asymmetric ring opening of oxabicyclic alkenes with organoboronic acids.
Organic letters 2002;4(8):1311-4.
2002: Fagnou Keith; Lautens Mark
Halide effects in transition metal catalysis.
Angewandte Chemie (International ed. in English) 2002;41(1):27-47.
2002: Lautens Mark; Yoshida Masahiro
Regioselective rhodium-catalyzed addition of arylboronic acids to alkynes with a pyridine-substituted water-soluble ligand.
Organic letters 2002;4(1):123-5.
2002: Lautens Mark; Maddess Matthew L; Sauer Effiette L O; Ouellet Stéphane G
Enantioselective allylation of beta,gamma-unsaturated aldehydes generated via Lewis acid induced rearrangement of 2-vinyloxiranes.
Organic letters 2002;4(1):83-6.
2001: Lautens M; Paquin J F; Piguel S; Dahlmann M
Palladium-catalyzed sequential alkylation-alkenylation reactions and their application to the synthesis of fused aromatic rings.
The Journal of organic chemistry 2001;66(24):8127-34.
2001: Lautens M; Fagnou K
Effects of halide ligands and protic additives on enantioselectivity and reactivity in rhodium-catalyzed asymmetric ring-opening reactions.
Journal of the American Chemical Society 2001;123(29):7170-1.
2001: Lautens M; Roy A; Fukuoka K; Fagnou K; Martín-Matute B
Rhodium-catalyzed coupling reactions of arylboronic acids to olefins in aqueous media.
Journal of the American Chemical Society 2001;123(22):5358-9.

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