FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Edward LaVallie

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Chemicals & Drugs

Living Beings

Procedures

Anatomy

Chondrocytes

Disorders

Osteoarthritis

Co-author Network

Publications

TOP 3
Heather H Shih; Chao Tu; Leeying Wu; Mostafa Ait-Zahra; Maya Arai; Bénédicte Autin; Joel Bard; Steven Braithwaite; Wei Cao; Christopher Corcoran; Orla Cunningham; Jo Ann Dumin; Brian J Fennell; Davinder Gill; Anne Klein; Eugenia Kouranova; Matthew Lambert; Edward R LaVallie; Sri Laxmanan; Anthony J Milici; Lidia Mosyak; Deirdre Ní Shúilleabháin; Janet E Paulsen; Renee Ramsey; William J J Finlay
An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.
Ilia Goltsman; Xinkang Wang; Edward R LaVallie; Elizabeth A Diblasio-Smith; Elena Ovcharenko; Aaron Hoffman; Zaid Abassi; Giora Z Feuerstein; Joseph Winaver
Effects of chronic rosiglitazone treatment on renal handling of salt and water in rats with volume-overload congestive heart failure.
Eirini Christaki; Steven M Opal; James C Keith; Nubar Kessimian; John E Palardy; Nicolas A Parejo; Xiang Yang Tan; Nicole Piche-Nicholas; Lioudmila Tchistiakova; George P Vlasuk; Kathleen M Shields; Jeffrey L Feldman; Edward R LaVallie; Maya Arai; William Mounts; Debra D Pittman
A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Edward LaVallie (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Heather H Shih; Chao Tu; Leeying Wu; Mostafa Ait-Zahra; Maya Arai; Bénédicte Autin; Joel Bard; Steven Braithwaite; Wei Cao; Christopher Corcoran; Orla Cunningham; Jo Ann Dumin; Brian J Fennell; Davinder Gill; Anne Klein; Eugenia Kouranova; Matthew Lambert; Edward R LaVallie; Sri Laxmanan; Anthony J Milici; Lidia Mosyak; Deirdre Ní Shúilleabháin; Janet E Paulsen; Renee Ramsey; William J J Finlay
An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.
The Journal of biological chemistry 2012;287(53):44425-34.
2011: Ilia Goltsman; Xinkang Wang; Edward R LaVallie; Elizabeth A Diblasio-Smith; Elena Ovcharenko; Aaron Hoffman; Zaid Abassi; Giora Z Feuerstein; Joseph Winaver
Effects of chronic rosiglitazone treatment on renal handling of salt and water in rats with volume-overload congestive heart failure.
Circulation. Heart failure 2011;4(3):345-54.
2011: Eirini Christaki; Steven M Opal; James C Keith; Nubar Kessimian; John E Palardy; Nicolas A Parejo; Xiang Yang Tan; Nicole Piche-Nicholas; Lioudmila Tchistiakova; George P Vlasuk; Kathleen M Shields; Jeffrey L Feldman; Edward R LaVallie; Maya Arai; William Mounts; Debra D Pittman
A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia.
Shock (Augusta, Ga.) 2011;35(5):492-8.
2010: Xinkang Wang; Xiaorong Liu; Yutian Zhan; Edward R LaVallie; Liz Diblasio-Smith; Lisa Collins-Racie; William M Mounts; J Lynn Rutkowski; Xin Xu; Ilia Goltsman; Zaid Abassi; Joseph Winaver; Giora Z Feuerstein
Pharmacogenomic, physiological, and biochemical investigations on safety and efficacy biomarkers associated with the peroxisome proliferator-activated receptor-gamma activator rosiglitazone in rodents: a translational medicine investigation.
The Journal of pharmacology and experimental therapeutics 2010;334(3):820-9.
2010: Ning Li; Moisés A Rivéra-Bermúdez; Mei Zhang; Julio Tejada; Sonya S Glasson; Lisa A Collins-Racie; Edward R LaVallie; Yihe Wang; Ken C N Chang; Sunil Nagpal; Elisabeth A Morris; Carl R Flannery; Zhiyong Yang
LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3734-9.
2010: Maya Arai; Sadhana Jain; Amy A Weaver; Andrew A Hill; Yongjing Guo; Andrea G Bree; Michael Smith, Jr.; Scott W Allen; Edward R LaVallie; Deborah Young; Laird Bloom; Karissa Adkins; Margot O'Toole
Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood.
Journal of translational medicine 2010;8():51.
2010: Yongjing Guo; Andrew A Hill; Renee C Ramsey; Frederick W Immermann; Christopher Corcoran; Deborah Young; Edward R LaVallie; Mark Ryan; Theresa Bechard; Richard Pfeifer; Garvin Warner; Marcia Bologna; Laird Bloom; Margot O'Toole
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.
Journal of translational medicine 2010;8():50.
2009: Elaine Quinet; Michael D Basso; Anita R Halpern; David W Yates; Robert J Steffan; Valerie Clerin; Christine Resmini; James C Keith; Thomas J Berrodin; Irene Feingold; Wenyan Zhong; Helen B Hartman; Mark J Evans; Stephen J Gardell; Elizabeth DiBlasio-Smith; William M Mounts; Edward R LaVallie; Jay Wrobel; Ponnal Nambi; George P Vlasuk
LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse.
Journal of lipid research 2009;50(12):2358-70.
2009: Angela Chamberland; Eunice Wang; Aled R Jones; Lisa A Collins-Racie; Edward R LaVallie; Ying Huang; Lin Liu; Elisabeth A Morris; Carl R Flannery; Zhiyong Yang
Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo.
The Journal of biological chemistry 2009;284(40):27352-9.
2009: Kishore M Lakshman; Shalender Bhasin; Christopher Corcoran; Lisa A Collins-Racie; Lioudmila Tchistiakova; S Bradley Forlow; Katie St Ledger; Michael E Burczynski; Andrew J Dorner; Edward R LaVallie
Measurement of myostatin concentrations in human serum: Circulating concentrations in young and older men and effects of testosterone administration.
Molecular and cellular endocrinology 2009;302(1):26-32.
2008: Edward R LaVallie; Andrew J Dorner; Michael Burczynski
Use of ex vivo systems for biomarker discovery.
Current opinion in pharmacology 2008;8(5):647-53.
2008: Kathryn R Wagner; James L Fleckenstein; Anthony A Amato; Richard J Barohn; Katharine Bushby; Diana Escolar; Kevin M Flanigan; Alan Pestronk; Rabi Tawil; Gil I Wolfe; Michelle Eagle; Julaine M Florence; Wendy M King; Shree Pandya; Volker Straub; Paul Juneau; Kathleen Meyers; Cristina Csimma; Tracey Araujo; Robert Allen; Stephanie A Parsons; John M Wozney; Edward R LaVallie; Jerry R Mendell
A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy.
Annals of neurology 2008;63(5):561-71.
2008: Elizabeth A DiBlasio-Smith; Maya Arai; Elaine Quinet; Mark J Evans; Tad Kornaga; Michael D Basso; Liang Chen; Irene Feingold; Anita R Halpern; Qiang-Yuan Liu; Ponnal Nambi; Dawn Savio; Shuguang Wang; William M Mounts; Jennifer A Isler; Anna M Slager; Michael Burczynski; Andrew J Dorner; Edward R LaVallie
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
Journal of translational medicine 2008;6():59.
2008: Lidia Mosyak; Katy E Georgiadis; Tania Shane; Kristine Svenson; Tracy Hebert; Thomas McDonagh; Stewart Mackie; Stephane Olland; Laura Lin; Xiaotian Zhong; Ron Kriz; Erica L Reifenberg; Lisa A Collins-Racie; Chris Corcoran; Bethany Freeman; Richard Zollner; Tod Marvell; Matthew Vera; Phaik-Eng Sum; Edward R LaVallie; Mark L Stahl; William Somers
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein science : a publication of the Protein Society 2008;17(1):16-21.
2007: Priya S Chockalingam; Usha Varadarajan; Richard Sheldon; Eric Fortier; Edward R LaVallie; Elisabeth A Morris; Paul J Yaworsky; Manas Majumdar
Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes.
Arthritis and rheumatism 2007;56(12):4074-83.
2006: Edward R LaVallie; Priya S Chockalingam; Lisa A Collins-Racie; Bethany A Freeman; Cristin C Keohan; Michael Leitges; Andrew J Dorner; Elisabeth A Morris; Manas Majumdar; Maya Arai
Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.
The Journal of biological chemistry 2006;281(34):24124-37.
2006: Kristie Bridges; Rajiv Chopra; Laura Lin; Kristine Svenson; Amy Tam; Guixian Jin; Rebecca Cowling; Frank Lovering; Tatos N Akopian; Elizabeth DiBlasio-Smith; Bethany Annis-Freeman; Tod H Marvell; Edward R LaVallie; Richard Zollner; Jonathan Bard; William S Somers; Mark L Stahl; Ron Kriz
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis.
Peptides 2006;27(7):1877-85.
2006: Weilan Zeng; Chris Corcoran; Lisa A Collins-Racie; Edward R LaVallie; Elisabeth A Morris; Carl R Flannery
Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.
Biochimica et biophysica acta 2006;1760(3):517-24.
2004: Patricia Jensen; Susan M Magdaleno; Karen M Lehman; Dennis S Rice; Edward R LaVallie; Lisa A Collins-Racie; John McCoy; Tom Curran
A neurogenomics approach to gene expression analysis in the developing brain.
Brain research. Molecular brain research 2004;132(2):116-27.
2004: Elizabeth Bromley; Dunja Knapp; Fiona Wardle; Benjamin I Sun; Lisa A Collins-Racie; Edward R LaVallie; Jim Smith; Hazel Sive
Identification and characterisation of the posteriorly-expressed Xenopus neurotrophin receptor homolog genes fullback and fullback-like.
Gene expression patterns : GEP 2004;5(1):135-40.
2004: Maya Arai; Dina Anderson; Yahya Kurdi; Bethany Annis-Freeman; Kathleen Shields; Lisa A Collins-Racie; Chris Corcoran; Elizabeth DiBlasio-Smith; Debra D Pittman; Andrew J Dorner; Elisabeth Morris; Edward R LaVallie
Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(8):599-613.
2004: Lisa A Collins-Racie; Carl R Flannery; Weilan Zeng; Chris Corcoran; Bethany Annis-Freeman; Michael J Agostino; Maya Arai; Elizabeth DiBlasio-Smith; Andrew J Dorner; Katy E Georgiadis; Macy Jin; Xiang-Yang Tan; Elisabeth A Morris; Edward R LaVallie
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage.
Matrix biology : journal of the International Society for Matrix Biology 2004;23(4):219-30.
2003: Zhijian Lu; Edward R LaVallie; John McCoy
Using bio-panning of FLITRX peptide libraries displayed on E. coli cell surface to study protein-protein interactions.
Methods in molecular biology (Clifton, N.J.) 2003;205():267-80.
2003: Edward R LaVallie; Elizabeth DiBlasio-Smith; Lisa A Collins-Racie; Zhijian Lu; John McCoy
Thioredoxin and related proteins as multifunctional fusion tags for soluble expression in E. coli.
Methods in molecular biology (Clifton, N.J.) 2003;205():119-40.
2002: Carl R Flannery; Weilan Zeng; Chris Corcoran; Lisa A Collins-Racie; Priya S Chockalingam; Tracy Hebert; Stewart A Mackie; Thomas McDonagh; Tara K Crawford; Kathy N Tomkinson; Edward R LaVallie; Elisabeth A Morris
Autocatalytic cleavage of ADAMTS-4 (Aggrecanase-1) reveals multiple glycosaminoglycan-binding sites.
The Journal of biological chemistry 2002;277(45):42775-80.
2002: Julia A Horsfield; Anassuya Ramachandran; Katja Reuter; Edward R LaVallie; Lisa A Collins-Racie; Kathryn E Crosier; Philip S Crosier
Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development.
Mechanisms of development 2002;115(1-2):15-26.
2002: Jennifer Westling; Amanda J Fosang; Karena Last; Vivian P Thompson; Kathy N Tomkinson; Tracy Hebert; Thomas McDonagh; Lisa A Collins-Racie; Edward R LaVallie; Elisabeth A Morris; John D Sandy
ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain.
The Journal of biological chemistry 2002;277(18):16059-66.
2001: Philip S Crosier; A Bardsley; Julia A Horsfield; A K Krassowska; Edward R LaVallie; Lisa A Collins-Racie; John H Postlethwait; Y L Yan; John McCoy; Kathryn E Crosier
In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;222(4):637-44.
2001: Edward R LaVallie
Production of recombinant proteins in Escherichia coli.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2001;Chapter 5():Unit5.1.
2001: J McCoy; Edward R LaVallie
Expression and purification of thioredoxin fusion proteins.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 16():Unit16.8.
2001: Edward R LaVallie; John McCoy; D B Smith; Paul Riggs
Enzymatic and chemical cleavage of fusion proteins.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 16():Unit16.4B.
2001: DM Smith; Lisa A Collins-Racie; V A Marigo; Drucilla J Roberts; N M Davis; C Hartmann; Ronen Schweitzer; Edward R LaVallie; L Gamer; J McCoy; Clifford J Tabin
Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo.
Mechanisms of development 2001;102(1-2):223-6.
2000: L Bradley; B Sun; Lisa A Collins-Racie; Edward R LaVallie; J McCoy; Hazel Sive
Different activities of the frizzled-related proteins frzb2 and sizzled2 during Xenopus anteroposterior patterning.
Developmental biology 2000;227(1):118-32.
2000: Sha Mi; Xinhua Lee; X Li; G M Veldman; HF Finnerty; L Racie; Edward R LaVallie; X Y Tang; P Edouard; S Howes; James Carl Keith; John McCoy
Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis.
Nature 2000;403(6771):785-9.
2000: Edward R LaVallie; Zhijian Lu; Elizabeth DiBlasio-Smith; Lisa A Collins-Racie; John McCoy
Thioredoxin as a fusion partner for production of soluble recombinant proteins in Escherichia coli.
Methods in enzymology 2000;326():322-40.
1999: Benjamin I Sun; S M Bush; Lisa A Collins-Racie; Edward R LaVallie; Elizabeth DiBlasio-Smith; N M Wolfman; John McCoy; Hazel Sive
derrière: a TGF-beta family member required for posterior development in Xenopus.
Development (Cambridge, England) 1999;126(7):1467-82.
1998: P A Smith; BC Tripp; Elizabeth DiBlasio-Smith; Zhijian Lu; Edward R LaVallie; John McCoy
A plasmid expression system for quantitative in vivo biotinylation of thioredoxin fusion proteins in Escherichia coli.
Nucleic acids research 1998;26(6):1414-20.
1997: Kenneth A Jacobs; Lisa A Collins-Racie; M Colbert; M Duckett; M Golden-Fleet; Kerry Kelleher; Ron Kriz; Edward R LaVallie; D Merberg; Vikki Spaulding; J Stover; M J Williamson; John McCoy
A genetic selection for isolating cDNAs encoding secreted proteins.
Gene 1997;198(1-2):289-96.
1996: Zhijian Lu; Elizabeth DiBlasio-Smith; K L Grant; Nicholas Warne; Edward R LaVallie; Lisa A Collins-Racie; M T Follettie; M J Williamson; John McCoy
Histidine patch thioredoxins. Mutant forms of thioredoxin with metal chelating affinity that provide for convenient purifications of thioredoxin fusion proteins.
The Journal of biological chemistry 1996;271(9):5059-65.
1996: L A Vozza; L Wittwer; DR Higgins; T J Purcell; M Bergseid; Lisa A Collins-Racie; Edward R LaVallie; JP Hoeffler
Production of a recombinant bovine enterokinase catalytic subunit in the methylotrophic yeast Pichia pastoris.
Bio/technology (Nature Publishing Company) 1996;14(1):77-81.
1995: Edward R LaVallie; John McCoy
Gene fusion expression systems in Escherichia coli.
Current opinion in biotechnology 1995;6(5):501-6.
1995: Lisa A Collins-Racie; J M McColgan; K L Grant; Elizabeth DiBlasio-Smith; John McCoy; Edward R LaVallie
Production of recombinant bovine enterokinase catalytic subunit in Escherichia coli using the novel secretory fusion partner DsbA.
Bio/technology (Nature Publishing Company) 1995;13(9):982-7.
1995: Zhijian Lu; K S Murray; V Van Cleave; Edward R LaVallie; M L Stahl; John McCoy
Expression of thioredoxin random peptide libraries on the Escherichia coli cell surface as functional fusions to flagellin: a system designed for exploring protein-protein interactions.
Bio/technology (Nature Publishing Company) 1995;13(4):366-72.
1993: Edward R LaVallie; Alnawaz Rehemtulla; L A Racie; E A DiBlasio; C Ferenz; K L Grant; A Light; John McCoy
Cloning and functional expression of a cDNA encoding the catalytic subunit of bovine enterokinase.
The Journal of biological chemistry 1993;268(31):23311-7.
1993: Edward R LaVallie; E A DiBlasio; S Kovacic; K L Grant; P F Schendel; John McCoy
A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm.
Bio/technology (Nature Publishing Company) 1993;11(2):187-93.
1989: Edward R LaVallie; M L Stahl
Cloning of the flagellin gene from Bacillus subtilis and complementation studies of an in vitro-derived deletion mutation.
Journal of bacteriology 1989;171(6):3085-94.