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Bin Bao

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Zhiwei Wang; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Bin Bao; Murray Korc; Yiwei Li; Fazlul H Sarkar
Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype.
Ashhar S Ali; Shadan Ali; Bin Bao; Philip A Philip; Aamir Ahmad; Fazlul H Sarkar
The role of cancer stem cells and miRNAs in defining the complexities of brain metastasis.
Bin Bao; Ginny Bao; Dejuan Kong; Yiwei Li; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Fazlul H Sarkar
Targeting CSC-related miRNAs for cancer therapy by natural agents.

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All Publications

2013: Zhiwei Wang; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Bin Bao; Murray Korc; Yiwei Li; Fazlul H Sarkar
Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype.
Journal of cellular physiology 2013;228(3):556-62.
2013: Ashhar S Ali; Shadan Ali; Bin Bao; Philip A Philip; Aamir Ahmad; Fazlul H Sarkar
The role of cancer stem cells and miRNAs in defining the complexities of brain metastasis.
Journal of cellular physiology 2013;228(1):36-42.
2012: Bin Bao; Ginny Bao; Dejuan Kong; Yiwei Li; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Fazlul H Sarkar
Targeting CSC-related miRNAs for cancer therapy by natural agents.
Current drug targets 2012;13(14):1858-68.
2012: Aamir Ahmad; Shadan Ali; Sanjeev Banerjee; Bin Bao; Bernhard Biersack; Dejuan Kong; Yiwei Li; Subhash B Padhye; Sarah H Sarkar; Rainer Schobert; Sebastian Seibt; Amro Aboukameel; Fazlul H Sarkar
Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling.
Carcinogenesis 2012;33(12):2450-6.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Asfar S Azmi
The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.
Biochimica et biophysica acta 2012;1826(2):272-96.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Asfar S Azmi
Targeting CSCs within the tumor microenvironment for cancer therapy: a potential role of mesenchymal stem cells.
Expert opinion on therapeutic targets 2012;16(10):1041-54.
2012: Aamir Ahmad; Shadan Ali; Sanjeev Banerjee; Bin Bao; Bassam Bitar; Dejuan Kong; Yiwei Li; Subhash Padhye; Sarah H Sarkar; Seema Sethi; Amro Aboukameel; Asfar S Azmi
Garcinol regulates EMT and Wnt signaling pathways in vitro and in vivo, leading to anticancer activity against breast cancer cells.
Molecular cancer therapeutics 2012;11(10):2193-201.
2012: Shadan Ali; Sanjeev Banerjee; Bin Bao; Murray Korc; Farah Logna; Philip A Philip; Asfar S Azmi
Inactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer.
Journal of cellular physiology 2012;227(10):3373-80.
2012: Yiwei Li; Aamir Ahmad; Bin Bao; Gregory Dyson; Dejuan Kong; Asfar S Azmi
Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion.
Epigenetics : official journal of the DNA Methylation Society 2012;7(8):940-9.
2012: Shadan Ali; Bin Bao; Subhash Padhye; Philip A Philip; Amro Aboukameel; Aamir Ahmad; Asfar S Azmi
Increased Ras GTPase activity is regulated by miRNAs that can be attenuated by CDF treatment in pancreatic cancer cells.
Cancer letters 2012;319(2):173-81.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Lawrence George Lum; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Archana Thakur; Asfar S Azmi
The immunological contribution of NF-κB within the tumor microenvironment: a potential protective role of zinc as an anti-tumor agent.
Biochimica et biophysica acta 2012;1825(2):160-72.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Sanila H Sarkar; Shivam Thakur; Zhiwei Wang; Asfar S Azmi
Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells.
Cancer prevention research (Philadelphia, Pa.) 2012;5(3):355-64.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Subhash B Padhye; Amro Aboukameel; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Seema Sethi; Fazlul H Sarkar
Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment.
PloS one 2012;7(12):e50165.
2012: Dejuan Kong; Yiwei Li; Aamir Ahmad; Sanjeev Banerjee; Bin Bao; Asfar S Azmi
Histone deacetylase inhibitors induce epithelial-to-mesenchymal transition in prostate cancer cells.
PloS one 2012;7(9):e45045.
2012: Bin Bao; Dejuan Kong; Yiwei Li; Subhash Padhye; Aamir Ahmad; Shadan Ali; Asfar S Azmi; Sanjeev Banerjee; Fazlul H Sarkar
Hypoxia induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF.
PloS one 2012;7(8):e43726.
2012: Yiwei Li; Aamir Ahmad; Bin Bao; Dejuan Kong; Asfar S Azmi
Targeting bone remodeling by isoflavone and 3,3'-diindolylmethane in the context of prostate cancer bone metastasis.
PloS one 2012;7(3):e33011.
2012: Yiwei Li; Ma'in Y Maitah; Aamir Ahmad; Bin Bao; Dejuan Kong; Asfar S Azmi
Targeting the Hedgehog signaling pathway for cancer therapy.
Expert opinion on therapeutic targets 2012;16(1):49-66.
2011: Asfar S Azmi; Bin Bao; Frances W J Beck; Ramzi M Mohammad; Fazlul H Sarkar
Aberrant epigenetic grooming of miRNAs in pancreatic cancer: a systems biology perspective.
Epigenomics 2011;3(6):747-59.
2011: Yiwei Li; Aamir Ahmad; Bin Bao; Dejuan Kong; Asfar S Azmi
Induction of cancer cell death by isoflavone: the role of multiple signaling pathways.
Nutrients 2011;3(10):877-96.
2011: Yiwei Li; Subhash Padhye; Aamir Ahmad; Bin Bao; Dejuan Kong; Zhiwei Wang; Asfar S Azmi
Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells.
Cancer prevention research (Philadelphia, Pa.) 2011;4(9):1495-506.
2011: Bin Bao; Dejuan Kong; Yiwei Li; Lucio Miele; Aamir Ahmad; Shadan Ali; ASFAR AZMI; Sanjeev Banerjee; Zhiwei Wang; Asfar S Azmi
Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells.
Journal of cellular biochemistry 2011;112(9):2296-306.
2011: Bin Bao; Zhiwei Wang; Shadan Ali; Dejuan Kong; Yiwei Li; Aamir Ahmad; Sanjeev Banerjee; ASFAR AZMI; Lucio Miele; Asfar S Azmi
Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells.
Cancer letters 2011;307(1):26-36.
2011: Sanjeev Banerjee; Bin Bao; Gilda G Hillman; Dejuan Kong; Zhiwei Wang; Asfar S Azmi
Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): from bench to clinic.
Mutation research 2011;728(1-2):47-66.
2011: Ananda S Prasad; Bin Bao; Frances W J Beck; Asfar S Azmi
Zinc-suppressed inflammatory cytokines by induction of A20-mediated inhibition of nuclear factor-κB.
Nutrition (Burbank, Los Angeles County, Calif.) 2011;27(7-8):816-23.
2011: Asfar S Azmi; Sanjeev Banerjee; Bin Bao; Frances W J Beck; Minsig Choi; Main Maitah; Philip A Philip; Fazlul H Sarkar; Tony F Shields; Zhiwei Wang; Shadan Ali; Ramzi M Mohammad
Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors.
Oncotarget 2011;2(5):378-92.
2011: Bin Bao; Ananda S Prasad; Frances W J Beck; Ginny W Bao; Tapinder Singh; Shadan Ali; Asfar S Azmi
Intracellular free zinc up-regulates IFN-γ and T-bet essential for Th1 differentiation in Con-A stimulated HUT-78 cells.
Biochemical and biophysical research communications 2011;407(4):703-7.
2011: Bin Bao; Zhiwei Wang; Yiwei Li; Dejuan Kong; Shadan Ali; Sanjeev Banerjee; Aamir Ahmad; Asfar S Azmi
The complexities of obesity and diabetes with the development and progression of pancreatic cancer.
Biochimica et biophysica acta 2011;1815(2):135-46.
2011: Zhiwei Wang; Aamir Ahmad; Shadan Ali; Asfar S Azmi; Sanjeev Banerjee; Bin Bao; Jiankun Gao; Jason R Gunn; Dejuan Kong; Murray Korc; Yiwei Li; Lucio Miele; Ramzi M Mohammad; Fazlul H Sarkar
Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways.
PloS one 2011;6(6):e20537.
2011: Aamir Ahmad; Zhiwei Wang; Christine Wojewoda; Raza Ali; Dejuan Kong; Ma'in Y Maitah; Sanjeev Banerjee; Bin Bao; Subhash Padhye; Asfar S Azmi
Garcinol-induced apoptosis in prostate and pancreatic cancer cells is mediated by NF- kappaB signaling.
Frontiers in bioscience (Elite edition) 2011;3():1483-92.
2011: Bin Bao; Shadan Ali; Dejuan Kong; Sanila H Sarkar; Zhiwei Wang; Sanjeev Banerjee; Amro Aboukameel; Subhash Padhye; Philip A Philip; Asfar S Azmi
Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer.
PloS one 2011;6(3):e17850.
2010: Bin Bao; Ananda S Prasad; Frances W J Beck; James T Fitzgerald; Diane Snell; Ginny W Bao; Tapinder Singh; Lavoisier J Cardozo
Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
The American journal of clinical nutrition 2010;91(6):1634-41.
2008: Bin Bao; Ananda S Prasad; Frances W J Beck; Diane Snell; Anupam Suneja; Asfar S Azmi; Nimisha Doshi; James T Fitzgerald; Paul Steven Swerdlow
Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients.
Translational research : the journal of laboratory and clinical medicine 2008;152(2):67-80.
2008: Ananda S Prasad; Frances W J Beck; Bin Bao; Diane Snell; James T Fitzgerald
Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate.
The Journal of infectious diseases 2008;197(6):795-802.
2007: Bin Bao; Ananda S Prasad; Frances W J Beck; Asfar S Azmi
Zinc up-regulates NF-kappaB activation via phosphorylation of IkappaB in HUT-78 (Th0) cells.
FEBS letters 2007;581(23):4507-11.
2007: Ananda S Prasad; Frances W J Beck; Bin Bao; James T Fitzgerald; Diane C Snell; Joel David Steinberg; Lavoisier J Cardozo
Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress.
The American journal of clinical nutrition 2007;85(3):837-44.
2006: Ananda S Prasad; Bin Bao; Frances W J Beck; Asfar S Azmi
Correction of interleukin-2 gene expression by in vitro zinc addition to mononuclear cells from zinc-deficient human subjects: a specific test for zinc deficiency in humans.
Translational research : the journal of laboratory and clinical medicine 2006;148(6):325-33.
2006: Bin Bao; Ananda S Prasad; Frances W J Beck; Anupam Suneja; Asfar S Azmi
Toxic effect of zinc on NF-kappaB, IL-2, IL-2 receptor alpha, and TNF-alpha in HUT-78 (Th(0)) cells.
Toxicology letters 2006;166(3):222-8.
2006: Frances W J Beck; Yiwei Li; Bin Bao; Ananda S Prasad; Asfar S Azmi
Evidence for reprogramming global gene expression during zinc deficiency in the HUT-78 cell line.
Nutrition (Burbank, Los Angeles County, Calif.) 2006;22(10):1045-56.
2004: Ananda S Prasad; Bin Bao; Frances W J Beck; Omer Kucuk; Asfar S Azmi
Antioxidant effect of zinc in humans.
Free radical biology & medicine 2004;37(8):1182-90.
2003: Bin Bao; Ananda S Prasad; Frances W J Beck; Michele Godmere
Zinc modulates mRNA levels of cytokines.
American journal of physiology. Endocrinology and metabolism 2003;285(5):E1095-102.
2002: Ananda S Prasad; Bin Bao; Frances W J Beck; Asfar S Azmi
Zinc enhances the expression of interleukin-2 and interleukin-2 receptors in HUT-78 cells by way of NF-kappaB activation.
The Journal of laboratory and clinical medicine 2002;140(4):272-89.
2001: Ananda S Prasad; Bin Bao; Frances W J Beck; Asfar S Azmi
Zinc activates NF-kappaB in HUT-78 cells.
The Journal of laboratory and clinical medicine 2001;138(4):250-6.
2000: Ananda S Prasad; James T Fitzgerald; Bin Bao; Frances W J Beck; Pranatharthi H Chandrasekar
Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial.
Annals of internal medicine 2000;133(4):245-52.