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Shunzhong Bao

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Procedures

Spectrometry, Mass, Electrospray Ionization

Disorders

Insulinoma

Anatomy

Physiology

Enzymologic Gene Expression Regulation

Living Beings

Mice

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Network (preview)

Co-Publications
Name
10
Ramanadham, Sasanka
10
Turk, John
6
Bohrer, Alan
4
Wohltmann, Mary
3
Hsu, Fong-Fu
3
Ma, Zhongmin
2
Zhang, Sheng
1
Semenkovich, Clay
1
Ma, Zhongmin Alex
1
Mancuso, David
1
Moley, Kelle
1
Philipson, Louis
1
Jacobson, David
1
Crankshaw, Mark
1
Gross, Richard

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Publications

TOP 3
Bao Shunzhong; Jacobson David A; Wohltmann Mary; Bohrer Alan; Jin Wu; Philipson Louis H; Turk John
Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
Lei Xiaoyong; Zhang Sheng; Bohrer Alan; Bao Shunzhong; Song Haowei; Ramanadham Sasanka
The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
Bao Shunzhong; Li Yankun; Lei Xiaoyong; Wohltmann Mary; Jin Wu; Bohrer Alan; Semenkovich Clay F; Ramanadham Sasanka; Tabas Ira; Turk John
Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.

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All Publications

2008: Bao Shunzhong; Jacobson David A; Wohltmann Mary; Bohrer Alan; Jin Wu; Philipson Louis H; Turk John
Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
American journal of physiology. Endocrinology and metabolism 2008;294(2):E217-29.
2007: Lei Xiaoyong; Zhang Sheng; Bohrer Alan; Bao Shunzhong; Song Haowei; Ramanadham Sasanka
The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.
Biochemistry 2007;46(35):10170-85.
2007: Bao Shunzhong; Li Yankun; Lei Xiaoyong; Wohltmann Mary; Jin Wu; Bohrer Alan; Semenkovich Clay F; Ramanadham Sasanka; Tabas Ira; Turk John
Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.
The Journal of biological chemistry 2007;282(37):27100-14.
2006: Bao Shunzhong; Song Haowei; Wohltmann Mary; Ramanadham Sasanka; Jin Wu; Bohrer Alan; Turk John
Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.
The Journal of biological chemistry 2006;281(30):20958-73.
2006: Song Haowei; Bao Shunzhong; Ramanadham Sasanka; Turk John
Effects of biological oxidants on the catalytic activity and structure of group VIA phospholipase A2.
Biochemistry 2006;45(20):6392-406.
2006: Song Haowei; Ramanadham Sasanka; Bao Shunzhong; Hsu Fong-Fu; Turk John
A bromoenol lactone suicide substrate inactivates group VIA phospholipase A2 by generating a diffusible bromomethyl keto acid that alkylates cysteine thiols.
Biochemistry 2006;45(3):1061-73.
2006: Bao Shunzhong; Bohrer Alan; Ramanadham Sasanka; Jin Wu; Zhang Sheng; Turk John
Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.
The Journal of biological chemistry 2006;281(1):187-98.
2005: Wang Zhepeng; Ramanadham Sasanka; Ma Zhongmin Alex; Bao Shunzhong; Mancuso David J; Gross Richard W; Turk John
Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells.
The Journal of biological chemistry 2005;280(8):6840-9.
2004: Bao Shunzhong; Miller David J; Ma Zhongmin; Wohltmann Mary; Eng Grace; Ramanadham Sasanka; Moley Kelle; Turk John
Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.
The Journal of biological chemistry 2004;279(37):38194-200.
2004: Ramanadham Sasanka; Hsu Fong-Fu; Zhang Sheng; Jin Chun; Bohrer Alan; Song Haowei; Bao Shunzhong; Ma Zhongmin; Turk John
Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta.
Biochemistry 2004;43(4):918-30.
2003: Ramanadham Sasanka; Song Haowei; Hsu Fong-Fu; Zhang Sheng; Crankshaw Mark; Grant Gregory A; Newgard Christopher B; Bao Shunzhong; Ma Zhongmin; Turk John
Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.
Biochemistry 2003;42(47):13929-40.

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