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Eduardo Lazarowski

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Chemicals & Drugs

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Juliana I Sesma; Natacha Steinckwich-Besancon; Hong Dang; Rafael García-Mata; T Kendall Harden; Silvia M Kreda; Eduardo R Lazarowski
The UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.
Eduardo R Lazarowski
Vesicular and conductive mechanisms of nucleotide release.
Jianfeng Xu; Yaël Mamane; Joseph A Mancini; Andrea R Nawrocki; Eduardo R Lazarowski; Pingping Li; Hidetaka Morinaga; Dayoung Oh; Jerrold M Olefsky; Saswata Talukdar; Ai Chen; Jane J Kim
GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity.

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2012: Juliana I Sesma; Natacha Steinckwich-Besancon; Hong Dang; Rafael García-Mata; T Kendall Harden; Silvia M Kreda; Eduardo R Lazarowski
The UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.
American journal of physiology. Cell physiology 2012;303(5):C490-8.
2012: Eduardo R Lazarowski
Vesicular and conductive mechanisms of nucleotide release.
Purinergic signalling 2012;8(3):359-73.
2012: Jianfeng Xu; Yaël Mamane; Joseph A Mancini; Andrea R Nawrocki; Eduardo R Lazarowski; Pingping Li; Hidetaka Morinaga; Dayoung Oh; Jerrold M Olefsky; Saswata Talukdar; Ai Chen; Jane J Kim
GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(4):1992-9.
2012: Taiji Tsunemi; Travis D Ashe; Jonathan Au; Vincent A Damian; Eduardo R Lazarowski; Eliezer Masliah; Bradley E Morrison; Ruben A Vázquez Roque; Kathryn R Soriano; Albert R La Spada
PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
Science translational medicine 2012;4(142):142ra97.
2012: Lisa C Jones; Richard C Boucher; M Leslie Fulcher; Elizabeth J Hudson; Eduardo R Lazarowski; Lama Moussa; Wanda O Neal; Scott H Randell; Yunxiang Zhu; Silvia M Kreda
VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells.
The Journal of physiology 2012;590(Pt 3):545-62.
2012: Jean-Marc Tadie; Victor J Thannickal; Edward Abraham; Hong Beom Bae; Celeste P Bell; David D Chaplin; Jessy Deshane; Eduardo R Lazarowski; Jaroslaw W Zmijewski
Toll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanism.
Molecular medicine (Cambridge, Mass.) 2012;18():659-68.
2011: Nicolas Montalbetti; Omar P Pignataro; Eiry Kobatake; Eduardo R Lazarowski; Maria F Leal Denis; Pablo J Schwarzbaum
Homeostasis of extracellular ATP in human erythrocytes.
The Journal of biological chemistry 2011;286(44):38397-407.
2011: Seiko F Okada; Raymond J Pickles; Liqun Zhang; Lubna H Abdullah; C William Davis; Silvia M Kreda; Eduardo R Lazarowski; Richard C Boucher
Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium.
American journal of respiratory cell and molecular biology 2011;45(2):253-60.
2011: Lucia Seminario-Vidal; Juliana I Sesma; Catharina A van Heusden; Yunxiang Zhu; Richard C Boucher; Lisa C Jones; Silvia M Kreda; Dale W Laird; Seiko F Okada; Wanda O Neal; Silvia Penuela; Eduardo R Lazarowski
Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia.
The Journal of biological chemistry 2011;286(30):26277-86.
2011: Eduardo R Lazarowski; Juliana I Sesma; Lucia Seminario-Vidal; Silvia M Kreda
Molecular mechanisms of purine and pyrimidine nucleotide release.
Advances in pharmacology (San Diego, Calif.) 2011;61():221-61.
2011: Guilherme J M Garcia; Maryse Picher; Peiying Zuo; Seiko F Okada; Eduardo R Lazarowski; Brian Button; Richard C Boucher; Timothy C Elston
Computational model for the regulation of extracellular ATP and adenosine in airway epithelia.
Sub-cellular biochemistry 2011;55():51-74.
2011: Eduardo R Lazarowski; Juliana I Sesma; Lucia Seminario; Charles R Esther; Silvia M Kreda
Nucleotide release by airway epithelia.
Sub-cellular biochemistry 2011;55():1-15.
2010: Jaroslaw W Zmijewski; Sami Banerjee; Hongbeom Bae; Arnaud Friggeri; Eduardo R Lazarowski; Edward Abraham
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.
The Journal of biological chemistry 2010;285(43):33154-64.
2010: Faraaz B Chekeni; Michael Elliott; Joanna K Sandilos; Scott F Walk; Jason M Kinchen; Eduardo R Lazarowski; Allison J Armstrong; Silvia Penuela; Dale W Laird; Guy S Salvesen; Brant E Isakson; Douglas A Bayliss; Kodi S Ravichandran
Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis.
Nature 2010;467(7317):863-7.
2010: Silvia M Kreda; Lucia Seminario-Vidal; Catharina A van Heusden; Wanda O Neal; Lisa Jones; Richard C Boucher; Eduardo R Lazarowski
Receptor-promoted exocytosis of airway epithelial mucin granules containing a spectrum of adenine nucleotides.
The Journal of physiology 2010;588(Pt 12):2255-67.
2010: T Kendall Harden; J I Sesma; I P Fricks; Eduardo R Lazarowski
Signalling and pharmacological properties of the P2Y receptor.
Acta physiologica (Oxford, England) 2010;199(2):149-60.
2010: Eduardo R Lazarowski
Quantification of extracellular UDP-galactose.
Analytical biochemistry 2010;396(1):23-9.
2010: Ceila Loughlin; Charles R Esther; Eduardo R Lazarowski; Neil E Alexis; David Peden
Neutrophilic inflammation is associated with altered airway hydration in stable asthmatics.
Respiratory medicine 2010;104(1):29-33.
2009: Rhonda L Carter; Ingrid P Fricks; Matthew O Barrett; Lauren E Burianek; Yixing Zhou; Hyojin Ko; Arijit Das; Kenneth Alan Jacobson; Eduardo R Lazarowski; T Kendall Harden
Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor.
Molecular pharmacology 2009;76(6):1341-8.
2009: Michael R Elliott; Faraaz B Chekeni; Paul Trampont; Eduardo R Lazarowski; Alexandra Kadl; Scott F Walk; Daeho Park; Robin I Woodson; Marina Ostankovich; Poonam Sharma; Jeffrey J Lysiak; T Kendall Harden; Norbert Leitinger; Kodi S Ravichandran
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance.
Nature 2009;461(7261):282-6.
2009: Lucia Seminario-Vidal; Silvia M Kreda; Lisa Jones; Wanda O Neal; JoAnn Trejo; Richard C Boucher; Eduardo R Lazarowski
Thrombin promotes release of ATP from lung epithelial cells through coordinated activation of rho- and Ca2+-dependent signaling pathways.
The Journal of biological chemistry 2009;284(31):20638-48.
2009: Ingrid Fricks; Rhonda L Carter; Eduardo R Lazarowski; T Kendall Harden
Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems.
The Journal of pharmacology and experimental therapeutics 2009;330(1):162-8.
2009: Eduardo R Lazarowski; Richard C Boucher
Purinergic receptors in airway epithelia.
Current opinion in pharmacology 2009;9(3):262-7.
2009: Juliana I Sesma; Charles R Esther; Silvia M Kreda; Lisa Jones; Wanda O Neal; Shoko Nishihara; Robert A Nicholas; Eduardo R Lazarowski
Endoplasmic reticulum/golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling molecules.
The Journal of biological chemistry 2009;284(18):12572-83.
2009: Lucia Seminario-Vidal; Eduardo R Lazarowski; Seiko F Okada
Assessment of extracellular ATP concentrations.
Methods in molecular biology (Clifton, N.J.) 2009;574():25-36.
2009: Eduardo R Lazarowski; Pablo J Schwarzbaum
[Purinergic signals].
Medicina 2009;69(2):267-76.
2008: C William Davis; Eduardo R Lazarowski
Coupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling.
Respiratory physiology & neurobiology 2008;163(1-3):208-13.
2008: Kendra E Wolk; Eduardo R Lazarowski; Zachary P Traylor; Erin N Z Yu; Nancy A Jewell; Russell K Durbin; Joan E Durbin; Ian C Davis
Influenza A virus inhibits alveolar fluid clearance in BALB/c mice.
American journal of respiratory and critical care medicine 2008;178(9):969-76.
2008: Peiying Zuo; Maryse Picher; Seiko F Okada; Eduardo R Lazarowski; Brian Button; Richard C Boucher; Timothy C Elston
Mathematical model of nucleotide regulation on airway epithelia. Implications for airway homeostasis.
The Journal of biological chemistry 2008;283(39):26805-19.
2008: Charles R Esther; Juliana I Sesma; Henrik G Dohlman; Addison D Ault; Marién L Clas; Eduardo R Lazarowski; Richard C Boucher
Similarities between UDP-glucose and adenine nucleotide release in yeast: involvement of the secretory pathway.
Biochemistry 2008;47(35):9269-78.
2008: Charles R Esther; Neil E Alexis; M L Clas; Eduardo R Lazarowski; Scott H Donaldson; Carla M Pedrosa Ribeiro; Charity G Moore; Stephanie D Davis; Richard C Boucher
Extracellular purines are biomarkers of neutrophilic airway inflammation.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;31(5):949-56.
2008: Ingrid Fricks; Savitri Maddileti; Rhonda L Carter; Eduardo R Lazarowski; Robert A Nicholas; Kenneth Alan Jacobson; T Kendall Harden
UDP is a competitive antagonist at the human P2Y14 receptor.
The Journal of pharmacology and experimental therapeutics 2008;325(2):588-94.
2008: Silvia M Kreda; L Seminario-Vidal; C van Heusden; Eduardo R Lazarowski
Thrombin-promoted release of UDP-glucose from human astrocytoma cells.
British journal of pharmacology 2008;153(7):1528-37.
2007: Silvia M Kreda; Seiko F Okada; Catharina A van Heusden; Wanda O Neal; Sherif E Gabriel; Lubna H Abdullah; C William Davis; Richard C Boucher; Eduardo R Lazarowski
Coordinated release of nucleotides and mucin from human airway epithelial Calu-3 cells.
The Journal of physiology 2007;584(Pt 1):245-59.
2007: Ian C Davis; Eduardo R Lazarowski; Fu-Ping Chen; Judy M Hickman-Davis; Wayne M Sullender; Sadis Matalon
Post-infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection.
American journal of respiratory cell and molecular biology 2007;37(4):379-86.
2007: Andrew J Hirsh; Jaclyn R Stonebraker; Catharina A van Heusden; Eduardo R Lazarowski; Richard C Boucher; Maryse Picher
Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.
Biochemistry 2007;46(36):10373-83.
2006: Patrick Weydt; Victor V Pineda; Anne E Torrence; Randell T Libby; Terrence F Satterfield; Eduardo R Lazarowski; Merle L Gilbert; Gregory J Morton; Theodor K Bammler; Andrew D Strand; Libin Cui; Richard P Beyer; Courtney N Easley; Annette C Smith; Dimitri Krainc; Serge Luquet; Ian R Sweet; Michael W Schwartz; Albert R La Spada
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Cell metabolism 2006;4(5):349-62.
2006: Seiko F Okada; Robert A Nicholas; Silvia M Kreda; Eduardo R Lazarowski; Richard C Boucher
Physiological regulation of ATP release at the apical surface of human airway epithelia.
The Journal of biological chemistry 2006;281(32):22992-3002.
2006: Anna-Karin Wihlborg; Johanna Balogh; Lingwei Wang; Catharina Borna; Ying Dou; Bhalchandra V Joshi; Eduardo R Lazarowski; Kenneth Alan Jacobson; Anders Arner; David Erlinge
Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction.
Circulation research 2006;98(7):970-6.
2006: Ian C Davis; Eduardo R Lazarowski; Judy M Hickman-Davis; James A Fortenberry; Fu-Ping Chen; Xiaodong Zhao; Eric J Sorscher; Lee M Graves; Wayne M Sullender; Sadis Matalon
Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus.
American journal of respiratory and critical care medicine 2006;173(6):673-82.
2006: Eduardo R Lazarowski
Regulated release of nucleotides and UDP sugars from astrocytoma cells.
Novartis Foundation symposium 2006;276():73-84; discussion 84-90, 107-12, 275-81.
2005: Robert Tarran; Brian Button; Maryse Picher; Anthony M Paradiso; Carla M Pedrosa Ribeiro; Eduardo R Lazarowski; Liqun Zhang; Peter L Collins; Raymond J Pickles; Jeffrey J Fredberg; Richard C Boucher
Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections.
The Journal of biological chemistry 2005;280(42):35751-9.
2005: Catharina Borna; Eduardo R Lazarowski; Catharina van Heusden; Hans Ohlin; David Erlinge
Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels.
Thrombosis journal 2005;3():10.
2005: David Erlinge; Jan Harnek; Catharina van Heusden; Goran Olivecrona; Sverker Jern; Eduardo R Lazarowski
Uridine triphosphate (UTP) is released during cardiac ischemia.
International journal of cardiology 2005;100(3):427-33.
2005: Christelle D Douillet; William P Robinson; Ben L Zarzaur; Eduardo R Lazarowski; Richard C Boucher; Preston B Rich
Mechanical ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organs.
American journal of respiratory cell and molecular biology 2005;32(1):52-8.
2004: Seiko F Okada; Wanda O Neal; Pingbo Huang; Robert A Nicholas; Lawrence E Ostrowski; William J Craigen; Eduardo R Lazarowski; Richard C Boucher
Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells.
The Journal of general physiology 2004;124(5):513-26.
2004: Eduardo R Lazarowski; Robert Tarran; Barbara R Grubb; Catharina A van Heusden; Seiko Okada; Richard C Boucher
Nucleotide release provides a mechanism for airway surface liquid homeostasis.
The Journal of biological chemistry 2004;279(35):36855-64.
2004: Jozef Spychala; Eduardo R Lazarowski; Anna Ostapkowicz; Lanier H Ayscue; Aiwen Jin; Beverly S Mitchell
Role of estrogen receptor in the regulation of ecto-5'-nucleotidase and adenosine in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(2):708-17.
2003: Eduardo R Lazarowski; Richard C Boucher; T Kendall Harden
Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules.
Molecular pharmacology 2003;64(4):785-95.
2003: Eduardo R Lazarowski; Deborah A Shea; Richard C Boucher; T Kendall Harden
Release of cellular UDP-glucose as a potential extracellular signaling molecule.
Molecular pharmacology 2003;63(5):1190-7.
2002: Mingyan Hou; T Kendall Harden; Cynthia M Kuhn; Bo Baldetorp; Eduardo R Lazarowski; William Pendergast; Sebastian Möller; Lars Edvinsson; David Erlinge
UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y(6) receptors.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H784-92.
2001: P Huang; Eduardo R Lazarowski; Robert Tarran; Sharon L Milgram; Richard C Boucher; Monroe Stutts
Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):14120-5.
2001: Eduardo R Lazarowski; L G Rochelle; Wanda O Neal; Carla M Pedrosa Ribeiro; Barbara R Grubb; V Zhang; T Kendall Harden; Richard C Boucher
Cloning and functional characterization of two murine uridine nucleotide receptors reveal a potential target for correcting ion transport deficiency in cystic fibrosis gallbladder.
The Journal of pharmacology and experimental therapeutics 2001;297(1):43-9.
2001: Eduardo R Lazarowski; Richard C Boucher
UTP as an extracellular signaling molecule.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2001;16():1-5.
2000: Scott H Donaldson; Eduardo R Lazarowski; Maryse Picher; Michael Knowles; Monroe Stutts; Richard C Boucher
Basal nucleotide levels, release, and metabolism in normal and cystic fibrosis airways.
Molecular medicine (Cambridge, Mass.) 2000;6(11):969-82.
2000: Eduardo R Lazarowski; Richard C Boucher; T Kendall Harden
Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations.
The Journal of biological chemistry 2000;275(40):31061-8.
2000: Ronald D Graff; Eduardo R Lazarowski; Albert J Banes; Greta M Lee
ATP release by mechanically loaded porcine chondrons in pellet culture.
Arthritis and rheumatism 2000;43(7):1571-9.
2000: Silvia M Kreda; Raymond J Pickles; Eduardo R Lazarowski; Richard C Boucher
G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands.
Nature biotechnology 2000;18(6):635-40.
2000: Lee M Graves; Hedeel I Guy; P Kozlowski; Min Huang; Eduardo R Lazarowski; Marshall pope; M A Collins; E N Dahlstrand; Henry Earp; David R Evans
Regulation of carbamoyl phosphate synthetase by MAP kinase.
Nature 2000;403(6767):328-32.
1999: Victoria L Cressman; Eduardo R Lazarowski; L Homolya; Richard C Boucher; Beverly H Koller; Barbara R Grubb
Effect of loss of P2Y(2) receptor gene expression on nucleotide regulation of murine epithelial Cl(-) transport.
The Journal of biological chemistry 1999;274(37):26461-8.
1999: L Homolya; WC Watt; Eduardo R Lazarowski; Beverly H Koller; Richard C Boucher
Nucleotide-regulated calcium signaling in lung fibroblasts and epithelial cells from normal and P2Y(2) receptor (-/-) mice.
The Journal of biological chemistry 1999;274(37):26454-60.
1999: Eduardo R Lazarowski; T Kendall Harden
Quantitation of extracellular UTP using a sensitive enzymatic assay.
British journal of pharmacology 1999;127(5):1272-8.
1999: T Kendall Harden; Eduardo R Lazarowski
Release of ATP and UTP from astrocytoma cells.
Progress in brain research 1999;120():135-43.
1998: WC Watt; Eduardo R Lazarowski; Richard C Boucher
Cystic fibrosis transmembrane regulator-independent release of ATP. Its implications for the regulation of P2Y2 receptors in airway epithelia.
The Journal of biological chemistry 1998;273(22):14053-8.
1997: Eduardo R Lazarowski; L Homolya; Richard C Boucher; T Kendall Harden
Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation.
The Journal of biological chemistry 1997;272(39):24348-54.
1997: Eduardo R Lazarowski; L Homolya; Richard C Boucher; T Kendall Harden
Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists.
The Journal of biological chemistry 1997;272(33):20402-7.
1997: Eduardo R Lazarowski; Anthony M Paradiso; WC Watt; T Kendall Harden; Richard C Boucher
UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y2 receptor.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2599-603.
1997: T Kendall Harden; Eduardo R Lazarowski; Richard C Boucher
Release, metabolism and interconversion of adenine and uridine nucleotides: implications for G protein-coupled P2 receptor agonist selectivity.
Trends in pharmacological sciences 1997;18(2):43-6.
1996: Robert A Nicholas; Eduardo R Lazarowski; W C Watt; Q Li; J Boyer; T Kendall Harden
Pharmacological and second messenger signalling selectivities of cloned P2Y receptors.
Journal of autonomic pharmacology 1996;16(6):319-23.
1996: Robert A Nicholas; W C Watt; Eduardo R Lazarowski; Q Li; T Kendall Harden
Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.
Molecular pharmacology 1996;50(2):224-9.
1996: Eduardo R Lazarowski; W C Watt; Monroe Stutts; H A Brown; Richard C Boucher; T Kendall Harden
Enzymatic synthesis of UTP gamma S, a potent hydrolysis resistant agonist of P2U-purinoceptors.
British journal of pharmacology 1996;117(1):203-9.
1995: Anthony M Paradiso; S J Mason; Eduardo R Lazarowski; Richard C Boucher
Membrane-restricted regulation of Ca2+ release and influx in polarized epithelia.
Nature 1995;377(6550):643-6.
1995: Eduardo R Lazarowski; W C Watt; Monroe Stutts; Richard C Boucher; T Kendall Harden
Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate.
British journal of pharmacology 1995;116(1):1619-27.
1995: Monroe Stutts; Eduardo R Lazarowski; Anthony M Paradiso; Richard C Boucher
Activation of CFTR Cl- conductance in polarized T84 cells by luminal extracellular ATP.
The American journal of physiology 1995;268(2 Pt 1):C425-33.
1994: C E Parr; DM Sullivan; Anthony M Paradiso; Eduardo R Lazarowski; L H Burch; John C Olsen; Laurie Erb; Gary A Weisman; Richard C Boucher; John T Turner
Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):13067.
1994: Eduardo R Lazarowski; T Kendall Harden
Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C.
The Journal of biological chemistry 1994;269(16):11830-6.
1994: C E Parr; DM Sullivan; Anthony M Paradiso; Eduardo R Lazarowski; L H Burch; John C Olsen; Laurie Erb; Gary A Weisman; Richard C Boucher; John T Turner
Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3275-9.
1994: Eduardo R Lazarowski; Richard C Boucher; T Kendall Harden
Calcium-dependent release of arachidonic acid in response to purinergic receptor activation in airway epithelium.
The American journal of physiology 1994;266(2 Pt 1):C406-15.
1993: José L Boyer; Eduardo R Lazarowski; X H Chen; T Kendall Harden
Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1140-6.
1993: James R Yankaskas; J E Haizlip; M Conrad; D Koval; Eduardo R Lazarowski; Anthony M Paradiso; C A Rinehart; Balázs Sarkadi; R Schlegel; Richard C Boucher
Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype.
The American journal of physiology 1993;264(5 Pt 1):C1219-30.
1993: Barbara R Grubb; Eduardo R Lazarowski; Michael Knowles; Richard C Boucher
Isobutylmethylxanthine fails to stimulate chloride secretion in cystic fibrosis airway epithelia.
American journal of respiratory cell and molecular biology 1993;8(4):454-60.
1992: J Bauer; M Margolis; C Schreiner; Cora-Jean S Edgell; JC Azizkhan; Eduardo R Lazarowski; Rudy L Juliano
In vitro model of angiogenesis using a human endothelium-derived permanent cell line: contributions of induced gene expression, G-proteins, and integrins.
Journal of cellular physiology 1992;153(3):437-49.
1992: Eduardo R Lazarowski; S J Mason; L Clarke; T Kendall Harden; Richard C Boucher
Adenosine receptors on human airway epithelia and their relationship to chloride secretion.
British journal of pharmacology 1992;106(4):774-82.
1992: A J Daniels; J E Matthews; O Humberto Viveros; Eduardo R Lazarowski
Characterization of the neuropeptide Y-induced intracellular calcium release in human erythroleukemic cells.
Molecular pharmacology 1992;41(4):767-71.
1991: H A Brown; Eduardo R Lazarowski; Richard C Boucher; T Kendall Harden
Evidence that UTP and ATP regulate phospholipase C through a common extracellular 5'-nucleotide receptor in human airway epithelial cells.
Molecular pharmacology 1991;40(5):648-55.
1990: Eduardo R Lazarowski; Deborah Winegar; R D Nolan; E Oberdisse; E G Lapetina
Effect of protein kinase A on inositide metabolism and rap 1 G-protein in human erythroleukemia cells.
The Journal of biological chemistry 1990;265(22):13118-23.
1990: Eduardo R Lazarowski; E G Lapetina
Persistent activation of platelet membrane phospholipase C by proteolytic action of trypsin and thrombin.
Archives of biochemistry and biophysics 1990;276(1):265-9.
1989: A J Daniels; Eduardo R Lazarowski; J E Matthews; E G Lapetina
Neuropeptide Y mobilizes intracellular Ca2+ and increases inositol phosphate production in human erythroleukemia cells.
Biochemical and biophysical research communications 1989;165(3):1138-44.
1989: Eduardo R Lazarowski; J C Lacal; E G Lapetina
Agonist-induced phosphorylation of an immunologically ras-related protein in human erythroleukemia cells.
Biochemical and biophysical research communications 1989;161(3):972-8.
1989: Eduardo R Lazarowski; E G Lapetina
Activation of platelet phospholipase C by fluoride is inhibited by elevation of cyclic AMP.
Biochemical and biophysical research communications 1989;158(2):440-4.
1986: Eduardo R Lazarowski; J A Santomé; N H Behrens; J C Sanchez Avalos
Aggregation of human neutrophils by heparin.
Thrombosis research 1986;41(4):437-46.