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Brooke Lazarus

Research Profile

Chemicals & Drugs

Phenomena

Glycosylation

Physiology

Genes & Molecular Sequences

Concepts & Ideas

Disorders

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Publications

TOP 3
Peng Wang; Michele E Forsythe; Michael W Krause; Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.
Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling: implications for neurodegenerative disorders.
Michele E Forsythe; Dona C Love; Brooke D Lazarus; Eun Ju Kim; William A Prinz; Gilbert Ashwell; Michael W Krause; John Hanover
Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.

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All Publications

2012: Peng Wang; Michele E Forsythe; Michael W Krause; Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(43):17669-74.
2009: Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling: implications for neurodegenerative disorders.
The international journal of biochemistry & cell biology 2009;41(11):2134-46.
2006: Michele E Forsythe; Dona C Love; Brooke D Lazarus; Eun Ju Kim; William A Prinz; Gilbert Ashwell; Michael W Krause; John Hanover
Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):11952-7.
2006: Brooke D Lazarus; Dona C Love; John Hanover
Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates.
Glycobiology 2006;16(5):415-21.
2005: Brooke D Lazarus; Mark D Roos; John Hanover
Mutational analysis of the catalytic domain of O-linked N-acetylglucosaminyl transferase.
The Journal of biological chemistry 2005;280(42):35537-44.
2004: Martin Jínek; Jan Rehwinkel; Brooke D Lazarus; Elisa Izaurralde; John Hanover; Elena Conti
The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha.
Nature structural & molecular biology 2004;11(10):1001-7.

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