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Stephen Lazarus

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Kelly Wong McGrath; E Rand Sutherland; Homer A Boushey; Vernon M Chinchilli; John V Fahy; Nikolina Icitovic; Stephen C Lazarus
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic.
Prescott G Woodruff; Richard K Albert; William C Bailey; Richard Casaburi; John E Connett; John A D Cooper; Gerard J Criner; Jeffrey L Curtis; Mark T Dransfield; Meilan K Han; Sarah M Harnden; Victor Kim; Nathaniel Marchetti; Fernando J Martinez; Charlene E McEvoy; Dennis E Niewoehner; John J Reilly; Kathryn Rice; Paul D Scanlon; Steven M Scharf; Frank C Sciurba; George R Washko; Stephen C Lazarus
Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization.
Susan Janson; Kelly Wong McGrath; Jack K Covington; Robert B Baron; Stephen C Lazarus
Objective airway monitoring improves asthma control in the cold and flu season: a cluster randomized trial.

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2012: Kelly Wong McGrath; E Rand Sutherland; Homer A Boushey; Vernon M Chinchilli; John V Fahy; Nikolina Icitovic; Stephen C Lazarus
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic.
American journal of respiratory and critical care medicine 2012;185(6):612-9.
2011: Prescott G Woodruff; Richard K Albert; William C Bailey; Richard Casaburi; John E Connett; John A D Cooper; Gerard J Criner; Jeffrey L Curtis; Mark T Dransfield; Meilan K Han; Sarah M Harnden; Victor Kim; Nathaniel Marchetti; Fernando J Martinez; Charlene E McEvoy; Dennis E Niewoehner; John J Reilly; Kathryn Rice; Paul D Scanlon; Steven M Scharf; Frank C Sciurba; George R Washko; Stephen C Lazarus
Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization.
COPD 2011;8(1):21-9.
2010: Susan Janson; Kelly Wong McGrath; Jack K Covington; Robert B Baron; Stephen C Lazarus
Objective airway monitoring improves asthma control in the cold and flu season: a cluster randomized trial.
Chest 2010;138(5):1148-55.
2010: Stephen C Lazarus
Clinical practice. Emergency treatment of asthma.
The New England journal of medicine 2010;363(8):755-64.
2009: Erin Gordon; Stephen C Lazarus
Management of chronic obstructive pulmonary disease: moving beyond the asthma algorithm.
The Journal of allergy and clinical immunology 2009;124(5):873-80; quiz 881-2.
2007: Stephen C Lazarus; Vernon M Chinchilli; Nancy J Rollings; Homer A Boushey; Reuben M Cherniack; Timothy J Craig; Aaron Deykin; Emily DiMango; James E Fish; Jean G Ford; Elliot Israel; James P Kiley; Monica Kraft; Robert F Lemanske; Frank T Leone; Richard J Martin; Gene R Pesola; Stephen P Peters; Christine A Sorkness; Stanley J Szefler; Michael E Wechsler; John V Fahy
Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma.
American journal of respiratory and critical care medicine 2007;175(8):783-90.
2007: Aaron Deykin; Michael E Wechsler; Homer A Boushey; Vernon M Chinchilli; Susan J Kunselman; Timothy J Craig; Emily DiMango; John V Fahy; Monica Kraft; Frank Leone; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Gene R Pesola; Stephen P Peters; Christine A Sorkness; Stanley J Szefler; Elliot Israel
Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma.
American journal of respiratory and critical care medicine 2007;175(3):228-34.
2007: Richard J Martin; Stanley J Szefler; Tonya S King; Monica Kraft; Homer A Boushey; Vernon M Chinchilli; Timothy J Craig; Emily DiMango; Aaron Deykin; John V Fahy; Elliot Israel; Stephen C Lazarus; Robert F Lemanske; Frank T Leone; Gene R Pesola; Stephen P Peters; Christine A Sorkness; Lisa A Szwejbka; Michael E Wechsler
The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial.
The Journal of allergy and clinical immunology 2007;119(1):73-80.
2006: Anh L Innes; Prescott G Woodruff; Ronald E Ferrando; Samantha Donnelly; Gregory M Dolganov; Stephen C Lazarus; John V Fahy
Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction.
Chest 2006;130(4):1102-8.
2006: Stephen C Lazarus
Mild persistent asthma: is any treatment needed?
The Journal of allergy and clinical immunology 2006;118(4):805-8.
2006: Michael E Wechsler; Erik Lehman; Stephen C Lazarus; Robert F Lemanske; Homer A Boushey; Aaron Deykin; John V Fahy; Christine A Sorkness; Vernon M Chinchilli; Timothy J Craig; Emily DiMango; Monica Kraft; Frank Leone; Richard J Martin; Stephen P Peters; Stanley J Szefler; Wenlei Liu; Elliot Israel
beta-Adrenergic receptor polymorphisms and response to salmeterol.
American journal of respiratory and critical care medicine 2006;173(5):519-26.
2005: Homer A Boushey; Christine A Sorkness; Tonya S King; Sean D Sullivan; John V Fahy; Stephen C Lazarus; Vernon M Chinchilli; Timothy J Craig; Emily DiMango; Aaron Deykin; Joanne K Fagan; James E Fish; Jean G Ford; Monica Kraft; Robert F Lemanske; Frank T Leone; Richard J Martin; Elizabeth A Mauger; Gene R Pesola; Stephen P Peters; Nancy J Rollings; Stanley J Szefler; Michael E Wechsler; Elliot Israel
Daily versus as-needed corticosteroids for mild persistent asthma.
The New England journal of medicine 2005;352(15):1519-28.
2005: Aaron Deykin; Stephen C Lazarus; John V Fahy; Michael E Wechsler; Homer A Boushey; Vernon M Chinchilli; Timothy J Craig; Emily DiMango; Monica Kraft; Frank Leone; Robert F Lemanske; Richard J Martin; Gene R Pesola; Stephen P Peters; Christine A Sorkness; Stanley J Szefler; Elliot Israel
Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids.
The Journal of allergy and clinical immunology 2005;115(4):720-7.
2004: Elliot Israel; Vernon M Chinchilli; Jean G Ford; Homer A Boushey; Reuben M Cherniack; Timothy J Craig; Aaron Deykin; Joanne K Fagan; John V Fahy; James Fish; Monica Kraft; Susan J Kunselman; Stephen C Lazarus; Robert F Lemanske; Stephen B Liggett; Richard J Martin; Nandita Mitra; Stephen P Peters; Eric Silverman; Christine A Sorkness; Stanley J Szefler; Michael E Wechsler; Scott Weiss; Jeffrey M Drazen
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial.
Lancet 2004;364(9444):1505-12.
2003: Monica Kraft; Richard J Martin; Stephen C Lazarus; John V Fahy; Homer A Boushey; Robert F Lemanske; Stanley J Szefler
Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids.
Chest 2003;124(1):42-50.
2002: Richard J Martin; Stanley J Szefler; Vernon M Chinchilli; Monica Kraft; Myrna Dolovich; Homer A Boushey; Reuben M Cherniack; Timothy J Craig; Jeffrey M Drazen; Joanne K Fagan; John V Fahy; James E Fish; Jean G Ford; Elliot Israel; Susan J Kunselman; Stephen C Lazarus; Robert F Lemanske; Stephen P Peters; Christine A Sorkness
Systemic effect comparisons of six inhaled corticosteroid preparations.
American journal of respiratory and critical care medicine 2002;165(10):1377-83.
2002: Susan Janson; Stephen C Lazarus
Where do leukotriene modifiers fit in asthma management?
The Nurse practitioner 2002;27(4):19, 23-4, 26-9; quiz 30-1.
2002: Stanley J Szefler; Richard J Martin; Tonya S King; Homer A Boushey; Reuben M Cherniack; Vernon M Chinchilli; Timothy J Craig; Myrna Dolovich; Jeffrey M Drazen; Joanne K Fagan; John V Fahy; James E Fish; Jean G Ford; Elliot Israel; James P Kiley; Monica Kraft; Stephen C Lazarus; Robert F Lemanske; Elizabeth A Mauger; Stephen P Peters; Christine A Sorkness
Significant variability in response to inhaled corticosteroids for persistent asthma.
The Journal of allergy and clinical immunology 2002;109(3):410-8.
2001: Vernon M Chinchilli; Jeffrey M Drazen; James E Fish; Robert F Lemanske; Stephen C Lazarus; R J Martin
The clinical trials in the initial five-year award period of the Asthma Clinical Research Network.
Controlled clinical trials 2001;22(6 Suppl):126S-34S.
2001: Pierre-Régis Burgel; Stephen C Lazarus; Dominic Cheng-Wei Tam; Iris F Ueki; Kamran Atabai; M Birch; Jay A Nadel
Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5948-54.
2001: Prescott G Woodruff; R Khashayar; Stephen C Lazarus; Susan Janson; Pedro C Avila; Homer A Boushey; M Segal; John V Fahy
Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma.
The Journal of allergy and clinical immunology 2001;108(5):753-8.
2001: Robert F Lemanske; Christine A Sorkness; Elizabeth A Mauger; Stephen C Lazarus; Homer A Boushey; John V Fahy; Jeffrey M Drazen; Vernon M Chinchilli; T Craig; James E Fish; Jean G Ford; Elliot Israel; Monica Kraft; Richard J Martin; Sharon Nachman; Stephen P Peters; Joseph D Spahn; Stanley J Szefler
Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2001;285(20):2594-603.
2001: Stephen C Lazarus; Homer A Boushey; John V Fahy; Vernon M Chinchilli; Robert F Lemanske; Christine A Sorkness; Monica Kraft; James E Fish; Stephen P Peters; T Craig; Jeffrey M Drazen; Jean G Ford; Elliot Israel; Richard J Martin; Elizabeth A Mauger; Sharon Nachman; Joseph D Spahn; Stanley J Szefler
Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2001;285(20):2583-93.
2001: John V Fahy; Homer A Boushey; Stephen C Lazarus; Elizabeth A Mauger; Reuben M Cherniack; Vernon M Chinchilli; Timothy J Craig; Jeffrey M Drazen; Jean G Ford; James E Fish; Elliot Israel; Monica Kraft; Robert F Lemanske; Richard J Martin; D McLean; Stephen P Peters; Christine A Sorkness; Stanley J Szefler
Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study.
American journal of respiratory and critical care medicine 2001;163(6):1470-5.
2001: Frank T Leone; Elizabeth A Mauger; Stephen P Peters; Vernon M Chinchilli; James E Fish; Homer A Boushey; Reuben M Cherniack; Jeffrey M Drazen; John V Fahy; Jean G Ford; Elliot Israel; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Stephen J McGeady; Christine A Sorkness; Stanley J Szefler
The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research.
Chest 2001;119(4):1027-33.
2001: Elliot Israel; Jeffrey M Drazen; Stephen B Liggett; Homer A Boushey; Reuben M Cherniack; Vernon M Chinchilli; Dan M Cooper; John V Fahy; James E Fish; Jean G Ford; Monica Kraft; Susan J Kunselman; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Diane E McLean; Stephen P Peters; Edwin K Silverman; Christine A Sorkness; Stanley J Szefler; Scott Weiss; CN Yandava
Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma.
International archives of allergy and immunology 2001;124(1-3):183-6.
2000: Elliot Israel; Jeffrey M Drazen; Stephen B Liggett; Homer A Boushey; Reuben M Cherniack; Vernon M Chinchilli; Dan M Cooper; John V Fahy; James E Fish; Jean G Ford; Monica Kraft; Susan J Kunselman; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Diane E McLean; Stephen P Peters; Edwin K Silverman; Christine A Sorkness; Stanley J Szefler; Scott Weiss; CN Yandava
The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma.
American journal of respiratory and critical care medicine 2000;162(1):75-80.
1999: Stephen C Lazarus
Antileukotrienes and laboratory models of asthma.
Clinical reviews in allergy & immunology 1999;17(1-2):223-33.
1999: H Liu; Stephen C Lazarus; George H Caughey; John V Fahy
Neutrophil elastase and elastase-rich cystic fibrosis sputum degranulate human eosinophils in vitro.
The American journal of physiology 1999;276(1 Pt 1):L28-34.
1998: Stephen C Lazarus
Inflammation, inflammatory mediators, and mediator antagonists in asthma.
Journal of clinical pharmacology 1998;38(7):577-82.
1997: Stephen C Lazarus; Hofer H Wong; M J Watts; Homer A Boushey; B J Lavins; M C Minkwitz
The leukotriene receptor antagonist zafirlukast inhibits sulfur dioxide-induced bronchoconstriction in patients with asthma.
American journal of respiratory and critical care medicine 1997;156(6):1725-30.
1997: James E Fish; Stephen P Peters; Christopher V Chambers; Stephen J McGeady; K R Epstein; Homer A Boushey; Reuben M Cherniack; Vernon M Chinchilli; Jeffrey M Drazen; John V Fahy; S S Hurd; Elliot Israel; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Elizabeth A Mauger; Christine A Sorkness; Stanley J Szefler
An evaluation of colchicine as an alternative to inhaled corticosteriods in moderate asthma. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network.
American journal of respiratory and critical care medicine 1997;156(4 Pt 1):1165-71.
1996: P S Thomas; D W Pennington; R E Schreck; T M Levine; Stephen C Lazarus
Authentic 17 kDa tumour necrosis factor alpha is synthesized and released by canine mast cells and up-regulated by stem cell factor.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(6):710-8.
1996: Kenneth C Fang; Wilfred W Raymond; Stephen C Lazarus; George H Caughey
Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase.
The Journal of clinical investigation 1996;97(7):1589-96.
1993: N Inase; T M Levine; Stephen C Lazarus
Mitogen-inducible prostaglandin G/H synthase is expressed in canine mastocytoma cells.
American journal of respiratory cell and molecular biology 1993;9(5):526-32.
1993: A B Baxter; Stephen C Lazarus; Robert C Brasch
In vitro histamine release induced by magnetic resonance imaging and iodinated contrast media.
Investigative radiology 1993;28(4):308-12.
1993: N Inase; R E Schreck; Stephen C Lazarus
Heparin inhibits histamine release from canine mast cells.
The American journal of physiology 1993;264(4 Pt 1):L387-90.
1992: P S Thomas; A N Wilson; R E Schreck; Stephen C Lazarus
Prostaglandin D2 production and identification of prostaglandin H synthase within canine mast cell granule.
The American journal of physiology 1992;263(2 Pt 1):L168-76.
1992: P S Thomas; R E Schreck; Stephen C Lazarus
Tobacco smoke releases performed mediators from canine mast cells and modulates prostaglandin production.
The American journal of physiology 1992;263(1 Pt 1):L67-72.
1991: Warren M Gold; Stephen C Lazarus
Mast cells and cell-to-cell interactions in airways.
The American review of respiratory disease 1991;143(3 Pt 2):S61-3.
1991: P S Thomas; R E Schreck; Stephen J Ruoss; Stephen C Lazarus
Heterogeneity of intact granules purified from canine mastocytoma cell lines.
The American journal of physiology 1991;260(2 Pt 1):L153-60.
1990: C P Sommerhoff; Molly L Osborne; Stephen C Lazarus
Effect of inhibitors on histamine release from mast cells recovered by bronchoalveolar lavage in basenji-greyhound and mongrel dogs.
Agents and actions 1990;31(3-4):183-9.
1989: M S Bernstein; Stephen C Lazarus
Diagnosis and management of asthma.
Comprehensive therapy 1989;15(12):53-60.
1989: C P Sommerhoff; George H Caughey; Walter E Finkbeiner; Stephen C Lazarus; Carol Basbaum; Jay A Nadel
Mast cell chymase. A potent secretagogue for airway gland serous cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(7):2450-6.
1989: G M Franconi; P D Graf; Stephen C Lazarus; Jay A Nadel; George H Caughey
Mast cell tryptase and chymase reverse airway smooth muscle relaxation induced by vasoactive intestinal peptide in the ferret.
The Journal of pharmacology and experimental therapeutics 1989;248(3):947-51.
1989: C P Sommerhoff; Molly L Osborne; Warren M Gold; Stephen C Lazarus
Functional and morphologic characterization of mast cells recovered by bronchoalveolar lavage from Basenji greyhound and mongrel dogs.
The Journal of allergy and clinical immunology 1989;83(2 Pt 1):441-9.
1989: K Sekizawa; George H Caughey; Stephen C Lazarus; Warren M Gold; Jay A Nadel
Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs.
The Journal of clinical investigation 1989;83(1):175-9.
1988: L S Forsberg; Stephen C Lazarus; N Seno; R DeVinney; George H Caughey; Warren M Gold
Dog mastocytoma proteoglycans: occurrence of heparin and oversulfated chondroitin sulfates, containing trisulfated disaccharides, in three cell lines.
Biochimica et biophysica acta 1988;967(3):416-28.
1988: K Barnett; David B Jacoby; Jay A Nadel; Stephen C Lazarus
The effects of epithelial cell supernatant on contractions of isolated canine tracheal smooth muscle.
The American review of respiratory disease 1988;138(4):780-3.
1988: George H Caughey; N F Viro; L D Calonico; Donald M McDonald; Stephen C Lazarus; Warren M Gold
Chymase and tryptase in dog mastocytoma cells: asynchronous expression as revealed by enzyme cytochemical staining.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1988;36(8):1053-60.
1988: S Varsano; Stephen C Lazarus; Warren M Gold; Jay A Nadel
Selective adhesion of mast cells to tracheal epithelial cells in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2184-92.
1988: George H Caughey; Stephen C Lazarus; N F Viro; Warren M Gold; Jay A Nadel
Tryptase and chymase: comparison of extraction and release in two dog mastocytoma lines.
Immunology 1988;63(2):339-44.
1988: George H Caughey; N F Viro; Stephen C Lazarus; Jay A Nadel
Purification and characterization of dog mastocytoma chymase: identification of an octapeptide conserved in chymotryptic leukocyte proteinases.
Biochimica et biophysica acta 1988;952(2):142-9.
1987: George H Caughey; N F Viro; J Ramachandran; Stephen C Lazarus; D B Borson; Jay A Nadel
Dog mastocytoma tryptase: affinity purification, characterization, and amino-terminal sequence.
Archives of biochemistry and biophysics 1987;258(2):555-63.
1987: Stephen C Lazarus; D B Borson; W M Gold; J A Nadel
Inflammatory mediators, tachykinins and enkephalinase in airways.
International archives of allergy and applied immunology 1987;82(3-4):372-6.
1986: Stephen C Lazarus; R DeVinney; L J McCabe; Walter E Finkbeiner; D J Elias; Warren M Gold
Isolated canine mastocytoma cells: propagation and characterization of two cell lines.
The American journal of physiology 1986;251(6 Pt 1):C935-44.
1986: Stephen C Lazarus; L J McCabe; Jay A Nadel; Warren M Gold; George Leikauf
Effects of mast cell-derived mediators on epithelial cells in canine trachea.
The American journal of physiology 1986;251(3 Pt 1):C387-94.