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Michel Lazdunski

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Amino Acid Sequence

Anatomy

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Ion Channel Gating

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Molecular Cloning

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Co-Publications
Name
55
Lesage, Florian
51
Romey, Georges
51
Barhanin, Jacques
43
Heurteaux, Catherine
40
Fosset, M
35
Honoré, Eric
34
de Weille, Jan
29
Duprat, Fabrice
29
Lingueglia, Eric
28
Barbry, Pascal
24
Lambeau, Gérard
23
Voilley, Nicolas
22
Waldmann, Rainer
22
Champigny, G
21
Lauritzen, Inger

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Publications

TOP 3
Salinas Miguel; Lazdunski Michel; Lingueglia Eric
Structural elements for the generation of sustained currents by the acid pain sensor ASIC3.
Sandoz Guillaume; Douguet Dominique; Chatelain Franck; Lazdunski Michel; Lesage Florian
Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.
Noël Jacques; Zimmermann Katharina; Busserolles Jérome; Deval Emanuel; Alloui Abdelkrim; Diochot Sylvie; Guy Nicolas; Borsotto Marc; Reeh Peter; Eschalier Alain; Lazdunski Michel
The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception.

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All Publications

2009: Salinas Miguel; Lazdunski Michel; Lingueglia Eric
Structural elements for the generation of sustained currents by the acid pain sensor ASIC3.
The Journal of biological chemistry 2009;284(46):31851-9.
2009: Sandoz Guillaume; Douguet Dominique; Chatelain Franck; Lazdunski Michel; Lesage Florian
Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14628-33.
2009: Noël Jacques; Zimmermann Katharina; Busserolles Jérome; Deval Emanuel; Alloui Abdelkrim; Diochot Sylvie; Guy Nicolas; Borsotto Marc; Reeh Peter; Eschalier Alain; Lazdunski Michel
The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception.
The EMBO journal 2009;28(9):1308-18.
2009: Ettaiche Mohammed; Deval Emmanuel; Pagnotta Sophie; Lazdunski Michel; Lingueglia Eric
Acid-sensing ion channel 3 in retinal function and survival.
Investigative ophthalmology & visual science 2009;50(5):2417-26.
2009: Diochot Sylvie; Lazdunski Michel
Sea anemone toxins affecting potassium channels.
Progress in molecular and subcellular biology 2009;46():99-122.
2008: Deval Emmanuel; Noël Jacques; Lay Nadège; Alloui Abdelkrim; Diochot Sylvie; Friend Valérie; Jodar Martine; Lazdunski Michel; Lingueglia Eric
ASIC3, a sensor of acidic and primary inflammatory pain.
The EMBO journal 2008;27(22):3047-55.
2008: Sandoz Guillaume; Tardy Magalie P; Thümmler Susanne; Feliciangeli Sylvain; Lazdunski Michel; Lesage Florian
Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(34):8545-52.
2008: Baron Anne; Voilley Nicolas; Lazdunski Michel; Lingueglia Eric
Acid sensing ion channels in dorsal spinal cord neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(6):1498-508.
2007: Chemin Jean; Patel Amanda Jane; Duprat Fabrice; Sachs Frederick; Lazdunski Michel; Honore Eric
Up- and down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids.
Pflügers Archiv : European journal of physiology 2007;455(1):97-103.
2007: Feliciangeli Sylvain; Bendahhou Saïd; Sandoz Guillaume; Gounon Pierre; Reichold Markus; Warth Richard; Lazdunski Michel; Barhanin Jacques; Lesage Florian
Does sumoylation control K2P1/TWIK1 background K+ channels?
Cell 2007;130(3):563-9.
2007: Mazzuca Michel; Heurteaux Catherine; Alloui Abdelkrim; Diochot Sylvie; Baron Anne; Voilley Nicolas; Blondeau Nicolas; Escoubas Pierre; Gélot Agnès; Cupo Anny; Zimmer Andreas; Zimmer Anne M; Eschalier Alain; Lazdunski Michel
A tarantula peptide against pain via ASIC1a channels and opioid mechanisms.
Nature neuroscience 2007;10(8):943-5.
2007: Blondeau Nicolas; Pétrault Olivier; Manta Stella; Giordanengo Valérie; Gounon Pierre; Bordet Régis; Lazdunski Michel; Heurteaux Catherine
Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel.
Circulation research 2007;101(2):176-84.
2007: Garry Ambroise; Fromy Bérengère; Blondeau Nicolas; Henrion Daniel; Brau Frédéric; Gounon Pierre; Guy Nicolas; Heurteaux Catherine; Lazdunski Michel; Saumet Jean Louis
Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link.
EMBO reports 2007;8(4):354-9.
2007: Borsotto M; Cavarec L; Bouillot M; Romey G; Macciardi F; Delaye A; Nasroune M; Bastucci M; Sambucy J-L; Luan J-J; Charpagne A; Jouët V; Léger R; Lazdunski M; Cohen D; Chumakov I
PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder.
The pharmacogenomics journal 2007;7(2):123-32.
2007: Thümmler Susanne; Duprat Fabrice; Lazdunski Michel
Antipsychotics inhibit TREK but not TRAAK channels.
Biochemical and biophysical research communications 2007;354(1):284-9.
2007: Diochot S; Salinas M; Baron A; Escoubas P; Lazdunski M
Peptides inhibitors of acid-sensing ion channels.
Toxicon : official journal of the International Society on Toxinology 2007;49(2):271-84.
2006: Sandoz Guillaume; Thümmler Susanne; Duprat Fabrice; Feliciangeli Sylvain; Vinh Joëlle; Escoubas Pierre; Guy Nicolas; Lazdunski Michel; Lesage Florian
AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.
The EMBO journal 2006;25(24):5864-72.
2006: Zanzouri Marc; Lauritzen Inger; Lazdunski Michel; Patel Amanda
The background K(+) channel TASK-3 is regulated at both the transcriptional and post-transcriptional levels.
Biochemical and biophysical research communications 2006;348(4):1350-7.
2006: Heurteaux Catherine; Lucas Guillaume; Guy Nicolas; El Yacoubi Malika; Thümmler Susanne; Peng Xiao-Dong; Noble Florence; Blondeau Nicolas; Widmann Catherine; Borsotto Marc; Gobbi Gabriella; Vaugeois Jean-Marie; Debonnel Guy; Lazdunski Michel
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype.
Nature neuroscience 2006;9(9):1134-41.
2006: Zanzouri Marc; Lauritzen Inger; Duprat Fabrice; Mazzuca Michel; Lesage Florian; Lazdunski Michel; Patel Amanda
Membrane potential-regulated transcription of the resting K+ conductance TASK-3 via the calcineurin pathway.
The Journal of biological chemistry 2006;281(39):28910-8.
2006: Alloui Abdelkrim; Zimmermann Katharina; Mamet Julien; Duprat Fabrice; Noël Jacques; Chemin Jean; Guy Nicolas; Blondeau Nicolas; Voilley Nicolas; Rubat-Coudert Catherine; Borsotto Marc; Romey Georges; Heurteaux Catherine; Reeh Peter; Eschalier Alain; Lazdunski Michel
TREK-1, a K+ channel involved in polymodal pain perception.
The EMBO journal 2006;25(11):2368-76.
2006: Ettaiche Mohammed; Deval Emmanuel; Cougnon Marc; Lazdunski Michel; Voilley Nicolas
Silencing acid-sensing ion channel 1a alters cone-mediated retinal function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(21):5800-9.
2006: Rouault Morgane; Rash Lachlan D; Escoubas Pierre; Boilard Eric; Bollinger James; Lomonte Bruno; Maurin Thomas; Guillaume Carole; Canaan Stéphane; Deregnaucourt Christiane; Schrével Joseph; Doglio Alain; Gutiérrez José María; Lazdunski Michel; Gelb Michael H; Lambeau Gérard
Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity.
Biochemistry 2006;45(18):5800-16.
2006: Lingueglia Eric; Deval Emmanuel; Lazdunski Michel
FMRFamide-gated sodium channel and ASIC channels: a new class of ionotropic receptors for FMRFamide and related peptides.
Peptides 2006;27(5):1138-52.
2006: Restano-Cassulini Rita; Korolkova Yuliya V; Diochot Sylvie; Gurrola Georgina; Guasti Leonardo; Possani Lourival D; Lazdunski Michel; Grishin Eugene V; Arcangeli Annarosa; Wanke Enzo
Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system.
Molecular pharmacology 2006;69(5):1673-83.
2006: Bosmans Frank; Rash Lachlan; Zhu Shunyi; Diochot Sylvie; Lazdunski Michel; Escoubas Pierre; Tytgat Jan
Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes.
Molecular pharmacology 2006;69(2):419-29.
2006: Salinas Miguel; Rash Lachlan D; Baron Anne; Lambeau Gérard; Escoubas Pierre; Lazdunski Michel
The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a.
The Journal of physiology 2006;570(Pt 2):339-54.
2006: Deval Emmanuel; Friend Valérie; Thirant Cécile; Salinas Miguel; Jodar Martine; Lazdunski Michel; Lingueglia Eric
Regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein Na+/H+ exchanger regulatory factor-1.
The Journal of biological chemistry 2006;281(3):1796-807.
2006: Heurteaux C; Laigle C; Blondeau N; Jarretou G; Lazdunski M
Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia.
Neuroscience 2006;137(1):241-51.
2005: Chagot Benjamin; Escoubas Pierre; Diochot Sylvie; Bernard Cédric; Lazdunski Michel; Darbon Hervé
Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels.
Protein science : a publication of the Protein Society 2005;14(8):2003-10.
2005: Lauritzen Inger; Chemin Jean; Honoré Eric; Jodar Martine; Guy Nicolas; Lazdunski Michel; Jane Patel Amanda
Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton.
EMBO reports 2005;6(7):642-8.
2005: Chagot Benjamin; Diochot Sylvie; Pimentel Cyril; Lazdunski Michel; Darbon Hervé
Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: a new fold for an HERG toxin.
Proteins 2005;59(2):380-6.
2005: Chemin Jean; Patel Amanda; Duprat Fabrice; Zanzouri Marc; Lazdunski Michel; Honoré Eric
Lysophosphatidic acid-operated K+ channels.
The Journal of biological chemistry 2005;280(6):4415-21.
2005: Chemin Jean; Patel Amanda Jane; Duprat Fabrice; Lauritzen Inger; Lazdunski Michel; Honoré Eric
A phospholipid sensor controls mechanogating of the K+ channel TREK-1.
The EMBO journal 2005;24(1):44-53.
2005: Duprat F; Girard C; Jarretou G; Lazdunski M
Pancreatic two P domain K+ channels TALK-1 and TALK-2 are activated by nitric oxide and reactive oxygen species.
The Journal of physiology 2005;562(Pt 1):235-44.
2004: Decressac Sonia; Franco Michel; Bendahhou Said; Warth Richard; Knauer Sebastian; Barhanin Jacques; Lazdunski Michel; Lesage Florian
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6.
EMBO reports 2004;5(12):1171-5.
2004: Heurteaux C; Guy N; Laigle C; Blondeau N; Duprat F; Mazzuca M; Lang-Lazdunski L; Widmann C; Zanzouri M; Romey G; Lazdunski M
TREK-1, a K+ channel involved in neuroprotection and general anesthesia.
The EMBO journal 2004;23(13):2684-95.
2004: Roza Carolina; Puel Jean-Luc; Kress Michaela; Baron Anne; Diochot Sylvie; Lazdunski Michel; Waldmann Rainer
Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing.
The Journal of physiology 2004;558(Pt 2):659-69.
2004: Patel Amanda J; Lazdunski Michel
The 2P-domain K+ channels: role in apoptosis and tumorigenesis.
Pflügers Archiv : European journal of physiology 2004;448(3):261-73.
2004: Chagot Benjamin; Escoubas Pierre; Villegas Elba; Bernard Cédric; Ferrat Gilles; Corzo Gerardo; Lazdunski Michel; Darbon Hervé
Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus.
Protein science : a publication of the Protein Society 2004;13(5):1197-208.
2004: Deval Emmanuel; Salinas Miguel; Baron Anne; Lingueglia Eric; Lazdunski Michel
ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1.
The Journal of biological chemistry 2004;279(19):19531-9.
2004: Diochot Sylvie; Baron Anne; Rash Lachlan D; Deval Emmanuel; Escoubas Pierre; Scarzello Sabine; Salinas Miguel; Lazdunski Michel
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons.
The EMBO journal 2004;23(7):1516-25.
2003: Mamet Julien; Lazdunski Michel; Voilley Nicolas
How nerve growth factor drives physiological and inflammatory expressions of acid-sensing ion channel 3 in sensory neurons.
The Journal of biological chemistry 2003;278(49):48907-13.
2003: Chemin Jean; Girard Christophe; Duprat Fabrice; Lesage Florian; Romey Georges; Lazdunski Michel
Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels.
The EMBO journal 2003;22(20):5403-11.
2003: Rouault Morgane; Bollinger James G; Lazdunski Michel; Gelb Michael H; Lambeau Gérard
Novel mammalian group XII secreted phospholipase A2 lacking enzymatic activity.
Biochemistry 2003;42(39):11494-503.
2003: Lang-Lazdunski Loïc; Blondeau Nicolas; Jarretou Gisèle; Lazdunski Michel; Heurteaux Catherine
Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2003;38(3):564-75.
2003: Lauritzen Inger; Zanzouri Marc; Honoré Eric; Duprat Fabrice; Ehrengruber Markus U; Lazdunski Michel; Patel Amanda J
K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels.
The Journal of biological chemistry 2003;278(34):32068-76.
2003: Escoubas Pierre; Bernard Cédric; Lambeau Gérard; Lazdunski Michel; Darbon Hervé
Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels.
Protein science : a publication of the Protein Society 2003;12(7):1332-43.
2003: Diochot Sylvie; Loret Erwann; Bruhn Thomas; Béress Lászlo; Lazdunski Michel
APETx1, a new toxin from the sea anemone Anthopleura elegantissima, blocks voltage-gated human ether-a-go-go-related gene potassium channels.
Molecular pharmacology 2003;64(1):59-69.
2003: Deval E; Baron A; Lingueglia E; Mazarguil H; Zajac J-M; Lazdunski M
Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability.
Neuropharmacology 2003;44(5):662-71.
2002: Mamet Julien; Baron Anne; Lazdunski Michel; Voilley Nicolas
Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(24):10662-70.
2002: Baron Anne; Deval Emmanuel; Salinas Miguel; Lingueglia Eric; Voilley Nicolas; Lazdunski Michel
Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1.
The Journal of biological chemistry 2002;277(52):50463-8.
2002: Singer Alan G; Ghomashchi Farideh; Le Calvez Catherine; Bollinger James; Bezzine Sofiane; Rouault Morgane; Sadilek Martin; Nguyen Eric; Lazdunski Michel; Lambeau Gerard; Gelb Michael H
Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2.
The Journal of biological chemistry 2002;277(50):48535-49.
2002: Girard Christophe; Tinel Norbert; Terrenoire Cécile; Romey Georges; Lazdunski Michel; Borsotto Marc
p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1.
The EMBO journal 2002;21(17):4439-48.
2002: Blondeau Nicolas; Lauritzen Inger; Widmann Catherine; Lazdunski Michel; Heurteaux Catherine
A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(7):821-34.
2002: Escoubas Pierre; Diochot Sylvie; Célérier Marie-Louise; Nakajima Terumi; Lazdunski Michel
Novel tarantula toxins for subtypes of voltage-dependent potassium channels in the Kv2 and Kv4 subfamilies.
Molecular pharmacology 2002;62(1):48-57.
2002: Honoré Eric; Maingret François; Lazdunski Michel; Patel Amanda Jane
An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.
The EMBO journal 2002;21(12):2968-76.
2002: Anzai Naohiko; Deval Emmanuel; Schaefer Lionel; Friend Valerie; Lazdunski Michel; Lingueglia Eric
The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons.
The Journal of biological chemistry 2002;277(19):16655-61.
2002: Maingret François; Honoré Eric; Lazdunski Michel; Patel Amanda Jane
Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel.
Biochemical and biophysical research communications 2002;292(2):339-46.
2002: Baron Anne; Waldmann Rainer; Lazdunski Michel
ASIC-like, proton-activated currents in rat hippocampal neurons.
The Journal of physiology 2002;539(Pt 2):485-94.
2002: Blondeau N; Widmann C; Lazdunski M; Heurteaux C
Polyunsaturated fatty acids induce ischemic and epileptic tolerance.
Neuroscience 2002;109(2):231-41.
2001: Voilley N; de Weille J; Mamet J; Lazdunski M
Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(20):8026-33.
2001: Baron A; Schaefer L; Lingueglia E; Champigny G; Lazdunski M
Zn2+ and H+ are coactivators of acid-sensing ion channels.
The Journal of biological chemistry 2001;276(38):35361-7.
2001: Terrenoire C; Lauritzen I; Lesage F; Romey G; Lazdunski M
A TREK-1-like potassium channel in atrial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics.
Circulation research 2001;89(4):336-42.
2001: Patel A J; Lazdunski M; Honoré E
Lipid and mechano-gated 2P domain K(+) channels.
Current opinion in cell biology 2001;13(4):422-8.
2001: Blondeau N; Widmann C; Lazdunski M; Heurteaux C
Activation of the nuclear factor-kappaB is a key event in brain tolerance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(13):4668-77.
2001: Girard C; Duprat F; Terrenoire C; Tinel N; Fosset M; Romey G; Lazdunski M; Lesage F
Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels.
Biochemical and biophysical research communications 2001;282(1):249-56.
2001: Maingret F; Patel A J; Lazdunski M; Honoré E
The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.
The EMBO journal 2001;20(1-2):47-54.
2001: Ettaiche M; Heurteaux C; Blondeau N; Borsotto M; Tinel N; Lazdunski M
ATP-sensitive potassium channels (K(ATP)) in retina: a key role for delayed ischemic tolerance.
Brain research 2001;890(1):118-29.
2000: Valentin E; Singer A G; Ghomashchi F; Lazdunski M; Gelb M H; Lambeau G
Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).
Biochemical and biophysical research communications 2000;279(1):223-8.
2000: Tinel N; Diochot S; Borsotto M; Lazdunski M; Barhanin J
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel.
The EMBO journal 2000;19(23):6326-30.
2000: Gelb M H; Valentin E; Ghomashchi F; Lazdunski M; Lambeau G
Cloning and recombinant expression of a structurally novel human secreted phospholipase A2.
The Journal of biological chemistry 2000;275(51):39823-6.
2000: Drici M D; Diochot S; Terrenoire C; Romey G; Lazdunski M
The bee venom peptide tertiapin underlines the role of I(KACh) in acetylcholine-induced atrioventricular blocks.
British journal of pharmacology 2000;131(3):569-77.
2000: Tinel N; Diochot S; Lauritzen I; Barhanin J; Lazdunski M; Borsotto M
M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit.
FEBS letters 2000;480(2-3):137-41.
2000: Patel A J; Maingret F; Magnone V; Fosset M; Lazdunski M; Honoré E
TWIK-2, an inactivating 2P domain K+ channel.
The Journal of biological chemistry 2000;275(37):28722-30.
2000: Lesage F; Terrenoire C; Romey G; Lazdunski M
Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors.
The Journal of biological chemistry 2000;275(37):28398-405.
2000: Lang-Lazdunski L; Heurteaux C; Mignon A; Mantz J; Widmann C; Desmonts J; Lazdunski M
Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2000;18(2):174-81.
2000: Escoubas P; De Weille J R; Lecoq A; Diochot S; Waldmann R; Champigny G; Moinier D; Ménez A; Lazdunski M
Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.
The Journal of biological chemistry 2000;275(33):25116-21.
2000: Lang-Lazdunski L; Heurteaux C; Dupont H; Widmann C; Lazdunski M
Prevention of ischemic spinal cord injury: comparative effects of magnesium sulfate and riluzole.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2000;32(1):179-89.
2000: Maingret F; Lauritzen I; Patel A J; Heurteaux C; Reyes R; Lesage F; Lazdunski M; Honoré E
TREK-1 is a heat-activated background K(+) channel.
The EMBO journal 2000;19(11):2483-91.
2000: Coscoy S; de Weille J; Lingueglia E; Fukuda N; Matthay M; Lazdunski M; Barbry P
[Amiloride-sensitive sodium channel in the nephron and its activation by vasopressin]
Annales d'endocrinologie 2000;61(2):145-6.
2000: Duprat F; Lesage F; Patel A J; Fink M; Romey G; Lazdunski M
The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK.
Molecular pharmacology 2000;57(5):906-12.
2000: Lauritzen I; Blondeau N; Heurteaux C; Widmann C; Romey G; Lazdunski M
Polyunsaturated fatty acids are potent neuroprotectors.
The EMBO journal 2000;19(8):1784-93.
2000: Schaefer L; Sakai H; Mattei M; Lazdunski M; Lingueglia E
Molecular cloning, functional expression and chromosomal localization of an amiloride-sensitive Na(+) channel from human small intestine.
FEBS letters 2000;471(2-3):205-10.
2000: Lesage F; Maingret F; Lazdunski M
Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel.
FEBS letters 2000;471(2-3):137-40.
2000: Maingret F; Patel A J; Lesage F; Lazdunski M; Honoré E
Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK.
The Journal of biological chemistry 2000;275(14):10128-33.
2000: Valentin E; Ghomashchi F; Gelb M H; Lazdunski M; Lambeau G
Novel human secreted phospholipase A(2) with homology to the group III bee venom enzyme.
The Journal of biological chemistry 2000;275(11):7492-6.
2000: Blondeau N; Plamondon H; Richelme C; Heurteaux C; Lazdunski M
K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection.
Neuroscience 2000;100(3):465-74.
2000: Reyes R; Lauritzen I; Lesage F; Ettaiche M; Fosset M; Lazdunski M
Immunolocalization of the arachidonic acid and mechanosensitive baseline traak potassium channel in the nervous system.
Neuroscience 2000;95(3):893-901.
1999: Plamondon H; Blondeau N; Heurteaux C; Lazdunski M
Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(12):1296-308.
1999: Schweitz H; Pacaud P; Diochot S; Moinier D; Lazdunski M
MIT(1), a black mamba toxin with a new and highly potent activity on intestinal contraction.
FEBS letters 1999;461(3):183-8.
1999: Valentin E; Ghomashchi F; Gelb M H; Lazdunski M; Lambeau G
On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.
The Journal of biological chemistry 1999;274(44):31195-202.
1999: Fenard D; Lambeau G; Valentin E; Lefebvre J C; Lazdunski M; Doglio A
Secreted phospholipases A(2), a new class of HIV inhibitors that block virus entry into host cells.
The Journal of clinical investigation 1999;104(5):611-8.
1999: Maingret F; Patel A J; Lesage F; Lazdunski M; Honoré E
Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel.
The Journal of biological chemistry 1999;274(38):26691-6.
1999: Sakai H; Lingueglia E; Champigny G; Mattei M G; Lazdunski M
Cloning and functional expression of a novel degenerin-like Na+ channel gene in mammals.
The Journal of physiology 1999;519 Pt 2():323-33.
1999: Valentin E; Koduri R S; Scimeca J C; Carle G; Gelb M H; Lazdunski M; Lambeau G
Cloning and recombinant expression of a novel mouse-secreted phospholipase A2.
The Journal of biological chemistry 1999;274(27):19152-60.
1999: Patel A J; Honoré E; Lesage F; Fink M; Romey G; Lazdunski M
Inhalational anesthetics activate two-pore-domain background K+ channels.
Nature neuroscience 1999;2(5):422-6.
1999: Lang-Lazdunski L; Heurteaux C; Vaillant N; Widmann C; Lazdunski M
Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping.
The Journal of thoracic and cardiovascular surgery 1999;117(5):881-9.
1999: Patel A J; Lazdunski M; Honoré E
Kv2.1/Kv9.3, an ATP-dependent delayed-rectifier K+ channel in pulmonary artery myocytes.
Annals of the New York Academy of Sciences 1999;868():438-41.
1999: Waldmann R; Champigny G; Lingueglia E; De Weille J R; Heurteaux C; Lazdunski M
H(+)-gated cation channels.
Annals of the New York Academy of Sciences 1999;868():67-76.
1999: Salinas M; Reyes R; Lesage F; Fosset M; Heurteaux C; Romey G; Lazdunski M
Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure.
The Journal of biological chemistry 1999;274(17):11751-60.
1999: Coscoy S; de Weille J R; Lingueglia E; Lazdunski M
The pre-transmembrane 1 domain of acid-sensing ion channels participates in the ion pore.
The Journal of biological chemistry 1999;274(15):10129-32.
1999: Ettaiche M; Fillacier K; Widmann C; Heurteaux C; Lazdunski M
Riluzole improves functional recovery after ischemia in the rat retina.
Investigative ophthalmology & visual science 1999;40(3):729-36.
1999: Cupillard L; Mulherkar R; Gomez N; Kadam S; Valentin E; Lazdunski M; Lambeau G
Both group IB and group IIA secreted phospholipases A2 are natural ligands of the mouse 180-kDa M-type receptor.
The Journal of biological chemistry 1999;274(11):7043-51.
1999: Diochot S; Drici M D; Moinier D; Fink M; Lazdunski M
Effects of phrixotoxins on the Kv4 family of potassium channels and implications for the role of Ito1 in cardiac electrogenesis.
British journal of pharmacology 1999;126(1):251-63.
1999: Maingret F; Fosset M; Lesage F; Lazdunski M; Honoré E
TRAAK is a mammalian neuronal mechano-gated K+ channel.
The Journal of biological chemistry 1999;274(3):1381-7.
1998: Tinel N; Lauritzen I; Chouabe C; Lazdunski M; Borsotto M
The KCNQ2 potassium channel: splice variants, functional and developmental expression. Brain localization and comparison with KCNQ3.
FEBS letters 1998;438(3):171-6.
1998: Reyes R; Duprat F; Lesage F; Fink M; Salinas M; Farman N; Lazdunski M
Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney.
The Journal of biological chemistry 1998;273(47):30863-9.
1998: Chouabe C; Drici M D; Romey G; Barhanin J; Lazdunski M
HERG and KvLQT1/IsK, the cardiac K+ channels involved in long QT syndromes, are targets for calcium channel blockers.
Molecular pharmacology 1998;54(4):695-703.
1998: de Weille J R; Bassilana F; Lazdunski M; Waldmann R
Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel.
FEBS letters 1998;433(3):257-60.
1998: Lesage F; Lazdunski M
Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23.
Genomics 1998;51(3):478-9.
1998: Patel A J; Honoré E; Maingret F; Lesage F; Fink M; Duprat F; Lazdunski M
A mammalian two pore domain mechano-gated S-like K+ channel.
The EMBO journal 1998;17(15):4283-90.
1998: Persu A; Barbry P; Bassilana F; Houot A M; Mengual R; Lazdunski M; Corvol P; Jeunemaitre X
Genetic analysis of the beta subunit of the epithelial Na+ channel in essential hypertension.
Hypertension 1998;32(1):129-37.
1998: Drici M D; Arrighi I; Chouabe C; Mann J R; Lazdunski M; Romey G; Barhanin J
Involvement of IsK-associated K+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome.
Circulation research 1998;83(1):95-102.
1998: Waldmann R; Lazdunski M
H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels.
Current opinion in neurobiology 1998;8(3):418-24.
1998: Fink M; Lesage F; Duprat F; Heurteaux C; Reyes R; Fosset M; Lazdunski M
A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids.
The EMBO journal 1998;17(12):3297-308.
1998: Champigny G; Voilley N; Waldmann R; Lazdunski M
Mutations causing neurodegeneration in Caenorhabditis elegans drastically alter the pH sensitivity and inactivation of the mammalian H+-gated Na+ channel MDEG1.
The Journal of biological chemistry 1998;273(25):15418-22.
1998: Darboux I; Lingueglia E; Pauron D; Barbry P; Lazdunski M
A new member of the amiloride-sensitive sodium channel family in Drosophila melanogaster peripheral nervous system.
Biochemical and biophysical research communications 1998;246(1):210-6.
1998: Patel A J; Lauritzen I; Lazdunski M; Honoré E
Disruption of mitochondrial respiration inhibits volume-regulated anion channels and provokes neuronal cell swelling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(9):3117-23.
1998: Darboux I; Lingueglia E; Champigny G; Coscoy S; Barbry P; Lazdunski M
dGNaC1, a gonad-specific amiloride-sensitive Na+ channel.
The Journal of biological chemistry 1998;273(16):9424-9.
1998: Coscoy S; Lingueglia E; Lazdunski M; Barbry P
The Phe-Met-Arg-Phe-amide-activated sodium channel is a tetramer.
The Journal of biological chemistry 1998;273(14):8317-22.
1998: Diochot S; Schweitz H; Béress L; Lazdunski M
Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4.
The Journal of biological chemistry 1998;273(12):6744-9.
1997: Schmid-Antomarchi H; Schmid-Alliana A; Romey G; Ventura M A; Breittmayer V; Millet M A; Husson H; Moghrabi B; Lazdunski M; Rossi B
Extracellular ATP and UTP control the generation of reactive oxygen intermediates in human macrophages through the opening of a charybdotoxin-sensitive Ca2+-dependent K+ channel.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):6209-15.
1997: Lingueglia E; de Weille J R; Bassilana F; Heurteaux C; Sakai H; Waldmann R; Lazdunski M
A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells.
The Journal of biological chemistry 1997;272(47):29778-83.
1997: Patel A J; Lazdunski M; Honoré E
Kv2.1/Kv9.3, a novel ATP-dependent delayed-rectifier K+ channel in oxygen-sensitive pulmonary artery myocytes.
The EMBO journal 1997;16(22):6615-25.
1997: Bassilana F; Champigny G; Waldmann R; de Weille J R; Heurteaux C; Lazdunski M
The acid-sensitive ionic channel subunit ASIC and the mammalian degenerin MDEG form a heteromultimeric H+-gated Na+ channel with novel properties.
The Journal of biological chemistry 1997;272(46):28819-22.
1997: Voilley N; Galibert A; Bassilana F; Renard S; Lingueglia E; Coscoy S; Champigny G; Hofman P; Lazdunski M; Barbry P
The amiloride-sensitive Na+ channel: from primary structure to function.
Comparative biochemistry and physiology. Part A, Physiology 1997;118(2):193-200.
1997: Jeunemaitre X; Bassilana F; Persu A; Dumont C; Champigny G; Lazdunski M; Corvol P; Barbry P
Genotype-phenotype analysis of a newly discovered family with Liddle's syndrome.
Journal of hypertension 1997;15(10):1091-100.
1997: Lauritzen I; De Weille J R; Lazdunski M
The potassium channel opener (-)-cromakalim prevents glutamate-induced cell death in hippocampal neurons.
Journal of neurochemistry 1997;69(4):1570-9.
1997: Chouabe C; Neyroud N; Guicheney P; Lazdunski M; Romey G; Barhanin J
Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias.
The EMBO journal 1997;16(17):5472-9.
1997: Duprat F; Lesage F; Fink M; Reyes R; Heurteaux C; Lazdunski M
TASK, a human background K+ channel to sense external pH variations near physiological pH.
The EMBO journal 1997;16(17):5464-71.
1997: Salinas M; Duprat F; Heurteaux C; Hugnot J P; Lazdunski M
New modulatory alpha subunits for mammalian Shab K+ channels.
The Journal of biological chemistry 1997;272(39):24371-9.
1997: Murer G; Adelbrecht C; Lauritzen I; Lesage F; Lazdunski M; Agid Y; Raisman-Vozari R
An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain.
Neuroscience 1997;80(2):345-57.
1997: Waldmann R; Bassilana F; de Weille J; Champigny G; Heurteaux C; Lazdunski M
Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons.
The Journal of biological chemistry 1997;272(34):20975-8.
1997: Romey G; Attali B; Chouabe C; Abitbol I; Guillemare E; Barhanin J; Lazdunski M
Molecular mechanism and functional significance of the MinK control of the KvLQT1 channel activity.
The Journal of biological chemistry 1997;272(27):16713-6.
1997: Cupillard L; Koumanov K; Mattéi M G; Lazdunski M; Lambeau G
Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2.
The Journal of biological chemistry 1997;272(25):15745-52.
1997: Lauritzen I; De Weille J; Adelbrecht C; Lesage F; Murer G; Raisman-Vozari R; Lazdunski M
Comparative expression of the inward rectifier K+ channel GIRK2 in the cerebellum of normal and weaver mutant mice.
Brain research 1997;753(1):8-17.
1997: Salinas M; de Weille J; Guillemare E; Lazdunski M; Hugnot J P
Modes of regulation of shab K+ channel activity by the Kv8.1 subunit.
The Journal of biological chemistry 1997;272(13):8774-80.
1997: Waldmann R; Champigny G; Bassilana F; Heurteaux C; Lazdunski M
A proton-gated cation channel involved in acid-sensing.
Nature 1997;386(6621):173-7.
1997: Nicolas J P; Lin Y; Lambeau G; Ghomashchi F; Lazdunski M; Gelb M H
Localization of structural elements of bee venom phospholipase A2 involved in N-type receptor binding and neurotoxicity.
The Journal of biological chemistry 1997;272(11):7173-81.
1997: Lesage F; Lauritzen I; Duprat F; Reyes R; Fink M; Heurteaux C; Lazdunski M
The structure, function and distribution of the mouse TWIK-1 K+ channel.
FEBS letters 1997;402(1):28-32.
1996: Fink M; Duprat F; Lesage F; Reyes R; Romey G; Heurteaux C; Lazdunski M
Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel.
The EMBO journal 1996;15(24):6854-62.
1996: Lesage F; Reyes R; Fink M; Duprat F; Guillemare E; Lazdunski M
Dimerization of TWIK-1 K+ channel subunits via a disulfide bridge.
The EMBO journal 1996;15(23):6400-7.
1996: Barhanin J; Lesage F; Guillemare E; Fink M; Lazdunski M; Romey G
K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current.
Nature 1996;384(6604):78-80.
1996: Waldmann R; Voilley N; Mattéï M G; Lazdunski M
The human degenerin MDEG, an amiloride-sensitive neuronal cation channel, is localized on chromosome 17q11.2-17q12 close to the microsatellite D17S798.
Genomics 1996;37(2):269-70.
1996: Fink M; Duprat F; Lesage F; Heurteaux C; Romey G; Barhanin J; Lazdunski M
A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression.
The Journal of biological chemistry 1996;271(42):26341-8.
1996: Lazdunski M
Ion channel effects of antidiabetic sulfonylureas.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(9):488-95.
1996: Hugnot J P; Salinas M; Lesage F; Guillemare E; de Weille J; Heurteaux C; Mattéi M G; Lazdunski M
Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels.
The EMBO journal 1996;15(13):3322-31.
1996: Waldmann R; Bassilana F; Voilley N; Lazdunski M; Mattéi M
Assignment of the human amiloride-sensitive Na+ channel delta isoform to chromosome 1p36.3-p36.2.
Genomics 1996;34(2):262-3.
1996: Lingueglia E; Voilley N; Lazdunski M; Barbry P
Molecular biology of the amiloride-sensitive epithelial Na+ channel.
Experimental physiology 1996;81(3):483-92.
1996: Lesage F; Mattéi M; Fink M; Barhanin J; Lazdunski M
Assignment of the human weak inward rectifier K+ channel TWIK-1 gene to chromosome 1q42-q43.
Genomics 1996;34(1):153-5.
1996: Waldmann R; Champigny G; Voilley N; Lauritzen I; Lazdunski M
The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans.
The Journal of biological chemistry 1996;271(18):10433-6.
1996: Lesage F; Guillemare E; Fink M; Duprat F; Lazdunski M; Romey G; Barhanin J
TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.
The EMBO journal 1996;15(5):1004-11.
1996: Lesage F; Guillemare E; Fink M; Duprat F; Lazdunski M; Romey G; Barhanin J
A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties.
The Journal of biological chemistry 1996;271(8):4183-7.
1996: Zvaritch E; Lambeau G; Lazdunski M
Endocytic properties of the M-type 180-kDa receptor for secretory phospholipases A2.
The Journal of biological chemistry 1996;271(1):250-7.
1996: Fink M; Duprat F; Heurteaux C; Lesage F; Romey G; Barhanin J; Lazdunski M
Dominant negative chimeras provide evidence for homo and heteromultimeric assembly of inward rectifier K+ channel proteins via their N-terminal end.
FEBS letters 1996;378(1):64-8.
1996: Lambeau G; Ancian P; Nicolas J P; Cupillard L; Zvaritch E; Lazdunski M
[A family of receptors for secretory phospholipases A2]
Comptes rendus des séances de la Société de biologie et de ses filiales 1996;190(4):425-35.
1995: Duprat F; Guillemare E; Romey G; Fink M; Lesage F; Lazdunski M; Honore E
Susceptibility of cloned K+ channels to reactive oxygen species.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11796-800.
1995: Lingueglia E; Champigny G; Lazdunski M; Barbry P
Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel.
Nature 1995;378(6558):730-3.
1995: Nicolas J P; Lambeau G; Lazdunski M
Identification of the binding domain for secretory phospholipases A2 on their M-type 180-kDa membrane receptor.
The Journal of biological chemistry 1995;270(48):28869-73.
1995: Lesage F; Guillemare E; Fink M; Duprat F; Heurteaux C; Fosset M; Romey G; Barhanin J; Lazdunski M
Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.
The Journal of biological chemistry 1995;270(48):28660-7.
1995: Fosset M; Allard B; Lazdunski M
Coexistence of two classes of glibenclamide-inhibitable ATP-regulated K+ channels in avian skeletal muscle.
Pflügers Archiv : European journal of physiology 1995;431(1):117-24.
1995: Waldmann R; Champigny G; Bassilana F; Voilley N; Lazdunski M
Molecular cloning and functional expression of a novel amiloride-sensitive Na+ channel.
The Journal of biological chemistry 1995;270(46):27411-4.
1995: Lesage F; Fink M; Barhanin J; Lazdunski M; Mattéi M G
Assignment of human G-protein-coupled inward rectifier K+ channel homolog GIRK3 gene to chromosome 1q21-q23.
Genomics 1995;29(3):808-9.
1995: Schweitz H; Bruhn T; Guillemare E; Moinier D; Lancelin J M; Béress L; Lazdunski M
Kalicludines and kaliseptine. Two different classes of sea anemone toxins for voltage sensitive K+ channels.
The Journal of biological chemistry 1995;270(42):25121-6.
1995: Ancian P; Lambeau G; Lazdunski M
Multifunctional activity of the extracellular domain of the M-type (180 kDa) membrane receptor for secretory phospholipases A2.
Biochemistry 1995;34(40):13146-51.
1995: Voilley N; Bassilana F; Mignon C; Merscher S; Mattéi M G; Carle G F; Lazdunski M; Barbry P
Cloning, chromosomal localization, and physical linkage of the beta and gamma subunits (SCNN1B and SCNN1G) of the human epithelial amiloride-sensitive sodium channel.
Genomics 1995;28(3):560-5.
1995: Duprat F; Lesage F; Guillemare E; Fink M; Hugnot J P; Bigay J; Lazdunski M; Romey G; Barhanin J
Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers.
Biochemical and biophysical research communications 1995;212(2):657-63.
1995: Renard S; Voilley N; Bassilana F; Lazdunski M; Barbry P
Localization and regulation by steroids of the alpha, beta and gamma subunits of the amiloride-sensitive Na+ channel in colon, lung and kidney.
Pflügers Archiv : European journal of physiology 1995;430(3):299-307.
1995: Champigny G; Imler J L; Puchelle E; Dalemans W; Gribkoff V; Hinnrasky J; Dott K; Barbry P; Pavirani A; Lazdunski M
A change in gating mode leading to increased intrinsic Cl- channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease.
The EMBO journal 1995;14(11):2417-23.
1995: Heurteaux C; Lauritzen I; Widmann C; Lazdunski M
Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4666-70.
1995: Waldmann R; Champigny G; Lazdunski M
Functional degenerin-containing chimeras identify residues essential for amiloride-sensitive Na+ channel function.
The Journal of biological chemistry 1995;270(20):11735-7.
1995: Ancian P; Lambeau G; Mattéi M G; Lazdunski M
The human 180-kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization.
The Journal of biological chemistry 1995;270(15):8963-70.
1995: Lambeau G; Ancian P; Nicolas J P; Beiboer S H; Moinier D; Verheij H; Lazdunski M
Structural elements of secretory phospholipases A2 involved in the binding to M-type receptors.
The Journal of biological chemistry 1995;270(10):5534-40.
1995: Honoré E; Lazdunski M
Biophysical, pharmacological and developmental properties of ATP-sensitive K+ channels in cultured myotomal muscle cells from Xenopus embryos.
Pflügers Archiv : European journal of physiology 1995;429(5):607-16.
1995: Guillemare E; Lazdunski M; Honoré E
Glibenclamide opens ATP-sensitive potassium channels in Xenopus oocyte follicular cells during metabolic stress.
Molecular pharmacology 1995;47(3):588-94.
1994: Romey G; Lazdunski M
Effects of a new class of calcium antagonists, SR33557 (fantofarone) and SR33805, on neuronal voltage-activated Ca++ channels.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1348-52.
1994: Van Renterghem C; Lazdunski M
Identification of the Ca2+ current activated by vasoconstrictors in vascular smooth muscle cells.
Pflügers Archiv : European journal of physiology 1994;429(1):1-6.
1994: Lesage F; Duprat F; Fink M; Guillemare E; Coppola T; Lazdunski M; Hugnot J P
Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain.
FEBS letters 1994;353(1):37-42.
1994: Heurteaux C; Lauritzen I; Widmann C; Lazdunski M
Glutamate-induced overexpression of NMDA receptor messenger RNAs and protein triggered by activation of AMPA/kainate receptors in rat hippocampus following forebrain ischemia.
Brain research 1994;659(1-2):67-74.
1994: Guillemare E; Lazdunski M; Honoré E
CGRP-induced activation of KATP channels in follicular Xenopus oocytes.
Pflügers Archiv : European journal of physiology 1994;428(5-6):604-9.
1994: Lesage F; Hugnot J P; Amri E Z; Grimaldi P; Barhanin J; Lazdunski M
Expression cloning in K+ transport defective yeast and distribution of HBP1, a new putative HMG transcriptional regulator.
Nucleic acids research 1994;22(18):3685-8.
1994: Romey G; Bois P; Lazdunski M
Effects of two chemically related new Ca2+ channel antagonists, SR33557 (fantofarone) and SR33805, on the L-type cardiac channel.
European journal of pharmacology 1994;263(1-2):101-5.
1994: Guillemare E; Honore E; De Weille J; Fosset M; Lazdunski M; Meisheri K
Functional receptors in Xenopus oocytes for U-37883A, a novel ATP-sensitive K+ channel blocker: comparison with rat insulinoma cells.
Molecular pharmacology 1994;46(1):139-45.
1994: Lauritzen I; Heurteaux C; Lazdunski M
Expression of group II phospholipase A2 in rat brain after severe forebrain ischemia and in endotoxic shock.
Brain research 1994;651(1-2):353-6.
1994: Honoré E; Guillemare E; Lesage F; Barhanin J; Lazdunski M
Injection of a K+ channel (Kv1.3) cRNA in fertilized eggs leads to functional expression in cultured myotomal muscle cells from Xenopus embryos.
FEBS letters 1994;348(3):259-62.
1994: Lingueglia E; Renard S; Waldmann R; Voilley N; Champigny G; Plass H; Lazdunski M; Barbry P
Different homologous subunits of the amiloride-sensitive Na+ channel are differently regulated by aldosterone.
The Journal of biological chemistry 1994;269(19):13736-9.
1994: Champigny G; Voilley N; Lingueglia E; Friend V; Barbry P; Lazdunski M
Regulation of expression of the lung amiloride-sensitive Na+ channel by steroid hormones.
The EMBO journal 1994;13(9):2177-81.
1994: Chassande O; Renard S; Barbry P; Lazdunski M
The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter.
The Journal of biological chemistry 1994;269(20):14484-9.
1994: Lazdunski M; Allard B; Bernardi H; De Weille J; Fosset M; Heurteaux C; Honoré E
ATP-sensitive K+ channels.
Renal physiology and biochemistry 1994;17(3-4):118-20.
1994: Renard S; Lingueglia E; Voilley N; Lazdunski M; Barbry P
Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel.
The Journal of biological chemistry 1994;269(17):12981-6.
1994: Novotny W F; Chassande O; Baker M; Lazdunski M; Barbry P
Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues.
The Journal of biological chemistry 1994;269(13):9921-5.
1994: Honoré E; Barhanin J; Attali B; Lesage F; Lazdunski M
External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1937-41.
1994: Schweitz H; Heurteaux C; Bois P; Moinier D; Romey G; Lazdunski M
Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):878-82.
1994: Coppola T; Waldmann R; Borsotto M; Heurteaux C; Romey G; Mattéi M G; Lazdunski M
Molecular cloning of a murine N-type calcium channel alpha 1 subunit. Evidence for isoforms, brain distribution, and chromosomal localization.
FEBS letters 1994;338(1):1-5.
1994: Lambeau G; Ancian P; Barhanin J; Lazdunski M
Cloning and expression of a membrane receptor for secretory phospholipases A2.
The Journal of biological chemistry 1994;269(3):1575-8.
1994: Voilley N; Lingueglia E; Champigny G; Mattéi M G; Waldmann R; Lazdunski M; Barbry P
The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):247-51.
1994: Lazdunski M
ATP-sensitive potassium channels: an overview.
Journal of cardiovascular pharmacology 1994;24 Suppl 4():S1-5.
1993: Attali B; Lesage F; Ziliani P; Guillemare E; Honoré E; Waldmann R; Hugnot J P; Mattéi M G; Lazdunski M; Barhanin J
Multiple mRNA isoforms encoding the mouse cardiac Kv1-5 delayed rectifier K+ channel.
The Journal of biological chemistry 1993;268(32):24283-9.
1993: Heurteaux C; Bertaina V; Widmann C; Lazdunski M
K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9431-5.
1993: Attali B; Guillemare E; Lesage F; Honoré E; Romey G; Lazdunski M; Barhanin J
The protein IsK is a dual activator of K+ and Cl- channels.
Nature 1993;365(6449):850-2.
1993: Van Renterghem C; Lazdunski M
Endothelin and vasopressin activate low conductance chloride channels in aortic smooth muscle cells.
Pflügers Archiv : European journal of physiology 1993;425(1-2):156-63.
1993: Lingueglia E; Renard S; Voilley N; Waldmann R; Chassande O; Lazdunski M; Barbry P
Molecular cloning and functional expression of different molecular forms of rat amiloride-binding proteins.
European journal of biochemistry / FEBS 1993;216(2):679-87.
1993: Honoré E; Lazdunski M
Single-channel properties and regulation of pinacidil/glibenclamide-sensitive K+ channels in follicular cells from Xenopus oocyte.
Pflügers Archiv : European journal of physiology 1993;424(2):113-21.
1993: Allard B; Lazdunski M
Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells.
European journal of pharmacology 1993;236(3):419-26.
1993: Heurteaux C; Messier C; Destrade C; Lazdunski M
Memory processing and apamin induce immediate early gene expression in mouse brain.
Brain research. Molecular brain research 1993;18(1-2):17-22.
1993: Bernardi H; De Weille J R; Epelbaum J; Mourre C; Amoroso S; Slama A; Fosset M; Lazdunski M
ATP-modulated K+ channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1340-4.
1993: Lingueglia E; Voilley N; Waldmann R; Lazdunski M; Barbry P
Expression cloning of an epithelial amiloride-sensitive Na+ channel. A new channel type with homologies to Caenorhabditis elegans degenerins.
FEBS letters 1993;318(1):95-9.
1993: Lesage F; Attali B; Lakey J; Honoré E; Romey G; Faurobert E; Lazdunski M; Barhanin J
Are Xenopus oocytes unique in displaying functional IsK channel heterologous expression?
Receptors & channels 1993;1(2):143-52.
1992: Auguste P; Hugues M; Borsotto M; Thibault J; Romey G; Coppola T; Lazdunski M
Characterization and partial purification from pheochromocytoma cells of an endogenous equivalent of scyllatoxin, a scorpion toxin which blocks small conductance Ca(2+)-activated K+ channels.
Brain research 1992;599(2):230-6.
1992: Guillemare E; Honoré E; Pradier L; Lesage F; Schweitz H; Attali B; Barhanin J; Lazdunski M
Effects of the level of mRNA expression on biophysical properties, sensitivity to neurotoxins, and regulation of the brain delayed-rectifier K+ channels Kv1.2.
Biochemistry 1992;31(49):12463-8.
1992: Allard B; Lazdunski M
Nucleotide diphosphates activate the ATP-sensitive potassium channel in mouse skeletal muscle.
Pflügers Archiv : European journal of physiology 1992;422(2):185-92.
1992: Lesage F; Attali B; Lazdunski M; Barhanin J
Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.
FEBS letters 1992;310(2):162-6.
1992: Fosset M; Epelbaum J; Lazdunski M
Antidiabetic sulfonylureas antagonize somatostatin inhibition of prolactin secretion in vitro.
European journal of pharmacology 1992;220(2-3):273-4.
1992: De Weille J R; Fosset M; Epelbaum J; Lazdunski M
Effectors of ATP-sensitive K+ channels inhibit the regulatory effects of somatostatin and GH-releasing factor on growth hormone secretion.
Biochemical and biophysical research communications 1992;187(2):1007-14.
1992: Bernardi H; Fosset M; Lazdunski M
ATP/ADP binding sites are present in the sulfonylurea binding protein associated with brain ATP-sensitive K+ channels.
Biochemistry 1992;31(27):6328-32.
1992: Honoré E; Attali B; Romey G; Lesage F; Barhanin J; Lazdunski M
Different types of K+ channel current are generated by different levels of a single mRNA.
The EMBO journal 1992;11(7):2465-71.
1992: Schweitz H; Vigne P; Moinier D; Frelin C; Lazdunski M
A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps).
The Journal of biological chemistry 1992;267(20):13928-32.
1992: Szewczyk A; De Weille J R; Lazdunski M
TMB-8 (8-(N,N-diethylamino) octyl-3,4,5-trimethoxybenzoate) inhibits the ATP-sensitive K+ channel.
European journal of pharmacology 1992;226(2):175-7.
1992: Attali B; Honoré E; Lesage F; Lazdunski M; Barhanin J
Regulation of a major cloned voltage-gated K+ channel from human T lymphocytes.
FEBS letters 1992;303(2-3):229-32.
1992: Wibrand F; Honoré E; Lazdunski M
Opening of glibenclamide-sensitive K+ channels in follicular cells promotes Xenopus oocyte maturation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5133-7.
1992: Szewczyk A; De Weille J R; Lazdunski M
8-Methoxypsoralen blocks ATP-sensitive potassium channels and stimulates insulin release.
European journal of pharmacology 1992;216(2):323-6.
1992: Müller M; Szewczyk A; De Weille J R; Lazdunski M
ATP-sensitive K+ channels in insulinoma cells are activated by nonesterified fatty acids.
Biochemistry 1992;31(19):4656-61.
1992: Honore E; Attali B; Lesage F; Barhanin J; Lazdunski M
Receptor-mediated regulation of IsK, a very slowly activating, voltage-dependent K+ channel in Xenopus oocytes.
Biochemical and biophysical research communications 1992;184(3):1135-41.
1992: Lesage F; Attali B; Lazdunski M; Barhanin J
ISK, a slowly activating voltage-sensitive K+ channel. Characterization of multiple cDNAs and gene organization in the mouse.
FEBS letters 1992;301(2):168-72.
1992: Van Renterghem C; Lazdunski M
A small-conductance charybdotoxin-sensitive, apamin-resistant Ca(2+)-activated K+ channel in aortic smooth muscle cells (A7r5 line and primary culture).
Pflügers Archiv : European journal of physiology 1992;420(5-6):417-23.
1992: Attali B; Romey G; Honoré E; Schmid-Alliana A; Mattéi M G; Lesage F; Ricard P; Barhanin J; Lazdunski M
Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.
The Journal of biological chemistry 1992;267(12):8650-7.
1992: de Weille J R; Müller M; Lazdunski M
Activation and inhibition of ATP-sensitive K+ channels by fluorescein derivatives.
The Journal of biological chemistry 1992;267(7):4557-63.
1992: Auguste P; Hugues M; Mourre C; Moinier D; Tartar A; Lazdunski M
Scyllatoxin, a blocker of Ca(2+)-activated K+ channels: structure-function relationships and brain localization of the binding sites.
Biochemistry 1992;31(3):648-54.
1992: Lazdunski M; Bernardi H; de Weille J R; Mourre C; Fosset M
Agonists and antagonists of ATP-sensitive potassium channels.
Advances in nephrology from the Necker Hospital 1992;21():195-202.
1991: Bois P; Romey G; Lazdunski M
Indolizinsulphones. A class of blockers with dual but discriminative effects on L-type Ca2+ channel activity and excitation-contraction coupling in skeletal muscle.
Pflügers Archiv : European journal of physiology 1991;419(6):651-6.
1991: Lambeau G; Barhanin J; Lazdunski M
Identification of different receptor types for toxic phospholipases A2 in rabbit skeletal muscle.
FEBS letters 1991;293(1-2):29-33.
1991: Van Renterghem C; Lazdunski M
A new non-voltage-dependent, epithelial-like Na+ channel in vascular smooth muscle cells.
Pflügers Archiv : European journal of physiology 1991;419(3-4):401-8.
1991: Honoré E; Attali B; Romey G; Heurteaux C; Ricard P; Lesage F; Lazdunski M; Barhanin J
Cloning, expression, pharmacology and regulation of a delayed rectifier K+ channel in mouse heart.
The EMBO journal 1991;10(10):2805-11.
1991: Honoré E; Lazdunski M
Two different types of channels are targets for potassium channel openers in Xenopus oocytes.
FEBS letters 1991;287(1-2):75-9.
1991: Heurteaux C; Lazdunski M
MCD peptide and dendrotoxin I activate c-fos and c-jun expression by acting on two different types of K+ channels. A discrimination using the K+ channel opener lemakalim.
Brain research 1991;554(1-2):22-9.
1991: Honoré E; Lazdunski M
Hormone-regulated K+ channels in follicle-enclosed oocytes are activated by vasorelaxing K+ channel openers and blocked by antidiabetic sulfonylureas.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5438-42.
1991: Champigny G; Verrier B; Lazdunski M
A voltage, calcium, and ATP sensitive non selective cation channel in human colonic tumor cells.
Biochemical and biophysical research communications 1991;176(3):1196-203.
1991: Müller M; De Weille J R; Lazdunski M
Chlorpromazine and related phenothiazines inhibit the ATP-sensitive K+ channel.
European journal of pharmacology 1991;198(1):101-4.
1991: de Weille J R; Schweitz H; Maes P; Tartar A; Lazdunski M
Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2437-40.
1991: Mourre C; Widmann C; Lazdunski M
Specific hippocampal lesions indicate the presence of sulfonylurea binding sites associated to ATP-sensitive K+ channels both post-synaptically and on mossy fibers.
Brain research 1991;540(1-2):340-4.
1991: Häusser M A; de Weille J R; Lazdunski M
Activation by cromakalim of pre- and post-synaptic ATP-sensitive K+ channels in substantia nigra.
Biochemical and biophysical research communications 1991;174(2):909-14.
1991: Schaeffer P; Lazdunski M
K+ efflux pathways and neurotransmitter release associated to hippocampal ischemia: effects of glucose and of K+ channel blockers.
Brain research 1991;539(1):155-8.
1990: Mourre C; Widmann C; Lazdunski M
Saxitoxin-sensitive Na+ channels: presynaptic localization in cerebellum and hippocampus of neurological mutant mice.
Brain research 1990;533(2):196-202.
1990: Barbry P; Simon-Bouy B; Mattéi M G; Le Guern E; Jaume-Roig B; Chassande O; Ullrich A; Lazdunski M
Localization of the gene for amiloride binding protein on chromosome 7 and RFLP analysis in cystic fibrosis families.
Human genetics 1990;85(6):587-9.
1990: Mourre C; Smith M L; Siesjö B K; Lazdunski M
Brain ischemia alters the density of binding sites for glibenclamide, a specific blocker of ATP-sensitive K+ channels.
Brain research 1990;526(1):147-52.
1990: Schaeffer P; Vigne P; Frelin C; Lazdunski M
Identification and pharmacological properties of binding sites for the atypical thiazide diuretic, indapamide.
European journal of pharmacology 1990;182(3):503-8.
1990: Lambeau G; Schmid-Alliana A; Lazdunski M; Barhanin J
Identification and purification of a very high affinity binding protein for toxic phospholipases A2 in skeletal muscle.
The Journal of biological chemistry 1990;265(16):9526-32.
1990: Mourre C; Widmann C; Lazdunski M
Sulfonylurea binding sites associated with ATP-regulated K+ channels in the central nervous system: autoradiographic analysis of their distribution and ontogenesis, and of their localization in mutant mice cerebellum.
Brain research 1990;519(1-2):29-43.
1990: Séquier J M; Lazdunski M
Mast cell degranulating peptide induces the expression of the c-fos proto-oncogene in hippocampus.
European journal of pharmacology 1990;180(1):179-81.
1990: Schmid-Antomarchi H; Amoroso S; Fosset M; Lazdunski M
K+ channel openers activate brain sulfonylurea-sensitive K+ channels and block neurosecretion.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(9):3489-92.
1990: de Weille J R; Lazdunski M
ATP-sensitive K+ channels reveal the effects of intracellular chloride variations on cytoplasmic ATP concentrations and mitochondrial function.
Biochemical and biophysical research communications 1990;168(3):1137-42.
1990: Séquier J M; Brennand J; Barhanin J; Lazdunski M
Regional expression of a MCD-peptide and dendrotoxin I-sensitive voltage-dependent potassium channel in rat brain.
FEBS letters 1990;263(1):163-5.
1990: Auguste P; Hugues M; Gravé B; Gesquière J C; Maes P; Tartar A; Romey G; Schweitz H; Lazdunski M
Leiurotoxin I (scyllatoxin), a peptide ligand for Ca2(+)-activated K+ channels. Chemical synthesis, radiolabeling, and receptor characterization.
The Journal of biological chemistry 1990;265(8):4753-9.
1990: Amoroso S; Schmid-Antomarchi H; Fosset M; Lazdunski M
Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels.
Science (New York, N.Y.) 1990;247(4944):852-4.
1990: Barbry P; Chassande O; Marsault R; Lazdunski M; Frelin C
[3H]phenamil binding protein of the renal epithelium Na+ channel. Purification, affinity labeling, and functional reconstitution.
Biochemistry 1990;29(4):1039-45.
1990: Champigny G; Verrier B; Gérard C; Mauchamp J; Lazdunski M
Small conductance chloride channels in the apical membrane of thyroid cells.
FEBS letters 1990;259(2):263-8.
1990: Frelin C; Vigne P; Lazdunski M
The Na+/H+ exchange system in vascular smooth muscle cells.
Advances in nephrology from the Necker Hospital 1990;19():17-29.
1990: Schweitz H; Bidard J N; Lazdunski M
Purification and pharmacological characterization of peptide toxins from the black mamba (Dendroaspis polylepis) venom.
Toxicon : official journal of the International Society on Toxinology 1990;28(7):847-56.
1989: Schweitz H; Bidard J N; Maes P; Lazdunski M
Charybdotoxin is a new member of the K+ channel toxin family that includes dendrotoxin I and mast cell degranulating peptide.
Biochemistry 1989;28(25):9708-14.
1989: Pelzer S; Barhanin J; Pauron D; Trautwein W; Lazdunski M; Pelzer D
Diversity and novel pharmacological properties of Ca2+ channels in Drosophila brain membranes.
The EMBO journal 1989;8(8):2365-71.
1989: Bidard J N; Mourre C; Gandolfo G; Schweitz H; Widmann C; Gottesmann C; Lazdunski M
Analogies and differences in the mode of action and properties of binding sites (localization and mutual interactions) of two K+ channel toxins, MCD peptide and dendrotoxin I.
Brain research 1989;495(1):45-57.
1989: Rehm H; Pelzer S; Cochet C; Chambaz E; Tempel B L; Trautwein W; Pelzer D; Lazdunski M
Dendrotoxin-binding brain membrane protein displays a K+ channel activity that is stimulated by both cAMP-dependent and endogenous phosphorylations.
Biochemistry 1989;28(15):6455-60.
1989: Lambeau G; Barhanin J; Schweitz H; Qar J; Lazdunski M
Identification and properties of very high affinity brain membrane-binding sites for a neurotoxic phospholipase from the taipan venom.
The Journal of biological chemistry 1989;264(19):11503-10.
1989: Schweitz H; Stansfeld C E; Bidard J N; Fagni L; Maes P; Lazdunski M
Charybdotoxin blocks dendrotoxin-sensitive voltage-activated K+ channels.
FEBS letters 1989;250(2):519-22.
1989: Vigne P; Lazdunski M; Frelin C
The inotropic effect of endothelin-1 on rat atria involves hydrolysis of phosphatidylinositol.
FEBS letters 1989;249(2):143-6.
1989: Schmid A; Romey G; Barhanin J; Lazdunski M
SR33557, an indolizinsulfone blocker of Ca2+ channels: identification of receptor sites and analysis of its mode of action.
Molecular pharmacology 1989;35(6):766-73.
1989: Barbry P; Chassande O; Duval D; Rousseau B; Frelin C; Lazdunski M
Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels.
Biochemistry 1989;28(9):3744-9.
1989: Mourre C; Ben Ari Y; Bernardi H; Fosset M; Lazdunski M
Antidiabetic sulfonylureas: localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices.
Brain research 1989;486(1):159-64.
1989: Vigne P; Champigny G; Marsault R; Barbry P; Frelin C; Lazdunski M
A new type of amiloride-sensitive cationic channel in endothelial cells of brain microvessels.
The Journal of biological chemistry 1989;264(13):7663-8.
1989: de Weille J R; Schmid-Antomarchi H; Fosset M; Lazdunski M
Regulation of ATP-sensitive K+ channels in insulinoma cells: activation by somatostatin and protein kinase C and the role of cAMP.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2971-5.
1989: Romey G; Garcia L; Dimitriadou V; Pincon-Raymond M; Rieger F; Lazdunski M
Ontogenesis and localization of Ca2+ channels in mammalian skeletal muscle in culture and role in excitation-contraction coupling.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2933-7.
1989: de Weille J R; Fosset M; Schmid-Antomarchi H; Lazdunski M
Galanin inhibits dopamine secretion and activates a potassium channel in pheochromocytoma cells.
Brain research 1989;485(1):199-203.
1989: Vigne P; Lazdunski M; Frelin C
Guanabenz, guanochlor, guanoxan and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes.
European journal of pharmacology 1989;160(2):295-8.
1989: de Weille J R; Fosset M; Mourre C; Schmid-Antomarchi H; Bernardi H; Lazdunski M
Pharmacology and regulation of ATP-sensitive K+ channels.
Pflügers Archiv : European journal of physiology 1989;414 Suppl 1():S80-7.
1989: Fosset M; De Weille J; Schmid-Antomarchi H; Bernardi H; Lazdunski M
[Identification, function mechanisms and regulation of potassium channels sensitive to ATP which are targets of sulfonylureas used in the treatment of type II diabetes mellitus]
Journées annuelles de diabétologie de l'Hôtel-Dieu 1989;():7-11.
1989: Van Renterghem C; Vigne P; Barhanin J; Schmid-Alliana A; Frelin C; Lazdunski M
Molecular mechanism of endothelin-1 action on aortic cells.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S186-7.
1988: Bernardi H; Fosset M; Lazdunski M
Characterization, purification, and affinity labeling of the brain [3H]glibenclamide-binding protein, a putative neuronal ATP-regulated K+ channel.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9816-20.
1988: Fosset M; Schmid-Antomarchi H; de Weille J R; Lazdunski M
Somatostatin activates glibenclamide-sensitive and ATP-regulated K+ channels in insulinoma cells via a G-protein.
FEBS letters 1988;242(1):94-6.
1988: Vigne P; Breittmayer J P; Frelin C; Lazdunski M
Dual control of the intracellular pH in aortic smooth muscle cells by a cAMP-sensitive HCO3-/Cl- antiporter and a protein kinase C-sensitive Na+/H+ antiporter.
The Journal of biological chemistry 1988;263(34):18023-9.
1988: Van Renterghem C; Vigne P; Barhanin J; Schmid-Alliana A; Frelin C; Lazdunski M
Molecular mechanism of action of the vasoconstrictor peptide endothelin.
Biochemical and biophysical research communications 1988;157(3):977-85.
1988: Van Renterghem C; Romey G; Lazdunski M
Vasopressin modulates the spontaneous electrical activity in aortic cells (line A7r5) by acting on three different types of ionic channels.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9365-9.
1988: Romey G; Garcia L; Rieger F; Lazdunski M
Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling.
Biochemical and biophysical research communications 1988;156(3):1324-32.
1988: Frelin C; Barbry P; Chassande O; Vigne P; Lazdunski M
The structure of the amiloride sensitive apical Na+ channel from pig kidney.
Kidney international. Supplement 1988;26():S12-3.
1988: Vigne P; Breittmayer J P; Lazdunski M; Frelin C
The regulation of the cytoplasmic free Ca2+ concentration in aortic smooth muscle cells (A7r5 line) after stimulation by vasopressin and bombesin.
European journal of biochemistry / FEBS 1988;176(1):47-52.
1988: Frelin C; Barbry P; Vigne P; Chassande O; Cragoe E J; Lazdunski M
Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger.
Biochimie 1988;70(9):1285-90.
1988: Lombet A; Mourre C; Lazdunski M
Interaction of insecticides of the pyrethroid family with specific binding sites on the voltage-dependent sodium channel from mammalian brain.
Brain research 1988;459(1):44-53.
1988: Rehm H; Lazdunski M
Purification and subunit structure of a putative K+-channel protein identified by its binding properties for dendrotoxin I.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4919-23.
1988: Fosset M; De Weille J R; Green R D; Schmid-Antomarchi H; Lazdunski M
Antidiabetic sulfonylureas control action potential properties in heart cells via high affinity receptors that are linked to ATP-dependent K+ channels.
The Journal of biological chemistry 1988;263(17):7933-6.
1988: Frelin C; Vigne P; Ladoux A; Lazdunski M
The regulation of the intracellular pH in cells from vertebrates.
European journal of biochemistry / FEBS 1988;174(1):3-14.
1988: Rehm H; Lazdunski M
Existence of different populations of the dendrotoxin I binding protein associated with neuronal K+ channels.
Biochemical and biophysical research communications 1988;153(1):231-40.
1988: Mourre C; Bidard J N; Lazdunski M
High affinity receptors for the bee venom MCD peptide. Quantitative autoradiographic localization at different stages of brain development and relationship with MCD neurotoxicity.
Brain research 1988;446(1):106-12.
1988: Qar J; Barhanin J; Romey G; Henning R; Lerch U; Oekonomopulos R; Urbach H; Lazdunski M
A novel high affinity class of Ca2+ channel blockers.
Molecular pharmacology 1988;33(4):363-9.
1988: Rehm H; Bidard J N; Schweitz H; Lazdunski M
The receptor site for the bee venom mast cell degranulating peptide. Affinity labeling and evidence for a common molecular target for mast cell degranulating peptide and dendrotoxin I, a snake toxin active on K+ channels.
Biochemistry 1988;27(6):1827-32.
1988: Chassande O; Frelin C; Farahifar D; Jean T; Lazdunski M
The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation.
European journal of biochemistry / FEBS 1988;171(3):425-33.
1988: Barhanin J; Schmid A; Lazdunski M
Properties of structure and interaction of the receptor for omega-conotoxin, a polypeptide active on Ca2+ channels.
Biochemical and biophysical research communications 1988;150(3):1051-62.
1988: de Weille J; Schmid-Antomarchi H; Fosset M; Lazdunski M
ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1312-6.
1988: Lazdunski M; Barhanin J; Borsotto M; Cognard C; Cooper C; Coppola T; Fosset M; Galizzi J P; Hosey M M; Mourre C
Molecular properties of structure and regulation of the calcium channel.
Annals of the New York Academy of Sciences 1988;522():134-49.
1987: Frelin C; Vigne P; Barbry P; Lazdunski M
Molecular properties of amiloride action and of its Na+ transporting targets.
Kidney international 1987;32(6):785-93.
1987: Schmid-Antomarchi H; De Weille J; Fosset M; Lazdunski M
The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells.
The Journal of biological chemistry 1987;262(33):15840-4.
1987: Pauron D; Qar J; Barhanin J; Fournier D; Cuany A; Pralavorio M; Berge J B; Lazdunski M
Identification and affinity labeling of very high affinity binding sites for the phenylalkylamine series of Ca+ channel blockers in the Drosophila nervous system.
Biochemistry 1987;26(20):6311-5.
1987: Qar J; Galizzi J P; Fosset M; Lazdunski M
Receptors for diphenylbutylpiperidine neuroleptics in brain, cardiac, and smooth muscle membranes. Relationship with receptors for 1,4-dihydropyridines and phenylalkylamines and with Ca2+ channel blockade.
European journal of pharmacology 1987;141(2):261-8.
1987: Hosey M M; Barhanin J; Schmid A; Vandaele S; Ptasienski J; O'Callahan C; Cooper C; Lazdunski M
Photoaffinity labelling and phosphorylation of a 165 kilodalton peptide associated with dihydropyridine and phenylalkylamine-sensitive calcium channels.
Biochemical and biophysical research communications 1987;147(3):1137-45.
1987: Bidard J N; Gandolfo G; Mourre C; Gottesmann C; Lazdunski M
The brain response to the bee venom peptide MCD. Activation and desensitization of a hippocampal target.
Brain research 1987;418(2):235-44.
1987: Lombet A; Fosset M; Romey G; Jacomet Y; Lazdunski M
Identification in mammalian brain of an endogenous substance with Na+ channel blocking activities similar to those of tetrodotoxin.
Brain research 1987;417(2):327-34.
1987: Barbry P; Chassande O; Vigne P; Frelin C; Ellory C; Cragoe E J; Lazdunski M
Purification and subunit structure of the [3H]phenamil receptor associated with the renal apical Na+ channel.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(14):4836-40.
1987: Barhanin J; Coppola T; Schmid A; Borsotto M; Lazdunski M
The calcium channel antagonists receptor from rabbit skeletal muscle. Reconstitution after purification and subunit characterization.
European journal of biochemistry / FEBS 1987;164(3):525-31.
1987: Galizzi J P; Qar J; Fosset M; Van Renterghem C; Lazdunski M
Regulation of calcium channels in aortic muscle cells by protein kinase C activators (diacylglycerol and phorbol esters) and by peptides (vasopressin and bombesin) that stimulate phosphoinositide breakdown.
The Journal of biological chemistry 1987;262(15):6947-50.
1987: Vandaele S; Fosset M; Galizzi J P; Lazdunski M
Monoclonal antibodies that coimmunoprecipitate the 1,4-dihydropyridine and phenylalkylamine receptors and reveal the Ca2+ channel structure.
Biochemistry 1987;26(1):5-9.
1987: Cooper C L; Vandaele S; Barhanin J; Fosset M; Lazdunski M; Hosey M M
Purification and characterization of the dihydropyridine-sensitive voltage-dependent calcium channel from cardiac tissue.
The Journal of biological chemistry 1987;262(2):509-12.
1986: Galizzi J P; Fosset M; Romey G; Laduron P; Lazdunski M
Neuroleptics of the diphenylbutylpiperidine series are potent calcium channel inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7513-7.
1986: Schmid A; Barhanin J; Mourre C; Coppola T; Borsotto M; Lazdunski M
Antibodies reveal the cytolocalization and subunit structure of the 1,4-dihydropyridine component of the neuronal Ca2+ channel.
Biochemical and biophysical research communications 1986;139(3):996-1002.
1986: Qar J; Schweitz H; Schmid A; Lazdunski M
A polypeptide toxin from the coral Goniopora. Purification and action on Ca2+ channels.
FEBS letters 1986;202(2):331-6.
1986: Schmid A; Barhanin J; Coppola T; Borsotto M; Lazdunski M
Immunochemical analysis of subunit structures of 1,4-dihydropyridine receptors associated with voltage-dependent Ca2+ channels in skeletal, cardiac, and smooth muscles.
Biochemistry 1986;25(12):3492-5.
1986: Cognard C; Romey G; Galizzi J P; Fosset M; Lazdunski M
Dihydropyridine-sensitive Ca2+ channels in mammalian skeletal muscle cells in culture: electrophysiological properties and interactions with Ca2+ channel activator (Bay K8644) and inhibitor (PN 200-110).
Proceedings of the National Academy of Sciences of the United States of America 1986;83(5):1518-22.
1986: Lombet A; Laduron P; Mourre C; Jacomet Y; Lazdunski M
Axonal transport of Na+,K+-ATPase identified as a ouabain binding site in rat sciatic nerve.
Neuroscience letters 1986;64(2):177-83.
1986: Galizzi J P; Borsotto M; Barhanin J; Fosset M; Lazdunski M
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.
The Journal of biological chemistry 1986;261(3):1393-7.
1986: Lazdunski M; Barhanin J; Borsotto M; Fosset M; Galizzi J P; Renaud J F; Romey G; Schmid A
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation.
Journal of cardiovascular pharmacology 1986;8 Suppl 8():S13-9.
1985: Galizzi J P; Fosset M; Lazdunski M
Characterization of the Ca2+ coordination site regulating binding of Ca2+ channel inhibitors d-cis-diltiazem, (+/-)bepridil and (-)desmethoxyverapamil to their receptor site in skeletal muscle transverse tubule membranes.
Biochemical and biophysical research communications 1985;132(1):49-55.
1985: Lombet A; Laduron P; Mourre C; Jacomet Y; Lazdunski M
Axonal transport of the voltage-dependent Na+ channel protein identified by its tetrodotoxin binding site in rat sciatic nerves.
Brain research 1985;345(1):153-8.
1984: Galizzi J P; Fosset M; Lazdunski M
Properties of receptors for the Ca2+-channel blocker verapamil in transverse-tubule membranes of skeletal muscle. Stereospecificity, effect of Ca2+ and other inorganic cations, evidence for two categories of sites and effect of nucleoside triphosphates.
European journal of biochemistry / FEBS 1984;144(2):211-5.
1984: Galizzi J P; Fosset M; Lazdunski M
[3H] verapamil binding sites in skeletal muscle transverse tubule membranes.
Biochemical and biophysical research communications 1984;118(1):239-45.
1983: Vincent J P; Bidard J N; Lazdunski M; Romey G; Tourneur Y; Vignon J
Identification and properties of phencyclidine-binding sites in nervous tissues.
Federation proceedings 1983;42(9):2570-3.
1982: Tourneur Y; Romey G; Lazdunski M
Phencyclidine blockade of sodium and potassium channels in neuroblastoma cells.
Brain research 1982;245(1):154-8.
1981: Frelin C; Vigne P; Ponzio G; Romey G; Tourneur Y; Husson H P; Lazdunski M
The interaction of ervatamine and epiervatamine with the action potential Na+ ionophore.
Molecular pharmacology 1981;20(1):107-12.

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