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Katarina Le Blanc

Research Profile

Anatomy

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Graft vs Host Disease

Physiology

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Infants

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Sofia Berglund; Jens Gertow; Katarina Le Blanc; Per Ljungman; Mats Remberger; Olle Ringdén; Petter Svenberg; Michael Uhlin; Mehmet Uzunel; Jacek Winiarski; Jonas Mattsson
Factors with an impact on chimerism development and long-term survival after umbilical cord blood transplantation.
L von Bahr; I Batsis; M Hägg; Guido Moll; Olle Ringden; Berit Sundberg; Attila Szakos; Mehmet Uzunel; Katarina Le Blanc
Analysis of tissues following mesenchymal stromal cell therapy in humans indicates limited long-term engraftment and no ectopic tissue formation.
Guido Moll; Bo Nilsson; Kristina Nilsson-Ekdahl; Ida Rasmusson-Duprez; Olle Ringdén; Javier Sanchez; Yuji Teramura; Lena von Bahr; Anne-Marie Connolly-Andersen; Graciela Elgue; Lillemor Funke; Osama A Hamad; Olle Korsgren; Helena Lönnies; Peetra U Magnusson; Katarina Le Blanc
Are therapeutic human mesenchymal stromal cells compatible with human blood?

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2012: Sofia Berglund; Jens Gertow; Katarina Le Blanc; Per Ljungman; Mats Remberger; Olle Ringdén; Petter Svenberg; Michael Uhlin; Mehmet Uzunel; Jacek Winiarski; Jonas Mattsson
Factors with an impact on chimerism development and long-term survival after umbilical cord blood transplantation.
Transplantation 2012;94(10):1066-74.
2012: L von Bahr; I Batsis; M Hägg; Guido Moll; Olle Ringden; Berit Sundberg; Attila Szakos; Mehmet Uzunel; Katarina Le Blanc
Analysis of tissues following mesenchymal stromal cell therapy in humans indicates limited long-term engraftment and no ectopic tissue formation.
Stem cells (Dayton, Ohio) 2012;30(7):1575-8.
2012: Guido Moll; Bo Nilsson; Kristina Nilsson-Ekdahl; Ida Rasmusson-Duprez; Olle Ringdén; Javier Sanchez; Yuji Teramura; Lena von Bahr; Anne-Marie Connolly-Andersen; Graciela Elgue; Lillemor Funke; Osama A Hamad; Olle Korsgren; Helena Lönnies; Peetra U Magnusson; Katarina Le Blanc
Are therapeutic human mesenchymal stromal cells compatible with human blood?
Stem cells (Dayton, Ohio) 2012;30(7):1565-74.
2012: Lindsay C Davies; Cecilia Götherström; Katarina Le Blanc; Matthew Locke; Helena Lönnies; Kerstin Rosendahl; Berit Sundberg; Phil Stephens
Oral mucosal progenitor cells are potently immunosuppressive in a dose-independent manner.
Stem cells and development 2012;21(9):1478-87.
2012: Johan Lundberg; Erik Södersten; Erik Sundström; Tommy Andersson; Ola Hermanson; Katarina Le Blanc; Staffan Holmin
Targeted intra-arterial transplantation of stem cells to the injured CNS is more effective than intravenous administration: engraftment is dependent on cell type and adhesion molecule expression.
Cell transplantation 2012;21(1):333-43.
2011: Dimitrios Mougiakakos; Regina Jitschin; C Christian Johansson; Riki Okita; Rolf Kiessling; Katarina Le Blanc
The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells.
Blood 2011;117(18):4826-35.
2011: Mikael Sundin; Pádraig D'arcy; C Christian Johansson; A John Barrett; Helena Lönnies; Berit Sundberg; Silvia Nava; Rolf Kiessling; Dimitrios Mougiakakos; Katarina Le Blanc
Multipotent mesenchymal stromal cells express FoxP3: a marker for the immunosuppressive capacity?
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(4):336-42.
2011: O Ringden; Katarina Le Blanc
Mesenchymal stem cells for treatment of acute and chronic graft-versus-host disease, tissue toxicity and hemorrhages.
Best practice & research. Clinical haematology 2011;24(1):65-72.
2011: Cecilia Götherström; Andreas Lundqvist; Ida Rasmusson Duprez; Richard Childs; Louise Berg; Katarina Le Blanc
Fetal and adult multipotent mesenchymal stromal cells are killed by different pathways.
Cytotherapy 2011;13(3):269-78.
2011: Guido Moll; Dimitrios Mougiakakos; Graciela Elgue; Regina Jitschin; John D Lambris; Katarina Le Blanc; Lena Lönnies; Kristina Nilsson-Ekdahl; Ida Rasmusson-Duprez; Olle Ringdén; Berit Sundberg; Lena von Bahr; Bo Nilsson
Mesenchymal stromal cells engage complement and complement receptor bearing innate effector cells to modulate immune responses.
PloS one 2011;6(7):e21703.
2009: Katarina Le Blanc; A John Barrett; Marie Schaffer; Hans Hägglund; Per Ljungman; Olle Ringdén; Mats Remberger
Lymphocyte recovery is a major determinant of outcome after matched unrelated myeloablative transplantation for myelogenous malignancies.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(9):1108-15.
2009: R Schäfer; Massimo Dominici; I Müller; E Horwitz; T Asahara; Jeff W M Bulte; K Bieback; Katarina Le Blanc; H J Bühring; M C Capogrossi; F Dazzi; R Gorodetsky; R Henschler; Rupert Handgretinger; J Kajstura; P J Kluger; C Lange; I von Luettichau; H Mertsching; H Schrezenmeier; K D Sievert; Dirk STRUNK; C Verfaillie; Hinnak Northoff
Basic research and clinical applications of non-hematopoietic stem cells, 4-5 April 2008, Tubingen, Germany.
Cytotherapy 2009;11(2):245-55.
2009: H Samuelsson; Olle Ringdén; Helena Lönnies; Katarina Le Blanc
Optimizing in vitro conditions for immunomodulation and expansion of mesenchymal stromal cells.
Cytotherapy 2009;11(2):129-36.
2008: Mikael Sundin; Anna Lindblom; Claes Orvell; A John Barrett; Berit Sundberg; Emma Watz; Agneta Wikman; Kristina Broliden; Katarina Le Blanc
Persistence of human parvovirus B19 in multipotent mesenchymal stromal cells expressing the erythrocyte P antigen: implications for transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(10):1172-9.
2008: Katarina Le Blanc; Francesco Frassoni; Lynne Ball; Franco Locatelli; Helene Roelofs; Ian Lewis; Edoardo Lanino; Berit Sundberg; Maria Ester Bernardo; Mats Remberger; Giorgio Dini; R Maarten Egeler; Andrea Bacigalupo; Willem Fibbe; Olle Ringdén
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study.
Lancet 2008;371(9624):1579-86.
2008: Katarina Le Blanc; W Fibbe
A new cell therapy registry coordinated by the European Group for Blood and Marrow Transplantation (EBMT).
Bone marrow transplantation 2008;41(3):319.
2008: Katarina Le Blanc
Lymphocyte recovery: an overlooked contribution to autologous stem cell transplant outcome.
Cytotherapy 2008;10(5):441-2.
2008: Mikael Sundin; M Remberger; H Lönnies; Berit Sundberg; Olle Ringdén; Katarina Le Blanc
No increased trapping of multipotent mesenchymal stromal cells in bone marrow filters compared with other bone marrow cells.
Cytotherapy 2008;10(3):238-42.
2007: Katarina Le Blanc; Olle Ringdén
Immunomodulation by mesenchymal stem cells and clinical experience.
Journal of internal medicine 2007;262(5):509-25.
2007: Olle Ringdén; Mehmet Uzunel; Berit Sundberg; L Lönnies; S Nava; J Gustafsson; L Henningsohn; Katarina Le Blanc
Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon.
Leukemia 2007;21(11):2271-6.
2007: Katarina Le Blanc; Håkan Samuelsson; Lena Lönnies; Mikael Sundin; Olle Ringdén
Generation of immunosuppressive mesenchymal stem cells in allogeneic human serum.
Transplantation 2007;84(8):1055-9.
2007: Ida Rasmusson; Michael Uhlin; Katarina Le Blanc; Victor Levitsky
Mesenchymal stem cells fail to trigger effector functions of cytotoxic T lymphocytes.
Journal of leukocyte biology 2007;82(4):887-93.
2007: Zuzana Hassan; Mats Remberger; Petter Svenberg; Maria Elbander; Brigitta Omazic; Jonas Mattsson; Réka Conrad; Britt-Marie Svahn; Anders Ahlgren; Darius Sairafi; Johan Aschan; Katarina Le Blanc; Lisbeth Barkholt; Olle Ringdén
Hemorrhagic cystitis: a retrospective single-center survey.
Clinical transplantation 2007;21(5):659-67.
2007: Mikael Sundin; Olle Ringdén; Berit Sundberg; Silvia Nava; Cecilia Götherström; Katarina Le Blanc
No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients.
Haematologica 2007;92(9):1208-15.
2007: Katarina Le Blanc; H Samuelsson; B Gustafsson; Mats Remberger; Berit Sundberg; J Arvidson; P Ljungman; Helena Lönnies; S Nava; Olle Ringdén
Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells.
Leukemia 2007;21(8):1733-8.
2007: Ida Rasmusson; Katarina Le Blanc; Berit Sundberg; Olle Ringdén
Mesenchymal stem cells stimulate antibody secretion in human B cells.
Scandinavian journal of immunology 2007;65(4):336-43.
2007: Fabrício F Costa; Katarina Le Blanc; Bertha Brodin
Concise review: cancer/testis antigens, stem cells, and cancer.
Stem cells (Dayton, Ohio) 2007;25(3):707-11.
2007: R Schäfer; Massimo Dominici; I Müller; F Dazzi; K Bieback; K Godthardt; Katarina Le Blanc; R Meisel; R Pochampally; R Richter; T Skutella; G Steinhoff; M Mitterberger; Hp Wendel; Jakub Wiskirchen; Rupert Handgretinger; Hinnak Northoff
Progress in characterization, preparation and clinical applications of non-hematopoietic stem cells, 29-30 September 2006, Tübingen, Germany.
Cytotherapy 2007;9(4):397-405.
2007: Alan Tyndall; Ulrich A Walker; Andrew Cope; Francesco Dazzi; Cosimo De Bari; Willem Fibbe; Serena Guiducci; Simon Jones; Christian Jorgensen; Katarina Le Blanc; Frank P Luyten; Dennis McGonagle; Ivan Martin; Chiara Bocelli Tyndall; Giuseppina Pennesi; Vito Pistoia; Costantino Pitzalis; Antonio Uccelli; Nico M Wulffraat; Marc Feldmann
Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005.
Arthritis research & therapy 2007;9(1):301.
2006: Katarina Le Blanc; Olle Ringdén
Mesenchymal stem cells: properties and role in clinical bone marrow transplantation.
Current opinion in immunology 2006;18(5):586-91.
2006: Mikael Sundin; Katarina Le Blanc; Olle Ringdén; Lisbeth Barkholt; Brigitta Omazic; Christina Lergin; Victor Levitsky; Mats Remberger
The role of HLA mismatch, splenectomy and recipient Epstein-Barr virus seronegativity as risk factors in post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation.
Haematologica 2006;91(8):1059-67.
2006: Olle Ringdén; Petter Svenberg; Katarina Le Blanc; Jonas Mattsson; Mats Remberger
Myeloablative conditioning for hematopoietic stem-cell transplantation in patients with non-malignant diseases.
Bone marrow transplantation 2006;38(4):321-2.
2006: Mikael Sundin; C Orvell; Ida Rasmusson; Berit Sundberg; Olle Ringdén; Katarina Le Blanc
Mesenchymal stem cells are susceptible to human herpesviruses, but viral DNA cannot be detected in the healthy seropositive individual.
Bone marrow transplantation 2006;37(11):1051-9.
2006: Olle Ringdén; Mehmet Uzunel; Ida Rasmusson; Mats Remberger; Berit Sundberg; Helena Lönnies; Hanns-Ulrich Marschall; Aldona Dlugosz; Attila Szakos; Zuzana Hassan; Brigitta Omazic; Johan Aschan; Lisbeth Barkholt; Katarina Le Blanc
Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease.
Transplantation 2006;81(10):1390-7.
2006: Olle Ringdén; Mats Remberger; Britt-Marie Svahn; Lisbeth Barkholt; Jonas Mattsson; Johan Aschan; Katarina Le Blanc; Britt Gustafsson; Zuzana Hassan; Brigitta Omazic; Petter Svenberg; Göran Solders; Ulrika von Döbeln; Jacek Winiarski; Per Ljungman; Gunilla Malm
Allogeneic hematopoietic stem cell transplantation for inherited disorders: experience in a single center.
Transplantation 2006;81(5):718-25.
2006: Katarina Le Blanc
Mesenchymal stromal cells: Tissue repair and immune modulation.
Cytotherapy 2006;8(6):559-61.
2006: Massimo Dominici; Katarina Le Blanc; I Mueller; I Slaper-Cortenbach; Fc Marini; Ds Krause; Rj Deans; A Keating; Dj Prockop; Edwin Horwitz
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement.
Cytotherapy 2006;8(4):315-7.
2005: Olle Ringdén; Katarina Le Blanc
Allogeneic hematopoietic stem cell transplantation: state of the art and new perspectives.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2005;113(11-12):813-30.
2005: Andrea Dicker; Katarina Le Blanc; Gaby Aström; Vanessa van Harmelen; Cecilia Götherström; Lennart Blomqvist; Peter Arner; Mikael Rydén
Functional studies of mesenchymal stem cells derived from adult human adipose tissue.
Experimental cell research 2005;308(2):283-90.
2005: Cecilia Götherström; Anne West; Johan Liden; Mehmet Uzunel; Riitta Lahesmaa; Katarina Le Blanc
Difference in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells.
Haematologica 2005;90(8):1017-26.
2005: Katarina Le Blanc; Cecilia Götherström; Olle Ringdén; Moustapha Hassan; Robert McMahon; Edwin Horwitz; Göran Anneren; Ove Axelsson; Janice Nunn; Uwe Ewald; Solveig Nordén-Lindeberg; Monika Jansson; Ann Dalton; Eva Aström; Magnus Westgren
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta.
Transplantation 2005;79(11):1607-14.
2005: Olle T H Ringdén; Katarina Le Blanc; Mats Remberger
Granulocyte and granulocyte-macrophage colony-stimulating factors in allografts: uses, misuses, misconceptions, and future applications.
Experimental hematology 2005;33(5):505-12.
2005: Katarina Le Blanc; Olle Ringdén
Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(5):321-34.
2005: Ida Rasmusson; Olle Ringdén; Berit Sundberg; Katarina Le Blanc
Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms.
Experimental cell research 2005;305(1):33-41.
2005: Garth Cronwright; Katarina Le Blanc; Cecilia Götherström; Pádraig Darcy; Monika Ehnman; Bertha Brodin
Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression.
Cancer research 2005;65(6):2207-15.
2005: Edwin M Horwitz; Katarina Le Blanc; Massimo Dominici; I Mueller; I Slaper-Cortenbach; F C Marini; R J Deans; D S Krause; A Keating
Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement.
Cytotherapy 2005;7(5):393-5.
2005: Katarina Le Blanc; Mark F Pittenger
Mesenchymal stem cells: progress toward promise.
Cytotherapy 2005;7(1):36-45.
2004: Katarina Le Blanc; Mats Remberger; Mehmet Uzunel; Jonas Mattsson; Lisbeth Barkholt; Olle Ringdén
A comparison of nonmyeloablative and reduced-intensity conditioning for allogeneic stem-cell transplantation.
Transplantation 2004;78(7):1014-20.
2004: Katarina Le Blanc; Ida Rasmusson; Cecilia Götherström; C Seidel; Berit Sundberg; Mikael Sundin; Kerstin Rosendahl; Charlotte Tammik; Olle Ringdén
Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytes.
Scandinavian journal of immunology 2004;60(3):307-15.
2004: Katarina Le Blanc; Ida Rasmusson; Berit Sundberg; Cecilia Götherström; Moustapha Hassan; Mehmet Uzunel; Olle Ringdén
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells.
Lancet 2004;363(9419):1439-41.
2004: Karl-Henrik Grinnemo; A Månsson; Göran Dellgren; D Klingberg; E Wardell; Viktor Drvota; Charlotte Tammik; J Holgersson; Olle Ringdén; Christer Sylvén; Katarina Le Blanc
Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium.
The Journal of thoracic and cardiovascular surgery 2004;127(5):1293-300.
2004: Olle Ringdén; Marie Schaffer; Katarina Le Blanc; Ulla Persson; Dan Hauzenberger; Mohammad R Abedi; Olle Olerup; Per Ljungman; Mats Remberger
Which donor should be chosen for hematopoietic stem cell transplantation among unrelated HLA-A, -B, and -DRB1 genomically identical volunteers?
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(2):128-34.
2004: Olle Ringdén; Myriam Labopin; Norbert-Claude Gorin; Katarina Le Blanc; Vanderson Rocha; Eliane Gluckman; Jules Reiffers; William Arcese; Jaak M Vossen; Jean-Pierre Jouet; Catherine Cordonnier; Francesco Frassoni
Treatment with granulocyte colony-stimulating factor after allogeneic bone marrow transplantation for acute leukemia increases the risk of graft-versus-host disease and death: a study from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(3):416-23.
2004: Cecilia Götherström; Olle Ringdén; Charlotte Tammik; Eva Zetterberg; Magnus Westgren; Katarina Le Blanc
Immunologic properties of human fetal mesenchymal stem cells.
American journal of obstetrics and gynecology 2004;190(1):239-45.
2003: Mikael Rydén; Andrea Dicker; Cecilia Götherström; Gaby Aström; Charlotte Tammik; Peter Arner; Katarina Le Blanc
Functional characterization of human mesenchymal stem cell-derived adipocytes.
Biochemical and biophysical research communications 2003;311(2):391-7.
2003: Ida Rasmusson; Olle Ringdén; Berit Sundberg; Katarina Le Blanc
Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells.
Transplantation 2003;76(8):1208-13.
2003: Katarina Le Blanc; Charlotte Tammik; Kerstin Rosendahl; Eva Zetterberg; Olle Ringdén
HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells.
Experimental hematology 2003;31(10):890-6.
2003: Katarina Le Blanc; Olle Ringdén; Mats Remberger
A low body mass index is correlated with poor survival after allogeneic stem cell transplantation.
Haematologica 2003;88(9):1044-52.
2003: Cecilia Götherström; Olle Ringdén; Magnus Westgren; Charlotte Tammik; Katarina Le Blanc
Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells.
Bone marrow transplantation 2003;32(3):265-72.
2003: Katarina Le Blanc
Immunomodulatory effects of fetal and adult mesenchymal stem cells.
Cytotherapy 2003;5(6):485-9.
2003: Katarina Le Blanc; L Tammik; B Sundberg; S E Haynesworth; O Ringdén
Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex.
Scandinavian journal of immunology 2003;57(1):11-20.