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Yves Le Bouc

Research Profile

Chemicals & Drugs

Disorders

Anatomy

Chromosomes, Human, Pair 11

Physiology

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Blotting, Southern

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Irène Netchine; Sylvie Rossignol; Salah Azzi; Yves Le Bouc
Epigenetic anomalies in childhood growth disorders.
Emmanuelle Duron; Jacques Epelbaum; Benoît Funalot; Pierre Jouanny; Yves Le Bouc; Florence Pasquier; Laurent Quinquis; Jean-Marc Treluyer; Cécile Viollet; Joel Belmin; Nadège Brunel; Joel Coste; Olivier Hanon
Insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Alzheimer's disease.
Emeline Renard; Georges Weryha; M Klein; Christelle Langbour-Remy; Yves Le Bouc; Thomas Cuny
Severe hypoglycemia with "Big"-IGF-2 oversecretion by a giant phyllode tumor of the breast: a rare case of non-islet cell tumor-induced hypoglycemia (NICTH).

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2013: Irène Netchine; Sylvie Rossignol; Salah Azzi; Yves Le Bouc
Epigenetic anomalies in childhood growth disorders.
Nestlé Nutrition Institute workshop series 2013;71():65-73.
2012: Emmanuelle Duron; Jacques Epelbaum; Benoît Funalot; Pierre Jouanny; Yves Le Bouc; Florence Pasquier; Laurent Quinquis; Jean-Marc Treluyer; Cécile Viollet; Joel Belmin; Nadège Brunel; Joel Coste; Olivier Hanon
Insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Alzheimer's disease.
The Journal of clinical endocrinology and metabolism 2012;97(12):4673-81.
2012: Emeline Renard; Georges Weryha; M Klein; Christelle Langbour-Remy; Yves Le Bouc; Thomas Cuny
Severe hypoglycemia with "Big"-IGF-2 oversecretion by a giant phyllode tumor of the breast: a rare case of non-islet cell tumor-induced hypoglycemia (NICTH).
Annales d'endocrinologie 2012;73(5):488-91.
2012: Lukas Huijbregts; Yves Le Bouc; Juliane Leger; Catherine Roze; Patrizia Alberti; Giulia Bonafe; Jean-Claude Carel; Muriel Houang; Nicolas de Roux
DNA polymorphisms of the KiSS1 3' untranslated region interfere with the folding of a G-rich sequence into G-quadruplex.
Molecular and cellular endocrinology 2012;351(2):239-48.
2012: Yves Le Bouc; Frédéric Brioude
[Is there a relationship between the growth hormone dose and tumoral or cardiovascular complications?].
Bulletin de l'Académie nationale de médecine 2012;196(1):127-35; discussion 135-7.
2012: Irène Netchine; Sylvie Rossignol; Salah Azzi; Fréderic Brioude; Yves Le Bouc
Imprinted anomalies in fetal and childhood growth disorders: the model of Russell-Silver and Beckwith-Wiedemann syndromes.
Endocrine development 2012;23():60-70.
2011: Irène Netchine; Salah Azzi; Yves Le Bouc; Martin O Savage
IGF1 molecular anomalies demonstrate its critical role in fetal, postnatal growth and brain development.
Best practice & research. Clinical endocrinology & metabolism 2011;25(1):181-90.
2011: Salah Azzi; Virginie Steunou; Alexandra Rousseau; Sylvie Rossignol; Nathalie Thibaud; Fabienne Danton; Marilyne Le Jule; Christine Gicquel; Yves Le Bouc; Irène Netchine
Allele-specific methylated multiplex real-time quantitative PCR (ASMM RTQ-PCR), a powerful method for diagnosing loss of imprinting of the 11p15 region in Russell Silver and Beckwith Wiedemann syndromes.
Human mutation 2011;32(2):249-58.
2011: J Demars; Yves Le Bouc; Assam El-Osta; C Gicquel
Epigenetic and genetic mechanisms of abnormal 11p15 genomic imprinting in Silver-Russell and Beckwith-Wiedemann syndromes.
Current medicinal chemistry 2011;18(12):1740-50.
2010: Salah Azzi; Sylvie Rossignol; Yves Le Bouc; Irène Netchine
Lessons from imprinted multilocus loss of methylation in human syndromes: A step toward understanding the mechanisms underlying these complex diseases.
Epigenetics : official journal of the DNA Methylation Society 2010;5(5):373-7.
2010: Julie Demars; Mansur Ennuri Shmela; Sylvie Rossignol; Jun Okabe; Irène Netchine; Salah Azzi; Sylvie Cabrol; Cédric Le Caignec; Albert David; Yves Le Bouc; Assam El-Osta; Christine Gicquel
Analysis of the IGF2/H19 imprinting control region uncovers new genetic defects, including mutations of OCT-binding sequences, in patients with 11p15 fetal growth disorders.
Human molecular genetics 2010;19(5):803-14.
2010: Yves Le Bouc; Sylvie Rossignol; Salah Azzi; Frédéric Brioude; Sylvie Cabrol; Christine Gicquel; Irène Netchine
[Epigenetics, genomic imprinting and developmental disorders].
Bulletin de l'Académie nationale de médecine 2010;194(2):287-97; discussion 297-300.
2009: Salah Azzi; Sylvie Rossignol; Virginie Steunou; Theo Sas; Nathalie Thibaud; Fabienne Danton; Maryline Le Jule; Claudine Heinrichs; Sylvie Cabrol; Christine Gicquel; Yves Le Bouc; Irene Netchine
Multilocus methylation analysis in a large cohort of 11p15-related foetal growth disorders (Russell Silver and Beckwith Wiedemann syndromes) reveals simultaneous loss of methylation at paternal and maternal imprinted loci.
Human molecular genetics 2009;18(24):4724-33.
2009: Jacques Pantel; Marie Legendre; Sylvie Nivot; Séverine Morisset; Marie-Pierre Vie-Luton; Yves Le Bouc; Jacques Epelbaum; Serge Amselem
Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor.
The Journal of clinical endocrinology and metabolism 2009;94(11):4334-41.
2009: Irène Netchine; Salah Azzi; Muriel Houang; Danielle Seurin; Laurence Perin; Jean-Marc Ricort; Claudine Daubas; Christine Legay; Jan Mester; Robert Herich; François Godeau; Yves Le Bouc
Partial primary deficiency of insulin-like growth factor (IGF)-I activity associated with IGF1 mutation demonstrates its critical role in growth and brain development.
The Journal of clinical endocrinology and metabolism 2009;94(10):3913-21.
2009: Peter Kamenicky; Christine Dos Santos; Consuelo Espinosa; Sylvie Salenave; Françoise Galland; Yves Le Bouc; Patrick Maison; Pierre Bougnères; Philippe Chanson
D3 GH receptor polymorphism is not associated with IGF1 levels in untreated acromegaly.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(2):231-5.
2009: Laurent Kappeler; Carlos De Magalhaes Filho; Patricia Leneuve; Jie Xu; Nadège Brunel; Christos Chatziantoniou; Yves Le Bouc; Martin Holzenberger
Early postnatal nutrition determines somatotropic function in mice.
Endocrinology 2009;150(1):314-23.
2008: Sylvie Rossignol; Irène Netchine; Yves Le Bouc; Christine Gicquel
Epigenetics in Silver-Russell syndrome.
Best practice & research. Clinical endocrinology & metabolism 2008;22(3):403-14.
2008: Christine Gicquel; Assam El-Osta; Yves Le Bouc
Epigenetic regulation and fetal programming.
Best practice & research. Clinical endocrinology & metabolism 2008;22(1):1-16.
2007: Martine Duclos; Michel Guinot; Yves Le Bouc
Cortisol and GH: odd and controversial ideas.
Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2007;32(5):895-903.
2007: Marie-France Portnoï; Nicolas Gruchy; Sandrine Marlin; Lina Finkel; Françoise Denoyelle; Christèle Dubourg; Sylvie Odent; Jean-Pierre Siffroi; Yves Le Bouc; Muriel Houang
Midline defects in deletion 18p syndrome: clinical and molecular characterization of three patients.
Clinical dysmorphology 2007;16(4):247-52.
2007: Irène Netchine; Sylvie Rossignol; Marie-Noëlle Dufourg; Salah Azzi; Alexandra Rousseau; Laurence Perin; Muriel Houang; Virginie Steunou; Blandine Esteva; Nathalie Thibaud; Marie-Charles Raux Demay; Fabienne Danton; Elzbieta Petriczko; Anne-Marie Bertrand; Claudine Heinrichs; Jean-Claude Carel; Guy-André Loeuille; Graziella Pinto; Marie-Line Jacquemont; Christine Gicquel; Sylvie Cabrol; Yves Le Bouc
11p15 imprinting center region 1 loss of methylation is a common and specific cause of typical Russell-Silver syndrome: clinical scoring system and epigenetic-phenotypic correlations.
The Journal of clinical endocrinology and metabolism 2007;92(8):3148-54.
2007: Lionel Groussin; Jérôme Bertherat; Christine Gicquel; Yves Le Bouc; Xavier Bertagna
Insights into the molecular biology of adrenocortical tumors.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2007;115(3):175-8.
2007: David Aguiar Bujanda; José C Rivero Vera; Miguel Angel Cabrera Suárez; José Aguiar Morales; Rémy Christol; Uriel Bohn Sarmiento; Casimira Domínguez Cabrera; Yves Le Bouc
Hypoglycemic coma secondary to big insulin-like growth factor II secretion by a giant phyllodes tumor of the breast.
The breast journal 2007;13(2):189-91.
2007: Michel Guinot; Martine Duclos; N Idres; J C Souberbielle; A Megret; Yves Le Bouc
Value of basal serum cortisol to detect corticosteroid-induced adrenal insufficiency in elite cyclists.
European journal of applied physiology 2007;99(3):205-16.
2007: Fanny Mochel; Perrine Charles; François Seguin; Julie Barritault; Christiane Coussieu; Laurence Perin; Yves Le Bouc; Christiane Gervais; Guislaine Carcelain; Anne Vassault; JOSUE FEINGOLD; Daniel Rabier; Alexandra Durr
Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression.
PloS one 2007;2(7):e647.
2006: Françoise Galland; Peter Kamenicky; Hélène Affres; Yves Reznik; Dominique Pontvert; Yves Le Bouc; Jacques Young; Philippe Chanson
McCune-Albright syndrome and acromegaly: effects of hypothalamopituitary radiotherapy and/or pegvisomant in somatostatin analog-resistant patients.
The Journal of clinical endocrinology and metabolism 2006;91(12):4957-61.
2006: Sylvie Rossignol; Virginie Steunou; Céline Chalas; Antoine Kerjean; Muriel Rigolet; E Viegas-Pequignot; Pierre Jouannet; Yves Le Bouc; Christine Gicquel
The epigenetic imprinting defect of patients with Beckwith-Wiedemann syndrome born after assisted reproductive technology is not restricted to the 11p15 region.
Journal of medical genetics 2006;43(12):902-7.
2006: Nadia Ben Lagha; Danielle Seurin; Yves Le Bouc; Michel Binoux; Ariane Berdal; Pierrette Menuelle; Sylvie Babajko
Insulin-like growth factor binding protein (IGFBP-1) involvement in intrauterine growth retardation: study on IGFBP-1 overexpressing transgenic mice.
Endocrinology 2006;147(10):4730-7.
2006: Christèle Desbois-Mouthon; Dominique Wendum; Axelle Cadoret; Colette Rey; Patricia Leneuve; Annick Blaise; Chantal Housset; François Tronche; Yves Le Bouc; Martin Holzenberger
Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):773-5.
2006: Laurent Kappeler; Carlos De Magalhaes Filho; Yves Le Bouc; Martin Holzenberger
[Ageing, genetics and the somatotropic axis].
Médecine sciences : M/S 2006;22(3):259-65.
2006: Jacques Pantel; Marie Legendre; Sylvie Cabrol; Latifa Hilal; Yassir Hajaji; Séverine Morisset; Sylvie Nivot; Marie-Pierre Vie-Luton; Dominique Grouselle; Marc De Kerdanet; Abdelkrim Kadiri; Jacques Epelbaum; Yves Le Bouc; Serge Amselem
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.
The Journal of clinical investigation 2006;116(3):760-8.
2006: MC Raux-Demay; J P Magny; N Idrès; A Grimfeld; Yves Le Bouc
Use of the low-dose corticotropin stimulation test for the monitoring of children with asthma treated with inhaled corticosteroids.
Hormone research 2006;66(2):51-60.
2006: Christine Gicquel; Yves Le Bouc
Hormonal regulation of fetal growth.
Hormone research 2006;65 Suppl 3():28-33.
2006: Jean-Marie Limal; Béatrice Parfait; Sylvie Cabrol; Damien Bonnet; Bruno Leheup; Stanislas LYONNET; Michel Vidaud; Yves Le Bouc
Noonan syndrome: relationships between genotype, growth, and growth factors.
The Journal of clinical endocrinology and metabolism 2006;91(1):300-6.
2005: Christine Gicquel; Sylvie Rossignol; Sylvie Cabrol; Muriel Houang; Virginie Steunou; Véronique Barbu; Fabienne Danton; Nathalie Thibaud; Martine Le Merrer; Lydie Burglen; Anne-Marie Bertrand; Irène Netchine; Yves Le Bouc
Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome.
Nature genetics 2005;37(9):1003-7.
2005: Géraldine Bienvenu; Danielle Seurin; Yves Le Bouc; Patrick C Even; Sylvie Babajko; C Magnan
Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain.
Diabetologia 2005;48(6):1189-97.
2005: Nathalie Bourcigaux; Gwenaëlle Arnault-Ouary; Rémy Christol; Laurence Périn; Bernard Charbonnel; Yves Le Bouc
Treatment of hypoglycemia using combined glucocorticoid and recombinant human growth hormone in a patient with a metastatic non-islet cell tumor hypoglycemia.
Clinical therapeutics 2005;27(2):246-51.
2004: Jet Bliek; Christine Gicquel; Saskia M Maas; Véronique Gaston; Yves Le Bouc; marcel mannens
Epigenotyping as a tool for the prediction of tumor risk and tumor type in patients with Beckwith-Wiedemann syndrome (BWS).
The Journal of pediatrics 2004;145(6):796-9.
2004: Géraldine Bienvenu; Danielle Seurin; Pascale Grellier; Pascal Froment; Marie Baudrimont; Philippe Monget; Yves Le Bouc; Sylvie Babajko
Insulin-like growth factor binding protein-6 transgenic mice: postnatal growth, brain development, and reproduction abnormalities.
Endocrinology 2004;145(5):2412-20.
2004: Christine Gicquel; J Weiss; J Amiel; Véronique Gaston; Yves Le Bouc; C D Scott
Epigenetic abnormalities of the mannose-6-phosphate/IGF2 receptor gene are uncommon in human overgrowth syndromes.
Journal of medical genetics 2004;41(1):e4.
2003: Maryvonne Laurent; Cécile Martinerie; Hélène Thibout; M P Hoffman; Franck Verrecchia; Yves Le Bouc; Alain Mauviel; H K Kleinman
NOVH increases MMP3 expression and cell migration in glioblastoma cells via a PDGFR-alpha-dependent mechanism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1919-21.
2003: Christine Gicquel; Véronique Gaston; Jacqueline Mandelbaum; Jean-Pierre Siffroi; Antoine Flahault; Yves Le Bouc
In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene.
American journal of human genetics 2003;72(5):1338-41.
2003: Marie-Hélène Bernard; Stan Sidhu; Nicole Berger; Jean-Louis Peix; Deborah J Marsh; Bruce G Robinson; Véronique Gaston; Yves Le Bouc; Christine Gicquel
A case report in favor of a multistep adrenocortical tumorigenesis.
The Journal of clinical endocrinology and metabolism 2003;88(3):998-1001.
2003: Martin Holzenberger; Joëlle Dupont; Bertrand Ducos; Patricia Leneuve; Alain Géloën; Patrick C Even; Pascale Cervera; Yves Le Bouc
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice.
Nature 2003;421(6919):182-7.
2003: Yves Le Bouc; Christine Gicquel; Martin Holzenberger
[Physiology of somatotropic axis: interest of gene inactivation experiments].
Bulletin de l'Académie nationale de médecine 2003;187(7):1225-43; discussion 1244-7.
2003: Hélène Thibout; Cécile Martinerie; C Créminon; F Godeau; P Boudou; Yves Le Bouc; Maryvonne Laurent
Characterization of human NOV in biological fluids: an enzyme immunoassay for the quantification of human NOV in sera from patients with diseases of the adrenal gland and of the nervous system.
The Journal of clinical endocrinology and metabolism 2003;88(1):327-36.
2002: Jérôme Lafont; Maryvonne Laurent; Hélène Thibout; François Lallemand; Yves Le Bouc; Azeddine Atfi; Cécile Martinerie
The expression of novH in adrenocortical cells is down-regulated by TGFbeta 1 through c-Jun in a Smad-independent manner.
The Journal of biological chemistry 2002;277(43):41220-9.
2002: Agathe Raynaud-Simon; Laurence Perin; Sylvie Meaume; B Lesourd; Robert Moulias; M C Postel-Vinay; Yves Le Bouc
IGF-I, IGF-I-binding proteins and GH-binding protein in malnourished elderly patients with inflammation receiving refeeding therapy.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(5):657-65.
2002: Valerie Besnard; Elodie Nabeyrat; Alexandra Henrion-Caude; Katarina Chadelat; Laurence Perin; Yves Le Bouc; Annick Clement
Protective role of retinoic acid from antiproliferative action of TNF-alpha on lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2002;282(4):L863-71.
2002: N Rich; Véronique Gaston; Yves Le Bouc; Christine Gicquel
Expression of the gene for the alpha-subunit of inhibin in human adrenocortical tumours.
Hormone research 2002;57(1-2):43-7.
2001: Patricia Leneuve; R Zaoui; P Monget; Yves Le Bouc; Martin Holzenberger
Genotyping of Cre-lox mice and detection of tissue-specific recombination by multiplex PCR.
BioTechniques 2001;31(5):1156-60, 1162.
2001: Bertrand Ducos; Sylvie Cabrol; Muriel Houang; Laurence Perin; Martin Holzenberger; Yves Le Bouc
IGF type 1 receptor ligand binding characteristics are altered in a subgroup of children with intrauterine growth retardation.
The Journal of clinical endocrinology and metabolism 2001;86(11):5516-24.
2001: Martin Holzenberger; Ghislaine Hamard; R Zaoui; Patricia Leneuve; Bertrand Ducos; C Beccavin; L Périn; Yves Le Bouc
Experimental IGF-I receptor deficiency generates a sexually dimorphic pattern of organ-specific growth deficits in mice, affecting fat tissue in particular.
Endocrinology 2001;142(10):4469-78.
2001: Christine Gicquel; Xavier Bertagna; Véronique Gaston; Joel Coste; Albert Louvel; Eric Baudin; Jérôme Bertherat; Yves Chapuis; J M Duclos; Martin Schlumberger; P F Plouin; Jean Pierre Luton; Yves Le Bouc
Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors.
Cancer research 2001;61(18):6762-7.
2001: Christophe Piketty; D Jayle; Alain Leplege; P Castiel; Emmanuel Ecosse; Gustavo Gonzalez-Canali; B Sabatier; N Boulle; B Debuire; Yves Le Bouc; Etienne Baulieu; Michel D Kazatchkine
Double-blind placebo-controlled trial of oral dehydroepiandrosterone in patients with advanced HIV disease.
Clinical endocrinology 2001;55(3):325-30.
2001: Cécile Martinerie; Christine Gicquel; Albert Louvel; Maryvonne Laurent; Paul N Schofield; Yves Le Bouc
Altered expression of novH is associated with human adrenocortical tumorigenesis.
The Journal of clinical endocrinology and metabolism 2001;86(8):3929-40.
2001: Agathe Raynaud-Simon; Sylviane Lafont; C Berr; Jean-François Dartigues; Etienne Baulieu; Yves Le Bouc
Plasma insulin-like growth factor I levels in the elderly: relation to plasma dehydroepiandrosterone sulfate levels, nutritional status, health and mortality.
Gerontology 2001;47(4):198-206.
2001: Véronique Gaston; Yves Le Bouc; Véronique Soupre; Lydie Burglen; jean donadieu; H Oro; Georges Audry; Marie-Paule Vazquez; Christine Gicquel
Analysis of the methylation status of the KCNQ1OT and H19 genes in leukocyte DNA for the diagnosis and prognosis of Beckwith-Wiedemann syndrome.
European journal of human genetics : EJHG 2001;9(6):409-18.
2001: Christine Gicquel; N Boulle; A Logié; Nathalie Bourcigaux; Véronique Gaston; Yves Le Bouc
[Involvement of the IGF system in the pathogenesis of adrenocortical tumors].
Annales d'endocrinologie 2001;62(2):189-92.
2001: sophie leboulleux; Véronique Gaston; N Boulle; Yves Le Bouc; Christine Gicquel
Loss of heterozygosity at the mannose 6-phosphate/insulin-like growth factor 2 receptor locus: a frequent but late event in adrenocortical tumorigenesis.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(2):163-8.
2001: N Boulle; Eric Baudin; Christine Gicquel; A Logié; Jérôme Bertherat; A Penfornis; Xavier Bertagna; Jean Pierre Luton; Martin Schlumberger; Yves Le Bouc
Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(1):29-36.
2000: Muriel Houang; Sylvie Cabrol; Laurence Perin; Bertrand Ducos; Albert Bensman; Yves Le Bouc
Insulin-like growth factor-I (IGF-I), insulin-like growth factor binding proteins (IGFBP) and insulin-like growth factor type I receptor in children with various status of chronic renal failure.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2000;10(6):332-41.
2000: A Logié; P Boudou; L Boccon-Gibod; Eric Baudin; G Vassal; Martin Schlumberger; Yves Le Bouc; Christine Gicquel
Establishment and characterization of a human adrenocortical carcinoma xenograft model.
Endocrinology 2000;141(9):3165-71.
2000: N Boulle; Christine Gicquel; A Logié; Rémy Christol; Jean-Jacques Feige; Yves Le Bouc
Fibroblast growth factor-2 inhibits the maturation of pro-insulin-like growth factor-II (Pro-IGF-II) and the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in the human adrenocortical tumor cell line NCI-H295R.
Endocrinology 2000;141(9):3127-36.
2000: Jérôme Bertherat; A Logié; Christine Gicquel; F Mourriéras; Jean Pierre Luton; Yves Le Bouc
Alterations of the 11p15 imprinted region and the IGFs system in a case of recurrent non-islet-cell tumour hypoglycaemia (NICTH).
Clinical endocrinology 2000;53(2):213-20.
2000: Martin Holzenberger; Patricia Leneuve; Ghislaine Hamard; Bertrand Ducos; Laurence Perin; Michel Binoux; Yves Le Bouc
A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficit.
Endocrinology 2000;141(7):2557-66.
2000: Etienne Baulieu; Gilles Thomas; Sylvie Legrain; Najiba Lahlou; M Roger; B Debuire; V Faucounau; L Girard; M P Hervy; Florence Latour; M C Leaud; A Mokrane; H Pitti-Ferrandi; Christophe Trivalle; O de Lacharrière; S Nouveau; B Rakoto-Arison; J C Souberbielle; J Raison; Yves Le Bouc; A Raynaud; X Girerd; Françoise Forette
Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4279-84.
2000: Claude Houdayer; Véronique Soupre; B Karcenty; Marie-Paule Vazquez; S Odent; D Lacombe; Yves Le Bouc; A Munnich; Michel Bahuau
1q32-q41 microdeletion with reference to Van der Woude syndrome and allied clefting entities.
American journal of medical genetics 2000;91(2):161-3.
2000: Christine Gicquel; Jérôme Bertherat; Yves Le Bouc; Xavier Bertagna
Pathogenesis of adrenocortical incidentalomas and genetic syndromes associated with adrenocortical neoplasms.
Endocrinology and metabolism clinics of North America 2000;29(1):1-13, vii.
2000: Martin Holzenberger; R Zaoui; Patricia Leneuve; Ghislaine Hamard; Yves Le Bouc
Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre).
Genesis (New York, N.Y. : 2000) 2000;26(2):157-9.
2000: Véronique Gaston; Yves Le Bouc; Véronique Soupre; Marie-Paule Vazquez; Christine Gicquel
Assessment of p57(KIP2) gene mutation in Beckwith-Wiedemann syndrome.
Hormone research 2000;54(1):1-5.
2000: Nathalie Bourcigaux; Véronique Gaston; A Logié; Xavier Bertagna; Yves Le Bouc; Christine Gicquel
High expression of cyclin E and G1 CDK and loss of function of p57KIP2 are involved in proliferation of malignant sporadic adrenocortical tumors.
The Journal of clinical endocrinology and metabolism 2000;85(1):322-30.
1999: Muriel Houang; Gilles Morineau; Yves Le Bouc; Jean Fiet; M Gourmelen
The cortisol-cortisone shuttle in children born with intrauterine growth retardation.
Pediatric research 1999;46(2):189-93.
1999: A Logié; N Boulle; Véronique Gaston; Laurence Perin; P Boudou; Yves Le Bouc; Christine Gicquel
Autocrine role of IGF-II in proliferation of human adrenocortical carcinoma NCI H295R cell line.
Journal of molecular endocrinology 1999;23(1):23-32.
1999: Béatrice Couzinet; Jacques Young; Sylvie Brailly; Yves Le Bouc; Philippe Chanson; Gilbert Schaison
Functional hypothalamic amenorrhoea: a partial and reversible gonadotrophin deficiency of nutritional origin.
Clinical endocrinology 1999;50(2):229-35.
1999: Claude Houdayer; Véronique Soupre; M Rosenberg-Bourgin; Hervé Martinez; Mohammed Tredano; Delphine Feldmann; J Feingold; P Aymard; A Munnich; Yves Le Bouc; Marie-Paule Vazquez; Michel Bahuau
Linkage analysis of 5 novel van der Woude syndrome kindreds to 1q32-q41 markers further supports locus homogeneity of the disease trait.
Annales de génétique 1999;42(2):69-74.
1998: J Boiko; Juliane Léger; MC Raux-Demay; Sylvie Cabrol; Yves Le Bouc; P Czernichow
[Basedow disease in children: clinical and evolutive aspects].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 1998;5(7):722-30.
1998: James Lespinasse; Christine Gicquel; M Robert; Yves Le Bouc
Phenotypic and genotypic variability in monozygotic triplets with Turner syndrome.
Clinical genetics 1998;54(1):56-9.
1998: N Boulle; A Logié; Christine Gicquel; Laurence Perin; Yves Le Bouc
Increased levels of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 are associated with malignancy in sporadic adrenocortical tumors.
The Journal of clinical endocrinology and metabolism 1998;83(5):1713-20.
1998: Christine Gicquel; Véronique Gaston; Sylvie Cabrol; Yves Le Bouc
Assessment of Turner's syndrome by molecular analysis of the X chromosome in growth-retarded girls.
The Journal of clinical endocrinology and metabolism 1998;83(5):1472-6.
1998: Sylvie Cabrol; Muriel Houang; Yves Le Bouc
[Physiopathology of the somatotropin axis in chronic renal insufficiency].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 1998;5 Suppl 4():348S-353S.
1997: Yves Le Bouc; Agnès Bellocq; C Philippe; Laurence Perin; M Garabedian; Bruno Fouqueray; C Zacharias; Jacques Cadranel; Laurent Baud
Insulin-like growth factors and their binding proteins in pleural fluid.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(5):467-73.
1997: Christine Gicquel; Marie-Laure Raffin-Sanson; Véronique Gaston; Xavier Bertagna; P F Plouin; Martin Schlumberger; Albert Louvel; Jean Pierre Luton; Yves Le Bouc
Structural and functional abnormalities at 11p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: study on a series of 82 tumors.
The Journal of clinical endocrinology and metabolism 1997;82(8):2559-65.
1997: H Schneid; Marie-Paule Vazquez; C Vacher; M Gourmelen; Sylvie Cabrol; Yves Le Bouc
The Beckwith-Wiedemann syndrome phenotype and the risk of cancer.
Medical and pediatric oncology 1997;28(6):411-5.
1997: Christine Gicquel; Yves Le Bouc
Molecular markers for malignancy in adrenocortical tumors.
Hormone research 1997;47(4-6):269-72.
1996: Nicolas de Roux; Micheline Misrahi; R Brauner; Muriel Houang; J C Carel; M Granier; Yves Le Bouc; Nicolae Ghinea; A Boumedienne; J E Toublanc; Edwin Milgrom
Four families with loss of function mutations of the thyrotropin receptor.
The Journal of clinical endocrinology and metabolism 1996;81(12):4229-35.
1996: Sylvie Cabrol; C Saab; M Gourmelen; M C Raux-Demay; Yves Le Bouc
[Turner syndrome: spontaneous growth of stature, weight increase and accelerated bone maturation].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 1996;3(4):313-8.
1996: Yves Le Bouc; Laurence Perin; Sylvie Cabrol; M Gourmelen
[IGF-I and its regulation system].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 1996;3 Suppl 1():141s-143s.
1995: Wolf Reik; K W Brown; H Schneid; Yves Le Bouc; W Bickmore; E R Maher
Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by altered imprinting pattern in the IGF2-H19 domain.
Human molecular genetics 1995;4(12):2379-85.
1995: Christine Gicquel; A Dib; Xavier Bertagna; S Amselem; Yves Le Bouc
Oncogenic mutations of alpha-Gi2 protein are not determinant for human adrenocortical tumourigenesis.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(2):166-72.
1995: Christine Gicquel; Xavier Bertagna; Yves Le Bouc
Recent advances in the pathogenesis of adrenocortical tumours.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(2):133-44.
1995: Christine Gicquel; Yves Le Bouc
[Insulin-like growth factor II (IGF II) and adrenocortical tumorigenesis].
Annales d'endocrinologie 1995;56(6):617-8.
1995: Pierre Rochiccioli; J Battin; Anne-Marie Bertrand; M Bost; Sylvie Cabrol; Yves Le Bouc; Jean-Louis Chaussain; P Chatelain; M Colle; Paul Czernichow
Final height in Turner syndrome patients treated with growth hormone.
Hormone research 1995;44(4):172-6.
1995: Yves Le Bouc
[Insulin-like growth factors (IGF) and their binding proteins (IGFBP). Physiological and pathological regulation].
Journées annuelles de diabétologie de l'Hôtel-Dieu 1995;():29-38.
1994: Christine Gicquel; Xavier Bertagna; H Schneid; M Francillard-Leblond; Jean Pierre Luton; F Girard; Yves Le Bouc
Rearrangements at the 11p15 locus and overexpression of insulin-like growth factor-II gene in sporadic adrenocortical tumors.
The Journal of clinical endocrinology and metabolism 1994;78(6):1444-53.
1994: M Gourmelen; Laurence Perin; Yves Le Bouc
IGFs and their binding proteins.
Nuclear medicine and biology 1994;21(3):297-302.
1994: Christine Gicquel; M Leblond-Francillard; Xavier Bertagna; A Louvel; Y Chapuis; Jean Pierre Luton; F Girard; Yves Le Bouc
Clonal analysis of human adrenocortical carcinomas and secreting adenomas.
Clinical endocrinology 1994;40(4):465-77.
1994: P Rocchiccioli; J Battin; Anne-Marie Bertrand; M Bost; Sylvie Cabrol; Yves Le Bouc; Jean-Louis Chaussain; P Chatelain; J C Job; B Leheup
[Final height in Turner syndrome treated with growth hormone].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 1994;1(4):359-62.
1994: C Vacher; Marie-Paule Vazquez; Yves Le Bouc; H Schneid
[Wiedemann-Beckwith syndrome: apropos of 20 cases].
Revue de stomatologie et de chirurgie maxillo-faciale 1994;95(2):192-3.
1993: H Schneid; D Seurin; Marie-Paule Vazquez; M Gourmelen; Sylvie Cabrol; Yves Le Bouc
Parental allele specific methylation of the human insulin-like growth factor II gene and Beckwith-Wiedemann syndrome.
Journal of medical genetics 1993;30(5):353-62.
1992: Christine Gicquel; Sylvie Cabrol; H Schneid; F Girard; Yves Le Bouc
Molecular diagnosis of Turner's syndrome.
Journal of medical genetics 1992;29(8):547-51.
1992: Christine Gicquel; Yves Le Bouc; Jean Pierre Luton; F Girard; Xavier Bertagna
Monoclonality of corticotroph macroadenomas in Cushing's disease.
The Journal of clinical endocrinology and metabolism 1992;75(2):472-5.
1992: H Schneid; D Seurin; P Noguiez; Yves Le Bouc
Abnormalities of insulin-like growth factor (IGF-I and IGF-II) genes in human tumor tissue.
Growth regulation 1992;2(1):45-54.
1991: H Schneid; Marie-Paule Vazquez; D Seurin; Yves Le Bouc
Loss of heterozygosity in non-tumoral tissue in two children with Beckwith-Wiedemann syndrome.
Growth regulation 1991;1(4):168-70.
1991: H Schneid; D Seurin; Yves Le Bouc
[Pathology of the growth and abnormalities of IGF genes].
Annales d'endocrinologie 1991;52(6):479-82.
1990: H Schneid; Yves Le Bouc; D Seurin; M Gourmelen; Sylvie Cabrol; M C Raux-Demay; F Girard; Michel Binoux
Insulin-like growth factor-I gene analysis in subjects with constitutionally variant stature.
Pediatric research 1990;27(5):488-91.
1989: S Hardouin; M Gourmelen; P Noguiez; D Seurin; M Roghani; Yves Le Bouc; G Povoa; T J Merimee; P Hossenlopp; Michel Binoux
Molecular forms of serum insulin-like growth factor (IGF)-binding proteins in man: relationships with growth hormone and IGFs and physiological significance.
The Journal of clinical endocrinology and metabolism 1989;69(6):1291-301.
1989: H Schneid; F Girard; Michel Binoux; Yves Le Bouc
Ava II RFLP at the insulin-like growth factor II (IGF II) locus on chromosome 11.
Nucleic acids research 1989;17(1):466.
1988: H Schneid; P Noguiez; F Girard; Michel Binoux; Yves Le Bouc
Eco RV RFLP at the insulin-like growth factor I (IGF I) locus on chromosome 12.
Nucleic acids research 1988;16(18):9059.
1988: Yves Le Bouc
[Regulation of the biosynthesis of insulin-like growth factors and variation in the expression of their genes].
Annales d'endocrinologie 1988;49(4-5):315-8.
1987: Yves Le Bouc; P Noguiez; P Sondermeijer; D Dreyer; F Girard; Michel Binoux
A new 5'-non-coding region for human placental insulin-like growth factor II mRNA expression.
FEBS letters 1987;222(1):181-5.
1986: Yves Le Bouc; D Dreyer; F Jaeger; Michel Binoux; P Sondermeyer
Complete characterization of the human IGF-I nucleotide sequence isolated from a newly constructed adult liver cDNA library.
FEBS letters 1986;196(1):108-12.
1984: M Gourmelen; Yves Le Bouc; F Girard; Michel Binoux
Serum levels of insulin-like growth factor (IGF) and IGF binding protein in constitutionally tall children and adolescents.
The Journal of clinical endocrinology and metabolism 1984;59(6):1197-203.