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Jacques Le Bras

Research Profile

Chemicals & Drugs

Physiology

Drug Resistance

Disorders

Geographic Areas

Activities & Behaviors

Travel

Procedures

Parasitic Sensitivity Tests

Living Beings

Infants

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Publications

TOP 3
Myriam Gharbi; Philippe J Guérin; Véronique Hubert; Eric Kendjo; Jacques Le Bras; Jessica E Metcalf; Ahmed Aboubaca; Patrice Agnamey; Muriel Mimoun Aiach; Adela Angoulvant; Patricia Barbut; Didier Basset; Ghania Belkadi; Anne Pauline Bellanger; Dieudonné Bemba; Françoise Benoit-Vica; Antoine Berry; Marie-Laure Bigel; Julie Bonhomme; Françoise Botterel; Olivier Bouchaud; Marie-Elisabeth Bougnoux; Patrice Bourée; Nathalie Bourgeois; Catherine Branger; Laurent Bret; Bernadette Buret; Enrique Casalino; Sylviane Chevrier; Frédérique Conquere de Monbrison; Bernadette Cuisenier; Martin Danis; Marie-Laure Darde; Ludovic De Gentile; Jean-Marie Delarbre; Pascal Delaunay; Anne Delaval; Guillaume Desoubeaux; Michel Develoux; Jean Dunand; Rémy Durand; Odile Eloy; Nathalie Fauchet; Bernard Faugere; Alber Faye; Odile Fenneteau; Pierre Flori; Madeleine Fontrouge; Chantal Garabedian; Françoise Gayandrieu; Nadine Godineau; Pascal Houzé; Sandrine Houzé; Jean-Pierre Hurst; Houria Ichou; Laurence Lachaud; Gwenaë Le Moal; Agathe Lebuisson; Magalie Lefevre; Anne-Sophie LeGuern; Daniel Lusina; Marie-Claude Machouart; Denis Malvy; Sophie Matheron; Danièle Maubon; Denis Mechali; Bruno Megarbane; Guillaume Menard; Laurence Millon; Philippe Minodier; Christelle Morelle; Gilles Nevez; Philippe Parola; Daniel Parzy; Olivier Patey; Pierre Patoz; Pascale Penn; Alice Perignon; Stéphane Picot; Jean-Etienne Pilo; Isabelle Poilane; Denis Pons; Marie Poupart; Bruno Pradines; Didier Raffenot; Christophe Rapp; Marie-Catherine Receveur; Claudine Sarfati; Yaye Senghor; Fabrice Simon; Jean-Yves Siriez; Nicolas Taudon; Marc Thellier; Maxime Thouvenin; Lionel Bertaux; Jennifer A Flegg; Dominique Toubas
Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000-2011.
Sandrine Cojean; Djamel Haouchine; Sandrine Houzé; Véronique Hubert; Françoise Huteau; Sylvie Lariven; Jacques Le Bras; Philippe Marie Loiseau; Florence Michard; Francine Pratlong; Christian Bories; Sophie Matheron
Leishmania resistance to miltefosine associated with genetic marker.
Sandrine Houzé; Véronique Hubert; Jacques Le Bras; Gaëlle Le Pessec; Jérôme Clain
Combined deletions of pfhrp2 and pfhrp3 genes result in Plasmodium falciparum malaria false-negative rapid diagnostic test.

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All Publications

2013: Myriam Gharbi; Philippe J Guérin; Véronique Hubert; Eric Kendjo; Jacques Le Bras; Jessica E Metcalf; Ahmed Aboubaca; Patrice Agnamey; Muriel Mimoun Aiach; Adela Angoulvant; Patricia Barbut; Didier Basset; Ghania Belkadi; Anne Pauline Bellanger; Dieudonné Bemba; Françoise Benoit-Vica; Antoine Berry; Marie-Laure Bigel; Julie Bonhomme; Françoise Botterel; Olivier Bouchaud; Marie-Elisabeth Bougnoux; Patrice Bourée; Nathalie Bourgeois; Catherine Branger; Laurent Bret; Bernadette Buret; Enrique Casalino; Sylviane Chevrier; Frédérique Conquere de Monbrison; Bernadette Cuisenier; Martin Danis; Marie-Laure Darde; Ludovic De Gentile; Jean-Marie Delarbre; Pascal Delaunay; Anne Delaval; Guillaume Desoubeaux; Michel Develoux; Jean Dunand; Rémy Durand; Odile Eloy; Nathalie Fauchet; Bernard Faugere; Alber Faye; Odile Fenneteau; Pierre Flori; Madeleine Fontrouge; Chantal Garabedian; Françoise Gayandrieu; Nadine Godineau; Pascal Houzé; Sandrine Houzé; Jean-Pierre Hurst; Houria Ichou; Laurence Lachaud; Gwenaë Le Moal; Agathe Lebuisson; Magalie Lefevre; Anne-Sophie LeGuern; Daniel Lusina; Marie-Claude Machouart; Denis Malvy; Sophie Matheron; Danièle Maubon; Denis Mechali; Bruno Megarbane; Guillaume Menard; Laurence Millon; Philippe Minodier; Christelle Morelle; Gilles Nevez; Philippe Parola; Daniel Parzy; Olivier Patey; Pierre Patoz; Pascale Penn; Alice Perignon; Stéphane Picot; Jean-Etienne Pilo; Isabelle Poilane; Denis Pons; Marie Poupart; Bruno Pradines; Didier Raffenot; Christophe Rapp; Marie-Catherine Receveur; Claudine Sarfati; Yaye Senghor; Fabrice Simon; Jean-Yves Siriez; Nicolas Taudon; Marc Thellier; Maxime Thouvenin; Lionel Bertaux; Jennifer A Flegg; Dominique Toubas
Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000-2011.
Malaria journal 2013;12(1):35.
2012: Sandrine Cojean; Djamel Haouchine; Sandrine Houzé; Véronique Hubert; Françoise Huteau; Sylvie Lariven; Jacques Le Bras; Philippe Marie Loiseau; Florence Michard; Francine Pratlong; Christian Bories; Sophie Matheron
Leishmania resistance to miltefosine associated with genetic marker.
Emerging infectious diseases 2012;18(4):704-6.
2011: Sandrine Houzé; Véronique Hubert; Jacques Le Bras; Gaëlle Le Pessec; Jérôme Clain
Combined deletions of pfhrp2 and pfhrp3 genes result in Plasmodium falciparum malaria false-negative rapid diagnostic test.
Journal of clinical microbiology 2011;49(7):2694-6.
2011: Ronan Jambou; Jacques Le Bras; Milijaona Randrianarivelojosia
Pitfalls in new artemisinin-containing antimalarial drug development.
Trends in parasitology 2011;27(2):82-90.
2011: Sandrine Houzé; Véronique Hubert; Dorit Pessler Cohen; Baruch Rivetz; Jacques Le Bras
Evaluation of the Clearview® Malaria pLDH Malaria Rapid Diagnostic Test in a non-endemic setting.
Malaria journal 2011;10():284.
2010: Oumou Maïga-Ascofaré; Jacques Le Bras; Rabia Mazmouz; Emmanuelle Renard; Sarah Falcão; Emeline Broussier; Dorina Bustos; Milijaona Randrianarivelojosia; Sabah A Omar; Agnès Aubouy; Jean-François Lepère; Vély Jean-François; Abdoulaye A Djimdé; Jérôme Clain
Adaptive differentiation of Plasmodium falciparum populations inferred from single-nucleotide polymorphisms (SNPs) conferring drug resistance and from neutral SNPs.
The Journal of infectious diseases 2010;202(7):1095-103.
2009: Sandrine Houzé; Mainoumata Dicko Boly; Jacques Le Bras; Philippe Deloron; Jean-François Faucher
PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria.
Malaria journal 2009;8():211.
2008: Rémy Durand; Frédéric Ariey; Sandrine Cojean; Arnaud Fontanet; Louise Ranaivo; Lanto-Alisoa Ranarivelo; Jeanne Aimée Vonimpaisomihanta; Didier Menard; Virginio Pietra; Jacques Le Bras; David Modiano; Milijaona Randrianarivelojosia
Analysis of circulating populations of Plasmodium falciparum in mild and severe malaria in two different epidemiological patterns in Madagascar.
Tropical medicine & international health : TM & IH 2008;13(11):1392-9.
2008: S Cojean; S Jafari-Guemouri; Jacques Le Bras; Rémy Durand
Cytoadherence characteristics to endothelial receptors ICAM-1 and CD36 of Plasmodium falciparum populations from severe and uncomplicated malaria cases.
Parasite (Paris, France) 2008;15(2):163-9.
2008: Halima Kaddouri; Abdoulaye Djimdé; Souleymane Dama; Aly Kodio; Mamadou Tekete; Véronique Hubert; Aminatou Koné; Hamma Maiga; Oumar Yattara; Bakary Fofana; Bakary Sidibe; Cheick P O Sangaré; Ogobara K Doumbo; Jacques Le Bras
Baseline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali.
International journal for parasitology 2008;38(7):791-8.
2008: Eric D'Ortenzio; Nadine Godineau; Arnaud Fontanet; Sandrine Houze; Olivier Bouchaud; Sophie Matheron; Jacques Le Bras
Prolonged Plasmodium falciparum infection in immigrants, Paris.
Emerging infectious diseases 2008;14(2):323-6.
2008: Rémy Durand; Virginie Prendki; Johann Cailhol; Véronique Hubert; Pascal Ralaimazava; Laurent Massias; Olivier Bouchaud; Jacques Le Bras
Plasmodium falciparum malaria and atovaquone-proguanil treatment failure.
Emerging infectious diseases 2008;14(2):320-2.
2008: Basile Nsimba; Vincent Guiyedi; Modeste Mabika-Mamfoumbi; Jean Romain Mourou-Mbina; Edgard Ngoungou; Marielle Bouyou-Akotet; Romaric Loembet; Rémy Durand; Jacques Le Bras; Maryvonne Kombila
Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: a randomized trial to guide national policy.
Malaria journal 2008;7():31.
2007: Rémy Durand; Jacques Le Bras; Olivier Bouchaud
[Is chloroquine back?].
La Revue du praticien 2007;57(14):1513-5.
2007: Valérie Briand; Olivier Bouchaud; Jérôme Tourret; Charlotte Behr; Sophie Abgrall; Pascal Ralaimazava; Jacques Le Bras; Arnaud Fontanet
Hospitalization criteria in imported falciparum malaria.
Journal of travel medicine 2007;14(5):306-11.
2007: Sandrine Houzé; Aline Munier; Xavier Paoletti; Halima Kaddouri; Pascal Ringwald; Jacques Le Bras
Shelf life of predosed plates containing mefloquine, artemisinin, dihydroartemisinin, and artesunate as used for in vitro Plasmodium falciparum susceptibility assessment.
Journal of clinical microbiology 2007;45(8):2734-6.
2007: Lise Musset; Jacques Le Bras; Jérôme Clain
Parallel evolution of adaptive mutations in Plasmodium falciparum mitochondrial DNA during atovaquone-proguanil treatment.
Molecular biology and evolution 2007;24(8):1582-5.
2007: Fabrice Legros; Olivier Bouchaud; Thierry Ancelle; Amandine Arnaud; Sandrine Cojean; Jacques Le Bras; Martin Danis; Arnaud Fontanet; Rémy Durand
Risk factors for imported fatal Plasmodium falciparum malaria, France, 1996-2003.
Emerging infectious diseases 2007;13(6):883-8.
2007: Delphine Lejeune; Isabelle Souletie; Sandrine Houzé; thierry le bricon; Jacques Le Bras; Bernard Gourmel; Pascal Houzé
Simultaneous determination of monodesethylchloroquine, chloroquine, cycloguanil and proguanil on dried blood spots by reverse-phase liquid chromatography.
Journal of pharmaceutical and biomedical analysis 2007;43(3):1106-15.
2007: Arthur M Talman; Linda Duval; Eric Legrand; Véronique Hubert; Seiha Yen; David Bell; Jacques Le Bras; Frédéric Ariey; Sandrine Houze
Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase.
Malaria journal 2007;6():140.
2007: David J Bacon; Ronan Jambou; Thierry Fandeur; Jacques Le Bras; Chansuda Wongsrichanalai; Mark M Fukuda; Pascal Ringwald; Carol Hopkins Sibley; Dennis E Kyle
World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility.
Malaria journal 2007;6():120.
2007: Nitchakarn Noranate; Rémy Durand; Adama Tall; Laurence Marrama; André Spiegel; Cheikh Sokhna; Bruno Pradines; Sandrine Cojean; Micheline Guillotte; Emmanuel Bischoff; Marie-Thérèse Ekala; Christiane Bouchier; Thierry Fandeur; Frédéric Ariey; Jintana Patarapotikul; Jacques Le Bras; Jean-François Trape; Christophe Rogier; Odile Mercereau-Puijalon
Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use.
PloS one 2007;2(1):e139.
2006: Sandrine Cojean; Véronique Hubert; Jacques Le Bras; Rémy Durand
Resistance to dihydroartemisinin.
Emerging infectious diseases 2006;12(11):1798-9.
2006: Halima Kaddouri; Serge Nakache; Sandrine Houzé; France Mentré; Jacques Le Bras
Assessment of the drug susceptibility of Plasmodium falciparum clinical isolates from africa by using a Plasmodium lactate dehydrogenase immunodetection assay and an inhibitory maximum effect model for precise measurement of the 50-percent inhibitory concentration.
Antimicrobial agents and chemotherapy 2006;50(10):3343-9.
2006: Lise Musset; Olivier Bouchaud; Sophie Matheron; Laurent Massias; Jacques Le Bras
Clinical atovaquone-proguanil resistance of Plasmodium falciparum associated with cytochrome b codon 268 mutations.
Microbes and infection / Institut Pasteur 2006;8(11):2599-604.
2006: Jacques Le Bras; Lise Musset; Jérôme Clain
[Antimalarial drug resistance].
Médecine et maladies infectieuses 2006;36(8):401-5.
2006: Frédéric Ariey; Thierry Fandeur; Rémy Durand; Milijaona Randrianarivelojosia; Ronan Jambou; Eric Legrand; Marie-Thérèse Ekala; Christiane Bouchier; Sandrine Cojean; Jean-Bernard Duchemin; Vincent Robert; Jacques Le Bras; Odile Mercereau-Puijalon
Invasion of Africa by a single pfcrt allele of South East Asian type.
Malaria journal 2006;5():34.
2006: Léon P Rabarijaona; Frédéric Ariey; Robert Matra; Sylvie Cot; Andrianavalona Lucie Raharimalala; Louise Henriette Ranaivo; Jacques Le Bras; Vincent Robert; Milijaona Randrianarivelojosia
Low autochtonous urban malaria in Antananarivo (Madagascar).
Malaria journal 2006;5():27.
2006: Sandrine Cojean; Alain Noël; Dimitri Garnier; Véronique Hubert; Jacques Le Bras; Rémy Durand
Lack of association between putative transporter gene polymorphisms in Plasmodium falciparum and chloroquine resistance in imported malaria isolates from Africa.
Malaria journal 2006;5():24.
2006: Lise Musset; Bruno Pradines; Daniel Parzy; Rémy Durand; Patricia Bigot; Jacques Le Bras
Apparent absence of atovaquone/proguanil resistance in 477 Plasmodium falciparum isolates from untreated French travellers.
The Journal of antimicrobial chemotherapy 2006;57(1):110-5.
2005: Arnaud Fontanet; Sandrine Houzé; Annick Keundjian; Ricarda Schiemann; Pascal Ralaimazava; Rémy Durand; Olivier Cha; Jean-Pierre Coulaud; Jacques Le Bras; Olivier Bouchaud
Efficacy of antimalarial chemoprophylaxis among French residents travelling to Africa.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2005;99(2):91-100.
2005: Olivier Bouchaud; Michel Cot; Sabine Kony; Rémy Durand; Ricarda Schiemann; Pascal Ralaimazava; Jean-Pierre Coulaud; Jacques Le Bras; Philippe Deloron
Do African immigrants living in France have long-term malarial immunity?
The American journal of tropical medicine and hygiene 2005;72(1):21-5.
2004: Agnès Aubouy; Justice Mayombo; Annick Keundjian; Mohamed Bakary; Jacques Le Bras; Philippe Deloron
Short report: lack of prediction of amodiaquine efficacy in treating Plasmodium falciparum malaria by in vitro tests.
The American journal of tropical medicine and hygiene 2004;71(3):294-6.
2004: Sayeh Jafari; Jacques Le Bras; Olivier Bouchaud; Rémy Durand
Plasmodium falciparum clonal population dynamics during malaria treatment.
The Journal of infectious diseases 2004;189(2):195-203.
2004: Halima Kaddouri; Sayeh Jafari; Rémy Durand; Jacques Le Bras
[Drug susceptibility of Plasmodium falciparum from polyclonal isolates].
Journal de la Société de biologie 2004;198(3):199-206.
2003: Agnès Aubouy; Sayeh Jafari; Virginie Huart; Florence Migot-Nabias; Justice Mayombo; Rémy Durand; Mohamed Bakary; Jacques Le Bras; Philippe Deloron
DHFR and DHPS genotypes of Plasmodium falciparum isolates from Gabon correlate with in vitro activity of pyrimethamine and cycloguanil, but not with sulfadoxine-pyrimethamine treatment efficacy.
The Journal of antimicrobial chemotherapy 2003;52(1):43-9.
2003: Pascal Ralaimazava; Olivier Bouchaud; Nadine Godineau; S Hamane; Annick Keundjian; Rémy Durand; Jacques Le Bras
[Imported malaria in 2000 in 2 northern Paris hospitals].
Bulletin de la Société de pathologie exotique (1990) 2003;96(2):119-22.
2003: Jacques Le Bras; Rémy Durand
The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum.
Fundamental & clinical pharmacology 2003;17(2):147-53.
2003: Sayeh Jafari; Jacques Le Bras; M Asmar; Rémy Durand
Molecular survey of Plasmodium falciparum resistance in south-eastern Iran.
Annals of tropical medicine and parasitology 2003;97(2):119-24.
2003: Fabrice Bruneel; Laurent Hocqueloux; Corinne Alberti; Michel Wolff; Sylvie Chevret; Jean-Pierre Bédos; Rémy Durand; Jacques Le Bras; Bernard Régnier; François Vachon
The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults.
American journal of respiratory and critical care medicine 2003;167(5):684-9.
2003: Agnès Aubouy; Mohamed Bakary; Annick Keundjian; Bernard Mbomat; Jean Ruffin Makita; Florence Migot-Nabias; Michel Cot; Jacques Le Bras; Philippe Deloron
Combination of drug level measurement and parasite genotyping data for improved assessment of amodiaquine and sulfadoxine-pyrimethamine efficacies in treating Plasmodium falciparum malaria in Gabonese children.
Antimicrobial agents and chemotherapy 2003;47(1):231-7.
2002: Jean Marc Roussin; Virginie Huart; Jean François Lepère; Marie Jo Le Bras; Céline Roussin; Jacques Le Bras
[Rapid detection of malaria and P. falciparum chemoresistant genotypes in Mayotte, 2001].
Presse médicale (Paris, France : 1983) 2002;31(28):1312.
2002: Rémy Durand; Virginie Huart; Sayeh Jafari; Jacques Le Bras
Rapid detection of a molecular marker for chloroquine-resistant falciparum malaria.
Antimicrobial agents and chemotherapy 2002;46(8):2684-6.
2002: Pascal Ralaimazava; Rémy Durand; Nadine Godineau; Annick Keundjian; Z Jezic; Bruno Pradines; Olivier Bouchaud; Jacques Le Bras
Profile and evolution of the chemosusceptibility of falciparum malaria imported into France in 2000.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2002;7(7):113-8.
2002: Sayeh Jafari; Rémy Durand; D Lusina; Jacques Le Bras
Molecular characterisation of airport malaria: four cases in France during summer 1999.
Parasite (Paris, France) 2002;9(2):187-91.
2001: Rémy Durand; Sayeh Jafari; Olivier Bouchaud; Pascal Ralaimazava; Annick Keundjian; Jacques Le Bras
Plasmodium falciparum: pfcrt and DHFR mutations are associated with failure of chloroquine plus proguanil prophylaxis in travelers.
The Journal of infectious diseases 2001;184(12):1633-4.
2001: Rémy Durand; Jacques Le Bras
[Plasmodium falciparum: point mutations of pcfrt and chloroquine susceptibility].
Annales pharmaceutiques françaises 2001;59(5):312-8.
2001: Rémy Durand; Sayeh Jafari; J Vauzelle; JF Delabre; Z Jesic; Jacques Le Bras
Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum.
Molecular and biochemical parasitology 2001;114(1):95-102.
2001: C Giverne; Fabrice Bruneel; Bertrand Gachot; R Durand; Jacques Le Bras
[Treatment of acute malaria with quinine in a non-immunized patient: rationale for a 7-day regimen].
Presse médicale (Paris, France : 1983) 2001;30(10):488-9.
2000: Rémy Durand; J Eslahpazire; Sayeh Jafari; JF Delabre; A Marmorat-Khuong; JP di Piazza; Jacques Le Bras
Use of molecular beacons to detect an antifolate resistance-associated mutation in Plasmodium falciparum.
Antimicrobial agents and chemotherapy 2000;44(12):3461-4.
2000: Olivier Bouchaud; E Monlun; K Muanza; Arnaud Fontanet; T Scott; A Goetschel; J D Chulay; Jacques Le Bras; Martin Danis; M Le Bras; Jean-Pierre Coulaud; M Gentilini
Atovaquone plus proguanil versus halofantrine for the treatment of imported acute uncomplicated Plasmodium falciparum malaria in non-immune adults: a randomized comparative trial.
The American journal of tropical medicine and hygiene 2000;63(5-6):274-9.
2000: Olivier Bouchaud; Sandrine Houzé; C Longuet; JP di Piazza; C Ruggieri; Y Sécardin; Jean-Pierre Coulaud; Jacques Le Bras
Use of the Parasight-F diagnostic test for imported malaria in a travel clinic.
The American journal of tropical medicine and hygiene 2000;63(1-2):76-9.
1999: Jacques Le Bras
[Mechanisms and dynamics of drug resistance in Plasmodium falciparum].
Bulletin de la Société de pathologie exotique (1990) 1999;92(4):236-41.
1999: Rémy Durand; E Gabbett; JP di Piazza; JF Delabre; Jacques Le Bras
Analysis of kappa and omega repeats of the cg2 gene and chloroquine susceptibility in isolates of Plasmodium falciparum from sub-Saharan Africa.
Molecular and biochemical parasitology 1999;101(1-2):185-97.
1999: Y Secardin; Jacques Le Bras
[Diagnostic test to identify human Plasmodium species by the quantitative buffy coat test].
Médecine tropicale : revue du Corps de santé colonial 1999;59(3):276-8.
1999: Rémy Durand; JP di Piazza; C Longuet; Y Sécardin; J Clain; Jacques Le Bras
Increased incidence of cycloguanil resistance in malaria cases entering France from Africa, determined as point mutations in the parasites' dihydrofolate-reductase genes.
Annals of tropical medicine and parasitology 1999;93(1):25-30.
1998: Jacques Le Bras; Rémy Durand; JP di Piazza; Bruno Pradines; C Longuet; D Parzy
[Considering disparities in resistance of Plasmodium falciparum in Africa in chemoprevention decisions].
Presse médicale (Paris, France : 1983) 1998;27(28):1419-23.
1998: C Longuet; Olivier Bouchaud; Jacques Le Bras; Jean-Pierre Coulaud
[Plasmodium falciparum malaria: type R1 resistance to quinine in west Africa].
Presse médicale (Paris, France : 1983) 1998;27(11):522.
1998: Jacques Le Bras; C Longuet; G Charmot
[Human transmission and plasmodium resistance].
La Revue du praticien 1998;48(3):258-63.
1998: Jacques Le Bras
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu.
Médecine tropicale : revue du Corps de santé colonial 1998;58(3 Suppl):18-21.
1998: Jacques Le Bras; Bruno Pradines; JP di Piazza; Rémy Durand; Nadine Godineau; Olivier Bouchaud; R Roué; B Marchou; G Martet; C Longuet; D Parzy
[Resistance to chloroquine and cycloguanil of Plasmodium falciparum in patients arriving in France after travel in Africa without chemoprophylaxis].
Bulletin de la Société de pathologie exotique (1990) 1998;91(5 Pt 1-2):490-2.
1997: Rémy Durand; O Ramiliarisoa; Y Sécardin; P Eldin de Pécoulas; L K Basco; Jacques Le Bras
DHFR gene point mutation as a predictor of Plasmodium falciparum resistance to cycloguanil in malaria cases from Africa imported to France.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(4):460-1.
1997: J Clain; G Peytavin; Bertrand Gachot; François Vachon; Jacques Le Bras
[Optimum quinine therapy in falciparum malaria attacks contracted in Africa].
Bulletin de la Société de pathologie exotique (1990) 1997;90(4):260-2.
1997: C Longuet; O Ramiliarisoa; R Thor; Olivier Bouchaud; L K Basco; J C Doury; Jacques Le Bras
[Drug sensitivity of falciparum malaria imported into France in 1995].
Bulletin de la Société de pathologie exotique (1990) 1997;90(4):253-6.
1997: L K Basco; Jacques Le Bras
In vitro sensitivity of Plasmodium falciparum to anti-folinic agents (trimethoprim, pyrimethamine, cycloguanil): a study of 29 African strains.
Bulletin de la Société de pathologie exotique (1990) 1997;90(2):90-3.
1996: B Pradines; Florence Ramiandrasoa; Leonardo K Basco; L Bricard; Gerhard Kunesch; Jacques Le Bras
In vitro activities of novel catecholate siderophores against Plasmodium falciparum.
Antimicrobial agents and chemotherapy 1996;40(9):2094-8.
1996: Philippe Eldin de Pécoulas; Leonardo K Basco; Jacques Le Bras; André Mazabraud
Association between antifol resistance in vitro and DHFR gene point mutation in Plasmodium falciparum isolates.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1996;90(2):181-2.
1996: Leonardo K Basco; Philippe Eldin de Pécoulas; Jacques Le Bras; C M Wilson
Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates.
Experimental parasitology 1996;82(2):97-103.
1996: Jacques Le Bras; Leonardo K Basco; Philippe Eldin de Pécoulas
[Mechanisms and epidemiology of resistances to antimalarials].
Comptes rendus des séances de la Société de biologie et de ses filiales 1996;190(4):471-85.
1995: Philippe Eldin de Pécoulas; B Abdallah; M K Dje; Leonardo K Basco; Jacques Le Bras; André Mazabraud
Use of a semi-nested PCR diagnosis test to evaluate antifolate resistance of Plasmodium falciparum isolates.
Molecular and cellular probes 1995;9(6):391-7.
1995: Leonardo K Basco; Jacques Le Bras; Z Rhoades; C M Wilson
Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from subsaharan Africa.
Molecular and biochemical parasitology 1995;74(2):157-66.
1995: Leonardo K Basco; P Ringwald; R Thor; J C Doury; Jacques Le Bras
Activity in vitro of chloroquine, cycloguanil, and mefloquine against African isolates of Plasmodium falciparum: presumptive evidence for chemoprophylactic efficacy in Central and West Africa.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1995;89(6):657-8.
1995: Leonardo K Basco; O Ramiliarisoa; Jacques Le Bras
In vitro activity of atovaquone against the African isolates and clones of Plasmodium falciparum.
The American journal of tropical medicine and hygiene 1995;53(4):388-91.
1995: G Cremer; Leonardo K Basco; Jacques Le Bras; D Camus; C Slomianny
Plasmodium falciparum: detection of P-glycoprotein in chloroquine-susceptible and chloroquine-resistant clones and isolates.
Experimental parasitology 1995;81(1):1-8.
1995: P Eldin de Pécoulas; Leonardo K Basco; B Abdallah; M K Djé; Jacques Le Bras; André Mazabraud
Plasmodium falciparum: detection of antifolate resistance by mutation-specific restriction enzyme digestion.
Experimental parasitology 1995;80(3):483-7.
1995: Leonardo K Basco; F Marquet; M M Makler; Jacques Le Bras
Plasmodium falciparum and Plasmodium vivax: lactate dehydrogenase activity and its application for in vitro drug susceptibility assay.
Experimental parasitology 1995;80(2):260-71.
1995: Leonardo K Basco; P Eldin de Pécoulas; C M Wilson; Jacques Le Bras; André Mazabraud
Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.
Molecular and biochemical parasitology 1995;69(1):135-8.
1994: Olivier Bouchaud; Leonardo K Basco; C Gillotin; François Gimenez; O Ramiliarisoa; B Genissel; E Bouvet; R Farinotti; Jacques Le Bras; Jean-Pierre Coulaud
Clinical efficacy and pharmacokinetics of micronized halofantrine for the treatment of acute uncomplicated falciparum malaria in nonimmune patients.
The American journal of tropical medicine and hygiene 1994;51(2):204-13.
1994: Leonardo K Basco; Jacques Le Bras
In vitro activity of mitochondrial ATP synthetase inhibitors against Plasmodium falciparum.
The Journal of eukaryotic microbiology 1994;41(3):179-83.
1994: Leonardo K Basco; Jacques Le Bras
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Annals of tropical medicine and parasitology 1994;88(2):137-44.
1994: Leonardo K Basco; G Peytavin; François Gimenez; B Genissel; R Farinotti; Jacques Le Bras
In vitro activity of the enantiomers of N-desbutyl derivative of halofantrine.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1994;45(1):45-6.
1994: Leonardo K Basco; R Thor; Jacques Le Bras
Confused malaria chemoprophylaxis.
Lancet 1994;343(8896):550-1.
1994: Leonardo K Basco; S L Andersen; Wilbur K Milhous; Jacques Le Bras; Jonathan L Vennerstrom
In vitro activity of bisquinoline WR268,668 against African clones and isolates of Plasmodium falciparum.
The American journal of tropical medicine and hygiene 1994;50(2):200-5.
1994: Leonardo K Basco; O Ramiliarisoa; Jacques Le Bras
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum.
The American journal of tropical medicine and hygiene 1994;50(2):193-9.
1994: Leonardo K Basco; Jacques Le Bras
In vitro reversal of chloroquine resistance with chlorpheniramine against African isolates of Plasmodium falciparum.
Japanese journal of medical science & biology 1994;47(1):59-63.
1994: Leonardo K Basco; Jacques Le Bras
Short-term in vitro culture of Plasmodium vivax and P. ovale for drug-susceptibility testing.
Parasitology research 1994;80(3):262-4.
1994: François Gimenez; C Gillotin; Leonardo K Basco; Olivier Bouchaud; A F Aubry; irving william wainer; Jacques Le Bras; R Farinotti
Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients.
European journal of clinical pharmacology 1994;46(6):561-2.
1993: P Ringwald; F Peyron; J P Lepers; P Rabarison; C Rakotomalala; M Razanamparany; M Rabodonirina; J Roux; Jacques Le Bras
Parasite virulence factors during falciparum malaria: rosetting, cytoadherence, and modulation of cytoadherence by cytokines.
Infection and immunity 1993;61(12):5198-204.
1993: Leonardo K Basco; Jacques Le Bras
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum.
The American journal of tropical medicine and hygiene 1993;49(3):301-7.
1993: Leonardo K Basco; Jacques Le Bras
Activity in vitro of doxycycline against multidrug-resistant Plasmodium falciparum.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(4):469-70.
1993: Leonardo K Basco; P Ringwald; F Simon; J C Doury; Jacques Le Bras
Evolution of chloroquine resistance in central and west Africa.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1993;44(2):111-2.
1993: P Ringwald; B Dubois; Jacques Le Bras; P Deloron
Plasmodium falciparum: in vitro models of cytoadherence of infected erythrocytes and an analysis with eight different isolates on different target cells.
Experimental parasitology 1993;76(4):442-6.
1993: C Gaudebout; Eric Pussard; F Clavier; D Gueret; Jacques Le Bras; O Brandicourt; F Verdier
Efficacy of intramuscular amopyroquin for treatment of Plasmodium falciparum malaria in the Gabon Republic.
Antimicrobial agents and chemotherapy 1993;37(5):970-4.
1993: Leonardo K Basco; O Ramiliarisoa; P Ringwald; J C Doury; Jacques Le Bras
In vitro activity of cycloguanil against African isolates of Plasmodium falciparum.
Antimicrobial agents and chemotherapy 1993;37(4):924-5.
1993: Leonardo K Basco; Jacques Le Bras
In vitro activity of chloroquine and quinine in combination with desferrioxamine against Plasmodium falciparum.
American journal of hematology 1993;42(4):389-91.
1993: Leonardo K Basco; C Gillotin; François Gimenez; R Farinotti; Jacques Le Bras
Activity in vitro of the enantiomers of halofantrine.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(1):78-9.
1993: Leonardo K Basco; Jacques Le Bras
In vitro activity of monodesethylamodiaquine and amopyroquine against African isolates and clones of Plasmodium falciparum.
The American journal of tropical medicine and hygiene 1993;48(1):120-5.
1992: Leonardo K Basco; Jacques Le Bras
In vitro activity of halofantrine and its relationship to other standard antimalarial drugs against African isolates and clones of Plasmodium falciparum.
The American journal of tropical medicine and hygiene 1992;47(4):521-7.
1992: Leonardo K Basco; Jacques Le Bras
In vitro activity of pyronaridine against African strains of Plasmodium falciparum.
Annals of tropical medicine and parasitology 1992;86(5):447-54.
1992: J C Doury; P Ringwald; J Guelain; Jacques Le Bras
Susceptibility of African isolates of Plasmodium falciparum to artemisinin (qinghaosu).
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1992;43(3):197-8.
1992: Leonardo K Basco; C Gillotin; François Gimenez; R Farinotti; Jacques Le Bras
In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum.
British journal of clinical pharmacology 1992;33(5):517-20.
1992: I Hatin; Jean-François Trape; F Legros; J Bauchet; Jacques Le Bras
Susceptibility of Plasmodium falciparum strains to mefloquine in an urban area in Senegal.
Bulletin of the World Health Organization 1992;70(3):363-7.
1992: Leonardo K Basco; Jacques Le Bras
In vitro activities of chloroquine in combination with chlorpromazine or prochlorperazine against isolates of Plasmodium falciparum.
Antimicrobial agents and chemotherapy 1992;36(1):209-13.
1992: Leonardo K Basco; C Gillotin; François Gimenez; R Farinotti; Jacques Le Bras
Antimalarial activity in vitro of the N-desbutyl derivative of halofantrine.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1992;86(1):12-3.
1992: P Ringwald; P Rabarison; Lucie A Raharimalala; M D Rason; J P Lepers; Jacques Le Bras; Jean Roux
[Stability and chemosensitivity of Plasmodium falciparum to chloroquine in 1990 and 1991 in Ankazobe, a village in high plateau Madagascar].
Bulletin de la Société de pathologie exotique (1990) 1992;85(3):219-22; discussion 222-3.
1992: C Turaman; Leonardo K Basco; Jacques Le Bras
Evaluating the efficacy of chloroquine in febrile Guinean children infected with Plasmodium falciparum by a simplified in vivo test.
Bulletin of the World Health Organization 1992;70(4):477-80.
1992: Jacques Le Bras; Leonardo K Basco; G Cremer; G Charmot
[Contribution of molecular genetics to the understanding of chemoresistance of Plasmodium falciparum].
Bulletin de la Société de pathologie exotique (1990) 1992;85(2):146-9.
1991: Leonardo K Basco; Jacques Le Bras; C Gillotin; P Ringwald; E Rabenjarson; François Gimenez; Olivier Bouchaud; R Farinotti; Jean-Pierre Coulaud
Type RI resistance to halofantrine in West Africa.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft für Technische Zusammenarbeit (GTZ) 1991;42(4):413-4.
1991: Philippe Deloron; L K Basco; B Dubois; C Gaudin; F Clavier; Jacques Le Bras; F Verdier
In vitro and in vivo potentiation of chloroquine against malaria parasites by an enantiomer of amlodipine.
Antimicrobial agents and chemotherapy 1991;35(7):1338-42.
1991: Leonardo K Basco; Jacques Le Bras
Potentiation of monodesethylamodiaquine and amopyroquine with desipramine against Plasmodium falciparum in vitro.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85(4):447-8.
1991: Leonardo K Basco; Jacques Le Bras
Plasmodium falciparum: in vitro drug interaction between chloroquine and enantiomers of amlodipine.
Experimental parasitology 1991;72(3):262-70.
1991: Leonardo K Basco; P Ringwald; Jacques Le Bras
Chloroquine-potentiating action of antihistaminics in Plasmodium falciparum in vitro.
Annals of tropical medicine and parasitology 1991;85(2):223-8.
1991: Eric Pussard; J P Lepers; F Clavier; Lucie A Raharimalala; Jacques Le Bras; M Frisk-Holmberg; Y Bergqvist; F Verdier
Efficacy of a loading dose of oral chloroquine in a 36-hour treatment schedule for uncomplicated plasmodium falciparum malaria.
Antimicrobial agents and chemotherapy 1991;35(3):406-9.
1991: Leonardo K Basco; C Gillotin; François Gimenez; R Farinotti; Jacques Le Bras
Absence of antimalarial activity or interaction with mefloquine enantiomers in vitro of the main human metabolite of mefloquine.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85(2):208-9.
1991: Leonardo K Basco; P Ringwald; Jacques Le Bras
In vivo-in vitro test for chloroquine potentiation by cyproheptadine against Plasmodium falciparum.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85(2):206-7.
1991: Leonardo K Basco; Jacques Le Bras
Reversal of chloroquine resistance with cyproheptadine in 'wild' strains of Plasmodium falciparum.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85(2):204-5.
1991: Jacques Le Bras; P Ringwald; C Monsérié; Leonardo K Basco
[Mefloquine and halofantrine, new therapeutic drugs of malaria].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 1991;12(1):68-74.
1990: K Malhotra; D Salmon; Jacques Le Bras; J L Vilde
Potentiation of chloroquine activity against Plasmodium falciparum by the peroxidase-hydrogen peroxide system.
Antimicrobial agents and chemotherapy 1990;34(10):1981-5.
1990: Leonardo K Basco; Jacques Le Bras
Reversal of chloroquine resistance with desipramine in isolates of Plasmodium falciparum from Central and West Africa.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(4):479-81.
1990: P Ringwald; S Bartczak; Jacques Le Bras; F Bricaire; sophie matheron; J Bauchet; J P Coulaud
Failure of anti-malarial prophylaxis with mefloquine in Africa.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(3):348-9.
1990: D Salmon; F Verdier; K Malhotra; Eric Pussard; F Clavier; Jacques Le Bras; J L Vilde; J J Pocidalo
Absence of effect of chloroquine in vivo on neutrophil oxidative metabolism in human subjects.
The Journal of antimicrobial chemotherapy 1990;25(3):367-70.
1989: Jean-François Trape; F Legros; P Ndiaye; Lassana Konate; IB Bah; Saïdou Diallo; F Verdier; I Hatin; Jacques Le Bras
Chloroquine-resistant Plasmodium falciparum malaria in Senegal.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1989;83(6):761.
1989: F Verdier; Eric Pussard; F Clavier; Jacques Le Bras; C Gaudebout
Pharmacokinetics of intramuscular amopyroquin in healthy subjects and determination of a therapeutic regimen for Plasmodium falciparum malaria.
Antimicrobial agents and chemotherapy 1989;33(3):316-21.
1988: K Malhotra; D Salmon; Jacques Le Bras; J L Vilde
Susceptibility of Plasmodium falciparum to a peroxidase-mediated oxygen-dependent microbicidal system.
Infection and immunity 1988;56(12):3305-9.
1988: K Malhotra; D Salmon; Jacques Le Bras; J Savel; J L Vilde
[Stimulation of the chemiluminescence of human polymorphonuclear leukocytes in various stages of the intraerythrocyte development of Plasmodium falciparum].
Comptes rendus des séances de la Société de biologie et de ses filiales 1988;182(3):270-8.
1987: P Coulanges; Jacques Le Bras; P Deloron; J A Ramanamirija; J M Biaud; H Marchais
[In vivo and in vitro study of the chemosensitivity of Plasmodium falciparum in Madagascar--1982-1986].
Archives de l'Institut Pasteur de Madagascar 1987;53(1):63-76.
1987: H Marchais; J A Ramanamirija; Jacques Le Bras; P Coulanges
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of a study conducted on the east coast (July 1985-July 1986)].
Archives de l'Institut Pasteur de Madagascar 1987;53(1):43-62.
1987: Eric Pussard; F Verdier; F Faurisson; J M Scherrmann; Jacques Le Bras; M C Blayo
Disposition of monodesethylamodiaquine after a single oral dose of amodiaquine and three regimens for prophylaxis against Plasmodium falciparum malaria.
European journal of clinical pharmacology 1987;33(4):409-14.
1987: Jacques Le Bras; F Simon; J A Ramanamirija; M B Calmel; I Hatin; P Deloron; J Porte; H Marchais; J L Clausse; J M Biaud
[Sensitivity of Plasmodium falciparum to quinolines and therapeutic strategies: comparison of the situation in Africa and Madagascar between 1983 and 1986].
Bulletin de la Société de pathologie exotique et de ses filiales 1987;80(3 Pt 2):477-89.
1987: F Simon; J Porte; F Verdier; D Guigon; C Drouville; Jacques Le Bras
[Drug sensitivity of malaria in a population of children in Pointe-Noire, Congo, in the first half of 1986].
Bulletin de la Société de pathologie exotique et de ses filiales 1987;80(3 Pt 2):417-25.
1986: J M Biaud; J A Ramanamirija; O Ramiliarisoa; F Verdier; P Coulanges; Jacques Le Bras
[Drug sensitivity of malaria in Madagascar. Comparison in vivo and in vitro of the effects of chloroquine and amodiaquine on P. falciparum in 1984].
Archives de l'Institut Pasteur de Madagascar 1986;52(1):73-84.
1986: Jacques Le Bras; J A Ramanamirija; J J Benatrehina; J M Biaud; P Coulanges
[Status of malarial endemic in Nosy-Be in February, 1984].
Archives de l'Institut Pasteur de Madagascar 1986;52(1):69-71.
1985: F Verdier; J A Ramanamirija; Eric Pussard; F Clavier; J M Biaud; P Coulanges; Jacques Le Bras
Unreliability of Dill Glazko test in detecting chloroquine in urine.
Lancet 1985;1(8440):1282-3.
1985: F Verdier; Jacques Le Bras; F Clavier; I Hatin; M C Blayo
Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance.
Antimicrobial agents and chemotherapy 1985;27(4):561-4.
1985: J A Ramanamirija; P Deloron; J M Biaud; Jacques Le Bras; P Coulanges
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study].
Bulletin de la Société de pathologie exotique et de ses filiales 1985;78(5):606-14.
1984: F Verdier; Jacques Le Bras; F Clavier; I Hatin
Blood levels and in vitro activity of desethylchloroquine against Plasmodium falciparum.
Lancet 1984;1(8387):1186-7.
1983: F Verdier; Jacques Le Bras; F Clavier
Blood samples and chloroquine assay.
Lancet 1983;1(8335):1227.

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