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Axel Le Cesne

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Axel Le Cesne
13 years of trabectedin, 5 years of Yondelis(®): what have we learnt?
Anna Patrikidou; D Pérol; ISABELLE RAY COQUARD; M Rios; Antoine Adenis; F Bertucci; Jean-Yves Blay; Binh Nguyen Bui; Sylvie Chabaud; Christine Chevreau; Didier Cupissol; Julien Domont; Florence Duffaud; Axel Le Cesne
Influence of imatinib interruption and rechallenge on the residual disease in patients with advanced GIST: results of the BFR14 prospective French Sarcoma Group randomised, phase III trial.
Sacha Mussot; Gerald Simonneau; Dominique Fabre; Elie Fadel; Maria-Rosa Ghigna; Axel Le Cesne; Olaf Mercier; Philippe Dartevelle
Retrospective institutional study of 31 patients treated for pulmonary artery sarcoma.

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All Publications

2013: Axel Le Cesne
13 years of trabectedin, 5 years of Yondelis(®): what have we learnt?
Expert review of anticancer therapy 2013;13(6 Suppl 1):s11-9.
2013: Anna Patrikidou; D Pérol; ISABELLE RAY COQUARD; M Rios; Antoine Adenis; F Bertucci; Jean-Yves Blay; Binh Nguyen Bui; Sylvie Chabaud; Christine Chevreau; Didier Cupissol; Julien Domont; Florence Duffaud; Axel Le Cesne
Influence of imatinib interruption and rechallenge on the residual disease in patients with advanced GIST: results of the BFR14 prospective French Sarcoma Group randomised, phase III trial.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2013;24(4):1087-93.
2013: Sacha Mussot; Gerald Simonneau; Dominique Fabre; Elie Fadel; Maria-Rosa Ghigna; Axel Le Cesne; Olaf Mercier; Philippe Dartevelle
Retrospective institutional study of 31 patients treated for pulmonary artery sarcoma.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2013;43(4):787-93.
2013: Antoine Italiano; Marick Laë; Philippe Lagarde; Axel Le Cesne; Bernard Marques; Jean-Jacques Michels; Nicolas Penel; Sophie Piperno-Neumann; Dominique Ranchere-Vince; Philippe Terrier; Martine Trassard; Jacques-Olivier Bay; Jean-Yves Blay; Sylvie Bonvalot; Céline Brulard; Christine Chevreau; Angela Cioffi; Jean-Michel Coindre; Corinne Delcambre; Nicolas Isambert; Frédéric Chibon
Genetic profiling identifies two classes of soft-tissue leiomyosarcomas with distinct clinical characteristics.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(5):1190-6.
2013: Cécile Le Péchoux; E Musat; Philippe Terrier; H Al Mokhles; C Baey; Julien Domont; Agnès Laplanche; Axel Le Cesne; Sylvie Bonvalot
Should adjuvant radiotherapy be administered in addition to front-line aggressive surgery (FAS) in patients with primary retroperitoneal sarcoma?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2013;24(3):832-7.
2013: George D Demetri; Hans Gelderblom; Peter Hohenberger; Heikki Joensuu; Yoon-Koo Kang; Christian Kappeler; Iris Kuss; Dirk Laurent; Axel Le Cesne; Michael Leahy; ROBERT G MAKI; Binh Bui Nguyen; Toshirou Nishida; Peter Reichardt; Piotr Rutkowski; Patrick Schöffski; Margaret von Mehren; Jianming Xu; Giuseppe Badalamenti; Sebastian Bauer; Martin E Blackstein; Jean-Yves Blay; Paolo G Casali; John Chung
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial.
Lancet 2013;381(9863):295-302.
2013: Jean-Yves Blay; Emmanuelle Bompas; Binh Bui; Philippe A Cassier; Loïc Chaigneau; Jean-Michel Coindre; Olivier Collard; Gauthier Decanter; Olfa Derbel; Florence Duffaud; Nicolas Isambert; Antoine Italiano; Axel Le Cesne; Nadia Badri; François Bertucci; ISABELLE RAY COQUARD; Maria Rios; Patrick Zintl; Nicolas Penel
Long-term outcome and effect of maintenance therapy in patients with advanced sarcoma treated with trabectedin: an analysis of 181 patients of the French ATU compassionate use program.
BMC cancer 2013;13():64.
2012: ISABELLE RAY COQUARD; Ruediger Rueger; Lyubomir T Vassilev; Jianguo Zhi; Jean-Yves Blay; Meichun Ding; David Geho; Bradford Graves; Florian Heil; Antoine Italiano; Axel Le Cesne; Steven A Middleton; Gwen L Nichols; Nicolas Penel; Binh Nguyen Bui
Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study.
The lancet oncology 2012;13(11):1133-40.
2012: Matteo Giaj Levra; Silvia Novello; Mauro Papotti; Giorgio V Scagliotti; Axel Le Cesne
Primary pleuropulmonary sarcoma: a rare disease entity.
Clinical lung cancer 2012;13(6):399-407.
2012: Penella J Woll; Alberto Azzarelli; Sylvie Bonvalot; Vivien H C Bramwell; Harald J Hoekstra; Pancras C W Hogendoorn; Peter Hohenberger; Axel Le Cesne; Michael Leahy; Sandrine Marreaud; Monia Ouali; Peter Reichardt; Frits Van Coevorden; Jaap Verweij
Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial.
The lancet oncology 2012;13(10):1045-54.
2012: Sylvie Bonvalot; S Coppola; A Desai; Julien Dômont; C Le Péchoux; Philippe Terrier; Axel Le Cesne
The treatment of desmoid tumors: a stepwise clinical approach.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23 Suppl 10():x158-66.
2012: Stefan Sleijfer; Jean-Yves Blay; Herman Burger; F Collin; Thierry Gorlia; C Lamers; Axel Le Cesne; Sandrine Marreaud; Lini Pandite; Michelle Scurr; P Hohenberger
Cytokine and angiogenic factors associated with efficacy and toxicity of pazopanib in advanced soft-tissue sarcoma: an EORTC-STBSG study.
British journal of cancer 2012;107(4):639-45.
2012: ISABELLE RAY COQUARD; Axel Le Cesne
A role for maintenance therapy in managing sarcoma.
Cancer treatment reviews 2012;38(5):368-78.
2012: George D Demetri; Christopher R Garrett; David Goldstein; Charles S Harmon; Xin Huang; Herbert I Hurwitz; Axel Le Cesne; Serge Leyvraz; Grant A McArthur; Luis Paz-Ares; Antonio Lopez Pousa; Patrick Schöffski; Manisha H Shah; Vanessa Tassell; Jaap Verweij; Qiang Casey Xu; Jean-Yves Blay; Darrel P Cohen; Paolo G Casali
Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(11):3170-9.
2012: A Italiano; Axel Le Cesne; B Lortal; ROBERT G MAKI; Anna Patrikidou; Nicolas Penel; G K Schwartz; S Singer; M Toulmonde; Cristina R Antonescu; Jean-Yves Blay; Emmanuelle Bompas; Angela Cioffi; Jean-Michel Coindre; Florence Duffaud; N Isambert; Binh Nguyen Bui
Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(6):1601-7.
2012: Axel Le Cesne; ROBERT G MAKI; Jean-Louis Misset; Antonio Nieto; Alejandro Yovine; Jean-Yves Blay; Suzette Delaloge; Pilar Frontelo; Juhui James Jiao; George D Demetri
A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in phase II clinical trials.
Investigational new drugs 2012;30(3):1193-202.
2012: Winette T A van der Graaf; Massimo Aglietta; Nobuhito Araki; Yasuo Beppu; Jean-Yves Blay; Binh Bui-Nguyen; Paolo G Casali; Sant P Chawla; Corneel Coens; Angelo Paolo Dei Tos; George D Demetri; Mohammed R Dewji; Christopher D Fletcher; Hans Gelderblom; Rachel Hodge; Peter Hohenberger; Ian R Judson; Dong-Wan Kim; Axel Le Cesne; Sandrine Marreaud; Monia Ouali; Patrick Schöffski; Arthur P Staddon
Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.
Lancet 2012;379(9829):1879-86.
2012: Jean-Yves Blay; Philippe A Cassier; Axel Le Cesne; Isabelle L Ray-Coquard
Gastrointestinal stromal tumors (GIST): a rare entity, a tumor model for personalized therapy, and yet ten different molecular subtypes.
Discovery medicine 2012;13(72):357-67.
2012: Antoine Italiano; Mary-Louise Keohan; Axel Le Cesne; ROBERT G MAKI; Piotr Rutkowski; Patrick Schöffski; Maud Toulmonde; Antoine Adenis; Cristina R Antonescu; Jean-Yves Blay; Emmanuelle Bompas; Paolo Casali; Angela Cioffi; Paola Coco; Jean-Michel Coindre; Maria Debiec-Rychter; Florence Duffaud; Nicolas Isambert; Binh Nguyen Bui
Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib.
Annals of surgical oncology 2012;19(5):1551-9.
2012: Axel Le Cesne; Jean-Yves Blay
[Medical therapy of GIST; from palliative to curative treatment].
Bulletin de l'Académie nationale de médecine 2012;196(4-5):881-74, 877-84; discussion 874-86.
2012: Nathalie Lassau; Christophe Massard; Baya Benatsou; Sophie Bidault; Jean-Yves Blay; Linda Chami; Mohamed Chebil; Angela Cioffi; Serge Koscielny; Axel Le Cesne
Quantitative functional imaging by dynamic contrast enhanced ultrasonography (DCE-US) in GIST patients treated with masatinib.
Investigational new drugs 2012;30(2):765-71.
2012: George D Demetri; Yong-jiang Hei; Axel Le Cesne; ROBERT G MAKI; Dominic P Smethurst; Bruce A Bach; Sarah Bray; Thomas Brodowicz; Sant P Chawla; Jean-Yves Blay
First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study.
European journal of cancer (Oxford, England : 1990) 2012;48(4):547-63.
2012: Alessandro Gronchi; P Hohenberger; R J Hohl; P Lardelli; Axel Le Cesne; A Nieto; I Pérez; Silvana Pilotti; Elena Tamborini; Juan C Tercero; Sylvie Bonvalot; B N Bui; George D Demetri; Stefano Ferrari; V Alfaro; Jean-Yves Blay
Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(3):771-6.
2012: Olivier Mir; Philippe Terrier; Caroline Trichot; François Lokiec; Narjiss Berrada; Sylvie Bonvalot; Bérénice Boulet; Angela Cioffi; Julien Domont; Axel Le Cesne
Doxorubicin and ifosfamide for high-grade sarcoma during pregnancy.
Cancer chemotherapy and pharmacology 2012;69(2):357-67.
2012: Florence Duffaud; Armelle Dufresne; Caroline Even; Thanh Khoa-Huynh; Axel Le Cesne; ISABELLE RAY COQUARD; Sebastien Salas; Emmanuelle Bompas; Sylvie Bonvalot; Philippe A Cassier; Francoise Ducimetiere; Jean-Yves Blay
Recombinant erythropoietin for the anaemia of patients with advanced Gastrointestinal Stromal Tumours (GIST) receiving imatinib: an active agent only in non progressive patients.
Clinical sarcoma research 2012;2(1):11.
2012: O Hocar; Axel Le Cesne; Cécile Le Pechoux; A Auperin; S Berissi; Sylvie Bonvalot; B Bui; Jean-Michel Coindre; Philippe Terrier; Daniel Vanel; C Robert
Clear cell sarcoma (malignant melanoma) of soft parts: a clinicopathologic study of 52 cases.
Dermatology research and practice 2012;2012():984096.
2012: ISABELLE RAY COQUARD; Yves-Marie Robin; Jacques-Olivier Bay; Jean-Yves Blay; Emmanuelle Bompas; Guilhem Bousquet; Christine Chevreau; Stéphanie Clisant; Olivier Collard; Didier Cupissol; Charles Fournier; Eric Gauthier; Nicolas Isambert; Antoine Italiano; Axel Le Cesne; Laurent Lemaitre; Nicolas Penel; Sophie Piperno-Neumann
Sorafenib for patients with advanced angiosarcoma: a phase II Trial from the French Sarcoma Group (GSF/GETO).
The oncologist 2012;17(2):260-6.
2011: Bruno Landi; Axel Le Cesne; Thierry Lecomte; Geneviève Monges; Bertrand Napoléon; Laurent Palazzo; Jean-Marie Coindre; Jean-François Emile; Marc Giovannini; Rosine Guimbaud; Thomas Aparicio; Anne Berger; Jean-Yves Blay; Sylvie Bonvalot; Olivier Bouché; Christian Boustière; Bruno Buecher; Jean-Alain Chayvialle
Management of gastrointestinal stromal tumours of limited size: proposals from a French panel of physicians.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2011;43(12):935-9.
2011: Patrick Schöffski; Raf Sciot; Jantien Wanders; Sebastian Bauer; Jean-Yves Blay; Nguyen Bin Bui; Angela Cioffi; Herlinde Dumez; Viktor Grünwald; Joerg Thomas Hartmann; Carolyn Hayward; Peter Hohenberger; Anders Krarup-Hansen; Axel Le Cesne; Sandrine Marreaud; Monia Ouali; Isabelle Laure Ray-Coquard
Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes.
The lancet oncology 2011;12(11):1045-52.
2011: Sébastien Salas; Eberhard Stoeckle; Philippe Terrier; Jean-Yves Blay; Sylvie Bonvalot; Véronique Brouste; Binh Nguyen Bui; Armelle Dufresne; Louis Guillou; Axel Le Cesne; Odile Oberlin; Dominique Ranchere-Vince; Jean-Michel Coindre
Prognostic factors influencing progression-free survival determined from a series of sporadic desmoid tumors: a wait-and-see policy according to tumor presentation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(26):3553-8.
2011: A Paumier; F Rimareix; Elena Roberti; Philippe Terrier; Anne Beaudré; Sylvie Bonvalot; Julien Domont; Axel Le Cesne; Dimitri Lefkopoulos; Cécile Le Péchoux
[Intensity modulated radiotherapy as adjuvant post-operative treatment for retroperitoneal sarcoma: acute toxicity].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2011;15(5):413-20.
2011: Antoine Italiano; Jose Jimeno; Ian Judson; Audrey Laroche; Armelle Laurand; Axel Le Cesne; Antonio Nieto; Jean-Yves Blay; Binh Bui; Paolo Casali; Jean-Michel Coindre; ISABELLE RAY COQUARD; Jacques Robert; Roberta Sanfilippo; Juan-Carlos Tercero; Philippe Pourquier
ERCC5/XPG, ERCC1, and BRCA1 gene status and clinical benefit of trabectedin in patients with soft tissue sarcoma.
Cancer 2011;117(15):3445-56.
2011: Anna Patrikidou; Julien Domont; Angela Cioffi; Axel Le Cesne
Treating soft tissue sarcomas with adjuvant chemotherapy.
Current treatment options in oncology 2011;12(1):21-31.
2011: Olivier Mir; Julien Domont; Angela Cioffi; Sylvie Bonvalot; Bérénice Boulet; Cécile Le Pechoux; Philippe Terrier; Marc Spielmann; Axel Le Cesne
Feasibility of metronomic oral cyclophosphamide plus prednisolone in elderly patients with inoperable or metastatic soft tissue sarcoma.
European journal of cancer (Oxford, England : 1990) 2011;47(4):515-9.
2011: Aurore Blesius; Philippe A Cassier; François Bertucci; Jerome Fayette; ISABELLE RAY COQUARD; Binh Bui; Antoine Adenis; Maria Rios; Didier Cupissol; David Pérol; Jean-Yves Blay; Axel Le Cesne
Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial.
BMC cancer 2011;11():72.
2010: A Italiano; F Delva; Simone Mathoulin-Pelissier; Axel Le Cesne; Sylvie Bonvalot; Philippe Terrier; Martine Trassard; Jean-Jacques Michels; Jean-Yves Blay; Jean-Michel Coindre; Binh Nguyen Bui
Effect of adjuvant chemotherapy on survival in FNCLCC grade 3 soft tissue sarcomas: a multivariate analysis of the French Sarcoma Group Database.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(12):2436-41.
2010: Axel Le Cesne; ISABELLE RAY COQUARD; Binh Nguyen Bui; Antoine Adenis; Maria Rios; François Bertucci; Florence Duffaud; Christine Chevreau; Didier Cupissol; Angela Cioffi; Jean-François Emile; Sylvie Chabaud; David Pérol; Jean-Yves Blay
Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial.
The lancet oncology 2010;11(10):942-9.
2010: A Dufresne; F Bertucci; N Penel; Axel Le Cesne; Binh Nguyen Bui; M Tubiana-Hulin; ISABELLE RAY COQUARD; Didier Cupissol; Christine Chevreau; David Perol; A Goncalves; M Jimenez; P P Bringuier; Jean-Yves Blay
Identification of biological factors predictive of response to imatinib mesylate in aggressive fibromatosis.
British journal of cancer 2010;103(4):482-5.
2010: Felipe Andreiuolo; J Calderaro; Yohann Loriot; S Bonvalot; Linda Chami; Axel Le Cesne; S Forget; Marie-Christine Mathieu; Voichita Suciu; Philippe Terrier; Philippe Vielh
KIT expression in postradiation sarcoma.
Cytopathology : official journal of the British Society for Clinical Cytology 2010;21(4):279-80.
2010: Frédéric Chibon; Philippe Lagarde; Sébastien Salas; Gaëlle Pérot; Véronique Brouste; Franck Tirode; Carlo LUCCHESI; Aurélien de Reynies; Audrey Kauffmann; Binh Nguyen Bui; Philippe Terrier; Sylvie Bonvalot; Axel Le Cesne; Dominique Vince-Ranchère; Jean-Yves Blay; Françoise Collin; Louis Guillou; Agnès Leroux; Jean-Michel Coindre; Alain Aurias
Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity.
Nature medicine 2010;16(7):781-7.
2010: M Tardieu; Julien Dômont; Angela Cioffi; Sylvie Bonvalot; Axel Le Cesne
[Focus on GIST management].
Bulletin du cancer 2010;97(6):723-31.
2010: Sylvie Bonvalot; Rosalba Miceli; Mattia Berselli; Sylvain Causeret; Chiara Colombo; Luigi Mariani; Hatem Bouzaiene; Cécile Le Péchoux; Paolo Giovanni Casali; Axel Le Cesne; Marco Fiore; Alessandro Gronchi
Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control.
Annals of surgical oncology 2010;17(6):1507-14.
2010: Axel Le Cesne; Jean-Yves Blay; Binh Nguyen Bui; Olivier Bouché; Antoine Adenis; Julien Domont; Angela Cioffi; ISABELLE RAY COQUARD; Nathalie Lassau; Sylvie Bonvalot; Alain Moussy; Jean-Pierre Kinet; Olivier Hermine
Phase II study of oral masitinib mesilate in imatinib-naïve patients with locally advanced or metastatic gastro-intestinal stromal tumour (GIST).
European journal of cancer (Oxford, England : 1990) 2010;46(8):1344-51.
2010: Julien Domont; Christophe Massard; Nathalie Lassau; Jean-Pierre Armand; Axel Le Cesne; Jean-Charles Soria
Hemangiopericytoma and antiangiogenic therapy: clinical benefit of antiangiogenic therapy (sorafenib and sunitinib) in relapsed malignant haemangioperyctoma /solitary fibrous tumour.
Investigational new drugs 2010;28(2):199-202.
2010: Julien Dômont; S Salas; ludovic lacroix; V Brouste; P Saulnier; Philippe Terrier; Dominique Ranchère; A Neuville; A Leroux; Louis Guillou; Raf Sciot; Françoise Collin; A Dufresne; Jean-Yves Blay; Axel Le Cesne; Jean-Michel Coindre; S Bonvalot; Jean Bénard
High frequency of beta-catenin heterozygous mutations in extra-abdominal fibromatosis: a potential molecular tool for disease management.
British journal of cancer 2010;102(6):1032-6.
2010: Stefan Sleijfer; Monia Ouali; Martine Van Glabbeke; Anders Krarup-Hansen; Sjoerd Rodenhuis; Axel Le Cesne; Pancras C W Hogendoorn; Jaap Verweij; Jean-Yves Blay
Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas: an exploratory, retrospective analysis on large series from the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG).
European journal of cancer (Oxford, England : 1990) 2010;46(1):72-83.
2009: Sylvie Bonvalot; Françoise Rimareix; Sylvain Causeret; Cécile Le Péchoux; Bérénice Boulet; Philippe Terrier; Axel Le Cesne; Jane Muret
Hyperthermic isolated limb perfusion in locally advanced soft tissue sarcoma and progressive desmoid-type fibromatosis with TNF 1 mg and melphalan (T1-M HILP) is safe and efficient.
Annals of surgical oncology 2009;16(12):3350-7.
2009: Jean-Yves Blay; Axel Le Cesne
Adjuvant chemotherapy in localized soft tissue sarcomas: still not proven.
The oncologist 2009;14(10):1013-20.
2009: George D Demetri; Sant P Chawla; Margaret von Mehren; Paul Ritch; Laurence H Baker; Jean Y Blay; Kenneth R Hande; Mary-Louise Keohan; Brian L Samuels; Scott M Schuetze; Claudia Lebedinsky; Yusri A Elsayed; Miguel A Izquierdo; Javier Gómez; Youn C Park; Axel Le Cesne
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(25):4188-96.
2009: Marco Fiore; Françoise Rimareix; Luigi Mariani; Julien Domont; Paola Collini; Cecile Le Péchoux; Paolo G Casali; Axel Le Cesne; Alessandro Gronchi; Sylvie Bonvalot
Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment.
Annals of surgical oncology 2009;16(9):2587-93.
2009: Axel Le Cesne; Martine Van Glabbeke; Jaap Verweij; Paolo G Casali; Michael Findlay; Peter Reichardt; Rolf Issels; Ian Judson; Patrick Schoffski; Serge Leyvraz; Binh Nguyen Bui; Pancras C W Hogendoorn; Raf Sciot; Jean-Yves Blay
Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(24):3969-74.
2009: Robert S Benjamin; Maria Debiec-Rychter; Axel Le Cesne; Stefan Sleijfer; George D Demetri; Heikki Joensuu; Patrick Schöffski; Andrés Poveda
Gastrointestinal stromal tumors II: medical oncology and tumor response assessment.
Seminars in oncology 2009;36(4):302-11.
2009: ISABELLE RAY COQUARD; Claire Cropet; Martine Van Glabbeke; Catherine Sebban; Axel Le Cesne; Ian Judson; Olivier Tredan; Jaap Verweij; Pierre Biron; Inthidar Labidi; Jean-Paul Guastalla; Thomas Bachelot; David Perol; Sylvie Chabaud; Pancras Hogendoorn; Philippe A Cassier; Armelle Dufresne; Jean-Yves Blay
Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas.
Cancer research 2009;69(13):5383-91.
2009: Jean-Yves Blay; Antoine Adenis; ISABELLE RAY COQUARD; Philippe A Cassier; Axel Le Cesne
Is there a role for discontinuing imatinib in patients with advanced gastrointestinal stromal tumour?
Current opinion in oncology 2009;21(4):360-6.
2009: Stefan Sleijfer; ISABELLE RAY COQUARD; Zsuzsa Papai; Axel Le Cesne; Michelle Scurr; Patrick Schöffski; Françoise Collin; Lini Pandite; Sandrine Marreaud; Annick De Brauwer; Martine Van Glabbeke; Jaap Verweij; Jean-Yves Blay
Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(19):3126-32.
2009: Axel Le Cesne; Julien Domont; Angela Cioffi; S Bonvalot; P Terrier; ISABELLE RAY COQUARD; V Alfaro; C Lebedinsky; P Santabarbara; Jean-Yves Blay
Mapping the literature: role of trabectedin as a new chemotherapy option in advanced pretreated soft tissue sarcoma.
Drugs of today (Barcelona, Spain : 1998) 2009;45(6):403-21.
2009: Alessandro Gronchi; Sylvie Bonvalot; Axel Le Cesne; Paolo G Casali
Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(12):2106-7; author reply 2107-8.
2009: Cédric Ménard; Jean-Yves Blay; Christophe Borg; Stefan Michiels; François Ghiringhelli; Caroline Robert; Céline Nonn; Nathalie Chaput; Julien Taïeb; Nicolas F Delahaye; Caroline Flament; Jean-François Emile; Axel Le Cesne; Laurence Zitvogel
Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients.
Cancer research 2009;69(8):3563-9.
2009: Mylène Mabille; Daniel Vanel; Marcella Albiter; Axel Le Cesne; Sylvie Bonvalot; Cécile Le Péchoux; Philippe Terrier; Lorraine G Shapeero; Clarisse Dromain
Follow-up of hepatic and peritoneal metastases of gastrointestinal tumors (GIST) under Imatinib therapy requires different criteria of radiological evaluation (size is not everything!!!).
European journal of radiology 2009;69(2):204-8.
2009: Florence Duffaud; Axel Le Cesne
Imatinib in the treatment of solid tumours.
Targeted oncology 2009;4(1):45-56.
2009: Sylvie Bonvalot; Michel Rivoire; Marine Castaing; Eberhard Stoeckle; Axel Le Cesne; Jean Yves Blay; Agnès Laplanche
Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(1):31-7.
2008: Jean-Yves Blay; Margaret von Mehren; Brian L Samuels; Michael P Fanucchi; ISABELLE RAY COQUARD; Brigid Buckley; Leen Gilles; Claudia Lebedinsky; Yusri A Elsayed; Axel Le Cesne
Phase I combination study of trabectedin and doxorubicin in patients with soft-tissue sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(20):6656-62.
2008: ISABELLE RAY COQUARD; Axel Le Cesne; Jeremy S Whelan; Patrick Schoffski; Binh N Bui; Jaap Verweij; Sandrine Marreaud; Martine Van Glabbeke; Pancras Hogendoorn; Jean-Yves Blay
A phase II study of gefitinib for patients with advanced HER-1 expressing synovial sarcoma refractory to doxorubicin-containing regimens.
The oncologist 2008;13(4):467-73.
2008: J Muret; M Yacoub; Philippe Terrier; F Drusch; Agnès Laplanche; C Gaudin; Catherine Richon; Cécile Le Péchoux; Axel Le Cesne; F J Lejeune; Thomas Tursz; Pierre Fouret; Sylvie Bonvalot; Salem Chouaib
p53 status correlates with histopathological response in patients with soft tissue sarcomas treated using isolated limb perfusion with TNF-alpha and melphalan.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(4):793-800.
2008: Sylvie Bonvalot; Hany Eldweny; V Haddad; F Rimareix; Gilles Missenard; O Oberlin; Daniel Vanel; Philippe Terrier; Jean-Yves Blay; Axel Le Cesne; Cécile Le Péchoux
Extra-abdominal primary fibromatosis: Aggressive management could be avoided in a subgroup of patients.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2008;34(4):462-8.
2008: Séverine Tabone-Eglinger; Radislav Bahleda; Jean-François Côté; Philippe Terrier; Dominique Vidaud; Anne Cayre; Alain Beauchet; Nathalie Théou-Anton; Marie-José Terrier-Lacombe; Antoinette Lemoine; Frédérique Penault-Llorca; Axel Le Cesne; Jean-François Emile
Frequent EGFR Positivity and Overexpression in High-Grade Areas of Human MPNSTs.
Sarcoma 2008;2008():849156.
2008: Kaouthar Khanfir; Agnes Chompret; Eric Frau; Eric Bloch-Michel; Thomas Tursz; Axel Le Cesne
An unusual variant of diffuse retinoblastoma in an adult.
Acta oncologica (Stockholm, Sweden) 2008;47(5):973-4.
2007: Jérôme Fayette; E Martin; Sophie Piperno-Neumann; Axel Le Cesne; C Robert; Sylvie Bonvalot; Dominique Ranchère; Pierre Pouillart; J M Coindre; Jean-Yves Blay
Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(12):2030-6.
2007: Paul Lorigan; Jaap Verweij; Zsuzsa Papai; Sjoerd Rodenhuis; Axel Le Cesne; Michael G Leahy; John A Radford; Martine Van Glabbeke; Anne Kirkpatrick; Pancras Hogendoorn; Jean-Yves Blay
Phase III trial of two investigational schedules of ifosfamide compared with standard-dose doxorubicin in advanced or metastatic soft tissue sarcoma: a European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(21):3144-50.
2007: George D Demetri; Robert S Benjamin; Charles D Blanke; Jean-Yves Blay; Paolo Casali; Haesun Choi; Christopher L Corless; Maria Debiec-Rychter; Ronald P DeMatteo; David S Ettinger; George A Fisher; Christopher D M Fletcher; Alessandro Gronchi; Peter Hohenberger; Miranda Hughes; Heikki Joensuu; Ian Judson; Axel Le Cesne; ROBERT G MAKI; Michael Morse; Alberto S Pappo; Peter W T Pisters; Chandrajit P Raut; Peter Reichardt; Douglas S Tyler; Annick D Van den Abbeele; Margaret von Mehren; Jeffrey D Wayne; John Zalcberg
NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines.
Journal of the National Comprehensive Cancer Network : JNCCN 2007;5 Suppl 2():S1-29; quiz S30.
2007: Federica Grosso; Robin L Jones; George D Demetri; Ian R Judson; Jean-Yves Blay; Axel Le Cesne; Roberta Sanfilippo; Paola Casieri; Paola Collini; Palma Dileo; Carlo Spreafico; Silvia Stacchiotti; Elena Tamborini; Juan C Tercero; José Jimeno; Maurizio D'Incalci; Alessandro Gronchi; Jonathan A Fletcher; Silvana Pilotti; Paolo G Casali
Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study.
The lancet oncology 2007;8(7):595-602.
2007: François Ghiringhelli; Cedric Menard; Pierre-Emmanuel Puig; Sylvain Ladoire; Stephan Roux; François Martin; Eric Solary; Axel Le Cesne; Laurence Zitvogel; Bruno Chauffert
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients.
Cancer immunology, immunotherapy : CII 2007;56(5):641-8.
2007: Jaap Verweij; Paolo G Casali; Dusan Kotasek; Axel Le Cesne; Peter Reichard; Ian R Judson; Rolf Issels; Allan T van Oosterom; Martine Van Glabbeke; Jean-Yves Blay
Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients: analysis of EORTC-ISG-AGITG study 62005.
European journal of cancer (Oxford, England : 1990) 2007;43(6):974-8.
2007: Jean-Yves Blay; Axel Le Cesne; ISABELLE RAY COQUARD; Binh Nguyen Bui; Florence Duffaud; Catherine Delbaldo; Antoine Adenis; Patrice Viens; Maria Rios; Emmanuelle Bompas; Didier Cupissol; Cecile Guillemet; Pierre Kerbrat; Jérôme Fayette; Sylvie Chabaud; Patrice Berthaud; David Perol
Prospective multicentric randomized phase III study of imatinib in patients with advanced gastrointestinal stromal tumors comparing interruption versus continuation of treatment beyond 1 year: the French Sarcoma Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(9):1107-13.
2007: Sylvie Bonvalot; Marc Bonnay; L Drouard-Troalen; Andrea Cavalcanti; Cécile Le Péchoux; Axel Le Cesne; Jean-Yves Blay; F Laborde
Pressure-suit combined with pelvic stop-flow: a feasibility study in a bovine model.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2007;33(1):114-8.
2007: Michael Leahy; ISABELLE RAY COQUARD; Jaap Verweij; Axel Le Cesne; Florence Duffaud; Pancras Hogendoorn; Camilla Fowst; Christine de Balincourt; Eugenio Donato Di Paola; Martine Van Glabbeke; Ian Judson; Jean-Yves Blay
Brostallicin, an agent with potential activity in metastatic soft tissue sarcoma: a phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group.
European journal of cancer (Oxford, England : 1990) 2007;43(2):308-15.
2006: Jean-Yves Blay; Sylvie Bonvalot; Jérôme Fayette; Eberhart Stockle; ISABELLE RAY COQUARD; Jean-Michel Coindre; Florence Duffaud; Sophie Taieb; Marie-Pierre Sunyach; Dominique Ranchere; Pierre Meeus; Axel Le Cesne; Binh Nguyen Bui
[Neoadjuvant chemotherapy in sarcoma].
Bulletin du cancer 2006;93(11):1093-8.
2006: Nathalie Lassau; Michele Lamuraglia; Linda Chami; Jérome Leclère; Sylvie Bonvalot; Philippe Terrier; Alain Roche; Axel Le Cesne
Gastrointestinal stromal tumors treated with imatinib: monitoring response with contrast-enhanced sonography.
AJR. American journal of roentgenology 2006;187(5):1267-73.
2006: Sylvie Bonvalot; Marie-Christine Missana; Axel Le Cesne; Gilles Missenard; Daniel Vanel; Philippe Terrier; Cécile Le Péchoux
[Function preserving surgery of limb sarcomas: history and improvements].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2006;10(6-7):416-24.
2006: Catherine Delbaldo; Etienne Chatelut; Micheline Ré; Alain Deroussent; Sophie Séronie-Vivien; Aurore Jambu; Patrice Berthaud; Axel Le Cesne; Jean-Yves Blay; Gilles Vassal
Pharmacokinetic-pharmacodynamic relationships of imatinib and its main metabolite in patients with advanced gastrointestinal stromal tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):6073-8.
2006: Charles Court; L Bosca; Axel Le Cesne; Jacques Yves Nordin; Gilles Missenard
Surgical excision of bone sarcomas involving the sacroiliac joint.
Clinical orthopaedics and related research 2006;451():189-94.
2006: Martine Van Glabbeke; Jaap Verweij; Paolo G Casali; R John Simes; Axel Le Cesne; Peter Reichardt; Rolf Issels; Ian R Judson; Allan T van Oosterom; Jean-Yves Blay
Predicting toxicities for patients with advanced gastrointestinal stromal tumours treated with imatinib: a study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Trials Group (EORTC-ISG-AGITG).
European journal of cancer (Oxford, England : 1990) 2006;42(14):2277-85.
2006: Jacques-Olivier Bay; ISABELLE RAY COQUARD; Jérôme Fayette; Serge Leyvraz; Stephane Cherix; Sophie Piperno-Neumann; Christine Chevreau; Nicolas Isambert; Etienne Brain; Georges Emile; Axel Le Cesne; Angela Cioffi; Fabrice Kwiatkowski; Jean-Michel Coindre; Nguyon Binh Bui; Frédéric Peyrade; Nicolas Penel; Jean-Yves Blay
Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: a retrospective analysis.
International journal of cancer. Journal international du cancer 2006;119(3):706-11.
2006: Axel Le Cesne; Bruno Landi; Sylvie Bonvalot; Geneviève Monges; ISABELLE RAY COQUARD; Florence Duffaud; B Bui Nguyen; Roland Bugat; Jean-Alain Chayvialle; P Rougier; Olivier Bouché; Françoise Bonichon; Nathalie Lassau; Daniel Vanel; Bernard Nordlinger; Eberhard Stoeckle; Pierre Meeus; Jean-Michel Coindre; Jean-Yves Scoazec; J F Emile; Dominique Ranchère; Jean-Yves Blay
[Recommendations for the management of gastro-intestinal stromal tumors].
Annales de pathologie 2006;26(3):231-4.
2006: Cécile Le Péchoux; P Pautier; Martine Delannes; Binh Nguyen Bui; Françoise Bonichon; Sylvie Bonvalot; A Chevalier-Place; Jean-Michel Coindre; Axel Le Cesne; Philippe Morice; ISABELLE RAY COQUARD; E Stöeckle; S Taieb
[Clinical practice guidelines: 2006 update of recommendations for the radiotherapeutic management of patients with soft tissue sarcoma (sarcoma of the extremity, uterine sarcoma and retroperitoneal sarcoma].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2006;10(4):185-207.
2006: Maria Debiec-Rychter; Raf Sciot; Axel Le Cesne; Marcus Schlemmer; Peter Hohenberger; Allan T van Oosterom; Jean-Yves Blay; Serge Leyvraz; Michel Stul; Paolo G Casali; John Zalcberg; Jaap Verweij; Martine Van Glabbeke; Anne Hagemeijer; Ian Judson
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours.
European journal of cancer (Oxford, England : 1990) 2006;42(8):1093-103.
2006: Sylvie Bonvalot; Axel Le Cesne
[Diagnosis and treatment of gastrointestinal stromal tumours].
La Revue du praticien 2006;56(4):359-67.
2006: Cécile Le Péchoux; Sylvie Bonvalot; Axel Le Cesne; Elena Roberti; Daniel Vanel; Philippe Terrier; Gilles Missenard; Jean-Louis Habrand
[Place and technical aspects of external beam radiation therapy in the treatment of adult soft tissue sarcomas].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2006;10(1-2):50-62.
2006: Sylvie Bonvalot; Daniel Vanel; Axel Le Cesne; Philippe Terrier; Cécile Le Péchoux
[Surgery of retroperitoneal sarcomas].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2006;10(1-2):41-9.
2005: Nathalie Théou; Sophie Gil; Anne Devocelle; Catherine Julié; Anne Lavergne-Slove; Alain Beauchet; patrice callard; Robert Farinotti; Axel Le Cesne; Antoinette Lemoine; Laurence Faivre-Bonhomme; Jean-François Emile
Multidrug resistance proteins in gastrointestinal stromal tumors: site-dependent expression and initial response to imatinib.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7593-8.
2005: Jean-Yves Blay; Bruno Landi; Sylvie Bonvalot; Geneviève Monges; ISABELLE RAY COQUARD; Florence Duffaud; Nguyen Binh Bui; Roland Bugat; Jean-Alain Chayvialle; Philippe Rougier; Olivier Bouché; Françoise Bonichon; Nathalie Lassau; Daniel Vanel; Bernard Nordlinger; Eberhard Stoeckle; Pierre Meeus; Jean-Michel Coindre; Jean-Yves Scoazec; Jean-François Emile; Dominique Ranchère; Axel Le Cesne
[Recommendations for the management of GIST patients].
Bulletin du cancer 2005;92(10):907-18.
2005: Sylvie Bonvalot; Andrea Cavalcanti; Cécile Le Péchoux; Philippe Terrier; Daniel Vanel; Jean-Yves Blay; Axel Le Cesne; Dominique Elias
Randomized trial of cytoreduction followed by intraperitoneal chemotherapy versus cytoreduction alone in patients with peritoneal sarcomatosis.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2005;31(8):917-23.
2005: Martine Van Glabbeke; Jaap Verweij; Paolo G Casali; Axel Le Cesne; Peter Hohenberger; ISABELLE RAY COQUARD; Marcus Schlemmer; Allan T van Oosterom; David Goldstein; Raf Sciot; Pancras Hogendoorn; Michelle Brown; Rossella Bertulli; Ian R Judson
Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(24):5795-804.
2005: John Zalcberg; Jaap Verweij; Paolo G Casali; Axel Le Cesne; Peter Reichardt; Jean-Yves Blay; Marcus Schlemmer; Martine Van Glabbeke; Michelle Brown; Ian R Judson
Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg.
European journal of cancer (Oxford, England : 1990) 2005;41(12):1751-7.
2005: Caroline Robert; Jean-Charles Soria; Alain Spatz; Axel Le Cesne; David Malka; Patricia Pautier; Janine Wechsler; Catherine Lhomme; Bernard Escudier; Valérie Boige; Jean-Pierre Armand; Thierry Le Chevalier
Cutaneous side-effects of kinase inhibitors and blocking antibodies.
The lancet oncology 2005;6(7):491-500.
2005: Sylvie Bonvalot; Agnès Laplanche; F Lejeune; Eberhard Stoeckle; Cécile Le Péchoux; Daniel Vanel; Philippe Terrier; Jean Lumbroso; Marcel Ricard; G Antoni; Andrea Cavalcanti; C Robert; Nathalie Lassau; Jean-Yves Blay; Axel Le Cesne
Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-alpha be better?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(7):1061-8.
2005: Nathalie Lassau; Michele Lamuraglia; Daniel Vanel; Axel Le Cesne; Linda Chami; S Jaziri; Philippe Terrier; Alain Roche; Jerome Leclere; Sylvie Bonvalot
Doppler US with perfusion software and contrast medium injection in the early evaluation of isolated limb perfusion of limb sarcomas: prospective study of 49 cases.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(7):1054-60.
2005: Daniel Vanel; Marcella Albiter; Lorraine G Shapeero; Axel Le Cesne; Sylvie Bonvalot; Cécile Le Pechoux; Philippe Terrier; Peter Petrow; Hubert Caillet; Clarisse Dromain
Role of computed tomography in the follow-up of hepatic and peritoneal metastases of GIST under imatinib mesylate treatment: a prospective study of 54 patients.
European journal of radiology 2005;54(1):118-23.
2005: Jean-Yves Blay; Sylvie Bonvalot; Paolo Casali; H Choi; M Debiec-Richter; A P Dei Tos; J-F Emile; Alessandro Gronchi; Pancras Hogendoorn; Heikki Joensuu; Axel Le Cesne; J McClure; J Mac Clure; J Maurel; N Nupponen; ISABELLE RAY COQUARD; P Reichardt; R Sciot; S Stroobants; Martine Van Glabbeke; Allan van Oosterom; George D Demetri
Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(4):566-78.
2005: Jean-Yves Blay; Axel Le Cesne; laurent alberti; Isabelle Ray-Coquart
Targeted cancer therapies.
Bulletin du cancer 2005;92(2):E13-8.
2005: Axel Le Cesne; Jean-Yves Blay; Ian Judson; Allan van Oosterom; Jaap Verweij; John Radford; Paul Lorigan; S Rodenhuis; ISABELLE RAY COQUARD; Sylvie Bonvalot; Françoise Collin; José Jimeno; Eugenio Donato Di Paola; Martine Van Glabbeke; Ole Steen Nielsen
Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(3):576-84.
2004: Thomas Aparicio; Valérie Boige; Jean-Christophe Sabourin; Pascal CRENN; Michel Ducreux; Axel Le Cesne; Sylvie Bonvalot
Prognostic factors after surgery of primary resectable gastrointestinal stromal tumours.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2004;30(10):1098-103.
2004: Sylvie Bonvalot; Daniel Vanel; Philippe Terrier; Caroline Robert; Axel Le Cesne; Cécile Le Péchoux
[Management of recurrent soft tissue sarcoma of the retroperitoneum].
Bulletin du cancer 2004;91(11):845-52.
2004: Christophe Borg; Magali Terme; Julien Taïeb; Cédric Ménard; Caroline Flament; Caroline Robert; Koji Maruyama; Hiro Wakasugi; Eric Angevin; Kris Thielemans; Axel Le Cesne; Véronique Chung-Scott; Vladimir Lazar; Isabelle Tchou; Florent Crépineau; francois Lemoine; Jacky Bernard; Jonhantan A Fletcher; Ali G Turhan; Jean-Yves Blay; Alain Spatz; Jean-François Emile; Michael C Heinrich; Salaheddine Mécheri; Thomas Tursz; Laurence Zitvogel
Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects.
The Journal of clinical investigation 2004;114(3):379-88.
2004: Jean-François Emile; Nathalie Théou; Séverine Tabone; Annie Cortez; Philippe Terrier; Marie-Thérèse Chaumette; Catherine Julié; Philippe Bertheau; Anne Lavergne-Slove; jean donadieu; Alain Barrier; Axel Le Cesne; Brigitte Debuire; Antoinette Lemoine
Clinicopathologic, phenotypic, and genotypic characteristics of gastrointestinal mesenchymal tumors.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004;2(7):597-605.
2004: Nathalie Théou; Séverine Tabone; Raphaël Saffroy; Axel Le Cesne; Catherine Julié; Annie Cortez; Anne Lavergne-Slove; Brigitte Debuire; Antoinette Lemoine; Jean-François Emile
High expression of both mutant and wild-type alleles of c-kit in gastrointestinal stromal tumors.
Biochimica et biophysica acta 2004;1688(3):250-6.
2004: Yannick Le Guen; Axel Le Cesne
[Docetaxel and non-small cell lung cancer].
Bulletin du cancer 2004;91(3):263-70.
2003: Jaap Verweij; Allan van Oosterom; Jean-Yves Blay; Ian Judson; S Rodenhuis; W van der Graaf; John Radford; Axel Le Cesne; Pancras Hogendoorn; Eugenio Donato Di Paola; M Brown; Ole Steen Nielsen
Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study.
European journal of cancer (Oxford, England : 1990) 2003;39(14):2006-11.
2003: Kaouthar Khanfir; L Alzieu; Philippe Terrier; Cécile Le Péchoux; Sylvie Bonvalot; Daniel Vanel; Axel Le Cesne
Does adjuvant radiation therapy increase loco-regional control after optimal resection of soft-tissue sarcoma of the extremities?
European journal of cancer (Oxford, England : 1990) 2003;39(13):1872-80.
2003: Laurent Zelek; Antonio Llombart-Cussac; Philippe Terrier; Xavier Pivot; Jean-Marc Guinebretiere; Cécile Le Pechoux; Thomas Tursz; France Rochard; Marc Spielmann; Axel Le Cesne
Prognostic factors in primary breast sarcomas: a series of patients with long-term follow-up.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(13):2583-8.
2003: Kaouthar Khanfir; Jean-Marc Guinebretiere; Daniel Vanel; Lise Barreau-Pouhaer; Sylvie Bonvalot; Axel Le Cesne
Unusual problems in breast cancer and a rare lung cancer case. Case 2. Aggressive fibromatosis of the chest wall arising near a breast prosthesis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(11):2216-8.
2003: ISABELLE RAY COQUARD; Christophe Borg; Thomas Bachelot; Catherine Sebban; Irène Philip; Gilles Clapisson; Axel Le Cesne; Pierre Biron; Franck Chauvin; Jean-Yves Blay
Baseline and early lymphopenia predict for the risk of febrile neutropenia after chemotherapy.
British journal of cancer 2003;88(2):181-6.
2003: ISABELLE RAY COQUARD; Axel Le Cesne; Véronique Michallet; Ioannis Boukovinas; Dominique Ranchere; Philippe Thiesse; Vincent Baty; Jean-Yves Blay
[Gastro-intestinal stromal tumors: news and comments].
Bulletin du cancer 2003;90(1):69-76.
2002: Patricia Pautier; C Genestie; K Fizazi; Philippe Morice; C Mottet; Christine Haie-Meder; Axel Le Cesne; Catherine Lhommé
Cisplatin-based chemotherapy regimen (DECAV) for uterine sarcomas.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2002;12(6):749-54.
2002: L Svancárová; Jean-Yves Blay; Ian R Judson; Q G C M van Hoesel; Allan T van Oosterom; Axel Le Cesne; HJ Keizer; C Hermans; Martine Van Glabbeke; Jaap Verweij; Pancras Hogendoorn; Ole Steen Nielsen
Gemcitabine in advanced adult soft-tissue sarcomas. A phase II study of the EORTC Soft Tissue and Bone Sarcoma Group.
European journal of cancer (Oxford, England : 1990) 2002;38(4):556-9.
2001: Laurent Zelek; S Barthier; M Riofrio; Karim Fizazi; Olivier Rixe; Jean-Pierre Delord; Axel Le Cesne; Marc Spielmann
Weekly vinorelbine is an effective palliative regimen after failure with anthracyclines and taxanes in metastatic breast carcinoma.
Cancer 2001;92(9):2267-72.
2001: Sylvie Bonvalot; F Kolb; K Mamlouk; A Cayalcanti; Cécile Le Pechoux; Philippe Terrier; Daniel Vanel; Axel Le Cesne
[Free-flap reconstruction of locally advanced soft tissue sarcomas].
Annales de chirurgie 2001;126(4):308-13.
2001: Ian Judson; John A Radford; M Harris; Jean-Yves Blay; Q G C M van Hoesel; Axel Le Cesne; Allan T van Oosterom; M J Clemons; Claus Kamby; C Hermans; J Whittaker; Eugenio Donato di Paola; Jaap Verweij; S Nielsen
Randomised phase II trial of pegylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: a study by the EORTC Soft Tissue and Bone Sarcoma Group.
European journal of cancer (Oxford, England : 1990) 2001;37(7):870-7.
2000: Axel Le Cesne; Ian Judson; D Crowther; Sjoerd Rodenhuis; HJ Keizer; Q G C M van Hoesel; Jean-Yves Blay; J Frisch; Martine Van Glabbeke; C Hermans; Allan van Oosterom; T Tursz; Jaap Verweij
Randomized phase III study comparing conventional-dose doxorubicin plus ifosfamide versus high-dose doxorubicin plus ifosfamide plus recombinant human granulocyte-macrophage colony-stimulating factor in advanced soft tissue sarcomas: A trial of the European Organization for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(14):2676-84.
2000: Ole Steen Nielsen; Ian Judson; Q G C M van Hoesel; Axel Le Cesne; HJ Keizer; Jean-Yves Blay; Allan van Oosterom; John A Radford; L Svancárová; K Krzemienlecki; C Hermans; Martine Van Glabbeke; J W Oosterhuis; Jaap Verweij
Effect of high-dose ifosfamide in advanced soft tissue sarcomas. A multicentre phase II study of the EORTC Soft Tissue and Bone Sarcoma Group.
European journal of cancer (Oxford, England : 1990) 2000;36(1):61-7.
1999: Marc Spielmann; Antonio Llombart; Laurent Zelek; R Sverdlin; Olivier Rixe; Axel Le Cesne
Docetaxel-cisplatin combination (DC) chemotherapy in patients with anthracycline-resistant advanced breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(12):1457-60.
1999: Cécile Le Péchoux; Marie-Cécile Le Deley; Suzette Delaloge; Eric Lartigau; C Levy-Piedbois; Sylvie Bonvalot; Axel Le Cesne; Gilles Missenard; Philippe Terrier; Daniel Vanel; J Genin; F Fontaine
Postoperative radiotherapy in the management of adult soft tissue sarcoma of the extremities: results with two different total dose, fractionation, and overall treatment time schedules.
International journal of radiation oncology, biology, physics 1999;44(4):879-86.
1999: O Merimsky; Thierry Le Chevalier; Gilles Missenard; C Lepechoux; I Cojean-Zelek; Benoît Mesurolle; Axel Le Cesne
Management of cancer in pregnancy: a case of Ewing's sarcoma of the pelvis in the third trimester.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(3):345-50.
1999: O Merimsky; P Terrier; A Stanca; Thierry Le Chevalier; Marc Spielmann; Thomas Tursz; Axel Le Cesne
Liver metastases from extremity soft tissue sarcoma.
American journal of clinical oncology 1999;22(1):70-2.
1999: O Merimsky; Philippe Terrier; Sylvie Bonvalot; Cécile Le Pechoux; Jean-Pierre Delord; Axel Le Cesne
Spermatic cord sarcoma in adults.
Acta oncologica (Stockholm, Sweden) 1999;38(5):635-8.
1998: Antonio Llombart-Cussac; Xavier Pivot; Genevieve Contesso; A Rhor-Alvarado; Jean-Pierre Delord; Marc Spielmann; T Türsz; Axel Le Cesne
Adjuvant chemotherapy for primary cardiac sarcomas: the IGR experience.
British journal of cancer 1998;78(12):1624-8.
1998: Karim Fizazi; Nicole Dohollou; Jean-Yves Blay; Sylvie Guérin; Axel Le Cesne; Fabrice André; Pierre Pouillart; Thomas Tursz; B B Nguyen
Ewing's family of tumors in adults: multivariate analysis of survival and long-term results of multimodality therapy in 182 patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(12):3736-43.
1998: Antonio Llombart-Cussac; Xavier Pivot; A Rhor-Alvarado; Axel Le Cesne; Thierry Le Chevalier; Thomas Tursz; Marc Spielmann
First-line vinorelbine-mitoxantrone combination in metastatic breast cancer patients relapsing after an adjuvant anthracycline regimen: results of a phase II study.
Oncology 1998;55(5):384-90.
1998: A Hasbini; Eric Lartigau; Cécile Le Péchoux; A Acharki; Daniel Vanel; J Genin; Axel Le Cesne
[Chondrosarcoma in Ollier's disease. Apropos of 2 cases and review of the literature].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 1998;2(4):387-91.
1998: O Merimsky; Axel Le Cesne
Soft tissue and bone sarcomas in association with pregnancy.
Acta oncologica (Stockholm, Sweden) 1998;37(7-8):721-7.
1997: Philippe Girard; L Spaggiari; P Baldeyrou; Thierry Le Chevalier; Axel Le Cesne; B Escudier; M Filaire; Dominique Grunenwald
Should the number of pulmonary metastases influence the surgical decision?
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1997;12(3):385-91; discussion 392.
1997: Daniel Vanel; Gilles Missenard; Axel Le Cesne; Jean-Marc Guinebretière
Red marrow recolonization induced by growth factors mimicking an increase in tumor volume during preoperative chemotherapy: MR study.
Journal of computer assisted tomography 1997;21(4):529-31.
1997: Axel Le Cesne; Rodrigo Arriagada; Dominique Grunenwald; P Baldeyrou; Philippe Girard; JJ Bretel; Thierry Le Chevalier
[New therapeutic strategies and current research in inoperable locally advanced non small-cell lung cancers (stage IIIB)].
Bulletin du cancer 1997;84(4):413-9.
1997: Miriam Merad; Axel Le Cesne; P Baldeyrou; Benoît Mesurolle; Thierry Le Chevalier
Docetaxel and interstitial pulmonary injury.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(2):191-4.
1997: Karim Fizazi; fadi farhat; Christine Theodore; Olivier Rixe; Axel Le Cesne; E Comoy; Thierry Le Chevalier
Ca125 and neuron-specific enolase (NSE) as tumour markers for intra-abdominal desmoplastic small round-cell tumours.
British journal of cancer 1997;75(1):76-8.
1996: Karim Fizazi; Axel Le Cesne; N Dohollou; S Affaied; Marc Spielmann; Thierry Le Chevalier
Serum neuron-specific enolase (NSE) as a tumour marker for the Ewing's sarcoma family of tumours.
European journal of cancer (Oxford, England : 1990) 1996;32A(10):1823-4.
1996: Karim Fizazi; J Feuillard; Axel Le Cesne; Philippe Terrier; M Raphael; P Pouillart; Thomas Tursz
Soft tissue sarcomas in HIV-infected adult patients.
European journal of cancer (Oxford, England : 1990) 1996;32A(10):1812-4.
1996: J Y Blay; F Chauvin; Axel Le Cesne; B Anglaret; D Bouhour; Christine Lasset; G Freyer; T Philip; Pierre Biron
Early lymphopenia after cytotoxic chemotherapy as a risk factor for febrile neutropenia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(2):636-43.
1995: Axel Le Cesne
[Chemotherapy of metastatic soft tissue sarcoma].
Presse médicale (Paris, France : 1983) 1995;24(26):1214-20.
1995: Axel Le Cesne; G Chabot; J Bérille; C Lucas; M Baud; Alain Gouyette; Michel Marty; Thierry Le Chevalier
Phase I-II and pharmacokinetic study of a new fotemustine schedule in advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 1995;13(1):69-78.
1995: Axel Le Cesne; E Antoine; Marc Spielmann; Thierry Le Chevalier; E Brain; C Toussaint; Nicolas Janin; L Kayitalire; F Fontaine; J Genin
High-dose ifosfamide: circumvention of resistance to standard-dose ifosfamide in advanced soft tissue sarcomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(7):1600-8.
1995: Axel Le Cesne; Thierry Le Chevalier; Rodrigo Arriagada
Impact of chemotherapy on survival in locally advanced non-small cell lung cancer: the Gustave-Roussy experience.
Lung cancer (Amsterdam, Netherlands) 1995;12 Suppl 1():S79-85.
1995: Axel Le Cesne; Thierry Le Chevalier; Rodrigo Arriagada
Dealing with initial chemotherapy doses: a new basis for treatment optimisation in limited small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1995;6 Suppl 3():S53-6.
1994: P Girard; P Baldeyrou; T Le Chevalier; Axel Le Cesne; A Brigandi; Dominique Grunenwald
Surgery for pulmonary metastases. Who are the 10-year survivors?
Cancer 1994;74(10):2791-7.
1994: Karim Fizazi; I Cojean; Axel Le Cesne; L Kayitalire; Thierry Le Chevalier; Thomas Tursz; Marc Spielmann
[Soft tissue sarcomas: general review].
Bulletin du cancer 1994;81(10):835-52.
1994: S Roithmann; Claudine Pique; Axel Le Cesne; Lélia Delamarre; Danielle Pham; Thomas Tursz; Marie-Christine Dokhélar
The open reading frame I (ORF I)/ORF II part of the human T-cell leukemia virus type I X region is dispensable for p40tax, p27rex, or envelope expression.
Journal of virology 1994;68(5):3448-51.
1991: Axel Le Cesne; Thierry Le Chevalier; P Caille; E Cvitkovic; Genevieve Contesso; Marc Spielmann; J Rouesse
[Metastases from cancers of unknown primary site. Data from 302 autopsies].
Presse médicale (Paris, France : 1983) 1991;20(29):1369-73.