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Michel Le Hir

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C C Berthier; C Pally; G Weckbecker; F Raulf; H Rehrauer; U Wagner; Michel Le Hir; H P Marti
Experimental heart transplantation: effect of cyclosporine on expression and activity of metzincins.
Brigitte Kaissling; Michel Le Hir
The renal cortical interstitium: morphological and functional aspects.
Nicolas Picard; Oliver Baum; Alexander Vogetseder; Brigitte Kaissling; Michel Le Hir
Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat.

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All Publications

2009: C C Berthier; C Pally; G Weckbecker; F Raulf; H Rehrauer; U Wagner; Michel Le Hir; H P Marti
Experimental heart transplantation: effect of cyclosporine on expression and activity of metzincins.
Swiss medical weekly 2009;139(15-16):233-40.
2008: Brigitte Kaissling; Michel Le Hir
The renal cortical interstitium: morphological and functional aspects.
Histochemistry and cell biology 2008;130(2):247-62.
2008: Nicolas Picard; Oliver Baum; Alexander Vogetseder; Brigitte Kaissling; Michel Le Hir
Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat.
Histochemistry and cell biology 2008;130(1):141-55.
2008: Alexander Vogetseder; Nicolas Picard; Ariana Gaspert; Michael Walch; Brigitte Kaissling; Michel Le Hir
Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells.
American journal of physiology. Cell physiology 2008;294(1):C22-8.
2007: Patricia R Wahl; Michel Le Hir; Alexander Vogetseder; Alexandre Arcaro; Astrid Starke; Ying Waeckerle-Men; Andreas L Serra; Rudolf P Wuthrich
Mitotic activation of Akt signalling pathway in Han:SPRD rats with polycystic kidney disease.
Nephrology (Carlton, Vic.) 2007;12(4):357-63.
2007: Franziska Theilig; Wilhelm Kriz; Timo Jerichow; Petra Schrade; Brunhilde Hähnel; Thomas E Willnow; Michel Le Hir; Sebastian Bachmann
Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury.
Journal of the American Society of Nephrology : JASN 2007;18(6):1824-34.
2007: Thomas Schmidt; Patricia Wahl; Rudolf P Wüthrich; Alexander Vogetseder; Nicolas Picard; Brigitte Kaissling; Michel Le Hir
Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture.
Histochemistry and cell biology 2007;127(2):123-9.
2007: Alexander Vogetseder; Thomas Palan; Desa Bacic; Brigitte Kaissling; Michel Le Hir
Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney.
American journal of physiology. Cell physiology 2007;292(2):C807-13.
2007: Ming Wu; Patricia R Wahl; Michel Le Hir; Ying Wackerle-Men; Rudolf P Wuthrich; Andreas L Serra
Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease.
Kidney & blood pressure research 2007;30(4):253-9.
2006: Patricia R Wahl; Andreas L Serra; Michel Le Hir; Klaus D Molle; Michael N Hall; Rudolf P Wüthrich
Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(3):598-604.
2005: Michel Le Hir; Brigitte Kaissling
Antibodies against macrophages that overlap in specificity with fibroblasts.
Kidney international 2005;68(5):2400; author reply 2400-1.
2005: Alexander Vogetseder; Adnan Karadeniz; Brigitte Kaissling; Michel Le Hir
Tubular cell proliferation in the healthy rat kidney.
Histochemistry and cell biology 2005;124(2):97-104.
2005: Michel Le Hir; Ivan Hegyi; Dominique Cueni-Loffing; Johannes Loffing; Brigitte Kaissling
Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys.
Histochemistry and cell biology 2005;123(4-5):335-46.
2004: Roland Schoop; Patricia Wahl; Michel Le Hir; Uwe Heemann; Minghui Wang; Rudolf P Wüthrich
Suppressed T-cell activation by IFN-gamma-induced expression of PD-L1 on renal tubular epithelial cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(11):2713-20.
2004: Valérie Besse-Eschmann; Michel Le Hir; Nicole Endlich; Karlhans Endlich
Alteration of podocytes in a murine model of crescentic glomerulonephritis.
Histochemistry and cell biology 2004;122(2):139-49.
2004: Michel Le Hir
Histopathology of humorally mediated anti-glomerular basement membrane (GBM) glomerulonephritis in mice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(7):1875-80.
2004: Marcus J Moeller; Abdulsalam Soofi; Inge Hartmann; Michel Le Hir; Roger C Wiggins; Wilhelm Kriz; Lawrence B Holzman
Podocytes populate cellular crescents in a murine model of inflammatory glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2004;15(1):61-7.
2003: Michel Le Hir; Valérie Besse-Eschmann
A novel mechanism of nephron loss in a murine model of crescentic glomerulonephritis.
Kidney international 2003;63(2):591-9.
2002: Valérie Besse-Eschmann; Jelena Klisic; Vera Nief; Michel Le Hir; Brigitte Kaissling; Patrice M Ambühl
Regulation of the proximal tubular sodium/proton exchanger NHE3 in rats with puromycin aminonucleoside (PAN)-induced nephrotic syndrome.
Journal of the American Society of Nephrology : JASN 2002;13(9):2199-206.
2002: Patricia Wahl; Roland Schoop; Grozdana Bilic; Jörg Neuweiler; Michel Le Hir; Steven K Yoshinaga; Rudolf P Wüthrich
Renal tubular epithelial expression of the costimulatory molecule B7RP-1 (inducible costimulator ligand).
Journal of the American Society of Nephrology : JASN 2002;13(6):1517-26.
2001: Michel Le Hir; C Keller; V Eschmann; Brunhilde Hähnel; Hiltraud Hosser; Wilhelm Kriz
Podocyte bridges between the tuft and Bowman's capsule: an early event in experimental crescentic glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2001;12(10):2060-71.
2001: M Bopst; IRENE GARCIA; Reto Guler; Maria L Olleros; T Rülicke; M Müller; S Wyss; Karl Frei; Michel Le Hir; Hans-Pietro Eugster
Differential effects of TNF and LTalpha in the host defense against M. bovis BCG.
European journal of immunology 2001;31(6):1935-43.
2001: Michel Le Hir; B Ryffel; U Schatzmann
IL-12-dependent, INF-gamma-independent experimental glomerulonephritis.
Kidney & blood pressure research 2001;24(1):27-32.
2000: JM Bonvini; U Schatzmann; Beatrice Beck-Schimmer; LK Sun; S R Rittling; D T Denhardt; Michel Le Hir; Rudolf P Wüthrich
Lack of in vivo function of osteopontin in experimental anti-GBM nephritis.
Journal of the American Society of Nephrology : JASN 2000;11(9):1647-55.
1999: Michel Le Hir; M Martin; C Haas
A syndrome resembling human systemic sclerosis (scleroderma) in MRL/lpr mice lacking interferon-gamma (IFN-gamma) receptor (MRL/lprgammaR-/-).
Clinical and experimental immunology 1999;115(2):281-7.
1999: U Schatzmann; C Haas; Michel Le Hir
A Th1 response is essential for induction of crescentic glomerulonephritis in mice.
Kidney & blood pressure research 1999;22(3):135-9.
1998: Bernhard RYFFEL; Hans-Pietro Eugster; C Haas; Michel Le Hir
Failure to induce anti-glomerular basement membrane glomerulonephritis in TNF alpha/beta deficient mice.
International journal of experimental pathology 1998;79(6):453-60.
1998: Michel Le Hir; C Haas; M Marino; Bernhard RYFFEL
Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice.
Laboratory investigation; a journal of technical methods and pathology 1998;78(12):1625-31.
1998: C Haas; Bernhard RYFFEL; Michel Le Hir
IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3713-8.
1998: Bernhard RYFFEL; Michel Le Hir; M Müller; Hans-Pietro Eugster
Correction of the TNF-LT alpha-deficient phenotype by bone marrow transplantation.
Developmental immunology 1998;6(3-4):253-60.
1997: C Haas; Bernhard RYFFEL; Michel Le Hir
IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5484-91.
1997: Bernhard RYFFEL; Franco E Di Padova; MH Schreier; Michel Le Hir; Hans-Pietro Eugster; Valerie QUESNIAUX
Lack of type 2 T cell-independent B cell responses and defect in isotype switching in TNF-lymphotoxin alpha-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2126-33.
1997: Michel Le Hir; Hans-Pietro Eugster
Absence of follicular dendritic cells (FDC) in mutant mice with deficient TNF/lymphotoxin (LT) signaling.
Advances in experimental medicine and biology 1997;417():487-91.
1996: Johannes Loffing; Dominique Loffing-Cueni; Ivan Hegyi; M R Kaplan; S C Hebert; Michel Le Hir; Brigitte Kaissling
Thiazide treatment of rats provokes apoptosis in distal tubule cells.
Kidney international 1996;50(4):1180-90.
1996: C Haas; Bruce D Car; Bernhard RYFFEL; Michel Le Hir
Lipopolysaccharide-induced glomerulonephritis develops in the absence of interferon-gamma signaling.
Experimental nephrology 1996;4(4):222-30.
1996: Michel Le Hir; H Bluethmann; M H Kosco-Vilbois; M Müller; F di Padova; M Moore; Bernhard RYFFEL; Hans-Pietro Eugster
Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling.
The Journal of experimental medicine 1996;183(5):2367-72.
1996: Brigitte Kaissling; Ivan Hegyi; Johannes Loffing; Michel Le Hir
Morphology of interstitial cells in the healthy kidney.
Anatomy and embryology 1996;193(4):303-18.
1996: M Müller; Hans-Pietro Eugster; Michel Le Hir; A Shakhov; F Di Padova; C Maurer; Valerie QUESNIAUX; Bernhard RYFFEL
Correction or transfer of immunodeficiency due to TNF-LT alpha deletion by bone marrow transplantation.
Molecular medicine (Cambridge, Mass.) 1996;2(2):247-55.
1996: Hans-Pietro Eugster; M Muller; U Karrer; Bruce D Car; Bruno Schnyder; V M Eng; G Woerly; Michel Le Hir; F di Padova; M Aguet; Rolf M Zinkernagel; H Bluethmann; Bernhard RYFFEL
Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice.
International immunology 1996;8(1):23-36.
1995: Johannes Loffing; Michel Le Hir; Brigitte Kaissling
Modulation of salt transport rate affects DNA synthesis in vivo in rat renal tubules.
Kidney international 1995;47(6):1615-23.
1995: K Mlodzik; Johannes Loffing; Michel Le Hir; Brigitte Kaissling
Ecto-5'-nucleotidase is expressed by pericytes and fibroblasts in the rat heart.
Histochemistry and cell biology 1995;103(3):227-36.
1995: C Haas; Bernhard RYFFEL; Michel Le Hir
Crescentic glomerulonephritis in interferon-gamma receptor deficient mice.
Journal of inflammation 1995;47(4):206-13.
1995: Michel Le Hir; H Bluethmann; M H Kosco-Vilbois; M Müller; F di Padova; M Moore; Bernhard RYFFEL; Hans-Pietro Eugster
Tumor necrosis factor receptor-1 signaling is required for differentiation of follicular dendritic cells, germinal center formation, and full antibody responses.
Journal of inflammation 1995;47(1-2):76-80.
1994: T C Schmid; Johannes Loffing; Michel Le Hir; Brigitte Kaissling
Distribution of ecto-5'-nucleotidase in the rat liver: effect of anaemia.
Histochemistry 1994;101(6):439-47.
1994: Stephan Holmer; B Rinne; Kai-Uwe Eckardt; Michel Le Hir; K Schricker; Brigitte Kaissling; Günter A J Riegger; Armin Kurtz
Role of renal nerves for the expression of renin in adult rat kidney.
The American journal of physiology 1994;266(5 Pt 2):F738-45.
1994: Brigitte Kaissling; Michel Le Hir
Characterization and distribution of interstitial cell types in the renal cortex of rats.
Kidney international 1994;45(3):709-20.
1994: J S Braun; Michel Le Hir; Brigitte Kaissling
Morphology and distribution of ecto-5'-nucleotidase-positive cells in the rat choroid plexus.
Journal of neurocytology 1994;23(3):193-200.
1993: J S Braun; Brigitte Kaissling; Michel Le Hir; W Zenker
Cellular components of the immune barrier in the spinal meninges and dorsal root ganglia of the normal rat: immunohistochemical (MHC class II) and electron-microscopic observations.
Cell and tissue research 1993;273(2):209-17.
1993: Brigitte Kaissling; S Spiess; B Rinne; Michel Le Hir
Effects of anemia on morphology of rat renal cortex.
The American journal of physiology 1993;264(4 Pt 2):F608-17.
1992: W Zenker; B Rinne; S Bankoul; Michel Le Hir; Brigitte Kaissling
5'-nucleotidase in spinal meningeal compartments in the rat. An immuno and enzyme histochemical study.
Histochemistry 1992;98(2):135-9.