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Nhat Le

Research Profile

Living Beings

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Chemicals & Drugs

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Publications

TOP 3
Alfia Khaibullina; Beom-Su Jang; Haihao Sun; Nhat Le; Sarah Yu; Victor Frenkel; Jorge Carrasquillo; Ira Pastan; King Li; Chang H Paik
Pulsed high-intensity focused ultrasound enhances uptake of radiolabeled monoclonal antibody to human epidermoid tumor in nude mice.
Hisataka Kobayashi; Yoshinori Koyama; Tristan Barrett; Yukihiro Hama; Celeste A S Regino; In Soo Shin; Beom-Su Jang; Nhat Le; Chang H Paik; Peter L Choyke; Yasuteru Urano
Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging.
Beom-Su Jang; Esther Lim; Seung Hee Park; In Soo Shin; S Narasimhan Danthi; In Sook Hwang; Nhat Le; Sarah Yu; Jianwu Xie; King Li; Jorge Carrasquillo; Chang H Paik
Radiolabeled high affinity peptidomimetic antagonist selectively targets alpha(v)beta(3) receptor-positive tumor in mice.

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All Publications

2008: Alfia Khaibullina; Beom-Su Jang; Haihao Sun; Nhat Le; Sarah Yu; Victor Frenkel; Jorge Carrasquillo; Ira Pastan; King Li; Chang H Paik
Pulsed high-intensity focused ultrasound enhances uptake of radiolabeled monoclonal antibody to human epidermoid tumor in nude mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(2):295-302.
2007: Hisataka Kobayashi; Yoshinori Koyama; Tristan Barrett; Yukihiro Hama; Celeste A S Regino; In Soo Shin; Beom-Su Jang; Nhat Le; Chang H Paik; Peter L Choyke; Yasuteru Urano
Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging.
ACS nano 2007;1(4):258-64.
2007: Beom-Su Jang; Esther Lim; Seung Hee Park; In Soo Shin; S Narasimhan Danthi; In Sook Hwang; Nhat Le; Sarah Yu; Jianwu Xie; King Li; Jorge Carrasquillo; Chang H Paik
Radiolabeled high affinity peptidomimetic antagonist selectively targets alpha(v)beta(3) receptor-positive tumor in mice.
Nuclear medicine and biology 2007;34(4):363-70.
2007: In Soo Shin; Beom-Su Jang; S Narasimhan Danthi; Jianwu Xie; Sarah Yu; Nhat Le; Jin-Soo Maeng; In Sook Hwang; King Li; Jorge Carrasquillo; Chang H Paik
Use of antibody as carrier of oligomers of peptidomimetic alphavbeta3 antagonist to target tumor-induced neovasculature.
Bioconjugate chemistry 2007;18(3):821-8.
2006: yujian zhang; Laiman Xiang; Raffit Hassan; Chang H Paik; Jorge Carrasquillo; Beom-Su Jang; Nhat Le; Mitchell Ho; Ira Pastan
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4695-701.
2002: Insook Kim; Hisataka Kobayashi; Tae M Yoo; Meyong-kon Kim; Nhat Le; Eui-sik Han; Qing-Cheng Wang; Ira Pastan; Jorge Carrasquillo; Chang H Paik
Lowering of pI by acylation improves the renal uptake of 99mTc-labeled anti-Tac dsFv: effect of different acylating reagents.
Nuclear medicine and biology 2002;29(8):795-801.
2000: Valeri N Karamychev; Igor G Panyutin; Meyoung-Kon Kim; Nhat Le; Chang H Paik; Jorge Carrasquillo; MW Reed; Ronald D Neumann
DNA cleavage by 111In-labeled oligodeoxyribonucleotides.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(6):1093-101.
2000: Hisataka Kobayashi; C H Kao; Robert J Kreitman; Nhat Le; Meyoung-Kon Kim; Martin W Brechbiel; Chang H Paik; Ira Pastan; Jorge Carrasquillo
Pharmacokinetics of 111In- and 125I-labeled antiTac single-chain Fv recombinant immunotoxin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(4):755-62.
2000: BF Sun; Hisataka Kobayashi; Nhat Le; Tae M Yoo; D Drumm; Chang H Paik; J G McAfee; Jorge Carrasquillo
Effects of insulinlike growth factor binding proteins on insulinlike growth factor-I biodistribution in tumor-bearing nude mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(2):318-26.
1999: Hisataka Kobayashi; BF Sun; Tae M Yoo; Nhat Le; Meyoung-Kon Kim; Chang H Paik; Ira Pastan; Thomas Waldmann; Jorge Carrasquillo
Methods to avoid adverse effect of circulating antigen on biodistribution of 125I-labeled antiTac dsFv: preinjection of intact antibody versus clearance of antigen with adivin-biotin system.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(8):1381-91.
1999: IS Kim; Tae M Yoo; Hisataka Kobayashi; Meyoung-Kon Kim; Nhat Le; Qing-Cheng Wang; Ira Pastan; Jorge Carrasquillo; Chang H Paik
Chemical modification to reduce renal uptake of disulfide-bonded variable region fragment of anti-Tac monoclonal antibody labeled with 99mTc.
Bioconjugate chemistry 1999;10(3):447-53.
1999: Hisataka Kobayashi; IS Kim; D Drumm; Meyoung-Kon Kim; David S Paik; Nhat Le; Thomas Waldmann; Jorge Carrasquillo; Chang H Paik
Favorable effects of glycolate conjugation on the biodistribution of humanized antiTac Fab fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(5):837-45.
1999: Jorge Carrasquillo; Jeffrey D White; Chang H Paik; Andrew Raubitschek; Nhat Le; M Rotman; Martin W Brechbiel; Otto A Gansow; Lois E Top; P Perentesis; James C Reynolds; David L Nelson; Thomas Waldmann
Similarities and differences in 111In- and 90Y-labeled 1B4M-DTPA antiTac monoclonal antibody distribution.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(2):268-76.
1999: Hisataka Kobayashi; Nhat Le; IS Kim; Meyoung-Kon Kim; Jae-Eun Pie; D Drumm; David S Paik; Thomas Waldmann; Chang H Paik; Jorge Carrasquillo
The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points.
Cancer research 1999;59(2):422-30.
1999: M Kim; Jurgen Seidel; Nhat Le; IS Kim; Tae M Yoo; C Barker; Hisataka Kobayashi; Michael V Green; Jorge Carrasquillo; Chang H Paik
Evaluation of 99mTc-mercaptoacetyltriglycine-biocytin as a new hepatobiliary imaging agent in mice coinjected with bilirubin.
Nuclear medicine and biology 1999;26(1):43-9.
1998: Hisataka Kobayashi; Eui-sik Han; IS Kim; Nhat Le; V Rajagopal; Robert J Kreitman; Ira Pastan; Chang H Paik; Jorge Carrasquillo
Similarities in the biodistribution of iodine-labeled anti-Tac single-chain disulfide-stabilized Fv fragment and anti-Tac disulfide-stabilized Fv fragment.
Nuclear medicine and biology 1998;25(4):387-93.
1998: Hisataka Kobayashi; BF Sun; Eui-sik Han; Meyoung-Kon Kim; Nhat Le; Qing-Cheng Wang; David L Nelson; Ira Pastan; Thomas Waldmann; Chang H Paik; Jorge Carrasquillo
Epitope blocking: positive and negative effects on the biodistribution of 125I-labeled anti-Tac disulfide-stabilized Fv fragment of two antibodies against different epitopes of the circulating antigen.
Japanese journal of cancer research : Gann 1998;89(4):436-44.
1997: BF Sun; Hisataka Kobayashi; Nhat Le; Tae M Yoo; D Drumm; Chang H Paik; J G McAfee; Jorge Carrasquillo
Biodistribution of 125I-labeled des(1-3) insulin-like growth factor I in tumor-bearing nude mice and its in vitro catabolism.
Cancer research 1997;57(13):2754-9.
1997: Hisataka Kobayashi; Tae M Yoo; D Drumm; Meyoung-Kon Kim; BF Sun; Nhat Le; KO Webber; Ira Pastan; Thomas Waldmann; Chang H Paik; Jorge Carrasquillo
Improved biodistribution of 125I-labeled anti-Tac disulfide-stabilized Fv fragment by blocking its binding to the alpha subunit of the interleukin 2 receptor in the circulation with preinjected humanized anti-Tac IgG.
Cancer research 1997;57(10):1955-61.
1997: Tae M Yoo; H K Chang; C W Choi; KO Webber; Nhat Le; IS Kim; William Eckelman; Ira Pastan; Jorge Carrasquillo; Chang H Paik
Technetium-99m labeling and biodistribution of anti-TAC disulfide-stabilized Fv fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(2):294-300.
1996: Hisataka Kobayashi; Tae M Yoo; IS Kim; Meyoung-Kon Kim; Nhat Le; KO Webber; Ira Pastan; Chang H Paik; William Eckelman; Jorge Carrasquillo
L-lysine effectively blocks renal uptake of 125I- or 99mTc-labeled anti-Tac disulfide-stabilized Fv fragment.
Cancer research 1996;56(16):3788-95.
1996: M C Chakrabarti; Nhat Le; Chang H Paik; W G De Graff; Jorge Carrasquillo
Prevention of radiolysis of monoclonal antibody during labeling.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(8):1384-8.
1995: C W Choi; Lixin Lang; J T Lee; KO Webber; Tae M Yoo; H K Chang; Nhat Le; Elaine M Jagoda; Chang H Paik; Ira Pastan
Biodistribution of 18F- and 125I-labeled anti-Tac disulfide-stabilized Fv fragments in nude mice with interleukin 2 alpha receptor-positive tumor xenografts.
Cancer research 1995;55(22):5323-9.
1995: T Saga; Ronald D Neumann; T Heya; J Sato; S Kinuya; Nhat Le; Chang H Paik; John N Weinstein
Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8999-9003.
1995: M B Moreno; J A Titus; MS Cole; JY Tso; Nhat Le; Chang H Paik; T Bakács; C M Zacharchuk; David M Segal; John R Wunderlich
Bispecific antibodies retarget murine T cell cytotoxicity against syngeneic breast cancer in vitro and in vivo.
Cancer immunology, immunotherapy : CII 1995;40(3):182-90.
1994: T Saga; John N Weinstein; J M Jeong; T Heya; J T Lee; Nhat Le; Chang H Paik; Cynthia Sung; Ronald D Neumann
Two-step targeting of experimental lung metastases with biotinylated antibody and radiolabeled streptavidin.
Cancer research 1994;54(8):2160-5.
1993: CS John; T Saga; S Kinuya; Nhat Le; J M Jeong; Chang H Paik; Richard C Reba; V M Varma; J G McAfee
An improved synthesis of [125I]N-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanoma.
Nuclear medicine and biology 1993;20(1):75-9.
1992: Chang H Paik; V K Sood; Nhat Le; L Cioloca; Jorge Carrasquillo; James C Reynolds; Ronald D Neumann; Richard C Reba
Radiolabeled products in rat liver and serum after administration of antibody-amide-DTPA-indium-111.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(5):517-22.

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