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Thanh Le

Research Profile

Chemicals & Drugs

Disorders

Muscular Atrophy, Spinal

Anatomy

Phenomena

Living Beings

Procedures

Co-author Network

Publications

TOP 3
Le thi Hao; heidi Fuller; Le Thanh Lam; Thanh T Le; Arthur H M Burghes; Glenn E Morris
Absence of gemin5 from SMN complexes in nuclear Cajal bodies.
Aarti Sharma; Anja Lambrechts; Le Thi Hao; Thanh T Le; Caroline A Sewry; Christophe Ampe; Arthur H M Burghes; Glenn E Morris
A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells.
Thanh T Le; Lan T Pham; Matthew E R Butchbach; Honglai L Zhang; Umrao R Monani; Daniel D Coovert; Tatiana O Gavrilina; Lei Xing; Gary J. Bassell; Arthur H M Burghes
SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.

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All Publications

2007: Le thi Hao; heidi Fuller; Le Thanh Lam; Thanh T Le; Arthur H M Burghes; Glenn E Morris
Absence of gemin5 from SMN complexes in nuclear Cajal bodies.
BMC cell biology 2007;8():28.
2005: Aarti Sharma; Anja Lambrechts; Le Thi Hao; Thanh T Le; Caroline A Sewry; Christophe Ampe; Arthur H M Burghes; Glenn E Morris
A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells.
Experimental cell research 2005;309(1):185-97.
2005: Thanh T Le; Lan T Pham; Matthew E R Butchbach; Honglai L Zhang; Umrao R Monani; Daniel D Coovert; Tatiana O Gavrilina; Lei Xing; Gary J. Bassell; Arthur H M Burghes
SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.
Human molecular genetics 2005;14(6):845-57.
2003: Umrao R Monani; Matthew T Pastore; Tatiana O Gavrilina; Sibylle Jablonka; Thanh T Le; Catia Andreassi; Jennifer M DiCocco; Christian L Lorson; Elliot J Androphy; Michael Sendtner; Michael Podell; Arthur H M Burghes
A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.
The Journal of cell biology 2003;160(1):41-52.
2001: Philip Young; Thanh T Le; M Dunckley; T M Nguyen; Arthur H M Burghes; Glenn E Morris
Nuclear gems and Cajal (coiled) bodies in fetal tissues: nucleolar distribution of the spinal muscular atrophy protein, SMN.
Experimental cell research 2001;265(2):252-61.
2000: Philip Young; Nguyen Thi Man; Christian L Lorson; Thanh T Le; Elliot J Androphy; Arthur H M Burghes; Glenn E Morris
The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding.
Human molecular genetics 2000;9(19):2869-77.
2000: Thanh T Le; Daniel D Coovert; Umrao R Monani; Glenn E Morris; Arthur H M Burghes
The survival motor neuron (SMN) protein: effect of exon loss and mutation on protein localization.
Neurogenetics 2000;3(1):7-16.
2000: Daniel D Coovert; Thanh T Le; Glenn E Morris; Nguyen Thi Man; M Kralewski; Michael Sendtner; Arthur H M Burghes
Does the survival motor neuron protein (SMN) interact with Bcl-2?
Journal of medical genetics 2000;37(7):536-9.
2000: R J Bartlett; S Stockinger; M M Denis; W T Bartlett; Luca Inverardi; Thanh T Le; Nguyen thi Man; Glenn E Morris; Daniel J Bogan; J Metcalf-Bogan; Joe Kornegay
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide.
Nature biotechnology 2000;18(6):615-22.
2000: Philip Young; Thanh T Le; Nguyen thi Man; Arthur H M Burghes; Glenn E Morris
The relationship between SMN, the spinal muscular atrophy protein, and nuclear coiled bodies in differentiated tissues and cultured cells.
Experimental cell research 2000;256(2):365-74.
2000: Umrao R Monani; Michael Sendtner; Daniel D Coovert; DONALD PARSONS; Catia Andreassi; Thanh T Le; Sibylle Jablonka; B Schrank; wilfried rossoll; W Rossol; Thomas W Prior; Glenn E Morris; Arthur H M Burghes
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Human molecular genetics 2000;9(3):333-9.
1999: Payam Mohaghegh; NR Rodrigues; N Owen; Chris P Ponting; Thanh T Le; Arthur H M Burghes; Kay E Davies
Analysis of mutations in the tudor domain of the survival motor neuron protein SMN.
European journal of human genetics : EJHG 1999;7(5):519-25.
1997: Daniel D Coovert; Thanh T Le; PE McAndrew; J Strasswimmer; Thomas Crawford; Jerry R Mendell; S E Coulson; Elliot J Androphy; Thomas W Prior; Arthur H M Burghes
The survival motor neuron protein in spinal muscular atrophy.
Human molecular genetics 1997;6(8):1205-14.