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Yingying Le

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Keqiang Chen; Scott Durum; Ji-Liang Gao; Wanghua Gong; Yingying Le; Mingyong Liu; Ying Liu; Philip M Murphy; Wei Shen; Chunyan Wang; Teizo Yoshimura; Ji Ming Wang
Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis.
Keqiang Chen; Yingying Le; Ying Liu; Wanghua Gong; Guoguang Ying; Jian Huang; Teizo Yoshimura; Lino Tessarollo; Ji Ming Wang
A critical role for the g protein-coupled receptor mFPR2 in airway inflammation and immune responses.
Jian Huang; Keqiang Chen; Wanghua Gong; Ye Zhou; Yingying Le; Xiuwu Bian; Ji Ming Wang
Receptor "hijacking" by malignant glioma cells: a tactic for tumor progression.

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2013: Keqiang Chen; Scott Durum; Ji-Liang Gao; Wanghua Gong; Yingying Le; Mingyong Liu; Ying Liu; Philip M Murphy; Wei Shen; Chunyan Wang; Teizo Yoshimura; Ji Ming Wang
Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis.
The Journal of clinical investigation 2013;123(4):1694-704.
2010: Keqiang Chen; Yingying Le; Ying Liu; Wanghua Gong; Guoguang Ying; Jian Huang; Teizo Yoshimura; Lino Tessarollo; Ji Ming Wang
A critical role for the g protein-coupled receptor mFPR2 in airway inflammation and immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(7):3331-5.
2008: Jian Huang; Keqiang Chen; Wanghua Gong; Ye Zhou; Yingying Le; Xiuwu Bian; Ji Ming Wang
Receptor "hijacking" by malignant glioma cells: a tactic for tumor progression.
Cancer letters 2008;267(2):254-61.
2005: Ye Zhou; Xiuwu Bian; Yingying Le; Wanghua Gong; Jinyue Hu; Xia Zhang; Lihua Wang; Pablo Iribarren; Rosalba Salcedo; O M Zack Howard; William Farrar; Ji Ming Wang
Formylpeptide receptor FPR and the rapid growth of malignant human gliomas.
Journal of the National Cancer Institute 2005;97(11):823-35.
2005: Yingying Le; Richard D Ye; Wanghua Gong; Jianxiang Li; Pablo Iribarren; Ji Ming Wang
Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis.
The FEBS journal 2005;272(3):769-78.
2005: Pablo Iribarren; Ye Zhou; Jinyue Hu; Yingying Le; Ji Ming Wang
Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in Alzheimer disease.
Immunologic research 2005;31(3):165-76.
2004: Yingying Le; Pablo Iribarren; Ye Zhou; Wanghua Gong; Jinyue Hu; Xia Zhang; Ji Ming Wang
Silencing the formylpeptide receptor FPR by short-interfering RNA.
Molecular pharmacology 2004;66(4):1022-8.
2004: Yingying Le; Pablo Iribarren; Wanghua Gong; Youhong Cui; Xia Zhang; Ji Ming Wang
TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):962-8.
2004: Guoguang Ying; Pablo Iribarren; Ye Zhou; Wanghua Gong; Ning Zhang; Zu-Xi Yu; Yingying Le; Youhong Cui; Ji Ming Wang
Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7078-85.
2004: Yingying Le; Ye Zhou; Pablo Iribarren; Jiming Wang
Chemokines and chemokine receptors: their manifold roles in homeostasis and disease.
Cellular & molecular immunology 2004;1(2):95-104.
2004: Heng Yi Tao; Chun Fu Wu; Ye Zhou; Wang Hua Gong; Xia Zhang; Pablo Iribarren; Yu Qing Zhao; Yingying Le; Ji Ming Wang
The grape component resveratrol interferes with the function of chemoattractant receptors on phagocytic leukocytes.
Cellular & molecular immunology 2004;1(1):50-6.
2003: Pablo Iribarren; You-Hong Cui; Yingying Le; Guoguang Ying; Xia Zhang; Wanghua Gong; Ji Ming Wang
IL-4 down-regulates lipopolysaccharide-induced formyl peptide receptor 2 in murine microglial cells by inhibiting the activation of mitogen-activated protein kinases.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5482-8.
2003: Yingying Le; Youhong Cui; Guoguang Ying; Pablo Iribarren; Ji Ming Wang
The role of chemokine receptors in the promotion of viral infections.
Contributions to microbiology 2003;10():210-31.
2002: Yingying Le; Philip M Murphy; Ji Ming Wang
Formyl-peptide receptors revisited.
Trends in immunology 2002;23(11):541-8.
2002: You-Hong Cui; Yingying Le; Xia Zhang; Wanghua Gong; K Abe; R Sun; J Van Damme; P Proost; Ji Ming Wang
Up-regulation of FPR2, a chemotactic receptor for amyloid beta 1-42 (A beta 42), in murine microglial cells by TNF alpha.
Neurobiology of disease 2002;10(3):366-77.
2002: Pablo Iribarren; You-Hong Cui; Yingying Le; Ji Ming Wang
The role of dendritic cells in neurodegenerative diseases.
Archivum immunologiae et therapiae experimentalis 2002;50(3):187-96.
2002: Yingying Le; Youhong Cui; Pablo Iribarren; Guoguang Ying; Ji Ming Wang
Manipulating chemoattractant and receptor genes.
In vivo (Athens, Greece) 2002;16(1):1-23.
2002: Yingying Le; Yiming Yang; Youhong Cui; Hiroshi Yazawa; Wanghua Gong; Cunping Qiu; Ji Ming Wang
Receptors for chemotactic formyl peptides as pharmacological targets.
International immunopharmacology 2002;2(1):1-13.
2002: You-Hong Cui; Yingying Le; Wanghua Gong; Paul Proost; Jo Van Damme; William Murphy; Ji Ming Wang
Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):434-42.
2001: H Yazawa; Z X Yu; Yingying Le; Wanghua Gong; V J Ferrans; Joost J Oppenheim; C C Li; Ji Ming Wang
Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2454-62.
2001: J Y Hu; Yingying Le; Wanghua Gong; NM Dunlop; Ji-Liang Gao; Philip M Murphy; Ji Ming Wang
Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1.
Journal of leukocyte biology 2001;70(1):155-61.
2001: Yingying Le; Michele A Wetzel; W Shen; Wanghua Gong; Thomas J Rogers; Earl E Henderson; Ji Ming Wang
Desensitization of chemokine receptor CCR5 in dendritic cells at the early stage of differentiation by activation of formyl peptide receptors.
Clinical immunology (Orlando, Fla.) 2001;99(3):365-72.
2001: B Q Li; Michele A Wetzel; Judy A Mikovits; Earl E Henderson; Thomas J Rogers; Wanghua Gong; Yingying Le; Francis W Ruscetti; Ji Ming Wang
The synthetic peptide WKYMVm attenuates the function of the chemokine receptors CCR5 and CXCR4 through activation of formyl peptide receptor-like 1.
Blood 2001;97(10):2941-7.
2001: De Yang; Q Chen; Yingying Le; Ji Ming Wang; Joost J Oppenheim
Differential regulation of formyl peptide receptor-like 1 expression during the differentiation of monocytes to dendritic cells and macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):4092-8.
2001: Yingying Le; Joost J Oppenheim; Ji Ming Wang
Pleiotropic roles of formyl peptide receptors.
Cytokine & growth factor reviews 2001;12(1):91-105.
2001: Yingying Le; H Yazawa; Wanghua Gong; Z Yu; V J Ferrans; Philip M Murphy; Ji Ming Wang
The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1448-51.
2001: Yingying Le; Wanghua Gong; HL Tiffany; Alexei Tumanov; Sergei A Nedospasov; W Shen; NM Dunlop; Ji-Liang Gao; Philip M Murphy; Joost J Oppenheim; Ji Ming Wang
Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(2):RC123.
2000: Yingying Le; J Hu; Wanghua Gong; W Shen; B Li; NM Dunlop; D O Halverson; Donald G Blair; Ji Ming Wang
Expression of functional formyl peptide receptors by human astrocytoma cell lines.
Journal of neuroimmunology 2000;111(1-2):102-8.
2000: W Shen; B Li; Michele A Wetzel; Thomas J Rogers; Earl E Henderson; SB Su; Wanghua Gong; Yingying Le; R Sargeant; D S Dimitrov; Joost J Oppenheim; Ji Ming Wang
Down-regulation of the chemokine receptor CCR5 by activation of chemotactic formyl peptide receptor in human monocytes.
Blood 2000;96(8):2887-94.
2000: Yingying Le; B Li; Wanghua Gong; W Shen; J Hu; NM Dunlop; Joost J Oppenheim; Ji Ming Wang
Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors.
Immunological reviews 2000;177():185-94.
2000: Yingying Le; S Jiang; J Hu; Wanghua Gong; S Su; NM Dunlop; W Shen; B Li; J Ming Wang
N36, a synthetic N-terminal heptad repeat domain of the HIV-1 envelope protein gp41, is an activator of human phagocytes.
Clinical immunology (Orlando, Fla.) 2000;96(3):236-42.
2000: W Shen; P Proost; B Li; Wanghua Gong; Yingying Le; R Sargeant; Philip M Murphy; J Van Damme; Ji Ming Wang
Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines.
Biochemical and biophysical research communications 2000;272(1):276-83.
2000: Yingying Le; Wanghua Gong; W Shen; B Li; NM Dunlop; Ji Ming Wang
A burgeoning family of biological mediators: chemokines and chemokine receptors.
Archivum immunologiae et therapiae experimentalis 2000;48(3):143-50.
1999: Yingying Le; Wanghua Gong; B Li; NM Dunlop; W Shen; SB Su; Richard D Ye; Ji Ming Wang
Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6777-84.
1999: Yingying Le; W Shen; B Li; Wanghua Gong; NM Dunlop; Ji Ming Wang
A new insight into the role of "old" chemotactic peptide receptors FPR and FPRL1: down-regulation of chemokine receptors CCR5 and CXCR4.
Forum (Genoa, Italy) 1999;9(4):299-314.