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Steven Leach

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Yue J Wang; Meritxell Rovira; Jennifer M Bailey; Steven D Leach
Sphere-forming assays for assessment of benign and malignant pancreatic stem cells.
Anirban Maitra; Steven D Leach
Disputed paternity: the uncertain ancestry of pancreatic ductal neoplasia.
Elayne Provost; Karen A Wehner; Xiangang Zhong; Foram Ashar; Rachel Green; Elizabeth Nguyen; MICHAEL PARSONS; Steven D Leach
Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development.

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All Publications

2013: Yue J Wang; Meritxell Rovira; Jennifer M Bailey; Steven D Leach
Sphere-forming assays for assessment of benign and malignant pancreatic stem cells.
Methods in molecular biology (Clifton, N.J.) 2013;980():281-90.
2012: Anirban Maitra; Steven D Leach
Disputed paternity: the uncertain ancestry of pancreatic ductal neoplasia.
Cancer cell 2012;22(6):701-3.
2012: Elayne Provost; Karen A Wehner; Xiangang Zhong; Foram Ashar; Rachel Green; Elizabeth Nguyen; MICHAEL PARSONS; Steven D Leach
Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development.
Development (Cambridge, England) 2012;139(17):3232-41.
2012: Megan H Cleveland; Jan Jensen; Solomon Afelik; Jacob M Sawyer; Steven D Leach
Exocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cells.
Seminars in cell & developmental biology 2012;23(6):711-9.
2012: Sayumi Yamazoe; Steven D Leach; Elayne Provost; Ilya A Shestopalov; James Kenneth Chen
Cyclic caged morpholinos: conformationally gated probes of embryonic gene function.
Angewandte Chemie (International ed. in English) 2012;51(28):6908-11.
2012: Tai-Chung Huang; Min-Sik Kim; Steven D Leach; LUIGI MARCHIONNI; Jonathan M Peterson; Nandini A Sahasrabuddhe; GUANG WILLIAM WONG; Yi Yang; Raghothama Chaerkady; Derese Getnet; Bidyut Ghosh; Akhilesh Pandey
Regulation of lipid metabolism by Dicer revealed through SILAC mice.
Journal of proteome research 2012;11(4):2193-205.
2012: Andrew D Rhim; Anil K Rustgi; Robert H Vonderheide; Nicole M Aiello; Jennifer M Bailey; Gregory L Beatty; Steven D Leach; Anirban Maitra; Florencia McAllister; Emily T Mirek; Maximilian Reichert; Ben Z Stanger
EMT and dissemination precede pancreatic tumor formation.
Cell 2012;148(1-2):349-61.
2011: Bidyut Ghosh; Steven D Leach
p53: Guardian of pancreatic epithelial identity.
Cell cycle (Georgetown, Tex.) 2011;10(11):1717.
2011: Shu Liu; Steven D Leach
Screening pancreatic oncogenes in zebrafish using the Gal4/UAS system.
Methods in cell biology 2011;105():367-81.
2011: Shu Liu; Steven D Leach
Zebrafish models for cancer.
Annual review of pathology 2011;6():71-93.
2010: Oliver A Kent; Raghu R Chivukula; Michael Mullendore; Erik A Wentzel; Georg Feldmann; Kwang H Lee; Shu Liu; Steven D Leach; Anirban Maitra; Joshua T Mendell
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway.
Genes & development 2010;24(24):2754-9.
2010: Meritxell Rovira; Sherri-Gae Scott; Andrew S Liss; Jan Jensen; Sarah P Thayer; Steven D Leach
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):75-80.
2010: Oscar K Serrano; Muhammad A Chaudhry; Steven D Leach
The role of PET scanning in pancreatic cancer.
Advances in surgery 2010;44():313-25.
2009: Steven D Leach
Pisces and cancer: the stars align.
Zebrafish 2009;6(4):317.
2009: Melanie P Wescott; Meritxell Rovira; Maximilian Reichert; Johannes von Burstin; Anna Means; Steven D Leach; Anil K Rustgi
Pancreatic ductal morphogenesis and the Pdx1 homeodomain transcription factor.
Molecular biology of the cell 2009;20(22):4838-44.
2009: MICHAEL PARSONS; Harshan Pisharath; Shamila Yusuff; John C Moore; Arndt F Siekmann; Nathan Lawson; Steven D Leach
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas.
Mechanisms of development 2009;126(10):898-912.
2009: Kotaro Hama; Elayne Provost; Timothy C Baranowski; Amy L Rubinstein; Jennifer L Anderson; Steven D Leach; Steven A Farber
In vivo imaging of zebrafish digestive organ function using multiple quenched fluorescent reporters.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(2):G445-53.
2008: Nils Habbe; Guanglu Shi; Robert A Meguid; Volker Fendrich; Farzad Esni; Huiping Chen; Georg Feldmann; Doris A Stoffers; Stephen F Konieczny; Steven D Leach; Anirban Maitra
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(48):18913-8.
2008: Siân Jones; Xiaosong Zhang; DONALD PARSONS; Jimmy Cheng-Ho Lin; Rebecca J Leary; Philipp Angenendt; Parminder Mankoo; Hannah Carter; Hirohiko Kamiyama; Antonio Jimeno; Seung-Mo Hong; BAOJIN FU; Ming-Tseh Lin; Eric S Calhoun; Mihoko Kamiyama; Kimberly Walter; Tatiana Nikolskaya; Yuri Nikolsky; James Hartigan; Douglas R Smith; Manuel Hidalgo; Steven D Leach; Alison P Klein; Elizabeth M Jaffee; Michael Goggins; Anirban Maitra; Christine A Iacobuzio-Donahue; James R Eshleman; Scott E Kern; Ralph Hruban; Rachel Karchin; Nickolas Papadopoulos; Giovanni Parmigiani; Bert Vogelstein; Victor E Velculescu; Kenneth W Kinzler
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
Science (New York, N.Y.) 2008;321(5897):1801-6.
2008: Volker Fendrich; Farzad Esni; Maria Veronica R Garay; Georg Feldmann; Nils Habbe; Jan Jensen; Yuval Dor; Doris A Stoffers; Jan Jensen; Steven D Leach; Anirban Maitra
Hedgehog signaling is required for effective regeneration of exocrine pancreas.
Gastroenterology 2008;135(2):621-31.
2008: Seung Woo Park; Jon M Davison; Jerry Rhee; Ralph Hruban; Anirban Maitra; Steven D Leach
Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas.
Gastroenterology 2008;134(7):2080-90.
2008: P Duc Si Dong; Elayne Provost; Steven D Leach; Didier Y R Stainier
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas.
Genes & development 2008;22(11):1445-50.
2008: Jacqueline M Garonzik Wang; Steven D Leach
Truncal sarcomas and abdominal desmoids.
The Surgical clinics of North America 2008;88(3):571-82, vi-vii.
2008: Marnie E Halpern; Jerry Rhee; Mary Goll; Courtney M Akitake; MICHAEL PARSONS; Steven D Leach
Gal4/UAS transgenic tools and their application to zebrafish.
Zebrafish 2008;5(2):97-110.
2008: Jon M Davison; Seung Woo Park; Jerry M Rhee; Steven D Leach
Characterization of Kras-mediated pancreatic tumorigenesis in zebrafish.
Methods in enzymology 2008;438():391-417.
2007: Stephen F Konieczny; Steven D Leach
Metaplastic metamorphoses in the mammalian pancreas.
Gastroenterology 2007;133(6):2056-9.
2007: Leanne Godinho; Philip R Williams; Yvonne Claassen; Elayne Provost; Steven D Leach; Maarten Kamermans; Rachel O L Wong
Nonapical symmetric divisions underlie horizontal cell layer formation in the developing retina in vivo.
Neuron 2007;56(4):597-603.
2007: Elayne Provost; Jerry Rhee; Steven D Leach
Viral 2A peptides allow expression of multiple proteins from a single ORF in transgenic zebrafish embryos.
Genesis (New York, N.Y. : 2000) 2007;45(10):625-9.
2007: Jon M Davison; Courtney M Akitake; Mary Goll; Jerry M Rhee; Nathan Gosse; Herwig Baier; Marnie E Halpern; Steven D Leach; MICHAEL PARSONS
Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish.
Developmental biology 2007;304(2):811-24.
2007: Zeina H Jarikji; Sandeep Vanamala; Caroline W Beck; Chris V E Wright; Steven D Leach; Marko E Horb
Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas.
Developmental biology 2007;304(2):786-99.
2007: Sandra A Biankin; Michael I Collector; Andrew V Biankin; Lindsey J Brown; Wolfram Kleeberger; Wendy L Devereux; Cynthia A Zahnow; Stephen B Baylin; DAVID WATKINS; Saul J Sharkis; Steven D Leach
A histological survey of green fluorescent protein expression in 'green' mice: implications for stem cell research.
Pathology 2007;39(2):247-51.
2007: Biva M Desai; Jennifer Oliver-Krasinski; Diva D De Leon; Cyrus Farzad; Nankang Hong; Steven D Leach; Doris A Stoffers
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration.
The Journal of clinical investigation 2007;117(4):971-7.
2007: Lewis C. Murtaugh; Steven D Leach
A case of mistaken identity? Nonductal origins of pancreatic "ductal" cancers.
Cancer cell 2007;11(3):211-3.
2007: Harshan Pisharath; Jerry M Rhee; Michelle A Swanson; Steven D Leach; MICHAEL PARSONS
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase.
Mechanisms of development 2007;124(3):218-29.
2007: James M Wells; Farzad Esni; Gregory P Boivin; Bruce Aronow; William Stuart; Chelsea Combs; Angela Sklenka; Steven D Leach; Andrew M Lowy
Wnt/beta-catenin signaling is required for development of the exocrine pancreas.
BMC developmental biology 2007;7():4.
2006: Bidyut Ghosh; Steven D Leach
Interactions between hairy/enhancer of split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex.
The Biochemical journal 2006;393(Pt 3):679-85.
2005: Leanne Godinho; Jeff S. Mumm; Philip R Williams; Eric H Schroeter; Amy Koerber; Seung W Park; Steven D Leach; Rachel O L Wong
Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina.
Development (Cambridge, England) 2005;132(22):5069-79.
2005: Anna L Means; Ingrid M Meszoely; Kazufumi Suzuki; Yoshiharu Miyamoto; Anil K Rustgi; Robert J Coffey; Christopher V E Wright; Doris A Stoffers; Steven D Leach
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates.
Development (Cambridge, England) 2005;132(16):3767-76.
2005: Noriyoshi Fukushima; Jens Koopmann; Norihiro Sato; Nijaguna B Prasad; Ralph Carvalho; Steven D Leach; Ralph Hruban; Michael Goggins
Gene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(6):779-87.
2005: Sachiyo Nomura; Stephen H Settle; Charles M Leys; Anna L Means; Richard M Peek; Steven D Leach; Christopher V E Wright; Robert J Coffey; James R Goldenring
Evidence for repatterning of the gastric fundic epithelium associated with Ménétrier's disease and TGFalpha overexpression.
Gastroenterology 2005;128(5):1292-305.
2005: Karen L Tedesco; Jordan Berlin; Charles D Blanke; Ming Teng; Hak Choy; John Roberts; R Daniel Beauchamp; Steven D Leach; Ken Wyman; John L Tarpley; Yu Shyr; Carol Caillouette; Bapsi Chakravarthy
Phase I trial of Orzel (UFT plus leucovorin), cisplatin, and radiotherapy in the treatment of potentially resectable esophageal cancer.
International journal of radiation oncology, biology, physics 2005;61(5):1364-70.
2005: Steven D Leach
Epithelial differentiation in pancreatic development and neoplasia: new niches for nestin and Notch.
Journal of clinical gastroenterology 2005;39(4 Suppl 2):S78-82.
2005: Donna E Hansel; Anirban Maitra; John W Lin; Michael Goggins; Pedram Argani; Charles J Yeo; Steven Piantadosi; Steven D Leach; Andrew V Biankin
Expression of the caudal-type homeodomain transcription factors CDX 1/2 and outcome in carcinomas of the ampulla of Vater.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(9):1811-8.
2005: Nijaguna B Prasad; Andrew V Biankin; Noriyoshi Fukushima; Anirban Maitra; Surajit Dhara; Abdel G Elkahloun; Ralph Hruban; Michael Goggins; Steven D Leach
Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.
Cancer research 2005;65(5):1619-26.
2005: Farzad Esni; Yoshiharu Miyamoto; Steven D Leach; Bidyut Ghosh
Primary explant cultures of adult and embryonic pancreas.
Methods in molecular medicine 2005;103():259-71.
2004: Noriyoshi Fukushima; Norihiro Sato; Nijaguna B Prasad; Steven D Leach; Ralph Hruban; Michael Goggins
Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays.
Oncogene 2004;23(56):9042-51.
2004: John W Lin; Andrew V Biankin; Marko E Horb; Bidyut Ghosh; Nijaguna B Prasad; Nelson S Yee; Michael Pack; Steven D Leach
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.
Developmental biology 2004;274(2):491-503.
2004: Farzad Esni; Bidyut Ghosh; Andrew V Biankin; John W Lin; Megan A Albert; Xiaobing Yu; Raymond J MacDonald; Curt I Civin; Francisco X Real; Michael Pack; Douglas W Ball; Steven D Leach
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas.
Development (Cambridge, England) 2004;131(17):4213-24.
2004: John W Lin; Andrew V Biankin; Marko E Horb; Bidyut Ghosh; Nijaguna B Prasad; Nelson S Yee; Michael Pack; Steven D Leach
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas.
Developmental biology 2004;270(2):474-86.
2004: Michael G House; Charles J Yeo; John L Cameron; Kurtis A Campbell; Richard D Schulick; Steven D Leach; Ralph Hruban; Karen M Horton; elliot fishman; Keith D Lillemoe
Predicting resectability of periampullary cancer with three-dimensional computed tomography.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2004;8(3):280-8.
2004: Steven D Leach
Mouse models of pancreatic cancer: the fur is finally flying!
Cancer cell 2004;5(1):7-11.
2004: Farzad Esni; Doris A Stoffers; Toshiyuki Takeuchi; Steven D Leach
Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas.
Mechanisms of development 2004;121(1):15-25.
2003: Yoshiharu Miyamoto; Anirban Maitra; Bidyut Ghosh; Ulrich Zechner; Pedram Argani; Christine A Iacobuzio-Donahue; Virote Sriuranpong; Tatsuya Iso; Ingrid M Meszoely; Michael S Wolfe; Ralph Hruban; Douglas W Ball; Roland M Schmid; Steven D Leach
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis.
Cancer cell 2003;3(6):565-76.
2003: Jeffrey M Hardacre; Christine A Iacobuzio-Donahue; Taylor A Sohn; Susan C Abraham; Charles J Yeo; Keith D Lillemoe; Michael A Choti; Kurtis A Campbell; Richard D Schulick; Ralph Hruban; John L Cameron; Steven D Leach
Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis.
Annals of surgery 2003;237(6):853-8; discussion 858-9.
2003: Anna L Means; Kevin C Ray; Amar B Singh; M Kay Washington; Robert H Whitehead; Raymond C Harris; Christopher V E Wright; Robert J Coffey; Steven D Leach
Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia.
Gastroenterology 2003;124(4):1020-36.
2003: Susan C Abraham; Steven D Leach; Charles J Yeo; John L Cameron; Linda A Murakata; John K Boitnott; Jorge Albores-Saavedra; Ralph Hruban
Eosinophilic pancreatitis and increased eosinophils in the pancreas.
The American journal of surgical pathology 2003;27(3):334-42.
2003: John W Lin; Steven D Leach
Current treatment of gastric cancer: is adjuvant therapy of benefit?
Advances in surgery 2003;37():95-121.
2003: Douglas W Ball; Steven D Leach
Notch in malignancy.
Cancer treatment and research 2003;115():95-121.
2002: Theresa Pluth Yeo; Ralph Hruban; Steven D Leach; Robb E Wilentz; Taylor A Sohn; Scott E Kern; Christine A Iacobuzio-Donahue; Anirban Maitra; Michael Goggins; Marcia Canto; Ross A. Abrams; Daniel Laheru; Elizabeth M Jaffee; Manuel Hidalgo; Charles J Yeo
Pancreatic cancer.
Current problems in cancer 2002;26(4):176-275.
2002: Martin Wagner; Christoph K Weber; Frank Bressau; Florian R Greten; Volker Stagge; Matthias Ebert; Steven D Leach; Guido Adler; Roland M Schmid
Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells.
Gastroenterology 2002;122(7):1898-912.
2002: Howard C Crawford; Charles R Scoggins; M Kay Washington; Lynn M Matrisian; Steven D Leach
Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas.
The Journal of clinical investigation 2002;109(11):1437-44.
2001: Pedram Argani; Christine A Iacobuzio-Donahue; Byungwoo Ryu; Christophe Rosty; Michael Goggins; Robb E Wilentz; S R Murugesan; Steven D Leach; Elizabeth M Jaffee; Charles J Yeo; John L Cameron; Scott E Kern; Ralph Hruban
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(12):3862-8.
2001: Ingrid M Meszoely; Anna L Means; Charles R Scoggins; Steven D Leach
Developmental aspects of early pancreatic cancer.
Cancer journal (Sudbury, Mass.) 2001;7(4):242-50.
2001: Pedram Argani; Christophe Rosty; Robert E Reiter; Robb E Wilentz; S R Murugesan; Steven D Leach; Byungwoo Ryu; Halcyon Skinner; Michael Goggins; Elizabeth M Jaffee; Charles J Yeo; John L Cameron; Scott E Kern; Ralph Hruban
Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma.
Cancer research 2001;61(11):4320-4.
2001: Anna L Means; Steven D Leach
Lineage commitment and cellular differentiation in exocrine pancreas.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2001;1(6):587-96.
2001: Charles D Blanke; M Stipanov; J Morrow; M Rothenberg; Rebecca Chinery; Yu Shyr; R Coffey; D H Johnson; Steven D Leach; R Daniel Beauchamp
A phase I study of vitamin E, 5-fluorouracil and leucovorin for advanced malignancies.
Investigational new drugs 2001;19(1):21-7.
2000: Charles R Scoggins; Ingrid M Meszoely; M Wada; Anna L Means; L Yang; Steven D Leach
p53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(4):G827-36.
2000: Howard Mertz; P Sechopoulos; Dominique Delbeke; Steven D Leach
EUS, PET, and CT scanning for evaluation of pancreatic adenocarcinoma.
Gastrointestinal endoscopy 2000;52(3):367-71.
2000: S Y Song; Ingrid M Meszoely; Robert J Coffey; Jennifer A Pietenpol; Steven D Leach
K-Ras-independent effects of the farnesyl transferase inhibitor L-744,832 on cyclin B1/Cdc2 kinase activity, G2/M cell cycle progression and apoptosis in human pancreatic ductal adenocarcinoma cells.
Neoplasia (New York, N.Y.) 2000;2(3):261-72.
1999: S Y Song; M Gannon; M Kay Washington; Charles R Scoggins; Ingrid M Meszoely; James R Goldenring; C R Marino; E P Sandgren; Robert J Coffey; Christopher V E Wright; Steven D Leach
Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha.
Gastroenterology 1999;117(6):1416-26.
1999: Dominique Delbeke; DM Rose; William C Chapman; C Wright Pinson; J Kelly Wright; R Daniel Beauchamp; Y Shyr; Steven D Leach
Optimal interpretation of FDG PET in the diagnosis, staging and management of pancreatic carcinoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(11):1784-91.
1999: Charles R Scoggins; Ingrid M Meszoely; Charles D Blanke; R Daniel Beauchamp; Steven D Leach
Nonoperative management of primary colorectal cancer in patients with stage IV disease.
Annals of surgical oncology 1999;6(7):651-7.
1999: Andrew M Lowy; Steven D Leach
Adjuvant/neoadjuvant chemoradiation for gastric and pancreatic cancer.
Oncology (Williston Park, N.Y.) 1999;13(10 Suppl 5):121-30.
1999: Richard J Bold; Chusilp Charnsangavej; Karen R Cleary; M Jennings; A Madray; Steven D Leach; James L Abbruzzese; Peter W T Pisters; Jeffrey E Lee; Douglas B Evans
Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 1999;3(3):233-43.
1999: DM Rose; Dominique Delbeke; R Daniel Beauchamp; William C Chapman; Martin P Sandler; Kenneth W Sharp; William O Richards; J Kelly Wright; M E Frexes; C Wright Pinson; Steven D Leach
18Fluorodeoxyglucose-positron emission tomography in the management of patients with suspected pancreatic cancer.
Annals of surgery 1999;229(5):729-37; discussion 737-8.
1999: Charles D Blanke; Hak Choy; Ming Teng; R Daniel Beauchamp; Steven D Leach; J Roberts; K Washington; D H Johnson
Concurrent paclitaxel and thoracic irradiation for locally advanced esophageal cancer.
Seminars in radiation oncology 1999;9(2 Suppl 1):43-52.
1999: Andrew M Lowy; Paul F Mansfield; Steven D Leach; R Pazdur; P Dumas; Jaffer A Ajani
Response to neoadjuvant chemotherapy best predicts survival after curative resection of gastric cancer.
Annals of surgery 1999;229(3):303-8.
1999: ZOE STEWART; Steven D Leach; Jennifer A Pietenpol
p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption.
Molecular and cellular biology 1999;19(1):205-15.
1998: CD Scatena; ZOE STEWART; Deborah J Mays; Luo Jia Tang; Christopher Jay Keefer; Steven D Leach; Jennifer A Pietenpol
Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest.
The Journal of biological chemistry 1998;273(46):30777-84.
1998: Steven D Leach; CD Scatena; Christopher Jay Keefer; H A Goodman; S Y Song; L Yang; Jennifer A Pietenpol
Negative regulation of Wee1 expression and Cdc2 phosphorylation during p53-mediated growth arrest and apoptosis.
Cancer research 1998;58(15):3231-6.
1998: Steven D Leach; Jeffrey E Lee; Chusilp Charnsangavej; Karen R Cleary; Andrew M Lowy; CJ Fenoglio; Peter W T Pisters; Douglas B Evans
Survival following pancreaticoduodenectomy with resection of the superior mesenteric-portal vein confluence for adenocarcinoma of the pancreatic head.
The British journal of surgery 1998;85(5):611-7.
1998: Steven D Leach; D H Berger; BS Davidson; Steven A Curley; Michael A Tainsky
Enhanced Krev-1 expression inhibits the growth of pancreatic adenocarcinoma cells.
Pancreas 1998;16(4):491-8.
1998: Ingrid M Meszoely; W C Chapman; Michael D Holzman; Steven D Leach
New trends in gastrointestinal surgical oncology.
Cancer treatment and research 1998;98():239-91.
1997: Kelly M McMasters; Todd M Tuttle; Steven D Leach; tyvin rich; Karen R Cleary; D B Evans; S A Curley
Neoadjuvant chemoradiation for extrahepatic cholangiocarcinoma.
American journal of surgery 1997;174(6):605-8; discussion 608-9.
1997: J L Abbruzzese; D B Evans; Isaac Raijman; L Larry; T King; Steven D Leach; M L Frazier
Detection of mutated c-Ki-ras in the bile of patients with pancreatic cancer.
Anticancer research 1997;17(2A):795-801.
1996: Frank A Sinicrope; Douglas B Evans; Steven D Leach; Karen R Cleary; CJ Fenoglio; J Jack Lee; James L Abbruzzese
bcl-2 and p53 expression in resectable pancreatic adenocarcinomas: association with clinical outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(12):2015-22.
1996: Andrew M Lowy; Paul F Mansfield; Steven D Leach; Jaffer A Ajani
Laparoscopic staging for gastric cancer.
Surgery 1996;119(6):611-4.
1996: Steven D Leach; B S Davidson; Frederick C Ames; Douglas B Evans
Alternative method for exposure of the retropancreatic mesenteric vasculature during total pancreatectomy.
Journal of surgical oncology 1996;61(2):163-5.
1996: George M Fuhrman; Steven D Leach; CA Staley; J C Cusack; Chusilp Charnsangavej; Karen R Cleary; A K El-Naggar; CJ Fenoglio; Jeffrey E Lee; Douglas B Evans
Rationale for en bloc vein resection in the treatment of pancreatic adenocarcinoma adherent to the superior mesenteric-portal vein confluence. Pancreatic Tumor Study Group.
Annals of surgery 1996;223(2):154-62.
1996: Douglas B Evans; Jeffrey E Lee; Steven D Leach; George M Fuhrman; J C Cusack; tyvin rich
Vascular resection and intraoperative radiation therapy during pancreaticoduodenectomy: rationale and technique.
Advances in surgery 1996;29():235-62.
1995: Steven D Leach; J A Rose; Andrew M Lowy; Jeffrey E Lee; C Charnsangavej; James L Abbruzzese; Ruth Katz; Douglas B Evans
Significance of peritoneal cytology in patients with potentially resectable adenocarcinoma of the pancreatic head.
Surgery 1995;118(3):472-8.
1995: Steven D Leach; Andrew M Lowy; Paul F Mansfield; Jaffer A Ajani
Adjuvant therapy for resectable gastric adenocarcinoma: preoperative and postoperative chemotherapy trials.
The Journal of infusional chemotherapy 1995;5(3):104-11.
1994: Steven D Leach; Irvin M Modlin; L Goldstein; G H Ballantyne
Laparoscopic local excision of a proximal rectal carcinoid.
Journal of laparoendoscopic surgery 1994;4(1):65-70.
1993: C R Marino; Steven D Leach; J F Schaefer; L J Miller; Fred S Gorelick
Characterization of cAMP-dependent protein kinase activation by CCK in rat pancreas.
FEBS letters 1993;316(1):48-52.
1993: Steven D Leach; A J Bilchik; O Karapetian; Fred S Gorelick; Irvin M Modlin
Influence of chloroquine on diet-induced pancreatitis.
Pancreas 1993;8(1):64-9.
1992: Fred S Gorelick; Irvin M Modlin; Steven D Leach; R Carangelo; M Katz
Intracellular proteolysis of pancreatic zymogens.
The Yale journal of biology and medicine 1992;65(5):407-20; discussion 437-40.
1992: Steven D Leach; Fred S Gorelick; Irvin M Modlin
New perspectives on acute pancreatitis.
Scandinavian journal of gastroenterology. Supplement 1992;192():29-38.
1991: Steven D Leach; Irvin M Modlin; G A Scheele; Fred S Gorelick
Intracellular activation of digestive zymogens in rat pancreatic acini. Stimulation by high doses of cholecystokinin.
The Journal of clinical investigation 1991;87(1):362-6.
1990: Steven D Leach; Fred S Gorelick; Irvin M Modlin
Acute pancreatitis at its centenary. The contribution of Reginald Fitz.
Annals of surgery 1990;212(1):109-13.
1990: A J Bilchik; Steven D Leach; KA Zucker; Irvin M Modlin
Experimental models of acute pancreatitis.
The Journal of surgical research 1990;48(6):639-47.
1990: Steven D Leach; A I LaMorte; L D True; Stuart D Flynn; P E Schwartz; C E Cahow; Barbara K Kinder
Aberrant hormone production from ovarian neoplasms: strategies for diagnosis and therapy.
World journal of surgery 1990;14(3):335-40; discussion 340-1.
1989: Steven D Leach; G H Meier; Richard J Gusberg
Endoscopic sclerotherapy: a risk factor for splanchnic venous thrombosis.
Journal of vascular surgery 1989;10(1):9-12; discussion 12-3.
1988: Steven D Leach; A L Toole; H Stern; R W DeNatale; M D Tilson
Effect of beta-adrenergic blockade on the growth rate of abdominal aortic aneurysms.
Archives of surgery (Chicago, Ill. : 1960) 1988;123(5):606-9.