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David Leader

Research Profile

Chemicals & Drugs

Living Beings

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Phosphorylation

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Cloning, Molecular

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Publications

TOP 3
Scott W Robinson; Julian A T Dow; Pawel Herzyk; David P Leader
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster.
David P Leader; E James Milner-White
Structure Motivator: a tool for exploring small three-dimensional elements in proteins.
David P Leader; Karl Burgess; Darren Creek; Michael P Barrett
Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry.

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All Publications

2013: Scott W Robinson; Julian A T Dow; Pawel Herzyk; David P Leader
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster.
Nucleic acids research 2013;41(Database issue):D744-50.
2012: David P Leader; E James Milner-White
Structure Motivator: a tool for exploring small three-dimensional elements in proteins.
BMC structural biology 2012;12():26.
2011: David P Leader; Karl Burgess; Darren Creek; Michael P Barrett
Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry.
Rapid communications in mass spectrometry : RCM 2011;25(22):3422-6.
2011: David P Leader; E James Milner-White
The structure of the ends of α-helices in globular proteins: effect of additional hydrogen bonds and implications for helix formation.
Proteins 2011;79(3):1010-9.
2009: Gilleain M Torrance; David P Leader; David R Gilbert; E James Milner-White
A novel main chain motif in proteins bridged by cationic groups: the niche.
Journal of molecular biology 2009;385(4):1076-86.
2009: David P Leader; E James Milner-White
Motivated proteins: a web application for studying small three-dimensional protein motifs.
BMC bioinformatics 2009;10():60.
2004: Ela Hunt; Neil Hanlon; David P Leader; Hunter Bryce; Anna F Dominiczak
The visual language of synteny.
Omics : a journal of integrative biology 2004;8(4):289-305.
2004: David P Leader
BugView: a browser for comparing genomes.
Bioinformatics (Oxford, England) 2004;20(1):129-30.
2000: N G Brown; G Beaud; G Hardie; David P Leader
Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R.
BMC biochemistry 2000;1():2.
1999: KA Powell; L C Campbell; J M Tavaré; David P Leader; J A Wakefield; Gwyn W Gould
Trafficking of Glut4-green fluorescent protein chimaeras in 3T3-L1 adipocytes suggests distinct internalization mechanisms regulating cell surface glut4 levels.
The Biochemical journal 1999;344 Pt 2():535-43.
1997: C McInnes; David P Leader
Tissue-specific distribution of mouse casein kinase I alpha mRNA.
DNA sequence : the journal of DNA sequencing and mapping 1997;8(1-2):55-7.
1995: David P Leader; B Peter; B Ehmer
Analysis of CpG dinucleotide frequency in relationship to translational reading frame suggests a class of genes in which mutation of this dinucleotide is asymmetric with respect to DNA strand.
FEBS letters 1995;376(3):125-9.
1991: David P Leader; A D Deana; F Marchiori; F C Purves; L A Pinna
Further definition of the substrate specificity of the alpha-herpesvirus protein kinase and comparison with protein kinases A and C.
Biochimica et biophysica acta 1991;1091(3):426-31.
1990: G Zhang; David P Leader
The structure of the pseudorabies virus genome at the end of the inverted repeat sequences proximal to the junction with the short unique region.
The Journal of general virology 1990;71 ( Pt 10)():2433-41.
1990: J Munro; D G Campbell; David P Leader
The activity of protein kinases from hamster fibroblasts towards a synthetic peptide based on a carboxy-terminal portion of ribosomal protein S6.
Biochimica et biophysica acta 1990;1054(2):225-30.
1990: G Zhang; R Stevens; David P Leader
The protein kinase encoded in the short unique region of pseudorabies virus: description of the gene and identification of its product in virions and in infected cells.
The Journal of general virology 1990;71 ( Pt 8)():1757-65.
1988: C McInnes; David P Leader
The tropomyosin mRNAs of mouse striated muscles: molecular cloning of beta-tropomyosin.
Biochimica et biophysica acta 1988;951(1):117-22.
1988: B Peter; Y M Man; C E Begg; I Gall; David P Leader
Mouse cytoskeletal gamma-actin: analysis and implications of the structure of cloned cDNA and processed pseudogenes.
Journal of molecular biology 1988;203(3):665-75.
1988: C E Begg; H Delius; David P Leader
Duplicated region of the mouse genome containing a cytoplasmic gamma-actin processed pseudogene associated with long interspersed repetitive elements.
Journal of molecular biology 1988;203(3):677-87.
1988: David P Leader; F C Purves
The herpesvirus protein kinase: a new departure in protein phosphorylation?
Trends in biochemical sciences 1988;13(7):244-6.
1988: David P Leader; M Katan
Viral aspects of protein phosphorylation.
The Journal of general virology 1988;69 ( Pt 7)():1441-64.
1987: T Jakubowicz; David P Leader
Activation of a ribosomal protein S6 kinase in mouse fibroblasts during infection with herpesvirus.
European journal of biochemistry / FEBS 1987;168(2):371-6.
1987: M C Frame; F C Purves; Duncan J McGeoch; Howard S Marsden; David P Leader
Identification of the herpes simplex virus protein kinase as the product of viral gene US3.
The Journal of general virology 1987;68 ( Pt 10)():2699-704.
1987: F C Purves; M Katan; David P Leader
Complete purification of the pseudorabies virus protein kinase.
European journal of biochemistry / FEBS 1987;167(3):507-12.
1987: F C Purves; R M Longnecker; David P Leader; B Roizman
Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture.
Journal of virology 1987;61(9):2896-901.
1987: Y M Man; H Delius; David P Leader
Molecular analysis of elements inserted into mouse gamma-actin processed pseudogenes.
Nucleic acids research 1987;15(8):3291-304.
1987: T Jakubowicz; David P Leader
A major phosphoprotein of cells infected with pseudorabies virus is phosphorylated by cellular casein kinase II.
The Journal of general virology 1987;68 ( Pt 4)():1159-63.
1987: T Jakubowicz; David P Leader
Induction, partial purification and characterization of a hamster fibroblast protein kinase activity that phosphorylates ribosomal protein S6.
European journal of biochemistry / FEBS 1987;164(1):83-8.
1986: F C Purves; A D Deana; F Marchiori; David P Leader; L A Pinna
The substrate specificity of the protein kinase induced in cells infected with herpesviruses: studies with synthetic substrates [corrected] indicate structural requirements distinct from other protein kinases.
Biochimica et biophysica acta 1986;889(2):208-15.
1986: M Katan; M J McGarvey; W S Stevely; David P Leader
The phosphorylation of ribosomal protein S6 by protein kinases from cells infected with pseudorabies virus.
The Biochemical journal 1986;239(1):205-11.
1986: David P Leader; I Gall; P C Campbell
The structure of a cDNA clone corresponding to mouse cardiac muscle actin mRNA.
Bioscience reports 1986;6(8):741-7.
1986: David P Leader; I Gall; P Campbell; A M Frischauf
Isolation and characterization of cDNA clones from mouse skeletal muscle actin mRNA.
DNA (Mary Ann Liebert, Inc.) 1986;5(3):235-8.
1986: F C Purves; M Katan; W S Stevely; David P Leader
Characteristics of the induction of a new protein kinase in cells infected with herpesviruses.
The Journal of general virology 1986;67 ( Pt 6)():1049-57.
1986: J Munro; R H Burdon; David P Leader
Characterization of a human orphon 28 S ribosomal DNA.
Gene 1986;48(1):65-70.
1985: M Katan; W S Stevely; David P Leader
Partial purification and characterization of a new phosphoprotein kinase from cells infected with pseudorabies virus.
European journal of biochemistry / FEBS 1985;152(1):57-65.
1985: P J Parker; M Katan; M D Waterfield; David P Leader
The phosphorylation of eukaryotic ribosomal protein S6 by protein kinase C.
European journal of biochemistry / FEBS 1985;148(3):579-86.
1985: W S Stevely; M Katan; V Stirling; G Smith; David P Leader
Protein kinase activities associated with the virions of pseudorabies and herpes simplex virus.
The Journal of general virology 1985;66 ( Pt 4)():661-73.
1985: David P Leader; I Gall; H Lehrach
The structure of a cloned mouse gamma-actin processed pseudogene.
Gene 1985;36(3):369-74.
1984: I M Kennedy; David P Leader; W S Stevely
The phosphorylation of ribosomal protein S6 in hamster fibroblasts infected with pseudorabies virus inactivated by ultraviolet radiation.
The Journal of general virology 1984;65 ( Pt 9)():1621-4.
1984: I M Kennedy; R H Burdon; David P Leader
Heat shock causes diverse changes in the phosphorylation of the ribosomal proteins of mammalian cells.
FEBS letters 1984;169(2):267-73.
1983: M J McGarvey; David P Leader
The ribosomal proteins phosphorylated in vitro by protein kinase activities from Krebs II ascites cells.
Bioscience reports 1983;3(7):621-9.
1981: I M Kennedy; W S Stevely; David P Leader
Phosphorylation of ribosomal proteins in hamster fibroblasts infected with pseudorabies virus or herpes simplex virus.
Journal of virology 1981;39(2):359-66.
1981: I M Kennedy; David P Leader
Increased phosphorylation of ribosomal protein S6 in hamster fibroblasts transformed by polyoma virus and simian virus 40.
The Biochemical journal 1981;198(1):235-7.
1980: I M Kennedy; David P Leader
The phosphorylation of protein S6 in the newly-synthesized cytoplasmic ribosomes of hamster fibroblasts.
Molecular biology reports 1980;6(4):199-202.