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Alexander Leaf

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TOP 3
Barry London; Christine Albert; Mark E Anderson; Wayne R Giles; David Van Wagoner; Ethan Balk; George E Billman; Mei Chung; William Lands; Alexander Leaf; John McAnulty; Jeffrey R Martens; Rebecca B Costello; David Austin Lathrop
Omega-3 fatty acids and cardiac arrhythmias: prior studies and recommendations for future research: a report from the National Heart, Lung, and Blood Institute and Office Of Dietary Supplements Omega-3 Fatty Acids and their Role in Cardiac Arrhythmogenesis Workshop.
Alexander Leaf
Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids.
Alexander Leaf
Omega-3 fatty acids and prevention of arrhythmias.

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2007: Barry London; Christine Albert; Mark E Anderson; Wayne R Giles; David Van Wagoner; Ethan Balk; George E Billman; Mei Chung; William Lands; Alexander Leaf; John McAnulty; Jeffrey R Martens; Rebecca B Costello; David Austin Lathrop
Omega-3 fatty acids and cardiac arrhythmias: prior studies and recommendations for future research: a report from the National Heart, Lung, and Blood Institute and Office Of Dietary Supplements Omega-3 Fatty Acids and their Role in Cardiac Arrhythmogenesis Workshop.
Circulation 2007;116(10):e320-35.
2007: Alexander Leaf
Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids.
Journal of cardiovascular medicine (Hagerstown, Md.) 2007;8 Suppl 1():S27-9.
2007: Alexander Leaf
Omega-3 fatty acids and prevention of arrhythmias.
Current opinion in lipidology 2007;18(1):31-4.
2006: Alexander Leaf
Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids.
Fundamental & clinical pharmacology 2006;20(6):525-38.
2006: Yong-Fu Xiao; Li Ma; Sho-Ya Wang; Mark E Josephson; Ging Kuo Wang; James P Morgan; Alexander Leaf
Potent block of inactivation-deficient Na+ channels by n-3 polyunsaturated fatty acids.
American journal of physiology. Cell physiology 2006;290(2):C362-70.
2005: Alexander Leaf
Do n-3 polyunsaturated fatty acids prevent atrial fibrillation after coronary artery bypass grafting surgery?
Nature clinical practice. Cardiovascular medicine 2005;2(12):626-7.
2005: Alexander Leaf; Christine M Albert; Mark Josephson; David Steinhaus; Jeffrey Kluger; Jing X Kang; Benjamin Cox; Hui Zhang; David Schoenfeld
Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake.
Circulation 2005;112(18):2762-8.
2005: Alexander Leaf; Yong-Fu Xiao; Jing X Kang; George E Billman
Membrane effects of the n-3 fish oil fatty acids, which prevent fatal ventricular arrhythmias.
The Journal of membrane biology 2005;206(2):129-39.
2005: Alexander Leaf; Jing X Kang; Yong-Fu Xiao
Omega-3 fatty acids and ventricular arrhythmias.
World review of nutrition and dietetics 2005;94():129-38.
2004: Yong-Fu Xiao; Qingen Ke; Yu Chen; James P Morgan; Alexander Leaf
Inhibitory effect of n-3 fish oil fatty acids on cardiac Na+/Ca2+ exchange currents in HEK293t cells.
Biochemical and biophysical research communications 2004;321(1):116-23.
2003: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman
Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils.
Circulation 2003;107(21):2646-52.
2003: Alexander Leaf; Yong-Fu Xiao; Jing X Kang; George E Billman
Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids.
Pharmacology & therapeutics 2003;98(3):355-77.
2002: Alexander Leaf; Yong-Fu Xiao; Jing X Kang
Interactions of n-3 fatty acids with ion channels in excitable tissues.
Prostaglandins, leukotrienes, and essential fatty acids 2002;67(2-3):113-20.
2002: Alexander Leaf
Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids.
Nutrition and health 2002;16(1):47-9.
2001: Alexander Leaf; Yong-Fu Xiao
The modulation of ionic currents in excitable tissues by n-3 polyunsaturated fatty acids.
The Journal of membrane biology 2001;184(3):263-71.
2001: Zhao B Kang; Yinlin Ge; Zhihong Chen; Joanne E Cluette-Brown; Michael Laposata; Alexander Leaf; Jing X Kang
Adenoviral gene transfer of Caenorhabditis elegans n--3 fatty acid desaturase optimizes fatty acid composition in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4050-4.
2001: Yong-Fu Xiao; Qingen Ke; Sho-Ya Wang; K Auktor; Yinke Yang; Ging Kuo Wang; James P Morgan; Alexander Leaf
Single point mutations affect fatty acid block of human myocardial sodium channel alpha subunit Na+ channels.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3606-11.
2001: E M Pound; Jing X Kang; Alexander Leaf
Partitioning of polyunsaturated fatty acids, which prevent cardiac arrhythmias, into phospholipid cell membranes.
Journal of lipid research 2001;42(3):346-51.
2001: Yong-Fu Xiao; Qingen Ke; Sho-Ya Wang; Yinke Yang; Ging Kuo Wang; James P Morgan; Alexander Leaf
Point mutations in alpha-subunit of human cardiac Na+ channels alter Na+ current kinetics.
Biochemical and biophysical research communications 2001;281(1):45-52.
2001: Alexander Leaf
Electrophysiologic basis for the antiarrhythmic and anticonvulsant effects of omega 3 polyunsaturated fatty acids.
World review of nutrition and dietetics 2001;88():72-8.
2001: Alexander Leaf
The electrophysiologic basis for the antiarrhythmic and anticonvulsant effects of n-3 polyunsaturated fatty acids: heart and brain.
Lipids 2001;36 Suppl():S107-10.
2001: Alexander Leaf; Jing X Kang
Omega-3 fatty acids and cardiovascular disease.
World review of nutrition and dietetics 2001;89():161-72.
2001: Alexander Leaf
Diet and sudden cardiac death.
The journal of nutrition, health & aging 2001;5(3):173-8.
2000: Yong-Fu Xiao; SN Wright; Ging Kuo Wang; James P Morgan; Alexander Leaf
Coexpression with beta(1)-subunit modifies the kinetics and fatty acid block of hH1(alpha) Na(+) channels.
American journal of physiology. Heart and circulatory physiology 2000;279(1):H35-46.
2000: Jing X Kang; Alexander Leaf
Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids.
The American journal of clinical nutrition 2000;71(1 Suppl):202S-7S.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman; Rob A Voskuyl
The antiarrhythmic and anticonvulsant effects of dietary N-3 fatty acids.
The Journal of membrane biology 1999;172(1):1-11.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman; Rob A Voskuyl
Experimental studies on antiarrhythmic and antiseizure effects of polyunsaturated fatty acids in excitable tissues.
The Journal of nutritional biochemistry 1999;10(8):440-8.
1999: George E Billman; Jing X Kang; Alexander Leaf
Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs.
Circulation 1999;99(18):2452-7.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman; Rob A Voskuyl
Functional and electrophysiologic effects of polyunsaturated fatty acids on exictable tissues: heart and brain.
Prostaglandins, leukotrienes, and essential fatty acids 1999;60(5-6):307-12.
1999: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman
n-3 fatty acids in the prevention of cardiac arrhythmias.
Lipids 1999;34 Suppl():S187-9.
1998: Jing X Kang; J Bell; Alexander Leaf; RL Beard; RA Chandraratna
Retinoic acid alters the intracellular trafficking of the mannose-6-phosphate/insulin-like growth factor II receptor and lysosomal enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13687-91.
1998: Yong-Fu Xiao; SN Wright; Ging Kuo Wang; James P Morgan; Alexander Leaf
Fatty acids suppress voltage-gated Na+ currents in HEK293t cells transfected with the alpha-subunit of the human cardiac Na+ channel.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2680-5.
1998: Alexander Leaf; Jing X Kang; Yong-Fu Xiao; George E Billman
Dietary n-3 fatty acids in the prevention of cardiac arrhythmias.
Current opinion in clinical nutrition and metabolic care 1998;1(2):225-8.
1998: Rob A Voskuyl; M Vreugdenhil; Jing X Kang; Alexander Leaf
Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model.
European journal of pharmacology 1998;341(2-3):145-52.
1997: Jing X Kang; Y Li; Alexander Leaf
Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13671-6.
1997: George E Billman; Jing X Kang; Alexander Leaf
Prevention of ischemia-induced cardiac sudden death by n-3 polyunsaturated fatty acids in dogs.
Lipids 1997;32(11):1161-8.
1997: Y Li; Jing X Kang; Alexander Leaf
Differential effects of various eicosanoids on the production or prevention of arrhythmias in cultured neonatal rat cardiac myocytes.
Prostaglandins 1997;54(2):511-30.
1997: Yong-Fu Xiao; Ana Gomez; James P Morgan; William Lederer; Alexander Leaf
Suppression of voltage-gated L-type Ca2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4182-7.
1997: Jing X Kang; Ying Li; Alexander Leaf
Regulation of sodium channel gene expression by class I antiarrhythmic drugs and n - 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2724-8.
1997: Alexander Leaf; Jing X Kang
Dietary n-3 fatty acids in the prevention of lethal cardiac arrhythmias.
Current opinion in lipidology 1997;8(1):4-6.
1996: Martin Vreugdenhil; C Bruehl; Rob A Voskuyl; Jing X Kang; Alexander Leaf; Wytse J Wadman
Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12559-63.
1996: Jing X Kang; Alexander Leaf
Antiarrhythmic effects of polyunsaturated fatty acids. Recent studies.
Circulation 1996;94(7):1774-80.
1996: K H Weylandt; Jing X Kang; Alexander Leaf
Polyunsaturated fatty acids exert antiarrhythmic actions as free acids rather than in phospholipids.
Lipids 1996;31(9):977-82.
1996: Alexander Leaf; Jing X Kang
Prevention of cardiac sudden death by N-3 fatty acids: a review of the evidence.
Journal of internal medicine 1996;240(1):5-12.
1996: Jing X Kang; Alexander Leaf
Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3542-6.
1996: Jing X Kang; Alexander Leaf
The cardiac antiarrhythmic effects of polyunsaturated fatty acid.
Lipids 1996;31 Suppl():S41-4.
1996: Jing X Kang; Alexander Leaf
Protective effects of free polyunsaturated fatty acids on arrhythmias induced by lysophosphatidylcholine or palmitoylcarnitine in neonatal rat cardiac myocytes.
European journal of pharmacology 1996;297(1-2):97-106.
1995: Jing X Kang; Alexander Leaf
Protective effects of All-trans-retinoic acid against cardiac arrhythmias induced by isoproterenol, lysophosphatidylcholine or ischemia and reperfusion.
Journal of cardiovascular pharmacology 1995;26(6):943-8.
1995: Yong-Fu Xiao; Jing X Kang; James P Morgan; Alexander Leaf
Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11000-4.
1995: Jing X Kang; Yong-Fu Xiao; Alexander Leaf
Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(9):3997-4001.
1995: Jing X Kang; Alexander Leaf
Prevention and termination of beta-adrenergic agonist-induced arrhythmias by free polyunsaturated fatty acids in neonatal rat cardiac myocytes.
Biochemical and biophysical research communications 1995;208(2):629-36.
1995: Alexander Leaf
Omega-3 fatty acids and prevention of ventricular fibrillation.
Prostaglandins, leukotrienes, and essential fatty acids 1995;52(2-3):197-8.
1994: Alexander Leaf; Michael B Jorgensen; Alice K Jacobs; G Cote; David Schoenfeld; J Scheer; B H Weiner; J D Slack; M A Kellett; A E Raizner
Do fish oils prevent restenosis after coronary angioplasty?
Circulation 1994;90(5):2248-57.
1994: Salvatore Pepe; Konstantin Y Bogdanov; H Hallaq; Harold A Spurgeon; Alexander Leaf; Edward G Lakatta
Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8832-6.
1994: Ralph Witzgall; E O'Leary; Alexander Leaf; D Onaldi; Joseph V Bonventre
The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4514-8.
1994: George E Billman; H Hallaq; Alexander Leaf
Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4427-30.
1994: Alexander Leaf
Some effects of omega 3 fatty acids on coronary heart disease.
World review of nutrition and dietetics 1994;76():1-8.
1993: Alexander Leaf
Nutrition and fitness in health and disease. Implementation and mobilization of resources.
World review of nutrition and dietetics 1993;72():61-7.
1992: Alexander Leaf; H A Hallaq
The role of nutrition in the functioning of the cardiovascular system.
Nutrition reviews 1992;50(12):402-6.
1992: H Hallaq; T W Smith; Alexander Leaf
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1760-4.
1992: Alexander Leaf
The role of omega 3 fatty acids in the prevention and rehabilitation of coronary artery disease.
Annals of the Academy of Medicine, Singapore 1992;21(1):132-6.
1991: C D Malis; Alexander Leaf; G S Varadarajan; J B Newell; P C Weber; Thomas Force; Joseph V Bonventre
Effects of dietary omega 3 fatty acids on vascular contractility in preanoxic and postanoxic aortic rings.
Circulation 1991;84(3):1393-401.
1991: H Hallaq; Alexander Leaf
Effects of omega 3 and omega 6 polyunsaturated fatty acids on the action of cardiac glycosides on cultured rat myocardial cells.
World review of nutrition and dietetics 1991;66():250-4.
1990: C D Malis; P C Weber; Alexander Leaf; Joseph V Bonventre
Incorporation of marine lipids into mitochondrial membranes increases susceptibility to damage by calcium and reactive oxygen species: evidence for enhanced activation of phospholipase A2 in mitochondria enriched with n-3 fatty acids.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8845-9.
1990: H Hallaq; A Sellmayer; T W Smith; Alexander Leaf
Protective effect of eicosapentaenoic acid on ouabain toxicity in neonatal rat cardiac myocytes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):7834-8.
1990: Alexander Leaf
Cardiovascular effects of fish oils. Beyond the platelet.
Circulation 1990;82(2):624-8.
1989: Alexander Leaf
Potential health effects of global climatic and environmental changes.
The New England journal of medicine 1989;321(23):1577-83.
1989: Thomas Force; C D Malis; J Luis Guerrero; G S Varadarajan; Joseph V Bonventre; P C Weber; Alexander Leaf
n-3 fatty acids increase postischemic blood flow but do not reduce myocardial necrosis.
The American journal of physiology 1989;257(4 Pt 2):H1204-10.
1989: Alexander Leaf
Cost effectiveness as a criterion for Medicare coverage.
The New England journal of medicine 1989;321(13):898-900.
1989: Alexander Leaf
Management of hypercholesterolemia. Are preventive interventions advisable?
The New England journal of medicine 1989;321(10):680-4.
1988: Alexander Leaf; P C Weber
Cardiovascular effects of n-3 fatty acids.
The New England journal of medicine 1988;318(9):549-57.
1986: J Y Cheung; J V Bonventre; C D Malis; Alexander Leaf
Calcium and ischemic injury.
The New England journal of medicine 1986;314(26):1670-6.
1983: C D Malis; J Y Cheung; Alexander Leaf; Joseph V Bonventre
Effects of verapamil in models of ischemic acute renal failure in the rat.
The American journal of physiology 1983;245(6):F735-42.