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John Lear

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TOP 3
Venura Samarasinghe; Vishal Madan; John T Lear
Focus on Basal cell carcinoma.
Sudarshan Ramachandran; Ratna Rajaratnam; Andrew G Smith; John T Lear; Richard C Strange
Patients with both basal and squamous cell carcinomas are at a lower risk of further basal cell carcinomas than patients with only a basal cell carcinoma.
Ursula Winters; Sai Daayana; John T Lear; Anne E Tomlinson; Eyad Elkord; Peter L Stern; Henry C Kitchener
Clinical and immunologic results of a phase II trial of sequential imiquimod and photodynamic therapy for vulval intraepithelial neoplasia.

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All Publications

2011: Venura Samarasinghe; Vishal Madan; John T Lear
Focus on Basal cell carcinoma.
Journal of skin cancer 2011;2011():328615.
2009: Sudarshan Ramachandran; Ratna Rajaratnam; Andrew G Smith; John T Lear; Richard C Strange
Patients with both basal and squamous cell carcinomas are at a lower risk of further basal cell carcinomas than patients with only a basal cell carcinoma.
Journal of the American Academy of Dermatology 2009;61(2):247-51.
2008: Ursula Winters; Sai Daayana; John T Lear; Anne E Tomlinson; Eyad Elkord; Peter L Stern; Henry C Kitchener
Clinical and immunologic results of a phase II trial of sequential imiquimod and photodynamic therapy for vulval intraepithelial neoplasia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5292-9.
2007: Vishal Madan; John T Lear
Minocycline-induced pigmentation of pre-existing capillaritis.
The British journal of dermatology 2007;156(3):590-1.
2006: Vishal Madan; Juliette A Loncaster; Donald Allan; John T Lear; Linda Sheridan; Catherine Leach; Ernest Allan
Nodular basal cell carcinoma in Gorlin's syndrome treated with systemic photodynamic therapy and interstitial optical fiber diffuser laser.
Journal of the American Academy of Dermatology 2006;55(5 Suppl):S86-9.
2006: S Y Chan; Vishal Madan; John T Lear; M Helbert
Highly active antiretroviral therapy-induced regression of basal cell carcinomas in a patient with acquired immunodeficiency and Gorlin syndrome.
The British journal of dermatology 2006;155(5):1079-80.
2006: V Madan; J Williams; John T Lear
Dermatological manifestations of Down's syndrome.
Clinical and experimental dermatology 2006;31(5):623-9.
2006: Paul Hoban; John T Lear; Richard C Strange
Basal cell carcinoma: genetic homogeneity in a tumour type displaying phenotypic diversity.
European journal of human genetics : EJHG 2006;14(9):977-8.
2006: Vishal Madan; Paul Hoban; R C Strange; Anthony A Fryer; John T Lear
Prognostic factors for a subsequent basal cell carcinoma: implications for follow-up.
The British journal of dermatology 2006;155(1):217-8.
2006: Vishal Madan; Paul Hoban; R C Strange; Anthony A Fryer; John T Lear
Genetics and risk factors for basal cell carcinoma.
The British journal of dermatology 2006;154 Suppl 1():5-7.
2005: Tracy J Lovatt; Julie Alldersea; John T Lear; Paul Hoban; Sudarshan Ramachandran; Anthony A Fryer; Andrew G Smith; Richard C Strange
Polymorphism in the nuclear excision repair gene ERCC2/XPD: association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma.
Human mutation 2005;25(4):353-9.
2005: Tracy J Lovatt; John T Lear; Jean Bastrilles; Christina Wong; Christopher E M Griffiths; Venura Samarasinghe; Jamie Roebuck; Sudarshan Ramachandran; Andrew G Smith; Peter W Jones; Anthony A Fryer; Richard C Strange
Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors.
Journal of the American Academy of Dermatology 2005;52(3 Pt 1):468-73.
2005: John T Lear; Paul Hoban; R C Strange; Anthony A Fryer
Basal cell carcinoma: from host response and polymorphic variants to tumour suppressor genes.
Clinical and experimental dermatology 2005;30(1):49-55.
2004: Tracy J Lovatt; John T Lear; Jean Bastrilles; Christina Wong; Christopher E M Griffiths; Sudarshan Ramachandran; Andrew G Smith; Asad Salim; Anthony A Fryer; Peter W Jones; Richard C Strange
Associations between UVR exposure and basal cell carcinoma site and histology.
Cancer letters 2004;216(2):191-7.
2004: Richard C Strange; N El-Genidy; Sudarshan Ramachandran; Tracy J Lovatt; Anthony A Fryer; Andrew G Smith; John T Lear; Christina Wong; Peter W Jones; Fumiyo Ichii-Jones; Paul Hoban
Susceptibility to basal cell carcinoma: associations with PTCH polymorphisms.
Annals of human genetics 2004;68(Pt 6):536-45.
2004: Richard C Strange; Noha El-Genidy; Sudarshan Ramachandran; Tracy J Lovatt; Anthony A Fryer; Andrew G Smith; John T Lear; Fumiyo Ichii-Jones; Peter W Jones; Paul Hoban
PTCH polymorphism is associated with the rate of increase in basal cell carcinoma numbers during follow-up: preliminary data on the influence of an exon 12-exon 23 haplotype.
Environmental and molecular mutagenesis 2004;44(5):469-76.
2003: Sudarshan Ramachandran; Anthony A Fryer; Tracy J Lovatt; Andrew G Smith; John T Lear; Peter W Jones; Richard C Strange
Combined effects of gender, skin type and polymorphic genes on clinical phenotype: use of rate of increase in numbers of basal cell carcinomas as a model system.
Cancer letters 2003;189(2):175-81.
2002: Majid Shahbazi; Vera Pravica; Najma Nasreen; Hana Fakhoury; Anthony A Fryer; Richard C Strange; Peter E Hutchinson; Joy E Osborne; John T Lear; Andrew G Smith; Ian Hutchinson
Association between functional polymorphism in EGF gene and malignant melanoma.
Lancet 2002;359(9304):397-401.
2001: S Ramachandran; Anthony A Fryer; A G Smith; John T Lear; B Bowers; A J Hartland; J R Whiteside; P W Jones; R C Strange
Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype.
Pharmacogenetics 2001;11(3):247-54.
2000: S Ramachandran; Anthony A Fryer; A G Smith; John T Lear; B Bowers; Christopher E M Griffiths; P W Jones; Richard C Strange
Basal cell carcinoma.
Cancer 2000;89(5):1012-8.
2000: Sudarshan Ramachandran; Paul Hoban; Fumiyo Ichii-Jones; L Pleasants; Francis Ali-Osman; John T Lear; Andrew G Smith; B Bowers; Peter W Jones; Anthony A Fryer; Richard C Strange
Glutathione S-transferase GSTP1 and cyclin D1 genotypes: association with numbers of basal cell carcinomas in a patient subgroup at high-risk of multiple tumours.
Pharmacogenetics 2000;10(6):545-56.
2000: Ali H Hajeer; John T Lear; W E R Ollier; Manuel Naves; Jane Worthington; D A Bell; A G Smith; W P Bowers; P W Jones; R C Strange; Anthony A Fryer
Preliminary evidence of an association of tumour necrosis factor microsatellites with increased risk of multiple basal cell carcinomas.
The British journal of dermatology 2000;142(3):441-5.
2000: Peter E Hutchinson; Joy E Osborne; John T Lear; A G Smith; P W Bowers; P N Morris; P W Jones; C York; R C Strange; Anthony A Fryer
Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):498-504.
1999: A Clairmont; Helmut Sies; S Ramachandran; John T Lear; A G Smith; B Bowers; P W Jones; Anthony A Fryer; R C Strange
Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci.
Carcinogenesis 1999;20(7):1235-40.
1999: Richard C Strange; T Ellison; Fumiyo Ichii-Jones; J Bath; Paul Hoban; John T Lear; Andrew G Smith; Peter E Hutchinson; J Osborne; B Bowers; Peter W Jones; Anthony A Fryer
Cytochrome P450 CYP2D6 genotypes: association with hair colour, Breslow thickness and melanocyte stimulating hormone receptor alleles in patients with malignant melanoma.
Pharmacogenetics 1999;9(3):269-76.
1999: Sudarshan Ramachandran; John T Lear; H Ramsay; Andrew G Smith; B Bowers; Peter E Hutchinson; Peter W Jones; Anthony A Fryer; Richard C Strange
Presentation with multiple cutaneous basal cell carcinomas: association of glutathione S-transferase and cytochrome P450 genotypes with clinical phenotype.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(1):61-7.
1998: Fumiyo Ichii-Jones; John T Lear; A H Heagerty; Andrew G Smith; Peter E Hutchinson; J Osborne; B Bowers; Peter W Jones; E Davies; W E Ollier; W Thomson; L Yengi; J Bath; Anthony A Fryer; Richard C Strange
Susceptibility to melanoma: influence of skin type and polymorphism in the melanocyte stimulating hormone receptor gene.
The Journal of investigative dermatology 1998;111(2):218-21.
1998: John T Lear; C Graham; S Pavord; V Mitchell; Peter E Hutchinson
Cutaneous vascular infarcts secondary to spontaneous platelet aggregation.
The British journal of dermatology 1998;138(6):1061-3.
1998: John T Lear; BB Tan; Andrew G Smith; Peter W Jones; A H Heagerty; Richard C Strange; Anthony A Fryer
A comparison of risk factors for malignant melanoma, squamous cell carcinoma and basal cell carcinoma in the UK.
International journal of clinical practice 1998;52(3):145-9.
1997: John T Lear; Andrew G Smith; A H Heagerty; B Bowers; Peter W Jones; J Gilford; Julie Alldersea; Richard C Strange; Anthony A Fryer
Truncal site and detoxifying enzyme polymorphisms significantly reduce time to presentation of further primary cutaneous basal cell carcinoma.
Carcinogenesis 1997;18(8):1499-503.
1997: John T Lear; BB Tan; Andrew G Smith; W Bowers; Peter W Jones; A H Heagerty; Richard C Strange; Anthony A Fryer
Risk factors for basal cell carcinoma in the UK: case-control study in 806 patients.
Journal of the Royal Society of Medicine 1997;90(7):371-4.
1997: BB Tan; A L Noble; M E Roberts; John T Lear; JS English
Allergic contact dermatitis from oleyl alcohol in lipstick cross-reacting with ricinoleic acid in castor oil and lanolin.
Contact dermatitis 1997;37(1):41-2.
1997: BB Tan; John T Lear; JS English
Latex contact urticaria presenting as facial swelling in a motor mechanic.
Contact dermatitis 1997;36(4):229-30.
1997: John T Lear; Andrew G Smith; B Bowers; A H Heagearty; Peter W Jones; J Gilford; Julie Alldersea; Richard C Strange; Anthony A Fryer
Truncal tumor site is associated with high risk of multiple basal cell carcinoma and is influenced by glutathione S-transferase, GSTT1, and cytochrome P450, CYP1A1 genotypes, and their interaction.
The Journal of investigative dermatology 1997;108(4):519-22.
1997: BB Tan; John T Lear; JS English
Metastasis from carcinoma of breast masquerading as chilblains.
Journal of the Royal Society of Medicine 1997;90(3):162.
1997: BB Tan; John T Lear; D J Gawkrodger; JS English
Azathioprine in dermatology: a survey of current practice in the U.K.
The British journal of dermatology 1997;136(3):351-5.
1997: BB Tan; John T Lear; Andrew G Smith
Acne fulminans and erythema nodosum during isotretinoin therapy responding to dapsone.
Clinical and experimental dermatology 1997;22(1):26-7.
1997: BB Tan; John T Lear; J Watts; P Jones; JS English
Perioperative collapse: prevalence of latex allergy in patients sensitive to anaesthetic agents.
Contact dermatitis 1997;36(1):47-50.