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P Lecine

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Concepts & Ideas

Cell Lineage

Physiology

Disorders

Thrombocytopenia

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Publications

TOP 3
H D Schwer; P Lecine; Sanjay Tiwari; Joseph E Italiano; John H Hartwig; Ramesh A Shivdasani
A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets.
P Lecine; Joseph E Italiano; Sang-We Kim; Jean-Luc Villeval; Ramesh A Shivdasani
Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.
Joseph E Italiano; P Lecine; Ramesh A Shivdasani; John H Hartwig
Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes.

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All Publications

2001: H D Schwer; P Lecine; Sanjay Tiwari; Joseph E Italiano; John H Hartwig; Ramesh A Shivdasani
A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets.
Current biology : CB 2001;11(8):579-86.
2000: P Lecine; Joseph E Italiano; Sang-We Kim; Jean-Luc Villeval; Ramesh A Shivdasani
Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.
Blood 2000;96(4):1366-73.
1999: Joseph E Italiano; P Lecine; Ramesh A Shivdasani; John H Hartwig
Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes.
The Journal of cell biology 1999;147(6):1299-312.
1999: J Levin; J P Peng; G R Baker; Jean-Luc Villeval; P Lecine; SA Burstein; Ramesh A Shivdasani
Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2.
Blood 1999;94(9):3037-47.
1998: P Lecine; Jean-Luc Villeval; P Vyas; B Swencki; Y Xu; Ramesh A Shivdasani
Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes.
Blood 1998;92(5):1608-16.
1998: P Lecine; V Blank; Ramesh A Shivdasani
Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes.
The Journal of biological chemistry 1998;273(13):7572-8.
1998: P Lecine; Ramesh A Shivdasani
Cellular and molecular biology of megakaryocyte differentiation in the absence of lineage-restricted transcription factors.
Stem cells (Dayton, Ohio) 1998;16 Suppl 2():91-5.

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