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Claude Leclerc
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39
Lo-Man, Richard
28
Hofnung, Maurice
21
Fayolle, Catherine
21
Martineau, P
20
Dériaud, Edith
18
Ladant, Daniel
17
Deriaud, Edith
17
Sebo, Peter
16
Majlessi, Laleh
15
Charbit, Alain
13
Sedlik, Christine
11
Dadaglio, Gilles
11
Gicquel, Brigitte
10
Bay, Sylvie
10
Brodin, Priscille
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All Publications
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2009: Bay S; Fort S; Birikaki L; Ganneau C; Samain E; Coïc Y-M; Bonhomme F; Dériaud E; Leclerc C; Lo-Man R
Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide.
ChemMedChem 2009;4(4):582-7.
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2009: Badell Edgar; Nicolle Fabienne; Clark Simon; Majlessi Laleh; Boudou Frédéric; Martino Angelo; Castello-Branco Luiz; Leclerc Claude; Lewis David J M; Marsh Philip D; Gicquel Brigitte; Winter Nathalie
Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-gamma producing T-cells.
Vaccine 2009;27(1):28-37.
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2008: Mouriès Juliette; Moron Gabriel; Schlecht Géraldine; Escriou Nicolas; Dadaglio Gilles; Leclerc Claude
Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation.
Blood 2008;112(9):3713-22.
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2008: Leclerc Claude; Brose Claudia; Nouzé Clémence; Leonard Fransisca; Majlessi Laleh; Becker Sybille; von Briesen Hagen; Lo-Man Richard
Immobilized cytokines as biomaterials for manufacturing immune cell based vaccines.
Journal of biomedical materials research. Part A 2008;86(4):1033-40.
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2008: Majlessi Laleh; Lo-Man Richard; Leclerc Claude
Regulatory B and T cells in infections.
Microbes and infection / Institut Pasteur 2008;10(9):1030-5.
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2008: Doré Grégory; Leclerc Claude; Lazarini Françoise
Treatment by CpG or Flt3-ligand does not affect mouse susceptibility to BSE prions.
Journal of neuroimmunology 2008;197(1):74-80.
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2008: Frigui Wafa; Bottai Daria; Majlessi Laleh; Monot Marc; Josselin Emmanuelle; Brodin Priscille; Garnier Thierry; Gicquel Brigitte; Martin Carlos; Leclerc Claude; Cole Stewart T; Brosch Roland
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.
PLoS pathogens 2008;4(2):e33.
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2008: Jaron Barbara; Maranghi Eddie; Leclerc Claude; Majlessi Laleh
Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis.
PloS one 2008;3(7):e2833.
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2007: Berraondo Pedro; Nouzé Clémence; Préville Xavier; Ladant Daniel; Leclerc Claude
Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system.
Cancer research 2007;67(18):8847-55.
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2007: Majlessi Laleh; Combaluzier Benoit; Albrecht Imke; Garcia Jessica E; Nouze Clémence; Pieters Jean; Leclerc Claude
Inhibition of phagosome maturation by mycobacteria does not interfere with presentation of mycobacterial antigens by MHC molecules.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1825-33.
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2007: Connell Tom G; Shey Muki S; Seldon Ronnett; Rangaka Molebogeng X; van Cutsem Gilles; Simsova Marcela; Marcekova Zuzana; Sebo Peter; Curtis Nigel; Diwakar Lavanya; Meintjes Graeme A; Leclerc Claude; Wilkinson Robert J; Wilkinson Katalin A
Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector.
Clinical and vaccine immunology : CVI 2007;14(7):847-54.
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2007: Hervas-Stubbs Sandra; Olivier Aurélie; Boisgerault Florence; Thieblemont Nathalie; Leclerc Claude
TLR3 ligand stimulates fully functional memory CD8+ T cells in the absence of CD4+ T-cell help.
Blood 2007;109(12):5318-26.
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2007: Zhang Xiaoming; Deriaud Edith; Jiao Xinan; Braun Deborah; Leclerc Claude; Lo-Man Richard
Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells.
The Journal of experimental medicine 2007;204(5):1107-18.
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2007: Leclerc Claude
[New technologies for vaccine development]
Médecine sciences : M/S 2007;23(4):386-90.
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2007: Hervas-Stubbs Sandra; Rueda Paloma; Lopez Lissette; Leclerc Claude
Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2361-9.
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2006: Freire Teresa; Bay Sylvie; Vichier-Guerre Sophie; Lo-Man Richard; Leclerc Claude
Carbohydrate antigens: synthesis aspects and immunological applications in cancer.
Mini reviews in medicinal chemistry 2006;6(12):1357-73.
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2006: Bertrand Julien Y; Desanti Guillaume E; Lo-Man Richard; Leclerc Claude; Cumano Ana; Golub Rachel
Fetal spleen stroma drives macrophage commitment.
Development (Cambridge, England) 2006;133(18):3619-28.
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2006: Hervas-Stubbs Sandra; Majlessi Laleh; Simsova Marcela; Morova Jana; Rojas Marie-Jesus; Nouzé Clémence; Brodin Priscille; Sebo Peter; Leclerc Claude
High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection.
Infection and immunity 2006;74(6):3396-407.
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2006: Rybner-Barnier Catherine; Jacquemot Catherine; Cuche Céline; Doré Grégory; Majlessi Laleh; Gabellec Marie-Madeleine; Moris Arnaud; Schwartz Olivier; Di Santo James; Cumano Ana; Leclerc Claude; Lazarini Françoise
Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells.
Journal of virology 2006;80(10):4656-63.
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2006: Freire Teresa; Lo-Man Richard; Piller Friedrich; Piller Véronique; Leclerc Claude; Bay Sylvie
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.
Glycobiology 2006;16(5):390-401.
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2006: Majlessi Laleh; Simsova Marcela; Jarvis Zdenka; Brodin Priscille; Rojas Marie-Jésus; Bauche Cécile; Nouzé Clémence; Ladant Daniel; Cole Stewart T; Sebo Peter; Leclerc Claude
An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis.
Infection and immunity 2006;74(4):2128-37.
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2006: Mascarell Laurent; Bauche Cecile; Fayolle Catherine; Diop Ousmane M; Dupuy Monique; Nougarede Nolwenn; Perraut Ronald; Ladant Daniel; Leclerc Claude
Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates.
Vaccine 2006;24(17):3490-9.
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2006: Schlecht Géraldine; Mouriès Juliette; Poitrasson-Rivière Maud; Leclerc Claude; Dadaglio Gilles
Purification of splenic dendritic cells induces maturation and capacity to stimulate Th1 response in vivo.
International immunology 2006;18(3):445-52.
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2006: Brodin Priscille; Majlessi Laleh; Marsollier Laurent; de Jonge Marien I; Bottai Daria; Demangel Caroline; Hinds Jason; Neyrolles Olivier; Butcher Philip D; Leclerc Claude; Cole Stewart T; Brosch Roland
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence.
Infection and immunity 2006;74(1):88-98.
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2005: Brodin Priscille; de Jonge Marien I; Majlessi Laleh; Leclerc Claude; Nilges Michael; Cole Stewart T; Brosch Roland
Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity.
The Journal of biological chemistry 2005;280(40):33953-9.
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2005: Grigalevicius Saulius; Chierici Sabine; Renaudet Olivier; Lo-Man Richard; Dériaud Edith; Leclerc Claude; Dumy Pascal
Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines.
Bioconjugate chemistry 2005;16(5):1149-59.
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2005: Masin Jiri; Basler Marek; Knapp Oliver; El-Azami-El-Idrissi Mohammed; Maier Elke; Konopasek Ivo; Benz Roland; Leclerc Claude; Sebo Peter
Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells.
Biochemistry 2005;44(38):12759-66.
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2005: Mascarell Laurent; Fayolle Catherine; Bauche Cécile; Ladant Daniel; Leclerc Claude
Induction of neutralizing antibodies and Th1-polarized and CD4-independent CD8+ T-cell responses following delivery of human immunodeficiency virus type 1 Tat protein by recombinant adenylate cyclase of Bordetella pertussis.
Journal of virology 2005;79(15):9872-84.
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2005: Wilkinson Katalin A; Simsova Marcela; Schölvinck Elisabeth; Sebo Peter; Leclerc Claude; Vordermeier H Martin; Dickson Stuart J; Brown Jillian R; Davidson Robert N; Pasvol Geoffrey; Levin Michael; Wilkinson Robert J
Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids.
Infection and immunity 2005;73(5):2991-8.
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2005: Sun Cheng-Ming; Deriaud Edith; Leclerc Claude; Lo-Man Richard
Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs.
Immunity 2005;22(4):467-77.
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2005: Majlessi Laleh; Brodin Priscille; Brosch Roland; Rojas Marie-Jésus; Khun Huot; Huerre Michel; Cole Stewart T; Leclerc Claude
Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3570-9.
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2005: Boisgérault Florence; Rueda Paloma; Sun Cheng Ming; Hervas-Stubbs Sandra; Rojas Marie; Leclerc Claude
Cross-priming of T cell responses by synthetic microspheres carrying a CD8+ T cell epitope requires an adjuvant signal.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3432-9.
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2005: Préville Xavier; Ladant Daniel; Timmerman Benedikt; Leclerc Claude
Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein.
Cancer research 2005;65(2):641-9.
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2004: Fayolle Catherine; Bauche Cécile; Ladant Daniel; Leclerc Claude
Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo.
Vaccine 2004;23(5):604-14.
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2004: Schlecht Géraldine; Loucka Jirina; Najar Hossain; Sebo Peter; Leclerc Claude
Antigen targeting to CD11b allows efficient presentation of CD4+ and CD8+ T cell epitopes and in vivo Th1-polarized T cell priming.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6089-97.
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2004: Vordermeier H Martin; Simsova Marcela; Wilkinson Katalin A; Wilkinson Robert J; Hewinson R Glyn; Sebo Peter; Leclerc Claude
Recognition of mycobacterial antigens delivered by genetically detoxified Bordetella pertussis adenylate cyclase by T cells from cattle with bovine tuberculosis.
Infection and immunity 2004;72(11):6255-61.
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2004: Schlecht Géraldine; Garcia Sylvie; Escriou Nicolas; Freitas Antonio A; Leclerc Claude; Dadaglio Gilles
Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation.
Blood 2004;104(6):1808-15.
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2004: Regner Matthias; Martinez Xavier; Belnoue Elodie; Sun Cheng-Ming; Boisgerault Florence; Lambert Paul-Henri; Leclerc Claude; Siegrist Claire-Anne
Partial activation of neonatal CD11c+ dendritic cells and induction of adult-like CD8+ cytotoxic T cell responses by synthetic microspheres.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2669-74.
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2004: Lo-Man Richard; Vichier-Guerre Sophie; Perraut Ronald; Dériaud Edith; Huteau Valérie; BenMohamed Lbachir; Diop Ousmane M; Livingston Philip O; Bay Sylvie; Leclerc Claude
A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates.
Cancer research 2004;64(14):4987-94.
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2004: Brodin Priscille; Majlessi Laleh; Brosch Roland; Smith Debbie; Bancroft Gregory; Clark Simon; Williams Ann; Leclerc Claude; Cole Stewart T
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens.
The Journal of infectious diseases 2004;190(1):115-22.
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2004: Vichier-Guerre Sophie; Lo-Man Richard; Huteau Valérie; Dériaud Edith; Leclerc Claude; Bay Sylvie
Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen.
Bioorganic & medicinal chemistry letters 2004;14(13):3567-70.
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2004: Simsova Marcela; Sebo Peter; Leclerc Claude
The adenylate cyclase toxin from Bordetella pertussis--a novel promising vehicle for antigen delivery to dendritic cells.
International journal of medical microbiology : IJMM 2004;293(7-8):571-6.
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2004: Demangel Caroline; Brodin Priscille; Cockle Paul J; Brosch Roland; Majlessi Laleh; Leclerc Claude; Cole Stewart T
Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.
Infection and immunity 2004;72(4):2170-6.
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2004: Rueda P; Morón G; Sarraseca J; Leclerc C; Casal J I
Influence of flanking sequences on presentation efficiency of a CD8+ cytotoxic T-cell epitope delivered by parvovirus-like particles.
The Journal of general virology 2004;85(Pt 3):563-72.
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2004: Morón Gabriel; Dadaglio Gilles; Leclerc Claude
New tools for antigen delivery to the MHC class I pathway.
Trends in immunology 2004;25(2):92-7.
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2003: Dadaglio Gilles; Morel Sandra; Bauche Cécile; Moukrim Zhora; Lemonnier François A; Van Den Eynde Benoît J; Ladant Daniel; Leclerc Claude
Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes.
International immunology 2003;15(12):1423-30.
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2003: Majlessi Laleh; Rojas Marie-Jésus; Brodin Priscille; Leclerc Claude
CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family.
Infection and immunity 2003;71(12):7173-7.
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2003: El-Azami-El-Idrissi Mohammed; Bauche Cécile; Loucka Jirina; Osicka Radim; Sebo Peter; Ladant Daniel; Leclerc Claude
Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain.
The Journal of biological chemistry 2003;278(40):38514-21.
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2003: Leclerc Claude
New approaches in vaccine development.
Comparative immunology, microbiology and infectious diseases 2003;26(5-6):329-41.
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2003: Morón Víctor Gabriel; Rueda Paloma; Sedlik Christine; Leclerc Claude
In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2242-50.
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2003: Vichier-Guerre S; Lo-Man R; BenMohamed L; Dériaud E; Kovats S; Leclerc C; Bay S
Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use.
The journal of peptide research : official journal of the American Peptide Society 2003;62(3):117-24.
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2003: Sun Cheng-Ming; Fiette Laurence; Tanguy Myriam; Leclerc Claude; Lo-Man Richard
Ontogeny and innate properties of neonatal dendritic cells.
Blood 2003;102(2):585-91.
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2003: Pym Alexander S; Brodin Priscille; Majlessi Laleh; Brosch Roland; Demangel Caroline; Williams Ann; Griffiths Karen E; Marchal Gilles; Leclerc Claude; Cole Stewart T
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.
Nature medicine 2003;9(5):533-9.
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2003: Jiao Xinan; Lo-Man Richard; Winter Nathalie; Dériaud Edith; Gicquel Brigitte; Leclerc Claude
The shift of Th1 to Th2 immunodominance associated with the chronicity of Mycobacterium bovis bacille Calmette-Guérin infection does not affect the memory response.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1392-8.
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2003: Martinez Xavier; Regner Matthias; Kovarik Jiri; Zarei Shohreh; Hauser Conrad; Lambert Paul-Henri; Leclerc Claude; Siegrist Claire-Anne
CD4-independent protective cytotoxic T cells induced in early life by a non-replicative delivery system based on virus-like particles.
Virology 2003;305(2):428-35.
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2002: El Azami El Idrissi M; Ladant D; Leclerc C
The adenylate cyclase of Bordetella pertussis: a vector to target antigen presenting cells.
Toxicon : official journal of the International Society on Toxinology 2002;40(12):1661-5.
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2002: Guermonprez Pierre; Fayolle Catherine; Rojas Marie-Jésus; Rescigno Maria; Ladant Daniel; Leclerc Claude
In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells.
European journal of immunology 2002;32(11):3071-81.
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2002: Boisgérault Florence; Morón Gabriel; Leclerc Claude
Virus-like particles: a new family of delivery systems.
Expert review of vaccines 2002;1(1):101-9.
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2002: Ghosh Mrinal K; Li Cui-Ling; Fayolle Catherine; Dadaglio Gilles; Murphy Aileen; Lemonnier François A; Roy Polly; Leclerc Claude
Induction of HLA-A2-restricted CTL responses by a tubular structure carrying human melanoma epitopes.
Vaccine 2002;20(19-20):2463-73.
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2002: Morón Gabriel; Rueda Paloma; Casal Ignacio; Leclerc Claude
CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules.
The Journal of experimental medicine 2002;195(10):1233-45.
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2002: Dadaglio Gilles; Sun Cheng-Ming; Lo-Man Richard; Siegrist Claire Anne; Leclerc Claude
Efficient in vivo priming of specific cytotoxic T cell responses by neonatal dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2219-24.
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2002: Jiao Xinan; Lo-Man Richard; Guermonprez Pierre; Fiette Laurence; Dériaud Edith; Burgaud Sophie; Gicquel Brigitte; Winter Nathalie; Leclerc Claude
Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1294-301.
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2002: Loucká Jiina; Schlecht Géraldine; Vodolánová Jana; Leclerc Claude; Sebo Peter
Delivery of a MalE CD4(+)-T-cell epitope into the major histocompatibility complex class II antigen presentation pathway by Bordetella pertussis adenylate cyclase.
Infection and immunity 2002;70(2):1002-5.
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2002: Ghosh Mrinal K; Dériaud Edith; Saron Marie Françoise; Lo-Man Richard; Henry Thomas; Jiao Xinan; Roy Polly; Leclerc Claude
Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences.
Vaccine 2002;20(9-10):1369-77.
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2001: Schlecht G; Leclerc C; Dadaglio G
Induction of CTL and nonpolarized Th cell responses by CD8alpha(+) and CD8alpha(-) dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4215-21.
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2001: Fayolle C; Osickova A; Osicka R; Henry T; Rojas M J; Saron M F; Sebo P; Leclerc C
Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity.
Journal of virology 2001;75(16):7330-8.
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2001: Guermonprez P; Khelef N; Blouin E; Rieu P; Ricciardi-Castagnoli P; Guiso N; Ladant D; Leclerc C
The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18).
The Journal of experimental medicine 2001;193(9):1035-44.
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2001: Lo-Man R; Vichier-Guerre S; Bay S; Dériaud E; Cantacuzène D; Leclerc C
Anti-tumor immunity provided by a synthetic multiple antigenic glycopeptide displaying a tri-Tn glycotope.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2849-54.
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2000: Coëffier E; Clément J M; Cussac V; Khodaei-Boorane N; Jehanno M; Rojas M; Dridi A; Latour M; El Habib R; Barré-Sinoussi F; Hofnung M; Leclerc C
Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein.
Vaccine 2000;19(7-8):684-93.
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2000: Dadaglio G; Moukrim Z; Lo-Man R; Sheshko V; Sebo P; Leclerc C
Induction of a polarized Th1 response by insertion of multiple copies of a viral T-cell epitope into adenylate cyclase of Bordetella pertussis.
Infection and immunity 2000;68(7):3867-72.
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2000: Sedlik C; Dadaglio G; Saron M F; Deriaud E; Rojas M; Casal S I; Leclerc C
In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity.
Journal of virology 2000;74(13):5769-75.
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2000: Lo-Man R; Langeveld J P; Dériaud E; Jehanno M; Rojas M; Clément J M; Meloen R H; Hofnung M; Leclerc C
Extending the CD4(+) T-cell epitope specificity of the Th1 immune response to an antigen using a Salmonella enterica serovar typhimurium delivery vehicle.
Infection and immunity 2000;68(6):3079-89.
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2000: Himmelrich H; Lo-Man R; Winter N; Guermonprez P; Sedlik C; Rojas M; Monnaie D; Gheorghiu M; Lagranderie M; Hofnung M; Gicquel B; Clément J M; Leclerc C
Immune responses induced by recombinant BCG strains according to level of production of a foreign antigen: malE.
Vaccine 2000;18(24):2636-47.
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2000: Vichier-Guerre S; Lo-Man R; Bay S; Deriaud E; Nakada H; Leclerc C; Cantacuzène D
Short synthetic glycopeptides successfully induce antibody responses to carcinoma-associated Tn antigen.
The journal of peptide research : official journal of the American Peptide Society 2000;55(2):173-80.
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2000: Osicka R; Osicková A; Basar T; Guermonprez P; Rojas M; Leclerc C; Sebo P
Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites.
Infection and immunity 2000;68(1):247-56.
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2000: Guermonprez P; Fayolle C; Karimova G; Ullmann A; Leclerc C; Ladant D
Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells.
Methods in enzymology 2000;326():527-42.
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1999: Guermonprez P; Lo-Man R; Sedlik C; Rojas M J; Poljak R J; Leclerc C
mAb against hen egg-white lysozyme regulate its presentation to CD4(+) T cells.
International immunology 1999;11(11):1863-72.
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1999: Sebo P; Moukrim Z; Kalhous M; Schaft N; Dadaglio G; Sheshko V; Fayolle C; Leclerc C
In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying multiple copies of a viral CD8(+) T-cell epitope.
FEMS immunology and medical microbiology 1999;26(2):167-73.
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1999: Rueda P; Hurtado A; del Barrio M; Martínez-Torrecuadrada J L; Kamstrup S; Leclerc C; Casal J I
Minor displacements in the insertion site provoke major differences in the induction of antibody responses by chimeric parvovirus-like particles.
Virology 1999;263(1):89-99.
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1999: Rueda P; Martínez-Torrecuadrada J L; Sarraseca J; Sedlik C; del Barrio M; Hurtado A; Leclerc C; Casal J I
Engineering parvovirus-like particles for the induction of B-cell, CD4(+) and CTL responses.
Vaccine 1999;18(3-4):325-32.
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1999: Fayolle C; Ladant D; Karimova G; Ullmann A; Leclerc C
Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T cell epitope.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4157-62.
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1999: Lo-Man R; Bay S; Vichier-Guerre S; Dériaud E; Cantacuzène D; Leclerc C
A fully synthetic immunogen carrying a carcinoma-associated carbohydrate for active specific immunotherapy.
Cancer research 1999;59(7):1520-4.
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1999: Sedlik C; Dridi A; Deriaud E; Saron M F; Rueda P; Sarraseca J; Casal J I; Leclerc C
Intranasal delivery of recombinant parvovirus-like particles elicits cytotoxic T-cell and neutralizing antibody responses.
Journal of virology 1999;73(4):2739-44.
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1999: Guermonprez P; Ladant D; Karimova G; Ullmann A; Leclerc C
Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):1910-6.
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1999: Wang J; Michel V; Leclerc C; Hofnung M; Charbit A
Immunogenicity of viral B-cell epitopes inserted into two surface loops of the Escherichia coli K12 LamB protein and expressed in an attenuated aroA strain of Salmonella typhimurium.
Vaccine 1999;17(1):1-12.
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1998: Guermonprez P; England P; Bedouelle H; Leclerc C
The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4542-8.
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1998: Karimova G; Fayolle C; Gmira S; Ullmann A; Leclerc C; Ladant D
Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12532-7.
-
1998: Sedlik C; Rojas M; Leclerc C
Activation of B cells by 1 microm particulate lysozyme or peptides: a Th-dependent pathway requiring CD40-CD40 ligand interaction.
International immunology 1998;10(8):1111-9.
-
1998: Coëffier E; Girard M; Barré-Sinoussi F; Meignier B; Muchmore E; Fultz P N; LeClerc C
Fine specificity of anti-V3 antibodies induced in chimpanzees by HIV candidate vaccines.
AIDS research and human retroviruses 1998;14(12):1023-34.
-
1998: Leclerc C; Ronco J
New approaches in vaccine development.
Immunology today 1998;19(7):300-2.
-
1998: Lo-Man R; Rueda P; Sedlik C; Deriaud E; Casal I; Leclerc C
A recombinant virus-like particle system derived from parvovirus as an efficient antigen carrier to elicit a polarized Th1 immune response without adjuvant.
European journal of immunology 1998;28(4):1401-7.
-
1998: Lo-Man R; Langeveld J P; Martineau P; Hofnung M; Meloen R H; Leclerc C
Immunodominance does not result from peptide competition for MHC class II presentation.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1759-66.
-
1997: Coëffier E; Excler J L; Kieny M P; Meignier B; Moste C; Tartaglia J; Pialoux G; Salmon-Céron D; Leclerc C
Restricted specificity of anti-V3 antibodies induced in humans by HIV candidate vaccines.
AIDS research and human retroviruses 1997;13(17):1471-85.
-
1997: Sirard J C; Fayolle C; de Chastellier C; Mock M; Leclerc C; Berche P
Intracytoplasmic delivery of listeriolysin O by a vaccinal strain of Bacillus anthracis induces CD8-mediated protection against Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4435-43.
-
1997: Leclerc C; Dériaud E; Rojas M; Whalen R G
The preferential induction of a Th1 immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA.
Cellular immunology 1997;179(2):97-106.
-
1997: Lagranderie M; Lo-Man R; Dériaud E; Gicquel B; Gheorghiu M; Leclerc C
Genetic control of antibody responses induced by recombinant Mycobacterium bovis BCG expressing a foreign antigen.
Infection and immunity 1997;65(8):3057-64.
-
1997: Sedlik C; Saron M; Sarraseca J; Casal I; Leclerc C
Recombinant parvovirus-like particles as an antigen carrier: a novel nonreplicative exogenous antigen to elicit protective antiviral cytotoxic T cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7503-8.
-
1997: Bay S; Lo-Man R; Osinaga E; Nakada H; Leclerc C; Cantacuzène D
Preparation of a multiple antigen glycopeptide (MAG) carrying the Tn antigen. A possible approach to a synthetic carbohydrate vaccine.
The journal of peptide research : official journal of the American Peptide Society 1997;49(6):620-5.
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1997: Leclerc C; Martineau P; Charlot B; Delpeyroux F; van der Werf S; Hofnung M
Control by Ig genes of the responsiveness to a neutralization viral B cell epitope.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3252-8.
-
1997: Saron M F; Fayolle C; Sebo P; Ladant D; Ullmann A; Leclerc C
Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3314-9.
-
1997: Charbit A; Newton S M; Klebba P E; Clément J M; Fayolle C; Lo-Man R; Leclerc C; Hofnung M
Expression and immune response to foreign epitopes in bacteria. Perspectives for live vaccine development.
Behring Institute Mitteilungen 1997;(98):135-42.
-
1997: Sedlik C; Dériaud E; Leclerc C
Lack of Th1 or Th2 polarization of CD4+ T cell response induced by particulate antigen targeted to phagocytic cells.
International immunology 1997;9(1):91-103.
-
1996: Martineau P; Leclerc C; Hofnung M
Modulating the immunological properties of a linear B-cell epitope by insertion into permissive sites of the MalE protein.
Molecular immunology 1996;33(17-18):1345-58.
-
1996: Lo-Man R; Martineau P; Dériaud E; Newton S M; Jehanno M; Clément J M; Fayolle C; Hofnung M; Leclerc C D
Control by H-2 genes of the Th1 response induced against a foreign antigen expressed by attenuated Salmonella typhimurium.
Infection and immunity 1996;64(11):4424-32.
-
1996: Lo-Man R; Martineau P; Hofnung M; Leclerc C
Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background.
Cellular immunology 1996;172(2):180-91.
-
1996: Fayolle C; Abdel-Motal U M; Berg L; Deriaud E; Jondal M; Leclerc C
Induction of cytotoxic T-cell response by optimal-length peptides does not require CD4+ T-cell help.
Immunology 1996;89(1):41-5.
-
1996: Lo-Man R; Martineau P; Manoury-Schwartz B; Hofnung M; Leclerc C
Overcoming the crypticity of a viral T cell determinant by insertion into a chimeric bacterial protein.
International immunology 1996;8(8):1245-55.
-
1996: Fayolle C; Sebo P; Ladant D; Ullmann A; Leclerc C
In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4697-706.
-
1996: Sedlik C; Perraut R; Bonnemains B; Leclerc C
Antigens linked to synthetic microspheres induce immune responses in primates in the absence of adjuvant.
Immunobiology 1996;195(1):105-18.
-
1996: Lagranderie M R; Balazuc A M; Deriaud E; Leclerc C D; Gheorghiu M
Comparison of immune responses of mice immunized with five different Mycobacterium bovis BCG vaccine strains.
Infection and immunity 1996;64(1):1-9.
-
1995: Whalen R G; Leclerc C; Dériaud E; Schirmbeck R; Reimann J; Davis H L
DNA-mediated immunization to the hepatitis B surface antigen. Activation and entrainment of the immune response.
Annals of the New York Academy of Sciences 1995;772():64-76.
-
1995: Sebo P; Fayolle C; d'Andria O; Ladant D; Leclerc C; Ullmann A
Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells.
Infection and immunity 1995;63(10):3851-7.
-
1995: Leclerc C; Sedlik C; Lo-Man R; Charlot B; Rojas M; Dériaud E
Stimulation of a memory B cell response does not require primed helper T cells.
European journal of immunology 1995;25(9):2533-8.
-
1995: Sedlik C; Sarraseca J; Rueda P; Leclerc C; Casal I
Immunogenicity of poliovirus B and T cell epitopes presented by hybrid porcine parvovirus particles.
The Journal of general virology 1995;76 ( Pt 9)():2361-8.
-
1995: Escriou N; Leclerc C; Gerbard S; Giraud M; van der Werf S
Cytotoxic T cell response to Mengo virus in mice: effector cell phenotype and target proteins.
The Journal of general virology 1995;76 ( Pt 8)():1999-2007.
-
1995: Winter N; Lagranderie M; Gangloff S; Leclerc C; Gheorghiu M; Gicquel B
Recombinant BCG strains expressing the SIVmac251nef gene induce proliferative and CTL responses against nef synthetic peptides in mice.
Vaccine 1995;13(5):471-8.
-
1995: Gengoux C; Leclerc C
In vivo induction of CD4+ T cell responses by antigens covalently linked to synthetic microspheres does not require adjuvant.
International immunology 1995;7(1):45-53.
-
1994: Castignolles N; Betbeder D; Ioualalen K; Merten O; Leclerc C; Samain D; Perrin P
Stabilization and enhancement of interleukin-2 in vitro bioactivity by new carriers: supramolecular biovectors.
Vaccine 1994;12(15):1413-8.
-
1994: Fayolle C; O'Callaghan D; Martineau P; Charbit A; Clément J M; Hofnung M; Leclerc C
Genetic control of antibody responses induced against an antigen delivered by recombinant attenuated Salmonella typhimurium.
Infection and immunity 1994;62(10):4310-9.
-
1994: Gheorghiu M; Lagranderie M R; Gicquel B M; Leclerc C D
Mycobacterium bovis BCG priming induces a strong potentiation of the antibody response induced by recombinant BCG expressing a foreign antigen.
Infection and immunity 1994;62(10):4287-95.
-
1994: Lo-Man R; Martineau P; Betton J M; Hofnung M; Leclerc C
Molecular context of a viral T cell determinant within a chimeric bacterial protein alters the diversity of its T cell recognition.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(12):5660-9.
-
1994: Leclerc C; Lo-Man R; Fayolle C; Charbit A; Clément J M; Martineau P; O'Callaghan D; Hofnung M
Molecular and cellular parameters controlling the immunogenicity of foreign B- or T-cell epitopes expressed by recombinant vectors.
Developments in biological standardization 1994;82():193-9.
-
1994: Leclerc C; Lo-Man R; Charbit A; Martineau P; Clément J M; Hofnung M
Immunogenicity of viral B- and T-cell epitopes expressed in recombinant bacterial proteins.
International reviews of immunology 1994;11(2):123-32.
-
1993: Leclerc C; Martineau P; Charbit A; Lo-Man R; Dériaud E; Hofnung M
Immunodominance of a recombinant T-cell epitope depends on its molecular environment.
Molecular immunology 1993;30(17):1561-72.
-
1993: Lo-Man R; Martineau P; Hofnung M; Leclerc C
Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope.
European journal of immunology 1993;23(11):2998-3002.
-
1993: Lagranderie M; Murray A; Gicquel B; Leclerc C; Gheorghiu M
Oral immunization with recombinant BCG induces cellular and humoral immune responses against the foreign antigen.
Vaccine 1993;11(13):1283-90.
-
1993: Charbit A; Martineau P; Ronco J; Leclerc C; Lo-Man R; Michel V; O'Callaghan D; Hofnung M
Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two Escherichia coli carrier proteins.
Vaccine 1993;11(12):1221-8.
-
1993: Galelli A; Charlot B; Dériaud E; Leclerc C
B cells do not present antigen covalently linked to microspheres.
Immunology 1993;79(1):69-76.
-
1993: Leclerc C; Dériaud E; Megret F; Briand J P; Van Regenmortel M H; Deubel V
Identification of helper T cell epitopes of dengue virus E-protein.
Molecular immunology 1993;30(7):613-25.
-
1993: O'Callaghan D; Martineau P; Fayolle C; Leclerc C; Guillet J G; Charbit A; Hofnung M
Immune responses to hybrid maltose-binding proteins.
Vaccine 1993;11(2):140-2.
-
1992: Murray A; Winter N; Lagranderie M; Hill D F; Rauzier J; Timm J; Leclerc C; Moriarty K M; Gheorghiu M; Gicquel B
Expression of Escherichia coli beta-galactosidase in Mycobacterium bovis BCG using an expression system isolated from Mycobacterium paratuberculosis which induced humoral and cellular immune responses.
Molecular microbiology 1992;6(22):3331-42.
-
1992: Martineau P; Guillet J G; Leclerc C; Hofnung M
Expression of heterologous peptides at two permissive sites of the MalE protein: antigenicity and immunogenicity of foreign B-cell and T-cell epitopes.
Gene 1992;118(1):151.
-
1992: Clément J M; Charbit A; Leclerc C; Martineau P; Muir S; O'Callaghan D; Popescu O; Szmelcman S; Hofnung M
Molecular and cellular targeting in the expression of foreign polypeptides in bacteria.
Antonie van Leeuwenhoek 1992;61(2):143-52.
-
1992: Schutze M P; Langlade-Demoyen P; Leclerc C
Alloantigen-specific regulation of cytotoxic T cell responses is mediated through the induction of clonal anergy of CD8+ T cells.
European journal of immunology 1992;22(2):387-92.
-
1991: Winter N; Lagranderie M; Rauzier J; Timm J; Leclerc C; Guy B; Kieny M P; Gheorghiu M; Gicquel B
Expression of heterologous genes in Mycobacterium bovis BCG: induction of a cellular response against HIV-1 Nef protein.
Gene 1991;109(1):47-54.
-
1991: Fayolle C; Deriaud E; Leclerc C
In vivo induction of cytotoxic T cell response by a free synthetic peptide requires CD4+ T cell help.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4069-73.
-
1991: Leclerc C; Charbit A; Martineau P; Deriaud E; Hofnung M
The cellular location of a foreign B cell epitope expressed by recombinant bacteria determines its T cell-independent or T cell-dependent characteristics.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(10):3545-52.
-
1991: Perrin P; Joffret M L; Zanetti C; Bourhy H; Gontier C; Fritzell C; Leclerc C; Sureau P
Rabies-specific production of interleukin-2 by peripheral blood lymphocytes from human rabies vaccinees.
Vaccine 1991;9(8):549-58.
-
1991: Rueff-Juy D; Liberman I; Drapier A M; Guillon J C; Leclerc C; Cazenave P A
Cellular basis of the resistance of newborn mice to the pathogenic effects of anti-CD3 treatment.
International immunology 1991;3(7):683-90.
-
1991: Joffret M L; Zanetti C; Morgeaux S; Leclerc C; Sureau P; Perrin P
Appraisal of rabies vaccine potency by determination of in vitro, specific interleukin-2 production.
Biologicals : journal of the International Association of Biological Standardization 1991;19(2):113-23.
-
1991: Leclerc C; Deriaud E; Mimic V; van der Werf S
Identification of a T-cell epitope adjacent to neutralization antigenic site 1 of poliovirus type 1.
Journal of virology 1991;65(2):711-8.
-
1991: Martineau P; Charbit A; Leclerc C; Werts C; O'Callaghan D; Hofnung M
A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.
Bio/technology (Nature Publishing Company) 1991;9(2):170-2.
-
1991: Clement J M; Charbit A; Martineau P; O'Callaghan D; Szmelcman S; Leclerc C; Hofnung M
Bacterial vectors to target and/or purify polypeptides: their use in immunological studies.
Annales de biologie clinique 1991;49(4):249-54.
-
1990: Przewlocki G; Leclerc C
Role of major and minor histocompatibility antigens in the suppression of alloreactive cytotoxic responses induced by alloantigen pretreatment.
Research in immunology 1990;141(9):839-53.
-
1990: O'Callaghan D; Charbit A; Martineau P; Leclerc C; van der Werf S; Nauciel C; Hofnung M
Immunogenicity of foreign peptide epitopes expressed in bacterial envelope proteins.
Research in microbiology 1990;141(7-8):963-9.
-
1990: Leclerc C; Schutze M P; Deriaud E; Przewlocki G
The in vivo elimination of CD4+ T cells prevents the induction but not the expression of carrier-induced epitopic suppression.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(5):1343-9.
-
1990: van der Werf S; Charbit A; Leclerc C; Mimic V; Ronco J; Girard M; Hofnung M
Critical role of neighbouring sequences on the immunogenicity of the C3 poliovirus neutralization epitope expressed at the surface of recombinant bacteria.
Vaccine 1990;8(3):269-77.
-
1990: LeClerc C; Martineau P; Van der Werf S; Deriaud E; Duplay P; Hofnung M
Induction of virus-neutralizing antibodies by bacteria expressing the C3 poliovirus epitope in the periplasm. The route of immunization influences the isotypic distribution and the biologic activity of the antipoliovirus antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(8):3174-82.
-
1989: Schutze M P; Langlade-Demoyen P; Przewlocki G; Leclerc C
Alloantigen pretreatment induces a down-regulation of the in vivo subsequent development of cytotoxic T lymphocytes directed against linked alloantigens.
European journal of immunology 1989;19(8):1365-71.
-
1989: Leclerc C; Charbit A; Molla A; Hofnung M
Antibody response to a foreign epitope expressed at the surface of recombinant bacteria: importance of the route of immunization.
Vaccine 1989;7(3):242-8.
-
1989: Morgeaux S; Joffret M L; Leclerc C; Sureau P; Perrin P
Evaluation of the induction of specific cytotoxic T lymphocytes following immunization of F1 hybrid mice with rabies antigens.
Research in virology 1989;140(3):193-206.
-
1989: Schutze M P; Deriaud E; Przewlocki G; LeClerc C
Carrier-induced epitopic suppression is initiated through clonal dominance.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(8):2635-40.
-
1989: Leclerc C
Suppressor T cells: an appraisal of their role by in vivo elimination.
Research in immunology 1989;140(3):318-23; discussion 339-45.
-
1989: Leclerc C
Vaccination against HIV and SIV.
Current opinion in immunology 1989;2(3):428-32.
-
1988: Perrin P; Joffret M L; Oth D; Leclerc C; Sureau P; Thibodeau L
Interleukin-2 production in vitro: a new approach to the study of rabies vaccine immunogenicity as appraised by testing different glycoprotein presentations.
Vaccine 1988;6(4):331-8.
-
1988: Perrin P; Joffret M L; Leclerc C; Oth D; Sureau P; Thibodeau L
Interleukin 2 increases protection against experimental rabies.
Immunobiology 1988;177(2):199-209.
-
1988: Leclerc C; Deriaud E; Schutze M P; Chedid L
Prevention of low dose streptozotocin induced diabetes by muramyl dipeptide.
International journal of immunopharmacology 1988;10(3):293-8.
-
1987: Hosmalin A; Carelli C; Gaillard J; Lefrancier P; Drobecq H; Leclerc C; Amar O; Audibert F; Chedid L
Structural requirements for the induction of "immunological castration" by linear monomeric LHRH-lys-MDP administered in saline.
Clinical immunology and immunopathology 1987;45(3):447-60.
-
1987: Schutze M P; LeClerc C; Jolivet M; Deriaud E; Audibert F; Chang C C; Chedid L
A potential anti-pregnancy vaccine built by conjugation of the beta-subunit of human chorionic gonadotropin to adjuvant-active muramyl peptide.
American journal of reproductive immunology and microbiology : AJRIM 1987;14(3):84-90.
-
1987: Vogel F R; Leclerc C; Schutze M P; Jolivet M; Audibert F; Klein T W; Chedid L
Modulation of carrier-induced epitopic suppression by Bordetella pertussis components and muramyl peptide.
Cellular immunology 1987;107(1):40-51.
-
1987: Leclerc C; Przewlocki G; Schutze M P; Chedid L
A synthetic vaccine constructed by copolymerization of B and T cell determinants.
European journal of immunology 1987;17(2):269-73.
-
1987: Schutze M P; Leclerc C; Vogel F R; Chedid L
Epitopic suppression in synthetic vaccine models: analysis of the effector mechanisms.
Cellular immunology 1987;104(1):79-90.
-
1985: Schutze M P; Leclerc C; Jolivet M; Audibert F; Chedid L
Carrier-induced epitopic suppression, a major issue for future synthetic vaccines.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(4):2319-22.
-
1984: Leclerc C D; Audibert F M; Chedid L A; Deriaud E J; Masihi N K; Lederer E
Comparison of immunomodulatory activities in mice and guinea pigs of a synthetic desmuramyl peptidolipid triglymyc.
Infection and immunity 1984;43(3):870-5.
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