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Roland Leclercq

Research Profile

Chemicals & Drugs

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Roland Leclercq; Kenny Oberlé; Hélène Budzinski; Vincent Cattoir; Sébastien Galopin; Fabienne Petit
Changes in enterococcal populations and related antibiotic resistance along a medical center-wastewater treatment plant-river continuum.
Vincent Cattoir; Roland Leclercq
Twenty-five years of shared life with vancomycin-resistant enterococci: is it time to divorce?
François Lebreton; Roland Leclercq; Brunella Posteraro; maurizio Sanguinetti; Riccardo Torelli; Willem van Schaik; Nicolas Verneuil; Rob Willems; Xinglin Zhang; Anne Dhalluin; Jean-Christophe Giard; Florian Le Bras; Vincent Cattoir
AsrR is an oxidative stress sensing regulator modulating Enterococcus faecium opportunistic traits, antimicrobial resistance, and pathogenicity.

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All Publications

2013: Roland Leclercq; Kenny Oberlé; Hélène Budzinski; Vincent Cattoir; Sébastien Galopin; Fabienne Petit
Changes in enterococcal populations and related antibiotic resistance along a medical center-wastewater treatment plant-river continuum.
Applied and environmental microbiology 2013;79(7):2428-34.
2013: Vincent Cattoir; Roland Leclercq
Twenty-five years of shared life with vancomycin-resistant enterococci: is it time to divorce?
The Journal of antimicrobial chemotherapy 2013;68(4):731-42.
2012: François Lebreton; Roland Leclercq; Brunella Posteraro; maurizio Sanguinetti; Riccardo Torelli; Willem van Schaik; Nicolas Verneuil; Rob Willems; Xinglin Zhang; Anne Dhalluin; Jean-Christophe Giard; Florian Le Bras; Vincent Cattoir
AsrR is an oxidative stress sensing regulator modulating Enterococcus faecium opportunistic traits, antimicrobial resistance, and pathogenicity.
PLoS pathogens 2012;8(8):e1002834.
2011: Anne-Claire Gac; Xavier Le Coutour; Roland Leclercq; JJ Parienti; Sylvain Chantepie; Sabine Fradin; Oumedaly Reman
Dynamics of procalcitonin and bacteremia in neutropenic adults with acute myeloid leukemia.
Leukemia research 2011;35(10):1294-6.
2011: T-X Nhan; Roland Leclercq; Vincent Cattoir
Prevalence of toxin genes in consecutive clinical isolates of Staphylococcus aureus and clinical impact.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2011;30(6):719-25.
2011: Nancy Bourdon; Marguerite Fines-Guyon; Jean-Michel Thiolet; Sylvie Maugat; Bruno Coignard; Roland Leclercq; Vincent Cattoir
Changing trends in vancomycin-resistant enterococci in French hospitals, 2001-08.
The Journal of antimicrobial chemotherapy 2011;66(4):713-21.
2011: Brigitte Malbruny; Anja M Werno; David R Murdoch; Roland Leclercq; Vincent Cattoir
Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70.
Antimicrobial agents and chemotherapy 2011;55(4):1470-4.
2011: Christine Lascols; Patrick Legrand; A Mérens; Roland Leclercq; L Armand-Lefevre; Henri Drugeon; M D Kitzis; C Muller-Serieys; M E Reverdy; M Roussel-Delvallez; Carole Moubareck; A Lemire; A Miara; M Gjoklaj; Claude-James Soussy
In vitro antibacterial activity of doripenem against clinical isolates from French teaching hospitals: proposition of zone diameter breakpoints.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2011;30(4):475-82.
2011: Christine Lascols; Patrick Legrand; A Mérens; Roland Leclercq; C Muller-Serieys; Henri Drugeon; M D Kitzis; M E Reverdy; M Roussel-Delvallez; Carole Moubareck; S Brémont; A Miara; M Gjoklaj; Claude-James Soussy
In vitro antibacterial activity of ceftobiprole against clinical isolates from French teaching hospitals: proposition of zone diameter breakpoints.
International journal of antimicrobial agents 2011;37(3):235-9.
2011: Anne Le Bouter; Roland Leclercq; Vincent Cattoir
Molecular basis of resistance to macrolides, lincosamides and streptogramins in Staphylococcus saprophyticus clinical isolates.
International journal of antimicrobial agents 2011;37(2):118-23.
2011: François Lebreton; Roland Leclercq; Fany Reffuveille; Jean-Christophe Giard; Rabia Ladjouzi; Florian Le Bras; Vincent Cattoir
Galleria mellonella as a model for studying Enterococcus faecium host persistence.
Journal of molecular microbiology and biotechnology 2011;21(3-4):191-6.
2011: Nancy Bourdon; Astrid Lemire; Marguerite Fines-Guyon; Michel Auzou; Bruno Perichon; Patrice Courvalin; Vincent Cattoir; Roland Leclercq
Comparison of four methods, including semi-automated rep-PCR, for the typing of vancomycin-resistant Enterococcus faecium.
Journal of microbiological methods 2011;84(1):74-80.
2010: Christophe Rusniok; Elisabeth Couvé; Violette Da Cunha; Rachida El Gana; Nora Zidane; Christiane Bouchier; Claire Poyart; Roland Leclercq; Patrick Trieu-Cuot; Philippe Glaser
Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis.
Journal of bacteriology 2010;192(8):2266-76.
2009: Vincent Cattoir; Thi Mum Huynh; Nancy Bourdon; Michel Auzou; Roland Leclercq
Trimethoprim resistance genes in vancomycin-resistant Enterococcus faecium clinical isolates from France.
International journal of antimicrobial agents 2009;34(4):390-2.
2009: Leyla Boumghar-Bourtchaï; Anne Dhalluin; Brigitte Malbruny; Sébastien Galopin; Roland Leclercq
Influence of recombination on development of mutational resistance to linezolid in Enterococcus faecalis JH2-2.
Antimicrobial agents and chemotherapy 2009;53(9):4007-9.
2009: Leyla Boumghar-Bourtchai; Hubert Chardon; Brigitte Malbruny; Senda Mezghani; Roland Leclercq; Anne Dhalluin
Resistance to macrolides by ribosomal mutation in clinical isolates of Turicella otitidis.
International journal of antimicrobial agents 2009;34(3):274-7.
2009: Sébastien Galopin; Vincent Cattoir; Roland Leclercq
A chromosomal chloramphenicol acetyltransferase determinant from a probiotic strain of Bacillus clausii.
FEMS microbiology letters 2009;296(2):185-9.
2009: Roland Leclercq
Epidemiological and resistance issues in multidrug-resistant staphylococci and enterococci.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2009;15(3):224-31.
2008: Adeline Achard; Véronique Guérin-Faublée; Vianney Pichereau; Corinne Villers; Roland Leclercq
Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene.
Antimicrobial agents and chemotherapy 2008;52(8):2767-70.
2008: I Proudy; D Bouglé; Roland Leclercq; Michel Vergnaud
Tracing of Enterobacter sakazakii isolates in infant milk formula processing by BOX-PCR genotyping.
Journal of applied microbiology 2008;105(2):550-8.
2008: Caroline Piau; J Jehan; Roland Leclercq; C Daurel
Catalase-negative Staphylococcus aureus strain with point mutations in the katA gene.
Journal of clinical microbiology 2008;46(6):2060-1.
2008: Roland Leclercq; C Goulenok; V Loncle-Provot
[Use of a program-specific website to disseminate data on antimicrobial susceptibility of clinical isolates from the Tigecycline Evaluation and Surveillance Trial (TEST)].
Médecine et maladies infectieuses 2008;38(3):133-40.
2008: Wafa Achour; O Bouchami; S Galopin; Roland Leclercq; Assia Ben Hassen
Analysis of pristinamycin-resistant Staphylococcus epidermidis isolates in the Tunisian Bone Marrow Transplant Center.
Letters in applied microbiology 2008;46(3):358-63.
2008: Efi Petinaki; Véronique Guérin-Faublée; Vianney Pichereau; Corinne Villers; Adeline Achard; Brigitte Malbruny; Roland Leclercq
Lincomycin resistance gene lnu(D) in Streptococcus uberis.
Antimicrobial agents and chemotherapy 2008;52(2):626-30.
2008: Claire Daurel; Corinne Huet; Anne Dhalluin; Michèle Bes; Jerome Etienne; Roland Leclercq
Differences in potential for selection of clindamycin-resistant mutants between inducible erm(A) and erm(C) Staphylococcus aureus genes.
Journal of clinical microbiology 2008;46(2):546-50.
2008: I Proudy; D Bouglé; Emmanuel Coton; Monika Coton; Roland Leclercq; Michel Vergnaud
Genotypic characterization of Enterobacter sakazakii isolates by PFGE, BOX-PCR and sequencing of the fliC gene.
Journal of applied microbiology 2008;104(1):26-34.
2007: Claire Daurel; Anne-Laure Prunier; Françoise Chau; Louis Garry; Roland Leclercq; Bruno Fantin
Role of hypermutability on bacterial fitness and emergence of resistance in experimental osteomyelitis due to Staphylococcus aureus.
FEMS immunology and medical microbiology 2007;51(2):344-9.
2007: Adeline Achard; Roland Leclercq
Characterization of a small mobilizable transposon, MTnSag1, in Streptococcus agalactiae.
Journal of bacteriology 2007;189(11):4328-31.
2007: Vincent Cattoir; Lilia Merabet; Patrick Legrand; Claude-James Soussy; Roland Leclercq
Emergence of a Streptococcus pneumoniae isolate resistant to streptogramins by mutation in ribosomal protein L22 during pristinamycin therapy of pneumococcal pneumonia.
The Journal of antimicrobial chemotherapy 2007;59(5):1010-2.
2007: Florence Depardieu; Isabelle Podglajen; Roland Leclercq; Ekkehard Collatz; Patrice Courvalin
Modes and modulations of antibiotic resistance gene expression.
Clinical microbiology reviews 2007;20(1):79-114.
2006: Sana Ben Nsira; Michel Dupuis; Roland Leclercq
Evaluation of MRSA Select, a new chromogenic medium for the detection of nasal carriage of methicillin-resistant Staphylococcus aureus.
International journal of antimicrobial agents 2006;27(6):561-4.
2006: Pierre Charbonneau; JJ Parienti; Pascal Thibon; Michel Ramakers; Cédric Daubin; Damien du Cheyron; Guy Lebouvier; Xavier Le Coutour; Roland Leclercq
Fluoroquinolone use and methicillin-resistant Staphylococcus aureus isolation rates in hospitalized patients: a quasi experimental study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(6):778-84.
2006: Albertine Léon; Stephane Pronost; Jackie Tapprest; Nathalie Foucher; Béatrice Blanchard; Geneviève André-Fontaine; Claire Laugier; Guillaume Fortier; Roland Leclercq
Identification of pathogenic Leptospira strains in tissues of a premature foal by use of polymerase chain reaction analysis.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2006;18(2):218-21.
2006: Michel Dupuis; Roland Leclercq
Activity of a new oral streptogramin, XRP2868, against gram-positive cocci harboring various mechanisms of resistance to streptogramins.
Antimicrobial agents and chemotherapy 2006;50(1):237-42.
2005: Didier Guillemot; Roland Leclercq
[Impact of population exposure on the risk of bacterial resistance].
Médecine et maladies infectieuses 2005;35 Suppl 3():S212-20.
2005: Catherine Cordonnier; Raoul Herbrecht; Agnès Buzyn; Guy Leverger; Roland Leclercq; Gérard Nitenberg; Sylvie Bastuji-Garin
Risk factors for Gram-negative bacterial infections in febrile neutropenia.
Haematologica 2005;90(8):1102-9.
2005: Adeline Achard; Corinne Villers; Vianney Pichereau; Roland Leclercq
New lnu(C) gene conferring resistance to lincomycin by nucleotidylation in Streptococcus agalactiae UCN36.
Antimicrobial agents and chemotherapy 2005;49(7):2716-9.
2005: Pierre Charbonneau; JJ Parienti; Pascal Thibon; G Lebouvier; Roland Leclercq
[Fluoroquinolone use and MRSA rates in hospitalized patients].
Médecine et maladies infectieuses 2005;35 Suppl 2():S35-7.
2005: Anne-Laure Prunier; Roland Leclercq
Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus.
Journal of bacteriology 2005;187(10):3455-64.
2005: Hiep N'Guyen Trong; Anne-Laure Prunier; Roland Leclercq
Hypermutable and fluoroquinolone-resistant clinical isolates of Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2005;49(5):2098-101.
2005: Roland Leclercq; Corinne Huet; Mélanie Picherot; Patrick Trieu-Cuot; Claire Poyart
Genetic basis of antibiotic resistance in clinical isolates of Streptococcus gallolyticus (Streptococcus bovis).
Antimicrobial agents and chemotherapy 2005;49(4):1646-8.
2005: Johan Van Eldere; E Meekers; Katrien Lagrou; Caroline Massonet; Annie Canu; I Devenyns; Jan Verhaegen; G Syrogiannopoulos; Roland Leclercq
Macrolide-resistance mechanisms in Streptococcus pneumoniae isolates from Belgium.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2005;11(4):332-4.
2005: Anne-Laure Prunier; Hiep N'Guyen Trong; Didier Tande; Christine Segond; Roland Leclercq
Mutation of L4 ribosomal protein conferring unusual macrolide resistance in two independent clinical isolates of Staphylococcus aureus.
Microbial drug resistance (Larchmont, N.Y.) 2005;11(1):18-20.
2004: Brigitte Malbruny; Anja M Werno; Trevor P Anderson; David R Murdoch; Roland Leclercq
A new phenotype of resistance to lincosamide and streptogramin A-type antibiotics in Streptococcus agalactiae in New Zealand.
The Journal of antimicrobial chemotherapy 2004;54(6):1040-4.
2004: Gervais Clarebout; E Nativelle; B Bozdogan; Corinne Villers; Roland Leclercq
Bactericidal activity of quinupristin-dalfopristin against strains of Staphylococcus aureus with the MLS(B) phenotype of resistance according to the erm gene type.
International journal of antimicrobial agents 2004;24(5):444-9.
2004: Wafa Achour; Olfa Guenni; Marguerite Fines; Roland Leclercq; Assia Ben Hassen
rpoB mutations in Streptococcus mitis clinical isolates resistant to rifampin.
Antimicrobial agents and chemotherapy 2004;48(7):2757-9.
2004: Wafa Achour; Olfa Guenni; Brigitte Malbruny; Annie Canu; Roland Leclercq; Assia Ben Hassen
Phenotypic and molecular characterization of macrolide and streptogramin resistance in Streptococcus mitis from neutropenic patients.
The Journal of antimicrobial chemotherapy 2004;54(1):117-21.
2004: D Guillernot; P Weber; Roland Leclercq
[Impact of population exposure on the selection of bacterial resistance].
Médecine et maladies infectieuses 2004;34 Suppl 1():S106-8.
2004: Véronique David; Bülent Bozdogan; Jean-Luc Mainardi; Raymond Legrand; Laurent Gutmann; Roland Leclercq
Mechanism of intrinsic resistance to vancomycin in Clostridium innocuum NCIB 10674.
Journal of bacteriology 2004;186(11):3415-22.
2004: JJ Parienti; Damien du Cheyron; Michel Ramakers; Brigitte Malbruny; Roland Leclercq; Xavier Le Coutour; Pierre Charbonneau
Alcoholic povidone-iodine to prevent central venous catheter colonization: A randomized unit-crossover study.
Critical care medicine 2004;32(3):708-13.
2004: C Muller-Serieys; Henri Drugeon; Jerome Etienne; Christine Lascols; Roland Leclercq; J Nguyen; Claude-James Soussy
Activity of linezolid against Gram-positive cocci isolated in French hospitals as determined by three in-vitro susceptibility testing methods.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2004;10(3):242-6.
2004: Annie Canu; Ahmed Abbas; Brigitte Malbruny; François Sichel; Roland Leclercq
Denaturing high-performance liquid chromatography detection of ribosomal mutations conferring macrolide resistance in gram-positive cocci.
Antimicrobial agents and chemotherapy 2004;48(1):297-304.
2003: Damien du Cheyron; A Lesage; Olivier Le Page; F Flais; Roland Leclercq; Pierre Charbonneau
Corticosteroids as adjunctive treatment in Austrian's syndrome (pneumococcal endocarditis, meningitis, and pneumonia): report of two cases and review of the literature.
Journal of clinical pathology 2003;56(11):879-81.
2003: Claude-James Soussy; J Nguyen; Fred W Goldstein; Henri Dabernat; A Andremont; Roland Leclercq; Henri Drugeon; P Cavallo; Hubert Chardon; Jerome Etienne; Yves Rio; P Courvalin
In vitro antibacterial activity of moxifloxacin against hospital isolates: a multicentre study.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2003;9(10):997-1005.
2003: Julia Dina; Brigitte Malbruny; Roland Leclercq
Nonsense mutations in the lsa-like gene in Enterococcus faecalis isolates susceptible to lincosamides and Streptogramins A.
Antimicrobial agents and chemotherapy 2003;47(7):2307-9.
2003: Anne-Laure Prunier; Brigitte Malbruny; Muriel Laurans; Jacques Brouard; Jean-François Duhamel; Roland Leclercq
High rate of macrolide resistance in Staphylococcus aureus strains from patients with cystic fibrosis reveals high proportions of hypermutable strains.
The Journal of infectious diseases 2003;187(11):1709-16.
2003: Bülent Bozdogan; Sébastien Galopin; Guy Gerbaud; Patrice Courvalin; Roland Leclercq
Chromosomal aadD2 encodes an aminoglycoside nucleotidyltransferase in Bacillus clausii.
Antimicrobial agents and chemotherapy 2003;47(4):1343-6.
2003: Catherine Cordonnier; Agnès Buzyn; Guy Leverger; Raoul Herbrecht; Mathilde Hunault; Roland Leclercq; Sylvie Bastuji-Garin
Epidemiology and risk factors for gram-positive coccal infections in neutropenia: toward a more targeted antibiotic strategy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(2):149-58.
2002: Juliette Pavie; Agnès Lefort; Virginie Zarrouk; Françoise Chau; Louis Garry; Roland Leclercq; Bruno Fantin
Efficacies of quinupristin-dalfopristin combined with vancomycin in vitro and in experimental endocarditis due to methicillin-resistant Staphylococcus aureus in relation to cross-resistance to macrolides, lincosamides, and streptogramin B- type antibiotics.
Antimicrobial agents and chemotherapy 2002;46(9):3061-4.
2002: Anne-Laure Prunier; Brigitte Malbruny; Didier Tandé; Bertrand Picard; Roland Leclercq
Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides.
Antimicrobial agents and chemotherapy 2002;46(9):3054-6.
2002: Gervais Clarebout; Roland Leclercq
Fluorescence assay for studying the ability of macrolides to induce production of ribosomal methylase.
Antimicrobial agents and chemotherapy 2002;46(7):2269-72.
2002: Brigitte Malbruny; Annie Canu; Bülent Bozdogan; Bruno Fantin; Virginie Zarrouk; Sylvie Dutka-Malen; Celine Feger; Roland Leclercq
Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2002;46(7):2200-7.
2002: Brigitte Malbruny; Kensuke Nagai; Maëlle Coquemont; Bülent Bozdogan; Arjana Tambic Andrasevic; Helena Hupkova; Roland Leclercq; Peter C Appelbaum
Resistance to macrolides in clinical isolates of Streptococcus pyogenes due to ribosomal mutations.
The Journal of antimicrobial chemotherapy 2002;49(6):935-9.
2002: Sylvie Dargere; Michel Vergnaud; Renaud Verdon; Eric Saloux; Olivier Le Page; Roland Leclercq; Claude Bazin
Enterococcus gallinarum endocarditis occurring on native heart valves.
Journal of clinical microbiology 2002;40(6):2308-10.
2002: Edouard Bingen; Roland Leclercq; Franck Fitoussi; Naima Brahimi; Brigitte Malbruny; Dominique Deforche; Robert Cohen
Emergence of group A streptococcus strains with different mechanisms of macrolide resistance.
Antimicrobial agents and chemotherapy 2002;46(5):1199-203.
2002: Roland Leclercq
Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;34(4):482-92.
2002: Annie Canu; Brigitte Malbruny; Maëlle Coquemont; Todd A Davies; Peter C Appelbaum; Roland Leclercq
Diversity of ribosomal mutations conferring resistance to macrolides, clindamycin, streptogramin, and telithromycin in Streptococcus pneumoniae.
Antimicrobial agents and chemotherapy 2002;46(1):125-31.
2001: Roland Leclercq; MH Nicolas-Chanoine; patrice nordmann; Alain Philippon; P Marchais; A Buu-Ho; Hubert Chardon; Henri Dabernat; F Doucet-Populaire; C Grasmick; P Legrand; C Muller-Serieys; J Nguyen; Marie-Cécile Ploy; Marie-Elisabeth Reverdy; M Weber; R J Courcol
Multicenter evaluation of an automated system using selected bacteria that harbor challenging and clinically relevant mechanisms of resistance to antibiotics.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2001;20(9):626-35.
2001: Marguerite Fines; M Gueudin; A Ramon; Roland Leclercq
In vitro selection of resistance to clindamycin related to alterations in the attenuator of the erm(TR) gene of Streptococcus pyogenes UCN1 inducibly resistant to erythromycin.
The Journal of antimicrobial chemotherapy 2001;48(3):411-6.
2001: Annie Canu; Roland Leclercq
Overcoming bacterial resistance by dual target inhibition: the case of streptogramins.
Current drug targets. Infectious disorders 2001;1(2):215-25.
2001: Marguerite Fines; Stephane Pronost; K Maillard; Saíd Taouji; Roland Leclercq
Characterization of mutations in the rpoB gene associated with rifampin resistance in Rhodococcus equi isolated from foals.
Journal of clinical microbiology 2001;39(8):2784-7.
2001: Gervais Clarebout; Corinne Villers; Roland Leclercq
Macrolide resistance gene mreA of Streptococcus agalactiae encodes a flavokinase.
Antimicrobial agents and chemotherapy 2001;45(8):2280-6.
2001: Virginie Zarrouk; Bülent Bozdogan; Roland Leclercq; Louis Garry; Celine Feger; Claude Carbon; Bruno Fantin
Activities of the combination of quinupristin-dalfopristin with rifampin in vitro and in experimental endocarditis due to Staphylococcus aureus strains with various phenotypes of resistance to macrolide-lincosamide-streptogramin antibiotics.
Antimicrobial agents and chemotherapy 2001;45(4):1244-8.
2001: Gervais Clarebout; E Nativelle; Roland Leclercq
Unusual inducible cross resistance to macrolides, lincosamides, and streptogramins B by methylase production in clinical isolates of Staphylococcus aureus.
Microbial drug resistance (Larchmont, N.Y.) 2001;7(4):317-22.
2000: Claude-James Soussy; G Carret; Jean-Didier Cavallo; Hubert Chardon; C Chidiac; P Choutet; P Courvalin; Henri Dabernat; Henri Drugeon; Luc Dubreuil; Fred W Goldstein; V Jarlier; Roland Leclercq; MH Nicolas-Chanoine; Alain Philippon; C Quentin; Bernard Rouveix; Jacques Sirot
[Antibiogram Committee of the French Microbiology Society. Report 2000-2001].
Pathologie-biologie 2000;48(9):832-71.
2000: P Angot; Michel Vergnaud; M Auzou; Roland Leclercq
Macrolide resistance phenotypes and genotypes in French clinical isolates of Streptococcus pneumoniae. Observatoire de Normandie du Pneumocoque.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2000;19(10):755-8.
2000: Marguerite Fines; Roland Leclercq
Activity of linezolid against Gram-positive cocci possessing genes conferring resistance to protein synthesis inhibitors.
The Journal of antimicrobial chemotherapy 2000;45(6):797-802.
2000: Michel Vergnaud; J N Prévost; Brigitte Malbruny; J Brun; Roland Leclercq
Isolation in France of a clinical strain of Streptoccus pneumoniae susceptible to amoxycillin and resistant to cefotaxime.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2000;6(5):283-4.
2000: M Dowzicky; George H Talbot; Celine Feger; P Prokocimer; Jerome Etienne; Roland Leclercq
Characterization of isolates associated with emerging resistance to quinupristin/dalfopristin (Synercid) during a worldwide clinical program.
Diagnostic microbiology and infectious disease 2000;37(1):57-62.
2000: Virginie Zarrouk; Bülent Bozdogan; Roland Leclercq; Louis Garry; Claude Carbon; Bruno Fantin
Influence of resistance to streptogramin A type antibiotics on the activity of quinupristin-dalfopristin in vitro and in experimental endocarditis due to Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2000;44(5):1168-73.
2000: Roland Leclercq; R Bismuth; Isabelle Casin; Jean-Didier Cavallo; J Croizé; Annie Felten; F Goldstein; H Monteil; C Quentin-Noury; Marie-Elisabeth Reverdy; Michel Vergnaud; R Roiron
In vitro activity of fusidic acid against streptococci isolated from skin and soft tissue infections.
The Journal of antimicrobial chemotherapy 2000;45(1):27-9.
1999: Bülent Bozdogan; Roland Leclercq
Effects of genes encoding resistance to streptogramins A and B on the activity of quinupristin-dalfopristin against Enterococcus faecium.
Antimicrobial agents and chemotherapy 1999;43(11):2720-5.
1999: Bülent Bozdogan; Roland Leclercq; Alain Lozniewski; M Weber
Plasmid-mediated coresistance to streptogramins and vancomycin in Enterococcus faecium HM1032.
Antimicrobial agents and chemotherapy 1999;43(8):2097-8.
1999: Gerard Lina; A Quaglia; Marie-Elisabeth Reverdy; Roland Leclercq; François Vandenesch; Jerome Etienne
Distribution of genes encoding resistance to macrolides, lincosamides, and streptogramins among staphylococci.
Antimicrobial agents and chemotherapy 1999;43(5):1062-6.
1999: Adriana Rosato; H Vicarini; Roland Leclercq
Inducible or constitutive expression of resistance in clinical isolates of streptococci and enterococci cross-resistant to erythromycin and lincomycin.
The Journal of antimicrobial chemotherapy 1999;43(4):559-62.
1999: Bülent Bozdogan; L Berrezouga; Ming-Shang Kuo; David A Yurek; K A Farley; Brian J Stockman; Roland Leclercq
A new resistance gene, linB, conferring resistance to lincosamides by nucleotidylation in Enterococcus faecium HM1025.
Antimicrobial agents and chemotherapy 1999;43(4):925-9.
1998: Roland Leclercq; P Courvalin
Streptogramins: an answer to antibiotic resistance in gram-positive bacteria.
Lancet 1998;352(9128):591-2.
1998: Adriana Rosato; H Vicarini; Alain Bonnefoy; JF Chantot; Roland Leclercq
A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin.
Antimicrobial agents and chemotherapy 1998;42(6):1392-6.
1997: Hélène Aubry-Damon; Patrick Legrand; Christian Brun-Buisson; alain astier; Claude-James Soussy; Roland Leclercq
Reemergence of gentamicin-susceptible strains of methicillin-resistant Staphylococcus aureus: roles of an infection control program and changes in aminoglycoside use.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;25(3):647-53.
1997: Bruno Fantin; Roland Leclercq; Louis Garry; Claude Carbon
Influence of inducible cross-resistance to macrolides, lincosamides, and streptogramin B-type antibiotics in Enterococcus faecium on activity of quinupristin-dalfopristin in vitro and in rabbits with experimental endocarditis.
Antimicrobial agents and chemotherapy 1997;41(5):931-5.
1997: Roland Leclercq; P Courvalin
Resistance to glycopeptides in enterococci.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;24(4):545-54; quiz 555-6.
1997: H Vicarini; Adriana Rosato; Roland Leclercq
Analysis of regulatory region of ermAM genes in streptococci and enterococci highly resistant to macrolides and lincosamides.
Advances in experimental medicine and biology 1997;418():495-8.
1997: Bülent Bozdogan; L Berrezouga; Roland Leclercq
Resistance to lincosamides by nucleotidylation associated with conjugative transfer of a large chromosomal element in Enterococcus faecium.
Advances in experimental medicine and biology 1997;418():491-3.
1997: Roland Leclercq
Antibiotic resistance in streptococci and enterococci. Where are we, where are we going? An opening lecture.
Advances in experimental medicine and biology 1997;418():419-27.
1997: Roland Leclercq
Enterococci acquire new kinds of resistance.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;24 Suppl 1():S80-4.
1997: Michel Arthur; Florence Depardieu; Guy Gerbaud; Marc Galimand; Roland Leclercq; Patrice Courvalin
The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction.
Journal of bacteriology 1997;179(1):97-106.
1996: C Lawrence; M Cosseron; P Durand; Y Costa; Roland Leclercq
Consecutive isolation of homologous strains of methicillin-resistant and methicillin-susceptible Staphylococcus aureus from a hospitalized child.
The Journal of hospital infection 1996;33(1):49-53.
1996: C Lawrence; M Cosseron; Olivier Mimoz; Christian Brun-Buisson; Y Costa; K Samii; J Duval; Roland Leclercq
Use of the coagulase gene typing method for detection of carriers of methicillin-resistant Staphylococcus aureus.
The Journal of antimicrobial chemotherapy 1996;37(4):687-96.
1996: S Ladeb; B Durand-Gasselin; Roland Leclercq; alain astier; Catherine Cordonnier
[Bacterial resistance and management of nosocomial infections: relations to hematology].
Pathologie-biologie 1996;44(2):107-12.
1996: Roland Leclercq
Epidemiology and control of multiresistant enterococci.
Drugs 1996;52 Suppl 2():47-9.
1995: Roland Leclercq; J Duval
[Bactericidal activity of combinations of ticarcillin-clavulanic acid or other beta-lactams (amoxicillin, piperacillin-tazobactam, ticarcillin) with gentamicin against Enterococcus faecalis and E. faecium].
Pathologie-biologie 1995;43(4):245-52.
1995: B Durand-Gasselin; Roland Leclercq; F Girard-Pipau; M C Deharvengt; H Rochant; alain astier; J Duval; Catherine Cordonnier
Evolution of bacterial susceptibility to antibiotics during a six-year period in a haematology unit.
The Journal of hospital infection 1995;29(1):19-33.
1993: R Rende-Fournier; Roland Leclercq; Marc Galimand; J Duval; Patrice Courvalin
Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145.
Antimicrobial agents and chemotherapy 1993;37(10):2119-25.
1993: Y Costa; Marc Galimand; Roland Leclercq; J Duval; Patrice Courvalin
Characterization of the chromosomal aac(6')-Ii gene specific for Enterococcus faecium.
Antimicrobial agents and chemotherapy 1993;37(9):1896-903.
1993: Jacques Tankovic; Roland Leclercq; J Duval
Antimicrobial susceptibility of Pediococcus spp. and genetic basis of macrolide resistance in Pediococcus acidilactici HM3020.
Antimicrobial agents and chemotherapy 1993;37(4):789-92.
1993: R Menard; C Molinas; Michel Arthur; J Duval; Patrice Courvalin; Roland Leclercq
Overproduction of 3'-aminoglycoside phosphotransferase type I confers resistance to tobramycin in Escherichia coli.
Antimicrobial agents and chemotherapy 1993;37(1):78-83.
1992: Roland Leclercq; S Dutka-Malen; A Brisson-Noël; C Molinas; E Derlot; Michel Arthur; J Duval; Patrice Courvalin
Resistance of enterococci to aminoglycosides and glycopeptides.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1992;15(3):495-501.
1992: Roland Leclercq; S Dutka-Malen; J Duval; Patrice Courvalin
Vancomycin resistance gene vanC is specific to Enterococcus gallinarum.
Antimicrobial agents and chemotherapy 1992;36(9):2005-8.
1992: Roland Leclercq; L Nantas; Claude-James Soussy; J Duval
Activity of RP 59500, a new parenteral semisynthetic streptogramin, against staphylococci with various mechanisms of resistance to macrolide-lincosamide-streptogramin antibiotics.
The Journal of antimicrobial chemotherapy 1992;30 Suppl A():67-75.
1992: Roland Leclercq; R Bismuth; J Duval
New high-content disks for determination of high-level aminoglycoside resistance in clinical isolates of Enterococcus faecalis.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1992;11(4):356-60.
1991: Roland Leclercq; Patrice Courvalin
Intrinsic and unusual resistance to macrolide, lincosamide, and streptogramin antibiotics in bacteria.
Antimicrobial agents and chemotherapy 1991;35(7):1273-6.
1991: Roland Leclercq; Patrice Courvalin
Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification.
Antimicrobial agents and chemotherapy 1991;35(7):1267-72.
1991: Roland Leclercq; Edouard Bingen; Q H Su; N Lambert-Zechovski; Patrice Courvalin; J Duval
Effects of combinations of beta-lactams, daptomycin, gentamicin, and glycopeptides against glycopeptide-resistant enterococci.
Antimicrobial agents and chemotherapy 1991;35(1):92-8.
1990: S Dutka-Malen; Roland Leclercq; V Coutant; J Duval; Patrice Courvalin
Phenotypic and genotypic heterogeneity of glycopeptide resistance determinants in gram-positive bacteria.
Antimicrobial agents and chemotherapy 1990;34(10):1875-9.
1990: A Brisson-Noël; S Dutka-Malen; C Molinas; Roland Leclercq; Patrice Courvalin
Cloning and heterospecific expression of the resistance determinant vanA encoding high-level resistance to glycopeptides in Enterococcus faecium BM4147.
Antimicrobial agents and chemotherapy 1990;34(5):924-7.
1989: Roland Leclercq; F Bauduret; Claude-James Soussy
[Selection of constitutive mutants of gram-positive cocci inducible resistant to macrolides, lincosamides and streptogramins (MLS): comparison of the selective effects of the MLS].
Pathologie-biologie 1989;37(5 Pt 2):568-72.
1989: Claude-James Soussy; Roland Leclercq; L Deforges; J Duval
[In vitro antibacterial activity of a new fluoroquinolone, fleroxacin as a function of the sensitivity or resistance to nalidixic acid and to pefloxacin].
Pathologie-biologie 1989;37(5):364-9.
1989: Roland Leclercq; E Derlot; M Weber; J Duval; Patrice Courvalin
Transferable vancomycin and teicoplanin resistance in Enterococcus faecium.
Antimicrobial agents and chemotherapy 1989;33(1):10-5.
1988: Roland Leclercq; E Derlot; J Duval; Patrice Courvalin
Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium.
The New England journal of medicine 1988;319(3):157-61.
1988: Roland Leclercq; S Besbes; Claude-James Soussy
[Resistance of nongroupable streptococci to beta-lactams. Detection by antibiogram and the activity of combinations of penicillin G and gentamicin].
Pathologie-biologie 1988;36(5 Pt 2):626-31.
1988: Claude-James Soussy; Roland Leclercq; J Duval
[In vitro antibacterial activity of piperacillin/quinolone combinations].
Pathologie-biologie 1988;36(5):357-60.
1988: Claude-James Soussy; Roland Leclercq; J Duval
[In vitro antibacterial activity of a new macrolide: miokamycin. Comparison with erythromycin and josamycin].
Pathologie-biologie 1988;36(5):370-6.
1987: Roland Leclercq; A Brisson-Noël; J Duval; Patrice Courvalin
Phenotypic expression and genetic heterogeneity of lincosamide inactivation in Staphylococcus spp.
Antimicrobial agents and chemotherapy 1987;31(12):1887-91.