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Cécile Lecoeur

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Genes & Molecular Sequences

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France

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Amélie Bonnefond; Franck De Graeve; Aurélie Dechaume; Jérôme Delplanque; Emmanuelle Durand; Isabelle Fajardy; Beverley Balkau; Marlène Huyvaert; David Le Guilcher; Cécile Lecoeur; Michel Marre; Louise Montagne; Julien Philippe; Olivier Sand; Anne Vambergue; Vincent Vatin; Martine Vaxillaire; philippe froguel
Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene.
Marie Boutant; philippe froguel; Marjo-Riitta Jarvelin; Cécile Lecoeur; Anaïs Perilhou; Julien Philippe; Oscar Henrique Pereira Ramos; Donald Scott; Sylvain Sebert; Emmanuel Vaillant; Beatriz Valcarcel; Martine Vaxillaire; Pili Zhang; Beverley Balkau; Mireille Vasseur-Cognet
Glucose-dependent regulation of NR2F2 promoter and influence of SNP-rs3743462 on whole body insulin sensitivity.
philippe froguel; Rosa-Maria Guéant-Rodriguez; Bernard Herbeth; Peter Jacobson; Marjo-Riitta Jarvelin; Yann Labrune; Michel R Langlois; Cécile Lecoeur; Claudio Maffeis; David Meyre; Anita Morandi; Ndeye Coumba Ndiaye; Aimo Ruokonen; Gérard Siest; Lars Sjöström; Maria G Stathopoulou; Amélie Bonnefond; Leonardo Bottolo; Nabila Bouatia-Naji; Lena M S Carlsson; Aurélie Dechaume; George V Dedoussis; Joris R Delanghe; Said El Shamieh; Paul Elliott; Mario Falchi; Andrew Walley; Sophie Visvikis-Siest
A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.

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All Publications

2012: Amélie Bonnefond; Franck De Graeve; Aurélie Dechaume; Jérôme Delplanque; Emmanuelle Durand; Isabelle Fajardy; Beverley Balkau; Marlène Huyvaert; David Le Guilcher; Cécile Lecoeur; Michel Marre; Louise Montagne; Julien Philippe; Olivier Sand; Anne Vambergue; Vincent Vatin; Martine Vaxillaire; philippe froguel
Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene.
PloS one 2012;7(6):e37423.
2012: Marie Boutant; philippe froguel; Marjo-Riitta Jarvelin; Cécile Lecoeur; Anaïs Perilhou; Julien Philippe; Oscar Henrique Pereira Ramos; Donald Scott; Sylvain Sebert; Emmanuel Vaillant; Beatriz Valcarcel; Martine Vaxillaire; Pili Zhang; Beverley Balkau; Mireille Vasseur-Cognet
Glucose-dependent regulation of NR2F2 promoter and influence of SNP-rs3743462 on whole body insulin sensitivity.
PloS one 2012;7(5):e35810.
2012: philippe froguel; Rosa-Maria Guéant-Rodriguez; Bernard Herbeth; Peter Jacobson; Marjo-Riitta Jarvelin; Yann Labrune; Michel R Langlois; Cécile Lecoeur; Claudio Maffeis; David Meyre; Anita Morandi; Ndeye Coumba Ndiaye; Aimo Ruokonen; Gérard Siest; Lars Sjöström; Maria G Stathopoulou; Amélie Bonnefond; Leonardo Bottolo; Nabila Bouatia-Naji; Lena M S Carlsson; Aurélie Dechaume; George V Dedoussis; Joris R Delanghe; Said El Shamieh; Paul Elliott; Mario Falchi; Andrew Walley; Sophie Visvikis-Siest
A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.
PloS one 2012;7(3):e32327.
2011: Hélène Choquet; Yann Labrune; Franck De Graeve; Anke Hinney; Johannes Hebebrand; André Scherag; Cécile Lecoeur; Maithé Tauber; Beverley Balkau; Paul Elliot; Marjo-Riitta Jarvelin; Andrew J Walley; Philippe Besnard; philippe froguel; David Meyre
Lack of association of CD36 SNPs with early onset obesity: a meta-analysis in 9,973 European subjects.
Obesity (Silver Spring, Md.) 2011;19(4):833-9.
2010: Maya Ghoussaini; Fanny Stutzmann; Cyril Couturier; Vincent Vatin; Emmanuelle Durand; Cécile Lecoeur; Franck Degraeve; Barbara Heude; Maithé Tauber; Serge Hercberg; Claire Levy-Marchal; Patrick Tounian; Jacques Weill; Michael Traurig; Clifton Bogardus; Leslie J Baier; Jacques L Michaud; philippe froguel; David Meyre
Analysis of the SIM1 contribution to polygenic obesity in the French population.
Obesity (Silver Spring, Md.) 2010;18(8):1670-5.
2010: Odile Poulain-Godefroy; Olivier Le Bacquer; Pauline Plancq; Cécile Lecoeur; François Pattou; Gema Frühbeck; philippe froguel
Inflammatory role of Toll-like receptors in human and murine adipose tissue.
Mediators of inflammation 2010;2010():823486.
2009: Hélène Choquet; Christine Cavalcanti-Proença; Cécile Lecoeur; Christian Dina; Stéphane Cauchi; Martine Vaxillaire; Samy HADJADJ; Fritz F Horber; Natascha Potoczna; Guillaume Charpentier; Juan Ruiz; Serge Hercberg; Suliya Maimaitiming; Ronan Roussel; Michael Boenhnke; Anne U Jackson; Wolfgang Patsch; Franz Krempler; Benjamin F Voight; David Altshuler; Leif Groop; Gudmar Thorleifsson; Valgerdur Steinthorsdottir; Kari Stefansson; Beverley Balkau; philippe froguel; David Meyre
The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects.
Human molecular genetics 2009;18(13):2495-501.
2009: Vera Rocha Perugini; Muriel Lavie; David Delgrange; Jonathan Canton; André Pillez; Julie Potel; Cécile Lecoeur; Eric Rubinstein; Jean Dubuisson; Czeslaw Wychowski; Laurence Cocquerel
The association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entry.
BMC microbiology 2009;9():111.
2009: Maria Gueorguiev; Cécile Lecoeur; M Benzinou; Charles A Mein; D Meyre; V Vatin; Jacques Weill; B Heude; Ashley B Grossman; philippe froguel; Marta Korbonits
A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature.
Annals of human genetics 2009;73(1):1-9.
2008: POULAIN-GODEFROY Odile; Cécile Lecoeur; François Pattou; Gema Frühbeck; philippe froguel
Inflammation is associated with a decrease of lipogenic factors in omental fat in women.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(1):R1-7.
2008: Michael Benzinou; Jean-Claude Chèvre; Kirsten J Ward; Cécile Lecoeur; Christian Dina; Stephane Lobbens; Emmanuelle Durand; Jérôme Delplanque; Fritz F Horber; Barbara Heude; Beverley Balkau; Knut Borch-Johnsen; Torben Jørgensen; Torben Hansen; Oluf Pedersen; David Meyre; philippe froguel
Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations.
Human molecular genetics 2008;17(13):1916-21.
2008: David Meyre; Morgane Farge; Cécile Lecoeur; Christine Proenca; Emmanuelle Durand; Frédéric Allegaert; Jean Tichet; Michel Marre; Beverley Balkau; Jacques Weill; Jérôme Delplanque; philippe froguel
R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population.
Human molecular genetics 2008;17(12):1798-802.
2008: Emmanuelle Durand; Cécile Lecoeur; Jérôme Delplanque; Michael Benzinou; Franck Degraeve; Philippe Boutin; Michel Marre; Beverley Balkau; Guillaume Charpentier; philippe froguel; David Meyre
Evaluating the association of FAAH common gene variation with childhood, adult severe obesity and type 2 diabetes in the French population.
Obesity facts 2008;1(6):305-9.
2007: Maya Ghoussaini; Vincent Vatin; Cécile Lecoeur; Victor Abkevich; Adib Younus; Chantal Samson; Christophe Wachter; Barbara Heude; Maïthé Tauber; Patrick Tounian; Serge Hercberg; Jacques Weill; Claire Levy-Marchal; Catherine Le Stunff; Pierre Bougnères; philippe froguel; David Meyre
Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.
The Journal of clinical endocrinology and metabolism 2007;92(11):4403-9.
2007: Christian Dina; David Meyre; Sophie Gallina; Emmanuelle Durand; Antje Körner; Peter Jacobson; Lena Carlsson; Wieland Kiess; Vincent Vatin; Cécile Lecoeur; Jérôme Delplanque; Emmanuel Vaillant; François Pattou; Juan Ruiz; Jacques Weill; Claire Levy-Marchal; Fritz F Horber; Natascha Potoczna; Serge Hercberg; Catherine Le Stunff; Pierre Bougnères; Peter Kovacs; Michel Marre; Beverley Balkau; Stéphane Cauchi; Jean-Claude Chèvre; philippe froguel
Variation in FTO contributes to childhood obesity and severe adult obesity.
Nature genetics 2007;39(6):724-6.
2007: Maria Gueorguiev; Steven Wiltshire; Edwin A Garcia; Charles A Mein; Cécile Lecoeur; Brigitte Kristen; Rebecca Allotey; Andrew T Hattersley; Mark Walker; Stephen O'Rahilly; philippe froguel; Ashley B Grossman; Mark I McCarthy; Graham A Hitman; Marta Korbonits
Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2007;92(6):2201-4.
2007: Nabila Bouatia-Naji; Vincent Vatin; Cécile Lecoeur; Barbara Heude; Christine Proença; Jacques Veslot; Béatrice Jouret; Jean Tichet; Guillaume Charpentier; Michel Marre; Beverley Balkau; philippe froguel; David Meyre
Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.
BMC medical genetics 2007;8():44.
2007: Stéphane Cauchi; David Meyre; Hélène Choquet; Samia Deghmoun; Emmanuelle Durand; Stefan Gaget; Cécile Lecoeur; philippe froguel; Claire Levy-Marchal
TCF7L2 rs7903146 variant does not associate with smallness for gestational age in the French population.
BMC medical genetics 2007;8():37.
2006: Claire Cheyssac; Cécile Lecoeur; Aurélie Dechaume; Amina Bibi; Guillaume Charpentier; Beverley Balkau; Michel Marre; philippe froguel; Fernando Gibson; Martine Vaxillaire
Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population.
BMC medical genetics 2006;7():44.
2005: Laszlo Tanko; Afshan Siddiq; Cécile Lecoeur; Philip J Larsen; Claus Christiansen; Andrew J Walley; philippe froguel
ACDC/adiponectin and PPAR-gamma gene polymorphisms: implications for features of obesity.
Obesity research 2005;13(12):2113-21.
2005: Christopher G Bell; David Meyre; Chantal Samson; Cliona Boyle; Cécile Lecoeur; Maïte Tauber; Béatrice Jouret; Delphine Jaquet; Claire Levy-Marchal; Marie-Aline Charles; Jacques Weill; Fernando Gibson; Charles A Mein; philippe froguel; Andrew J Walley
Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity.
Diabetes 2005;54(10):3049-55.
2005: David Meyre; Nabila Bouatia-Naji; Agnès Tounian; Chantal Samson; Cécile Lecoeur; Vincent Vatin; Maya Ghoussaini; Christophe Wachter; Serge Hercberg; Guillaume Charpentier; Wolfgang Patsch; François Pattou; Marie-Aline Charles; Patrick Tounian; Karine Clément; Béatrice Jouret; Jacques Weill; Betty A Maddux; Ira D Goldfine; Andrew J Walley; Philippe Boutin; Christian Dina; philippe froguel
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
Nature genetics 2005;37(8):863-7.
2004: Christopher G Bell; Michael Benzinou; Afshan Siddiq; Cécile Lecoeur; Christian Dina; Arnaud Lemainque; Karine Clément; Arnaud Basdevant; Bernard Guy-Grand; Charles A Mein; David Meyre; philippe froguel
Genome-wide linkage analysis for severe obesity in french caucasians finds significant susceptibility locus on chromosome 19q.
Diabetes 2004;53(7):1857-65.
2004: David Meyre; Cécile Lecoeur; Jérôme Delplanque; Stephan Francke; Vincent Vatin; Emmanuelle Durand; Jacques Weill; Christian Dina; philippe froguel
A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.
Diabetes 2004;53(3):803-11.
2003: Timothy M Frayling; Cecilia M Lindgren; Jean Claude Chevre; Stephan Menzel; Marie Wishart; Yamina Benmezroua; Alison Brown; Julie C Evans; Pamidghantam Subba Rao; Christian Dina; Cécile Lecoeur; Timo Kanninen; Peter Almgren; Michael P Bulman; Youxiang Wang; James Mills; Rosemarie Wright-Pascoe; Melanie M Mahtani; Francesco Prisco; Angels Costa; Ignacio Cognet; Torben Hansen; Oluf Pedersen; Sian Ellard; Tiinamaija Tuomi; Leif C Groop; philippe froguel; Andrew T Hattersley; Martine Vaxillaire
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
Diabetes 2003;52(3):872-81.
2002: Marta Korbonits; Maria Gueorguiev; Eithne O'Grady; Cécile Lecoeur; Daniel C Swan; Charles A Mein; Jacques Weill; Ashley B Grossman; philippe froguel
A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children.
The Journal of clinical endocrinology and metabolism 2002;87(8):4005-8.
2002: Yasumichi Mori; Shuichi Otabe; Christian Dina; Kazuki Yasuda; Céline Populaire; Cécile Lecoeur; Vincent Vatin; Emmanuelle Durand; Kazuo Hara; Terumasa Okada; Kazuyuki Tobe; Philippe Boutin; Takashi Kadowaki; philippe froguel
Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.
Diabetes 2002;51(4):1247-55.
2001: Stephan Francke; MD Manraj; Corinne Lacquemant; Cécile Lecoeur; frederic lepretre; Philippe Passa; A Hebe; Laetitia Corset; S L Yan; Saida Lahmidi; S Jankee; T K Gunness; U S Ramjuttun; V Balgobin; Christian Dina; philippe froguel
A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.
Human molecular genetics 2001;10(24):2751-65.
2001: Sophie Dupont; El Habib Hani; Corentin Cras-Méneur; F De Matos; Stéphane Lobbens; Cécile Lecoeur; Martine Vaxillaire; Raphael Scharfmann; philippe froguel
No evidence for linkage or for diabetes-associated mutations in the activin type 2B receptor gene (ACVR2B) in French patients with mature-onset diabetes of the young or type 2 diabetes.
Diabetes 2001;50(5):1219-21.
2000: Nathalie Vionnet; El Habib Hani; Sophie Dupont; Sophie Gallina; Stephan Francke; S Dotte; F De Matos; Emmanuelle Durand; frederic lepretre; Cécile Lecoeur; P Gallina; L Zekiri; Christian Dina; philippe froguel
Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.
American journal of human genetics 2000;67(6):1470-80.