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Juliette Lecomte

Research Profile

Chemicals & Drugs

Phenomena

Magnetic Resonance Spectroscopy

Procedures

Nuclear Magnetic Resonance, Biomolecular

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Genes & Molecular Sequences

Amino Acid Sequences

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Protein Denaturation

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Thermodynamics

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Publications

TOP 3
Matthew P Pond; Matthew R Preimesberger; Selena L Rice; Belinda B Wenke; Juliette T J Lecomte
3-Fluorotyrosine as a complementary probe of hemoglobin structure and dynamics: a (19)F-NMR study of Synechococcus sp. PCC 7002 GlbN.
Matthew P Pond; Ananya Majumdar; Juliette T J Lecomte
Influence of heme post-translational modification and distal ligation on the backbone dynamics of a monomeric hemoglobin.
Matthew R Preimesberger; Ananya Majumdar; Matthew P Pond; Juliette T J Lecomte
Electron self-exchange and self-amplified posttranslational modification in the hemoglobins from Synechocystis sp. PCC 6803 and Synechococcus sp. PCC 7002.

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2012: Matthew P Pond; Matthew R Preimesberger; Selena L Rice; Belinda B Wenke; Juliette T J Lecomte
3-Fluorotyrosine as a complementary probe of hemoglobin structure and dynamics: a (19)F-NMR study of Synechococcus sp. PCC 7002 GlbN.
Chemistry & biodiversity 2012;9(9):1703-17.
2012: Matthew P Pond; Ananya Majumdar; Juliette T J Lecomte
Influence of heme post-translational modification and distal ligation on the backbone dynamics of a monomeric hemoglobin.
Biochemistry 2012;51(29):5733-47.
2012: Matthew R Preimesberger; Ananya Majumdar; Matthew P Pond; Juliette T J Lecomte
Electron self-exchange and self-amplified posttranslational modification in the hemoglobins from Synechocystis sp. PCC 6803 and Synechococcus sp. PCC 7002.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2012;17(4):599-609.
2011: Henry J Nothnagel; Matthew R Preimesberger; Matthew P Pond; Benjamin Y Winer; Emily M Adney; Juliette T J Lecomte
Chemical reactivity of Synechococcus sp. PCC 7002 and Synechocystis sp. PCC 6803 hemoglobins: covalent heme attachment and bishistidine coordination.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2011;16(4):539-52.
2011: Henry J Nothnagel; Benjamin Y Winer; David A Vuletich; Matthew P Pond; Juliette T J Lecomte
Structural properties of 2/2 hemoglobins: the group III protein from Helicobacter hepaticus.
IUBMB life 2011;63(3):197-205.
2010: Nancy L Scott; Yu Xu; Gaozhong Shen; David A Vuletich; Christopher J Falzone; Zhongkui Li; Marcus Ludwig; Matthew P Pond; Matthew R Preimesberger; Donald A Bryant; Juliette T J Lecomte
Functional and structural characterization of the 2/2 hemoglobin from Synechococcus sp. PCC 7002.
Biochemistry 2010;49(33):7000-11.
2009: Matthew P Pond; David A Vuletich; Christopher J Falzone; Ananya Majumdar; Juliette T J Lecomte
(1)H, (15)N, and (13)C resonance assignments of the 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 in the ferric bis-histidine state.
Biomolecular NMR assignments 2009;3(2):211-4.
2009: Henry J Nothnagel; Nicole Love; Juliette T J Lecomte
The role of the heme distal ligand in the post-translational modification of Synechocystis hemoglobin.
Journal of inorganic biochemistry 2009;103(1):107-16.
2008: Joel Graham; Juliette T J Lecomte; Donald A Bryant
Synechoxanthin, an aromatic C40 xanthophyll that is a major carotenoid in the cyanobacterium Synechococcus sp. PCC 7002.
Journal of natural products 2008;71(9):1647-50.
2008: Juliette T J Lecomte; Kunal Mukhopadhyay; Matthew P Pond
Structural and thermodynamic encoding in the sequence of rat microsomal cytochrome b(5).
Biopolymers 2008;89(5):428-42.
2008: Ronald B Davis; Juliette T J Lecomte
Structural propensities in the heme binding region of apocytochrome b5. II. Heme conjugates.
Biopolymers 2008;90(4):556-66.
2008: Ronald B Davis; Juliette T J Lecomte
Structural propensities in the heme binding region of apocytochrome b5. I. Free peptides.
Biopolymers 2008;90(4):544-55.
2007: Daniel A Landfried; David A Vuletich; Matthew P Pond; Juliette T J Lecomte
Structural and thermodynamic consequences of b heme binding for monomeric apoglobins and other apoproteins.
Gene 2007;398(1-2):12-28.
2007: Jane A Knappenberger; Juliette T J Lecomte
Loop anchor modification causes the population of an alternative native state in an SH3-like domain.
Protein science : a publication of the Protein Society 2007;16(5):863-79.
2006: David A Vuletich; Christopher J Falzone; Juliette T J Lecomte
Structural and dynamic repercussions of heme binding and heme-protein cross-linking in Synechococcus sp. PCC 7002 hemoglobin.
Biochemistry 2006;45(47):14075-84.
2006: Jane A Knappenberger; Syna A Kuriakose; B Christie Vu; Henry J Nothnagel; David A Vuletich; Juliette T J Lecomte
Proximal influences in two-on-two globins: effect of the Ala69Ser replacement on Synechocystis sp. PCC 6803 hemoglobin.
Biochemistry 2006;45(38):11401-13.
2006: Julie E Bryant; Juliette T J Lecomte; Andrew L Lee; Gregory B Young; Gary J Pielak
Cytosol has a small effect on protein backbone dynamics.
Biochemistry 2006;45(33):10085-91.
2006: Ronald B Davis; Juliette T J Lecomte
A dynamic N-capping motif in cytochrome b5: evidence for a pH-controlled conformational switch.
Proteins 2006;63(2):336-48.
2006: David A Vuletich; Juliette T J Lecomte
A phylogenetic and structural analysis of truncated hemoglobins.
Journal of molecular evolution 2006;62(2):196-210.
2005: Juliette T J Lecomte; B Christie Vu; Christopher J Falzone
Structural and dynamic properties of Synechocystis sp. PCC 6803 Hb revealed by reconstitution with Zn-protoporphyrin IX.
Journal of inorganic biochemistry 2005;99(8):1585-92.
2005: Julie E Bryant; Juliette T J Lecomte; Andrew L Lee; Gregory B Young; Gary J Pielak
Protein dynamics in living cells.
Biochemistry 2005;44(26):9275-9.
2005: Juliette T J Lecomte; David A Vuletich; Arthur M Lesk
Structural divergence and distant relationships in proteins: evolution of the globins.
Current opinion in structural biology 2005;15(3):290-301.
2005: Philip C Bevilacqua; Trevor S Brown; Durga M Chadalavada; Juliette T J Lecomte; Ellen M Moody; Shu-ichi Nakano
Linkage between proton binding and folding in RNA: implications for RNA catalysis.
Biochemical Society transactions 2005;33(Pt 3):466-70.
2005: Ellen M Moody; Juliette T J Lecomte; Philip C Bevilacqua
Linkage between proton binding and folding in RNA: a thermodynamic framework and its experimental application for investigating pKa shifting.
RNA (New York, N.Y.) 2005;11(2):157-72.
2004: Jane A Knappenberger; Christina M Kraemer-Pecore; Juliette T J Lecomte
Insertion of the cytochrome b5 heme-binding loop into an SH3 domain. Effects on structure and stability, and clues about the cytochrome's architecture.
Protein science : a publication of the Protein Society 2004;13(11):2899-908.
2004: B Christie Vu; Henry J Nothnagel; David A Vuletich; Christopher J Falzone; Juliette T J Lecomte
Cyanide binding to hexacoordinate cyanobacterial hemoglobins: hydrogen-bonding network and heme pocket rearrangement in ferric H117A Synechocystis hemoglobin.
Biochemistry 2004;43(39):12622-33.
2004: Kunal Mukhopadhyay; Juliette T J Lecomte
A relationship between heme binding and protein stability in cytochrome b5.
Biochemistry 2004;43(38):12227-36.
2004: B Christie Vu; David A Vuletich; Syna A Kuriakose; Christopher J Falzone; Juliette T J Lecomte
Characterization of the heme-histidine cross-link in cyanobacterial hemoglobins from Synechocystis sp. PCC 6803 and Synechococcus sp. PCC 7002.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(2):183-94.
2004: Juliette T J Lecomte; David A Vuletich; B Christie Vu; Syna A Kuriakose; Nancy L Scott; Christopher J Falzone
Structural properties of cyanobacterial hemoglobins: the unusual heme-protein cross-link of Synechocystis sp. PCC 6803 Hb and Synechococcus sp. PCC 7002 Hb.
Micron (Oxford, England : 1993) 2004;35(1-2):71-2.
2003: Christina M Kraemer-Pecore; Juliette T J Lecomte; John Desjarlais
A de novo redesign of the WW domain.
Protein science : a publication of the Protein Society 2003;12(10):2194-205.
2002: Christopher J Falzone; B Christie Vu; Nancy L Scott; Juliette T J Lecomte
The solution structure of the recombinant hemoglobin from the cyanobacterium Synechocystis sp. PCC 6803 in its hemichrome state.
Journal of molecular biology 2002;324(5):1015-29.
2002: B Christie Vu; A Daniel Jones; Juliette T J Lecomte
Novel histidine-heme covalent linkage in a hemoglobin.
Journal of the American Chemical Society 2002;124(29):8544-5.
2002: Nancy L Scott; Christopher J Falzone; David A Vuletich; Jindong Zhao; Donald A Bryant; Juliette T J Lecomte
Truncated hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002: evidence for hexacoordination and covalent adduct formation in the ferric recombinant protein.
Biochemistry 2002;41(22):6902-10.
2002: Christopher J Falzone; Juliette T J Lecomte
Assignment of the 1H, 13C, and 15N signals of Synechocystis sp. PCC 6803 methemoglobin.
Journal of biomolecular NMR 2002;23(1):71-2.
2002: Kelly K Lee; Carolyn Fitch; Juliette T J Lecomte; Bertrand García-Moreno E
Electrostatic effects in highly charged proteins: salt sensitivity of pKa values of histidines in staphylococcal nuclease.
Biochemistry 2002;41(17):5656-67.
2001: Juliette T J Lecomte; Nancy L Scott; B Christie Vu; Christopher J Falzone
Binding of ferric heme by the recombinant globin from the cyanobacterium Synechocystis sp. PCC 6803.
Biochemistry 2001;40(21):6541-52.
2001: Christopher J Falzone; Y Wang; B Christie Vu; Nancy L Scott; S Bhattacharya; Juliette T J Lecomte
Structural and dynamic perturbations induced by heme binding in cytochrome b5.
Biochemistry 2001;40(15):4879-91.
2000: Y H Kao; Carolyn Fitch; S Bhattacharya; C J Sarkisian; Juliette T J Lecomte; Bertrand García-Moreno E
Salt effects on ionization equilibria of histidines in myoglobin.
Biophysical journal 2000;79(3):1637-54.
2000: Nancy L Scott; Juliette T J Lecomte
Cloning, expression, purification, and preliminary characterization of a putative hemoglobin from the cyanobacterium Synechocystis sp. PCC 6803.
Protein science : a publication of the Protein Society 2000;9(3):587-97.
1999: K L Mayer; Gaozhong Shen; Donald A Bryant; Juliette T J Lecomte; Christopher J Falzone
The solution structure of photosystem I accessory protein E from the cyanobacterium Nostoc sp. strain PCC 8009.
Biochemistry 1999;38(41):13736-46.
1999: Juliette T J Lecomte; SF Sukits; S Bhattacharya; Christopher J Falzone
Conformational properties of native sperm whale apomyoglobin in solution.
Protein science : a publication of the Protein Society 1999;8(7):1484-91.
1999: Juliette T J Lecomte; Christopher J Falzone
Where U and I meet.
Nature structural biology 1999;6(7):605-8.
1999: S Bhattacharya; Christopher J Falzone; Juliette T J Lecomte
Backbone dynamics of apocytochrome b5 in its native, partially folded state.
Biochemistry 1999;38(8):2577-89.
1998: A J Constans; M R Mayer; SF Sukits; Juliette T J Lecomte
A test of the relationship between sequence and structure in proteins: excision of the heme binding site in apocytochrome b5.
Protein science : a publication of the Protein Society 1998;7(9):1983-93.
1997: S Bhattacharya; Juliette T J Lecomte
Temperature dependence of histidine ionization constants in myoglobin.
Biophysical journal 1997;73(6):3241-56.
1997: S Bhattacharya; SF Sukits; K L MacLaughlin; Juliette T J Lecomte
The tautomeric state of histidines in myoglobin.
Biophysical journal 1997;73(6):3230-40.
1996: Juliette T J Lecomte; Y H Kao; Melanie Cocco
The native state of apomyoglobin described by proton NMR spectroscopy: the A-B-G-H interface of wild-type sperm whale apomyoglobin.
Proteins 1996;25(3):267-85.
1996: Christopher J Falzone; M R Mayer; E L Whiteman; C D Moore; Juliette T J Lecomte
Design challenges for hemoproteins: the solution structure of apocytochrome b5.
Biochemistry 1996;35(21):6519-26.
1994: Christopher J Falzone; Y H Kao; J Zhao; Donald A Bryant; Juliette T J Lecomte
Three-dimensional solution structure of PsaE from the cyanobacterium Synechococcus sp. strain PCC 7002, a photosystem I protein that shows structural homology with SH3 domains.
Biochemistry 1994;33(20):6052-62.
1994: Christopher J Falzone; Y H Kao; J Zhao; K L MacLaughlin; Donald A Bryant; Juliette T J Lecomte
1H and 15N NMR assignments of PsaE, a photosystem I subunit from the cyanobacterium Synechococcus sp. strain PCC 7002.
Biochemistry 1994;33(20):6043-51.
1994: Melanie Cocco; Juliette T J Lecomte
The native state of apomyoglobin described by proton NMR spectroscopy: interaction with the paramagnetic probe HyTEMPO and the fluorescent dye ANS.
Protein science : a publication of the Protein Society 1994;3(2):267-81.
1993: C D Moore; Juliette T J Lecomte
Characterization of an independent structural unit in apocytochrome b5.
Biochemistry 1993;32(1):199-207.
1993: Juliette T J Lecomte; C R Matthews
Unraveling the mechanism of protein folding: new tricks for an old problem.
Protein engineering 1993;6(1):1-10.
1992: Melanie Cocco; Y H Kao; A T Phillips; Juliette T J Lecomte
Structural comparison of apomyoglobin and metaquomyoglobin: pH titration of histidines by NMR spectroscopy.
Biochemistry 1992;31(28):6481-91.
1991: C D Moore; O N al-Misky; Juliette T J Lecomte
Similarities in structure between holocytochrome b5 and apocytochrome b5: NMR studies of the histidine residues.
Biochemistry 1991;30(34):8357-65.
1990: Melanie Cocco; Juliette T J Lecomte
Characterization of hydrophobic cores in apomyoglobin: a proton NMR spectroscopy study.
Biochemistry 1990;29(50):11067-72.
1990: Juliette T J Lecomte; Melanie Cocco
Structural features of the protoporphyrin-apomyoglobin complex: a proton NMR spectroscopy study.
Biochemistry 1990;29(50):11057-67.
1990: C D Moore; Juliette T J Lecomte
Structural properties of apocytochrome b5: presence of a stable native core.
Biochemistry 1990;29(8):1984-9.