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Jeffrey Ledbetter

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Xizhang Sun; Lena Tanaka; Thomas H Teal; Alice Wiedeman; Nalini Agrawal; Charles E Alpers; Silvia Bolland; Matthew B Buechler; Jessica A Hamerman; Kelly L Hudkins; Jeffrey A Ledbetter; Denny Liggitt; Keith B Elkon
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
Jay W Chaplin; Edward A Clark; Shinji Kasahara; Jeffrey A Ledbetter
Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway.
Edward A Clark; Jeffrey A Ledbetter
How does B cell depletion therapy work, and how can it be improved?

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All Publications

2013: Xizhang Sun; Lena Tanaka; Thomas H Teal; Alice Wiedeman; Nalini Agrawal; Charles E Alpers; Silvia Bolland; Matthew B Buechler; Jessica A Hamerman; Kelly L Hudkins; Jeffrey A Ledbetter; Denny Liggitt; Keith B Elkon
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2536-43.
2011: Jay W Chaplin; Edward A Clark; Shinji Kasahara; Jeffrey A Ledbetter
Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(8):4199-209.
2005: Edward A Clark; Jeffrey A Ledbetter
How does B cell depletion therapy work, and how can it be improved?
Annals of the rheumatic diseases 2005;64 Suppl 4():iv77-80.
2003: Ingegerd Hellström; John Raycraft; Martha Hayden-Ledbetter; Jeffrey A Ledbetter; Michèl Schummer; Martin McIntosh; Charles W Drescher; Nicole Urban; Karl Erik Hellström
The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.
Cancer research 2003;63(13):3695-700.
2002: Che-Leung Law; Martha Hayden-Ledbetter; Sonya Buckwalter; Lisa McNeill; Hieu Nguyen; Phil Habecker; Barbara A Thorne; Raj Dua; Jeffrey A Ledbetter
Expression and characterization of recombinant soluble human CD3 molecules: presentation of antigenic epitopes defined on the native TCR-CD3 complex.
International immunology 2002;14(4):389-400.
2002: Zhengmao Ye; Ingegerd Hellström; Martha Hayden-Ledbetter; Amber Dahlin; Jeffrey A Ledbetter; Karl Erik Hellström
Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB.
Nature medicine 2002;8(4):343-8.
2002: Nathalie Scholler; Martha Hayden-Ledbetter; Amber Dahlin; Ingegerd Hellström; Karl Erik Hellström; Jeffrey A Ledbetter
Cutting edge: CD83 regulates the development of cellular immunity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2599-602.
2001: G Richter; Martha Hayden-Ledbetter; M Irgang; Jeffrey A Ledbetter; J Westermann; Ida J Körner; K Daemen; Edward A Clark; Alexandra Aicher; Antonio Pezzutto
Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34(+) progenitor cells during differentiation into antigen presenting cells.
The Journal of biological chemistry 2001;276(49):45686-93.
2001: Sporici Romeo; Richard L Beswick; C von Allmen; Catherine A Rumbley; Martha Hayden-Ledbetter; Jeffrey A Ledbetter; Peter J Perrin
ICOS ligand costimulation is required for T-cell encephalitogenicity.
Clinical immunology (Orlando, Fla.) 2001;100(3):277-88.
2001: Ingegerd Hellstrom; Jeffrey A Ledbetter; Nathalie Scholler; Yi Yang; Z Ye; G Goodman; Janice Pullman; Martha Hayden-Ledbetter; Karl Erik Hellstrom
CD3-mediated activation of tumor-reactive lymphocytes from patients with advanced cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(12):6783-8.
2001: Nathalie Scholler; Martha Hayden-Ledbetter; Karl Erik Hellström; Ingegerd Hellström; Jeffrey A Ledbetter
CD83 is an I-type lectin adhesion receptor that binds monocytes and a subset of activated CD8+ T cells [corrected].
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):3865-72.
2000: SM Fujihara; Jeff Cleaveland; LS Grosmaire; KK Berry; K A Kennedy; J J Blake; JK Loy; BM Rankin; Jeffrey A Ledbetter; Steven G Nadler
A D-amino acid peptide inhibitor of NF-kappa B nuclear localization is efficacious in models of inflammatory disease.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):1004-12.
2000: Alexandra Aicher; Martha Hayden-Ledbetter; W A Brady; Antonio Pezzutto; G Richter; Dario M Magaletti; S Buckwalter; Jeffrey A Ledbetter; Edward A Clark
Characterization of human inducible costimulator ligand expression and function.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4689-96.
2000: D Shan; Jeffrey A Ledbetter; Oliver W Press
Signaling events involved in anti-CD20-induced apoptosis of malignant human B cells.
Cancer immunology, immunotherapy : CII 2000;48(12):673-83.
1999: L Zhao; S K Rai; LS Grosmaire; Jeffrey A Ledbetter; H P Fell
Construction, expression, and characterization of anticarcinoma sFv fused to IL-2 or GM-CSF.
Journal of hematotherapy & stem cell research 1999;8(4):393-9.
1999: D Shan; Oliver W Press; T T Tsu; MS Hayden; Jeffrey A Ledbetter
Characterization of scFv-Ig constructs generated from the anti-CD20 mAb 1F5 using linker peptides of varying lengths.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6589-95.
1998: R J Connelly; MS Hayden; JK Scholler; T T Tsu; Bo Dupont; Jeffrey A Ledbetter; Steven B Kanner
Mitogenic properties of a bispecific single-chain Fv-Ig fusion generated from CD2-specific mAb to distinct epitopes.
International immunology 1998;10(12):1863-72.
1998: Geoffrey M Gersuk; C Beckham; Michael R Loken; Peter Kiener; J E Anderson; A Farrand; A B Troutt; Jeffrey A Ledbetter; H Joachim Deeg
A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome.
British journal of haematology 1998;103(1):176-88.
1998: D Shan; Jeffrey A Ledbetter; Oliver W Press
Apoptosis of malignant human B cells by ligation of CD20 with monoclonal antibodies.
Blood 1998;91(5):1644-52.
1997: J W Lee; Geoffrey M Gersuk; Peter Kiener; C Beckham; Jeffrey A Ledbetter; H Joachim Deeg
HLA-DR-triggered inhibition of hemopoiesis involves Fas/Fas ligand interactions and is prevented by c-kit ligand.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3211-9.
1997: Peter Kiener; PM Davis; BM Rankin; Seymour J Klebanoff; Jeffrey A Ledbetter; Gary C Starling; W Conrad Liles
Human monocytic cells contain high levels of intracellular Fas ligand: rapid release following cellular activation.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1594-8.
1997: WW Shuford; K Klussman; D D Tritchler; DT Loo; J Chalupny; Anthony W Siadak; T J Brown; John Emswiler; H Raecho; Christian P Larsen; Thomas C Pearson; Jeffrey A Ledbetter; Alejandro Aruffo; Robert S Mittler
4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.
The Journal of experimental medicine 1997;186(1):47-55.
1997: Joseph A Francisco; G J Schreiber; C R Comereski; L E Mezza; G L Warner; T J Davidson; Jeffrey A Ledbetter; Clay B Siegall
In vivo efficacy and toxicity of a single-chain immunotoxin targeted to CD40.
Blood 1997;89(12):4493-500.
1997: I Melero; WW Shuford; S A Newby; Alejandro Aruffo; Jeffrey A Ledbetter; Karl Erik Hellström; Robert S Mittler; L Chen
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors.
Nature medicine 1997;3(6):682-5.
1997: Cecile Krejsa; Steven G Nadler; J M Esselstyn; Terrance J Kavanagh; Jeffrey A Ledbetter; GL Schieven
Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors. Redox independent activation of NF-kappaB.
The Journal of biological chemistry 1997;272(17):11541-9.
1997: Peter Kiener; PM Davis; Gary C Starling; Christopher Mehlin; Seymour J Klebanoff; Jeffrey A Ledbetter; W Conrad Liles
Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages.
The Journal of experimental medicine 1997;185(8):1511-6.
1997: Gary C Starling; Jurgen Bajorath; John Emswiler; Jeffrey A Ledbetter; Alejandro Aruffo; Peter Kiener
Identification of amino acid residues important for ligand binding to Fas.
The Journal of experimental medicine 1997;185(8):1487-92.
1997: MS Hayden; L K Gilliland; Jeffrey A Ledbetter
Antibody engineering.
Current opinion in immunology 1997;9(2):201-12.
1997: Peter Kiener; MN Lioubin; Larry R Rohrschneider; Jeffrey A Ledbetter; Steven G Nadler; M L Diegel
Co-ligation of the antigen and Fc receptors gives rise to the selective modulation of intracellular signaling in B cells. Regulation of the association of phosphatidylinositol 3-kinase and inositol 5'-phosphatase with the antigen receptor complex.
The Journal of biological chemistry 1997;272(6):3838-44.
1997: Jeffrey A Ledbetter; Joseph A Francisco; Clay B Siegall; L K Gilliland; Diane L Hollenbaugh; Alejandro Aruffo; Anthony W Siadak; N Mischel-Petty; LS Grosmaire; M L Gordon; T J Brown; P Moran-Davis; Robert S Mittler; Peter Kiener; Steven G Nadler
Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5.
Critical reviews in immunology 1997;17(5-6):427-35.
1996: N V Sherbina; Peter Linsley; S Myrdal; LS Grosmaire; Jeffrey A Ledbetter; G L Schieven
Intracellular CD22 rapidly moves to the cell surface in a tyrosine kinase-dependent manner following antigen receptor stimulation.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4390-8.
1996: G Winberg; LS Grosmaire; K Klussman; MS Hayden; H P Fell; Jeffrey A Ledbetter; Robert S Mittler
Surface expression of CD28 single chain Fv for costimulation by tumor cells.
Immunological reviews 1996;153():209-23.
1996: MS Hayden; LS Grosmaire; N A Norris; L K Gilliland; G Winberg; D Tritschler; T T Tsu; Peter Linsley; Robert S Mittler; Peter D Senter; H P Fell; Jeffrey A Ledbetter
Costimulation by CD28 sFv expressed on the tumor cell surface or as a soluble bispecific molecule targeted to the L6 carcinoma antigen.
Tissue antigens 1996;48(4 Pt 1):242-54.
1996: Joseph A Francisco; Peter Kiener; P Moran-Davis; Jeffrey A Ledbetter; Clay B Siegall
Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1652-8.
1996: W Conrad Liles; Peter Kiener; Jeffrey A Ledbetter; Alejandro Aruffo; Seymour J Klebanoff
Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.
The Journal of experimental medicine 1996;184(2):429-40.
1996: P M Dubois; D Palmer; Maria L Webb; Jeffrey A Ledbetter; R A Shapiro
Early signal transduction by the receptor to the chemokine monocyte chemotactic protein-1 in a murine T cell hybrid.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1356-61.
1996: L K Gilliland; N A Norris; H Marquardt; T T Tsu; MS Hayden; M G Neubauer; D E Yelton; Robert S Mittler; Jeffrey A Ledbetter
Rapid and reliable cloning of antibody variable regions and generation of recombinant single chain antibody fragments.
Tissue antigens 1996;47(1):1-20.
1995: W Conrad Liles; Jeffrey A Ledbetter; A W Waltersdorph; Seymour J Klebanoff
Cross-linking of CD18 primes human neutrophils for activation of the respiratory burst in response to specific stimuli: implications for adhesion-dependent physiological responses in neutrophils.
Journal of leukocyte biology 1995;58(6):690-7.
1995: D S Hong; C Beckham; Ralf Huss; J W Lee; David M Hockenbery; Jeffrey A Ledbetter; H Joachim Deeg
Major histocompatibility complex class II-mediated inhibition of hematopoiesis in long-term marrow cultures involves apoptosis and is prevented by c-kit ligand.
Blood 1995;86(9):3341-52.
1995: N J Chalupny; Alejandro Aruffo; J M Esselstyn; P Y Chan; J Bajorath; J Blake; L K Gilliland; Jeffrey A Ledbetter; Mark Tepper
Specific binding of Fyn and phosphatidylinositol 3-kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains.
European journal of immunology 1995;25(10):2978-84.
1995: J P Deans; L Kalt; Jeffrey A Ledbetter; G L Schieven; J B Bolen; Pauline Johnson
Association of 75/80-kDa phosphoproteins and the tyrosine kinases Lyn, Fyn, and Lck with the B cell molecule CD20. Evidence against involvement of the cytoplasmic regions of CD20.
The Journal of biological chemistry 1995;270(38):22632-8.
1995: Steven B Kanner; LS Grosmaire; J Blake; G L Schieven; S Masewicz; N Odum; Jeffrey A Ledbetter
ZAP-70 and p72syk are signaling response elements through MHC class II molecules.
Tissue antigens 1995;46(3 ( Pt 1)):145-54.
1995: G L Schieven; Alan F Wahl; S Myrdal; LS Grosmaire; Jeffrey A Ledbetter
Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).
The Journal of biological chemistry 1995;270(35):20824-31.
1995: W Conrad Liles; Jeffrey A Ledbetter; A W Waltersdorph; Seymour J Klebanoff
Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(4):2175-84.
1995: Joseph A Francisco; L K Gilliland; M R Stebbins; N A Norris; Jeffrey A Ledbetter; Clay B Siegall
Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen.
Cancer research 1995;55(14):3099-104.
1995: A Grossmann; Peter S Rabinovitch; Terrance J Kavanagh; J C Jinneman; L K Gilliland; Jeffrey A Ledbetter; Steven B Kanner
Activation of murine T-cells via phospholipase-C gamma 1-associated protein tyrosine phosphorylation is reduced with aging.
The journals of gerontology. Series A, Biological sciences and medical sciences 1995;50(4):B205-12.
1995: Peter Linsley; Jeffrey A Ledbetter; Robert Peach; J Bajorath
CD28/CTLA-4 receptor structure, binding stoichiometry and aggregation during T-cell activation.
Research in immunology 1995;146(3):130-40.
1994: G S Chatta; A G Spies; S Chang; Gregory J Mize; Peter Linsley; Jeffrey A Ledbetter; David R Morris
Differential regulation of proto-oncogenes c-jun and c-fos in T lymphocytes activated through CD28.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(12):5393-401.
1994: Peter Linsley; J L Greene; W Brady; J Bajorath; Jeffrey A Ledbetter; Robert Peach
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors.
Immunity 1994;1(9):793-801.
1994: Jeffrey A Ledbetter; LS Grosmaire; Diane L Hollenbaugh; Alejandro Aruffo; Steven G Nadler
Agonistic and antagonistic properties of CD40 mAb G28-5 are dependent on binding valency.
Circulatory shock 1994;44(2):67-72.
1994: M T Dietsch; P Y Chan; Steven B Kanner; L K Gilliland; Jeffrey A Ledbetter; Peter Linsley; Alejandro Aruffo
Coengagement of CD2 with LFA-1 or VLA-4 by bispecific ligand fusion proteins primes T cells to respond more effectively to T cell receptor-dependent signals.
Journal of leukocyte biology 1994;56(4):444-52.
1994: G L Schieven; Robert S Mittler; Steven G Nadler; J M Kirihara; J B Bolen; Steven B Kanner; Jeffrey A Ledbetter
ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.
The Journal of biological chemistry 1994;269(32):20718-26.
1994: J P Deans; Jeffrey A Ledbetter; Linda M Pilarski
Differential modulation of human multinegative (CD3-4-8-) thymocyte proliferation by monoclonal antibodies to CD45RA or to CD45.
Immunology and cell biology 1994;72(4):292-9.
1994: Diane L Hollenbaugh; L H Wu; H D Ochs; Shigeaki Nonoyama; LS Grosmaire; Jeffrey A Ledbetter; R J Noelle; H Hill; Alejandro Aruffo
The random inactivation of the X chromosome carrying the defective gene responsible for X-linked hyper IgM syndrome (X-HIM) in female carriers of HIGM1.
The Journal of clinical investigation 1994;94(2):616-22.
1994: Diane L Hollenbaugh; H D Ochs; R J Noelle; Jeffrey A Ledbetter; Alejandro Aruffo
The role of CD40 and its ligand in the regulation of the immune response.
Immunological reviews 1994;138():23-37.
1994: Nitin Damle; K Klussman; G Leytze; S Myrdal; Alejandro Aruffo; Jeffrey A Ledbetter; Peter Linsley
Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2686-97.
1994: Edward A Clark; Jeffrey A Ledbetter
How B and T cells talk to each other.
Nature 1994;367(6462):425-8.
1994: M Farrington; LS Grosmaire; Shigeaki Nonoyama; S H Fischer; Diane L Hollenbaugh; Jeffrey A Ledbetter; R J Noelle; Alejandro Aruffo; Hans D Ochs
CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):1099-103.
1994: M Parsons; Jeffrey A Ledbetter; G L Schieven; A E Nel; S B Kanner
Developmental regulation of pp44/46, tyrosine-phosphorylated proteins associated with tyrosine/serine kinase activity in Trypanosoma brucei.
Molecular and biochemical parasitology 1994;63(1):69-78.
1994: MS Hayden; Peter Linsley; M A Gayle; J Bajorath; W A Brady; N A Norris; H P Fell; Jeffrey A Ledbetter; L K Gilliland
Single-chain mono- and bispecific antibody derivatives with novel biological properties and antitumour activity from a COS cell transient expression system.
Therapeutic immunology 1994;1(1):3-15.
1993: Peter Kiener; B M Rankin; A L Burkhardt; G L Schieven; L K Gilliland; R B Rowley; J B Bolen; Jeffrey A Ledbetter
Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase.
The Journal of biological chemistry 1993;268(32):24442-8.
1993: J P Deans; G L Schieven; Geraldine L Shu; M A Valentine; L A Gilliland; Alejandro Aruffo; Edward A Clark; Jeffrey A Ledbetter
Association of tyrosine and serine kinases with the B cell surface antigen CD20. Induction via CD20 of tyrosine phosphorylation and activation of phospholipase C-gamma 1 and PLC phospholipase C-gamma 2.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(9):4494-504.
1993: G L Schieven; Jeffrey A Ledbetter
Ultraviolet radiation induces differential calcium signals in human peripheral blood lymphocyte subsets.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(3):221-5.
1993: Nitin Damle; K Klussman; G Leytze; Alejandro Aruffo; Peter Linsley; Jeffrey A Ledbetter
Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(5):2368-79.
1993: Shigeaki Nonoyama; Diane L Hollenbaugh; Alejandro Aruffo; Jeffrey A Ledbetter; Hans D Ochs
B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells.
The Journal of experimental medicine 1993;178(3):1097-102.
1993: G L Schieven; J M Kirihara; DE Myers; Jeffrey A Ledbetter; fatih uckun
Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes.
Blood 1993;82(4):1212-20.
1993: G L Schieven; J M Kirihara; D L Burg; Robert L Geahlen; Jeffrey A Ledbetter
p72syk tyrosine kinase is activated by oxidizing conditions that induce lymphocyte tyrosine phosphorylation and Ca2+ signals.
The Journal of biological chemistry 1993;268(22):16688-92.
1993: Steven B Kanner; LS Grosmaire; Jeffrey A Ledbetter; Nitin Damle
Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7099-103.
1993: Nitin Damle; G Leytze; K Klussman; Jeffrey A Ledbetter
Activation with superantigens induces programmed death in antigen-primed CD4+ class II+ major histocompatibility complex T lymphocytes via a CD11a/CD18-dependent mechanism.
European journal of immunology 1993;23(7):1513-22.
1993: N J Chalupny; Steven B Kanner; G L Schieven; S F Wee; L K Gilliland; Alejandro Aruffo; Jeffrey A Ledbetter
Tyrosine phosphorylation of CD19 in pre-B and mature B cells.
The EMBO journal 1993;12(7):2691-6.
1993: M T Dietsch; V F Smith; W L Cosand; Nitin Damle; Jeffrey A Ledbetter; Peter Linsley; Alejandro Aruffo
Bispecific receptor globulins, novel tools for the study of cellular interactions. Preparation and characterization of an E-selectin/P-selectin bispecific receptor globulin.
Journal of immunological methods 1993;162(1):123-32.
1993: Jeffrey A Ledbetter; J P Deans; Alejandro Aruffo; LS Grosmaire; Steven B Kanner; J B Bolen; G L Schieven
CD4, CD8 and the role of CD45 in T-cell activation.
Current opinion in immunology 1993;5(3):334-40.
1993: G L Schieven; J M Kirihara; L K Gilliland; fatih uckun; Jeffrey A Ledbetter
Ultraviolet radiation rapidly induces tyrosine phosphorylation and calcium signaling in lymphocytes.
Molecular biology of the cell 1993;4(5):523-30.
1993: P A Moran; M L Diegel; J C Sias; Jeffrey A Ledbetter; J M Zarling
Regulation of HIV production by blood mononuclear cells from HIV-infected donors: I. Lack of correlation between HIV-1 production and T cell activation.
AIDS research and human retroviruses 1993;9(5):455-64.
1993: M L Diegel; P A Moran; L K Gilliland; N K Damle; MS Hayden; J M Zarling; Jeffrey A Ledbetter
Regulation of HIV production by blood mononuclear cells from HIV-infected donors: II. HIV-1 production depends on T cell-monocyte interaction.
AIDS research and human retroviruses 1993;9(5):465-73.
1993: corinne leprince; Kevin E Draves; R L Geahlen; Jeffrey A Ledbetter; Edward A Clark
CD22 associates with the human surface IgM-B-cell antigen receptor complex.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3236-40.
1993: Nitin Damle; K Klussman; G Leytze; H D Ochs; Alejandro Aruffo; Peter Linsley; Jeffrey A Ledbetter
Costimulation via vascular cell adhesion molecule-1 induces in T cells increased responsiveness to the CD28 counter-receptor B7.
Cellular immunology 1993;148(1):144-56.
1993: Peter Linsley; J Bradshaw; M Urnes; LS Grosmaire; Jeffrey A Ledbetter
CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3161-9.
1993: Terrance J Kavanagh; A Grossmann; J C Jinneman; Steven B Kanner; Collin C White; David Eaton; Jeffrey A Ledbetter; Peter S Rabinovitch
The effect of 1-chloro-2,4-dinitrobenzene exposure on antigen receptor (CD3)-stimulated transmembrane signal transduction in purified subsets of human peripheral blood lymphocytes.
Toxicology and applied pharmacology 1993;119(1):91-9.
1993: S Masewicz; Jeffrey A Ledbetter; P Martin; Eric Mickelson; John A Hansen; N Odum
Inhibition of allostimulated HLA-DQ and DP-specific T cells by staphylococcal enterotoxin A.
Human immunology 1993;36(3):142-8.
1993: fatih uckun; G L Schieven; L M Tuel-Ahlgren; Ilker Dibirdik; DE Myers; Jeffrey A Ledbetter; Chang W Song
Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):252-6.
1993: S Wee; G L Schieven; J M Kirihara; T T Tsu; Jeffrey A Ledbetter; Alejandro Aruffo
Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors.
The Journal of experimental medicine 1993;177(1):219-23.
1993: P Tan; Claudio Anasetti; John A Hansen; J Melrose; M Brunvand; J Bradshaw; Jeffrey A Ledbetter; Peter Linsley
Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1.
The Journal of experimental medicine 1993;177(1):165-73.
1992: L Chen; S Ashe; W A Brady; Ingegerd Hellström; Karl Erik Hellström; Jeffrey A Ledbetter; P McGowan; Peter Linsley
Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4.
Cell 1992;71(7):1093-102.
1992: Steven B Kanner; N Odum; LS Grosmaire; S Masewicz; A Svejgaard; Jeffrey A Ledbetter
Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(11):3482-8.
1992: Diane L Hollenbaugh; LS Grosmaire; C D Kullas; N J Chalupny; S Braesch-Andersen; R J Noelle; Ivan Stamenkovic; Jeffrey A Ledbetter; Alejandro Aruffo
The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.
The EMBO journal 1992;11(12):4313-21.
1992: Peter Linsley; J L Greene; P Tan; J Bradshaw; Jeffrey A Ledbetter; Claudio Anasetti; Nitin Damle
Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes.
The Journal of experimental medicine 1992;176(6):1595-604.
1992: R Tan; Soo-Jeet Teh; Jeffrey A Ledbetter; Peter Linsley; Hung-Sia Teh
B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(10):3217-24.
1992: Alejandro Aruffo; Steven B Kanner; D Sgroi; Jeffrey A Ledbetter; Ivan Stamenkovic
CD22-mediated stimulation of T cells regulates T-cell receptor/CD3-induced signaling.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10242-6.
1992: N J Chalupny; Robert Peach; Diane L Hollenbaugh; Jeffrey A Ledbetter; Andrew G Farr; Alejandro Aruffo
T-cell activation molecule 4-1BB binds to extracellular matrix proteins.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10360-4.
1992: Nitin Damle; K Klussman; Peter Linsley; Alejandro Aruffo; Jeffrey A Ledbetter
Differential regulatory effects of intercellular adhesion molecule-1 on costimulation by the CD28 counter-receptor B7.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2541-8.
1992: fatih uckun; L Tuel-Ahlgren; Chang W Song; KG Waddick; DE Myers; J Kirihara; Jeffrey A Ledbetter; G L Schieven
Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9005-9.
1992: G L Schieven; J C Kallestad; T J Brown; Jeffrey A Ledbetter; Peter Linsley
Oncostatin M induces tyrosine phosphorylation in endothelial cells and activation of p62yes tyrosine kinase.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1676-82.
1992: Peter Linsley; PM Wallace; J Johnson; M G Gibson; J L Greene; Jeffrey A Ledbetter; C Singh; Mark Tepper
Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule.
Science (New York, N.Y.) 1992;257(5071):792-5.
1992: corinne leprince; Kevin E Draves; Jeffrey A Ledbetter; R M Torres; Edward A Clark
Characterization of molecular components associated with surface immunoglobulin M in human B lymphocytes: presence of tyrosine and serine/threonine protein kinases.
European journal of immunology 1992;22(8):2093-9.
1992: L K Gilliland; G L Schieven; N A Norris; Steven B Kanner; Alejandro Aruffo; Jeffrey A Ledbetter
Lymphocyte lineage-restricted tyrosine-phosphorylated proteins that bind PLC gamma 1 SH2 domains.
The Journal of biological chemistry 1992;267(19):13610-6.
1992: Omar Haffar; P A Moran; M D Smithgall; M L Diegel; P Sridhar; Jeffrey A Ledbetter; J M Zarling; Shiu-Lok Hu
Inhibition of virus production in peripheral blood mononuclear cells from human immunodeficiency virus (HIV) type 1-seropositive donors by treatment with recombinant HIV-like particles.
Journal of virology 1992;66(7):4279-87.
1992: Seymour J Klebanoff; S Olszowski; Wesley C Van Voorhis; Jeffrey A Ledbetter; A M Waltersdorph; K G Schlechte
Effects of gamma-interferon on human neutrophils: protection from deterioration on storage.
Blood 1992;80(1):225-34.
1992: fatih uckun; S Haissig; Jeffrey A Ledbetter; P Fidler; DE Myers; V Kuebelbeck; Daniel Weisdorf; K Gajl-Peczalska; J H Kersey; Norma K C Ramsay
Developmental hierarchy during early human B-cell ontogeny after autologous bone marrow transplantation using autografts depleted of CD19+ B-cell precursors by an anti-CD19 pan-B-cell immunotoxin containing pokeweed antiviral protein.
Blood 1992;79(12):3369-79.
1992: Jaime Sancho; Jeffrey A Ledbetter; M S Choi; Steven B Kanner; J P Deans; Cox Terhorst
CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells.
The Journal of biological chemistry 1992;267(11):7871-9.
1992: Steven B Kanner; Nitin Damle; J Blake; Alejandro Aruffo; Jeffrey A Ledbetter
CD2/LFA-3 ligation induces phospholipase-C gamma 1 tyrosine phosphorylation and regulates CD3 signaling.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(7):2023-9.
1992: Steven B Kanner; J P Deans; Jeffrey A Ledbetter
Regulation of CD3-induced phospholipase C-gamma 1 (PLC gamma 1) tyrosine phosphorylation by CD4 and CD45 receptors.
Immunology 1992;75(3):441-7.
1992: J P Deans; Steven B Kanner; R M Torres; Jeffrey A Ledbetter
Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase.
European journal of immunology 1992;22(3):661-8.
1992: Steven B Kanner; Jeffrey A Ledbetter
CD45 regulates TCR-induced signalling through tyrosine phosphorylation of phospholipase C gamma 1.
Biochemical Society transactions 1992;20(1):178-84.
1992: B M Travis; T I Dykers; D Hewgill; Jeffrey A Ledbetter; T T Tsu; Shiu-Lok Hu; J B Lewis
Functional roles of the V3 hypervariable region of HIV-1 gp160 in the processing of gp160 and in the formation of syncytia in CD4+ cells.
Virology 1992;186(1):313-7.
1992: Steven B Kanner; Terrance J Kavanagh; A Grossmann; Shiu-Lok Hu; J B Bolen; Peter S Rabinovitch; Jeffrey A Ledbetter
Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase C gamma 1.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):300-4.
1992: Jeffrey A Ledbetter; Peter Linsley
CD28 receptor crosslinking induces tyrosine phosphorylation of PLC gamma 1.
Advances in experimental medicine and biology 1992;323():23-7.
1991: N Odum; Paul J Martin; G L Schieven; N A Norris; LS Grosmaire; John A Hansen; Jeffrey A Ledbetter
Signal transduction by HLA-DR is mediated by tyrosine kinase(s) and regulated by CD45 in activated T cells.
Human immunology 1991;32(2):85-94.
1991: fatih uckun; G L Schieven; Ilker Dibirdik; M Chandan-Langlie; L Tuel-Ahlgren; Jeffrey A Ledbetter
Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the Pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny.
The Journal of biological chemistry 1991;266(26):17478-85.
1991: N Odum; Jeffrey A Ledbetter; P Martin; Daniel E Geraghty; T Tsu; John A Hansen; P Gladstone
Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies.
European journal of immunology 1991;21(9):2121-31.
1991: P S Linsley; W Brady; M Urnes; LS Grosmaire; Nitin Damle; Jeffrey A Ledbetter
CTLA-4 is a second receptor for the B cell activation antigen B7.
The Journal of experimental medicine 1991;174(3):561-9.
1991: N Odum; Paul J Martin; G L Schieven; S Masewicz; John A Hansen; Jeffrey A Ledbetter
HLA-DR molecules enhance signal transduction through the CD3/Ti complex in activated T cells.
Tissue antigens 1991;38(2):72-7.
1991: Ilker Dibirdik; MC Langlie; Jeffrey A Ledbetter; L Tuel-Ahlgren; V Obuz; KG Waddick; K Gajl-Peczalska; G L Schieven; fatih uckun
Engagement of interleukin-7 receptor stimulates tyrosine phosphorylation, phosphoinositide turnover, and clonal proliferation of human T-lineage acute lymphoblastic leukemia cells.
Blood 1991;78(3):564-70.
1991: fatih uckun; L Tuel-Ahlgren; V Obuz; R Smith; Ilker Dibirdik; M Hanson; MC Langlie; Jeffrey A Ledbetter
Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6323-7.
1991: Gitte S Jensen; E J Andrews; Michael J Mant; R Vergidis; Jeffrey A Ledbetter; Linda M Pilarski
Transitions in CD45 isoform expression indicate continuous differentiation of a monoclonal CD5+ CD11b+ B lineage in Waldenstrom's macroglobulinemia.
American journal of hematology 1991;37(1):20-30.
1991: fatih uckun; Ilker Dibirdik; R Smith; L Tuel-Ahlgren; M Chandan-Langlie; G L Schieven; KG Waddick; M Hanson; Jeffrey A Ledbetter
Interleukin 7 receptor ligation stimulates tyrosine phosphorylation, inositol phospholipid turnover, and clonal proliferation of human B-cell precursors.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3589-93.
1991: Nitin Damle; P S Linsley; Jeffrey A Ledbetter
Direct helper T cell-induced B cell differentiation involves interaction between T cell antigen CD28 and B cell activation antigen B7.
European journal of immunology 1991;21(5):1277-82.
1991: M A Valentine; M B Widmer; Jeffrey A Ledbetter; F Pinault; R Voice; Edward A Clark; Byron Gallis; D L Brautigan
Interleukin 2 stimulates serine phosphorylation of CD45 in CTLL-2.4 cells.
European journal of immunology 1991;21(4):913-9.
1991: M Parsons; M Valentine; J Deans; G L Schieven; Jeffrey A Ledbetter
Distinct patterns of tyrosine phosphorylation during the life cycle of Trypanosoma brucei.
Molecular and biochemical parasitology 1991;45(2):241-8.
1991: H P Fell; M A Gayle; LS Grosmaire; Jeffrey A Ledbetter
Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab') with specificity for carcinomas and human IL-2.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2446-52.
1991: Jeffrey A Ledbetter; LS Grosmaire; T T Tsu; G L Schieven
Tyrosine phosphorylation regulates phospholipase C activation in human T-cells.
Biochemical Society transactions 1991;19(2):269-72.
1991: L K Gilliland; Hung-Sia Teh; fatih uckun; N A Norris; Soo-Jeet Teh; G L Schieven; Jeffrey A Ledbetter
CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(6):1759-65.
1991: P J Lane; Jeffrey A Ledbetter; F M McConnell; Kevin E Draves; J Deans; G L Schieven; Edward A Clark
The role of tyrosine phosphorylation in signal transduction through surface Ig in human B cells. Inhibition of tyrosine phosphorylation prevents intracellular calcium release.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(2):715-22.
1991: N Odum; Paul J Martin; G L Schieven; John A Hansen; Jeffrey A Ledbetter
Signal transduction by HLA class II antigens expressed on activated T cells.
European journal of immunology 1991;21(1):123-9.
1991: J M Zarling; P A Moran; Omar Haffar; M Diegel; DE Myers; V Kuelbeck; Jeffrey A Ledbetter; fatih uckun
Inhibition of HIV-1 replication in seropositive patients' CD4+ T-cells by pokeweed antiviral protein-monoclonal antibody conjugates.
International journal of immunopharmacology 1991;13 Suppl 1():63-8.
1990: fatih uckun; K Gajl-Peczalska; DE Myers; WB Jaszcz; S Haissig; Jeffrey A Ledbetter
Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells.
Blood 1990;76(12):2449-56.
1990: fatih uckun; J H Kersey; D A Vallera; Jeffrey A Ledbetter; Daniel Weisdorf; DE Myers; R Haake; Norma K C Ramsay
Autologous bone marrow transplantation in high-risk remission T-lineage acute lymphoblastic leukemia using immunotoxins plus 4-hydroperoxycyclophosphamide for marrow purging.
Blood 1990;76(9):1723-33.
1990: J M Zarling; P A Moran; Omar Haffar; J Sias; D D Richman; C A Spina; DE Myers; V Kuebelbeck; Jeffrey A Ledbetter; fatih uckun
Inhibition of HIV replication by pokeweed antiviral protein targeted to CD4+ cells by monoclonal antibodies.
Nature 1990;347(6288):92-5.
1990: P S Linsley; E A Clark; Jeffrey A Ledbetter
T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5031-5.
1990: P J Lane; F M McConnell; G L Schieven; Edward A Clark; Jeffrey A Ledbetter
The role of class II molecules in human B cell activation. Association with phosphatidyl inositol turnover, protein tyrosine phosphorylation, and proliferation.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(10):3684-92.
1990: A Grossmann; Jeffrey A Ledbetter; Peter S Rabinovitch
Aging-related deficiency in intracellular calcium response to anti-CD3 or concanavalin A in murine T-cell subsets.
Journal of gerontology 1990;45(3):B81-6.
1990: J M Zarling; Jeffrey A Ledbetter; J Sias; P Fultz; J Eichberg; G Gjerset; P A Moran
HIV-infected humans, but not chimpanzees, have circulating cytotoxic T lymphocytes that lyse uninfected CD4+ cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(8):2992-8.
1990: Jeffrey A Ledbetter; L K Gilliland; G L Schieven
The interaction of CD4 with CD3/Ti regulates tyrosine phosphorylation of substrates during T cell activation.
Seminars in immunology 1990;2(2):99-106.
1990: L K Gilliland; G L Schieven; LS Grosmaire; Nitin Damle; Jeffrey A Ledbetter
CD45 ligation in T cells regulates signal transduction through both the interleukin-2 receptor and the CD3/Ti T-cell receptor complex.
Tissue antigens 1990;35(3):128-35.
1990: Michael J Gale; Jeffrey A Ledbetter; G L Schieven; M Jonker; William R Morton; Raoul E Benveniste; Edward A Clark
CD4 and CD8 T cells from SIV-infected macaques have defective signaling responses after perturbation of either CD3 or CD2 receptors.
International immunology 1990;2(9):849-58.
1989: Edward A Clark; Geraldine L Shu; Bernhard Lüscher; Kevin E Draves; Jacques Banchereau; Jeffrey A Ledbetter; M A Valentine
Activation of human B cells. Comparison of the signal transduced by IL-4 to four different competence signals.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(12):3873-80.
1989: fatih uckun; D E Myers; Jeffrey A Ledbetter; S L Wee; D A Vallera
Cell-type-specific cytotoxicity of anti-CD4 and anti-CD8 ricin immunotoxins against human alloreactive T-cell clones.
Blood 1989;74(7):2445-54.
1989: L K Gilliland; N A Norris; LS Grosmaire; S Ferrone; P Gladstone; Jeffrey A Ledbetter
Signal transduction in lymphocyte activation through crosslinking of HLA class I molecules.
Human immunology 1989;25(4):269-89.
1989: fatih uckun; A Muraguchi; Jeffrey A Ledbetter; T Kishimoto; R T O'Brien; J S Roloff; K Gajl-Peczalska; A Provisor; B Koller
Biphenotypic leukemic lymphocyte precursors in CD2+CD19+ acute lymphoblastic leukemia and their putative normal counterparts in human fetal hematopoietic tissues.
Blood 1989;73(4):1000-15.
1989: Jeffrey A Ledbetter; N A Norris; A Grossmann; LS Grosmaire; C H June; fatih uckun; W L Cosand; P S Rabinovitch
Enhanced transmembrane signalling activity of monoclonal antibody heteroconjugates suggests molecular interactions between receptors on the T cell surface.
Molecular immunology 1989;26(2):137-45.
1989: Linda M Pilarski; E J Andrews; H M Serra; Jeffrey A Ledbetter; B A Ruether; Michael J Mant
Abnormalities in lymphocyte profile and specificity repertoire of patients with Waldenstrom's macroglobulinemia, multiple myeloma, and IgM monoclonal gammopathy of undetermined significance.
American journal of hematology 1989;30(2):53-60.
1989: A Grossmann; Jeffrey A Ledbetter; Peter S Rabinovitch
Reduced proliferation in T lymphocytes in aged humans is predominantly in the CD8+ subset, and is unrelated to defects in transmembrane signaling which are predominantly in the CD4+ subset.
Experimental cell research 1989;180(2):367-82.
1988: H M Serra; Jeffrey A Ledbetter; D Neil; Linda M Pilarski
Apparent loss of 2H4+ T cells in peripheral blood lymphocytes of normal donors: a 2H4-specific artefact unique to T cells.
Human immunology 1988;23(4):281-8.
1988: Jeffrey A Ledbetter; N K Tonks; Edmond H Fischer; E A Clark
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8628-32.
1988: fatih uckun; Jeffrey A Ledbetter
Immunobiologic differences between normal and leukemic human B-cell precursors.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8603-7.
1988: Jeffrey A Ledbetter; P S Rabinovitch; Ingegerd Hellström; Karl Erik Hellström; LS Grosmaire; C H June
Role of CD2 cross-linking in cytoplasmic calcium responses and T cell activation.
European journal of immunology 1988;18(10):1601-8.
1988: P S Linsley; Jeffrey A Ledbetter; E Kinney-Thomas; S L Hu
Effects of anti-gp120 monoclonal antibodies on CD4 receptor binding by the env protein of human immunodeficiency virus type 1.
Journal of virology 1988;62(10):3695-702.
1988: L M Rose; A H Ginsberg; T L Rothstein; Jeffrey A Ledbetter; Edward A Clark
Fluctuations of CD4+ T-cell subsets in remitting-relapsing multiple sclerosis.
Annals of neurology 1988;24(2):192-9.
1988: H M Serra; Michael J Mant; B A Ruether; Jeffrey A Ledbetter; Linda M Pilarski
Selective loss of CD4+ CD45R+ T cells in peripheral blood of multiple myeloma patients.
Journal of clinical immunology 1988;8(4):259-65.
1988: M A Valentine; Edward A Clark; Geraldine L Shu; N A Norris; Jeffrey A Ledbetter
Antibody to a novel 95-kDa surface glycoprotein on human B cells induces calcium mobilization and B cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(12):4071-8.
1988: J M Zarling; P A Moran; LS Grosmaire; Janela McClure; K Shriver; Jeffrey A Ledbetter
Lysis of cells infected with HIV-1 by human lymphocytes targeted with monoclonal antibody heteroconjugates.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(8):2609-13.
1988: H M Serra; J F Krowka; Jeffrey A Ledbetter; Linda M Pilarski
Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1435-41.
1988: D A Einfeld; J P Brown; M A Valentine; E A Clark; Jeffrey A Ledbetter
Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.
The EMBO journal 1988;7(3):711-7.
1988: Edward A Clark; T C Yip; Jeffrey A Ledbetter; H Yukawa; H Kikutani; T Kishimoto; M H Ng
CDw40 and BLCa-specific monoclonal antibodies detect two distinct molecules which transmit progression signals to human B lymphocytes.
European journal of immunology 1988;18(3):451-7.
1988: fatih uckun; WB Jaszcz; J L Ambrus; Anthony Fauci; K Gajl-Peczalska; Chang W Song; M R Wick; DE Myers; KG Waddick; Jeffrey A Ledbetter
Detailed studies on expression and function of CD19 surface determinant by using B43 monoclonal antibody and the clinical potential of anti-CD19 immunotoxins.
Blood 1988;71(1):13-29.
1987: Jeffrey A Ledbetter; H P Fell; LS Grosmaire; N A Norris; T T Tsu
An immunoglobulin light chain dimer with CD4 antigen specificity.
Molecular immunology 1987;24(12):1255-61.
1987: L M Rose; Jeffrey A Ledbetter; A H Ginsberg; Edward A Clark; T L Rothstein
Suppressor-inducer T-cells in multiple sclerosis.
The New England journal of medicine 1987;317(2):118-9.
1985: L M Rose; A H Ginsberg; T L Rothstein; Jeffrey A Ledbetter; Edward A Clark
Selective loss of a subset of T helper cells in active multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(21):7389-93.