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Anthony Lee

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TOP 3
Natalie Smithers; Anthony G Lee; Juan H Bolivar; J Malcolm East
Characterizing the fatty acid binding site in the cavity of potassium channel KcsA.
Juan H Bolivar; J Malcolm East; Derek Marsh; Anthony G Lee
Effects of lipid structure on the state of aggregation of potassium channel KcsA.
Juan H Bolivar; J Malcolm East; Derek Marsh; Natalie Smithers; Anthony G Lee
Multiple binding sites for fatty acids on the potassium channel KcsA.

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All Publications

2012: Natalie Smithers; Anthony G Lee; Juan H Bolivar; J Malcolm East
Characterizing the fatty acid binding site in the cavity of potassium channel KcsA.
Biochemistry 2012;51(40):7996-8002.
2012: Juan H Bolivar; J Malcolm East; Derek Marsh; Anthony G Lee
Effects of lipid structure on the state of aggregation of potassium channel KcsA.
Biochemistry 2012;51(30):6010-6.
2012: Juan H Bolivar; J Malcolm East; Derek Marsh; Natalie Smithers; Anthony G Lee
Multiple binding sites for fatty acids on the potassium channel KcsA.
Biochemistry 2012;51(13):2889-98.
2011: John Butler; Anthony G Lee; Hans-Jurgen Schuppe; Helen R Watson; J Malcolm East
Retrieval from the ER-golgi intermediate compartment is key to the targeting of c-terminally anchored ER-resident proteins.
Journal of cellular biochemistry 2011;112(12):3543-8.
2011: Anthony G Lee
Biological membranes: the importance of molecular detail.
Trends in biochemical sciences 2011;36(9):493-500.
2011: Anthony G Lee
Lipid-protein interactions.
Biochemical Society transactions 2011;39(3):761-6.
2009: Anthony G Lee
Structural biology: Highly charged meetings.
Nature 2009;462(7272):420-1.
2009: Anthony G Lee
The effects of lipids on channel function.
Journal of biology 2009;8(9):86.
2008: Andrew Michael Powl; J Malcolm East; Anthony G Lee
Importance of direct interactions with lipids for the function of the mechanosensitive channel MscL.
Biochemistry 2008;47(46):12175-84.
2008: Andrew Michael Powl; J Malcolm East; Anthony G Lee
Anionic phospholipids affect the rate and extent of flux through the mechanosensitive channel of large conductance MscL.
Biochemistry 2008;47(14):4317-28.
2008: Phedra Marius; Michele Zagnoni; Mairi E Sandison; J Malcolm East; Hywel Morgan; Anthony G Lee
Binding of anionic lipids to at least three nonannular sites on the potassium channel KcsA is required for channel opening.
Biophysical journal 2008;94(5):1689-98.
2007: Jiraphun Jittikoon; J Malcolm East; Anthony G Lee
A fluorescence method to define transmembrane alpha-helices in membrane proteins: studies with bacterial diacylglycerol kinase.
Biochemistry 2007;46(38):10950-9.
2007: Michele Zagnoni; Mairi E Sandison; Phedra Marius; Anthony G Lee; Hywel Morgan
Controlled delivery of proteins into bilayer lipid membranes on chip.
Lab on a chip 2007;7(9):1176-83.
2007: Andrew Michael Powl; J Malcolm East; Anthony G Lee
Different effects of lipid chain length on the two sides of a membrane and the lipid annulus of MscL.
Biophysical journal 2007;93(1):113-22.
2007: joanne carney; J Malcolm East; Anthony G Lee
Penetration of lipid chains into transmembrane surfaces of membrane proteins: studies with MscL.
Biophysical journal 2007;92(10):3556-63.
2007: John Butler; Anthony G Lee; David I Wilson; Cosma Spalluto; Neil A Hanley; J Malcolm East
Phospholamban and sarcolipin are maintained in the endoplasmic reticulum by retrieval from the ER-Golgi intermediate compartment.
Cardiovascular research 2007;74(1):114-23.
2006: Sanjay Mall; Robert J Broadbridge; Steven L Harrison; Michael G Gore; Anthony G Lee; J Malcolm East
The presence of sarcolipin results in increased heat production by Ca(2+)-ATPase.
The Journal of biological chemistry 2006;281(48):36597-602.
2006: joanne carney; J Malcolm East; Sanjay Mall; Phedra Marius; Andrew Michael Powl; J Neville Wright; Anthony G Lee
Fluorescence quenching methods to study lipid-protein interactions.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2006;Chapter 19():Unit 19.12.
2005: Phedra Marius; Simon J Alvis; J Malcolm East; Anthony G Lee
The interfacial lipid binding site on the potassium channel KcsA is specific for anionic phospholipids.
Biophysical journal 2005;89(6):4081-9.
2005: Andrew Michael Powl; joanne carney; Phedra Marius; J Malcolm East; Anthony G Lee
Lipid interactions with bacterial channels: fluorescence studies.
Biochemical Society transactions 2005;33(Pt 5):905-9.
2005: Anthony G Lee
How lipids and proteins interact in a membrane: a molecular approach.
Molecular bioSystems 2005;1(3):203-12.
2005: Anthony G Lee
Lipid sorting: lipids do it on their own.
Current biology : CB 2005;15(11):R421-3.
2005: Andrew Michael Powl; J Malcolm East; Anthony G Lee
Heterogeneity in the binding of lipid molecules to the surface of a membrane protein: hot spots for anionic lipids on the mechanosensitive channel of large conductance MscL and effects on conformation.
Biochemistry 2005;44(15):5873-83.
2005: Andrew Michael Powl; J Neville Wright; J Malcolm East; Anthony G Lee
Identification of the hydrophobic thickness of a membrane protein using fluorescence spectroscopy: studies with the mechanosensitive channel MscL.
Biochemistry 2005;44(15):5713-21.
2004: Anthony G Lee
How lipids affect the activities of integral membrane proteins.
Biochimica et biophysica acta 2004;1666(1-2):62-87.
2003: Andrew Michael Powl; J Malcolm East; Anthony G Lee
Lipid-protein interactions studied by introduction of a tryptophan residue: the mechanosensitive channel MscL.
Biochemistry 2003;42(48):14306-17.
2003: Simon J Alvis; Ian M Williamson; J Malcolm East; Anthony G Lee
Interactions of anionic phospholipids and phosphatidylethanolamine with the potassium channel KcsA.
Biophysical journal 2003;85(6):3828-38.
2003: Elizabeth H Clark; J Malcolm East; Anthony G Lee
The role of tryptophan residues in an integral membrane protein: diacylglycerol kinase.
Biochemistry 2003;42(37):11065-73.
2003: Anthony G Lee
How phospholamban could affect the apparent affinity of Ca(2+)-ATPase for Ca(2+) in kinetic experiments.
FEBS letters 2003;551(1-3):37-41.
2003: Ursula Eckstein-Ludwig; RJ Webb; I D A Van Goethem; J Malcolm East; Anthony G Lee; M Kimura; Paul M O'Neill; Patrick G Bray; S A Ward; Sanjeev Krishna
Artemisinins target the SERCA of Plasmodium falciparum.
Nature 2003;424(6951):957-61.
2003: Ian M Williamson; Simon J Alvis; J Malcolm East; Anthony G Lee
The potassium channel KcsA and its interaction with the lipid bilayer.
Cellular and molecular life sciences : CMLS 2003;60(8):1581-90.
2003: Anthony G Lee
Lipid-protein interactions in biological membranes: a structural perspective.
Biochimica et biophysica acta 2003;1612(1):1-40.
2003: Thomas Newton; John P J Black; John Butler; Anthony G Lee; John Chad; J Malcolm East
Sarco/endoplasmic-reticulum calcium ATPase SERCA1 is maintained in the endoplasmic reticulum by a retrieval signal located between residues 1 and 211.
The Biochemical journal 2003;371(Pt 3):775-82.
2002: Anthony G Lee
Ca2+ -ATPase structure in the E1 and E2 conformations: mechanism, helix-helix and helix-lipid interactions.
Biochimica et biophysica acta 2002;1565(2):246-66.
2002: Ian M Williamson; Simon J Alvis; J Malcolm East; Anthony G Lee
Interactions of phospholipids with the potassium channel KcsA.
Biophysical journal 2002;83(4):2026-38.
2002: Anthony G Lee
A calcium pump made visible.
Current opinion in structural biology 2002;12(4):547-54.
2002: Melanie J Logan-Smith; J Malcolm East; Anthony G Lee
Evidence for a global inhibitor-induced conformation change on the Ca(2+)-ATPase of sarcoplasmic reticulum from paired inhibitor studies.
Biochemistry 2002;41(8):2869-75.
2002: Wendy S Smith; Robert J Broadbridge; J Malcolm East; Anthony G Lee
Sarcolipin uncouples hydrolysis of ATP from accumulation of Ca2+ by the Ca2+-ATPase of skeletal-muscle sarcoplasmic reticulum.
The Biochemical journal 2002;361(Pt 2):277-86.
2001: M J Logan-Smith; P J Lockyer; J Malcolm East; Anthony G Lee
Curcumin, a molecule that inhibits the Ca2+-ATPase of sarcoplasmic reticulum but increases the rate of accumulation of Ca2+.
The Journal of biological chemistry 2001;276(50):46905-11.
2001: JD Pilot; J Malcolm East; Anthony G Lee
Effects of phospholipid headgroup and phase on the activity of diacylglycerol kinase of Escherichia coli.
Biochemistry 2001;40(49):14891-7.
2001: Sanjay Mall; Robert J Broadbridge; RP Sharma; J Malcolm East; Anthony G Lee
Self-association of model transmembrane alpha-helices is modulated by lipid structure.
Biochemistry 2001;40(41):12379-86.
2001: JD Pilot; J Malcolm East; Anthony G Lee
Effects of bilayer thickness on the activity of diacylglycerol kinase of Escherichia coli.
Biochemistry 2001;40(28):8188-95.
2001: Anthony G Lee; J Malcolm East
What the structure of a calcium pump tells us about its mechanism.
The Biochemical journal 2001;356(Pt 3):665-83.
2001: Anthony G Lee
Myelin: Delivery by raft.
Current biology : CB 2001;11(2):R60-2.
2000: A H O'Keeffe; J Malcolm East; Anthony G Lee
Selectivity in lipid binding to the bacterial outer membrane protein OmpF.
Biophysical journal 2000;79(4):2066-74.
2000: Anthony G Lee
Membrane lipids: it's only a phase.
Current biology : CB 2000;10(10):R377-80.
2000: Sanjay Mall; Robert J Broadbridge; RP Sharma; Anthony G Lee; J Malcolm East
Effects of aromatic residues at the ends of transmembrane alpha-helices on helix interactions with lipid bilayers.
Biochemistry 2000;39(8):2071-8.
2000: RJ Webb; Y M Khan; J Malcolm East; Anthony G Lee
The importance of carboxyl groups on the lumenal side of the membrane for the function of the Ca(2+)-ATPase of sarcoplasmic reticulum.
The Journal of biological chemistry 2000;275(2):977-82.
1999: KA Dalton; JD Pilot; Sanjay Mall; J Malcolm East; Anthony G Lee
Anionic phospholipids decrease the rate of slippage on the Ca(2+)-ATPase of sarcoplasmic reticulum.
The Biochemical journal 1999;342 ( Pt 2)():431-8.
1999: R C Duggleby; M East; Anthony G Lee
Luminal dissociation of Ca2+ from the phosphorylated Ca2+-ATPase is sequential and gated by Mg2+.
The Biochemical journal 1999;339 ( Pt 2)():351-7.
1998: Anthony G Lee
How lipids interact with an intrinsic membrane protein: the case of the calcium pump.
Biochimica et biophysica acta 1998;1376(3):381-90.
1998: P Adams; J Malcolm East; Anthony G Lee; C David O'Connor
Mutational analysis of trans-membrane helices M3, M4, M5 and M7 of the fast-twitch Ca2+-ATPase.
The Biochemical journal 1998;335 ( Pt 1)():131-8.
1998: RJ Webb; Anthony G Lee; RP Sharma; J Malcolm East
Transmembrane alpha-helices in phospholipid bilayers.
Biochemical Society transactions 1998;26(3):S309.
1998: J P Black; John Chad; Anthony G Lee; J Malcolm East
Identification of endoplasmic reticulum targeting signals using SERCA/PMCA chimeras.
Biochemical Society transactions 1998;26(3):S299.
1998: I D A Van Goethem; P Adams; John Chad; A M Mather; B Griffiths; Anthony G Lee; J Malcolm East
Localization of endoplasmic reticulum in living cells using green fluorescent protein chimeras.
Biochemical Society transactions 1998;26(3):S298.
1998: S M Twine; Anthony G Lee; Michael G Gore; B C Fish; A Turner; M J East
Characterisation of domain fragments of recombinant human albumin.
Biochemical Society transactions 1998;26(3):S279.
1998: KA Dalton; Sanjay Mall; JD Pilot; J Malcolm East; Anthony G Lee
Anionic lipids and accumulation of Ca2+ by a Ca(2+)-ATPase.
Biochemical Society transactions 1998;26(3):S234.
1998: Anthony G Lee; J Malcolm East
The effects of phospholipid structure on the function of a calcium pump.
Biochemical Society transactions 1998;26(3):359-65.
1998: P J Lockyer; E Puente; J Windass; F Earley; J Malcolm East; Anthony G Lee
Cloning and expression of an insect Ca(2+)-ATPase from Heliothis virescens.
Biochimica et biophysica acta 1998;1369(1):14-8.
1998: KA Dalton; J Malcolm East; Sanjay Mall; S Oliver; A P Starling; Anthony G Lee
Interaction of phosphatidic acid and phosphatidylserine with the Ca2+-ATPase of sarcoplasmic reticulum and the mechanism of inhibition.
The Biochemical journal 1998;329 ( Pt 3)():637-46.
1998: RJ Webb; J Malcolm East; RP Sharma; Anthony G Lee
Hydrophobic mismatch and the incorporation of peptides into lipid bilayers: a possible mechanism for retention in the Golgi.
Biochemistry 1998;37(2):673-9.
1998: Sanjay Mall; RP Sharma; J Malcolm East; Anthony G Lee
Lipid-protein interactions in the membrane: studies with model peptides.
Faraday discussions 1998;(111):127-36; discussion 137-57.
1997: I D A Van Goethem; John Chad; Anthony G Lee; S D Jane; J Malcolm East
Location of endoplasmic reticulum relative to sarcoplasmic reticulum in cultured chick myotubes.
Biochemical Society transactions 1997;25(1):9S.
1997: Y M Khan; J Malcolm East; Anthony G Lee
Effects of pH on phosphorylation of the Ca2+-ATPase of sarcoplasmic reticulum by inorganic phosphate.
The Biochemical journal 1997;321 ( Pt 3)():671-6.
1996: A P Starling; K A Dalton; J Malcolm East; S Oliver; Anthony G Lee
Effects of phosphatidylethanolamines on the activity of the Ca(2+)-ATPase of sarcoplasmic reticulum.
The Biochemical journal 1996;320 ( Pt 1)():309-14.
1996: A P Starling; J Malcolm East; Anthony G Lee
Stimulation of the Ca(2+)-ATPase of sarcoplasmic reticulum by disulfiram.
The Biochemical journal 1996;320 ( Pt 1)():101-5.
1996: G Hughes; A P Starling; R P Sharma; J Malcolm East; Anthony G Lee
An investigation of the mechanism of inhibition of the Ca(2+)-ATPase by phospholamban.
The Biochemical journal 1996;318 ( Pt 3)():973-9.
1996: A P Starling; J Malcolm East; Anthony G Lee
Separate effects of long-chain phosphatidylcholines on dephosphorylation of the Ca(2+)-ATPase and on Ca2+ binding.
The Biochemical journal 1996;318 ( Pt 3)():785-8.
1996: A P Starling; R P Sharma; J Malcolm East; Anthony G Lee
The effect of N-terminal acetylation on Ca(2+)-ATPase inhibition by phospholamban.
Biochemical and biophysical research communications 1996;226(2):352-5.
1996: Y M Khan; A P Starling; J Malcolm East; Anthony G Lee
The mechanism of inhibition of the Ca(2+)-ATPase of skeletal-muscle sarcoplasmic reticulum by the cross-linker o-phthalaldehyde.
The Biochemical journal 1996;317 ( Pt 2)():439-45.
1996: Y M Khan; M Wictome; J Malcolm East; Anthony G Lee
Labelling the Ca(2+)-ATPase of skeletal-muscle sarcoplasmic reticulum with the cross-linker o-phthalaldehyde.
The Biochemical journal 1996;317 ( Pt 2)():433-7.
1995: Y M Khan; M Wictome; J Malcolm East; Anthony G Lee
Interactions of dihydroxybenzenes with the Ca(2+)-ATPase: separate binding sites for dihydroxybenzenes and sesquiterpene lactones.
Biochemistry 1995;34(44):14385-93.
1995: A P Starling; G Hughes; R P Sharma; J Malcolm East; Anthony G Lee
The hydrophilic domain of phospholamban inhibits the Ca(2+)-ATPase--the importance of the method of assay.
Biochemical and biophysical research communications 1995;215(3):1067-70.
1995: Anthony G Lee; K A Dalton; R C Duggleby; J Malcolm East; A P Starling
Lipid structure and Ca(2+)-ATPase function.
Bioscience reports 1995;15(5):289-98.
1995: A P Starling; J Malcolm East; Anthony G Lee
Effects of phospholipid fatty acyl chain length on phosphorylation and dephosphorylation of the Ca(2+)-ATPase.
The Biochemical journal 1995;310 ( Pt 3)():875-9.
1995: M Wictome; Y M Khan; J Malcolm East; Anthony G Lee
Binding of sesquiterpene lactone inhibitors to the Ca(2+)-ATPase.
The Biochemical journal 1995;310 ( Pt 3)():859-68.
1995: A P Starling; J Malcolm East; Anthony G Lee
Phosphatidylinositol 4-phosphate increases the rate of dephosphorylation of the phosphorylated Ca(2+)-ATPase.
The Journal of biological chemistry 1995;270(24):14467-70.
1995: G Hughes; Y M Khan; J Malcolm East; Anthony G Lee
Effects of polycations on Ca2+ binding to the Ca(2+)-ATPase.
The Biochemical journal 1995;308 ( Pt 2)():493-9.
1995: A P Starling; J Malcolm East; Anthony G Lee
Evidence that the effects of phospholipids on the activity of the Ca(2+)-ATPase do not involve aggregation.
The Biochemical journal 1995;308 ( Pt 1)():343-6.
1995: K J Baker; J Malcolm East; Anthony G Lee
Mechanism of inhibition of Ca(2+)-ATPase by myotoxin a.
The Biochemical journal 1995;307 ( Pt 2)():571-9.
1995: J Ding; J Malcolm East; Anthony G Lee
Synthesis of phospholipid-based detergents and their effects on the Ca(2+)-ATPase of sarcoplasmic reticulum.
Biochimica et biophysica acta 1995;1234(2):166-72.
1995: K J Baker; J Malcolm East; Anthony G Lee
Mechanism of inhibition of the Ca(2+)-ATPase by melittin.
Biochemistry 1995;34(11):3596-604.
1995: A P Starling; J Malcolm East; Anthony G Lee
Effects of gel phase phospholipid on the Ca(2+)-ATPase.
Biochemistry 1995;34(9):3084-91.
1995: Anthony G Lee; K Baker; Y M Khan; J Malcolm East
Effects of K+ on the binding of Ca2+ to the Ca(2+)-ATPase of sarcoplasmic reticulum.
The Biochemical journal 1995;305 ( Pt 1)():225-31.
1994: A P Starling; Y M Khan; J Malcolm East; Anthony G Lee
Characterization of the single Ca(2+)-binding site on the Ca(2+)-ATPase reconstituted with short- or long-chain phosphatidylcholines.
The Biochemical journal 1994;304 ( Pt 2)():569-75.
1994: G R Brown; S L Benyon; C J Kirk; M Wictome; J Malcolm East; Anthony G Lee; Francesco Michelangeli
Characterisation of a novel Ca2+ pump inhibitor (bis-phenol) and its effects on intracellular Ca2+ mobilization.
Biochimica et biophysica acta 1994;1195(2):252-8.
1994: G Hughes; J Malcolm East; Anthony G Lee
The hydrophilic domain of phospholamban inhibits the Ca2+ transport step of the Ca(2+)-ATPase.
The Biochemical journal 1994;303 ( Pt 2)():511-6.
1994: Anthony G Lee; A P Starling; J Ding; J Malcolm East; M Wictome
Lipid-protein interactions and Ca(2+)-ATPase function.
Biochemical Society transactions 1994;22(3):821-6.
1994: K J Baker; J Malcolm East; Anthony G Lee
Localization of the hinge region of the Ca(2+)-ATPase of sarcoplasmic reticulum using resonance energy transfer.
Biochimica et biophysica acta 1994;1192(1):53-60.
1994: J Ding; A P Starling; J Malcolm East; Anthony G Lee
Binding sites for cholesterol on Ca(2+)-ATPase studied by using a cholesterol-containing phospholipid.
Biochemistry 1994;33(16):4974-9.
1994: G Hughes; A P Starling; J Malcolm East; Anthony G Lee
Mechanism of inhibition of the Ca(2+)-ATPase by spermine and other polycationic compounds.
Biochemistry 1994;33(16):4745-54.
1994: M Wictome; M Holub; J Malcolm East; Anthony G Lee
The importance of the hydroxyl moieties for inhibition of the Ca(2+)-ATPase by trilobolide and 2,5-di(tert-butyl)-1,4-benzohydroquinone.
Biochemical and biophysical research communications 1994;199(2):916-21.
1994: A P Starling; G Hughes; J Malcolm East; Anthony G Lee
Mechanism of stimulation of the calcium adenosinetriphosphatase by jasmone.
Biochemistry 1994;33(10):3023-31.
1994: I M Henderson; A P Starling; M Wictome; J Malcolm East; Anthony G Lee
Binding of Ca2+ to the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum: kinetic studies.
The Biochemical journal 1994;297 ( Pt 3)():625-36.
1994: I M Henderson; Y M Khan; J Malcolm East; Anthony G Lee
Binding of Ca2+ to the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum: equilibrium studies.
The Biochemical journal 1994;297 ( Pt 3)():615-24.
1994: Anthony G Lee
Measurement of protein-protein interactions in reconstituted membrane vesicles using fluorescence spectroscopy.
Methods in molecular biology (Clifton, N.J.) 1994;27():95-100.
1994: Anthony G Lee
Measurement of lipid-protein interactions in reconstituted membrane vesicles using fluorescence spectroscopy.
Methods in molecular biology (Clifton, N.J.) 1994;27():101-7.
1993: M Wictome; A P Starling; R P Sharma; J Malcolm East; Anthony G Lee
Inhibition of the Ca(2+)-ATPase by sesquiterpene lactones.
Biochemical Society transactions 1993;21(4):348S.
1993: H I Stefanova; Ana Mata; Michael G Gore; J Malcolm East; Anthony G Lee
Labeling the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum at Glu-439 with 5-(bromomethyl)fluorescein.
Biochemistry 1993;32(23):6095-103.
1993: Ana Mata; H I Stefanova; Michael G Gore; Y M Khan; J Malcolm East; Anthony G Lee
Localization of Cys-344 on the (Ca(2+)-Mg(2+)-ATPase of sarcoplasmic reticulum using resonance energy transfer.
Biochimica et biophysica acta 1993;1147(1):6-12.
1993: I Matthews; Ana Mata; Anthony G Lee; J Malcolm East
Evidence for the lumenal location of the 53 kDa glycoprotein of sarcoplasmic reticulum.
Biochimica et biophysica acta 1993;1146(2):265-74.
1993: A P Starling; J Malcolm East; Anthony G Lee
Effects of phosphatidylcholine fatty acyl chain length on calcium binding and other functions of the (Ca(2+)-Mg2+)-ATPase.
Biochemistry 1993;32(6):1593-600.
1993: H I Stefanova; Ana Mata; J Malcolm East; Michael G Gore; Anthony G Lee
Reactivity of lysyl residues on the (Ca(2+)-Mg2+)-ATPase to 7-amino-4-methylcoumarin-3-acetic acid succinimidyl ester.
Biochemistry 1993;32(1):356-62.
1992: Ana Mata; I Matthews; R E Tunwell; R P Sharma; Anthony G Lee; J Malcolm East
Definition of surface-exposed and trans-membranous regions of the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum using anti-peptide antibodies.
The Biochemical journal 1992;286 ( Pt 2)():567-80.
1992: J Malcolm East; I Matthews; R E Tunwell; Ana Mata; Anthony G Lee
Studies of the structure and function of sarcoplasmic reticulum (Ca(2+)-Mg2+)-ATPase using immunological approaches.
Biochemical Society transactions 1992;20(3):550-4.
1992: Ana Mata; I Matthews; Anthony G Lee; J Malcolm East
An examination of the transmembranous organisation of the sarcoplasmic reticulum (Ca(2+)-Mg2+)-ATPase using antipeptide antibodies.
Biochemical Society transactions 1992;20(3):308S.
1992: M P Wictome; Anthony G Lee; J Malcolm East
Mechanism of action of Ca(2+)-ATPase inhibitors.
Biochemical Society transactions 1992;20(3):249S.
1992: H I Stefanova; J Malcolm East; Michael G Gore; Anthony G Lee
Labeling the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum with 4-(bromomethyl)-6,7-dimethoxycoumarin: detection of conformational changes.
Biochemistry 1992;31(26):6023-31.
1992: M Wictome; Francesco Michelangeli; Anthony G Lee; J Malcolm East
The inhibitors thapsigargin and 2,5-di(tert-butyl)-1,4-benzohydroquinone favour the E2 form of the Ca2+,Mg(2+)-ATPase.
FEBS letters 1992;304(2-3):109-13.
1992: Ana Mata; R E Tunwell; Anthony G Lee; J Malcolm East
Definition of an epitope at the nucleotide binding site of the (Ca(2+)-Mg(2+)-ATPase of sarcoplasmic reticulum by fluorescein labelling.
Biochemical Society transactions 1992;20(2):123S.
1992: M Wictome; I Henderson; Anthony G Lee; J Malcolm East
Mechanism of inhibition of the calcium pump of sarcoplasmic reticulum by thapsigargin.
The Biochemical journal 1992;283 ( Pt 2)():525-9.
1991: R E Tunwell; J W Conlan; I Matthews; J Malcolm East; Anthony G Lee
Definition of surface-exposed epitopes on the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum.
The Biochemical journal 1991;279 ( Pt 1)():203-12.
1991: E A Grimes; A J Burgess; J Malcolm East; Anthony G Lee
Reconstitution experiments provide no evidence for a role for the 53-kDa glycoprotein in coupling Ca2+ transport to ATP hydrolysis by the (Ca(2+)-Mg2+)-ATPase in sarcoplasmic reticulum.
Biochimica et biophysica acta 1991;1064(2):335-42.
1991: H I Stefanova; J Malcolm East; Anthony G Lee
Covalent and non-covalent inhibitors of the phosphate transporter of sarcoplasmic reticulum.
Biochimica et biophysica acta 1991;1064(2):321-8.
1991: H I Stefanova; S D Jane; J Malcolm East; Anthony G Lee
Effects of Mg2+ and ATP on the phosphate transporter of sarcoplasmic reticulum.
Biochimica et biophysica acta 1991;1064(2):329-34.
1991: A J Burgess; I Matthews; E A Grimes; Ana Mata; F M Munkonge; Anthony G Lee; J Malcolm East
Chemical crosslinking and enzyme kinetics provide no evidence for a regulatory role for the 53 kDa glycoprotein of sarcoplasmic reticulum in calcium transport.
Biochimica et biophysica acta 1991;1064(1):139-47.
1991: R E Tunwell; C David O'Connor; Ana Mata; J Malcolm East; Anthony G Lee
Mapping epitopes on the (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum using fusion proteins.
Biochimica et biophysica acta 1991;1073(3):585-92.
1991: Ana Mata; J Colyer; Francesco Michelangeli; Anthony G Lee; J Malcolm East
The effect of a monoclonal antibody on specific steps of the reaction sequence of the (Ca(2+)-Mg(2+))-ATPase from sarcoplasmic reticulum.
Biochemical Society transactions 1991;19(2):205S.
1991: Francesco Michelangeli; E A Grimes; J Malcolm East; Anthony G Lee
Effects of phospholipids on the function of (Ca2(+)-Mg2+)-ATPase.
Biochemistry 1991;30(2):342-51.
1991: Anthony G Lee
Lipids and their effects on membrane proteins: evidence against a role for fluidity.
Progress in lipid research 1991;30(4):323-48.
1990: I Matthews; R P Sharma; Anthony G Lee; J Malcolm East
Transmembranous organization of (Ca2(+)-Mg2+)-ATPase from sarcoplasmic reticulum. Evidence for lumenal location of residues 877-888.
The Journal of biological chemistry 1990;265(31):18737-40.
1990: Francesco Michelangeli; M J Robson; J Malcolm East; Anthony G Lee
The conformation of pyrethroids bound to lipid bilayers.
Biochimica et biophysica acta 1990;1028(1):49-57.
1990: Francesco Michelangeli; M J Robson; J Malcolm East; Anthony G Lee
Fluorescence and kinetic studies of the interactions of pyrethroids with the (Ca2(+) + Mg2+)-ATPase.
Biochimica et biophysica acta 1990;1028(1):58-66.
1990: Francesco Michelangeli; S Orlowski; Philippe Champeil; E A Grimes; J Malcolm East; Anthony G Lee
Effects of phospholipids on binding of calcium to (Ca2(+)-Mg2(+)-ATPase.
Biochemistry 1990;29(36):8307-12.
1990: Ana Mata; Francesco Michelangeli; Anthony G Lee; J Malcolm East
Effect of the detergent C12E8 on the binding of monoclonal antibodies to the (Ca2(+)-Mg2+)-ATPase of rabbit skeletal sarcoplasmic reticulum.
Biochemical Society transactions 1990;18(4):603.
1990: Francesco Michelangeli; J Malcolm East; Anthony G Lee
Structural effects on the interaction of sterols with the (Ca2+ + Mg2+)-ATPase.
Biochimica et biophysica acta 1990;1025(1):99-108.
1990: Francesco Michelangeli; J Colyer; J Malcolm East; Anthony G Lee
Effect of pH on the activity of the Ca2+ + Mg2(+)-activated ATPase of sarcoplasmic reticulum.
The Biochemical journal 1990;267(2):423-9.
1990: Francesco Michelangeli; S Orlowski; Philippe Champeil; J Malcolm East; Anthony G Lee
Mechanism of inhibition of the (Ca2(+)-Mg2+)-ATPase by nonylphenol.
Biochemistry 1990;29(12):3091-101.
1989: Anthony G Lee; Francesco Michelangeli; J Malcolm East
Tests for the importance of fluidity for the function of membrane proteins.
Biochemical Society transactions 1989;17(6):962-4.
1989: Ana Mata; A E Schofield; J Woodbine; Anthony G Lee; J Malcolm East
Probing the nucleotide binding site of sarcoplasmic reticulum (Ca2(+)-Mg2)-ATPase with anti-fluorescein antibodies.
Biochemical Society transactions 1989;17(6):1105-6.
1989: E A Grimes; F M Munkonge; I Matthews; A Burgess; Ana Mata; Francesco Michelangeli; J Malcolm East; Anthony G Lee
Use of antibodies to detect chemically cross-linked products from sarcoplasmic reticulum.
Biochemical Society transactions 1989;17(6):1103-4.
1989: Francesco Michelangeli; I Henderson; J Malcolm East; Anthony G Lee
Interaction of sterols with phospholipid bilayers and the (Ca2(+)-Mg2+)-ATPase.
Biochemical Society transactions 1989;17(6):1095-6.
1989: J Colyer; Ana Mata; Anthony G Lee; J Malcolm East
Effects on ATPase activity of monoclonal antibodies raised against (Ca2+ + Mg2+)-ATPase from rabbit skeletal muscle sarcoplasmic reticulum and their correlation with epitope location.
The Biochemical journal 1989;262(2):439-47.
1989: Ana Mata; Anthony G Lee; J Malcolm East
Probing the nucleotide-binding site of sarcoplasmic reticulum (Ca2+-Mg2+)-ATPase with anti-fluorescein antibodies.
FEBS letters 1989;253(1-2):273-5.
1989: I Matthews; J Colyer; Ana Mata; N M Green; R P Sharma; Anthony G Lee; J Malcolm East
Evidence for the cytoplasmic location of the N- and C-terminal segments of sarcoplasmic reticulum (Ca2+-Mg2+)-ATPase.
Biochemical and biophysical research communications 1989;161(2):683-8.
1989: Béatrice de Foresta; Marc le Maire; S Orlowski; Philippe Champeil; S Lund; Jesper V Møller; F Michelangeli; Anthony G Lee
Membrane solubilization by detergent: use of brominated phospholipids to evaluate the detergent-induced changes in Ca2+-ATPase/lipid interaction.
Biochemistry 1989;28(6):2558-67.
1989: F Munkonge; J Malcolm East; Anthony G Lee
Positions of the sites labeled by N-cyclohexyl-N'-(4-dimethylamino-1-naphthyl)carbodiimide on the (Ca2+ + Mg2+)-ATPase.
Biochimica et biophysica acta 1989;979(1):113-20.
1988: F Munkonge; Francesco Michelangeli; E K Rooney; J Malcolm East; Anthony G Lee
Effect of phospholipid:protein ratio on the state of aggregation of the (Ca2+-Mg2+)-ATPase.
Biochemistry 1988;27(18):6800-5.
1987: G W Gould; J M McWhirter; J Malcolm East; Anthony G Lee
A fast passive Ca2+ efflux mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles.
Biochimica et biophysica acta 1987;904(1):45-54.
1987: G W Gould; J M McWhirter; J Malcolm East; Anthony G Lee
Uptake of Ca2+ mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles.
Biochimica et biophysica acta 1987;904(1):36-44.
1987: R M Napier; J Malcolm East; Anthony G Lee
State of aggregation of the (Ca2+ + Mg2+)-ATPase studied using chemical cross-linking.
Biochimica et biophysica acta 1987;903(2):374-80.
1987: R M Napier; J Malcolm East; Anthony G Lee
State of aggregation of the (Ca2+ + Mg2+)-ATPase studied using saturation-transfer electron spin resonance.
Biochimica et biophysica acta 1987;903(2):365-73.
1987: J M McWhirter; G W Gould; J Malcolm East; Anthony G Lee
Characterization of Ca2+ uptake and release by vesicles of skeletal-muscle sarcoplasmic reticulum.
The Biochemical journal 1987;245(3):731-8.
1987: G W Gould; J M McWhirter; J Malcolm East; Anthony G Lee
Effects of diet on the function of sarcoplasmic reticulum.
The Biochemical journal 1987;245(3):751-5.
1987: G W Gould; J M McWhirter; J Malcolm East; Anthony G Lee
A model for the uptake and release of Ca2+ by sarcoplasmic reticulum.
The Biochemical journal 1987;245(3):739-49.
1987: H I Stefanova; R M Napier; J Malcolm East; Anthony G Lee
Effects of Mg2+, anions and cations on the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum.
The Biochemical journal 1987;245(3):723-30.
1987: J M McWhirter; G W Gould; J Malcolm East; Anthony G Lee
A kinetic model for Ca2+ efflux mediated by the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum.
The Biochemical journal 1987;245(3):713-21.
1987: C Gutierrez-Merino; F Munkonge; Ana Mata; J Malcolm East; B L Levinson; R M Napier; Anthony G Lee
The position of the ATP binding site on the (Ca2+ + Mg2+)-ATPase.
Biochimica et biophysica acta 1987;897(2):207-16.
1986: Anthony G Lee; J M East; R J Froud
Are essential fatty acids essential for membrane function?
Progress in lipid research 1986;25(1-4):41-6.