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Chih-Hung Lee

Research Profile

Chemicals & Drugs

Physiology

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Publications

TOP 3
Michael J Liguori; Hong Liu; Kennan C Marsh; Jeffrey F Waring; Mark E Andracki; Eric A G Blomme; Rita Ciurlionis; Amy C Ditewig; Stella Doktor; Gerard Gagne; Murali Gopalakrishnan; Chih-Hung Lee; Yi Yang
AhR activation underlies the CYP1A autoinduction by A-998679 in rats.
Marc J C Scanio; Lei Shi; Kirsten K Thorin-Hagene; Ceclia E Van Handel; Rosalind J Helfrich; Chih-Hung Lee; Jens Halvard Gronlien; Kennan Marsh; David J Anderson; William H Bunnelle; Murali Gopalakrishnan
Structure-activity studies of diazabicyclo[3.3.0]octane-substituted pyrazines and pyridines as potent α4β2 nicotinic acetylcholine receptor ligands.
Chih-Hung Lee; Jens Halvard Gronlien; James Polakowski; Thomas Shaughnessy; Chang Zhu; Thomas Campbell; Prisca Honore; Murali Gopalakrishnan
α4β2 neuronal nicotinic receptor positive allosteric modulation: an approach for improving the therapeutic index of α4β2 nAChR agonists in pain.

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All Publications

2012: Michael J Liguori; Hong Liu; Kennan C Marsh; Jeffrey F Waring; Mark E Andracki; Eric A G Blomme; Rita Ciurlionis; Amy C Ditewig; Stella Doktor; Gerard Gagne; Murali Gopalakrishnan; Chih-Hung Lee; Yi Yang
AhR activation underlies the CYP1A autoinduction by A-998679 in rats.
Frontiers in genetics 2012;3():213.
2011: Marc J C Scanio; Lei Shi; Kirsten K Thorin-Hagene; Ceclia E Van Handel; Rosalind J Helfrich; Chih-Hung Lee; Jens Halvard Gronlien; Kennan Marsh; David J Anderson; William H Bunnelle; Murali Gopalakrishnan
Structure-activity studies of diazabicyclo[3.3.0]octane-substituted pyrazines and pyridines as potent α4β2 nicotinic acetylcholine receptor ligands.
Journal of medicinal chemistry 2011;54(21):7678-92.
2011: Chih-Hung Lee; Jens Halvard Gronlien; James Polakowski; Thomas Shaughnessy; Chang Zhu; Thomas Campbell; Prisca Honore; Murali Gopalakrishnan
α4β2 neuronal nicotinic receptor positive allosteric modulation: an approach for improving the therapeutic index of α4β2 nAChR agonists in pain.
Biochemical pharmacology 2011;82(8):959-66.
2011: Chang Z Zhu; Scott Baker; Jordan Brown; Prasant Chandran; Chih-Liang Chin; Michael W Decker; Gerard B Fox; Donna Gauvin; Erica Gomez; Murali Gopalakrishnan; Peer B Jacobson; Victoria A Komater; Chih-Hung Lee; La Geisha Lewis; Joe Mikusa; Madhavi Pai; Nathan R Rustay; Anita Salyers; Gricelda Simler; A Tovcimak; Chengmin Zhong; Prisca Honore
Potentiation of analgesic efficacy but not side effects: co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats.
Biochemical pharmacology 2011;82(8):967-76.
2011: Robert G Schmidt; Erol K Bayburt; Steven P Latshaw; John R Koenig; Jerome F Daanen; Heath A McDonald; Bruce R Bianchi; Chengmin Zhong; Shailen Joshi; Prisca Honore; Kennan Marsh; Chih-Hung Lee; Connie R Faltynek; Arthur Gomtsyan
Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 2011;21(5):1338-41.
2010: Hilde Ween; Kirsten Thorin-Hagene; Elisabeth Andersen; Jens Halvard Grønlien; Chih-Hung Lee; Murali Gopalakrishnan; John Malysz
Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells.
Neurochemistry international 2010;57(3):269-77.