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Chih-Hao Lee

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Oligonucleotide Array Sequence Analysis

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Kacey L Caradonna; Juan C Engel; David Jacobi; Chih-Hao Lee; Barbara A Burleigh
Host metabolism regulates intracellular growth of Trypanosoma cruzi.
Prerna Bhargava; Lingling Dai; Matthew R Gangl; Donald A Harn; David Jacobi; Changlin Li; Sihao Liu; Kristopher J Stanya; Chih-Hao Lee
Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways.
Prerna Bhargava; Chih-Hao Lee
Role and function of macrophages in the metabolic syndrome.

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All Publications

2013: Kacey L Caradonna; Juan C Engel; David Jacobi; Chih-Hao Lee; Barbara A Burleigh
Host metabolism regulates intracellular growth of Trypanosoma cruzi.
Cell host & microbe 2013;13(1):108-17.
2012: Prerna Bhargava; Lingling Dai; Matthew R Gangl; Donald A Harn; David Jacobi; Changlin Li; Sihao Liu; Kristopher J Stanya; Chih-Hao Lee
Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways.
Nature medicine 2012;18(11):1665-72.
2012: Prerna Bhargava; Chih-Hao Lee
Role and function of macrophages in the metabolic syndrome.
The Biochemical journal 2012;442(2):253-62.
2011: Jessica L Yecies; Hui H Zhang; Suchithra Menon; Derek Yecies; Cem Gorgun; Gökhan S Hotamisligil; David J Kwiatkowski; Chih-Hao Lee; Alex I Lipovsky; Sihao Liu; Brendan D Manning
Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.
Cell metabolism 2011;14(1):21-32.
2011: Sihao Liu; Ben Hatano; Minghui Zhao; Chen-Chung Yen; Kihwa Kang; Shannon M Reilly; Matthew R Gangl; Cem Gorgun; James A Balschi; James M Ntambi; Chih-Hao Lee
Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation.
The Journal of biological chemistry 2011;286(2):1237-47.
2010: Shannon M Reilly; Prerna Bhargava; Sihao Liu; Matthew R Gangl; Cem Gorgun; Russell R Nofsinger; Ronald M Evans; Lu Qi; Frank B Hu; Chih-Hao Lee
Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration.
Cell metabolism 2010;12(6):643-53.
2008: Lu Qi; Kihwa Kang; Cuilin Zhang; Rob van Dam; Peter Kraft; David Hunter; Chih-Hao Lee; Frank B Hu
Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test.
Diabetes 2008;57(11):3145-51.
2008: Kihwa Kang; Shannon M Reilly; volkan karabacak; Matthew R Gangl; Kelly Fitzgerald; Ben Hatano; Chih-Hao Lee
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.
Cell metabolism 2008;7(6):485-95.
2008: Grant D Barish; Annette R Atkins; Michael Downes; Peter Olson; Ling-Wa Chong; Mike Nelson; Yuhua Zou; Hoosang Hwang; H. Kang; Linda Curtiss; Ronald M Evans; Chih-Hao Lee
PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4271-6.
2008: Shannon M Reilly; Chih-Hao Lee
PPAR delta as a therapeutic target in metabolic disease.
FEBS letters 2008;582(1):26-31.
2007: Junichiro Sonoda; Josée Laganière; Isaac R Mehl; Grant D Barish; Ling-Wa Chong; Xiangli Li; Immo E Scheffler; Dennis Mock; Alain R Bataille; François Robert; Chih-Hao Lee; Vincent Giguère; Ronald M Evans
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.
Genes & development 2007;21(15):1909-20.
2006: Chih-Hao Lee; Peter Olson; Andrea L Hevener; Isaac R Mehl; Ling-Wa Chong; Jerrold M Olefsky; Frank J Gonzalez; Jungyeob Ham; H. Kang; Jeffrey M Peters; Ronald M Evans
PPARdelta regulates glucose metabolism and insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3444-9.
2006: Chih-Hao Lee; Kihwa Kang; Isaac R Mehl; Russell Nofsinger; William Alaynick; Ling-Wa Chong; John M Rosenfeld; Ronald M Evans
Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2434-9.
2005: Junichiro Sonoda; Ling-Wa Chong; Michael Downes; Grant D Barish; Sally Coulter; Christopher Liddle; Chih-Hao Lee; Ronald M Evans
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2198-203.
2004: Seung-Hoi Koo; Hiroaki Satoh; Stephan Herzig; Chih-Hao Lee; Susan Hedrick; Rohit Kulkarni; Ronald M Evans; Jerrold M Olefsky; Marc Montminy
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.
Nature medicine 2004;10(5):530-4.
2003: Chih-Hao Lee; Ajay Chawla; Ned Urbiztondo; Debbie Liao; William A Boisvert; Ronald M Evans; Linda K Curtiss
Transcriptional repression of atherogenic inflammation: modulation by PPARdelta.
Science (New York, N.Y.) 2003;302(5644):453-7.
2003: Chih-Hao Lee; Peter Olson; Ronald M Evans
Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors.
Endocrinology 2003;144(6):2201-7.
2003: Yong-Xu Wang; Chih-Hao Lee; Sambath Tiep; Ruth T Yu; Jungyeob Ham; H. Kang; Ronald M Evans
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity.
Cell 2003;113(2):159-70.
2003: Ajay Chawla; Chih-Hao Lee; Yaacov Barak; Weimin He; John Rosenfeld; Debbie Liao; Jungyeob Han; H. Kang; Ronald M Evans
PPARdelta is a very low-density lipoprotein sensor in macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1268-73.
2002: Chih-Hao Lee; Ronald M Evans
Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis.
Trends in endocrinology and metabolism: TEM 2002;13(8):331-5.