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Francisco Baralle

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Chemicals & Drugs

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Molecular Sequence Data

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Publications

TOP 3
Amit Bhardwaj; Emanuele Buratti; Michael P Myers; Francisco E Baralle
Characterizing TDP-43 interaction with its RNA targets.
Emanuele Buratti; Marco Baralle; Francisco E Baralle
From single splicing events to thousands: the ambiguous step forward in splicing research.
S Eréndira Avendaño-Vázquez; Sara Bembich; Emanuele Buratti; Ashish Dhir; Nicholas Proudfoot; Francisco E Baralle
Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.

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All Publications

2013: Amit Bhardwaj; Emanuele Buratti; Michael P Myers; Francisco E Baralle
Characterizing TDP-43 interaction with its RNA targets.
Nucleic acids research 2013;41(9):5062-74.
2013: Emanuele Buratti; Marco Baralle; Francisco E Baralle
From single splicing events to thousands: the ambiguous step forward in splicing research.
Briefings in functional genomics 2013;12(1):3-12.
2012: S Eréndira Avendaño-Vázquez; Sara Bembich; Emanuele Buratti; Ashish Dhir; Nicholas Proudfoot; Francisco E Baralle
Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.
Genes & development 2012;26(15):1679-84.
2012: Lorena Zubović; Marco Baralle; Francisco E Baralle
Mutually exclusive splicing regulates the Nav 1.6 sodium channel function through a combinatorial mechanism that involves three distinct splicing regulatory elements and their ligands.
Nucleic acids research 2012;40(13):6255-69.
2012: Mauricio Budini; Emanuele Buratti; Valentina Romano; S Eréndira Avendaño-Vázquez; Sara Bembich; Francisco E Baralle
Role of selected mutations in the Q/N rich region of TDP-43 in EGFP-12xQ/N-induced aggregate formation.
Brain research 2012;1462():139-50.
2012: Emanuele Buratti; Francisco E Baralle
TDP-43: gumming up neurons through protein-protein and protein-RNA interactions.
Trends in biochemical sciences 2012;37(6):237-47.
2012: Claudia Colombrita; Francesca Megiorni; Elisa Onesto; Antonio Pizzuti; Francisco E Baralle; Emanuele Buratti; Vincenzo Silani; Antonia Ratti
TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells.
The Journal of biological chemistry 2012;287(19):15635-47.
2012: Mauricio Budini; Emanuele Buratti; Laura De Conti; Corrado Guarnaccia; Valentina Romano; Cristiana Stuani; Francisco E Baralle
Cellular model of TAR DNA-binding protein 43 (TDP-43) aggregation based on its C-terminal Gln/Asn-rich region.
The Journal of biological chemistry 2012;287(10):7512-25.
2012: Marija Curlin; Francisco E Baralle; Kamal Chowdhury; Katarina Kapuralin; Andres F Muro; Srećko Gajović
Stam2 expression pattern during embryo development.
Gene expression patterns : GEP 2012;12(1-2):68-76.
2011: Francisco E Baralle; Emanuele Buratti
TDP-43: Overview of the series.
The FEBS journal 2011;278(19):3529.
2011: Emanuele Buratti; Francisco E Baralle
TDP-43: new aspects of autoregulation mechanisms in RNA binding proteins and their connection with human disease.
The FEBS journal 2011;278(19):3530-8.
2011: Paola Zago; Emanuele Buratti; Cristiana Stuani; Francisco E Baralle
Evolutionary connections between coding and splicing regulatory regions in the fibronectin EDA exon.
Journal of molecular biology 2011;411(1):1-15.
2011: M Budini; Francisco E Baralle; Emanuele Buratti
Regulation of gene expression by TDP-43 and FUS/TLS in frontotemporal lobar degeneration.
Current Alzheimer research 2011;8(3):237-45.
2011: Youhna M Ayala; Laura De Conti; S Eréndira Avendaño-Vázquez; Ashish Dhir; Maurizio Romano; Andrea D'Ambrogio; James Tollervey; Jernej Ule; Marco Baralle; Emanuele Buratti; Francisco E Baralle
TDP-43 regulates its mRNA levels through a negative feedback loop.
The EMBO journal 2011;30(2):277-88.
2011: Vinay K Godena; Giulia Romano; Maurizio Romano; Chiara Appocher; Raffaella Klima; Emanuele Buratti; Francisco E Baralle; Fabian Feiguin
TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization.
PloS one 2011;6(3):e17808.
2010: Emanuele Buratti; Francisco E Baralle
Neurons don't appreciate FUSsing in the cytoplasm.
The EMBO journal 2010;29(16):2769-71.
2010: Ashish Dhir; Emanuele Buratti; Maria A van Santen; Reinhard Lührmann; Francisco E Baralle
The intronic splicing code: multiple factors involved in ATM pseudoexon definition.
The EMBO journal 2010;29(4):749-60.
2010: Ariful Haque; Emanuele Buratti; Francisco E Baralle
Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12.
Nucleic acids research 2010;38(2):647-59.
2009: Francisco E Baralle
Italy leads the way in supporting African biotechnology.
Nature 2009;460(7259):1079.
2009: Andrea D'Ambrogio; Emanuele Buratti; Cristiana Stuani; Corrado Guarnaccia; Maurizio Romano; Youhna M Ayala; Francisco E Baralle
Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo.
Nucleic acids research 2009;37(12):4116-26.
2009: Fabian Feiguin; Vinay K Godena; Giulia Romano; Andrea D'Ambrogio; Raffaella Klima; Francisco E Baralle
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior.
FEBS letters 2009;583(10):1586-92.
2009: Roberto Marcucci; Maurizio Romano; Fabian Feiguin; Mary A O'Connell; Francisco E Baralle
Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR.
Nucleic acids research 2009;37(5):1663-71.
2009: Takashi Nonaka; Tetsuaki Arai; Emanuele Buratti; Francisco E Baralle; Haruhiko Akiyama; Masato Hasegawa
Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.
FEBS letters 2009;583(2):394-400.
2009: Emanuele Buratti; Francisco E Baralle
The molecular links between TDP-43 dysfunction and neurodegeneration.
Advances in genetics 2009;66():1-34.
2008: Youhna M Ayala; Paola Zago; Andrea D'Ambrogio; Ya-Fei Xu; Leonard Petrucelli; Emanuele Buratti; Francisco E Baralle
Structural determinants of the cellular localization and shuttling of TDP-43.
Journal of cell science 2008;121(Pt 22):3778-85.
2008: Yuki Inukai; Takashi Nonaka; Tetsuaki Arai; Mari Yoshida; Yoshio Hashizume; Thomas Beach; Emanuele Buratti; Francisco E Baralle; Haruhiko Akiyama; Shin-ichi Hisanaga; Masato Hasegawa
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.
FEBS letters 2008;582(19):2899-904.
2008: Marco Baralle; Francisco E Baralle
Genetics and molecular biology: variations in alternative spliced pre-mRNA-protein isoforms and their role in disease.
Current opinion in lipidology 2008;19(4):429-30.
2008: Natasa Skoko; Marco Baralle; Emanuele Buratti; Francisco E Baralle
The pathological splicing mutation c.6792C>G in NF1 exon 37 causes a change of tenancy between antagonistic splicing factors.
FEBS letters 2008;582(15):2231-6.
2008: Vladimir R Babaev; Fabiola Porro; MacRae F Linton; Sergio Fazio; Francisco E Baralle; Andrés F Muro
Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice.
Atherosclerosis 2008;197(2):534-40.
2008: Andrés F Muro; Federico A Moretti; Bethany B Moore; Mei Yan; Rachelle G Atrasz; Carol A Wilke; Kevin R Flaherty; Fernando J Martinez; Jessica L Tsui; Dean Sheppard; Francisco E Baralle; Galen Toews; Eric White
An essential role for fibronectin extra type III domain A in pulmonary fibrosis.
American journal of respiratory and critical care medicine 2008;177(6):638-45.
2008: Youhna M Ayala; Tom Misteli; Francisco E Baralle
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3785-9.
2008: Maurizio Romano; Maria Giulia Bacalini; Ernst J Verschoor; Sergio Crovella; Francisco E Baralle
Origin and evolution of the c.844_845ins68/c.833T>C mutations within the cystathionine beta-synthase gene in great apes.
FEBS letters 2008;582(3):423-6.
2008: Anil K Chauhan; Janka Kisucka; Maria R Cozzi; Meghan T Walsh; Federico A Moretti; Monica Battiston; Mario Mazzucato; Luigi De Marco; Francisco E Baralle; Denisa D Wagner; Andrés F Muro
Prothrombotic effects of fibronectin isoforms containing the EDA domain.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(2):296-301.
2008: Emanuele Buratti; Francisco E Baralle
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease.
Frontiers in bioscience : a journal and virtual library 2008;13():867-78.
2007: Federico A Moretti; Anil K Chauhan; Alessandra Iaconcig; Fabiola Porro; Francisco E Baralle; Andrés F Muro
A major fraction of fibronectin present in the extracellular matrix of tissues is plasma-derived.
The Journal of biological chemistry 2007;282(38):28057-62.
2007: Matthieu Giraud; Richard Taubert; Claire Vandiedonck; Xiayi Ke; Matthieu Lévi-Strauss; Franco Pagani; Francisco E Baralle; Bruno Eymard; Christine Tranchant; Philippe Gajdos; Angela Vincent; Nick Willcox; David Beeson; Bruno Kyewski; Henri-Jean Garchon
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus.
Nature 2007;448(7156):934-7.
2007: Marco Baralle; Francisco E Baralle
Genetics and molecular biology: micro RNAs are welcome to the lipid field.
Current opinion in lipidology 2007;18(3):375-7.
2007: Emanuele Buratti; Ashish Dhir; Marzena A Lewandowska; Francisco E Baralle
RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events.
Nucleic acids research 2007;35(13):4369-83.
2007: Emanuele Buratti; Cristiana Stuani; Greta De Prato; Francisco E Baralle
SR protein-mediated inhibition of CFTR exon 9 inclusion: molecular characterization of the intronic splicing silencer.
Nucleic acids research 2007;35(13):4359-68.
2007: Michela Raponi; Francisco E Baralle; Franco Pagani
Reduced splicing efficiency induced by synonymous substitutions may generate a substrate for natural selection of new splicing isoforms: the case of CFTR exon 12.
Nucleic acids research 2007;35(2):606-13.
2007: Roberto Marcucci; Francisco E Baralle; Maurizio Romano
Complex splicing control of the human Thrombopoietin gene by intronic G runs.
Nucleic acids research 2007;35(1):132-42.
2006: Marco Baralle; Natasa Skoko; Anna Knezevich; Laura De Conti; Dario Motti; Madhuri Bhuvanagiri; Diana Baralle; Emanuele Buratti; Francisco E Baralle
NF1 mRNA biogenesis: effect of the genomic milieu in splicing regulation of the NF1 exon 37 region.
FEBS letters 2006;580(18):4449-56.
2006: Marco Baralle; Francisco E Baralle
Genetics and molecular biology: single nucleotide polymorphism associations and their functional significance.
Current opinion in lipidology 2006;17(3):360-2.
2006: Youhna M Ayala; Franco Pagani; Francisco E Baralle
TDP43 depletion rescues aberrant CFTR exon 9 skipping.
FEBS letters 2006;580(5):1339-44.
2006: Emanuele Buratti; Marco Baralle; Francisco E Baralle
Defective splicing, disease and therapy: searching for master checkpoints in exon definition.
Nucleic acids research 2006;34(12):3494-510.
2006: Luisa Costessi; Giulia Devescovi; Francisco E Baralle; Andrés F Muro
Brain-specific promoter and polyadenylation sites of the beta-adducin pre-mRNA generate an unusually long 3'-UTR.
Nucleic acids research 2006;34(1):243-53.
2005: Emanuele Buratti; Antonia Brindisi; Maurizio Giombi; Sergio Tisminetzky; Youhna M Ayala; Francisco E Baralle
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing.
The Journal of biological chemistry 2005;280(45):37572-84.
2005: Juan Pablo Fededa; Ezequiel Petrillo; Mikhail S Gelfand; Alexei D Neverov; Sebastián Kadener; Guadalupe Nogués; Federico Pelisch; Francisco E Baralle; Andrés F Muro; Alberto R Kornblihtt
A polar mechanism coordinates different regions of alternative splicing within a single gene.
Molecular cell 2005;19(3):393-404.
2005: Michela Zanetti; Rocco Barazzoni; Marco Stebel; Elena Roder; Gianni Biolo; Francisco E Baralle; Luigi Cattin; Gianfranco Guarnieri
Dysregulation of the endothelial nitric oxide synthase-soluble guanylate cyclase pathway is normalized by insulin in the aorta of diabetic rat.
Atherosclerosis 2005;181(1):69-73.
2005: Anil K Chauhan; Federico Andrea Moretti; Alessandra Iaconcig; Francisco E Baralle; Andrés F Muro
Impaired motor coordination in mice lacking the EDA exon of the fibronectin gene.
Behavioural brain research 2005;161(1):31-8.
2005: Marco Baralle; Francisco E Baralle
Genetics and molecular biology.
Current opinion in lipidology 2005;16(3):385-7.
2005: Youhna M Ayala; Sergio Pantano; Andrea D'Ambrogio; Emanuele Buratti; Antonia Brindisi; Caterina Marchetti; Maurizio Romano; Francisco E Baralle
Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function.
Journal of molecular biology 2005;348(3):575-88.
2005: Franco Pagani; Michela Raponi; Francisco E Baralle
Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(18):6368-72.
2005: Pablo Arrisi Mercado; Youhna M Ayala; Maurizio Romano; Emanuele Buratti; Francisco E Baralle
Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.
Nucleic acids research 2005;33(18):6000-10.
2005: Marzena A Lewandowska; Cristiana Stuani; Alireza Parvizpur; Francisco E Baralle; Franco Pagani
Functional studies on the ATM intronic splicing processing element.
Nucleic acids research 2005;33(13):4007-15.
2005: Emanuele Buratti; Francisco E Baralle
Another step forward for SELEXive splicing.
Trends in molecular medicine 2005;11(1):5-9.
2004: Emanuele Buratti; Francisco E Baralle
Influence of RNA secondary structure on the pre-mRNA splicing process.
Molecular and cellular biology 2004;24(24):10505-14.
2004: Fabiola Porro; Luisa Costessi; Martín L Marro; Francisco E Baralle; Andrés F Muro
The erythrocyte skeletons of beta-adducin deficient mice have altered levels of tropomyosin, tropomodulin and EcapZ.
FEBS letters 2004;576(1-2):36-40.
2004: Caterina Marchetti; Pierluigi Patriarca; G Pietro Solero; Francisco E Baralle; Maurizio Romano
Genetic studies on myeloperoxidase deficiency in Italy.
Japanese journal of infectious diseases 2004;57(5):S10-2.
2004: Pablo Arrisi-Mercado; Maurizio Romano; Andrés F Muro; Francisco E Baralle
An exonic splicing enhancer offsets the atypical GU-rich 3' splice site of human apolipoprotein A-II exon 3.
The Journal of biological chemistry 2004;279(38):39331-9.
2004: Li Zhang; G Michael Vincent; Marco Baralle; Francisco E Baralle; Blake D Anson; D Woodrow Benson; Bryant Whiting; Katherine W Timothy; John F Carlquist; Craig T January; Mark T Keating; Igor Splawski
An intronic mutation causes long QT syndrome.
Journal of the American College of Cardiology 2004;44(6):1283-91.
2004: Mario C O Probst; Harald Thumann; Charalampos Aslanidis; Thomas Langmann; Christa Buechler; Wolfgang Patsch; Francisco E Baralle; Geesje M Dallinga-Thie; Jürgen Geisel; Christiane Keller; Valentine C Menys; Gerd Schmitz
Screening for functional sequence variations and mutations in ABCA1.
Atherosclerosis 2004;175(2):269-79.
2004: Marco Baralle; Francisco E Baralle
Vascular gene therapy: getting to know the players, avoiding the pitfalls.
Current opinion in lipidology 2004;15(4):479-81.
2004: Emanuele Buratti; Antonia Brindisi; Franco Pagani; Francisco E Baralle
Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of exon 9: a functional link with disease penetrance.
American journal of human genetics 2004;74(6):1322-5.
2004: Franco Pagani; Francisco E Baralle
Genomic variants in exons and introns: identifying the splicing spoilers.
Nature reviews. Genetics 2004;5(5):389-96.
2004: Caterina Marchetti; Pierluigi Patriarca; G Pietro Solero; Francisco E Baralle; Maurizio Romano
Genetic characterization of myeloperoxidase deficiency in Italy.
Human mutation 2004;23(5):496-505.
2004: Elisabetta Zuccato; Emanuele Buratti; Cristiana Stuani; Francisco E Baralle; Franco Pagani
An intronic polypyrimidine-rich element downstream of the donor site modulates cystic fibrosis transmembrane conductance regulator exon 9 alternative splicing.
The Journal of biological chemistry 2004;279(17):16980-8.
2004: Emanuele Buratti; Andrés F Muro; Maurizio Giombi; Daniel Gherbassi; Alessandra Iaconcig; Francisco E Baralle
RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.
Molecular and cellular biology 2004;24(3):1387-400.
2004: Anil K Chauhan; Alessandra Iaconcig; Francisco E Baralle; Andrés F Muro
Alternative splicing of fibronectin: a mouse model demonstrates the identity of in vitro and in vivo systems and the processing autonomy of regulated exons in adult mice.
Gene 2004;324():55-63.
2004: Emanuele Buratti; Marco Baralle; Laura De Conti; Diana Baralle; Maurizio Romano; Youhna M Ayala; Francisco E Baralle
hnRNP H binding at the 5' splice site correlates with the pathological effect of two intronic mutations in the NF-1 and TSHbeta genes.
Nucleic acids research 2004;32(14):4224-36.
2003: Franco Pagani; Emanuele Buratti; Cristiana Stuani; Francisco E Baralle
Missense, nonsense, and neutral mutations define juxtaposed regulatory elements of splicing in cystic fibrosis transmembrane regulator exon 9.
The Journal of biological chemistry 2003;278(29):26580-8.
2003: Andrés F Muro; Anil K Chauhan; Srecko Gajovic; Alessandra Iaconcig; Fabiola Porro; Giorgio Stanta; Francisco E Baralle
Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan.
The Journal of cell biology 2003;162(1):149-60.
2003: Emanuele Buratti; Francisco E Baralle; Franco Pagani
Can a 'patch' in a skipped exon make the pre-mRNA splicing machine run better?
Trends in molecular medicine 2003;9(6):229-32; discussion 233-4.
2003: Franco Pagani; Cristiana Stuani; Maria Tzetis; Emmanuel Kanavakis; Alexandra Efthymiadou; Stavros Doudounakis; Teresa Casals; Francisco E Baralle
New type of disease causing mutations: the example of the composite exonic regulatory elements of splicing in CFTR exon 12.
Human molecular genetics 2003;12(10):1111-20.
2003: Marco Baralle; Diana Baralle; Laura De Conti; Chris Mattocks; Joanne Whittaker; A Knezevich; Charles ffrench-Constant; Francisco E Baralle
Identification of a mutation that perturbs NF1 agene splicing using genomic DNA samples and a minigene assay.
Journal of medical genetics 2003;40(3):220-2.
2003: Daniel Portal; Joaquín M Espinosa; Guillermo Lobo; Sebastián Kadener; Claudio Alejandro Pereira; Manuel De La Mata; Zhaohua Tang; Ren-Jang Lin; Alberto R Kornblihtt; Francisco E Baralle; Mirtha M Flawiá; Héctor N Torres
An early ancestor in the evolution of splicing: a Trypanosoma cruzi serine-arginine-rich protein (TcSR) is functional in cis-splicing.
Molecular and biochemical parasitology 2003;127(1):37-46.
2003: Franco Pagani; Cristiana Stuani; Elisabetta Zuccato; Alberto R Kornblihtt; Francisco E Baralle
Promoter architecture modulates CFTR exon 9 skipping.
The Journal of biological chemistry 2003;278(3):1511-7.
2002: Maurizio Romano; Roberto Marcucci; Emanuele Buratti; Youhna M Ayala; Gianfranco Sebastio; Francisco E Baralle
Regulation of 3' splice site selection in the 844ins68 polymorphism of the cystathionine Beta -synthase gene.
The Journal of biological chemistry 2002;277(46):43821-9.
2002: Franco Pagani; Emanuele Buratti; Cristiana Stuani; Regina Bendix; Thilo Dörk; Francisco E Baralle
A new type of mutation causes a splicing defect in ATM.
Nature genetics 2002;30(4):426-9.
2001: Marco Baralle; Francisco E Baralle
Genetics and molecular biology.
Current opinion in lipidology 2001;12(6):663-5.
2001: F Odreman-Macchioli; Francisco E Baralle; Emanuele Buratti
Mutational analysis of the different bulge regions of hepatitis C virus domain II and their influence on internal ribosome entry site translational ability.
The Journal of biological chemistry 2001;276(45):41648-55.
2001: Emanuele Buratti; Francisco E Baralle
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9.
The Journal of biological chemistry 2001;276(39):36337-43.
2001: Juan Fló; Sergio Tisminetzky; Francisco E Baralle
Codelivery of DNA coding for the soluble form of CD86 results in the down-regulation of the immune response to DNA vaccines.
Cellular immunology 2001;209(2):120-31.
2001: Emanuele Buratti; Thilo Dörk; Elisabetta Zuccato; Franco Pagani; Maurizio Romano; Francisco E Baralle
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.
The EMBO journal 2001;20(7):1774-84.
2001: Maurizio Romano; Roberto Marcucci; Francisco E Baralle
Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene.
Nucleic acids research 2001;29(4):886-94.
2001: Juan Fló; Sergio Tisminetzky; Francisco E Baralle
Oral transgene vaccination mediated by attenuated Salmonellae is an effective method to prevent Herpes simplex virus-2 induced disease in mice.
Vaccine 2001;19(13-14):1772-82.
2000: Marco Baralle; Francisco E Baralle
Genetics and molecular biology.
Current opinion in lipidology 2000;11(6):653-6.
2000: Martín L Marro; Oscar Scremin; Maria C Jordan; L Huynh; Fabiola Porro; Kenneth P Roos; Srecko Gajovic; Francisco E Baralle; Andrés F Muro
Hypertension in beta-adducin-deficient mice.
Hypertension 2000;36(3):449-53.
2000: Juan Fló; A Beatriz Perez; Sergio Tisminetzky; Francisco E Baralle
Superiority of intramuscular route and full length glycoprotein D for DNA vaccination against herpes simplex 2. Enhancement of protection by the co-delivery of the GM-CSF gene.
Vaccine 2000;18(28):3242-53.
2000: Franco Pagani; Emanuele Buratti; Cristiana Stuani; Maurizio Romano; Elisabetta Zuccato; M Niksic; Luisella Giglio; Dino Faraguna; Francisco E Baralle
Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element.
The Journal of biological chemistry 2000;275(28):21041-7.
2000: Andrés F Muro; Martín L Marro; S Gajović; Fabiola Porro; L Luzzatto; Francisco E Baralle
Mild spherocytic hereditary elliptocytosis and altered levels of alpha- and gamma-adducins in beta-adducin-deficient mice.
Blood 2000;95(12):3978-85.
2000: Juan Fló; Sergio Tisminetzky; Francisco E Baralle
Modulation of the immune response to DNA vaccine by co-delivery of costimulatory molecules.
Immunology 2000;100(2):259-67.
2000: Maurizio Romano; Francisco E Baralle; Pierluigi Patriarca
Expression and characterization of recombinant human eosinophil peroxidase. Impact of the R286H substitution on the biosynthesis and activity of the enzyme.
European journal of biochemistry / FEBS 2000;267(12):3704-11.
2000: Giorgio Stanta; Lory Saveria Crocè; Serena Bonin; Sergio Tisminetzky; Francisco E Baralle; Claudio Tiribelli
Cohort effect of HCV infection in liver cirrhosis assessed by a 25 year study.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2000;17(1):51-6.
2000: F E Odreman-Macchioli; Sergio Tisminetzky; M Zotti; Francisco E Baralle; Emanuele Buratti
Influence of correct secondary and tertiary RNA folding on the binding of cellular factors to the HCV IRES.
Nucleic acids research 2000;28(4):875-85.
2000: S Matthew Cleveland; Emanuele Buratti; Tim D Jones; P North; Francisco E Baralle; Lesley McLain; TL McInerney; Z Durrani; Nigel J Dimmock
Immunogenic and antigenic dominance of a nonneutralizing epitope over a highly conserved neutralizing epitope in the gp41 envelope glycoprotein of human immunodeficiency virus type 1: its deletion leads to a strong neutralizing response.
Virology 2000;266(1):66-78.
1999: M Niksic; M Romano; Emanuele Buratti; Franco Pagani; Francisco E Baralle
Functional analysis of cis-acting elements regulating the alternative splicing of human CFTR exon 9.
Human molecular genetics 1999;8(13):2339-49.
1999: Giorgio Stanta; Serena Bonin; Benedetta Niccolini; A Raccanelli; Francisco E Baralle
Catalytic subunit of telomerase expression is related to RNA component expression.
FEBS letters 1999;460(2):285-8.
1999: Laurent Vergnes; Nadine Baroukh; T Léhy; Laurent Moizo; André Bado; Marco Baralle; Francisco E Baralle; Mario M Zakin; Alberto Ochoa
Human apolipoprotein A-IV reduces gastric acid secretion and diminishes ulcer formation in transgenic mice.
FEBS letters 1999;460(1):178-81.
1999: C Gustavo Pesce; Guadalupe Nogués; Claudio R Alonso; Francisco E Baralle; Alberto R Kornblihtt
Interaction between the (-170) CRE and the (-150) CCAAT box is necessaryfor efficient activation of the fibronectin gene promoter by cAMP and ATF-2.
FEBS letters 1999;457(3):445-51.
1999: Paula Cramer; Javier F Cáceres; Demian Cazalla; Sebastián Kadener; Andrés F Muro; Francisco E Baralle; Alberto R Kornblihtt
Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer.
Molecular cell 1999;4(2):251-8.
1999: Marco Baralle; Francisco E Baralle
Genetics and molecular biology.
Current opinion in lipidology 1999;10(4):365-8.
1999: C Vandelli; F Renzo; H B Braun; Sergio Tisminetzky; M Albrecht; M De Palma; A Ranzi; G Di Marco; Tommaso Stroffolini; Francisco E Baralle; E Ventura; G Michel
Prediction of successful outcome in a randomised controlled trial of the long-term efficacy of interferon alpha treatment for chronic hepatitis C.
Journal of medical virology 1999;58(1):26-34.
1999: Andrés F Muro; M Caputi; R Pariyarath; Franco Pagani; Emanuele Buratti; Francisco E Baralle
Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display.
Molecular and cellular biology 1999;19(4):2657-71.
1999: Marco Baralle; Laurent Vergnes; A F Muro; Mario M Zakin; Francisco E Baralle; Alberto Ochoa
Regulation of the human apolipoprotein AIV gene expression in transgenic mice.
FEBS letters 1999;445(1):45-52.
1998: Emanuele Buratti; Lesley McLain; Sergio Tisminetzky; S Matthew Cleveland; Nigel J Dimmock; Francisco E Baralle
The neutralizing antibody response against a conserved region of human immunodeficiency virus type 1 gp41 (amino acid residues 731-752) is uniquely directed against a conformational epitope.
The Journal of general virology 1998;79 ( Pt 11)():2709-16.
1998: Andrés F Muro; Alessandra Iaconcig; Francisco E Baralle
Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5' splicing site.
FEBS letters 1998;437(1-2):137-41.
1998: Alejandro J Urtreger; Fabiola Porro; Lydia Puricelli; Santiago E Werbajh; Francisco E Baralle; Elisa Bal de Kier Joffé; Alberto R Kornblihtt; Andrés F Muro
Expression of RGD minus fibronectin that does not form extracellular matrix fibrils is sufficient to decrease tumor metastasis.
International journal of cancer. Journal international du cancer 1998;78(2):233-41.
1998: Franco Pagani; R Pariyarath; R Garcia; Cristiana Stuani; A B Burlina; Giacomo Ruotolo; M Rabusin; Francisco E Baralle
New lysosomal acid lipase gene mutants explain the phenotype of Wolman disease and cholesteryl ester storage disease.
Journal of lipid research 1998;39(7):1382-8.
1998: Emanuele Buratti; Sergio Tisminetzky; M Zotti; Francisco E Baralle
Functional analysis of the interaction between HCV 5'UTR and putative subunits of eukaryotic translation initiation factor eIF3.
Nucleic acids research 1998;26(13):3179-87.
1998: G M Danek; M Valenti; Francisco E Baralle; M Romano
The A/G polymorphism in the -78 position of the apolipoprotein A-I promoter does not have a direct effect on transcriptional efficiency.
Biochimica et biophysica acta 1998;1398(1):67-74.
1998: Emanuele Buratti; Francisco E Baralle; Sergio Tisminetzky
Localization of the different hepatitis C virus core gene products expressed in COS-1 cells.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(3):505-12.
1998: Mario Pirisi; Pierluigi Toniutto; Carlo Fabris; T Lombardelli; Edmondo Falleti; Sergio Tisminetzky; Francisco E Baralle; Ettore G Bartoli
Factors associated with serum HCV RNA positivity in anti-HCV antibody positive intravenous drug users.
Journal of clinical epidemiology 1998;51(5):423-7.
1998: Pierluigi Toniutto; Mario Pirisi; Carlo Fabris; P Bardus; Giorgio Soardo; D Vitulli; Sergio Tisminetzky; P Pacco; V Gasparini; Francisco E Baralle; Ettore G Bartoli
High prevalence of infection with hepatitis G virus in patients with hepatic and extrahepatic malignancies.
Journal of hepatology 1998;28(4):550-5.
1997: Maurizio Romano; Pietro Dri; L Dadalt; Pierluigi Patriarca; Francisco E Baralle
Biochemical and molecular characterization of hereditary myeloperoxidase deficiency.
Blood 1997;90(10):4126-34.
1997: Paula Cramer; C Gustavo Pesce; Francisco E Baralle; Alberto R Kornblihtt
Functional association between promoter structure and transcript alternative splicing.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11456-60.
1997: Franco Pagani; R Pariyarath; Cristiana Stuani; R Garcia; Francisco E Baralle
Cysteine residues in human lysosomal acid lipase are involved in selective cholesteryl esterase activity.
The Biochemical journal 1997;326 ( Pt 1)():265-9.
1997: Emanuele Buratti; Martina Gerotto; Patrizia Pontisso; Alfredo Alberti; Sergio Tisminetzky; Francisco E Baralle
In vivo translational efficiency of different hepatitis C virus 5'-UTRs.
FEBS letters 1997;411(2-3):275-80.
1997: Mario Pirisi; Carlo Fabris; Pierluigi Toniutto; Edmondo Falleti; Sergio Tisminetzky; Martina Gerotto; Giorgio Soardo; D Vitulli; Monica Del Forno; Francisco E Baralle; Ettore G Bartoli
Endogenous interferon-alpha concentration and outcome of interferon treatment in patients with chronic hepatitis C.
Digestive diseases and sciences 1997;42(4):767-71.
1997: Emanuele Buratti; M Di Michele; P Song; C Monti-Bragadin; E A Scodeller; Francisco E Baralle; Sergio Tisminetzky
Improved reactivity of hepatitis C virus core protein epitopes in a conformational antigen-presenting system.
Clinical and diagnostic laboratory immunology 1997;4(2):117-21.
1997: Emanuele Buratti; Sergio Tisminetzky; P D'Agaro; Francisco E Baralle
A neutralizing monoclonal antibody previously mapped exclusively on human immunodeficiency virus type 1 gp41 recognizes an epitope in p17 sharing the core sequence IEEE.
Journal of virology 1997;71(3):2457-62.
1997: Luigi Cattin; Francisco E Baralle
Genetics and molecular biology.
Current opinion in lipidology 1997;8(1):U4-5.
1997: M Schiappacassi; Emanuele Buratti; P D'Agaro; L Ciani; E S Scodeller; Sergio Tisminetzky; Francisco E Baralle
V3 loop core region serotyping of HIV-1 infected patients using the FHV epitope presenting system.
Journal of virological methods 1997;63(1-2):121-7.
1997: Luigi Cattin; Maurizio Fisicaro; M Tonizzo; M Valenti; G M Danek; Maurizio Fonda; P G Da Col; S Casagrande; E Pincetri; Massimo Bovenzi; Francisco E Baralle
Polymorphism of the apolipoprotein E gene and early carotid atherosclerosis defined by ultrasonography in asymptomatic adults.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(1):91-4.
1996: R Pariyarath; Franco Pagani; Cristiana Stuani; R Garcia; Francisco E Baralle
L273S missense substitution in human lysosomal acid lipase creates a new N-glycosylation site.
FEBS letters 1996;397(1):79-82.
1996: Emanuele Buratti; Sergio Tisminetzky; E S Scodeller; Francisco E Baralle
Conformational display of two neutralizing epitopes of HIV-1 gp41 on the Flock House virus capsid protein.
Journal of immunological methods 1996;197(1-2):7-18.
1996: Franco Pagani; R Garcia; R Pariyarath; Cristiana Stuani; Bruno Gridelli; G Paone; Francisco E Baralle
Expression of lysosomal acid lipase mutants detected in three patients with cholesteryl ester storage disease.
Human molecular genetics 1996;5(10):1611-7.
1996: Pierluigi Toniutto; Mario Pirisi; Sergio Tisminetzky; C Fabris; E Chinellato; Martina Gerotto; Edmondo Falleti; P Ferroni; T Lombardelli; Ettore G Bartoli; Francisco E Baralle
Discordant results from hepatitis C virus genotyping by procedures based on amplification of different genomic regions.
Journal of clinical microbiology 1996;34(10):2382-5.
1995: Sergio Tisminetzky; G Devescovi; Grazia Tripodi; A Muro; Giuseppe Bianchi; M Colombi; L Moro; Sergio Barlati; Renu Tuteja; Francisco E Baralle
Genomic organisation and chromosomal localisation of the gene encoding human beta adducin.
Gene 1995;167(1-2):313-6.
1995: Grazia Tripodi; Giorgio Casari; Sergio Tisminetzky; Giuseppe Bianchi; G Devescovi; A Muro; Renu Tuteja; Francisco E Baralle
Characterisation and chromosomal localisation of the rat alpha- and beta-adducin-encoding genes.
Gene 1995;166(2):307-11.
1995: Sergio Tisminetzky; Martina Gerotto; Patrizia Pontisso; Liliana Chemello; L E Prescott; K A Rose; Francisco E Baralle; P Simmonds; Alfredo Alberti
Comparison of genotyping and serotyping methods for the identification of hepatitis C virus types.
Journal of virological methods 1995;55(3):303-7.
1995: E A Scodeller; Sergio Tisminetzky; F Porro; M Schiappacassi; A De Rossi; L Chiecco-Bianchi; Francisco E Baralle
A new epitope presenting system displays a HIV-1 V3 loop sequence and induces neutralizing antibodies.
Vaccine 1995;13(13):1233-9.
1995: M Caputi; Francisco E Baralle; C A Melo
Analysis of the linkage between fibronectin alternative spliced sites during ageing in rat tissues.
Biochimica et biophysica acta 1995;1263(1):53-9.
1995: M Caputi; C A Melo; Francisco E Baralle
Regulation of fibronectin expression in rat regenerating liver.
Nucleic acids research 1995;23(2):238-43.
1994: Bruno Bembi; M Zanatta; M Carrozzi; Francisco E Baralle; Rosalba Gornati; Bruno Berra; E Agosti
Enzyme replacement treatment in type 1 and type 3 Gaucher's disease.
Lancet 1994;344(8938):1679-82.
1994: Renu Tuteja; Narendra Tuteja; F Lilliu; Bruno Bembi; R Galanello; A Cao; Francisco E Baralle
Y418C: a novel mutation in exon 9 of the glucocerebrosidase gene of a patient with Gaucher disease creates a new Bgl I site.
Human genetics 1994;94(3):314-5.
1994: M Caputi; Giorgio Casari; S Guenzi; R Tagliabue; A Sidoli; C A Melo; Francisco E Baralle
A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon.
Nucleic acids research 1994;22(6):1018-22.
1993: C A Melo; C Serra; V Stoyanova; C Aguzzoli; D Faraguna; A Tamanini; Giorgio Berton; Giulio Cabrini; Francisco E Baralle
Alternative splicing of a previously unidentified CFTR exon introduces an in-frame stop codon 5' of the R region.
FEBS letters 1993;329(1-2):159-62.
1993: Renu Tuteja; Bruno Bembi; E Agosti; Francisco E Baralle
1448C mutation linked to the Pv1.1- genotype in Italian patients with Gaucher disease.
Human molecular genetics 1993;2(6):781-4.
1992: Renu Tuteja; Narendra Tuteja; C Melo; Giorgio Casari; Francisco E Baralle
Transcription efficiency of human apolipoprotein A-I promoter varies with naturally occurring A to G transition.
FEBS letters 1992;304(1):98-101.
1991: Vincenzo Silani; Antonio Pizzuti; Andrea Falini; Giuseppe Borsani; Elena I Rugarli; C A Melo; A Sidoli; F Villani; Francisco E Baralle; Guglielmo Scarlato
Beta-nerve growth factor (beta-NGF) mRNA expression in the parkinsonian adrenal gland.
Experimental neurology 1991;113(2):166-70.
1991: Andrea Falini; Vincenzo Silani; Antonio Pizzuti; Elena I Rugarli; D Mariani; R Bassani; A Vegeto; Francisco E Baralle; Guglielmo Scarlato
Maintained cellular function of adrenal medullary cells in parkinsonian dysautonomia.
Functional neurology 1991;6(3):259-61.
1991: Grazia Tripodi; A Piscone; Giuseppe Borsani; Sergio Tisminetzky; S Salardi; A Sidoli; P James; Sandor Pongor; G Bianchi; Francisco E Baralle
Molecular cloning of an adducin-like protein: evidence of a polymorphism in the normotensive and hypertensive rats of the Milan strain.
Biochemical and biophysical research communications 1991;177(3):939-47.
1991: Giuseppe Borsani; Antonio Pizzuti; Elena I Rugarli; Andrea Falini; Guglielmo Scarlato; Francisco E Baralle; Vincenzo Silani
Human fetal brain beta-nerve growth factor cDNA: molecular cloning of 5' and 3' untranslated regions.
Neuroscience letters 1991;127(1):117-20.
1991: Franco Pagani; Laura Zagato; Carlo Vergani; Giorgio Casari; A Sidoli; Francisco E Baralle
Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat.
The Journal of cell biology 1991;113(5):1223-9.
1990: Franco Pagani; A Sidoli; G A Giudici; L Barenghi; Carlo Vergani; Francisco E Baralle
Human apolipoprotein A-I gene promoter polymorphism: association with hyperalphalipoproteinemia.
Journal of lipid research 1990;31(8):1371-7.
1990: Giuseppe Borsani; Antonio Pizzuti; Elena I Rugarli; Andrea Falini; Vincenzo Silani; A Sidoli; Guglielmo Scarlato; Francisco E Baralle
cDNA sequence of human beta-NGF.
Nucleic acids research 1990;18(13):4020.
1990: Antonio Pizzuti; Giuseppe Borsani; Andrea Falini; Elena I Rugarli; A Sidoli; Francisco E Baralle; Guglielmo Scarlato; Vincenzo Silani
Detection of beta-nerve growth factor mRNA in the human fetal brain.
Brain research 1990;518(1-2):337-41.
1989: C C Shoulders; M J Ball; Francisco E Baralle
Variation in the apo AI/CIII/AIV gene complex: its association with hyperlipidemia.
Atherosclerosis 1989;80(2):111-8.
1989: S Salardi; maria beatrice saccardo; Giuseppe Borsani; R Modica; Mara Ferrandi; M G Tripodi; Marco Soria; Patrizia Ferrari; Francisco E Baralle; A Sidoli
Erythrocyte adducin differential properties in the normotensive and hypertensive rats of the Milan strain. Characterization of spleen adducin m-RNA.
American journal of hypertension 1989;2(4):229-37.
1989: M V Barone; C Henchcliffe; Francisco E Baralle; G Paolella
Cell type specific trans-acting factors are involved in alternative splicing of human fibronectin pre-mRNA.
The EMBO journal 1989;8(4):1079-85.
1989: M A Lucero; D Sanchez; Alberto Ochoa; F Brunel; G N Cohen; Francisco E Baralle; Mario M Zakin
Interaction of DNA-binding proteins with the tissue-specific human apolipoprotein-AII enhancer.
Nucleic acids research 1989;17(6):2283-300.
1988: G Paolella; C Henchcliffe; G Sebastio; Francisco E Baralle
Sequence analysis and in vivo expression show that alternative splicing of ED-B and ED-A regions of the human fibronectin gene are independent events.
Nucleic acids research 1988;16(8):3545-57.
1988: K Jenner; A Sidoli; M Ball; J R Rodriguez; Franco Pagani; G Giudici; Carlo Vergani; J Mann; Francisco E Baralle; C C Shoulders
Characterization of genetic markers in the 3' end of the apo B gene and their use in family and population studies.
Atherosclerosis 1988;69(1):39-49.
1987: Helen J Mardon; G Sebastio; Francisco E Baralle
A role for exon sequences in alternative splicing of the human fibronectin gene.
Nucleic acids research 1987;15(19):7725-33.
1987: Luciano Zardi; Barbara Carnemolla; Annalisa Siri; T E Petersen; G Paolella; G Sebastio; Francisco E Baralle
Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon.
The EMBO journal 1987;6(8):2337-42.
1985: C C Shoulders; N B Myant; A Sidoli; J C Rodriguez; C Cortese; Francisco E Baralle; R Cortese
Molecular cloning of human LDL apolipoprotein B cDNA. Evidence for more than one gene per haploid genome.
Atherosclerosis 1985;58(1-3):277-89.
1985: C S Shelley; C R Sharpe; Francisco E Baralle; C C Shoulders
Comparison of the human apolipoprotein genes. Apo AII presents a unique functional intron-exon junction.
Journal of molecular biology 1985;186(1):43-51.
1985: A Rees; J Stocks; C R Sharpe; M A Vella; C C Shoulders; J Katz; N I Jowett; Francisco E Baralle; D J Galton
Deoxyribonucleic acid polymorphism in the apolipoprotein A-1-C-III gene cluster. Association with hypertriglyceridemia.
The Journal of clinical investigation 1985;76(3):1090-5.
1984: C R Sharpe; A Sidoli; C S Shelley; M A Lucero; C C Shoulders; Francisco E Baralle
Human apolipoproteins AI, AII, CII and CIII. cDNA sequences and mRNA abundance.
Nucleic acids research 1984;12(9):3917-32.
1983: G Paolella; M A Lucero; M H Murphy; Francisco E Baralle
The Alu family repeat promoter has a tRNA-like bipartite structure.
The EMBO journal 1983;2(5):691-6.