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Jong Rok Lee

Research Profile

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Chemicals & Drugs

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Fatty Liver

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Inhibitory Concentration 50

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E Y Jang; H-C Kim; K J Kim; Jong Rok Lee; Meeyul Hwang; S S Yoon; Chae Ha Yang
Liquiritigenin decreases selective molecular and behavioral effects of cocaine in rodents.
Young Mi Kim; Tae Hyun Kim; Young Woo Kim; Yoon Mee Yang; Da Hye Ryu; Se Jin Hwang; Jong Rok Lee; Sang Chan Kim; Sang Geon Kim
Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition.
Young Woo Kim; Young Mi Kim; Yoon Mee Yang; Tae Hyun Kim; Se Jin Hwang; Jong Rok Lee; Sang Chan Kim; Sang Geon Kim
Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis.

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All Publications

2011: E Y Jang; H-C Kim; K J Kim; Jong Rok Lee; Meeyul Hwang; S S Yoon; Chae Ha Yang
Liquiritigenin decreases selective molecular and behavioral effects of cocaine in rodents.
Current neuropharmacology 2011;9(1):30-4.
2010: Young Mi Kim; Tae Hyun Kim; Young Woo Kim; Yoon Mee Yang; Da Hye Ryu; Se Jin Hwang; Jong Rok Lee; Sang Chan Kim; Sang Geon Kim
Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition.
Free radical biology & medicine 2010;49(11):1722-34.
2010: Young Woo Kim; Young Mi Kim; Yoon Mee Yang; Tae Hyun Kim; Se Jin Hwang; Jong Rok Lee; Sang Chan Kim; Sang Geon Kim
Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis.
Free radical biology & medicine 2010;48(4):567-78.
2009: Jong Rok Lee; Sook Jahr Park; Hyeung-Sik Lee; Seon Young Jee; Jungcheol Seo; Young Kyu Kwon; Taeg Kyu Kwon; Sang Chan Kim
Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats.
Evidence-based complementary and alternative medicine : eCAM 2009;6(2):195-201.
2009: Ki Hun Park; Min Suk Yang; Moon Ki Park; Sang Chan Kim; Chae Ha Yang; Sook Jahr Park; Jong Rok Lee
A new cytotoxic guaianolide from Chrysanthemum boreale.
Fitoterapia 2009;80(1):54-6.
2008: Eun Young Jang; Eun Sang Choe; Meeyul Hwang; Sang Chan Kim; Jong Rok Lee; Sang Geon Kim; Jae-Pil Jeon; Russell J Buono; Chae Ha Yang
Isoliquiritigenin suppresses cocaine-induced extracellular dopamine release in rat brain through GABA(B) receptor.
European journal of pharmacology 2008;587(1-3):124-8.
2008: Sang Chan Kim; Sook Jahr Park; Jong Rok Lee; Jung Cheol Seo; Chae Ha Yang; Sung Hui Byun
Cytoprotective Activity of Glycyrrhizae radix Extract Against Arsenite-induced Cytotoxicity.
Evidence-based complementary and alternative medicine : eCAM 2008;5(2):165-71.
2008: Y W Kim; R J Zhao; S J Park; Jong Rok Lee; Il Je Cho; Chae Ha Yang; Sang Geon Kim; Sang Chan Kim
Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-kappaB-dependent iNOS and proinflammatory cytokines production.
British journal of pharmacology 2008;154(1):165-73.
2007: Sang Yeob Han; Jong Rok Lee; Young Kyu Kwon; Mi Jeong Jo; Sook Jahr Park; Sang Chan Kim; Hyeung-Sik Lee; Sae-Kwang Ku
Ostreae Testa prevent ovariectomy-induced bone loss in mice by osteoblast activations.
Journal of ethnopharmacology 2007;114(3):400-5.
2007: Seung-Chul Chun; Seon Young Jee; Sang Gon Lee; Sook Jahr Park; Jong Rok Lee; Sang Chan Kim
Anti-inflammatory activity of the methanol extract of moutan cortex in LPS-activated Raw264.7 cells.
Evidence-based complementary and alternative medicine : eCAM 2007;4(3):327-33.
2006: Young Woo Kim; Sung Hwan Ki; Jong Rok Lee; Song Jin Lee; Choon Won Kim; Sang Chan Kim; Sang Geon Kim
Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine.
Chemico-biological interactions 2006;161(2):125-38.
2005: Gwang-Seong Choi; Moon-Hee Lee; Soon-Ki Kim; Chul-Soo Kim; Hong-Sik Lee; Moon-Whan Im; Hye-Yun Kil; Do Hwan Seong; Jong Rok Lee; Woo-Chul Kim; Min-Geol Lee; Sun U Song
Combined treatment of an intratumoral injection of dendritic cells and systemic chemotherapy (Paclitaxel) for murine fibrosarcoma.
Yonsei medical journal 2005;46(6):835-42.
2005: Rong Jie Zhao; Byung Soo Koo; Geun Woo Kim; Eun Young Jang; Jong Rok Lee; Mi Ryeo Kim; Sang Chan Kim; Young Kyu Kwon; Kwang Joong Kim; Tae-Lin Huh; Dae-Hyun Kim; Insop Shim; Chae Ha Yang
The essential oil from Angelica gigas NAKAI suppresses nicotine sensitization.
Biological & pharmaceutical bulletin 2005;28(12):2323-6.
2003: Tae Joung Ha; Dae Sik Jang; Jong Rok Lee; Kyung Dong Lee; Jun Lee; Seon Woo Hwang; Hwa Jin Jung; Sang Hae Nam; Ki Hun Park; Min Suk Yang
Cytotoxic effects of sesquiterpene lactones from the flowers of Hemisteptia lyrata B.
Archives of pharmacal research 2003;26(11):925-8.
2003: Jong Rok Lee; Min Suk Yang; Jun Lee; Seon Woo Hwang; Yung Hee Kho; Ki Hun Park
New guaianolides from leaves and stems of Chrysanthemum boreale.
Planta medica 2003;69(9):880-2.
2001: Jong Rok Lee; Min Suk Yang; Dae Sik Jang; Tae Joung Ha; K M Park; C H Lee; Y H Kho; Ki Hun Park
A new guaianolide as apoptosis inhibitor from Chrysanthemum boreale.
Planta medica 2001;67(6):585-7.