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Kyung-Tae Lee

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Seung-Hyun Jung; Su Jung Kim; Kyung-Tae Lee; Myung Sook Oh; Seon-Pyo Hong; Dae Sik Jang; Bo-Gyu Jun; Jung-Hye Choi
α-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFκB signalling in RAW 264.7 cells.
Tae Hoon Kwon; Kyung-Tae Lee; Young Hun Lee; Ji-Sun Shin; Ik Hwan Yoon; Bong Jin Kwon; Yong Sup Lee
Synthesis of indolyl-3-acetonitrile derivatives and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells.
Jong-Gyu Lee; Kyung-Tae Lee; Ji-Hye Ahn; Nam-In Baek; Ji-Hyun Kim; Jung-Hye Choi
Jaceosidin, isolated from dietary mugwort (Artemisia princeps), induces G2/M cell cycle arrest by inactivating cdc25C-cdc2 via ATM-Chk1/2 activation.

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2013: Seung-Hyun Jung; Su Jung Kim; Kyung-Tae Lee; Myung Sook Oh; Seon-Pyo Hong; Dae Sik Jang; Bo-Gyu Jun; Jung-Hye Choi
α-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFκB signalling in RAW 264.7 cells.
Journal of ethnopharmacology 2013;147(1):208-14.
2013: Tae Hoon Kwon; Kyung-Tae Lee; Young Hun Lee; Ji-Sun Shin; Ik Hwan Yoon; Bong Jin Kwon; Yong Sup Lee
Synthesis of indolyl-3-acetonitrile derivatives and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells.
Bioorganic & medicinal chemistry letters 2013;23(9):2571-4.
2013: Jong-Gyu Lee; Kyung-Tae Lee; Ji-Hye Ahn; Nam-In Baek; Ji-Hyun Kim; Jung-Hye Choi
Jaceosidin, isolated from dietary mugwort (Artemisia princeps), induces G2/M cell cycle arrest by inactivating cdc25C-cdc2 via ATM-Chk1/2 activation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;55():214-21.
2013: Hye-Eun Choi; Jung-Hye Choi; Gyu Il Kim; Je Hak Kim; Ji Han Kim; Joo Han Lee; Joon Kwang Lee; Jae Yeol Lee; Soo Heui Paik; Yong Park; Yong Ha Chi; Kyung-Tae Lee
Synthesis and evaluation of nicotinamide derivative as anti-angiogenic agents.
Bioorganic & medicinal chemistry letters 2013;23(7):2083-8.
2013: Ji-Hyung Seo; Wang-Sup Shim; Young-Wuk Cho; Min-Ho Jo; Gyu-Jeong Noh; Ji-Sun Park; Mi-Sun Park; Ju-Hee Ryu; Kyung-Tae Lee
Rapid and sensitive LC-MS/MS method for determination of megestrol acetate in human plasma: application to a human pharmacokinetic study.
Biomedical chromatography : BMC 2013;27(4):409-15.
2013: Ji-Sun Shin; Kyung-Jin Yun; Hee-Juhn Park; Kyeong-Hwa Seo; Nam-In Baek; Young-Wuk Cho; Kyung-Sook Chung; Daesik Jang; Kyung-Tae Lee
Monotropein isolated from the roots of Morinda officinalis ameliorates proinflammatory mediators in RAW 264.7 macrophages and dextran sulfate sodium (DSS)-induced colitis via NF-κB inactivation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;53():263-71.
2013: Ji-Hyun Kim; Kyung-Tae Lee; Yeong-In Yang; Seung-Hyun Jung; Ji-Hye Ahn; Nam-In Baek; Jin-Gyeong Cho; Jung-Hye Choi
Artemisia leaf extract induces apoptosis in human endometriotic cells through regulation of the p38 and NFκB pathways.
Journal of ethnopharmacology 2013;145(3):767-75.
2013: Jae-Won Jang; Min-Ho Jo; Young-Joo Lee; Ji-Hyung Seo; Sung-Vin Yim; Young-Wuk Cho; Kyung-Tae Lee
Relative bioavailability of levodropropizine 60 mg capsule and syrup formulations in healthy male Korean volunteers: a singledose, randomized-sequence, open-label, two-way crossover study.
International journal of clinical pharmacology and therapeutics 2013;51(2):152-60.
2013: Suran Ryu; Ji-Sun Shin; Soo Heui Paik; Yong Ha Chi; Young-Wuk Cho; Hyoung Kook Kim; Ji Han Kim; Je Hak Kim; Joo Han Lee; Kyung-Tae Lee
Fimasartan, anti-hypertension drug, suppressed inducible nitric oxide synthase expressions via nuclear factor-kappa B and activator protein-1 inactivation.
Biological & pharmaceutical bulletin 2013;36(3):467-74.
2013: Kijae Lee; Kyung-Tae Lee; Van Chung Pham; Yeon Gyu Yu; Min Ji Choi; Seong-Gu Han; Kyung Ju Kim; Jae Yeol Lee
Fragment-based discovery of novel and selective mPGES-1 inhibitors Part 1: identification of sulfonamido-1,2,3-triazole-4,5-dicarboxylic acid.
Bioorganic & medicinal chemistry letters 2013;23(1):75-80.
2012: Hong-Kun Rim; Jin Yeong Park; Young-Wuk Cho; Heung Woo Choi; Il Sook Choi; Jung-Hye Choi; Heon-Woo Lee; Jae Yeol Lee; Kyung-Tae Lee
T-type Ca2+ channel blocker, KYS05047 induces G1 phase cell cycle arrest by decreasing intracellular Ca2+ levels in human lung adenocarcinoma A549 cells.
Bioorganic & medicinal chemistry letters 2012;22(23):7123-6.
2012: Yeong-In Yang; Youn Seok Choi; Tae Jin Kim; Kyung-Tae Lee; Hee-Juhn Park; Ie-Ming Shih; Jung-Hye Choi
Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFκB pathway.
Carcinogenesis 2012;33(12):2488-98.
2012: Min-Sang Yoo; Ji-Sun Shin; Nam-In Baek; Myun-Ho Bang; Young-Wuk Cho; Hye-Eun Choi; Kyung-Tae Lee
Fucosterol isolated from Undaria pinnatifida inhibits lipopolysaccharide-induced production of nitric oxide and pro-inflammatory cytokines via the inactivation of nuclear factor-κB and p38 mitogen-activated protein kinase in RAW264.7 macrophages.
Food chemistry 2012;135(3):967-75.
2012: Hong-Kun Rim; Sang Hyun Sung; Woong Cho; Kyung-Tae Lee
Nodakenin suppresses lipopolysaccharide-induced inflammatory responses in macrophage cells by inhibiting tumor necrosis factor receptor-associated factor 6 and nuclear factor-κB pathways and protects mice from lethal endotoxin shock.
The Journal of pharmacology and experimental therapeutics 2012;342(3):654-64.
2012: Kyung-Won Lee; Hee-Jun Park; Ji-Hyung Seo; Sung-Vin Yim; Jung-Hye Choi; Kyung-Sook Chung; Kyung-Tae Lee
Sulfuretin from heartwood of Rhus verniciflua triggers apoptosis through activation of Fas, Caspase-8, and the mitochondrial death pathway in HL-60 human leukemia cells.
Journal of cellular biochemistry 2012;113(9):2835-44.
2012: Mi-Sun Park; Wang-Seob Shim; Sung-Vin Yim; Kyung-Tae Lee
Development of simple and rapid LC-MS/MS method for determination of celecoxib in human plasma and its application to bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;902():137-41.
2012: Hyo-Jin An; Gil-Goo Lee; Kyung-Tae Lee
Drynariae rhizoma increases immune response in mice.
Natural product communications 2012;7(7):905-8.
2012: In-Tae Kim; Hee-Juhn Park; Suran Ryu; Ji-Sun Shin; Jung-Hye Choi; Kyung-Tae Lee
Euscaphic acid isolated from roots of Rosa rugosa inhibits LPS-induced inflammatory responses via TLR4-mediated NF-κB inactivation in RAW 264.7 macrophages.
Journal of cellular biochemistry 2012;113(6):1936-46.
2012: Hye-Kyung Ju; Heon-Woo Lee; Nam-In Baek; Jin-Gyeong Cho; Jung-Hye Choi; Hae-Gon Chung; Kyung-Sook Chung; Kyung-Tae Lee
Standardized flavonoid-rich fraction of Artemisia princeps Pampanini cv. Sajabal induces apoptosis via mitochondrial pathway in human cervical cancer HeLa cells.
Journal of ethnopharmacology 2012;141(1):460-8.
2012: Ji-Hyun Kim; Jong-Gyu Lee; Kyung-Tae Lee; Yeong-In Yang; Ji-Hye Ahn; Jung-Hye Choi
Deer (Cervus elaphus) antler extract suppresses adhesion and migration of endometriotic cells and regulates MMP-2 and MMP-9 expression.
Journal of ethnopharmacology 2012;140(2):391-7.
2012: Ji-Sun Shin; Min-Sang Yoo; Young-Wuk Cho; Jae-Yeol Lee; Young-Su Noh; Kyung-Tae Lee
Anti-inflammatory and anti-arthritic effects of new synthetic 3-(4-hydroxyphenyl)-4-(4-thiomethoxyphenyl)-1H-pyrrole-2,5-dione.
Bioorganic & medicinal chemistry letters 2012;22(6):2221-5.
2012: Yeong-In Yang; Seong Ho Kim; Kyung-Tae Lee; Woong-Yang Park; Hyeon-Cheol Shin; Jung-Hye Choi
6,6'-Bieckol, isolated from marine alga Ecklonia cava, suppressed LPS-induced nitric oxide and PGE₂ production and inflammatory cytokine expression in macrophages: the inhibition of NFκB.
International immunopharmacology 2012;12(3):510-7.
2012: Ji-Sun Shin; Seung-Jae Park; Suran Ryu; Young-Wuk Cho; Jung-Hye Choi; Han Byul Kang; Tae Woo Kim; Jae-Yeol Lee; Kyung-Tae Lee
Potent anti-inflammatory effect of a novel furan-2,5-dione derivative, BPD, mediated by dual suppression of COX-2 activity and LPS-induced inflammatory gene expression via NF-κB inactivation.
British journal of pharmacology 2012;165(6):1926-40.
2012: Tae Woo Kim; Joon Kwang Lee; Yong Ha Chi; Ji Han Kim; Kyung-Tae Lee; Byoung Wook Yoo; Jae Yeol Lee
Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.
Bioorganic & medicinal chemistry letters 2012;22(4):1649-54.
2011: Yeong-In Yang; Ji-Hyun Kim; Kyung-Tae Lee; Jung-Hye Choi
Costunolide induces apoptosis in platinum-resistant human ovarian cancer cells by generating reactive oxygen species.
Gynecologic oncology 2011;123(3):588-96.
2011: Ji-Sun Shin; Chang Hyeon Yun; Nam-In Baek; Young-Wuk Cho; Myung-Sook Choi; Hae-Gon Chung; Tae-Sook Jeong; Kyung-Tae Lee
Indole-containing fractions of Brassica rapa inhibit inducible nitric oxide synthase and pro-inflammatory cytokine expression by inactivating nuclear factor-κB.
Journal of medicinal food 2011;14(12):1527-37.
2011: Eu-Jin Cho; Young-Wuk Cho; Hye-Eun Choi; Jung-Hye Choi; Hyung-Min Kim; Jane Ko; Hyo-Jin An; Ji-Sun Shin; Kyung-Tae Lee
Roxatidine suppresses inflammatory responses via inhibition of NF-κB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages.
Journal of cellular biochemistry 2011;112(12):3648-59.
2011: Ji-Sun Shin; Se-Il Sohn; Seung Ryel Baek; Young-Wuk Cho; Kyung-Tae Lee
Anti-inflammatory effect of pelubiprofen, 2-[4-(oxocyclohexylidenemethyl)-phenyl]propionic acid, mediated by dual suppression of COX activity and LPS-induced inflammatory gene expression via NF-κB inactivation.
Journal of cellular biochemistry 2011;112(12):3594-603.
2011: Hye-Eun Choi; Jung-Hye Choi; Gyu Il Kim; Je Hak Kim; Ji Han Kim; Joo Han Lee; Joon Kwang Lee; Jae Yeol Lee; Soo Heui Paik; Yong Park; Min-Sang Yoo; Yong Ha Chi; Kyung-Tae Lee
BRN-103, a novel nicotinamide derivative, inhibits VEGF-induced angiogenesis and proliferation in human umbilical vein endothelial cells.
Bioorganic & medicinal chemistry letters 2011;21(21):6236-41.
2011: Ji-Sun Shin; Yong Sup Lee; Young-Su Noh; Nam-In Baek; Young-Wuk Cho; Myung-Sook Choi; Hae-Gon Chung; Tae-Sook Jeong; Eunkyung Kang; Kyung-Tae Lee
Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinase.
British journal of pharmacology 2011;164(1):145-58.
2011: Seo Young Shin; Kyung-Tae Lee; Ji-Sun Shin; Min Cheol Shin; Yong Sup Lee
Synthesis of aurones and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells.
Bioorganic & medicinal chemistry letters 2011;21(15):4520-3.
2011: Jung-Hoon Cho; Ji-Hye Ahn; Nam-In Baek; Ji-Hyun Kim; Jong-Gyu Lee; Kyung-Tae Lee; Yeong-In Yang; Jung-Hye Choi
Eupatilin, a dietary flavonoid, induces G2/M cell cycle arrest in human endometrial cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(8):1737-44.
2011: Hyo-Jin An; In-Tae Kim; Hee-Juhn Park; Hyung-Min Kim; Jung-Hye Choi; Kyung-Tae Lee
Tormentic acid, a triterpenoid saponin, isolated from Rosa rugosa, inhibited LPS-induced iNOS, COX-2, and TNF-α expression through inactivation of the nuclear factor-κb pathway in RAW 264.7 macrophages.
International immunopharmacology 2011;11(4):504-10.
2011: Jung-Hye Choi; Kyung-Tae Lee; Peter C K Leung
Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth.
Carcinogenesis 2011;32(4):589-96.
2011: Se-Il Sohn; Hee-Juhn Park; Jae-Hoon Park; Hong-Kun Rim; Jung-Hye Choi; Jong-Won Choi; Seo-Young Jeong; Soo-Dong Kim; Yang-Hee Kim; Kyung-Tae Lee
The ameliorative effect of 23-hydroxytormentic acid isolated from Rubus coreanus on cisplatin-induced nephrotoxicity in rats.
Biological & pharmaceutical bulletin 2011;34(9):1508-13.
2011: Yang-Hee Kim; Jung-Hye Choi; Hong-Kun Rim; Hyun-Jun Kang; Sung-Goo Chang; Jae-Hoon Park; Hee-Juhn Park; Jong-Won Choi; Soo-Dong Kim; Kyung-Tae Lee
23-Hydroxytormentic acid and niga-ichgoside f₁ isolated from Rubus coreanus attenuate cisplatin-induced cytotoxicity by reducing oxidative stress in renal epithelial LLC-PK₁ cells.
Biological & pharmaceutical bulletin 2011;34(6):906-11.
2010: Kyung-Jae Won; Kyung-Sook Chung; Yong Sup Lee; Muhammad Shaiq Alia; Muhammad Kashif Pervez; Samreen Fatima; Jung-Hye Choi; Kyung-Tae Lee
Haplophytin-A induces caspase-8-mediated apoptosis via the formation of death-inducing signaling complex in human promyelocytic leukemia HL-60 cells.
Chemico-biological interactions 2010;188(3):505-11.
2010: So-Jung Won; Kyung-Sook Chung; Yo Sook Ki; Jung-Hye Choi; Won-Jea Cho; Kyung-Tae Lee
CWJ-081, a novel 3-arylisoquinoline derivative, induces apoptosis in human leukemia HL-60 cells partially involves reactive oxygen species through c-Jun NH2-terminal kinase pathway.
Bioorganic & medicinal chemistry letters 2010;20(22):6447-51.
2010: Soo Yeon Jung; So Hyung Lee; Han Byul Kang; Hang Ah Park; Sun Ki Chang; Jungahn Kim; Dong Joon Choo; Chun Rim Oh; Young Deuk Kim; Ji Hyung Seo; Kyung-Tae Lee; Jae Yeol Lee
Antitumor activity of 3,4-dihydroquinazoline dihydrochloride in A549 xenograft nude mice.
Bioorganic & medicinal chemistry letters 2010;20(22):6633-6.
2010: Myung-Jae Lee; Heon-Woo Lee; Jong-Min Kang; Ji-Hyung Seo; Seong-Kun Tak; Wangseob Shim; Sung-Vin Yim; Seung Jae Hong; Kyung-Tae Lee
Application of a rapid and selective method for the simultaneous determination of carebastine and pseudoephedrine in human plasma by liquid chromatography-electrospray mass spectrometry for bioequivalence study in Korean subjects.
Biomedical chromatography : BMC 2010;24(10):1031-7.
2010: Kyung-Sook Chung; Jung-Hye Choi; Nam-In Back; Myung-Sook Choi; Eun-Kyung Kang; Hae-Gon Chung; Tae-Sook Jeong; Kyung-Tae Lee
Eupafolin, a flavonoid isolated from Artemisia princeps, induced apoptosis in human cervical adenocarcinoma HeLa cells.
Molecular nutrition & food research 2010;54(9):1318-28.
2010: Ji-Sun Shin; Young Mi Park; Jung-Hye Choi; Hee-Juhn Park; Min Cheol Shin; Yong Sup Lee; Kyung-Tae Lee
Sulfuretin isolated from heartwood of Rhus verniciflua inhibits LPS-induced inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines expression via the down-regulation of NF-kappaB in RAW 264.7 murine macrophage cells.
International immunopharmacology 2010;10(8):943-50.
2010: Dong Hyun Kim; Byung Hoon Yoon; Won Yong Jung; Jong Min Kim; Se Jin Park; Dong Hyun Park; Youngbuhm Huh; Chan Park; Jae Hoon Cheong; Kyung-Tae Lee; Chan Young Shin; Jong Hoon Ryu
Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice.
Neuropharmacology 2010;59(1-2):20-30.
2010: Se Jin Park; Dong Hyun Kim; Il Kyun Lee; Won Yong Jung; Dong Hyun Park; Jong Min Kim; Kang Ro Lee; Kyung-Tae Lee; Chan Young Shin; Jae Hoon Cheong; Kwang Ho Ko; Jong Hoon Ryu
The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(6):1671-6.
2010: Jong-Heon Won; Ji-Sun Shin; Hee-Juhn Park; Hyun-Ju Jung; Duck-Jae Koh; Baek-Geon Jo; Jin-Yong Lee; Kijoo Yun; Kyung-Tae Lee
Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells.
Planta medica 2010;76(3):251-7.
2010: Jong Taik Moon; Ji Young Jeon; Hang Ah Park; Young-Soo Noh; Kyung-Tae Lee; Jungahn Kim; Dong Joon Choo; Jae Yeol Lee
Synthesis and PGE(2) production inhibition of 1H-furan-2,5-dione and 1H-pyrrole-2,5-dione derivatives.
Bioorganic & medicinal chemistry letters 2010;20(2):734-7.
2010: So-Jung Won; Yo Sook Ki; Kyung-Sook Chung; Jung-Hye Choi; Ki Hwan Bae; Kyung-Tae Lee
3α,23-isopropylidenedioxyolean-12-en-27-oic acid, a triterpene isolated from Aceriphyllum rossii, induces apoptosis in human cervical cancer HeLa cells through mitochondrial dysfunction and endoplasmic reticulum stress.
Biological & pharmaceutical bulletin 2010;33(9):1620-6.
2009: Sang-Jun Choi; Ju-Hee Ryu; Heon-Woo Lee; Myung-Jae Lee; Ji-Hyung Seo; Seong-Kun Tak; Kyung-Tae Lee
Rapid and simple method for determination of cephradine in human plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS): application to the bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(31):4059-64.
2009: Jung-Hye Choi; Kyung-Tae Lee
Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation.
Biological & pharmaceutical bulletin 2009;32(10):1803-8.
2009: Kyung-Jin Yun; Ji-Sun Shin; Jung-Hye Choi; Nam-In Back; Hae-Gon Chung; Kyung-Tae Lee
Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE(2), and pro-inflammatory cytokines production via the down-regulation of NF-kappaB in RAW 264.7 murine macrophage cells.
International immunopharmacology 2009;9(11):1323-31.
2009: Woong Cho; Joo-Won Nam; Hyun-Jun Kang; Tri Windono; Eun-Kyoung Seo; Kyung-Tae Lee
Zedoarondiol isolated from the rhizoma of Curcuma heyneana is involved in the inhibition of iNOS, COX-2 and pro-inflammatory cytokines via the downregulation of NF-kappaB pathway in LPS-stimulated murine macrophages.
International immunopharmacology 2009;9(9):1049-57.
2009: Ji-Yeon Kim; Ji-Sun Shin; Jong Hoon Ryu; Sun Yeou Kim; Young-Wuk Cho; Jung-Hye Choi; Kyung-Tae Lee
Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(7):1610-7.
2009: Jong-Hwan Kim; Young-Mi Park; Ji-Sun Shin; Seung Jae Park; Jung-Hye Choi; Hyun-Ju Jung; Hee-Juhn Park; Kyung-Tae Lee
Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells.
Biological & pharmaceutical bulletin 2009;32(6):1062-8.
2009: Kyung-Min Shin; Liulan Shen; Seung Jae Park; Jin-Hyun Jeong; Kyung-Tae Lee
Bis-(3-hydroxyphenyl) diselenide inhibits LPS-stimulated iNOS and COX-2 expression in RAW 264.7 macrophage cells through the NF-kappaB inactivation.
The Journal of pharmacy and pharmacology 2009;61(4):479-86.
2009: Sung-Su Kim; Heon-Woo Lee; Kyung-Tae Lee
Validated method for determination of mazindol in human plasma by liquid chromatography/tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(10):1011-6.
2009: Jong-Min Han; Min-Jung Kim; Seung-Hwa Baek; Sojin An; Yue-Yan Jin; Hae-Gon Chung; Nam-In Baek; Myung-Sook Choi; Kyung-Tae Lee; Tae-Sook Jeong
Antiatherosclerotic effects of Artemisia princeps Pampanini cv. Sajabal in LDL receptor deficient mice.
Journal of agricultural and food chemistry 2009;57(4):1267-74.
2009: Sung-Hee Cho; Kyung-Sook Chung; Jung-Hye Choi; Dong-Hyun Kim; Kyung-Tae Lee
Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells.
BMC cancer 2009;9():449.
2008: Ju-Hee Ryu; Sang-Jun Choi; Heon-Woo Lee; Seung-Ki Choi; Kyung-Tae Lee
Quantification of roxatidine in human plasma by liquid chromatography electrospray ionization tandem mass spectrometry: application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;876(1):143-7.
2008: Kyung-Jin Yun; Duck-Jae Koh; Shi-Hye Kim; Seung Jae Park; Jong Hoon Ryu; Deog-Gon Kim; Jin-Yong Lee; Kyung-Tae Lee
Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-kappaB inactivation.
Journal of agricultural and food chemistry 2008;56(21):10265-72.
2008: Jung-Hye Choi; Heon-Woo Lee; Hee-Juhn Park; Sung-Hoon Kim; Kyung-Tae Lee
Kalopanaxsaponin A induces apoptosis in human leukemia U937 cells through extracellular Ca2+ influx and caspase-8 dependent pathways.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(11):3486-92.
2008: Myun-Ho Bang; Min-Woo Han; Myoung-Chong Song; Jin-Gyeong Cho; Hae-Gon Chung; Tae-Sook Jeong; Kyung-Tae Lee; Myung-Sook Choi; Se-Young Kim; Nam-In Baek
A cytotoxic and apoptosis-inducing sesquiterpenoid isolated from the aerial parts of Artemisia princeps PAMPANINI (Sajabalssuk).
Chemical & pharmaceutical bulletin 2008;56(8):1168-72.
2008: Eun Young Park; Kyung-Won Lee; Heon-Woo Lee; Young-Wuk Cho; Nam-In Baek; Hae-Gon Chung; Tae-Sook Jeong; Myung-Sook Choi; Kyung-Tae Lee
The ethanol extract from Artemisia princeps Pampanini induces p53-mediated G1 phase arrest in A172 human neuroblastoma cells.
Journal of medicinal food 2008;11(2):237-45.
2008: Ji-Yeon Kim; Seung Jae Park; Kyung-Jin Yun; Young-Wuk Cho; Hee-Juhn Park; Kyung-Tae Lee
Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages.
European journal of pharmacology 2008;584(1):175-84.
2008: Min-Jung Kim; Jong-Min Han; Yue-Yan Jin; Nam-In Baek; Myun-Ho Bang; Hae-Gon Chung; Myung-Sook Choi; Kyung-Tae Lee; Dai-Eun Sok; Tae-Sook Jeong
In vitro antioxidant and anti-inflammatory activities of Jaceosidin from Artemisia princeps Pampanini cv. Sajabal.
Archives of pharmacal research 2008;31(4):429-37.
2008: Kyung-Jin Yun; Ji-Yeon Kim; Jong Bin Kim; Kyung-Won Lee; Seo Young Jeong; Hee-Juhn Park; Hyun-Ju Jung; Young-Wuk Cho; Kijoo Yun; Kyung-Tae Lee
Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-kappa B inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways.
International immunopharmacology 2008;8(3):431-41.
2008: Hyun-Soo Lee; Il-Mo Kang; Heon-Woo Lee; Ji-Hyung Seo; Ju-Hee Ryu; Sang-Jun Choi; Myung-Jae Lee; Seo Young Jeong; Young-Wuk Cho; Kyung-Tae Lee
Development and validation of a high performance liquid chromatography-tandem mass spectrometry for the determination of etodolac in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;863(1):158-62.
2008: Heon-Woo Lee; Ji-Hyung Seo; Hyun-Su Lee; Seo Young Jeong; Young-Wuk Cho; Kyung-Tae Lee
Development of a liquid chromatography/negative-ion electrospray tandem mass spectrometry assay for the determination of cilnidipine in human plasma and its application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;862(1-2):246-51.
2007: Jong Bin Kim; Ah-Reum Han; Eun-Young Park; Ji-Yeon Kim; Woong Cho; Jun Lee; Eun-Kyoung Seo; Kyung-Tae Lee
Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells.
Biological & pharmaceutical bulletin 2007;30(12):2345-51.
2007: U J Jung; Nam-In Baek; Hae-Gon Chung; M-H Bang; J-S Yoo; T S Jeong; Kyung-Tae Lee; Y J Kang; M K Lee; H J Kim; J Y Yeo; M S Choi
The anti-diabetic effects of ethanol extract from two variants of Artemisia princeps Pampanini in C57BL/KsJ-db/db mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(10):2022-9.
2007: Dong Hyun Kim; Byung Hoon Yoon; Yong-Won Kim; Seungjoo Lee; Bum Young Shin; Ji Wook Jung; Hyoung Ja Kim; Yong Sup Lee; Jae Sue Choi; Sun Yeou Kim; Kyung-Tae Lee; Jong Hoon Ryu
The seed extract of Cassia obtusifolia ameliorates learning and memory impairments induced by scopolamine or transient cerebral hypoperfusion in mice.
Journal of pharmacological sciences 2007;105(1):82-93.
2007: Kyung-Won Lee; Hyoung Ja Kim; Yong Sup Lee; Hee-Jun Park; Jong-Won Choi; Joohun Ha; Kyung-Tae Lee
Acteoside inhibits human promyelocytic HL-60 leukemia cell proliferation via inducing cell cycle arrest at G0/G1 phase and differentiation into monocyte.
Carcinogenesis 2007;28(9):1928-36.
2007: Seung-Ki Choi; Bo-Rim Seo; Kyung-Won Lee; Woong Cho; Seoung-Hee Jeong; Kyung-Tae Lee
Saucernetin-7 isolated from Saururus chinensis induces caspase-dependent apoptosis in human promyelocytic leukemia HL-60 cells.
Biological & pharmaceutical bulletin 2007;30(8):1516-22.
2007: Heon-Woo Lee; Ji-Hyung Seo; Kyung-Tae Lee
Development and validation of a high-performance liquid chromatography-tandem mass spectrometry for the determination of penciclovir in human plasma: application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;852(1-2):382-8.
2007: Sung-Su Kim; Ho-Taek Im; Il-Mo Kang; Hyun-Su Lee; Heon-Woo Lee; Sung-Hee Cho; Jong Bin Kim; Kyung-Tae Lee
An optimized analytical method of fluconazole in human plasma by high-performance liquid chromatography with ultraviolet detection and its application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;852(1-2):174-9.
2007: Hee-Juhn Park; In-Tae Kim; Jong-Heon Won; Seoung-Hee Jeong; Eun-Young Park; Jung-Hwan Nam; Jongwon Choi; Kyung-Tae Lee
Anti-inflammatory activities of ent-16alphaH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation.
European journal of pharmacology 2007;558(1-3):185-93.
2007: Heon-Woo Lee; Ji-Hyung Seo; Seung-Ki Choi; Kyung-Tae Lee
Determination of itopride in human plasma by liquid chromatography coupled to tandem mass spectrometric detection: application to a bioequivalence study.
Analytica chimica acta 2007;583(1):118-23.
2007: Kyung-Jin Yun; Byung-Sun Min; Ji-Yeon Kim; Kyung-Tae Lee
Styraxoside A isolated from the stem bark of Styrax japonica inhibits lipopolysaccharide-induced expression of inducible nitric oxide synthase and cyclooxygenase-2 in RAW 264.7 cells by suppressing nuclear factor-kappa B activation.
Biological & pharmaceutical bulletin 2007;30(1):139-44.
2006: Yang-Hee Kim; Yong-Won Kim; Young-Jun Oh; Nam-In Back; Sun-A Chung; Hae-Gon Chung; Tae-Sook Jeong; Myung-Sook Choi; Kyung-Tae Lee
Protective effect of the ethanol extract of the roots of Brassica rapa on cisplatin-induced nephrotoxicity in LLC-PK1 cells and rats.
Biological & pharmaceutical bulletin 2006;29(12):2436-41.
2006: Jong-Heon Won; Ji-Yeon Kim; Kyung-Jin Yun; Jin-Hee Lee; Nam-In Back; Hae-Gon Chung; Sun A Chung; Tae-Sook Jeong; Myung-Sook Choi; Kyung-Tae Lee
Gigantol isolated from the whole plants of Cymbidium goeringii inhibits the LPS-induced iNOS and COX-2 expression via NF-kappaB inactivation in RAW 264.7 macrophages cells.
Planta medica 2006;72(13):1181-7.
2006: Heon-Woo Lee; Wan-Su Park; Yong-Won Kim; Sung-Hee Cho; Sung-Su Kim; Ji-Hyung Seo; Kyung-Tae Lee
A rapid and sensitive liquid chromatography/positive ion tandem mass spectrometry method for the determination of cimetropium in human plasma by liquid-liquid extraction.
Journal of mass spectrometry : JMS 2006;41(7):855-60.
2006: Young-Mi Park; Jong-Heon Won; Kyung-Jin Yun; Jong-Hoon Ryu; Yong Nam Han; Seung-Ki Choi; Kyung-Tae Lee
Preventive effect of Ginkgo biloba extract (GBB) on the lipopolysaccharide-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2 via suppression of nuclear factor-kappaB in RAW 264.7 cells.
Biological & pharmaceutical bulletin 2006;29(5):985-90.
2006: Jung-Hwan Nam; Hyun-Ju Jung; Jongwon Choi; Kyung-Tae Lee; Hee-Juhn Park
The anti-gastropathic and anti-rheumatic effect of niga-ichigoside F1 and 23-hydroxytormentic acid isolated from the unripe fruits of Rubus coreanus in a rat model.
Biological & pharmaceutical bulletin 2006;29(5):967-70.
2006: Jong-Heon Won; Ho-Taek Im; Yang-Hee Kim; Kyung-Jin Yun; Hee-Juhn Park; Jong-Won Choi; Kyung-Tae Lee
Anti-inflammatory effect of buddlejasaponin IV through the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via the NF-kappaB inactivation.
British journal of pharmacology 2006;148(2):216-25.
2006: Heon-Woo Lee; Ji-Hyung Seo; Yong-Won Kim; Seo Young Jeong; Kyung-Tae Lee
Determination of zaltoprofen in human plasma by liquid chromatography with electrospray tandem mass spectrometry: Application to a pharmacokinetic study.
Rapid communications in mass spectrometry : RCM 2006;20(18):2675-80.
2006: Sung-Hee Cho; Heon-Woo Lee; Ho-Taek Im; Wan-Su Park; Young-Wook Choi; Jae-Hwan Rew; Kyung-Tae Lee
Rapid and highly sensitive liquid chromatography/electrospray ionization tandem mass spectrometry method for the quantitation of buspirone in human plasma: application to a pharmacokinetic study.
Rapid communications in mass spectrometry : RCM 2006;20(8):1293-8.
2005: Sung-Hee Cho; Ho-Taek Im; Wan-Su Park; Yong-Hwa Ha; Young-Wook Choi; Kyung-Tae Lee
Simple method for the assay of clindamycin in human plasma by reversed-phase high-performance liquid chromatography with UV detector.
Biomedical chromatography : BMC 2005;19(10):783-7.
2005: Young-Mi Park; Jong-Heon Won; Yang-Hee Kim; Jong-Won Choi; Hee-Juhn Park; Kyung-Tae Lee
In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus.
Journal of ethnopharmacology 2005;101(1-3):120-8.
2005: Jong-Heon Won; Sang-Yong Park; Sang-Gil Nam; Hee-Juhn Park; Jong-Won Choi; Kyung-Tae Lee
Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide and cyclooxygenase-2 by chiisanoside via suppression of nuclear factor-kappaB activation in RAW 264.7 macrophage cells.
Biological & pharmaceutical bulletin 2005;28(10):1919-24.
2005: Sung-Hee Cho; Hun-Woo Lee; Ho-Taek Im; Wan-Su Park; Minsun Baek; Kyung-Tae Lee
Quantification of propiverine by liquid chromatography/electrospray tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy subjects.
Journal of pharmaceutical and biomedical analysis 2005;39(3-4):670-6.
2005: Hyun-Ju Jung; Sei-Gun Kim; Jung-Hwan Nam; Kwan-Kyu Park; Won-Yun Chung; Won Bae Kim; Kyung-Tae Lee; Jong-Heon Won; Jong-Won Choi; Hee-Juhn Park
Isolation of saponins with the inhibitory effect on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha production from Pleurospermum kamtschaticum.
Biological & pharmaceutical bulletin 2005;28(9):1668-71.
2005: H W Lee; K J Won; Sung-Hee Cho; Y H Ha; Wan-Su Park; H T Yim; M Baek; J H Rew; S H Yoon; Sung-Vin Yim; J H Chung; Kyung-Tae Lee
Quantitation of niflumic acid in human plasma by high-performance liquid chromatography with ultraviolet absorbance detection and its application to a bioequivalence study of talniflumate tablets.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;821(2):215-20.
2005: Chae-Bin Yoo; Ki-Tae Han; Kyu-Seok Cho; Joohun Ha; Hee-Juhn Park; Jung-Hwan Nam; Uk-Hyun Kil; Kyung-Tae Lee
Eugenol isolated from the essential oil of Eugenia caryophyllata induces a reactive oxygen species-mediated apoptosis in HL-60 human promyelocytic leukemia cells.
Cancer letters 2005;225(1):41-52.
2005: In-Tae Kim; Hee-Juhn Park; Jung-Hwan Nam; Young-Mi Park; Jong-Heon Won; Jongwon Choi; Bong-Keun Choe; Kyung-Tae Lee
In-vitro and in-vivo anti-inflammatory and antinociceptive effects of the methanol extract of the roots of Morinda officinalis.
The Journal of pharmacy and pharmacology 2005;57(5):607-15.
2005: Kyung-Won Lee; Hyun-Ju Jung; Hee-Juhn Park; Deog-Gon Kim; Jin-Yong Lee; Kyung-Tae Lee
Beta-D-xylopyranosyl-(1-->3)-beta-D-glucuronopyranosyl echinocystic acid isolated from the roots of Codonopsis lanceolata induces caspase-dependent apoptosis in human acute promyelocytic leukemia HL-60 cells.
Biological & pharmaceutical bulletin 2005;28(5):854-9.
2005: Hyun-Ju Jung; Jung Hwan Nam; Jongwon Choi; Kyung-Tae Lee; Hee-Juhn Park
Antiinflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan- and Freund's complete adjuvant-induced rats.
Journal of ethnopharmacology 2005;97(2):359-67.
2005: Hyun-Ju Jung; Jung-Hwan Nam; Jongwon Choi; Kyung-Tae Lee; Hee-Juhn Park
19Alpha-hydroxyursane-type triterpenoids: antinociceptive anti-inflammatory principles of the roots of Rosa rugosa.
Biological & pharmaceutical bulletin 2005;28(1):101-4.
2005: In-Tae Kim; Young-Mi Park; Jong-Heon Won; Hyun-Ju Jung; Hee-Juhn Park; Jong-Won Choi; Kyung-Tae Lee
Methanol extract of Xanthium strumarium L. possesses anti-inflammatory and anti-nociceptive activities.
Biological & pharmaceutical bulletin 2005;28(1):94-100.
2004: Kyung-Min Shin; In-Tae Kim; Young-Mi Park; Joohun Ha; Jong-Won Choi; Hee-Juhn Park; Yong Sup Lee; Kyung-Tae Lee
Anti-inflammatory effect of caffeic acid methyl ester and its mode of action through the inhibition of prostaglandin E2, nitric oxide and tumor necrosis factor-alpha production.
Biochemical pharmacology 2004;68(12):2327-36.
2004: Bo-Rim Seo; Chae-Bin Yoo; Hee-Juhn Park; Jong-Won Choi; Kyungwon Seo; Seung-Ki Choi; Kyung-Tae Lee
Saucernetin-8 isolated from Saururus chinensis induced the differentiation of human acute promyelocytic leukemia HL-60 cells.
Biological & pharmaceutical bulletin 2004;27(10):1594-8.
2004: Young-Mi Park; In-Tae Kim; Hee-Juhn Park; Jong-Won Choi; Kun-Young Park; Jae-Dong Lee; Byung-Hyouk Nam; Deog-Gon Kim; Jin-Yong Lee; Kyung-Tae Lee
Anti-inflammatory and anti-nociceptive effects of the methanol extract of Fomes fomentarius.
Biological & pharmaceutical bulletin 2004;27(10):1588-93.
2004: Kyung-Min Shin; Rung-Kyu Kim; Tapondjou Leon Azefack; Lontsi David; Sondengam Beibam Luc; M Iqbal Choudhary; Hee-Juhn Park; Jong-Won Choi; Kyung-Tae Lee
In vitro anti-inflammatory activity of 23-hydroxyursolic acid isolated from Cussonia bancoensis in murine macrophage RAW 264.7 cells.
Planta medica 2004;70(9):803-7.
2004: In-Tae Kim; Young-Mi Park; Kyung-Min Shin; Joohun Ha; Jongwon Choi; Hyun-Ju Jung; Hee-Juhn Park; Kyung-Tae Lee
Anti-inflammatory and anti-nociceptive effects of the extract from Kalopanax pictus, Pueraria thunbergiana and Rhus verniciflua.
Journal of ethnopharmacology 2004;94(1):165-73.
2004: Liulan Shen; Kyung-Min Shin; Kyung-Tae Lee; Ji Hoon Jeong
Synthesis of new diselenide compounds as anti-inflammatory agents.
Archives of pharmacal research 2004;27(8):816-9.
2004: Bo-Rim Seo; Kyung-Won Lee; Joohun Ha; Hee-Jun Park; Jong-Won Choi; Kyung-Tae Lee
Saucernetin-7 isolated from Saururus chinensis inhibits proliferation of human promyelocytic HL-60 leukemia cells via G0/G1 phase arrest and induction of differentiation.
Carcinogenesis 2004;25(8):1387-94.
2004: Seoung-Hee Jeong; Sung-Ja Koo; Joo-Hun Ha; Shi-Yong Ryu; Hee-Juhn Park; Kyung-Tae Lee
Induction of apoptosis by yomogin in human promyelocytic leukemic HL-60 cells.
Biological & pharmaceutical bulletin 2004;27(7):1106-11.
2004: Hyun-Ju Jung; Chong Ock Lee; Kyung-Tae Lee; Jongwon Choi; Hee-Juhn Park
Structure-activity relationship of oleanane disaccharides isolated from Akebia quinata versus cytotoxicity against cancer cells and NO inhibition.
Biological & pharmaceutical bulletin 2004;27(5):744-7.
2004: Kyung-Min Shin; Yang-Hee Kim; Wan-Su Park; Insug Kang; Joohun Ha; Jong-Won Choi; Hee-Juhn Park; Kyung-Tae Lee
Inhibition of methanol extract from the fruits of Kochia scoparia on lipopolysaccharide-induced nitric oxide, prostaglandin [correction of prostagladin] E2, and tumor necrosis factor-alpha production from murine macrophage RAW 264.7 cells.
Biological & pharmaceutical bulletin 2004;27(4):538-43.
2003: Hee-Juhn Park; Ryung-Gue Kim; Bo-Rim Seo; Joohun Ha; Byung-Tae Ahn; Song-Hae Bok; Yong Sup Lee; Hyoung Ja Kim; Kyung-Tae Lee
Saucernetin-7 and saucernetin-8 isolated from Saururus chinensis inhibit the LPS-induced production of nitric oxide and prostaglandin E2 in macrophage RAW264.7 cells.
Planta medica 2003;69(10):947-50.
2003: Hyeon Ka; Hee-Juhn Park; Hyun-Ju Jung; Jong-Won Choi; Kyu-Seok Cho; Joohun Ha; Kyung-Tae Lee
Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells.
Cancer letters 2003;196(2):143-52.
2003: Hyun-Ju Jung; Hee-Juhn Park; Ryung-Gue Kim; Kyung-Min Shin; Joohun Ha; Jong-Won Choi; Hyoung Ja Kim; Yong Sup Lee; Kyung-Tae Lee
In vivo anti-inflammatory and antinociceptive effects of liriodendrin isolated from the stem bark of Acanthopanax senticosus.
Planta medica 2003;69(7):610-6.
2003: Ryung-Gue Kim; Kyung-Min Shin; Young-Kwan Kim; Hyeh-Jean Jeong; Joohun Ha; Jong-Won Choi; Hee-Juhn Park; Kyung-Tae Lee
Inhibition of methanol extract from the aerial parts of Saururus chinensis on lipopolysaccharide-induced nitric oxide and prostagladin E2 production from murine macrophage RAW 264.7 cells.
Biological & pharmaceutical bulletin 2003;26(4):481-6.
2002: Kyung-Tae Lee; Sung-Ja Koo; Seung-Hee Jung; Jongwon Choi; Hyun-Ju Jung; Hee-Juhn Park
Structure of three new terpenoids, spiciformisins a and b, and monocyclosqualene, isolated from the herbs of Ligularia fischeri var. spiciformis and cytotoxicity.
Archives of pharmacal research 2002;25(6):820-3.
2002: Jung-Hye Choi; Joohun Ha; Jae-Hoon Park; Jae Yeol Lee; Yong Sup Lee; Hee-Juhn Park; Jong-Won Choi; Yutaka Masuda; Kazuyasu Nakaya; Kyung-Tae Lee
Costunolide triggers apoptosis in human leukemia U937 cells by depleting intracellular thiols.
Japanese journal of cancer research : Gann 2002;93(12):1327-33.
2002: Jung-Hye Choi; Kyung-Min Shin; Na-Young Kim; Jung-Pyo Hong; Yong Sup Lee; Hyoung Ja Kim; Hee-Juhn Park; Kyung-Tae Lee
Taraxinic acid, a hydrolysate of sesquiterpene lactone glycoside from the Taraxacum coreanum NAKAI, induces the differentiation of human acute promyelocytic leukemia HL-60 cells.
Biological & pharmaceutical bulletin 2002;25(11):1446-50.
2002: Seoung-Hee Jeong; Sung Ja Koo; Jung-Hye Choi; Jae-Hoon Park; Joohun Ha; Hee-Juhn Park; Kyung-Tae Lee
Intermedeol isolated from the leaves of Ligularia fischeri var. spiciformis induces the differentiation of human acute promyeocytic leukemia HL-60 Cells.
Planta medica 2002;68(10):881-5.
2002: Jung-Hye Choi; Bo-Rim Seo; Seong-Hoon Seo; Kyung-Tae Lee; Jae-Hoon Park; Hee-Juhn Park; Jong-Won Choi; Yoshie Itoh; Ken-ichi Miyamoto
Costunolide induces differentiation of human leukemia HL-60 cells.
Archives of pharmacal research 2002;25(4):480-4.
2002: Kyung-Tae Lee; Jongwon Choi; Won-Tae Jung; Jung-Hwan Nam; Hyun-Ju Jung; Hee-Juhn Park
Structure of a new echinocystic acid bisdesmoside isolated from Codonopsis lanceolata roots and the cytotoxic activity of prosapogenins.
Journal of agricultural and food chemistry 2002;50(15):4190-3.
2002: Young-Kwan Kim; Ryung-Gue Kim; So-Jung Park; Joo-Hun Ha; Jong-Won Choi; Hee-Juhn Park; Kyung-Tae Lee
In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells.
Biological & pharmaceutical bulletin 2002;25(4):472-6.
2001: Kyung-Tae Lee; IC Sohn; Young-Kwan Kim; Jung-Hye Choi; Jong-Won Choi; Hee-Juhn Park; Y Itoh; KJ Miyamoto
Tectorigenin, an isoflavone of Pueraria thunbergiana Benth., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells.
Biological & pharmaceutical bulletin 2001;24(10):1117-21.
2001: M G Lee; Kyung-Tae Lee; Sung-Gil Chi; Jae-Hoon Park
Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release.
Biological & pharmaceutical bulletin 2001;24(3):303-6.
2001: Kyung-Tae Lee; Jung-Hye Choi; Dong-Hyun Kim; K H Son; W B Kim; S H Kwon; Hee-Juhn Park
Constituents and the antitumor principle of Allium victorialis var. platyphyllum.
Archives of pharmacal research 2001;24(1):44-50.
2000: Hee-Juhn Park; S H Kwon; K O Yoo; IC Sohn; Kyung-Tae Lee; H K Lee
Sesquiterpenes from the leaves of Ligularia fischeri var. spiciformis.
Planta medica 2000;66(8):783-4.
2000: Kyung-Tae Lee; IC Sohn; Dong-Hyun Kim; Jong-Won Choi; S H Kwon; Hee-Juhn Park
Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro.
Archives of pharmacal research 2000;23(5):461-6.
2000: Kyung-Tae Lee; JI Kim; Hee-Juhn Park; K O Yoo; Yong Nam Han; KJ Miyamoto
Differentiation-inducing effect of magnolialide, a 1 beta-hydroxyeudesmanolide isolated from Cichorium intybus, on human leukemia cells.
Biological & pharmaceutical bulletin 2000;23(8):1005-7.
2000: Kyung-Tae Lee; IC Sohn; Hee-Juhn Park; D W Kim; G O Jung; K Y Park
Essential moiety for antimutagenic and cytotoxic activity of hederagenin monodesmosides and bisdesmosides isolated from the stem bark of Kalopanax pictus.
Planta medica 2000;66(4):329-32.
1999: Eun-Ah Bae; Myung Joo Han; Kyung-Tae Lee; Jong-Won Choi; Hee-Juhn Park; Dong-Hyun Kim
Metabolism of 6"-O-xylosyltectoridin and tectoridin by human intestinal bacteria and their hypoglycemic and in vitro cytotoxic activities.
Biological & pharmaceutical bulletin 1999;22(12):1314-8.
1999: Kyung-Tae Lee; JI Kim; Y S Rho; Sung-Goo Chang; Jee-Chang Jung; Jae-Hoon Park; Hee-Juhn Park; KJ Miyamoto
Hypericin induces both differentiation and apoptosis in human promyelocytic leukemia HL-60 cells.
Biological & pharmaceutical bulletin 1999;22(12):1271-4.
1999: Dong-Hyun Kim; Kyung-Tae Lee; Eun-Ah Bae; Myung Joo Han; Hee-Juhn Park
Metabolism of liriodendrin and syringin by human intestinal bacteria and their relation to in vitro cytotoxicity.
Archives of pharmacal research 1999;22(1):30-4.
1999: YS Rho; Kyung-Tae Lee; Jee-Chang Jung; C Yoon; Z An; RM Hoffman; Sung-Goo Chang
Efficacy of new platinum analog DPPE in an orthotopic nude mouse model of human colon cancer.
Anticancer research 1999;19(1A):157-61.
1998: JI Kim; Jae-Hoon Park; Hee-Juhn Park; Seung-Ki Choi; Kyung-Tae Lee
Induction of differentiation of the human histocytic lymphoma cell line U-937 by hypericin.
Archives of pharmacal research 1998;21(1):41-5.
1997: I J Kim; Y J Park; JI Kim; Kyung-Tae Lee; S K Kim
Studies on the synthesis andin vitro anti-tumor activity of dihydroberberine derivatives.
Archives of pharmacal research 1997;20(5):476-9.
1997: Sung-Goo Chang; JI Kim; Jee-Chang Jung; YS Rho; Kyung-Tae Lee; Z An; X Wang; RM Hoffman
Antimetastatic activity of the new platinum analog [Pt(cis-dach) (DPPE).2NO3] in a metastatic model of human bladder cancer.
Anticancer research 1997;17(5A):3239-42.