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Kuk-Wha Lee

Research Profile

Chemicals & Drugs

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Publications

TOP 3
David B Seligson; Sheila Tze; Hong Yu; Pinchas Cohen; Allan J Pantuck; Jonathan Said; Kuk-Wha Lee
IGFBP-3 nuclear localization predicts human prostate cancer recurrence.
P M Yamada; H H Mehta; D Hwang; K P Roos; Andrea L Hevener; Kuk-Wha Lee
Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.
Vladislava Paharkova-Vatchkova; Kuk-Wha Lee
Nuclear export and mitochondrial and endoplasmic reticulum localization of IGF-binding protein 3 regulate its apoptotic properties.

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All Publications

2013: David B Seligson; Sheila Tze; Hong Yu; Pinchas Cohen; Allan J Pantuck; Jonathan Said; Kuk-Wha Lee
IGFBP-3 nuclear localization predicts human prostate cancer recurrence.
Hormones & cancer 2013;4(1):12-23.
2010: P M Yamada; H H Mehta; D Hwang; K P Roos; Andrea L Hevener; Kuk-Wha Lee
Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.
Endocrinology 2010;151(12):5741-50.
2010: Vladislava Paharkova-Vatchkova; Kuk-Wha Lee
Nuclear export and mitochondrial and endoplasmic reticulum localization of IGF-binding protein 3 regulate its apoptotic properties.
Endocrine-related cancer 2010;17(2):293-302.
2010: Phuong T Hoang; Patricia Park; Laura J Cobb; Valdislava Paharkova-Vatchkova; Michael Hakimi; Pinchas Cohen; Kuk-Wha Lee
The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice.
Metabolism: clinical and experimental 2010;59(3):343-9.
2010: Yue Jia; Kuk-Wha Lee; Ronald Swerdloff; David Hwang; Laura J Cobb; Amiya Sinha Hikim; Yanhe Lue; Pinchas Cohen; Christina Wang
Interaction of insulin-like growth factor-binding protein-3 and BAX in mitochondria promotes male germ cell apoptosis.
The Journal of biological chemistry 2010;285(3):1726-32.
2010: Yanhe Lue; Ronald Swerdloff; QingHai Liu; Hemal Mehta; Amiya Sinha Hikim; Kuk-Wha Lee; Yue Jia; David Hwang; Laura J Cobb; Pinchas Cohen; Christina Wang
Opposing roles of insulin-like growth factor binding protein 3 and humanin in the regulation of testicular germ cell apoptosis.
Endocrinology 2010;151(1):350-7.
2009: Paulette M Yamada; Kuk-Wha Lee
Perspectives in mammalian IGFBP-3 biology: local vs. systemic action.
American journal of physiology. Cell physiology 2009;296(5):C954-76.
2008: Alice Chang Hoftman; Maria I Hernandez; Kuk-Wha Lee; E Richard Stiehm
Newborn illnesses caused by transplacental antibodies.
Advances in pediatrics 2008;55():271-304.
2007: Kuk-Wha Lee; Laura J Cobb; Vladislava Paharkova-Vatchkova; Bingrong Liu; Jeffrey Milbrandt; Pinchas Cohen
Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3.
Carcinogenesis 2007;28(8):1653-8.
2007: Bin Liu; Kuk-Wha Lee; Makoto Anzo; B Zhang; X Zi; Y Tao; L Shiry; M Pollak; S Lin; Pinchas Cohen
Insulin-like growth factor-binding protein-3 inhibition of prostate cancer growth involves suppression of angiogenesis.
Oncogene 2007;26(12):1811-9.
2007: Hae Soon Kim; Omar Ali; Melanie Shim; Kuk-Wha Lee; Patricia Vuguin; Radhika Muzumdar; Nir Barzilai; Pinchas Cohen
Insulin-like growth factor binding protein-3 induces insulin resistance in adipocytes in vitro and in rats in vivo.
Pediatric research 2007;61(2):159-64.
2006: Laura J Cobb; Bingrong Liu; Kuk-Wha Lee; Pinchas Cohen
Phosphorylation by DNA-dependent protein kinase is critical for apoptosis induction by insulin-like growth factor binding protein-3.
Cancer research 2006;66(22):10878-84.
2005: Bingrong Liu; Kuk-Wha Lee; Heju Li; Liqun Ma; George L Lin; Roshantha A S Chandraratna; Pinchas Cohen
Combination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(13):4851-6.
2005: Kuk-Wha Lee; Liqun Ma; Xinmin Yan; Bingrong Liu; Xiao-kun Zhang; Pinchas Cohen
Rapid apoptosis induction by IGFBP-3 involves an insulin-like growth factor-independent nucleomitochondrial translocation of RXRalpha/Nur77.
The Journal of biological chemistry 2005;280(17):16942-8.
2004: Kuk-Wha Lee; Phillip Dk Lee
Growth hormone deficiency (GHD): a new association in Peters' Plus Syndrome (PPS).
American journal of medical genetics. Part A 2004;124A(4):388-91.
2004: Kuk-Wha Lee; Bingrong Liu; Liqun Ma; Heju Li; Peter Bang; H Phillip Koeffler; Pinchas Cohen
Cellular internalization of insulin-like growth factor binding protein-3: distinct endocytic pathways facilitate re-uptake and nuclear localization.
The Journal of biological chemistry 2004;279(1):469-76.
2003: Maaria Ikonen; Bingrong Liu; Yuichi Hashimoto; Liqun Ma; Kuk-Wha Lee; Takako Niikura; Ikuo Nishimoto; Pinchas Cohen
Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):13042-7.
2003: Kuk-Wha Lee; Pinchas Cohen
Individualized growth hormone therapy in children: advances beyond weight-based dosing.
Journal of pediatric endocrinology & metabolism : JPEM 2003;16 Suppl 3():625-30.
2002: Kuk-Wha Lee; Pinchas Cohen
Nuclear effects: unexpected intracellular actions of insulin-like growth factor binding protein-3.
The Journal of endocrinology 2002;175(1):33-40.
2002: Roopmathy Rajah; Kuk-Wha Lee; Pinchas Cohen
Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002;13(4):163-71.
2001: Kuk-Wha Lee; Pinchas Cohen
Individualizing growth hormone dosing in children.
Hormone research 2001;56 Suppl 1():29-34.
1999: Lawrence A Wetterau; M G Moore; Kuk-Wha Lee; M L Shim; Pinchas Cohen
Novel aspects of the insulin-like growth factor binding proteins.
Molecular genetics and metabolism 1999;68(2):161-81.