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Michael Lee

Research Profile

Chemicals & Drugs

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Publications

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Barry Murphy; Katie Anderson; Charles Borissow; Patrick Caffrey; Gerald Griffith; Jessica Hearn; Odubunmi Ibrahim; Naseem Khan; Natalie Lamburn; Michael Lee; Katherine Pugh; Bernard Rawlings
Isolation and characterisation of amphotericin B analogues and truncated polyketide intermediates produced by genetic engineering of Streptomyces nodosus.
Glenn A Burley; David L Davies; Gerry A Griffith; Michael Lee; Kuldip Singh
Cu-catalyzed N-alkynylation of imidazoles, benzimidazoles, indazoles, and pyrazoles using PEG as solvent medium.
Nishma Chauhan; Sarah J Thackray; Sara A Rafice; Graham Eaton; Michael Lee; Igor Efimov; Jaswir Kaur; Paul R Jenkins; Christopher G Mowat; Stephen K Chapman; Emma Lloyd Raven
Reassessment of the reaction mechanism in the heme dioxygenases.

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All Publications

2010: Barry Murphy; Katie Anderson; Charles Borissow; Patrick Caffrey; Gerald Griffith; Jessica Hearn; Odubunmi Ibrahim; Naseem Khan; Natalie Lamburn; Michael Lee; Katherine Pugh; Bernard Rawlings
Isolation and characterisation of amphotericin B analogues and truncated polyketide intermediates produced by genetic engineering of Streptomyces nodosus.
Organic & biomolecular chemistry 2010;8(16):3758-70.
2010: Glenn A Burley; David L Davies; Gerry A Griffith; Michael Lee; Kuldip Singh
Cu-catalyzed N-alkynylation of imidazoles, benzimidazoles, indazoles, and pyrazoles using PEG as solvent medium.
The Journal of organic chemistry 2010;75(3):980-3.
2009: Nishma Chauhan; Sarah J Thackray; Sara A Rafice; Graham Eaton; Michael Lee; Igor Efimov; Jaswir Kaur; Paul R Jenkins; Christopher G Mowat; Stephen K Chapman; Emma Lloyd Raven
Reassessment of the reaction mechanism in the heme dioxygenases.
Journal of the American Chemical Society 2009;131(12):4186-7.
2008: Parvinder Hothi; sam hay; Anna Roujeinikova; Michael J Sutcliffe; Michael Lee; David Leys; Paul M Cullis; Nigel S Scrutton
Driving force analysis of proton tunnelling across a reactivity series for an enzyme-substrate complex.
Chembiochem : a European journal of chemical biology 2008;9(17):2839-45.
2008: Parvinder Hothi; Michael Lee; Paul M Cullis; David Leys; Nigel S Scrutton
Catalysis by the isolated tryptophan tryptophylquinone-containing subunit of aromatic amine dehydrogenase is distinct from native enzyme and synthetic model compounds and allows further probing of TTQ mechanism.
Biochemistry 2008;47(1):183-94.
2007: Parvinder Hothi; Anna Roujeinikova; Khalid Abu Khadra; Michael Lee; Paul M Cullis; David Leys; Nigel S Scrutton
Isotope effects reveal that para-substituted benzylamines are poor reactivity probes of the quinoprotein mechanism for aromatic amine dehydrogenase.
Biochemistry 2007;46(32):9250-9.
2001: Paul M Cullis; John Fawcett; Gerry A Griffith; Martin J P Harger; Michael Lee
Mechanism and stereochemistry of diphosphate formation from dioxaphosphorinanes: a critical reassessment.
Journal of the American Chemical Society 2001;123(18):4147-54.