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Myung Lee

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Young H Choi; Myung G Lee
Pharmacokinetic and pharmacodynamic interaction between nifedipine and metformin in rats: competitive inhibition for metabolism of nifedipine and metformin by each other via CYP isozymes.
Si H Yang; Dae Y Lee; Joo H Lee; Myung G Lee; Koon C Lyuk; So H Kim
Effects of morin on the pharmacokinetics of docetaxel in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors.
Young S Lee; Young H Choi; In S Yoon; Tae K Kim; Keun H Ryu; Bong-Y Lee; Myung G Lee
Pharmacokinetics of mirodenafil and its two metabolites, SK3541 and SK3544, in spontaneously or DOCA-salt-induced hypertensive rats.

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All Publications

2012: Young H Choi; Myung G Lee
Pharmacokinetic and pharmacodynamic interaction between nifedipine and metformin in rats: competitive inhibition for metabolism of nifedipine and metformin by each other via CYP isozymes.
Xenobiotica; the fate of foreign compounds in biological systems 2012;42(5):483-95.
2011: Si H Yang; Dae Y Lee; Joo H Lee; Myung G Lee; Koon C Lyuk; So H Kim
Effects of morin on the pharmacokinetics of docetaxel in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors.
Archives of pharmacal research 2011;34(10):1729-34.
2011: Young S Lee; Young H Choi; In S Yoon; Tae K Kim; Keun H Ryu; Bong-Y Lee; Myung G Lee
Pharmacokinetics of mirodenafil and its two metabolites, SK3541 and SK3544, in spontaneously or DOCA-salt-induced hypertensive rats.
Biopharmaceutics & drug disposition 2011;32(1):38-49.
2011: Hee E Kang; Se I Sohn; Seung R Baek; JW Lee; Myung G Lee
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of liquiritigenin and its two glucuronides, M1 and M2, in rats.
The Journal of pharmacy and pharmacology 2011;63(1):49-57.
2010: Hee E Kang; Se I Sohn; Seung R Baek; JW Lee; Myung G Lee
Liquiritigenin pharmacokinetics in a rat model of diabetes mellitus induced by streptozotocin: greater formation of glucuronides in the liver, especially M2, due to increased hepatic uridine 5'-diphosphoglucuronic acid level.
Metabolism: clinical and experimental 2010;59(10):1472-80.
2010: Young H Choi; Jung H Suh; Joo H Lee; Il H Cho; Myung G Lee
Effects of tesmilifene, a substrate of CYP3A and an inhibitor of P-glycoprotein, on the pharmacokinetics of intravenous and oral docetaxel in rats.
The Journal of pharmacy and pharmacology 2010;62(8):1084-8.
2010: Joo H Lee; Young H Choi; Jung H Suh; Hee E Kang; Tae H Lee; Il H Cho; Myung G Lee
Dose-dependent pharmacokinetics of SP-8203 in rats.
Biopharmaceutics & drug disposition 2010;31(5-6):358-61.
2010: Hee E Kang; Hye J Chung; Hyung S Kim; Jee W Lee; Myung G Lee
Pharmacokinetic interaction between liquiritigenin (LQ) and DDB: increased glucuronidation of LQ in the liver possibly due to increased hepatic blood flow rate by DDB.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(1-3):181-9.
2010: Young H Choi; Inchul Lee; Myung G Lee
Slower clearance of intravenous metformin in rats with acute renal failure induced by uranyl nitrate: contribution of slower renal and non-renal clearances.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(1-3):1-7.
2010: Joo H Lee; Si H Yang; Jung M Oh; Myung G Lee
Pharmacokinetics of drugs in rats with diabetes mellitus induced by alloxan or streptozocin: comparison with those in patients with type I diabetes mellitus.
The Journal of pharmacy and pharmacology 2010;62(1):1-23.
2009: Dae Y Lee; Hye J Chung; Young H Choi; Unji Lee; So H Kim; Inchul Lee; Myung G Lee
Pharmacokinetics of ipriflavone and its two metabolites, M1 and M5, after the intravenous and oral administration of ipriflavone to rat model of diabetes mellitus induced by streptozotocin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(5):465-71.
2009: Soo H Bae; Soo K Bae; Myung G Lee
Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo.
The Journal of pharmacy and pharmacology 2009;61(12):1637-42.
2009: Hye Y Jung; Hee E Kang; Young H Choi; So H Kim; Myung G Lee
Time-dependent effects of Klebsiella pneumoniae endotoxin on the pharmacokinetics of chlorzoxazone and its main metabolite, 6-hydroxychlorzoxazone, in rats: restoration of the parameters in 96 hour in KPLPS rats to control levels.
Biopharmaceutics & drug disposition 2009;30(8):485-93.
2009: Hee E Kang; Hye Y Jung; Yu K Cho; So H Kim; Se I Sohn; Seung R Baek; Myung G Lee
Pharmacokinetics of liquiritigenin in mice, rats, rabbits, and dogs, and animal scale-up.
Journal of pharmaceutical sciences 2009;98(11):4327-42.
2009: Young H Choi; Young S Lee; Tae K Kim; Bong-Y Lee; Myung G Lee
Faster clearance of mirodenafil in rats with acute renal failure induced by uranyl nitrate: contribution of increased protein expression of hepatic CYP3A1 and intestinal CYP1A1 and 3A1/2.
The Journal of pharmacy and pharmacology 2009;61(10):1325-32.
2009: Young H Choi; Young S Lee; Soo H Bae; Tae K Kim; Bong-Y Lee; Myung G Lee
Dose-dependent pharmacokinetics and first-pass effects of mirodenafil, a new erectogenic, in rats.
Biopharmaceutics & drug disposition 2009;30(6):305-17.
2009: Hye J Chung; Hee E Kang; Kyung H Yang; Sung Y Kim; Myung G Lee
Ipriflavone pharmacokinetics in mutant Nagase analbuminemic rats.
Biopharmaceutics & drug disposition 2009;30(6):294-304.
2009: Dae Y Lee; Young S Jung; Young C Kim; Sung Y Kim; Myung G Lee
Faster clearance of omeprazole in mutant Nagase analbuminemic rats: possible roles of increased protein expression of hepatic CYP1A2 and lower plasma protein binding.
Biopharmaceutics & drug disposition 2009;30(3):107-16.
2009: Soo K Bae; Kyung H Yang; Dipendra K Aryal; Yoon G Kim; Myung G Lee
Pharmacokinetics of amitriptyline and one of its metabolites, nortriptyline, in rats: little contribution of considerable hepatic first-pass effect to low bioavailability of amitriptyline due to great intestinal first-pass effect.
Journal of pharmaceutical sciences 2009;98(4):1587-601.
2009: Kyung H Yang; Young H Choi; Unji Lee; Joo H Lee; Myung G Lee
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
The Journal of pharmacy and pharmacology 2009;61(1):47-54.
2008: Joo H Lee; Yu K Cho; Young S Jung; Young C Kim; Myung G Lee
Time-dependent effects of Klebsiella pneumoniae endotoxin on the telithromycin pharmacokinetics in rats; restoration of the parameters in 96-hour KPLPS rats to the control levels.
Pulmonary pharmacology & therapeutics 2008;21(6):860-5.
2008: Young H Choi; Duck C Lee; Inchul Lee; Myung G Lee
Changes in metformin pharmacokinetics after intravenous and oral administration to rats with short-term and long-term diabetes induced by streptozotocin.
Journal of pharmaceutical sciences 2008;97(12):5363-75.
2008: Hye J Chung; Hee E Kang; Eun J Bae; Inchul Lee; Sang G Kim; Myung G Lee
Effects of E. Coli lipopolysaccharide on the pharmacokinetics of ipriflavone and its metabolites, M1 and M5, after intravenous and oral administration of ipriflavone to rats: decreased metabolism of ipriflavone due to decreased expression of hepatic CYP1A2 and 2C11.
Journal of pharmaceutical sciences 2008;97(11):5024-36.
2008: Si H Yang; Myung G Lee
Dose-independent pharmacokinetics of ondansetron in rats: contribution of hepatic and intestinal first-pass effects to low bioavailability.
Biopharmaceutics & drug disposition 2008;29(7):414-26.
2008: Si H Yang; Kyung H Yang; Myung G Lee
Gender differences in ondansetron pharmacokinetics in rats.
Biopharmaceutics & drug disposition 2008;29(7):406-13.
2008: Joo H Lee; Myung G Lee
Telithromycin pharmacokinetics in rat model of diabetes mellitus induced by alloxan or streptozotocin.
Pharmaceutical research 2008;25(8):1915-24.
2008: Si H Yang; Myung G Lee
Effects of cytochrome P450 (CYP) inducers and inhibitors on ondansetron pharmacokinetics in rats: involvement of hepatic CYP2D subfamily and 3A1/2 in ondansetron metabolism.
The Journal of pharmacy and pharmacology 2008;60(7):853-61.
2008: Dae Y Lee; Young S Jung; Hyun S Shin; Inchul Lee; Young C Kim; Myung G Lee
Faster clearance of omeprazole in rats with acute renal failure induced by uranyl nitrate: contribution of increased expression of hepatic cytochrome P450 (CYP) 3A1 and intestinal CYP1A and 3A subfamilies.
The Journal of pharmacy and pharmacology 2008;60(7):843-51.
2008: Choong Y Ahn; Soo K Bae; Yi-Sook Jung; Inchul Lee; Young C Kim; Myung G Lee; Wan G Shin
Pharmacokinetic parameters of chlorzoxazone and its main metabolite, 6-hydroxychlorzoxazone, after intravenous and oral administration of chlorzoxazone to liver cirrhotic rats with diabetes mellitus.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(7):1233-41.
2008: Kyung H Yang; Yi-Sook Jung; Dae Y Lee; Joo H Lee; Young C Kim; Myung G Lee
Time-dependent effects of Klebsiella pneumoniae endotoxin (KPLPS) on the pharmacokinetics of theophylline in rats: return of the parameters in 96-hour KPLPS rats to the control levels.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(5):811-5.
2008: Joo H Lee; Yu K Cho; Young S Jung; Young C Kim; Myung G Lee
Effects of Escherichia coli lipopolysaccharide on telithromycin pharmacokinetics in rats: inhibition of metabolism via CYP3A.
Antimicrobial agents and chemotherapy 2008;52(3):1046-51.
2008: Young H Choi; Inchul Lee; Myung G Lee
Effects of cysteine on metformin pharmacokinetics in rats with protein-calorie malnutrition: partial restoration of some parameters to control levels.
The Journal of pharmacy and pharmacology 2008;60(2):153-61.
2008: Myung G Lee; Young H Choi; Inchul Lee
Effects of diabetes mellitus induced by alloxan on the pharmacokinetics of metformin in rats: restoration of pharmacokinetic parameters to the control state by insulin treatment.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2008;11(1):88-103.
2008: Kyung H Yang; Joo H Lee; Myung G Lee
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.
The Journal of pharmacy and pharmacology 2008;60(1):45-53.
2008: Yu C Kim; Hee E Kang; Myung G Lee
Pharmacokinetics of phenytoin and its metabolite, 4'-HPPH, after intravenous and oral administration of phenytoin to diabetic rats induced by alloxan or streptozotocin.
Biopharmaceutics & drug disposition 2008;29(1):51-61.
2007: Dae Y Lee; Jin W Kim; Myung G Lee
Pharmacokinetic interaction between oltipraz and omeprazole in rats: Competitive inhibition of metabolism of oltipraz by omeprazole via CYP1A1 and 3A2, and of omeprazole by oltipraz via CYP1A1/2, 2D1/2, and 3A1/2.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;32(4-5):328-39.
2007: Hye D Choi; Hee E Kang; Hye J Chung; Soo K Bae; Karen N Shin; Myung G Lee
Effects of water deprivation on the pharmacokinetics of theophylline and one of its metabolites, 1,3-dimethyluric acid, after intravenous and oral administration of aminophylline to rats.
Biopharmaceutics & drug disposition 2007;28(8):445-54.
2007: Young H Choi; Soo K Bae; Jung Mi Oh; Sun-Ok Kim; Myung G Lee
Pharmacokinetics of intravenous methotrexate in mutant Nagase analbuminemic rats.
Biopharmaceutics & drug disposition 2007;28(7):385-92.
2007: Young H Choi; Inchul Lee; Myung G Lee
Effects of water deprivation on the pharmacokinetics of metformin in rats.
Biopharmaceutics & drug disposition 2007;28(7):373-83.
2007: Soo K Bae; Si H Yang; Karen N Shin; Jae Keol Rhee; Moohi Yoo; Myung G Lee
Pharmacokinetics of DA-7218, a new oxazolidinone, and its active metabolite, DA-7157, after intravenous and oral administration of DA-7218 and DA-7157 to rats.
The Journal of pharmacy and pharmacology 2007;59(7):955-63.
2007: Young H Choi; Inchul Lee; Myung G Lee
Effects of bacterial lipopolysaccharide on the pharmacokinetics of metformin in rats.
International journal of pharmaceutics 2007;337(1-2):194-201.
2007: Joo H Lee; Myung G Lee
Effects of acute renal failure on the pharmacokinetics of telithromycin in rats: negligible effects of increase in CYP3A1 on the metabolism of telithromycin.
Biopharmaceutics & drug disposition 2007;28(4):157-66.
2007: Hye J Chung; Joo H Lee; Sung J Woo; Hee K Park; Chang Hui Koo; Myung G Lee
Pharmacokinetics of L-FMAUS, a new antiviral agent, after intravenous and oral administration to rats: contribution of gastrointestinal first-pass effect to low bioavailability.
Biopharmaceutics & drug disposition 2007;28(4):187-97.
2007: Si H Yang; Myung G Lee
Dose-independent pharmacokinetics of clindamycin after intravenous and oral administration to rats: contribution of gastric first-pass effect to low bioavailability.
International journal of pharmaceutics 2007;332(1-2):17-23.
2007: Young H Choi; Soo K Bae; Sun O Kim; Myung G Lee
Pharmacokinetics of 5-fluorouracil in mutant Nagase analbuminemic rats: faster metabolism of 5-fluorouracil via CYP1A.
Biopharmaceutics & drug disposition 2007;28(2):87-95.
2007: Dae Y Lee; Inchul Lee; Myung G Lee
Pharmacokinetics of omeprazole after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
International journal of pharmaceutics 2007;330(1-2):37-44.
2007: Dae Young Lee; Myung G Lee; Hyun Sook Shin; Inchul Lee
Changes in omeprazole pharmacokinetics in rats with diabetes induced by alloxan or streptozotocin: faster clearance of omeprazole due to induction of hepatic CYP1A2 and 3A1.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2007;10(4):420-33.
2007: Dae Y Lee; Inchul Lee; Myung G Lee
Effects of cysteine on the pharmacokinetic parameters of omeprazole in rats with protein-calorie malnutrition: partial restoration of some parameters to control levels by oral cysteine supplementation.
JPEN. Journal of parenteral and enteral nutrition 2007;31(1):37-46.
2006: Young H Choi; Sang G Kim; Myung G Lee
Dose-independent pharmacokinetics of metformin in rats: Hepatic and gastrointestinal first-pass effects.
Journal of pharmaceutical sciences 2006;95(11):2543-52.
2006: Dae Y Lee; Hyun S Shin; Inchul Lee; Myung G Lee
Pharmacokinetics of omeprazole in rats with water deprivation for 72 hours.
Biopharmaceutics & drug disposition 2006;27(8):361-70.
2006: Hye W Baek; Soo K Bae; Myung G Lee; Young T Sohn
Pharmacokinetics of chlorzoxazone in rats with diabetes: Induction of CYP2E1 on 6-hydroxychlorzoxazone formation.
Journal of pharmaceutical sciences 2006;95(11):2452-62.
2006: Hye J Chung; Myung G Lee
Pharmacokinetic changes of ipriflavone in rats with acute renal failure induced by uranyl nitrate.
Biopharmaceutics & drug disposition 2006;27(7):345-51.
2006: Hyun S Shin; Soo K Bae; Myung G Lee
Pharmacokinetics of sildenafil after intravenous and oral administration in rats: hepatic and intestinal first-pass effects.
International journal of pharmaceutics 2006;320(1-2):64-70.
2006: Dae Y Lee; Hyun S Shin; Soo K Bae; Myung G Lee
Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous omeprazole in rats.
Biopharmaceutics & drug disposition 2006;27(5):209-18.
2006: Soo K Bae; Shin J Lee; Taekrho Kim; Jin W Kim; Inchul Lee; Sang G Kim; Myung G Lee
Pharmacokinetics and therapeutic effects of oltipraz after consecutive or intermittent oral administration in rats with liver cirrhosis induced by dimethylnitrosamine.
Journal of pharmaceutical sciences 2006;95(5):985-97.
2006: Soo K Bae; Hee E Kang; Min K Kang; Jin W Kim; Taekrho Kim; Myung G Lee
Pharmacokinetics of oltipraz in mutant Nagase analbuminemic rats.
Journal of pharmaceutical sciences 2006;95(5):998-1005.
2006: Hye J Chung; Young H Choi; So H Kim; Myung G Lee
Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous ipriflavone in rats.
The Journal of pharmacy and pharmacology 2006;58(4):449-57.
2006: Soo K Bae; Yu C Kim; Jae K Lee; Jong W Kwon; Moohi Yoo; Inchul Lee; Myung G Lee
Effects of water deprivation for 72 hours on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
Biopharmaceutics & drug disposition 2006;27(3):147-56.
2006: Joo H Lee; Eun J Kim; Jong W Kwon; Moohi Yoo; Myung G Lee
Negligible pharmacokinetic interaction between oral DA-8159, a new erectogenic, and amlodipine in rats.
Biopharmaceutics & drug disposition 2006;27(3):125-31.
2006: Hyun H Kwak; Jong O Kim; Han K Chung; Seul M Choi; Jung H Kim; Jong W Kwon; Moohi Yoo; Joo H Lee; Myung G Lee
Pharmacokinetics of oral amlodipine orotate in vagotomized dogs.
Biopharmaceutics & drug disposition 2006;27(3):141-5.
2006: Hye J Chung; Young H Choi; Hye D Choi; Ji M Jang; Hyun J Shim; Moohi Yoo; Jong W Kwon; Myung G Lee
Pharmacokinetics of DA-6034, an agent for inflammatory bowel disease, in rats and dogs: Contribution of intestinal first-pass effect to low bioavailability in rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(4):363-74.
2006: Yu C Kim; Eun Y Oh; So H Kim; Myung G Lee
Pharmacokinetics of diclofenac in rat model of diabetes mellitus induced by alloxan or steptozotocin.
Biopharmaceutics & drug disposition 2006;27(2):85-92.
2006: Ka Y Choi; Yu C Kim; Myung G Lee
Mechanism of enhanced bioavailability and diuretic effect of azosemide by ascorbic acid in rats.
Life sciences 2006;78(10):1057-62.
2006: Eun J Kim; Mi Y Chung; Hye J Chung; Mi W Son; Jong W Kwon; Moohi Yoo; Myung G Lee
Pharmacokinetics of 7-carboxymethyloxy-3',4',5-trimethoxy flavone (DA-6034), a derivative of flavonoid, in mouse and rat models of chemically-induced inflammatory bowel disease.
The Journal of pharmacy and pharmacology 2006;58(1):27-35.
2006: Soo K Bae; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Effects of acute renal failure on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
Biopharmaceutics & drug disposition 2006;27(1):29-37.
2006: Si H Yang; Soo K Bae; Jong W Kwon; Moohi Yoo; Myung G Lee
Gender differences in the pharmacokinetics of DA-6034, a derivative of flavonoids, in rats.
Biopharmaceutics & drug disposition 2006;27(1):47-51.
2005: Joo H Lee; Soo K Bae; Jong W Kwon; Won Bae Kim; Myung G Lee
Effects of omeprazole or cola beverage on the pharmacokinetics of oral DA-8159, a new erectogenic, in rats.
Biopharmaceutics & drug disposition 2005;26(9):411-6.
2005: Yu C Kim; Eun Y Oh; So H Kim; Myung G Lee
Pharmacokinetics and pharmacodynamics of intravenous torasemide in diabetic rats induced by alloxan or streptozotocin.
Biopharmaceutics & drug disposition 2005;26(8):371-8.
2005: Yu C Kim; Hyun J Shim; Joo H Lee; Dong S Kim; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Pharmacokinetic changes of DA-8159, a new erectogenic, and one of its metabolites, DA-8164 after intravenous and oral administration of DA-8159 to spontaneously hypertensive rats and DOCA-salt-induced hypertensive rats.
Biopharmaceutics & drug disposition 2005;26(7):309-20.
2005: Hyun J Shim; Yu C Kim; Joo H Lee; Jong W Kwon; Won Bae Kim; Yoon G Kim; So H Kim; Myung G Lee
Interspecies pharmacokinetic scaling of DA-8159, a new erectogenic, in mice, rats, rabbits and dogs, and prediction of human pharmacokinetics.
Biopharmaceutics & drug disposition 2005;26(7):269-77.
2005: Yu C Kim; Hyun J Shim; Joo H Lee; Soon H Kim; Jong W Kwon; Won Bae Kim; Myung G Lee
Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous DA-8159, a new erectogenic, in rats.
Biopharmaceutics & drug disposition 2005;26(6):233-41.
2005: Dae Y Lee; Shin J Lee; Myung G Lee
Effects of enzyme inducers and inhibitors on the pharmacokinetics of intravenous torasemide in rats.
International journal of pharmaceutics 2005;298(1):38-46.
2005: Soo K Bae; Si H Yang; Jin W Kim; Taekrho Kim; Jong W Kwon; Myung G Lee
Effects of cysteine on the pharmacokinetics of oltipraz in rats with protein-calorie malnutrition.
Journal of pharmaceutical sciences 2005;94(7):1484-93.
2005: Dae Y Lee; Ji Y Kim; Yu C Kim; Jong W Kwon; Won Bae Kim; Myung G Lee
Dose-independent pharmacokinetics of torasemide after intravenous and oral administration to rats.
Biopharmaceutics & drug disposition 2005;26(5):173-82.
2005: Yu C Kim; Joo H Lee; So H Kim; Myung G Lee
Effect of CYP3A1(23) induction on clarithromycin pharmacokinetics in rats with diabetes mellitus.
Antimicrobial agents and chemotherapy 2005;49(6):2528-32.
2005: Soo K Bae; Si H Yang; Shin J Lee; Jong W Kwon; Won Bae Kim; Duk-Chul Lee; Myung G Lee
Pharmacokinetic changes of DA-7867, a new oxazolidinone, after intravenous and oral administration to rats with short-term and long-term diabetes mellitus induced by streptozotocin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;25(2-3):337-45.
2005: Joo H Lee; Yu C Kim; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetics of DA-8159, a new erectogenic, administered at 10:00 h versus 22:00 h in rats.
International journal of pharmaceutics 2005;296(1-2):94-102.
2005: Hyun J Shim; Yu C Kim; Joo H Lee; Kyung J Park; Jong W Kwon; Won Bae Kim; Myung G Lee
Species differences in the formation of DA-8164 after intravenous and/or oral administration of DA-8159, a new erectogenic, to mice, rats, rabbits, dogs and humans.
Biopharmaceutics & drug disposition 2005;26(4):161-6.
2005: Soo K Bae; Jin W Kim; Young H Kim; Yoon G Kim; Sang G Kim; Myung G Lee
Hepatic and intestinal first-pass effects of oltipraz in rats.
Biopharmaceutics & drug disposition 2005;26(4):129-34.
2005: Soo K Bae; Shin J Lee; Yoon G Kim; So H Kim; Jin W Kim; Taekrho Kim; Myung G Lee
Interspecies pharmacokinetic scaling of oltipraz in mice, rats, rabbits and dogs, and prediction of human pharmacokinetics.
Biopharmaceutics & drug disposition 2005;26(3):99-115.
2005: Young H Choi; Ae K Lee; Soo K Bae; Sun O Kim; Myung G Lee
Pharmacokinetics of 5-fluorouracil in rats with diabetes mellitus induced by streptozotocin.
Biopharmaceutics & drug disposition 2005;26(3):93-8.
2005: Soo K Bae; Eun J Kim; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Excretion and metabolism of DA-7867, a new oxazolidinone, in rats.
Biopharmaceutics & drug disposition 2005;26(2):67-75.
2005: Soo K Bae; Shin J Lee; Jin W Kim; Young H Kim; Sang G Kim; Myung G Lee
Pharmacokinetics of oltipraz after intravenous and oral administration in rats with dehydration for 72 hours.
Biopharmaceutics & drug disposition 2005;26(2):77-83.
2005: Joo H Lee; Yu C Kim; Jong W Kwon; Won Bae Kim; Myung G Lee
Effects of bacterial lipopolysaccharide on the pharmacokinetics of DA-8159, a new erectogenic, in rats.
Research communications in molecular pathology and pharmacology 2005;117-118():179-87.
2004: Hyun J Shim; Yu C Kim; Joo H Lee; Byoung Ok Ahn; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Pharmacokinetics of intravenous and oral DA-8159, a new erectogenic, in rats with protein-calorie malnutrition.
The Journal of pharmacy and pharmacology 2004;56(12):1543-50.
2004: Ae K Lee; Joo H Lee; Jong W Kwon; Won Bae Kim; Sang G Kim; So H Kim; Myung G Lee
Pharmacokinetics of clarithromycin in rats with acute renal failure induced by uranyl nitrate.
Biopharmaceutics & drug disposition 2004;25(6):273-82.
2004: Soo K Bae; Dae Y Lee; Ae K Lee; Jong W Kwon; Inchul Lee; Suk-Jae Chung; Sang G Kim; Chang-Koo Shim; Myung G Lee
Effects of cysteine on the pharmacokinetics of intravenous torasemide in rats with protein-calorie malnutrition.
Journal of pharmaceutical sciences 2004;93(9):2388-98.
2004: Yu C Kim; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Pharmacokinetic changes of DA-8159, a new erectogenic, after intravenous and oral administration to rats with diabetes mellitus induced by streptozotocin.
Journal of pharmaceutical sciences 2004;93(9):2374-87.
2004: Soo K Bae; Shin J Lee; Jong W Kwon; Won Bae Kim; Inchul Lee; Myung G Lee
Effects of bacterial lipopolysaccharide on the pharmacokinetics of DA-7867, a new oxazolidinone, in rats.
Journal of pharmaceutical sciences 2004;93(9):2364-73.
2004: Soo K Bae; Shin J Lee; Jin W Kim; Young H Kim; Sang G Kim; Myung G Lee
Effects of acute renal failure on the pharmacokinetics of oltipraz in rats.
Journal of pharmaceutical sciences 2004;93(9):2353-63.
2004: Yu C Kim; Myung G Lee; Seong-Hee Ko; So H Kim
Effect of intravenous infusion time on the pharmacokinetics and pharmacodynamics of the same total dose of torasemide in rabbits.
Biopharmaceutics & drug disposition 2004;25(5):211-8.
2004: Soo K Bae; Shin J Lee; Jang Y Lee; Youngsoo Lee; Inchul Lee; Sang G Kim; Myung G Lee
Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine.
International journal of pharmaceutics 2004;275(1-2):227-38.
2004: Jee H Shin; Ka Y Choi; Yu C Kim; Myung G Lee
Dose-dependent pharmacokinetics of itraconazole after intravenous or oral administration to rats: intestinal first-pass effect.
Antimicrobial agents and chemotherapy 2004;48(5):1756-62.
2004: Sun-O Kim; Sang-H Kwak; Byung Ho Lee; Dong-H Lee; Hong Lim; Sung-E Yoo; Hye J Chung; Myung G Lee
Dose-dependent pharmacokinetics of KR-31378, a new neuroprotective agent for ischaemia-reperfusion damage in dogs.
Biopharmaceutics & drug disposition 2004;25(3):143-8.
2004: Hyun J Shim; Yu C Kim; Eun J Kim; Dong G Kim; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetic changes of DA-8159, a new erectogenic, after intravenous and oral administration to rats with acute renal failure induced by uranyl nitrate.
Biopharmaceutics & drug disposition 2004;25(3):137-42.
2004: Soo K Bae; Won-S Chung; Eun J Kim; Jae Keol Rhee; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetics, blood partition and protein binding of DA-7867, a new oxazolidinone.
Biopharmaceutics & drug disposition 2004;25(3):127-35.
2004: Soo K Bae; Won-Suk Chung; Eun J Kim; Jae Keol Rhee; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetics of DA-7867, a new oxazolidinone, after intravenous or oral administration to rats: intestinal first-pass effect.
Antimicrobial agents and chemotherapy 2004;48(2):659-62.
2004: Joo H Lee; Jee H Shin; Myung G Lee
Pharmacokinetics, blood partition, and tissue distribution of itraconazole.
Research communications in molecular pathology and pharmacology 2004;115-116():203-15.
2004: Eun J Lee; Eun J Kim; Yoon G Kim; Hye C Chung; So H Kim; Dong H Kim; Inchul Lees; Sang G Kim; Myung G Lee
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of 2-(allylthio) pyrazine, a chemoprotective agent, in rats: the role of CYP3A23 induction.
Research communications in molecular pathology and pharmacology 2004;115-116():111-21.
2003: Hyun J Shim; Yu C Kim; Ji M Jang; Kyung J Park; Dong H Kim; Kyung Koo Kang; Byoung Ok Ahn; Jong W Kwon; Won Bae Kim; Myung G Lee
Subacute toxicities and toxicokinetics of DA-8159, a new phosphodiesterase type V inhibitor, after single and 4-week repeated oral administration in rats.
Biopharmaceutics & drug disposition 2003;24(9):409-18.
2003: Hyun J Shim; Yu C Kim; Kyung J Park; Dong S Kim; Jong W Kwon; Won Bae Kim; Myung G Lee
Pharmacokinetics of DA-8159, a new erectogenic, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects.
Journal of pharmaceutical sciences 2003;92(11):2185-95.
2003: Ok Kyung Suh; So H Kim; Myung G Lee
Pharmacokinetics and pharmacodynamics of azosemide.
Biopharmaceutics & drug disposition 2003;24(7):275-97.
2003: Choong Y Ahn; Eun J Kim; Jong W Kwon; Suk-Jae Chung; Sang G Kim; Chang-Koo Shim; Myung G Lee
Effects of cysteine on the pharmacokinetics of intravenous clarithromycin in rats with protein-calorie malnutrition.
Life sciences 2003;73(14):1783-94.
2003: Choong Y Ahn; Eun J Kim; Inchul Lee; Jong W Kwon; Won Bae Kim; Sang G Kim; Myung G Lee
Effects of glucose on the pharmacokinetics of intravenous chlorzoxazone in rats with acute renal failure induced by uranyl nitrate.
Journal of pharmaceutical sciences 2003;92(8):1604-13.
2003: Eun J Kim; Soo K Bae; Hee J Kim; Yoon G Kim; Sun-O Kim; Dong H Lee; Hong Lim; Myung G Lee
Dose-independent pharmacokinetics of a candidate for diabetic neuropathy, SR-4668, after intravenous and oral administration to rats: Intestinal first-pass effect.
Journal of pharmaceutical sciences 2003;92(5):1112-24.
2003: Ae K Lee; Choong Y Ahn; Eun J Kim; Jong W Kwon; Sang G Kim; Suk-Jae Chung; Chang-Koo Shim; Myung G Lee
Effects of cysteine on the pharmacokinetics of itraconazole in rats with protein-calorie malnutrition.
Biopharmaceutics & drug disposition 2003;24(2):63-70.
2003: Yu C Kim; Yoon G Kim; Eun J Kim; Min K Cho; Sang G Kim; Myung G Lee
Pharmacokinetics of intravenous chlorzoxazone in rats with dehydration and rehydration: effects of food intakes.
Biopharmaceutics & drug disposition 2003;24(2):53-61.
2003: Eun J Kim; Ae K Lee; So H Kim; Sang G Kim; Myung G Lee
Pharmacokinetics and pharmacodynamics of intravenous azosemide in mutant Nagase analbuminemic rats.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(2):194-201.
2003: Yoon G Kim; Sang K Kim; Jong W Kwon; Ock Jin Park; Sang G Kim; Young C Kim; Myung G Lee
Effects of cysteine on amino acid concentrations and transsulfuration enzyme activities in rat liver with protein-calorie malnutrition.
Life sciences 2003;72(10):1171-81.
2003: Ae K Lee; Eun J Kim; Myung G Lee
Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous torasemide in rats.
Research communications in molecular pathology and pharmacology 2003;113-114():193-200.
2003: Eun J Kim; Myung G Lee
Pharmacokinetics and pharmacodynamics of intravenous trasemide in mutant Nagase analbuminemic rats.
Biopharmaceutics & drug disposition 2003;24(1):27-35.
2003: Mi H Lee; Soo K Bae; Eun J Kim; Yoon G Kim; Sun-O Kim; Dong H Lee; Hong Lim; Sung-E Yoo; Myung G Lee
Dose-independent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31543, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects.
Journal of pharmaceutical sciences 2003;92(1):190-201.
2002: Hee J Kim; Ae K Lee; Yoon G Kim; Seong C Bu; So H Kim; Chae H Yang; Ok Kyung Suh; Sang G Kim; Myung G Lee
Influence of 4-week and 8-week exercise training on the pharmacokinetics and pharmacodynamics of intravenous and oral azosemide in rats.
Life sciences 2002;70(19):2299-319.
2002: Eun J Lee; Eun J Kim; Yoon G Kim; Hye C Chung; So H Kim; Dong H Kim; Inchul Lee; Sang G Kim; Myung G Lee
Pharmacokinetic changes of intravenous 2-(allylthio) pyrazine, a chemoprotective agent, in rats with acute renal failure induced by uranyl nitrate.
Research communications in molecular pathology and pharmacology 2002;111(5-6):225-36.
2000: I J Son; Y J Moon; Myung G Lee; Young-Taek Sohn
Pharmacokinetic changes of intravenous tacrolimus in rats with uranyl nitrate-induced acute renal failure.
Research communications in molecular pathology and pharmacology 2000;108(5-6):359-68.
2000: I J Son; Y J Moon; Myung G Lee; Young-Taek Sohn
No effect of water deprivation for 48 hours on the pharmacokiinetics of intravenous tacrolimus in rats.
Research communications in molecular pathology and pharmacology 2000;107(3-4):279-89.